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LTAAIGSQRQALAMIDLSRSTWHYRTNPRPPVSDPLPQKHRAYPSRIDEADRAVIRDKILAGWEAGSSVD HAFAASWDEGVMLASRRSWWRIAAAIEDQSARPVAPTRSTSKTPRQAPVLKATGPQQIWSWDITDLRSPW RGVAFKAYSILDIYSRKIVGWRVEERECDDLAVDMFEAAFAGHGLPAVVHADSGPAMRSTVLKDLLAGLK IGQTHNRPRVSNDNPFSESEFRTMKYRPNYPGVFTDLDSARAWVSAYVSWYNQHHRHSGVELFTPDSVHD GTWAQLWDRRDTALQAYYDAHPERFRNRPRTKSPSPVVGINLPTENDPDRLQAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4078 | - | - | 100% (334) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_1742 | - | 0.0 | 100.00% (334) | integrase catalytic subunit |
| M. gilvum PYR-GCK | Mflv_0384 | - | 0.0 | 100.00% (334) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3460c | - | 2e-43 | 35.00% (280) | transposase |
| M. tuberculosis H37Rv | Rv3430c | - | 5e-44 | 35.36% (280) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2548 | - | 1e-08 | 25.36% (209) | transposase, ISMyma03_aa2 |
| M. avium 104 | MAV_1454 | - | 8e-11 | 27.75% (191) | transposase |
| M. smegmatis MC2 155 | MSMEG_1862 | - | 6e-49 | 37.67% (300) | transposase |
| M. thermoresistible (build 8) | TH_4372 | - | 2e-09 | 24.26% (235) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0306 | - | 1e-152 | 78.19% (321) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4078|M.gilvum_PYR-GCK ------------MTAAIGSQRQALAMIDLSRSTWHYRTNP-----RPPVS
Mvan_0306|M.vanbaalenii_PYR-1 -------------------------MIELSRSTWHYRSHP-----RPRVA
Mb3460c|M.bovis_AF2122/97 MIDTAIEEMIPLIGVRAACAATGRAPASYYRAHSKRLSAQSDTFTSTAVT
Rv3430c|M.tuberculosis_H37Rv MIDTAIEEMIPLIGVRAACAATGRAPASYYRAHSKRLSAQSDTFTSTAVT
MSMEG_1862|M.smegmatis_MC2_155 -MDAYNDLRDIQIPTRKAAEVTG-----MHRSTATRRAKP-----APAPA
MMAR_2548|M.marinum_M --------------------MLTEHGIKISPSTYYEWMKR-----TPSKQ
MAV_1454|M.avium_104 ----------------------------MALSTYYDTKAR-----VPSAR
TH_4372|M.thermoresistible__bu ----VSRFELIAAECAHHDVSKLAELLGVSRSGYYAWAARQ---RRVELS
:
Mflv_4078|M.gilvum_PYR-GCK DPLPQKHRAYPSRIDEADRAVIRDKILAGWEAGSSVDHAFAASWDEGVML
Mvan_0306|M.vanbaalenii_PYR-1 NPMPHKDRAYPSRIGVADRAVIAEQIIAGWLAGVSVDQSFATMWDAGVLL
Mb3460c|M.bovis_AF2122/97 DPSGPRESAQPRALSAAEREHVLAVLNSQRFADMAPAVVYATLLDEGIYL
Rv3430c|M.tuberculosis_H37Rv DPSGPRESAQPRALSAAEREHVLAVLNSQRFADMAPAVVYATLLDEGIYL
MSMEG_1862|M.smegmatis_MC2_155 DR-APR-PVPVNKLTESECARVVEVLNSARFVDAAPMQVWATLLDEGSYL
MMAR_2548|M.marinum_M QLRDEAVTASIKEFRERNPLNKTLGSRKVWIKLRGDGMDVARCTVERLMQ
MAV_1454|M.avium_104 ALRDAVLGPALCQLWKDN--YCVYGARKLWKTARREGHDVGRDQVARLMR
TH_4372|M.thermoresistible__bu PRQQWRRDLEVKILAHWQASGRTYGSPRITADLHAEGVGVSENTVAKIMA
: : .
