For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
QEPVRVPPSAPARLVVLASGTGSLLNSLLDAAVADYPARIVAVGVDRDCRATEIAAQASVPAFTVRVSDH PSRDAWDAAITAAAAAHSPDLVVSAGFMRILGPQFLSKFHQRILNTHPALLPAFPGAHGVADALAYGVKV TGCTVHLVDAGMDTGPILAQQAIAVLDGDDEATLHERIKVVERKLLVDVVAGIATGGVTVIGRKAMIGRK ATIG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4543 | purN | - | 100% (215) | 5'-phosphoribosylglycinamide formyltransferase PurN |
M. marinum M | MMAR_1753 | purU | 2e-13 | 30.17% (179) | formyltetrahydrofolate deformylase PurU |
M. marinum M | MMAR_2215 | fmt | 7e-09 | 31.01% (129) | methionyl-tRNA formyltransferase Fmt |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0981 | purN | 1e-100 | 83.26% (215) | phosphoribosylglycinamide formyltransferase |
M. gilvum PYR-GCK | Mflv_1874 | purN | 3e-84 | 73.17% (205) | phosphoribosylglycinamide formyltransferase |
M. tuberculosis H37Rv | Rv0956 | purN | 1e-100 | 83.26% (215) | phosphoribosylglycinamide formyltransferase |
M. leprae Br4923 | MLBr_00160 | purN | 1e-93 | 78.50% (214) | phosphoribosylglycinamide formyltransferase |
M. abscessus ATCC 19977 | MAB_1063 | purN | 4e-80 | 70.39% (206) | phosphoribosylglycinamide formyltransferase |
M. avium 104 | MAV_1080 | purN | 4e-97 | 81.34% (209) | phosphoribosylglycinamide formyltransferase |
M. smegmatis MC2 155 | MSMEG_5516 | purN | 6e-80 | 70.94% (203) | phosphoribosylglycinamide formyltransferase |
M. thermoresistible (build 8) | TH_1361 | purN | 1e-88 | 78.33% (203) | PROBABLE 5'-PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE PURN |
M. ulcerans Agy99 | MUL_4713 | purN | 1e-117 | 98.14% (215) | phosphoribosylglycinamide formyltransferase |
M. vanbaalenii PYR-1 | Mvan_4857 | purN | 4e-85 | 74.63% (205) | phosphoribosylglycinamide formyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1874|M.gilvum_PYR-GCK MQSEAGGGEQQFHLRVPPSAPARVVVLASGAGSLLASLLSSAVGDFPARV Mvan_4857|M.vanbaalenii_PYR-1 MQPEAGGREERCVLRVPPSAPARLVVLASGTGSLLASLLKSAVGDYPARV MSMEG_5516|M.smegmatis_MC2_155 ---------------MPPSAPARLVVLASGAGSLLASLLEAATGEYPARV MMAR_4543|M.marinum_M ---------MQEPVRVPPSAPARLVVLASGTGSLLNSLLDAAVADYPARI MUL_4713|M.ulcerans_Agy99 ---------MQEPVRVPPSAPARLVVLASGTGSLLNSLLDAAVADYPARI Mb0981|M.bovis_AF2122/97 ---------MQEPLRVPPSAPARLVVLASGTGSLLRSLLDAAVGDYPARV Rv0956|M.tuberculosis_H37Rv ---------MQEPLRVPPSAPARLVVLASGTGSLLRSLLDAAVGDYPARV MLBr_00160|M.leprae_Br4923 ---------MQEPLCVSPSAPSRVVVLASGTGSLLGSLIDASVGNYPARV MAV_1080|M.avium_104 ---------MVEPLHVPPNAPARVVVLASGTGSLLSSLIDAAVGDYPARV TH_1361|M.thermoresistible__bu ---------------VPPSAPARVVVLASGTGSLLAALLEAAVGDYPARV MAB_1063|M.abscessus_ATCC_1997 ------MSVPSQSVEIAPSAPARVVVLASGTGTLLRSLLDAATGDFPARI :.*.