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NFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAP YAGWLGSVAAQAVAVAGQARAAVAAFEAALAATVDPAAVAVNRMAMRALAMSNLLGQNAAAIAAVEAEYE LMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLNALFAGPAKMLRLNAGLGNVGNYNVGLG NVGIFNLGAANVGAQNLGAANAGSGNFGFGNIGNANFGFGNSGLGLPPGMGNIGLGNAGSSNYGLANLGV GNIGFANTGSNNIGIGLTGDNLTGIGGLNSGTGNLGLFNSGTGNIGFFNSGTGNFGVFNSGSYNTGVGNA GTASTGLFNVGGFNTGVANVGSYNTGSFNAGNTNTGGFNPGNVNTGWLNTGNTNTGIANSGNVNTGAFIS GNFSNGVLWRGDYEGLWGLSGGSTIPAIPIGLELNGGVGPITVLPIQILPTIPLNIHQTFSLGPLVVPDI VIPAFGGGTAIPISVGPITISPITLFPAQNFNTTFPVGPFFGLGVVNISGIEIKDLAGNVTLQLGNLNID TRINQSFPVTVNWSTPAVTIFPNGISIPNNPLALLASASIGTLGFTIPGFTIPAAPLPLTIDIDGQIDGF STPPITIDRIPLNLGASVTVGPILINGVNIPATPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGSSGWWN QAQTEVAGAGSGFANFGSLGSGVLNFGSGVSGLYNTGGLPPGTPAVVSGIGNVGEQLSGLSSAGTALNQS LIINLGLADVGSVNVGFGNVGDFNLGAANIGDLNVGLGNVGGGNVGFGNIGDANFGLGNAGLAAGLAGVG NIGLGNAGSGNVGFGNMGVGNIGFGNTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNVGLFNSG TGNFGLFNSGSFNTGIGNGGTGSTGLFNAGNFNTGVANPGSYNTGSFNVGDTNTGGFNPGSINTGWFNTG NANTGVANSGNVDTGALMSGNFSNGILWRGNFEGLFGLNVGITIPEFPIHWTSTGGIGPIIIPDTTILPP IHLGLTGQANYGFAVPDIPIPAIHIDFDGAADAGFTAPATTLLSALGITGQFRFGPITVSNVQLNPFNVN LKLQFLHDAFPNEFPDPTISVQIQVAIPLTSATLGGLALPLQQTIDAIELPAISFSQSIPIDIPPIDIPA STINGISMSEVVPIDVSVDIPAVTITGTRIDPIPLNFDVLSSAGPINISIIDIPALPGFGNSTELPSSGF FNTGGGGGSGIANFGAGVSGLLNQASSPMVGTLSGLGNAGSLASGVLNSGVDISGMFNVSTLGSAPAVIS GFGNLGNHVSGVSIDGLLAMLTSGGSGGSGQPSIIDAAIAELRHLNPLNIVNLGNVGSYNLGFANVGDVN LGAGNLGNLNLGGGNLGGQNLGLGNLGDGNVGFGNLGHGNVGFGNSGLGALPGIGNIGLGNAGSNNVGFG NMGLGNIGFGNTGTNNLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTGNIGFFNTGTGNWGLFNSGSYNTG IGNSGTGSTGLFNAGSFNTGLANAGSYNTGSLNAGNTNTGGFNPGNVNTGWFNAGHTNTGGFNTGNVNTG AFNSGSFNNGALWTGDHHGLVGFSYSIEITGSTLVDINETLNLGPVHIDQIDIPGMSLFDIHELVNIGPF RIEPIDVPAVVLDIHETMVIPPIVFLPSMTIGGQTYTIPLDTPPAPAPPPFRLPLLFVNALGDNWIVGAS NSTGMSGGFVTAPTQGILIHTGPSSATTGSLALTLPTVTIPTITTSPIPLKIDVSGGLPAFTLFPGGLNI PQNAIPLTIDASGVLDPITIFPGGFTIDPLPLSLALNISVPDSSVPIIIVPPTPGFGNATATPSSGFFNS GAGGVSGFGNFGAGSSGWWNQAHAALAGAGSGVLNVGTLNSGVLNVGSGISGLYNTAIVGLGTPALVSGA GNVGQQLSGVLAAGTALTQSPIINLGLADVGNYNLGLGNVGDFNLGAANLGDLNLGLGNIGNANVGFGNI GHGNVGFGNSGLGAALGIGNIGLGNAGSTNVGLANMGVGNIGFANTGTNNLGIGLTGDNQTGIGGLNSGA GNIGLFNSGTGNIGFFNSGTGNWGLFNSGSFNTGIGNSGTGSTGLFNAGGFTTGLANAGSYNTGSFNVGD TNTGGFNPGSINTGWFNTGNANTGIANSGNVDTGALMSGNFSNGILWRGNYEGLFSYSYSLDVPRITILD AHFTGAFGPVVVPPIPVLAINAHLTGNAAMGAFTIPQIDIPALNPNVTGSVGFGPIAVPSVTIPALTAAR AVLDMAASVGATSEIEPFIVWTSSGAIGPTWYSVGRIYNAGDLFVGGNIISGIPTLSTTGPVHAVFNAAS QAFNTPALNIHQIPLGFQVPGSIDAITLFPGGLTFPANSLLNLDVFVGTPGATIPAITFPEIPANADGEL YVIAGDIPLINIPPTPGIGNTTTVPSSGFFNTGAGGGSGFGNFGANMSGWWNQAHTALAGAGSGIANVGT LHSGVLNLGSGLSGIYNTSTLPLGTPALVSGLGNVGDHLSGLLASNVGQNPITIVNIGLANVGNGNVGLG NIGNLNLGAANIGDVNLGFGNIGDVNLGFGNIGGGNVGFGNIGDANFGFGNSGLAAGLAGMGNIGLGNAG