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LGLPEKVRACLFDLDGVLTDTASVHTKAWKAMFDAYLSERAERTGGQFVPFDPAADYRQYVDGKKREDGV RSFLSSRGIQLPDGSPDDPGDLETVYGLGNRKNDMFQKVLKKDGVDVFEGSRRYLEAVSAAGLSIAVVSS SANTRDPSTCTMANCSPMSAFSICVPRRVPALLISRLVSWGIVD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0908 | - | - | 100% (185) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3433 | - | 2e-70 | 85.03% (147) | hydrolase |
| M. gilvum PYR-GCK | Mflv_1072 | - | 4e-45 | 60.67% (150) | beta-phosphoglucomutase family hydrolase |
| M. tuberculosis H37Rv | Rv3400 | - | 2e-70 | 85.03% (147) | hydrolase |
| M. leprae Br4923 | MLBr_00393 | - | 8e-65 | 76.19% (147) | putative hydrolase |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1144 | - | 1e-81 | 100.00% (147) | hydrolase |
| M. avium 104 | MAV_4350 | - | 1e-72 | 88.44% (147) | beta-phosphoglucomutase hydrolase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2142 | - | 1e-56 | 71.92% (146) | PROBABLE HYDROLASE |
| M. vanbaalenii PYR-1 | Mvan_5751 | - | 2e-47 | 66.44% (146) | beta-phosphoglucomutase family hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3433|M.bovis_AF2122/97 MANWYRPN-YPEVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMF
Rv3400|M.tuberculosis_H37Rv MANWYRPN-YPEVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMF
MUL_0908|M.ulcerans_Agy99 ----------------MLGLPEKVRACLFDLDGVLTDTASVHTKAWKAMF
MMAR_1144|M.marinum_M ----------------MLGLPEKVRACLFDLDGVLTDTASVHTKAWKAMF
MAV_4350|M.avium_104 MVEWIPPDPNHRKRVPVLGLPEKVHACLFDLDGVLTDTASVHTKAWKAMF
MLBr_00393|M.leprae_Br4923 MANWDHPTSKVRS--TVLGLPEQVRACLFDLDGVLTDTASVHAKAWQTMF
Mflv_1072|M.gilvum_PYR-GCK ------------MKGDMLGLPDRIHACLFDLDGVLTDTASVHRRAWKAMF
Mvan_5751|M.vanbaalenii_PYR-1 ----------------MLGLPDRIRACLFDLDGVLTDTASVHRRAWKAMF
TH_2142|M.thermoresistible__bu ----------------VLGLPDHIRACLFDLDGVLTDTAGVHRKAWKAMF
:****::::**************.:* :**::**
Mb3433|M.bovis_AF2122/97 DAYLAERAERTG---EKFVPFDPAADYHTYVDGKKREDGVRSFLSSRAIE
Rv3400|M.tuberculosis_H37Rv DAYLAERAERTG---EKFVPFDPAADYHTYVDGKKREDGVRSFLSSRAIE
MUL_0908|M.ulcerans_Agy99 DAYLSERAERTG---GQFVPFDPAADYRQYVDGKKREDGVRSFLSSRGIQ
MMAR_1144|M.marinum_M DAYLSERAERTG---GQFVPFDPAADYRQYVDGKKREDGVRSFLSSRGIQ
MAV_4350|M.avium_104 DAYLADRAKRTG---ETFVPFDPAADYRKYVDGKKREDGVRSFLQSRGIH
MLBr_00393|M.leprae_Br4923 DTYLYQRAKHTG---ENFVPFDPTADYRQYVDGKKREDGVRSFLGSRGIT
Mflv_1072|M.gilvum_PYR-GCK DEYLSDIADGAEDPDARYTPFDAGADYETYVDGKPRADGIRSFLGSRLID
Mvan_5751|M.vanbaalenii_PYR-1 DEYLRSRAEDG----VPYVPFDAGADYERYVDGKPRLDGIRSFLGSRGIV
TH_2142|M.thermoresistible__bu DEYLRDRAARTG---AEFVPFDIDADYHHYVDGKKREDGVRSFLASRSIK
* ** . * :.*** ***. ***** * **:**** ** *
