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MIELSRSTWHYRSHPRPRVANPMPHKDRAYPSRIGVADRAVIAEQIIAGWLAGVSVDQSFATMWDAGVLL ASRRSWWRIAAVIDQSLRPVAPTRATNKTPRSAPVLKATGPQQIWSWDITDLHSPWRGVSFKTYSIVDIF SRKIVGWRVEERECDDLAVEMFKTAIAEHGPPAVVHADSGPAMRSTVLKDLLAGLGIGQTHIRPHVSNDN PFSESEFRTMKYRPNYPGVFDDLNTAHAWVQAYVRWYNQHHRHSGIALFTPDEVHNGSWTRQWMHRDHIL QAYYHAHPERFRARPHTKSPAAIVGINLPTEKDPNRLHAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0306 | - | - | 100% (320) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_1094 | - | 3e-08 | 29.01% (162) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_5959 | - | 6e-08 | 29.01% (162) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3460c | - | 9e-45 | 34.68% (297) | transposase |
| M. gilvum PYR-GCK | Mflv_4078 | - | 1e-152 | 78.19% (321) | integrase catalytic subunit |
| M. tuberculosis H37Rv | Rv3430c | - | 2e-45 | 35.02% (297) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 4e-06 | 26.76% (213) | transposase |
| M. marinum M | MMAR_4846 | - | 1e-07 | 26.52% (181) | transposase, ISMyma01_aa2 |
| M. avium 104 | MAV_1454 | - | 3e-09 | 27.61% (163) | transposase |
| M. smegmatis MC2 155 | MSMEG_1862 | - | 5e-47 | 37.37% (289) | transposase |
| M. thermoresistible (build 8) | TH_3317 | - | 2e-08 | 24.07% (270) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1454|M.avium_104 -----------------------------MALSTYYDTKA-------RVP
TH_3317|M.thermoresistible__bu -MIAFIDAHRDQFGVELICRVLRAAIAGFLTSRGYRAAKA-------RPP
Mvan_0306|M.vanbaalenii_PYR-1 -------------------------MIELSRSTWHYRSHP-----RPRVA
Mflv_4078|M.gilvum_PYR-GCK ------------MTAAIGSQRQALAMIDLSRSTWHYRTNP-----RPPVS
Mb3460c|M.bovis_AF2122/97 MIDTAIEEMIPLIGVRAACAATGRAPASYYRAHSKRLSAQSDTFTSTAVT
Rv3430c|M.tuberculosis_H37Rv MIDTAIEEMIPLIGVRAACAATGRAPASYYRAHSKRLSAQSDTFTSTAVT
MSMEG_1862|M.smegmatis_MC2_155 -MDAYNDLRDIQIPTRKAAEVTG-----MHRSTATRRAKP-----APAPA
MAB_2088|M.abscessus_ATCC_1997 ---------------------MTRRVLKLARQPYYRWRAN--------PI
MMAR_4846|M.marinum_M --------------------MLGVSERFACRVTGQHRATQR------HEP
MAV_1454|M.avium_104 SARALRDAVLGPALCQLWKDNYCVYG-ARKLWKTARREGHDVGRDQVARL
TH_3317|M.thermoresistible__bu SERAMRDELLIAELRTVHEQNFSVYG-VKKMHHAMKRRGWRVGREQTRRL
Mvan_0306|M.vanbaalenii_PYR-1 NPMPHKDRAYPSRIGVADRAVIAEQIIAGWLAGVSVDQSFATMWDAGVLL
Mflv_4078|M.gilvum_PYR-GCK DPLPQKHRAYPSRIDEADRAVIRDKILAGWEAGSSVDHAFAASWDEGVML
