For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MKGDMLGLPDRIHACLFDLDGVLTDTASVHRRAWKAMFDEYLSDIADGAEDPDARYTPFDAGADYETYVD GKPRADGIRSFLGSRLIDVDEATVTRLGDRKNEMFRKTLKSDGIEVFDGSRRYLQAAADAGLRRAVVSSS ANTREVLELTGLDRYVEVRVDGVTLREENLPGKPAPDTYLRAAELLGVDPAEAAVFEDALSGVAAGRAGD FGLVVGVDRTGQAQALRDKGADIVITDLGELLT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1072 | - | - | 100% (243) | beta-phosphoglucomutase family hydrolase |
| M. gilvum PYR-GCK | Mflv_3054 | - | 2e-10 | 29.88% (241) | HAD family hydrolase |
| M. gilvum PYR-GCK | Mflv_4989 | - | 3e-08 | 46.43% (56) | HAD family hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3433 | - | 6e-85 | 63.39% (254) | hydrolase |
| M. tuberculosis H37Rv | Rv3400 | - | 6e-85 | 63.39% (254) | hydrolase |
| M. leprae Br4923 | MLBr_00393 | - | 6e-79 | 59.45% (254) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_2130 | - | 6e-09 | 25.24% (206) | putative hydrolase |
| M. marinum M | MMAR_1144 | - | 1e-84 | 64.37% (247) | hydrolase |
| M. avium 104 | MAV_4350 | - | 4e-87 | 65.99% (247) | beta-phosphoglucomutase hydrolase |
| M. smegmatis MC2 155 | MSMEG_1707 | - | 3e-11 | 32.76% (232) | phosphatase YfbT |
| M. thermoresistible (build 8) | TH_2142 | - | 6e-88 | 68.15% (248) | PROBABLE HYDROLASE |
| M. ulcerans Agy99 | MUL_0908 | - | 5e-45 | 60.67% (150) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_5751 | - | 1e-102 | 79.50% (239) | beta-phosphoglucomutase family hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1072|M.gilvum_PYR-GCK ------------MKGDMLGLPDRIHACLFDLDGVLTDTASVHRRAWKAMF
Mvan_5751|M.vanbaalenii_PYR-1 ----------------MLGLPDRIRACLFDLDGVLTDTASVHRRAWKAMF
TH_2142|M.thermoresistible__bu ----------------VLGLPDHIRACLFDLDGVLTDTAGVHRKAWKAMF
MMAR_1144|M.marinum_M ----------------MLGLPEKVRACLFDLDGVLTDTASVHTKAWKAMF
MUL_0908|M.ulcerans_Agy99 ----------------MLGLPEKVRACLFDLDGVLTDTASVHTKAWKAMF
MAV_4350|M.avium_104 MVEWIPPDPNHRKRVPVLGLPEKVHACLFDLDGVLTDTASVHTKAWKAMF
Mb3433|M.bovis_AF2122/97 MANWYRPNYP-EVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMF
Rv3400|M.tuberculosis_H37Rv MANWYRPNYP-EVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMF
MLBr_00393|M.leprae_Br4923 MANWDHPTSK--VRSTVLGLPEQVRACLFDLDGVLTDTASVHAKAWQTMF
MSMEG_1707|M.smegmatis_MC2_155 ---------------MTSHKTFPIAGILFDSDGVLVDSHEAAATAWNHWA
MAB_2130|M.abscessus_ATCC_1997 -----------------------MRAVLWDMDGTLIESEKLWDISMGELC
: . *:* **.* :: :
Mflv_1072|M.gilvum_PYR-GCK DEYLSDIADGAEDPDARYTPFDAGADYETYVDGKPRADGIRSFLGSRLID
