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M. smegmatis MC2 155 MSMEG_0014 (-)

annotation: Formyl transferase
coordinates: 14130 - 15098
length: 322

FPVRVVMFGYQTWGHRTLQALLKSRHEVCLVVTHPTSDHAYESIWADSVEDLARGAGIEVLLAKRPTPEL
VERVRELAPDVGVANNWRTRLPRELFSIPKYGTVNLHDSLLPKFTGFSPVIWSLISGAGQTGLTAHFMDD
ELDTGDILLQRSVEITPTSTGTSLVYDTLDLIPDVLEDALDAIENGTATPVPQDLSQRTFFHKRSDRDSL
VDWSWPAADIERFIRALSDPYPNAYTYFRGERLRLISAHVSRCTYGGTPGRVFIEENGGMVIVAGADAFR
GRSPGLVLDVVRTDDGIDHSALDYFGHGGGYLTATPEFATV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0014--100% (322)Formyl transferase
M. smegmatis MC2 155MSMEG_3064fmt2e-2230.26% (271) methionyl-tRNA formyltransferase
M. smegmatis MC2 155MSMEG_5516purN2e-0736.84% (95) phosphoribosylglycinamide formyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1441fmt2e-2031.73% (271) methionyl-tRNA formyltransferase
M. gilvum PYR-GCKMflv_3730fmt5e-2434.60% (237) methionyl-tRNA formyltransferase
M. tuberculosis H37RvRv1406fmt2e-2031.73% (271) methionyl-tRNA formyltransferase
M. leprae Br4923MLBr_00552fmt2e-1932.26% (248) methionyl-tRNA formyltransferase
M. abscessus ATCC 19977MAB_2260-1e-9755.05% (307) putative formyltransferase
M. marinum MMMAR_2215fmt3e-2033.47% (248) methionyl-tRNA formyltransferase Fmt
M. avium 104MAV_3372fmt3e-2434.94% (249) methionyl-tRNA formyltransferase
M. thermoresistible (build 8)TH_1529fmt3e-2532.71% (269) PROBABLE METHIONYL-TRNA FORMYLTRANSFERASE FMT
M. ulcerans Agy99MUL_1802fmt9e-2133.47% (248) methionyl-tRNA formyltransferase
M. vanbaalenii PYR-1Mvan_2687fmt1e-2232.52% (246) methionyl-tRNA formyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1441|M.bovis_AF2122/97            ---MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPS
Rv1406|M.tuberculosis_H37Rv         ---MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPS
MLBr_00552|M.leprae_Br4923          -MLVRLVFAGTPESALPALCRLIDSPRHDVIAVLTRPDAASGRRGKPEPS
MAV_3372|M.avium_104                -MPVRLVFAGTPEPALPALRRLLDSPRHEVIAVLTRPDAASGRRGKPEPS
MMAR_2215|M.marinum_M               ---MRLVFAGTPETALPALHQLIDSPRHDVIAVLTRPDAASGRRGKPEPS
MUL_1802|M.ulcerans_Agy99           ---MRLVFAGTPETALPALHQLIDSPRHDVIAVLTRPDAASGRRGKPEPS
Mflv_3730|M.gilvum_PYR-GCK          ---MRLVFAGTPEPALPSLQRLIDSARHDVIAVLTRPDAAAGRRGRPSPS
Mvan_2687|M.vanbaalenii_PYR-1       ---MRLVFAGTPEPALPSLQRLIDSDRHEVIAVMTRPDAVAGRRGRPSPS
TH_1529|M.thermoresistible__bu      ---MRLVFAGTPEAALPSLRRLIDXXRHEVVAVLTRPDAAAGRRARPAPS
MSMEG_0014|M.smegmatis_MC2_155      MFPVRVVMFGYQTWGHRTLQALLKSR-HEVCLVVTHPTSDHAYES-IWAD
MAB_2260|M.abscessus_ATCC_1997      ---MRVVFFGYQTWGYRTLQALIDLG-HEIVLAVTHPMSEDAYKA-IWAA
                                       :*:*: *    .  :*  *:.   *::  .:*:* :  . ..   . 