Mb3460c|M.bovis_AF2122/97 DPSGPRESAQPRALSAAEREHVLAVLNSQRFADMAPAVVYATLLDEGIYL
Rv3430c|M.tuberculosis_H37Rv DPSGPRESAQPRALSAAEREHVLAVLNSQRFADMAPAVVYATLLDEGIYL
MSMEG_1862|M.smegmatis_MC2_155 DR-APR-PVPVNKLTESECARVVEVLNSARFVDAAPMQVWATLLDEGSYL
MAB_2088|M.abscessus_ATCC_1997 TDAELVEAYRANALFDAHGE--DPEFGYRYLVEEAREAGEPMAERTAWRI
MMAR_4846|M.marinum_M VAGTPADPDAALREWLRDYANKHPRRGFRPAYHDARGEGWEVNHKKVQRL
:
MAV_1454|M.avium_104 MRAAGIEGVRRGKRVRTTKP--DPAAARHPDLVKRNFTATAPNQLWVTDL
TH_3317|M.thermoresistible__bu MRKAGLRGVQRGKPVFTTIS--DPAHCRPADLVNRQFSAEAPDRLWVADI
Mvan_0306|M.vanbaalenii_PYR-1 ASRRSWWRIAAVI-DQSLRPVAPTRATNKTPRSAPVLKATGPQQIWSWDI
Mflv_4078|M.gilvum_PYR-GCK ASRRSWWRIAAAIEDQSARPVAPTRSTSKTPRQAPVLKATGPQQIWSWDI
Mb3460c|M.bovis_AF2122/97 CSESTMYRLLRERGQTGDR----RRQATHPAAVKPELVAHQPNSVWSWDI
Rv3430c|M.tuberculosis_H37Rv CSESTMYRLLRERGQTGDR----RRQATHPAAVKPELVAHQPNSVWSWDI
MSMEG_1862|M.smegmatis_MC2_155 CSVSTMYRVLNANKLVKER----RRLARHRKAVCPELVATAPRQVYSWDI
MAB_2088|M.abscessus_ATCC_1997 CSQQQLWSVFGKKRGKNGK----PGPPVHDDLVQRDFTAETPNMLWLSDI
MMAR_4846|M.marinum_M WREEGLRVPQRRKRKRHGTS-----------TAPPEVVADAPDRVWAVDF
. * * :: *:
MAV_1454|M.avium_104 TFVP-TWAGVAYVCF-IIDAYSRMIVGWRVASHMRTS-MVLDALEMARWS
TH_3317|M.thermoresistible__bu TFVR-TWQGFCYTAF-VTDACTKAIKGWAVAASMRTEDLPLEAFNHAVWH
Mvan_0306|M.vanbaalenii_PYR-1 TDLHSPWRGVSFKTYSIVDIFSRKIVGWRVEE-RECDDLAVEMFKTAIAE
Mflv_4078|M.gilvum_PYR-GCK TDLRSPWRGVAFKAYSILDIYSRKIVGWRVEE-RECDDLAVDMFEAAFAG
Mb3460c|M.bovis_AF2122/97 TKLRGPAKWSYYYLYVILDIFSRYVVGWMVAS-RESKVLAERLIAQTLAA
Rv3430c|M.tuberculosis_H37Rv TKLRGPAKWSYYYLYVILDIFSRYVVGWMVAS-RESKVLAERLIAQTLAA
MSMEG_1862|M.smegmatis_MC2_155 TKLAGPVKGVYYDAYVMIDIYSRYIVGVHVHA-RECGQLAKEMMEQIFGT
MAB_2088|M.abscessus_ATCC_1997 TEHY-TGDGKLYLCA-IKDAFSNRIVGYSIDS-RMKSRLATAALRNAVGR
MMAR_4846|M.marinum_M QFDV-TTDGRPIKIVSIIDEHTRECLGGMVERSITGDHLTEELGRIAAGR
. : * :. * : :
MAV_1454|M.avium_104 RGNMLPGLRCHSDAGSQFTSIRYGERLAEIGAVPSIGTVGDSFDNALAET
TH_3317|M.thermoresistible__bu SDSDLSELIHHSDRGSQYLSLTYTDRLAELGIAPSVGSRGDSYDNALAEA
Mvan_0306|M.vanbaalenii_PYR-1 HGPPA---VVHADSGPAMRSTVLKDLLAGLGIGQTHIRPHVSNDNPFSES
Mflv_4078|M.gilvum_PYR-GCK HGLPA---VVHADSGPAMRSTVLKDLLAGLKIGQTHNRPRVSNDNPFSES
Mb3460c|M.bovis_AF2122/97 QHISADQLTLHADRGSSMSSKPVALLLADLGVTKSHSHPHTSNDNPLSEA
Rv3430c|M.tuberculosis_H37Rv QHISADQLTLHADRGSSMSSKPVALLLADLGVTKSHSRPHTSNDNPLSEA
