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MRAVLWDMDGTLIESEKLWDISMGELCRKLGGEMTPELRTALVGGAADATMRMIFTALELEPDPVRMASE NDWLHQYTGELFATGLIWCDGAQEMLGQLAAEQMPMALVTNTIRSLTDQALKTIGTHWFTESVCGDEVPA GKPAPDPYLRAAALLGVEPRDCLAIEDSVTGAAAAEAAGCAVLVVPNHVEVPAGARRRHAASLSGLSVRD LRDAHADVLAATTCKPI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2130 | - | - | 100% (227) | putative hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3433 | - | 2e-13 | 28.39% (236) | hydrolase |
| M. gilvum PYR-GCK | Mflv_3054 | - | 4e-74 | 61.86% (215) | HAD family hydrolase |
| M. tuberculosis H37Rv | Rv3400 | - | 2e-13 | 28.39% (236) | hydrolase |
| M. leprae Br4923 | MLBr_00393 | - | 3e-06 | 33.33% (90) | putative hydrolase |
| M. marinum M | MMAR_0580 | - | 1e-08 | 27.32% (183) | hydrolase |
| M. avium 104 | MAV_1053 | - | 2e-08 | 28.65% (171) | hypothetical protein MAV_1053 |
| M. smegmatis MC2 155 | MSMEG_4183 | - | 1e-75 | 62.39% (218) | phosphoglycolate phosphatase, chromosomal |
| M. thermoresistible (build 8) | TH_0959 | - | 2e-73 | 62.62% (214) | phosphoglycolate phosphatase, chromosomal |
| M. ulcerans Agy99 | MUL_0545 | - | 3e-08 | 26.78% (183) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_3473 | - | 3e-76 | 62.84% (218) | HAD family hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0580|M.marinum_M -----------------MPELHAAALLFDMDGTLVDST--------AVVE
MUL_0545|M.ulcerans_Agy99 -----------------MPELHAAALLFDVDGTLVDST--------AVVE
Mb3433|M.bovis_AF2122/97 MANWYRPNYPEVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMFD
Rv3400|M.tuberculosis_H37Rv MANWYRPNYPEVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMFD
MLBr_00393|M.leprae_Br4923 MANWDHP-TSKVRSTVLGLPEQVRACLFDLDGVLTDTASVHAKAWQTMFD
MSMEG_4183|M.smegmatis_MC2_155 ----------------------MLAVLWDMDGTLVDSE--------KLWD
TH_0959|M.thermoresistible__bu -----------------------------MDGTLVDSE--------RLWD
MAB_2130|M.abscessus_ATCC_1997 ----------------------MRAVLWDMDGTLIESE--------KLWD
Mflv_3054|M.gilvum_PYR-GCK -------------------------MLWDMDGTLVDSE--------KLWD
Mvan_3473|M.vanbaalenii_PYR-1 ------MLRGSRRDTAACQNGRVRAVLWDMDGTLVDSE--------KLWD
MAV_1053|M.avium_104 ------MKPEGLTMVREFDPAPITTLLCDADDNLFPSERPAFAASVEVIN
*. * : : :
MMAR_0580|M.marinum_M ATWGAF---AELHSLDLAE------VLAFAHGRPTAATVRHFLS------
MUL_0545|M.ulcerans_Agy99 ATWGAF---AELHSLDLAE------VLAFAHGRPTAATVRHFLS------
Mb3433|M.bovis_AF2122/97 AYLAER---AERTGEKFVPFDPAADYHTYVDGKKREDGVRSFLSSRAIEI
Rv3400|M.tuberculosis_H37Rv AYLAER---AERTGEKFVPFDPAADYHTYVDGKKREDGVRSFLSSRAIEI
MLBr_00393|M.leprae_Br4923 TYLYQR---AKHTGENFVPFDPTADYRQYVDGKKREDGVRSFLGSRGITL
MSMEG_4183|M.smegmatis_MC2_155 ISMHAL---YARMGAVLTP-----EVRESTVGGSSETVMRIVYEDIGLEP
TH_0959|M.thermoresistible__bu LSLREL---YRRLGRELRP-----EVRAATVGGAADTVMRIVYDDLGLDP
MAB_2130|M.abscessus_ATCC_1997 ISMGEL---CRKLGGEMTP-----ELRTALVGGAADATMRMIFTALELEP
Mflv_3054|M.gilvum_PYR-GCK VSLSKL---YETYDAEMSR-----ETRTALVGASAEETMVTVYTELGLDL
Mvan_3473|M.vanbaalenii_PYR-1 VSLSAL---YETFGGVMSR-----ETRATLVGASAEETMVTVYTELGLDL
MAV_1053|M.avium_104 RFLARFGVAAPFTAEQLRKQAVGKNFRSTALDLAVASGVPIDQTLAQGRP
: . :
MMAR_0580|M.marinum_M -----HPALVASETRRLVEHEESTT------EGVREVPGAA---EFIAAL
MUL_0545|M.ulcerans_Agy99 -----HPALVASETRRLVEHEESTT------EGVREVPGAA---EFIAAL