Mb1441|M.bovis_AF2122/97            PVAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLL
Rv1406|M.tuberculosis_H37Rv         PVAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLL
MLBr_00552|M.leprae_Br4923          PVAREALDRGIPLLRPARPNSPVFVSELSEWAPECCVVVAYGALLGSPLL
MAV_3372|M.avium_104                PVAREALDRGIPVLRPARPNSPEFVAELAQLAPDCCAVVAYGALLRDELL
MMAR_2215|M.marinum_M               PVARAALERDIPVLRPSRPNSAEFVAELSELAPQCCAVVAYGALLGDALL
MUL_1802|M.ulcerans_Agy99           PVARAALERGIPVLRPSRPNSAEFVAELSELAPQCCAVVAYGALLGDALL
Mflv_3730|M.gilvum_PYR-GCK          PVAELAAAHGIPVLKPPRPNSEEFVAELAALAPDCCAVVAYGALLREELL
Mvan_2687|M.vanbaalenii_PYR-1       PVAQLAAAHGIPVLKPARPNSGEFVAELSALSPDCCAVVAYGALLGDALL
TH_1529|M.thermoresistible__bu      PVAKLASEHGIPVLRPPSPNTDEFIAELTELAPDCCPVVAYGALLSERLL
MSMEG_0014|M.smegmatis_MC2_155      SVEDLARGAGIEVLLAKRPT-PELVERVRELAPDVGVANNWRTRLPRELF
MAB_2260|M.abscessus_ATCC_1997      PVEELAREHGIPAHFTKRVD-AETIDLVRSVDPDVIVVNSWYNRMPVELY
                                    .*   *   .*    .        :  :    *:   .  :   :   * 

Mb1441|M.bovis_AF2122/97            AVPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGP
Rv1406|M.tuberculosis_H37Rv         AVPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGP
MLBr_00552|M.leprae_Br4923          AVPPRGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGP
MAV_3372|M.avium_104                AVPPHGWINLHFSLLPAWRGAAPVQAAIAAGDTITGATTFRIEPALDSGP
MMAR_2215|M.marinum_M               GVPPQGWVNLHFSLLPAWRGAAPVQAAIAAGDAVTGATTFQIEPSLDSGP
MUL_1802|M.ulcerans_Agy99           GVPPQGWVNLHFSLLPAWRGAAPVQAAIAAGDAVTGATTFQIEPSLDSGP
Mflv_3730|M.gilvum_PYR-GCK          AVPALGWVNLHFSVLPAWRGAAPVQAALAAGDEVTGATTFQIELSLDSGP
Mvan_2687|M.vanbaalenii_PYR-1       AVPAHGWVNLHFSVLPAWRGAAPVQAALAAGDEVTGATTFQIERSLDSGP
TH_1529|M.thermoresistible__bu      AVPRHGWVNLHFSLLPAWRGAAPVQAAIAAGDTVTGASTFRIEPALDSGP
MSMEG_0014|M.smegmatis_MC2_155      SIPKYGTVNLHDSLLPKFTGFSPVIWSLISGAGQTGLTAHFMDDELDTGD
MAB_2260|M.abscessus_ATCC_1997      DLPPYGTLNFHDSLLPKFTGFSPVLWALISGESEFGLTVHRMDSGLDTGD
                                     :*  * :*:* *:** : * :**  :: :*    * :.. ::  **:* 

Mb1441|M.bovis_AF2122/97            IYGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPAD
Rv1406|M.tuberculosis_H37Rv         IYGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPAD
MLBr_00552|M.leprae_Br4923          VYGVVTETIQPTDTAGDLLERLAVSGATLLSSTLDGIADAILTPRQQPVD
MAV_3372|M.avium_104                IYGVVTEAIRPTDTAGELLARLAVSGAELLSATLDGIADSTLTPRPQPAE
MMAR_2215|M.marinum_M               VYGVVTETIRPTDTAGDLLGRLAVSGAELLSATLDGIAEGALTARPQPAD
MUL_1802|M.ulcerans_Agy99           VYGVVTETIRPTDTAGDLLGRLAVSGAELLSATLDGIAEGALTARPQPAD
Mflv_3730|M.gilvum_PYR-GCK          VYGVVTETIRPTDTAGDLLGRLAESGAGLLEATMDGIEDGTLTAVPQPAE
Mvan_2687|M.vanbaalenii_PYR-1       VYGVVTETIRPTDTAGDLLERLSVSGAGLLEATMDGIEDGTLTAVPQPPE
TH_1529|M.thermoresistible__bu      IYGVVTETIRPTDTAGDLLDRLADSGAELLERTLDGIEDGTLTAVPQPSE
MSMEG_0014|M.smegmatis_MC2_155      ILLQRSVEITPTSTGTSLVYDTLDLIPDVLEDALDAIENGTATPVPQDLS
MAB_2260|M.abscessus_ATCC_1997      ILVQRSLPIGPTDTGTELVLRGMELIPRVLAEALNALESGSAAWRPQNKA
                                    :    :  * **.*. .*:       . :*  :::.: .   :   *   

