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FPVRVVMFGYQTWGHRTLQALLKSRHEVCLVVTHPTSDHAYESIWADSVEDLARGAGIEVLLAKRPTPEL VERVRELAPDVGVANNWRTRLPRELFSIPKYGTVNLHDSLLPKFTGFSPVIWSLISGAGQTGLTAHFMDD ELDTGDILLQRSVEITPTSTGTSLVYDTLDLIPDVLEDALDAIENGTATPVPQDLSQRTFFHKRSDRDSL VDWSWPAADIERFIRALSDPYPNAYTYFRGERLRLISAHVSRCTYGGTPGRVFIEENGGMVIVAGADAFR GRSPGLVLDVVRTDDGIDHSALDYFGHGGGYLTATPEFATV*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_0014 | - | - | 100% (322) | Formyl transferase |
M. smegmatis MC2 155 | MSMEG_3064 | fmt | 2e-22 | 30.26% (271) | methionyl-tRNA formyltransferase |
M. smegmatis MC2 155 | MSMEG_5516 | purN | 2e-07 | 36.84% (95) | phosphoribosylglycinamide formyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1441 | fmt | 2e-20 | 31.73% (271) | methionyl-tRNA formyltransferase |
M. gilvum PYR-GCK | Mflv_3730 | fmt | 5e-24 | 34.60% (237) | methionyl-tRNA formyltransferase |
M. tuberculosis H37Rv | Rv1406 | fmt | 2e-20 | 31.73% (271) | methionyl-tRNA formyltransferase |
M. leprae Br4923 | MLBr_00552 | fmt | 2e-19 | 32.26% (248) | methionyl-tRNA formyltransferase |
M. abscessus ATCC 19977 | MAB_2260 | - | 1e-97 | 55.05% (307) | putative formyltransferase |
M. marinum M | MMAR_2215 | fmt | 3e-20 | 33.47% (248) | methionyl-tRNA formyltransferase Fmt |
M. avium 104 | MAV_3372 | fmt | 3e-24 | 34.94% (249) | methionyl-tRNA formyltransferase |
M. thermoresistible (build 8) | TH_1529 | fmt | 3e-25 | 32.71% (269) | PROBABLE METHIONYL-TRNA FORMYLTRANSFERASE FMT |
M. ulcerans Agy99 | MUL_1802 | fmt | 9e-21 | 33.47% (248) | methionyl-tRNA formyltransferase |
M. vanbaalenii PYR-1 | Mvan_2687 | fmt | 1e-22 | 32.52% (246) | methionyl-tRNA formyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb1441|M.bovis_AF2122/97 ---MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPS Rv1406|M.tuberculosis_H37Rv ---MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPS MLBr_00552|M.leprae_Br4923 -MLVRLVFAGTPESALPALCRLIDSPRHDVIAVLTRPDAASGRRGKPEPS MAV_3372|M.avium_104 -MPVRLVFAGTPEPALPALRRLLDSPRHEVIAVLTRPDAASGRRGKPEPS MMAR_2215|M.marinum_M ---MRLVFAGTPETALPALHQLIDSPRHDVIAVLTRPDAASGRRGKPEPS MUL_1802|M.ulcerans_Agy99 ---MRLVFAGTPETALPALHQLIDSPRHDVIAVLTRPDAASGRRGKPEPS Mflv_3730|M.gilvum_PYR-GCK ---MRLVFAGTPEPALPSLQRLIDSARHDVIAVLTRPDAAAGRRGRPSPS Mvan_2687|M.vanbaalenii_PYR-1 ---MRLVFAGTPEPALPSLQRLIDSDRHEVIAVMTRPDAVAGRRGRPSPS TH_1529|M.thermoresistible__bu ---MRLVFAGTPEAALPSLRRLIDXXRHEVVAVLTRPDAAAGRRARPAPS MSMEG_0014|M.smegmatis_MC2_155 MFPVRVVMFGYQTWGHRTLQALLKSR-HEVCLVVTHPTSDHAYES-IWAD MAB_2260|M.abscessus_ATCC_1997 ---MRVVFFGYQTWGYRTLQALIDLG-HEIVLAVTHPMSEDAYKA-IWAA :*:*: * . :* *:. *:: .:*:* : . .. . Mb1441|M.bovis_AF2122/97 PVAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLL Rv1406|M.tuberculosis_H37Rv PVAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLL MLBr_00552|M.leprae_Br4923 PVAREALDRGIPLLRPARPNSPVFVSELSEWAPECCVVVAYGALLGSPLL MAV_3372|M.avium_104 PVAREALDRGIPVLRPARPNSPEFVAELAQLAPDCCAVVAYGALLRDELL MMAR_2215|M.marinum_M PVARAALERDIPVLRPSRPNSAEFVAELSELAPQCCAVVAYGALLGDALL MUL_1802|M.ulcerans_Agy99 PVARAALERGIPVLRPSRPNSAEFVAELSELAPQCCAVVAYGALLGDALL Mflv_3730|M.gilvum_PYR-GCK PVAELAAAHGIPVLKPPRPNSEEFVAELAALAPDCCAVVAYGALLREELL Mvan_2687|M.vanbaalenii_PYR-1 PVAQLAAAHGIPVLKPARPNSGEFVAELSALSPDCCAVVAYGALLGDALL TH_1529|M.thermoresistible__bu PVAKLASEHGIPVLRPPSPNTDEFIAELTELAPDCCPVVAYGALLSERLL MSMEG_0014|M.smegmatis_MC2_155 SVEDLARGAGIEVLLAKRPT-PELVERVRELAPDVGVANNWRTRLPRELF MAB_2260|M.abscessus_ATCC_1997 PVEELAREHGIPAHFTKRVD-AETIDLVRSVDPDVIVVNSWYNRMPVELY .* * .* . : : *: . : : * Mb1441|M.bovis_AF2122/97 AVPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGP Rv1406|M.tuberculosis_H37Rv AVPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGP MLBr_00552|M.leprae_Br4923 AVPPRGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGP MAV_3372|M.avium_104 AVPPHGWINLHFSLLPAWRGAAPVQAAIAAGDTITGATTFRIEPALDSGP MMAR_2215|M.marinum_M GVPPQGWVNLHFSLLPAWRGAAPVQAAIAAGDAVTGATTFQIEPSLDSGP MUL_1802|M.ulcerans_Agy99 GVPPQGWVNLHFSLLPAWRGAAPVQAAIAAGDAVTGATTFQIEPSLDSGP Mflv_3730|M.gilvum_PYR-GCK AVPALGWVNLHFSVLPAWRGAAPVQAALAAGDEVTGATTFQIELSLDSGP Mvan_2687|M.vanbaalenii_PYR-1 AVPAHGWVNLHFSVLPAWRGAAPVQAALAAGDEVTGATTFQIERSLDSGP TH_1529|M.thermoresistible__bu AVPRHGWVNLHFSLLPAWRGAAPVQAAIAAGDTVTGASTFRIEPALDSGP MSMEG_0014|M.smegmatis_MC2_155 SIPKYGTVNLHDSLLPKFTGFSPVIWSLISGAGQTGLTAHFMDDELDTGD MAB_2260|M.abscessus_ATCC_1997 DLPPYGTLNFHDSLLPKFTGFSPVLWALISGESEFGLTVHRMDSGLDTGD :* * :*:* *:** : * :** :: :* * :.. :: **:* Mb1441|M.bovis_AF2122/97 IYGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPAD Rv1406|M.tuberculosis_H37Rv IYGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPAD MLBr_00552|M.leprae_Br4923 VYGVVTETIQPTDTAGDLLERLAVSGATLLSSTLDGIADAILTPRQQPVD MAV_3372|M.avium_104 IYGVVTEAIRPTDTAGELLARLAVSGAELLSATLDGIADSTLTPRPQPAE MMAR_2215|M.marinum_M VYGVVTETIRPTDTAGDLLGRLAVSGAELLSATLDGIAEGALTARPQPAD MUL_1802|M.ulcerans_Agy99 VYGVVTETIRPTDTAGDLLGRLAVSGAELLSATLDGIAEGALTARPQPAD Mflv_3730|M.gilvum_PYR-GCK VYGVVTETIRPTDTAGDLLGRLAESGAGLLEATMDGIEDGTLTAVPQPAE Mvan_2687|M.vanbaalenii_PYR-1 VYGVVTETIRPTDTAGDLLERLSVSGAGLLEATMDGIEDGTLTAVPQPPE TH_1529|M.thermoresistible__bu IYGVVTETIRPTDTAGDLLDRLADSGAELLERTLDGIEDGTLTAVPQPSE MSMEG_0014|M.smegmatis_MC2_155 ILLQRSVEITPTSTGTSLVYDTLDLIPDVLEDALDAIENGTATPVPQDLS MAB_2260|M.abscessus_ATCC_1997 ILVQRSLPIGPTDTGTELVLRGMELIPRVLAEALNALESGSAAWRPQNKA : : * **.