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QPEAGGREERCVLRVPPSAPARLVVLASGTGSLLASLLKSAVGDYPARVVAVGTDRVCAALDIASGAAIP TFTVPLSEYPDRAAWDAALADATAAHRPDLVVSAGFMKILGPQFLSTFPGRVLNTHPALLPAFPGAHAVR DALAYGVRVTGCTVHLVDAGTDTGPIVAQQAVTVLDGDDESSLHERIKVIERQLLVDVVAAMATRGMTWT GRKVNLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4857 | purN | - | 100% (218) | phosphoribosylglycinamide formyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1265 | purU | 6e-13 | 32.47% (194) | formyltetrahydrofolate deformylase |
| M. vanbaalenii PYR-1 | Mvan_2687 | fmt | 6e-08 | 32.35% (102) | methionyl-tRNA formyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0981 | purN | 2e-84 | 75.12% (205) | phosphoribosylglycinamide formyltransferase |
| M. gilvum PYR-GCK | Mflv_1874 | purN | 4e-99 | 81.65% (218) | phosphoribosylglycinamide formyltransferase |
| M. tuberculosis H37Rv | Rv0956 | purN | 2e-84 | 75.12% (205) | phosphoribosylglycinamide formyltransferase |
| M. leprae Br4923 | MLBr_00160 | purN | 3e-80 | 70.24% (205) | phosphoribosylglycinamide formyltransferase |
| M. abscessus ATCC 19977 | MAB_1063 | purN | 3e-83 | 71.57% (204) | phosphoribosylglycinamide formyltransferase |
| M. marinum M | MMAR_4543 | purN | 5e-85 | 74.63% (205) | 5'-phosphoribosylglycinamide formyltransferase PurN |
| M. avium 104 | MAV_1080 | purN | 7e-89 | 77.07% (205) | phosphoribosylglycinamide formyltransferase |
| M. smegmatis MC2 155 | MSMEG_5516 | purN | 5e-88 | 76.85% (203) | phosphoribosylglycinamide formyltransferase |
| M. thermoresistible (build 8) | TH_1361 | purN | 2e-93 | 80.30% (203) | PROBABLE 5'-PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE PURN |
| M. ulcerans Agy99 | MUL_4713 | purN | 2e-84 | 73.66% (205) | phosphoribosylglycinamide formyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4857|M.vanbaalenii_PYR-1 MQPEAGGREERCVLRVPPSAPARLVVLASGTGSLLASLLKSAVGDYPARV
Mflv_1874|M.gilvum_PYR-GCK MQSEAGGGEQQFHLRVPPSAPARVVVLASGAGSLLASLLSSAVGDFPARV
MSMEG_5516|M.smegmatis_MC2_155 ---------------MPPSAPARLVVLASGAGSLLASLLEAATGEYPARV
Mb0981|M.bovis_AF2122/97 ---------MQEPLRVPPSAPARLVVLASGTGSLLRSLLDAAVGDYPARV
Rv0956|M.tuberculosis_H37Rv ---------MQEPLRVPPSAPARLVVLASGTGSLLRSLLDAAVGDYPARV
MMAR_4543|M.marinum_M ---------MQEPVRVPPSAPARLVVLASGTGSLLNSLLDAAVADYPARI
MUL_4713|M.ulcerans_Agy99 ---------MQEPVRVPPSAPARLVVLASGTGSLLNSLLDAAVADYPARI
MLBr_00160|M.leprae_Br4923 ---------MQEPLCVSPSAPSRVVVLASGTGSLLGSLIDASVGNYPARV
MAV_1080|M.avium_104 ---------MVEPLHVPPNAPARVVVLASGTGSLLSSLIDAAVGDYPARV
TH_1361|M.thermoresistible__bu ---------------VPPSAPARVVVLASGTGSLLAALLEAAVGDYPARV
MAB_1063|M.abscessus_ATCC_1997 ------MSVPSQSVEIAPSAPARVVVLASGTGTLLRSLLDAATGDFPARI
:.*.**:*:******:*:** :*:.::..::***:
Mvan_4857|M.vanbaalenii_PYR-1 VAVGTDRVCAALDIASGAAIPTFTVPLSEYPDRAAWDAALADATAAHRPD
Mflv_1874|M.gilvum_PYR-GCK VAVGTDRPCAALDIAAKADVPTFTVALTDHPDRTAWDAAITEATAAHAPD
MSMEG_5516|M.smegmatis_MC2_155 VAVGTDRKCAALDVAAAADVPTYTVRLADHADRAAWDAALTAATAEHHPD
Mb0981|M.bovis_AF2122/97 VAVGVDRECRAAEIAAEASVPVFTVRLADHPSRDAWDVAITAATAAHEPD
