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TILILTDNVHAHALAVDLQARHGDMDVYQSPIGQLPGVPRCDVAERVAEIVERYDLVLSFHCKQRFPAAL IDGVRCVNVHPGFNPYNRGWFPQVFSIIDGQKVGVTIHEIDDQLDHGPIIAQRECAIESWDSSGSVYARL MDIERELVLEHFDAIRDGSYTAKSPATEGNLNLKKDFEQLRRLDLNERGTFGHFLNRLRALTHDDFRNAW FVDASGRKVFVRVVLEPEKPAEA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3404c | - | - | 100% (234) | hypothetical protein Rv3404c |
| M. tuberculosis H37Rv | Rv0956 | purN | 2e-05 | 26.32% (133) | phosphoribosylglycinamide formyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3438c | - | 1e-137 | 100.00% (234) | hypothetical protein Mb3438c |
| M. gilvum PYR-GCK | Mflv_1874 | purN | 4e-06 | 25.32% (154) | phosphoribosylglycinamide formyltransferase |
| M. leprae Br4923 | MLBr_00160 | purN | 1e-07 | 32.95% (88) | phosphoribosylglycinamide formyltransferase |
| M. abscessus ATCC 19977 | MAB_1063 | purN | 5e-08 | 27.08% (144) | phosphoribosylglycinamide formyltransferase |
| M. marinum M | MMAR_4543 | purN | 3e-07 | 31.82% (88) | 5'-phosphoribosylglycinamide formyltransferase PurN |
| M. avium 104 | MAV_1080 | purN | 2e-06 | 31.82% (88) | phosphoribosylglycinamide formyltransferase |
| M. smegmatis MC2 155 | MSMEG_0014 | - | 4e-09 | 30.16% (126) | Formyl transferase |
| M. thermoresistible (build 8) | TH_1361 | purN | 4e-07 | 32.56% (86) | PROBABLE 5'-PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE PURN |
| M. ulcerans Agy99 | MUL_4713 | purN | 3e-07 | 31.82% (88) | phosphoribosylglycinamide formyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4857 | purN | 2e-07 | 27.56% (156) | phosphoribosylglycinamide formyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4543|M.marinum_M -------MQEP---------VRVPPSAPARLVVLASGTGSLLNSLLDAAV
MUL_4713|M.ulcerans_Agy99 -------MQEP---------VRVPPSAPARLVVLASGTGSLLNSLLDAAV
MLBr_00160|M.leprae_Br4923 -------MQEP---------LCVSPSAPSRVVVLASGTGSLLGSLIDASV
MAV_1080|M.avium_104 -------MVEP---------LHVPPNAPARVVVLASGTGSLLSSLIDAAV
Mflv_1874|M.gilvum_PYR-GCK -------MQSEAGGGEQQFHLRVPPSAPARVVVLASGAGSLLASLLSSAV
Mvan_4857|M.vanbaalenii_PYR-1 -------MQPEAGGREERCVLRVPPSAPARLVVLASGTGSLLASLLKSAV
TH_1361|M.thermoresistible__bu ----------------------VPPSAPARVVVLASGTGSLLAALLEAAV
MAB_1063|M.abscessus_ATCC_1997 -------MSVPSQS------VEIAPSAPARVVVLASGTGTLLRSLLDAAT
Rv3404c|M.tuberculosis_H37Rv -----------------MTILILTDNVHAHALAVDLQARHGDMDVYQSPI
Mb3438c|M.bovis_AF2122/97 -----------------MTILILTDNVHAHALAVDLQARHGDMDVYQSPI
MSMEG_0014|M.smegmatis_MC2_155 MFPVRVVMFGYQTWGHRTLQALLKSRHEVCLVVTHPTSDHAYESIWADSV
: :. : : .