Mvan_5751|M.vanbaalenii_PYR-1 DEYLRSRAEDG----VPYVPFDAGADYERYVDGKPRLDGIRSFLGSRGIV
TH_2142|M.thermoresistible__bu DEYLRDRAARTG---AEFVPFDIDADYHHYVDGKKREDGVRSFLASRSIK
MMAR_1144|M.marinum_M DAYLSERAERTG---GQFVPFDPAADYRQYVDGKKREDGVRSFLSSRGIQ
MUL_0908|M.ulcerans_Agy99 DAYLSERAERTG---GQFVPFDPAADYRQYVDGKKREDGVRSFLSSRGIQ
MAV_4350|M.avium_104 DAYLADRAKRTG---ETFVPFDPAADYRKYVDGKKREDGVRSFLQSRGIH
Mb3433|M.bovis_AF2122/97 DAYLAERAERTG---EKFVPFDPAADYHTYVDGKKREDGVRSFLSSRAIE
Rv3400|M.tuberculosis_H37Rv DAYLAERAERTG---EKFVPFDPAADYHTYVDGKKREDGVRSFLSSRAIE
MLBr_00393|M.leprae_Br4923 DTYLYQRAKHTG---ENFVPFDPTADYRQYVDGKKREDGVRSFLGSRGIT
MSMEG_1707|M.smegmatis_MC2_155 RTWAPG--------------FDFHRDAQH---GRRLSDVVAELVG-----
MAB_2130|M.abscessus_ATCC_1997 RKLGG----------------EMTPELRTALVGGAADATMRMIFTALELE
: : . * : :.
Mflv_1072|M.gilvum_PYR-GCK VDE---------ATVTRLGDRKNEMFRKTLKSDGIEVFDGSRRYLQAAAD
Mvan_5751|M.vanbaalenii_PYR-1 APD---------ETVTLLGDRKNHVFTQTLHTDGVTVFEGSRRYLQAAAA
TH_2142|M.thermoresistible__bu LPDGHYDDDPATETVHGLGNRKNVVFHQILEAEGVEVFEGSRRYLAAVVD
MMAR_1144|M.marinum_M LPDGSPDDPGDLETVYGLGNRKNDMFQKVLKKDGVDVFEGSRRYLEAVSA
MUL_0908|M.ulcerans_Agy99 LPDGSPDDPGDLETVYGLGNRKNDMFQKVLKKDGVDVFEGSRRYLEAVSA
MAV_4350|M.avium_104 LPDGSPDDAGDAETIYGLGNRKNDMFQKVLKQDGVKVFDGSRRYLEAASA
Mb3433|M.bovis_AF2122/97 IPDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSRRYLEAVTA
Rv3400|M.tuberculosis_H37Rv IPDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSRRYLEAVTA
MLBr_00393|M.leprae_Br4923 LPEGSADNSGDVETIYGLGNRKDDLFRQVLKEHGIEVFDGSRRYLEAITY
MSMEG_1707|M.smegmatis_MC2_155 ------------DGDSALATKVLTELEIEMAT-EVPAMAGAVDLLSSSPA
MAB_2130|M.abscessus_ATCC_1997 PDP----------VRMASENDWLHQYTGELFATGLIWCDGAQEMLGQLAA
: *: *
Mflv_1072|M.gilvum_PYR-GCK AGLRRAVVSSSANTREVLELTGLDRYVEVRVDGVTLREENLPGKPAPDTY
Mvan_5751|M.vanbaalenii_PYR-1 AGLRRAVVSSSANTRTILELTGLDVYVEARVDGVTLREEHLPGKPAPDAF
TH_2142|M.thermoresistible__bu AGLGVAVVTSSANGRQILEVTGLDRFVQYRVDGVTMREEQLPGKPAPDSF
MMAR_1144|M.marinum_M AGLSIAVVSSSANTRDVLEITGLGRFIQQRVDGVRLREEHIAGKPAPDSY
MUL_0908|M.ulcerans_Agy99 AGLSIAVVSSSANTRDPSTCT-----------------------------
MAV_4350|M.avium_104 AGLGIAVVSSSANTRDVLEVTGLDRFVQQRVDGITLREEHLAGKPAPDSF
Mb3433|M.bovis_AF2122/97 AGLGVAVVSSSANTRDVLATTGLDRFVQQRVDGVTLREEHIAGKPAPDSF
Rv3400|M.tuberculosis_H37Rv AGLGVAVVSSSANTRDVLATTGLDRFVQQRVDGVTLREEHIAGKPAPDSF
MLBr_00393|M.leprae_Br4923 AGLGVAVVSSSTNTRDVLKITGLDRFVQQQVDGITLREEHIAGKPAPDSY
MSMEG_1707|M.smegmatis_MC2_155 DRWAVVTSGAREMAAARLLSAGLP-----TPRVLVSADDVTAGKPAPEPY
MAB_2130|M.abscessus_ATCC_1997 EQMPMALVTNTIRS---LTDQALKTIGTHWFTESVCGDEVPAGKPAPDPY
.