Mflv_4078|M.gilvum_PYR-GCK ASRRSWWRIAAAIEDQSARPVAPTRSTSKTPRQAPVLKATGPQQIWSWDI
Mvan_0306|M.vanbaalenii_PYR-1 ASRRSWWRIAAVI-DQSLRPVAPTRATNKTPRSAPVLKATGPQQIWSWDI
Mb3460c|M.bovis_AF2122/97 CSESTMYRLLRERGQTGDR----RRQATHPAAVKPELVAHQPNSVWSWDI
Rv3430c|M.tuberculosis_H37Rv CSESTMYRLLRERGQTGDR----RRQATHPAAVKPELVAHQPNSVWSWDI
MSMEG_1862|M.smegmatis_MC2_155 CSVSTMYRVLNANKLVKER----RRLARHRKAVCPELVATAPRQVYSWDI
MMAR_2548|M.marinum_M ANRWQGARYGGAPKTTIQD----EKAQRATDLVDRVFAAPAPNRLWVADF
MAV_1454|M.avium_104 AAGIEGVRRGKRVRTTKPD----PAAARHPDLVKRNFTATAPNQLWVTDL
TH_4372|M.thermoresistible__bu EMGIEGISPRTFKVKTTQVD---PTASFPPDRVGRAFDQGRLDAVWTSDI
: :: *:
Mflv_4078|M.gilvum_PYR-GCK TDLRSPWRGVAFKAYSILDIYSRKIVGWRVEERECDDLAVDMFEAAFAGH
Mvan_0306|M.vanbaalenii_PYR-1 TDLHSPWRGVSFKTYSIVDIFSRKIVGWRVEERECDDLAVEMFKTAIAEH
Mb3460c|M.bovis_AF2122/97 TKLRGPAKWSYYYLYVILDIFSRYVVGWMVASRESKVLAERLIAQTLAAQ
Rv3430c|M.tuberculosis_H37Rv TKLRGPAKWSYYYLYVILDIFSRYVVGWMVASRESKVLAERLIAQTLAAQ
MSMEG_1862|M.smegmatis_MC2_155 TKLAGPVKGVYYDAYVMIDIYSRYIVGVHVHARECGQLAKEMMEQIFGTY
MMAR_2548|M.marinum_M TYCP-TWAGMVYVAF-VIDAFARRVIGWRAATSMKTALVIDALEHAFFTR
MAV_1454|M.avium_104 TFVP-TWAGVAYVCF-IIDAYSRMIVGWRVASHMRTSMVLDALEMARWSR
TH_4372|M.thermoresistible__bu TYLT-CGEGDAYLCA-IRDEHSRRVLGWSLADHMRTELVEAAVDAAVFTR
* : : * .:* ::* :. .
Mflv_4078|M.gilvum_PYR-GCK GLPA-------VVHADSGPAMRSTVLKDLLAGLKIGQTHNRPRVSNDNPF
Mvan_0306|M.vanbaalenii_PYR-1 GPPA-------VVHADSGPAMRSTVLKDLLAGLGIGQTHIRPHVSNDNPF
Mb3460c|M.bovis_AF2122/97 HISAD----QLTLHADRGSSMSSKPVALLLADLGVTKSHSHPHTSNDNPL
Rv3430c|M.tuberculosis_H37Rv HISAD----QLTLHADRGSSMSSKPVALLLADLGVTKSHSRPHTSNDNPL
MSMEG_1862|M.smegmatis_MC2_155 GIPH-------VVHADRGTSMTSNTVAGLLSDLGVIRSHSRPKVSNDNPY
MMAR_2548|M.marinum_M AQEGFTDLSGLVAHSDAGSQYTSIAFTTRLIDAGIDASVGSVADAYDNAL
MAV_1454|M.avium_104 GNM----LPGLRCHSDAGSQFTSIRYGERLAEIGAVPSIGTVGDSFDNAL
TH_4372|M.thermoresistible__bu AGHVAG----TVMHSDRGSQFTSYDMAQACTRHGLLRSMGATGICWDNAG
*:* *. * : . **.