**:*:******:*:** :*:.::..::***: Mflv_1874|M.gilvum_PYR-GCK VAVGTDRPCAALDIAAKADVPTFTVALTDHPDRTAWDAAITEATAAHAPD Mvan_4857|M.vanbaalenii_PYR-1 VAVGTDRVCAALDIASGAAIPTFTVPLSEYPDRAAWDAALADATAAHRPD MSMEG_5516|M.smegmatis_MC2_155 VAVGTDRKCAALDVAAAADVPTYTVRLADHADRAAWDAALTAATAEHHPD MMAR_4543|M.marinum_M VAVGVDRDCRATEIAAQASVPAFTVRVSDHPSRDAWDAAITAAAAAHSPD MUL_4713|M.ulcerans_Agy99 VAVGVDRDCRATEVAAQASVPAFTVRVSDHPSRDAWNAAITAATAAHSPD Mb0981|M.bovis_AF2122/97 VAVGVDRECRAAEIAAEASVPVFTVRLADHPSRDAWDVAITAATAAHEPD Rv0956|M.tuberculosis_H37Rv VAVGVDRECRAAEIAAEASVPVFTVRLADHPSRDAWDVAITAATAAHEPD MLBr_00160|M.leprae_Br4923 VAVGVDRDCGATKIAKAASVPTFTVRLADPPGRDAWDAKITEAVASYKPD MAV_1080|M.avium_104 VAVGADRDCLATQIAAAASLPSFTVRLGDHPDRAAWDAAITEATAAHSPD TH_1361|M.thermoresistible__bu VAVGTDRDCAALEIAAAANVPTFTVRLRDYPDRQAWDAAITEAVAAHQPD MAB_1063|M.abscessus_ATCC_1997 VAVGTDRPCPALDIAADAQLPSYMVRLGDYDSREQWDAAIAEATAVHRPD ****.** * * .:* * :* : * : : .* *:. :: *.* : ** Mflv_1874|M.gilvum_PYR-GCK IVVAAGFMKILGAGFLSRFPGRVLNSHPALLPAFPGAHAVRDALAYGVRV Mvan_4857|M.vanbaalenii_PYR-1 LVVSAGFMKILGPQFLSTFPGRVLNTHPALLPAFPGAHAVRDALAYGVRV MSMEG_5516|M.smegmatis_MC2_155 LVVSAGFMKILGAEFLSRFPGRVVNTHPALLPAFPGAHAVREALNYGVRV MMAR_4543|M.marinum_M LVVSAGFMRILGPQFLSKFHQRILNTHPALLPAFPGAHGVADALAYGVKV MUL_4713|M.ulcerans_Agy99 LVVSAGFMRILGPQFLSKFHQRILNTHPALLPAFPGAHGVADALAYGVKV Mb0981|M.bovis_AF2122/97 LVVSAGFMRILGPQFLSRFYGRTLNTHPALLPAFPGTHGVADALAYGVKV Rv0956|M.tuberculosis_H37Rv LVVSAGFMRILGPQFLSRFYGRTLNTHPALLPAFPGTHGVADALAYGVKV MLBr_00160|M.leprae_Br4923 LVVLAGFMRILGPQFLARFFGRIVNTHPALLPAFPGTHGVADALAYGVKV MAV_1080|M.avium_104 LVVSAGFMKILGPQFLSRFYGRVINTHPALLPAFPGAHGVAEALAYGVKV TH_1361|M.thermoresistible__bu LVVSAGFMKILGPHFLSRFQGRVLNTHPALLPAFPGAHAVADALSYGVQV MAB_1063|M.abscessus_ATCC_1997 LVVSAGFMKILGPQFLSQFLGRVINTHPALLPSFPGAHAVPEALAHGVKI :** ****:***. **: * * :*:******:***:*.* :** :**:: Mflv_1874|M.gilvum_PYR-GCK TGCTVHLVDAGTDTGPIVAQQAVAVYDDDDESALHERIKVIERRLLVDVV Mvan_4857|M.vanbaalenii_PYR-1 TGCTVHLVDAGTDTGPIVAQQAVTVLDGDDESSLHERIKVIERQLLVDVV MSMEG_5516|M.smegmatis_MC2_155 TGCTVHLVDSGVDTGPILAQQVVEIDDDDTEETLHERIKVVERRLLVDVL MMAR_4543|M.marinum_M TGCTVHLVDAGMDTGPILAQQAIAVLDGDDEATLHERIKVVERKLLVDVV MUL_4713|M.ulcerans_Agy99 TGCTVHLVDAGMDTGPILAQQAIAVLDGDDEATLHERIKVVERKLLVDVV Mb0981|M.bovis_AF2122/97 TGATVHLVDAGTDTGPILAQQPVPVLDGDDEETLHERIKVTERRLLVAAV Rv0956|M.tuberculosis_H37Rv TGATVHLVDAGTDTGPILAQQPVPVLDGDDEETLHERIKVTERRLLVAAV MLBr_00160|M.leprae_Br4923 TGATVHLVDAGTDTGPILAQQSVPVLDGDDTAALHERIKVIERRLLVDVV MAV_1080|M.avium_104 TGCTVHLVDAGTDTGPILAQQSVPVLDGDDEQTLHERIKVTERKLLVDVV TH_1361|M.thermoresistible__bu TGCTVHLVDAGTDTGPIIAQRAVPVLKGDDEATLHERIKVVERQLLVEVL MAB_1063|M.abscessus_ATCC_1997 TGCTVHLVDAGMDTGPILAQQAVPVDRDDDEASLHERIKVVERTLLVDVL **.******:* *****:**: : : .* :******* ** *** .: Mflv_1874|M.gilvum_PYR-GCK AAVASRGVTWTGRKATLG------ Mvan_4857|M.vanbaalenii_PYR-1 AAMATRGMTWTGRKVNLG------ MSMEG_5516|M.smegmatis_MC2_155 AALATRGVIWTGRKATFG------ MMAR_4543|M.marinum_M AGIATGGVTVIGRKAMIGRKATIG MUL_4713|M.ulcerans_Agy99 AGIAAGGVTVIGRKAMIGRKATIG Mb0981|M.bovis_AF2122/97 AALATHGVTVVGRTATMGRKVTIG Rv0956|M.tuberculosis_H37Rv AALATHGVTVVGRTATMGRKVTIG MLBr_00160|M.leprae_Br4923 AVIATGGVTLVGRKATIGRKATIE MAV_1080|M.avium_104 AAIATGGLTLVGRKATIG------ TH_1361|M.thermoresistible__bu AALATRGVTWSGRKATIG------ MAB_1063|M.abscessus_ATCC_1997 AAVATKGLTWNGRRASIK------ * :*: *: ** . :