Mb3433|M.bovis_AF2122/97 IPDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSRRYLEAVTA
Rv3400|M.tuberculosis_H37Rv IPDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSRRYLEAVTA
MUL_0908|M.ulcerans_Agy99 LPDGSPDDPGDLETVYGLGNRKNDMFQKVLKKDGVDVFEGSRRYLEAVSA
MMAR_1144|M.marinum_M LPDGSPDDPGDLETVYGLGNRKNDMFQKVLKKDGVDVFEGSRRYLEAVSA
MAV_4350|M.avium_104 LPDGSPDDAGDAETIYGLGNRKNDMFQKVLKQDGVKVFDGSRRYLEAASA
MLBr_00393|M.leprae_Br4923 LPEGSADNSGDVETIYGLGNRKDDLFRQVLKEHGIEVFDGSRRYLEAITY
Mflv_1072|M.gilvum_PYR-GCK VDE---------ATVTRLGDRKNEMFRKTLKSDGIEVFDGSRRYLQAAAD
Mvan_5751|M.vanbaalenii_PYR-1 APD---------ETVTLLGDRKNHVFTQTLHTDGVTVFEGSRRYLQAAAA
TH_2142|M.thermoresistible__bu LPDGHYDDDPATETVHGLGNRKNVVFHQILEAEGVEVFEGSRRYLAAVVD
: *: **:**: :: : *. .* **:****** *
Mb3433|M.bovis_AF2122/97 AGLGVAVVSSSANTRDVLATTGLDRFVQQRVDGVTLREEHIAGKPAPDSF
Rv3400|M.tuberculosis_H37Rv AGLGVAVVSSSANTRDVLATTGLDRFVQQRVDGVTLREEHIAGKPAPDSF
MUL_0908|M.ulcerans_Agy99 AGLSIAVVSSSANTRDPSTCT-----------------------------
MMAR_1144|M.marinum_M AGLSIAVVSSSANTRDVLEITGLGRFIQQRVDGVRLREEHIAGKPAPDSY
MAV_4350|M.avium_104 AGLGIAVVSSSANTRDVLEVTGLDRFVQQRVDGITLREEHLAGKPAPDSF
MLBr_00393|M.leprae_Br4923 AGLGVAVVSSSTNTRDVLKITGLDRFVQQQVDGITLREEHIAGKPAPDSY
Mflv_1072|M.gilvum_PYR-GCK AGLRRAVVSSSANTREVLELTGLDRYVEVRVDGVTLREENLPGKPAPDTY
Mvan_5751|M.vanbaalenii_PYR-1 AGLRRAVVSSSANTRTILELTGLDVYVEARVDGVTLREEHLPGKPAPDAF
TH_2142|M.thermoresistible__bu AGLGVAVVTSSANGRQILEVTGLDRFVQYRVDGVTMREEQLPGKPAPDSF
*** ***:**:* * *
Mb3433|M.bovis_AF2122/97 LRAAELLGVTPDAAAVFEDALSGVAAGRAGNFAVVVGINRTGRAAQAAQL
Rv3400|M.tuberculosis_H37Rv LRAAELLGVTPDAAAVFEDALSGVAAGRAGNFAVVVGINRTGRAAQAAQL
MUL_0908|M.ulcerans_Agy99 -----MANCSP---------MS----------AFSICVPRRV---PALLI
MMAR_1144|M.marinum_M LRGAQLLDTAPDAAAVFEDAISGVQAGRAGNFGYVVGVDRVG---QAEDL
MAV_4350|M.avium_104 LRGAQLLDVPAGAAAVFEDALSGVAAGRAGNFGFVVGVDRVG---QAEDL
MLBr_00393|M.leprae_Br4923 LRGAQLLDVAPDAAAVFEDALSGVQAGLSGHFGFVVGINRTGRVDQAEEL
Mflv_1072|M.gilvum_PYR-GCK LRAAELLGVDPAEAAVFEDALSGVAAGRAGDFGLVVGVDRTG---QAQAL
Mvan_5751|M.vanbaalenii_PYR-1 LRAAELLGVAPADAAVFEDALSGVAAGRAGGFGLVVGVDRTG---QSEAL
TH_2142|M.thermoresistible__bu LRAAELLQVPPQHGAVFEDALSGVAAGRAGGFGLVVGVDRVG---QAEAL
: . :* . : : * : :
Mb3433|M.bovis_AF2122/97 RRHGADVVVTDLAELL--
Rv3400|M.tuberculosis_H37Rv RRHGADVVVTDLAELL--
MUL_0908|M.ulcerans_Agy99 SR----LVSWGIVD----
MMAR_1144|M.marinum_M RRNGADVVITDLAELLQS
MAV_4350|M.avium_104 RRNGADVVVSDLAELLAS
MLBr_00393|M.leprae_Br4923 RRIGANVVVTDLAELL--
Mflv_1072|M.gilvum_PYR-GCK RDKGADIVITDLGELLT-
Mvan_5751|M.vanbaalenii_PYR-1 RRNGADIVVTDLGELLSP
TH_2142|M.thermoresistible__bu RRNGADIVVTDLAELLTP
:* .: :