Mflv_1072|M.gilvum_PYR-GCK LRAAELLGVDPAEAAVFEDALSGVAAGRAGDFGLVVGVDRTG--------
Mvan_5751|M.vanbaalenii_PYR-1 LRAAELLGVAPADAAVFEDALSGVAAGRAGGFGLVVGVDRTG--------
TH_2142|M.thermoresistible__bu LRAAELLQVPPQHGAVFEDALSGVAAGRAGGFGLVVGVDRVG--------
MMAR_1144|M.marinum_M LRGAQLLDTAPDAAAVFEDAISGVQAGRAGNFGYVVGVDRVG--------
MUL_0908|M.ulcerans_Agy99 -----MANCSP---------MS----------AFSICVPRRV--------
MAV_4350|M.avium_104 LRGAQLLDVPAGAAAVFEDALSGVAAGRAGNFGFVVGVDRVG--------
Mb3433|M.bovis_AF2122/97 LRAAELLGVTPDAAAVFEDALSGVAAGRAGNFAVVVGINRTGR-------
Rv3400|M.tuberculosis_H37Rv LRAAELLGVTPDAAAVFEDALSGVAAGRAGNFAVVVGINRTGR-------
MLBr_00393|M.leprae_Br4923 LRGAQLLDVAPDAAAVFEDALSGVQAGLSGHFGFVVGINRTGR-------
MSMEG_1707|M.smegmatis_MC2_155 LTGAHLLGLEPRVCAVFEDAHLGILAARAANVGFVVGVGAQTIGE-----
MAB_2130|M.abscessus_ATCC_1997 LRAAALLGVEPRDCLAIEDSVTGAAAAEAAGCAVLVVPNHVEVPAGARRR
: . . :
Mflv_1072|M.gilvum_PYR-GCK --------QAQALRDKGADIVITDLGELLT-
Mvan_5751|M.vanbaalenii_PYR-1 --------QSEALRRNGADIVVTDLGELLSP
TH_2142|M.thermoresistible__bu --------QAEALRRNGADIVVTDLAELLTP
MMAR_1144|M.marinum_M --------QAEDLRRNGADVVITDLAELLQS
MUL_0908|M.ulcerans_Agy99 --------PALLISR----LVSWGIVD----
MAV_4350|M.avium_104 --------QAEDLRRNGADVVVSDLAELLAS
Mb3433|M.bovis_AF2122/97 ------AAQAAQLRRHGADVVVTDLAELL--
Rv3400|M.tuberculosis_H37Rv ------AAQAAQLRRHGADVVVTDLAELL--
MLBr_00393|M.leprae_Br4923 ------VDQAEELRRIGANVVVTDLAELL--
MSMEG_1707|M.smegmatis_MC2_155 -DVDVSVADLSGITFDGSHLVIEADAVLTR-
MAB_2130|M.abscessus_ATCC_1997 HAASLSGLSVRDLRDAHADVLAATTCKPI--
: ::