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M. tuberculosis H37Rv Rv0956 (purN)

annotation: phosphoribosylglycinamide formyltransferase
coordinates: 1067561 - 1068208
length: 215

VQEPLRVPPSAPARLVVLASGTGSLLRSLLDAAVGDYPARVVAVGVDRECRAAEIAAEASVPVFTVRLAD
HPSRDAWDVAITAATAAHEPDLVVSAGFMRILGPQFLSRFYGRTLNTHPALLPAFPGTHGVADALAYGVK
VTGATVHLVDAGTDTGPILAQQPVPVLDGDDEETLHERIKVTERRLLVAAVAALATHGVTVVGRTATMGR
KVTIG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0956purN-100% (215)phosphoribosylglycinamide formyltransferase
M. tuberculosis H37RvRv2964purU5e-1140.38% (104) formyltetrahydrofolate deformylase
M. tuberculosis H37RvRv1406fmt1e-0627.70% (148) methionyl-tRNA formyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0981purN1e-119100.00% (215) phosphoribosylglycinamide formyltransferase
M. gilvum PYR-GCKMflv_1874purN1e-8375.12% (205) phosphoribosylglycinamide formyltransferase
M. leprae Br4923MLBr_00160purN5e-9479.91% (214) phosphoribosylglycinamide formyltransferase
M. abscessus ATCC 19977MAB_1063purN7e-7868.45% (206) phosphoribosylglycinamide formyltransferase
M. marinum MMMAR_4543purN1e-10083.26% (215) 5'-phosphoribosylglycinamide formyltransferase PurN
M. avium 104MAV_1080purN2e-9682.30% (209) phosphoribosylglycinamide formyltransferase
M. smegmatis MC2 155MSMEG_5516purN2e-8173.89% (203) phosphoribosylglycinamide formyltransferase
M. thermoresistible (build 8)TH_1361purN2e-8878.82% (203) PROBABLE 5'-PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE PURN
M. ulcerans Agy99MUL_4713purN2e-9982.33% (215) phosphoribosylglycinamide formyltransferase
M. vanbaalenii PYR-1Mvan_4857purN3e-8475.12% (205) phosphoribosylglycinamide formyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1874|M.gilvum_PYR-GCK          MQSEAGGGEQQFHLRVPPSAPARVVVLASGAGSLLASLLSSAVGDFPARV
Mvan_4857|M.vanbaalenii_PYR-1       MQPEAGGREERCVLRVPPSAPARLVVLASGTGSLLASLLKSAVGDYPARV
MSMEG_5516|M.smegmatis_MC2_155      ---------------MPPSAPARLVVLASGAGSLLASLLEAATGEYPARV
Rv0956|M.tuberculosis_H37Rv         ---------MQEPLRVPPSAPARLVVLASGTGSLLRSLLDAAVGDYPARV
Mb0981|M.bovis_AF2122/97            ---------MQEPLRVPPSAPARLVVLASGTGSLLRSLLDAAVGDYPARV
MMAR_4543|M.marinum_M               ---------MQEPVRVPPSAPARLVVLASGTGSLLNSLLDAAVADYPARI
MUL_4713|M.ulcerans_Agy99           ---------MQEPVRVPPSAPARLVVLASGTGSLLNSLLDAAVADYPARI
MLBr_00160|M.leprae_Br4923          ---------MQEPLCVSPSAPSRVVVLASGTGSLLGSLIDASVGNYPARV
MAV_1080|M.avium_104                ---------MVEPLHVPPNAPARVVVLASGTGSLLSSLIDAAVGDYPARV
TH_1361|M.thermoresistible__bu      ---------------VPPSAPARVVVLASGTGSLLAALLEAAVGDYPARV
MAB_1063|M.abscessus_ATCC_1997      ------MSVPSQSVEIAPSAPARVVVLASGTGTLLRSLLDAATGDFPARI
                                                   :.*.**:*:******:*:** :*:.::..::***:

Mflv_1874|M.gilvum_PYR-GCK          VAVGTDRPCAALDIAAKADVPTFTVALTDHPDRTAWDAAITEATAAHAPD
Mvan_4857|M.vanbaalenii_PYR-1       VAVGTDRVCAALDIASGAAIPTFTVPLSEYPDRAAWDAALADATAAHRPD
MSMEG_5516|M.smegmatis_MC2_155      VAVGTDRKCAALDVAAAADVPTYTVRLADHADRAAWDAALTAATAEHHPD
Rv0956|M.tuberculosis_H37Rv         VAVGVDRECRAAEIAAEASVPVFTVRLADHPSRDAWDVAITAATAAHEPD
Mb0981|M.bovis_AF2122/97            VAVGVDRECRAAEIAAEASVPVFTVRLADHPSRDAWDVAITAATAAHEPD
MMAR_4543|M.marinum_M               VAVGVDRDCRATEIAAQASVPAFTVRVSDHPSRDAWDAAITAAAAAHSPD
MUL_4713|M.ulcerans_Agy99           VAVGVDRDCRATEVAAQASVPAFTVRVSDHPSRDAWNAAITAATAAHSPD
MLBr_00160|M.leprae_Br4923          VAVGVDRDCGATKIAKAASVPTFTVRLADPPGRDAWDAKITEAVASYKPD
MAV_1080|M.avium_104                VAVGADRDCLATQIAAAASLPSFTVRLGDHPDRAAWDAAITEATAAHSPD
TH_1361|M.thermoresistible__bu      VAVGTDRDCAALEIAAAANVPTFTVRLRDYPDRQAWDAAITEAVAAHQPD
MAB_1063|M.abscessus_ATCC_1997      VAVGTDRPCPALDIAADAQLPSYMVRLGDYDSREQWDAAIAEATAVHRPD
                                    ****.** * * .:*  * :* : * : :  .*  *:. :: *.* : **