Mflv_4078|M.gilvum_PYR-GCK SESEFRTMKYRPNYP----GVFTDLDSARAWVSAYVSWYNQHHRHSGVEL
Mvan_0306|M.vanbaalenii_PYR-1 SESEFRTMKYRPNYP----GVFDDLNTAHAWVQAYVRWYNQHHRHSGIAL
Mb3460c|M.bovis_AF2122/97 SEAQFKTLKYRPDFP----KRFESIEAARVHCDRFFGWYNHEHKHSGIGL
Rv3430c|M.tuberculosis_H37Rv SEAQFKTLKYRPDFP----KRFESIEAARVHCDRFFGWYNHEHKHSGIGL
MSMEG_1862|M.smegmatis_MC2_155 SESWFKTLKYAPAFP----ERFESIHHARDFMDRFVQWYNHEHRHSGIGL
MMAR_2548|M.marinum_M AETTVGSFKNELIR---RQGPWRDVDHVEIGTLNWVDWFNNERPHEYLAD
MAV_1454|M.avium_104 AETVNGYYKAELIYGPARTGPWKTVEDVELATLSWVYWHNTSRLHSYLGD
TH_4372|M.thermoresistible__bu SESLWSTVKHEYYKR----HAFTTYANLTAGLDNYIRFYNHERRHSSLGM
:*: * : :. :.* : *. :
Mflv_4078|M.gilvum_PYR-GCK FTPDSVHDGTWAQLWDRRDTALQAYYDAHPERFRNRPRTKSPS-------
Mvan_0306|M.vanbaalenii_PYR-1 FTPDEVHNGSWTRQWMHRDHILQAYYHAHPERFRARPHTKSPA-------
Mb3460c|M.bovis_AF2122/97 HTPADVHYGRADQIRRHRATVLDTAYRDHLERIRSQTTRATRATGLQRDQ
Rv3430c|M.tuberculosis_H37Rv HTPADVHYGRADQIRRHRATVLDTAYRDHLERIRSQTTRATRATGLQRDQ
MSMEG_1862|M.smegmatis_MC2_155 HTPADVFYGLAGGKDTQRRAVLADARARHPRRFGRDT--APKVIDLP---
MMAR_2548|M.marinum_M LTPTQAEALHYR-HKSSLAAAG----------------------------
MAV_1454|M.avium_104 IPPAEFEAAFYDAYRTDQPLIGIQ--------------------------
TH_4372|M.thermoresistible__bu ISPIDFDLSLDILLSTQV--------------------------------
.* .
Mflv_4078|M.gilvum_PYR-GCK ------PVVGINLPT-----------------ENDPDRLQAA-------
Mvan_0306|M.vanbaalenii_PYR-1 ------AIVGINLPT-----------------EKDPNRLHAA-------
Mb3460c|M.bovis_AF2122/97 PTTEGGPADSINPRKSCLRNVDRFRPGLLDLPAPAPVDLRRLLPSGQIR
Rv3430c|M.tuberculosis_H37Rv PTTEGGPADSINPRKSCLRNVDRFRPGLLDLPAPAPVDLRRLLPSGQIR
MSMEG_1862|M.smegmatis_MC2_155 ------ESAAINPPK----------------PAEQETETEAA-------
MMAR_2548|M.marinum_M -------------------------------------------------
MAV_1454|M.avium_104 -------------------------------------------------
TH_4372|M.thermoresistible__bu -------------------------------------------------