MMAR_4543|M.marinum_M ADYP-------ARIVAVGVDRDCRATEIAAQASVPAFTVR----VSDHPS
MUL_4713|M.ulcerans_Agy99 ADYP-------ARIVAVGVDRDCRATEVAAQASVPAFTVR----VSDHPS
MLBr_00160|M.leprae_Br4923 GNYP-------ARVVAVGVDRDCGATKIAKAASVPTFTVR----LADPPG
MAV_1080|M.avium_104 GDYP-------ARVVAVGADRDCLATQIAAAASLPSFTVR----LGDHPD
Mflv_1874|M.gilvum_PYR-GCK GDFP-------ARVVAVGTDRPCAALDIAAKADVPTFTVA----LTDHPD
Mvan_4857|M.vanbaalenii_PYR-1 GDYP-------ARVVAVGTDRVCAALDIASGAAIPTFTVP----LSEYPD
TH_1361|M.thermoresistible__bu GDYP-------ARVVAVGTDRDCAALEIAAAANVPTFTVR----LRDYPD
MAB_1063|M.abscessus_ATCC_1997 GDFP-------ARIVAVGTDRPCPALDIAADAQLPSYMVR----LGDYDS
Rv3404c|M.tuberculosis_H37Rv GQLPGVPRCDVAERVAEIVERYDLVLSFHCKQRFPAALIDGVRCVNVHPG
Mb3438c|M.bovis_AF2122/97 GQLPGVPRCDVAERVAEIVERYDLVLSFHCKQRFPAALIDGVRCVNVHPG
MSMEG_0014|M.smegmatis_MC2_155 EDLARG-----AGIEVLLAKRPTPELVERVRELAPDVGVAN--NWRTRLP
: . * . ..* * :
MMAR_4543|M.marinum_M RDAWDAAITAAAAAHSPDLVVSAGFMRILG------------PQFLSKFH
MUL_4713|M.ulcerans_Agy99 RDAWNAAITAATAAHSPDLVVSAGFMRILG------------PQFLSKFH
MLBr_00160|M.leprae_Br4923 RDAWDAKITEAVASYKPDLVVLAGFMRILG------------PQFLARFF
MAV_1080|M.avium_104 RAAWDAAITEATAAHSPDLVVSAGFMKILG------------PQFLSRFY
Mflv_1874|M.gilvum_PYR-GCK RTAWDAAITEATAAHAPDIVVAAGFMKILG------------AGFLSRFP
Mvan_4857|M.vanbaalenii_PYR-1 RAAWDAALADATAAHRPDLVVSAGFMKILG------------PQFLSTFP
TH_1361|M.thermoresistible__bu RQAWDAAITEAVAAHQPDLVVSAGFMKILG------------PHFLSRFQ
MAB_1063|M.abscessus_ATCC_1997 REQWDAAIAEATAVHRPDLVVSAGFMKILG------------PQFLSQFL
Rv3404c|M.tuberculosis_H37Rv FNPYNRGWFPQVFSIIDGQKVGVTIHEIDD------------QLDHGPII
Mb3438c|M.bovis_AF2122/97 FNPYNRGWFPQVFSIIDGQKVGVTIHEIDD------------QLDHGPII
MSMEG_0014|M.smegmatis_MC2_155 RELFSIPKYGTVNLHDSLLPKFTGFSPVIWSLISGAGQTGLTAHFMDDEL
:. . . : :
MMAR_4543|M.marinum_M QR---ILNTHPALLPAFPGAHGVADALAYG-VKVTGCTVHLVDAGMDTGP
MUL_4713|M.ulcerans_Agy99 QR---ILNTHPALLPAFPGAHGVADALAYG-VKVTGCTVHLVDAGMDTGP
MLBr_00160|M.leprae_Br4923 GR---IVNTHPALLPAFPGTHGVADALAYG-VKVTGATVHLVDAGTDTGP
MAV_1080|M.avium_104 GR---VINTHPALLPAFPGAHGVAEALAYG-VKVTGCTVHLVDAGTDTGP
Mflv_1874|M.gilvum_PYR-GCK GR---VLNSHPALLPAFPGAHAVRDALAYG-VRVTGCTVHLVDAGTDTGP
Mvan_4857|M.vanbaalenii_PYR-1 GR---VLNTHPALLPAFPGAHAVRDALAYG-VRVTGCTVHLVDAGTDTGP
TH_1361|M.thermoresistible__bu GR---VLNTHPALLPAFPGAHAVADALSYG-VQVTGCTVHLVDAGTDTGP
MAB_1063|M.abscessus_ATCC_1997 GR---VINTHPALLPSFPGAHAVPEALAHG-VKITGCTVHLVDAGMDTGP
Rv3404c|M.tuberculosis_H37Rv AQRECAIESWDSSGSVYARLMDIERELVLEHFDAIRDGSYTAKSPATEGN
Mb3438c|M.bovis_AF2122/97 AQRECAIESWDSSGSVYARLMDIERELVLEHFDAIRDGSYTAKSPATEGN
MSMEG_0014|M.smegmatis_MC2_155 DTGDILLQRSVEITPTSTGTSLVYDTLDLIPDVLEDALDAIENGTATPVP
:: . . : * ..