Mb1441|M.bovis_AF2122/97            GVSVAPKITVANARVRWDLPAAVVERRIRAVT-PNPGAWTLIGDLRVKLG
Rv1406|M.tuberculosis_H37Rv         GVSVAPKITVANARVRWDLPAAVVERRIRAVT-PNPGAWTLIGDLRVKLG
MLBr_00552|M.leprae_Br4923          GVSFAPKITVEQARVCWDLPAPVVERRIRAVT-PNPGAWTLVGKLRVKLG
MAV_3372|M.avium_104                GVSIAPKITVEQARVRWDLPAPVVERRIRAVT-PNPGAWTVIGDLRIKLG
MMAR_2215|M.marinum_M               GVTLAPKISVEQARVRWELPAPIIERRIRAVT-PNPGAWTLIGDLRVKLG
MUL_1802|M.ulcerans_Agy99           GVTLAPKISVEQARVRWELPVPIIERRIRAVT-PNPGAWTLIGDLRVKLG
Mflv_3730|M.gilvum_PYR-GCK          GVSIAPKVSVDDARIRWELPAHVVDRRIRSVT-PNPGAWTMAGELRIKVG
Mvan_2687|M.vanbaalenii_PYR-1       GVSVAPKVTVDDARIRWELPAHVVDRRVRSVT-PNPGAWTMIGDQRIKVG
TH_1529|M.thermoresistible__bu      GVSYAPKITVEAARIRWDLPAHVVERRIRAMT-PNPGAWTMIGDLRVKLG
MSMEG_0014|M.smegmatis_MC2_155      QRTFFHKRSDRDSLVDWSWPAADIERFIRALSDPYPNAYTYFRGERLRLI
MAB_2260|M.abscessus_ATCC_1997      ERTFCHKRSEQDSALDWAWPAEDLERFVRALSEPYPRAFAFYNTERIEVL
                                      :   * :   : : *  *.  ::* :*::: * * *::     *:.: 

Mb1441|M.bovis_AF2122/97            PVHLDA----AHRPSKPLPPGGIHVER-----TSVWIGTGSEP-----VR
Rv1406|M.tuberculosis_H37Rv         PVHLDA----AHRPSKPLPPGGIHVER-----TSVWIGTGSEP-----VR
MLBr_00552|M.leprae_Br4923          PVRFDSGAVEVPRLLKPLLPGGIHVDH-----KSVWIGTGSDP-----VR
MAV_3372|M.avium_104                PVRLGAAS-DLPAPPEPLPPGAIHVDR-----KSVWVGTASDP-----VR
MMAR_2215|M.marinum_M               PVYLDA----AVKPPGPLPPGAIQVDR-----KHVWVGTGSEP-----LR
MUL_1802|M.ulcerans_Agy99           PVYLDA----AVEPPGPLPPGAIQVDR-----KHVWVGTGSEP-----LR
Mflv_3730|M.gilvum_PYR-GCK          PVTVPD------DGPKDLEPGEIRVGK-----KHVHVGTATDA-----VL
Mvan_2687|M.vanbaalenii_PYR-1       PVTVAG------DGPKGLEPGEIRVDK-----KHIHVGTGSDA-----VL
TH_1529|M.thermoresistible__bu      PVTVDD-------DAEPLAPGEIRAGRDGSGKQAVWFGTGTHP-----VR
MSMEG_0014|M.smegmatis_MC2_155      SAHVSR-------CTYGGTPGRVFIEE--NGGMVIVAGADAFRGRSPGLV
MAB_2260|M.abscessus_ATCC_1997      EARVSE-------ARYGGTPGRVTVQE--QGG-AVVCGPGAHRAANRGLV
                                     . .               ** :   .       :  *. :       : 

Mb1441|M.bovis_AF2122/97            LGQIQPPGKKLMNAADWARGARLDLAARAT----
Rv1406|M.tuberculosis_H37Rv         LGQIQPPGKKLMNAADWARGARLDLAARAT----
MLBr_00552|M.leprae_Br4923          LSKVQPQGKKFMNAVDWAHGARLDPAARAS----
MAV_3372|M.avium_104                LDQIQPPGKKFMNAVDWARGARLDPAARAT----
MMAR_2215|M.marinum_M               LGQVQPPGKKLMNAADWARGARLDPSVRAS----
MUL_1802|M.ulcerans_Agy99           LGQVQPPGKKLMNAADWARGARLDPSVRAS----
Mflv_3730|M.gilvum_PYR-GCK          LGTVQPPGKKSMNAADWARGARAEDIRRAR----
Mvan_2687|M.vanbaalenii_PYR-1       LGTVQPPGKKPMNAADWARGARLDENGWAR----
TH_1529|M.thermoresistible__bu      LGWIQPPGKKPMNAPDWARGARLDDTARAR----
MSMEG_0014|M.smegmatis_MC2_155      LDVVRTDDGIDHSALDYFGHGGGYLTATPEFATV
MAB_2260|M.abscessus_ATCC_1997      ITRIRRADGSEVSGEEYFRRGG-YLDGGN-----
                                    :  ::  .    .. ::   .