Rv0956|M.tuberculosis_H37Rv VAVGVDRECRAAEIAAEASVPVFTVRLADHPSRDAWDVAITAATAAHEPD
MMAR_4543|M.marinum_M VAVGVDRDCRATEIAAQASVPAFTVRVSDHPSRDAWDAAITAAAAAHSPD
MUL_4713|M.ulcerans_Agy99 VAVGVDRDCRATEVAAQASVPAFTVRVSDHPSRDAWNAAITAATAAHSPD
MLBr_00160|M.leprae_Br4923 VAVGVDRDCGATKIAKAASVPTFTVRLADPPGRDAWDAKITEAVASYKPD
MAV_1080|M.avium_104 VAVGADRDCLATQIAAAASLPSFTVRLGDHPDRAAWDAAITEATAAHSPD
TH_1361|M.thermoresistible__bu VAVGTDRDCAALEIAAAANVPTFTVRLRDYPDRQAWDAAITEAVAAHQPD
MAB_1063|M.abscessus_ATCC_1997 VAVGTDRPCPALDIAADAQLPSYMVRLGDYDSREQWDAAIAEATAVHRPD
****.** * * .:* * :* : * : : .* *:. :: *.* : **
Mvan_4857|M.vanbaalenii_PYR-1 LVVSAGFMKILGPQFLSTFPGRVLNTHPALLPAFPGAHAVRDALAYGVRV
Mflv_1874|M.gilvum_PYR-GCK IVVAAGFMKILGAGFLSRFPGRVLNSHPALLPAFPGAHAVRDALAYGVRV
MSMEG_5516|M.smegmatis_MC2_155 LVVSAGFMKILGAEFLSRFPGRVVNTHPALLPAFPGAHAVREALNYGVRV
Mb0981|M.bovis_AF2122/97 LVVSAGFMRILGPQFLSRFYGRTLNTHPALLPAFPGTHGVADALAYGVKV
Rv0956|M.tuberculosis_H37Rv LVVSAGFMRILGPQFLSRFYGRTLNTHPALLPAFPGTHGVADALAYGVKV
MMAR_4543|M.marinum_M LVVSAGFMRILGPQFLSKFHQRILNTHPALLPAFPGAHGVADALAYGVKV
MUL_4713|M.ulcerans_Agy99 LVVSAGFMRILGPQFLSKFHQRILNTHPALLPAFPGAHGVADALAYGVKV
MLBr_00160|M.leprae_Br4923 LVVLAGFMRILGPQFLARFFGRIVNTHPALLPAFPGTHGVADALAYGVKV
MAV_1080|M.avium_104 LVVSAGFMKILGPQFLSRFYGRVINTHPALLPAFPGAHGVAEALAYGVKV
TH_1361|M.thermoresistible__bu LVVSAGFMKILGPHFLSRFQGRVLNTHPALLPAFPGAHAVADALSYGVQV
MAB_1063|M.abscessus_ATCC_1997 LVVSAGFMKILGPQFLSQFLGRVINTHPALLPSFPGAHAVPEALAHGVKI
:** ****:***. **: * * :*:******:***:*.* :** :**::
Mvan_4857|M.vanbaalenii_PYR-1 TGCTVHLVDAGTDTGPIVAQQAVTVLDGDDESSLHERIKVIERQLLVDVV
Mflv_1874|M.gilvum_PYR-GCK TGCTVHLVDAGTDTGPIVAQQAVAVYDDDDESALHERIKVIERRLLVDVV
MSMEG_5516|M.smegmatis_MC2_155 TGCTVHLVDSGVDTGPILAQQVVEIDDDDTEETLHERIKVVERRLLVDVL
Mb0981|M.bovis_AF2122/97 TGATVHLVDAGTDTGPILAQQPVPVLDGDDEETLHERIKVTERRLLVAAV
Rv0956|M.tuberculosis_H37Rv TGATVHLVDAGTDTGPILAQQPVPVLDGDDEETLHERIKVTERRLLVAAV
MMAR_4543|M.marinum_M TGCTVHLVDAGMDTGPILAQQAIAVLDGDDEATLHERIKVVERKLLVDVV
MUL_4713|M.ulcerans_Agy99 TGCTVHLVDAGMDTGPILAQQAIAVLDGDDEATLHERIKVVERKLLVDVV
MLBr_00160|M.leprae_Br4923 TGATVHLVDAGTDTGPILAQQSVPVLDGDDTAALHERIKVIERRLLVDVV
MAV_1080|M.avium_104 TGCTVHLVDAGTDTGPILAQQSVPVLDGDDEQTLHERIKVTERKLLVDVV
TH_1361|M.thermoresistible__bu TGCTVHLVDAGTDTGPIIAQRAVPVLKGDDEATLHERIKVVERQLLVEVL
MAB_1063|M.abscessus_ATCC_1997 TGCTVHLVDAGMDTGPILAQQAVPVDRDDDEASLHERIKVVERTLLVDVL
**.******:* *****:**: : : .* :******* ** *** .:
Mvan_4857|M.vanbaalenii_PYR-1 AAMATRGMTWTGRKVNLG------
Mflv_1874|M.gilvum_PYR-GCK AAVASRGVTWTGRKATLG------
MSMEG_5516|M.smegmatis_MC2_155 AALATRGVIWTGRKATFG------
Mb0981|M.bovis_AF2122/97 AALATHGVTVVGRTATMGRKVTIG
Rv0956|M.tuberculosis_H37Rv AALATHGVTVVGRTATMGRKVTIG
MMAR_4543|M.marinum_M AGIATGGVTVIGRKAMIGRKATIG
MUL_4713|M.ulcerans_Agy99 AGIAAGGVTVIGRKAMIGRKATIG
MLBr_00160|M.leprae_Br4923 AVIATGGVTLVGRKATIGRKATIE
MAV_1080|M.avium_104 AAIATGGLTLVGRKATIG------
TH_1361|M.thermoresistible__bu AALATRGVTWSGRKATIG------
MAB_1063|M.abscessus_ATCC_1997 AAVATKGLTWNGRRASIK------
* :*: *: ** . :