MMAR_4543|M.marinum_M ILAQQAIAVLDGDDEAT-----------------------------LHER
MUL_4713|M.ulcerans_Agy99 ILAQQAIAVLDGDDEAT-----------------------------LHER
MLBr_00160|M.leprae_Br4923 ILAQQSVPVLDGDDTAA-----------------------------LHER
MAV_1080|M.avium_104 ILAQQSVPVLDGDDEQT-----------------------------LHER
Mflv_1874|M.gilvum_PYR-GCK IVAQQAVAVYDDDDESA-----------------------------LHER
Mvan_4857|M.vanbaalenii_PYR-1 IVAQQAVTVLDGDDESS-----------------------------LHER
TH_1361|M.thermoresistible__bu IIAQRAVPVLKGDDEAT-----------------------------LHER
MAB_1063|M.abscessus_ATCC_1997 ILAQQAVPVDRDDDEAS-----------------------------LHER
Rv3404c|M.tuberculosis_H37Rv LNLKKDFEQLRRLDLNERGTFGH-----------------------FLNR
Mb3438c|M.bovis_AF2122/97 LNLKKDFEQLRRLDLNERGTFGH-----------------------FLNR
MSMEG_0014|M.smegmatis_MC2_155 QDLSQRTFFHKRSDRDSLVDWSWPAADIERFIRALSDPYPNAYTYFRGER
.: * :*
MMAR_4543|M.marinum_M IKVVERKLLVDVVAGIAT--------GGVTVIGRKAMIGRKATIG-----
MUL_4713|M.ulcerans_Agy99 IKVVERKLLVDVVAGIAA--------GGVTVIGRKAMIGRKATIG-----
MLBr_00160|M.leprae_Br4923 IKVIERRLLVDVVAVIAT--------GGVTLVGRKATIGRKATIE-----
MAV_1080|M.avium_104 IKVTERKLLVDVVAAIAT--------GGLTLVGRKATIG-----------
Mflv_1874|M.gilvum_PYR-GCK IKVIERRLLVDVVAAVAS--------RGVTWTGRKATLG-----------
Mvan_4857|M.vanbaalenii_PYR-1 IKVIERQLLVDVVAAMAT--------RGMTWTGRKVNLG-----------
TH_1361|M.thermoresistible__bu IKVVERQLLVEVLAALAT--------RGVTWSGRKATIG-----------
MAB_1063|M.abscessus_ATCC_1997 IKVVERTLLVDVLAAVAT--------KGLTWNGRRASIK-----------
Rv3404c|M.tuberculosis_H37Rv LRALTHDDFRNAWFVDAS--------GRKVFVRVVLEPEKPAEA------
Mb3438c|M.bovis_AF2122/97 LRALTHDDFRNAWFVDAS--------GRKVFVRVVLEPEKPAEA------
MSMEG_0014|M.smegmatis_MC2_155 LRLISAHVSRCTYGGTPGRVFIEENGGMVIVAGADAFRGRSPGLVLDVVR
:: . .
MMAR_4543|M.marinum_M -----------------------------
MUL_4713|M.ulcerans_Agy99 -----------------------------
MLBr_00160|M.leprae_Br4923 -----------------------------
MAV_1080|M.avium_104 -----------------------------
Mflv_1874|M.gilvum_PYR-GCK -----------------------------
Mvan_4857|M.vanbaalenii_PYR-1 -----------------------------
TH_1361|M.thermoresistible__bu -----------------------------
MAB_1063|M.abscessus_ATCC_1997 -----------------------------
Rv3404c|M.tuberculosis_H37Rv -----------------------------
Mb3438c|M.bovis_AF2122/97 -----------------------------
MSMEG_0014|M.smegmatis_MC2_155 TDDGIDHSALDYFGHGGGYLTATPEFATV