Mb3433|M.bovis_AF2122/97 PDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSR---RYLEAV
Rv3400|M.tuberculosis_H37Rv PDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSR---RYLEAV
MLBr_00393|M.leprae_Br4923 PEGSADNSGDVETIYGLGNRKDDLFRQVLKEHGIEVFDGSR---RYLEAI
MSMEG_4183|M.smegmatis_MC2_155 -----DPAAMAESADWLHAYTGELF-----EQGLPWRPGAQ---EMLDAL
TH_0959|M.thermoresistible__bu -----DPEAMARTADWLHDYTGELF-----ASGLPWCAGAR---ELLDEL
MAB_2130|M.abscessus_ATCC_1997 -----DPVRMASENDWLHQYTGELF-----ATGLIWCDGAQ---EMLGQL
Mflv_3054|M.gilvum_PYR-GCK -----DPAAMAESIRWLHAHTAELF-----DEGLPWCDGAF---ELLERL
Mvan_3473|M.vanbaalenii_PYR-1 -----DPEAMAESVRWLHDHTAELF-----DGGLPWCDGAR---EMLEGL
MAV_1053|M.avium_104 EAVVASADDTAADRALCADELEQWVLQEREQVTAHLAATLRPDPEVLAPL
. . . : :
MMAR_0580|M.marinum_M PRSAWAVVT-----SASRVLA----SNRMRAAGIPLPDVLISA-DDITRG
MUL_0545|M.ulcerans_Agy99 PRSAWAVVT-----SASRVLA----SNRMRAAGIPLPDVLISA-DDITRG
Mb3433|M.bovis_AF2122/97 TAAGLGVAVVSSSANTRDVLA----TTGLDRFVQQRVDGVTLR-EEHIAG
Rv3400|M.tuberculosis_H37Rv TAAGLGVAVVSSSANTRDVLA----TTGLDRFVQQRVDGVTLR-EEHIAG
MLBr_00393|M.leprae_Br4923 TYAGLGVAVVSSSTNTRDVLK----ITGLDRFVQQQVDGITLR-EEHIAG
MSMEG_4183|M.smegmatis_MC2_155 VAAEVPMALVT---NTRRDLA----ERALNSIGRHYFSVSVCG-DEVPSG
TH_0959|M.thermoresistible__bu AAAAVPMALVT---NTRRTLT----EQALHSIGRHYFAVTVCG-DEVPNG
MAB_2130|M.abscessus_ATCC_1997 AAEQMPMALVT---NTIRSLT----DQALKTIGTHWFTESVCG-DEVPAG
Mflv_3054|M.gilvum_PYR-GCK VAEGTPMALVT---NTNRHLA----DRALESIGRHYFSFTVCG-DEVPRG
Mvan_3473|M.vanbaalenii_PYR-1 AAERTPAALVT---NTQRGLT----ERALNSIGRHYFSVTVCA-DEVASG
MAV_1053|M.avium_104 QDLASRYALAAVSSSALKRLAGCFSATGLDPLIPASVRFSAEDSLPVPTS
. .: * : .
MMAR_0580|M.marinum_M KPDPQGYLLAADALRVNIGSTIVFEDSPAGIRAGIASNALTVAIG--TL-
MUL_0545|M.ulcerans_Agy99 KPDPQGYLLAADALRVNIGSTIVFEDSPAGIRAGIASNALTVAIG--TL-
Mb3433|M.bovis_AF2122/97 KPAPDSFLRAAELLGVTPDAAAVFEDALSGVAAGRAGNFAVVVG------
Rv3400|M.tuberculosis_H37Rv KPAPDSFLRAAELLGVTPDAAAVFEDALSGVAAGRAGNFAVVVG------
MLBr_00393|M.leprae_Br4923 KPAPDSYLRGAQLLDVAPDAAAVFEDALSGVQAGLSGHFGFVVG------
MSMEG_4183|M.smegmatis_MC2_155 KPAPDPYLRAAELLGVPVARCLAVEDSVTGTTAAEAAGCPVLVIPNDVA-
TH_0959|M.thermoresistible__bu KPAPDIYHRAADLLGVAPEACLAVEDSPTGAAAAEGAGCPVLVVPNALE-
MAB_2130|M.abscessus_ATCC_1997 KPAPDPYLRAAALLGVEPRDCLAIEDSVTGAAAAEAAGCAVLVVPNHVE-
Mflv_3054|M.gilvum_PYR-GCK KPAPDPYLRAAELLALDPSDCLAVEDSVTGTAAAERAGCAVLVVPNDVP-
Mvan_3473|M.vanbaalenii_PYR-1 KPAPDPYLRAAELLGVDPADCLAVEDSVTGTAAAEKAGCAVLVVPNDVP-
MAV_1053|M.avium_104 KPDPAVYLHAGQVLGVAPEQGLAIEDSVAGVSSAVAAGYATVGNLMFVLP
** * : .. * : ..**: :* :. . :
MMAR_0580|M.marinum_M AAFDGHIERFENFHGFEVAGQPPAGGVILSMPAPMNCGV----
MUL_0545|M.ulcerans_Agy99 AAFDGHIERFENFHGFEVAGQPPAGGVILSMPAPMNCGV----
Mb3433|M.bovis_AF2122/97 INRTGRAAQAAQLRRHGADVVVTDLAELL--------------
Rv3400|M.tuberculosis_H37Rv INRTGRAAQAAQLRRHGADVVVTDLAELL--------------
MLBr_00393|M.leprae_Br4923 INRTGRVDQAEELRRIGANVVVTDLAELL--------------
MSMEG_4183|M.smegmatis_MC2_155 VPHGPRRKQVESLSLLGVDDLRAIHAELGPE---RLSA-----
TH_0959|M.thermoresistible__bu VQHSPRRRQIPSLTHVDVPLMREIHADLSAAPGPGVPAGHRPL
MAB_2130|M.abscessus_ATCC_1997 VPAGARRRHAASLSGLSVRDLRDAHADVLAATTCKPI------
Mflv_3054|M.gilvum_PYR-GCK VPGGLRRRHVQTLADLGPADLRRIHAEITRELGERTA------
Mvan_3473|M.vanbaalenii_PYR-1 VPGGLRRRHVGSLAGLDVADLRRIYAEIDRELRERTA------
MAV_1053|M.avium_104 DERDCRRAELIDAGAVAITDSWRALADVLLSSAVPAAGSSLA-
: . . :