Mflv_1874|M.gilvum_PYR-GCK          IVVAAGFMKILGAGFLSRFPGRVLNSHPALLPAFPGAHAVRDALAYGVRV
Mvan_4857|M.vanbaalenii_PYR-1       LVVSAGFMKILGPQFLSTFPGRVLNTHPALLPAFPGAHAVRDALAYGVRV
MSMEG_5516|M.smegmatis_MC2_155      LVVSAGFMKILGAEFLSRFPGRVVNTHPALLPAFPGAHAVREALNYGVRV
Rv0956|M.tuberculosis_H37Rv         LVVSAGFMRILGPQFLSRFYGRTLNTHPALLPAFPGTHGVADALAYGVKV
Mb0981|M.bovis_AF2122/97            LVVSAGFMRILGPQFLSRFYGRTLNTHPALLPAFPGTHGVADALAYGVKV
MMAR_4543|M.marinum_M               LVVSAGFMRILGPQFLSKFHQRILNTHPALLPAFPGAHGVADALAYGVKV
MUL_4713|M.ulcerans_Agy99           LVVSAGFMRILGPQFLSKFHQRILNTHPALLPAFPGAHGVADALAYGVKV
MLBr_00160|M.leprae_Br4923          LVVLAGFMRILGPQFLARFFGRIVNTHPALLPAFPGTHGVADALAYGVKV
MAV_1080|M.avium_104                LVVSAGFMKILGPQFLSRFYGRVINTHPALLPAFPGAHGVAEALAYGVKV
TH_1361|M.thermoresistible__bu      LVVSAGFMKILGPHFLSRFQGRVLNTHPALLPAFPGAHAVADALSYGVQV
MAB_1063|M.abscessus_ATCC_1997      LVVSAGFMKILGPQFLSQFLGRVINTHPALLPSFPGAHAVPEALAHGVKI
                                    :** ****:***. **: *  * :*:******:***:*.* :** :**::

Mflv_1874|M.gilvum_PYR-GCK          TGCTVHLVDAGTDTGPIVAQQAVAVYDDDDESALHERIKVIERRLLVDVV
Mvan_4857|M.vanbaalenii_PYR-1       TGCTVHLVDAGTDTGPIVAQQAVTVLDGDDESSLHERIKVIERQLLVDVV
MSMEG_5516|M.smegmatis_MC2_155      TGCTVHLVDSGVDTGPILAQQVVEIDDDDTEETLHERIKVVERRLLVDVL
Rv0956|M.tuberculosis_H37Rv         TGATVHLVDAGTDTGPILAQQPVPVLDGDDEETLHERIKVTERRLLVAAV
Mb0981|M.bovis_AF2122/97            TGATVHLVDAGTDTGPILAQQPVPVLDGDDEETLHERIKVTERRLLVAAV
MMAR_4543|M.marinum_M               TGCTVHLVDAGMDTGPILAQQAIAVLDGDDEATLHERIKVVERKLLVDVV
MUL_4713|M.ulcerans_Agy99           TGCTVHLVDAGMDTGPILAQQAIAVLDGDDEATLHERIKVVERKLLVDVV
MLBr_00160|M.leprae_Br4923          TGATVHLVDAGTDTGPILAQQSVPVLDGDDTAALHERIKVIERRLLVDVV
MAV_1080|M.avium_104                TGCTVHLVDAGTDTGPILAQQSVPVLDGDDEQTLHERIKVTERKLLVDVV
TH_1361|M.thermoresistible__bu      TGCTVHLVDAGTDTGPIIAQRAVPVLKGDDEATLHERIKVVERQLLVEVL
MAB_1063|M.abscessus_ATCC_1997      TGCTVHLVDAGMDTGPILAQQAVPVDRDDDEASLHERIKVVERTLLVDVL
                                    **.******:* *****:**: : :  .*   :******* ** *** .:

Mflv_1874|M.gilvum_PYR-GCK          AAVASRGVTWTGRKATLG------
Mvan_4857|M.vanbaalenii_PYR-1       AAMATRGMTWTGRKVNLG------
MSMEG_5516|M.smegmatis_MC2_155      AALATRGVIWTGRKATFG------
Rv0956|M.tuberculosis_H37Rv         AALATHGVTVVGRTATMGRKVTIG
Mb0981|M.bovis_AF2122/97            AALATHGVTVVGRTATMGRKVTIG
MMAR_4543|M.marinum_M               AGIATGGVTVIGRKAMIGRKATIG
MUL_4713|M.ulcerans_Agy99           AGIAAGGVTVIGRKAMIGRKATIG
MLBr_00160|M.leprae_Br4923          AVIATGGVTLVGRKATIGRKATIE
MAV_1080|M.avium_104                AAIATGGLTLVGRKATIG------
TH_1361|M.thermoresistible__bu      AALATRGVTWSGRKATIG------
MAB_1063|M.abscessus_ATCC_1997      AAVATKGLTWNGRRASIK------
                                    * :*: *:   ** . :