*. .*: . :* :::.: . : * Mb1441|M.bovis_AF2122/97 GVSVAPKITVANARVRWDLPAAVVERRIRAVT-PNPGAWTLIGDLRVKLG Rv1406|M.tuberculosis_H37Rv GVSVAPKITVANARVRWDLPAAVVERRIRAVT-PNPGAWTLIGDLRVKLG MLBr_00552|M.leprae_Br4923 GVSFAPKITVEQARVCWDLPAPVVERRIRAVT-PNPGAWTLVGKLRVKLG MAV_3372|M.avium_104 GVSIAPKITVEQARVRWDLPAPVVERRIRAVT-PNPGAWTVIGDLRIKLG MMAR_2215|M.marinum_M GVTLAPKISVEQARVRWELPAPIIERRIRAVT-PNPGAWTLIGDLRVKLG MUL_1802|M.ulcerans_Agy99 GVTLAPKISVEQARVRWELPVPIIERRIRAVT-PNPGAWTLIGDLRVKLG Mflv_3730|M.gilvum_PYR-GCK GVSIAPKVSVDDARIRWELPAHVVDRRIRSVT-PNPGAWTMAGELRIKVG Mvan_2687|M.vanbaalenii_PYR-1 GVSVAPKVTVDDARIRWELPAHVVDRRVRSVT-PNPGAWTMIGDQRIKVG TH_1529|M.thermoresistible__bu GVSYAPKITVEAARIRWDLPAHVVERRIRAMT-PNPGAWTMIGDLRVKLG MSMEG_0014|M.smegmatis_MC2_155 QRTFFHKRSDRDSLVDWSWPAADIERFIRALSDPYPNAYTYFRGERLRLI MAB_2260|M.abscessus_ATCC_1997 ERTFCHKRSEQDSALDWAWPAEDLERFVRALSEPYPRAFAFYNTERIEVL : * : : : * *. ::* :*::: * * *:: *:.: Mb1441|M.bovis_AF2122/97 PVHLDA----AHRPSKPLPPGGIHVER-----TSVWIGTGSEP-----VR Rv1406|M.tuberculosis_H37Rv PVHLDA----AHRPSKPLPPGGIHVER-----TSVWIGTGSEP-----VR MLBr_00552|M.leprae_Br4923 PVRFDSGAVEVPRLLKPLLPGGIHVDH-----KSVWIGTGSDP-----VR MAV_3372|M.avium_104 PVRLGAAS-DLPAPPEPLPPGAIHVDR-----KSVWVGTASDP-----VR MMAR_2215|M.marinum_M PVYLDA----AVKPPGPLPPGAIQVDR-----KHVWVGTGSEP-----LR MUL_1802|M.ulcerans_Agy99 PVYLDA----AVEPPGPLPPGAIQVDR-----KHVWVGTGSEP-----LR Mflv_3730|M.gilvum_PYR-GCK PVTVPD------DGPKDLEPGEIRVGK-----KHVHVGTATDA-----VL Mvan_2687|M.vanbaalenii_PYR-1 PVTVAG------DGPKGLEPGEIRVDK-----KHIHVGTGSDA-----VL TH_1529|M.thermoresistible__bu PVTVDD-------DAEPLAPGEIRAGRDGSGKQAVWFGTGTHP-----VR MSMEG_0014|M.smegmatis_MC2_155 SAHVSR-------CTYGGTPGRVFIEE--NGGMVIVAGADAFRGRSPGLV MAB_2260|M.abscessus_ATCC_1997 EARVSE-------ARYGGTPGRVTVQE--QGG-AVVCGPGAHRAANRGLV . . ** : . : *. : : Mb1441|M.bovis_AF2122/97 LGQIQPPGKKLMNAADWARGARLDLAARAT---- Rv1406|M.tuberculosis_H37Rv LGQIQPPGKKLMNAADWARGARLDLAARAT---- MLBr_00552|M.leprae_Br4923 LSKVQPQGKKFMNAVDWAHGARLDPAARAS---- MAV_3372|M.avium_104 LDQIQPPGKKFMNAVDWARGARLDPAARAT---- MMAR_2215|M.marinum_M LGQVQPPGKKLMNAADWARGARLDPSVRAS---- MUL_1802|M.ulcerans_Agy99 LGQVQPPGKKLMNAADWARGARLDPSVRAS---- Mflv_3730|M.gilvum_PYR-GCK LGTVQPPGKKSMNAADWARGARAEDIRRAR---- Mvan_2687|M.vanbaalenii_PYR-1 LGTVQPPGKKPMNAADWARGARLDENGWAR---- TH_1529|M.thermoresistible__bu LGWIQPPGKKPMNAPDWARGARLDDTARAR---- MSMEG_0014|M.smegmatis_MC2_155 LDVVRTDDGIDHSALDYFGHGGGYLTATPEFATV MAB_2260|M.abscessus_ATCC_1997 ITRIRRADGSEVSGEEYFRRGG-YLDGGN----- : :: . .. :: .