MSMEG_1862|M.smegmatis_MC2_155 YGIPH---VVHADRGTSMTSNTVAGLLSDLGVIRSHSRPKVSNDNPYSES
MAB_2088|M.abscessus_ATCC_1997 RGVVAG-CVVHTDRGSQFRSRKFVQALHHHGMVGSMGRVGAAGDNAAMES
MMAR_4846|M.marinum_M GALPA---VLRCDNGPELACSAMADWAEGQ-VGLHFIPPGEPWRNGYVES
: * *. . . * *:
MAV_1454|M.avium_104 VNGYYKAELIYGPARTGPWKTVEDVELATLSWVY-WHNTSRLHSYLGDIP
TH_3317|M.thermoresistible__bu VNAAYKTELIN---RGKPWRSVDDVELATAGWVA-WYNQERLHEALGYVP
Mvan_0306|M.vanbaalenii_PYR-1 E----FRTMKYRPNYPGVFDDLNTAHAWVQAYVR-WYNQHHRHSGIALFT
Mflv_4078|M.gilvum_PYR-GCK E----FRTMKYRPNYPGVFTDLDSARAWVSAYVS-WYNQHHRHSGVELFT
Mb3460c|M.bovis_AF2122/97 Q----FKTLKYRPDFPKRFESIEAARVHCDRFFG-WYNHEHKHSGIGLHT
Rv3430c|M.tuberculosis_H37Rv Q----FKTLKYRPDFPKRFESIEAARVHCDRFFG-WYNHEHKHSGIGLHT
MSMEG_1862|M.smegmatis_MC2_155 W----FKTLKYAPAFPERFESIHHARDFMDRFVQ-WYNHEHRHSGIGLHT
MAB_2088|M.abscessus_ATCC_1997 F----FSLLQKNVLDRRRWATREELRIAIVTWIERTYHRRRRQGALGRLT
MMAR_4846|M.marinum_M FN----SRIRDECLNINSFWSLAQARVVIGDWKH-EYNHHRRHSSLGYLP
: : . : :: : : : .
MAV_1454|M.avium_104 PAEFEAAFY-DAYRTDQPLIGIQ---------------------------
TH_3317|M.thermoresistible__bu PAEYEAALTGTSHPASQPTPALATN-------------------------
Mvan_0306|M.vanbaalenii_PYR-1 PDEVHNGSWTRQWMHRDHILQAYYHAHPERFRARPHTKSPA---------
Mflv_4078|M.gilvum_PYR-GCK PDSVHDGTWAQLWDRRDTALQAYYDAHPERFRNRPRTKSPS---------
Mb3460c|M.bovis_AF2122/97 PADVHYGRADQIRRHRATVLDTAYRDHLERIRSQTTRATRATGLQRDQPT
Rv3430c|M.tuberculosis_H37Rv PADVHYGRADQIRRHRATVLDTAYRDHLERIRSQTTRATRATGLQRDQPT
MSMEG_1862|M.smegmatis_MC2_155 PADVFYGLAGGKDTQRRAVLADARARHPRRFGRDT--APKVIDLP-----
MAB_2088|M.abscessus_ATCC_1997 PVEYEAIMTTTASQAA----------------------------------
MMAR_4846|M.marinum_M PARYAAACTHR---------------------------------------
*
MAV_1454|M.avium_104 -----------------------------------------------
TH_3317|M.thermoresistible__bu -----------------------------------------------
Mvan_0306|M.vanbaalenii_PYR-1 ----AIVGINLPT-----------------EKDPNRLHAA-------
Mflv_4078|M.gilvum_PYR-GCK ----PVVGINLPT-----------------ENDPDRLQAA-------
Mb3460c|M.bovis_AF2122/97 TEGGPADSINPRKSCLRNVDRFRPGLLDLPAPAPVDLRRLLPSGQIR
Rv3430c|M.tuberculosis_H37Rv TEGGPADSINPRKSCLRNVDRFRPGLLDLPAPAPVDLRRLLPSGQIR
MSMEG_1862|M.smegmatis_MC2_155 ----ESAAINPPK----------------PAEQETETEAA-------
MAB_2088|M.abscessus_ATCC_1997 -----------------------------------------------
MMAR_4846|M.marinum_M -----------------------------------------------