SGNVGWANMGLGNIGFGNTGTNNLGIGLTGDNQSGIGGLNSGTGNIGLFNSGTGNIGFFNSGTANFGLFN SGSYNTGIGNSGVASTGLVNAGGFNTGVANAGSYNTGSFNAGDTNTGGFNPGSTNTGWFNTGNANTGVAN AGNVNTGALITGNFSNGILWRGNYEGLAGFSFGYPIPLFPAVGADVTGDIGPATIIPPIHIPSIPLGFAA IGHIGPISIPNIAIPSIHLGIDPTFDVGPITVDPITLTIPGLSLDAAVSEIRMTSGSSSGFKVRPSFSFF AVGPDGMPGGEVSILQPFTVAPINLNPTTLHFPGFTIPTGPIHIGLPLSLTIPGFTIPGGTLIPQLPLGL GLSGGTPPFDLPTVVIDRIPVELHASTTIGPVSLPIFGFGGAPGFGNDTTAPSSGFFNTGGGGGSGFSNS GSGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGTLGLVTSAFVSGFMNVGQQLSGLL FAGTGP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3347c | PPE55 | - | 100% (3157) | PPE FAMILY PROTEIN |
M. tuberculosis H37Rv | Rv3350c | PPE56 | 0.0 | 67.17% (3019) | PPE family protein |
M. tuberculosis H37Rv | Rv3343c | PPE54 | 0.0 | 46.38% (2721) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3380c | PPE55a | 0.0 | 99.46% (2044) | hypothetical protein Mb3380c |
M. gilvum PYR-GCK | Mflv_0325 | - | 3e-27 | 38.29% (175) | PPE protein |
M. leprae Br4923 | MLBr_01182 | - | 4e-31 | 45.29% (170) | PPE-family protein |
M. abscessus ATCC 19977 | MAB_0669 | - | 1e-26 | 36.05% (172) | PPE-family protein |
M. marinum M | MMAR_0642 | - | 0.0 | 35.78% (3027) | PPE family protein |
M. avium 104 | MAV_4704 | - | 3e-52 | 61.14% (175) | PPE family protein |
M. smegmatis MC2 155 | MSMEG_0619 | - | 2e-27 | 39.43% (175) | PPE family protein |
M. thermoresistible (build 8) | TH_3113 | - | 2e-30 | 40.93% (193) | PUTATIVE PPE protein |
M. ulcerans Agy99 | MUL_0965 | - | 1e-134 | 36.63% (991) | PPE family protein |
M. vanbaalenii PYR-1 | Mvan_0415 | - | 1e-28 | 38.29% (175) | PPE protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv3347c|M.tuberculosis_H37Rv ----------MN---FPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEE Mb3380c|M.bovis_AF2122/97 ----------MN---FPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEE MMAR_0642|M.marinum_M ----------MN---FAVLPPEINSARLTIGAGLGPMLEAANAWQGLAGE MUL_0965|M.ulcerans_Agy99 ----------MN---FIMLPPEINSARIFAGAGVGPTLAAAAAWDALAAD MAV_4704|M.avium_104 ----------MTNPHFAWLPPEVNSALIYSGPGPGPLLAAAAAWDGLAEE MLBr_01182|M.leprae_Br4923 ------------MFDFAALSPETNSTRMYLGPGSSPILTAAAAWVVLAKE Mflv_0325|M.gilvum_PYR-GCK MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAE Mvan_0415|M.vanbaalenii_PYR-1 ----------MSSPVWMALPPEVHSALLSSGPGPGSMLAAAATWQSLSAE MSMEG_0619|M.smegmatis_MC2_155 ----------MTAPIWMALPPEVHSSLLSSGPGPGSLLAAAGAWQSLSAE MAB_0669|M.abscessus_ATCC_1997 ----------MTAPIWMAEPPEVHSALLSAGPGPGAVLAAAVQWQEIGNN TH_3113|M.thermoresistible__bu ----------------MALPPEVHSTLLRTGPGPGALSAAADAWRMLSDE .** :* : *.* .. *. * :. : Rv3347c|M.tuberculosis_H37Rv LGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPYAGWLGSVAAQAVAVA Mb3380c|M.bovis_AF2122/97 LGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPYAGWLGSVAAQAVAVA MMAR_0642|M.marinum_M LGSAASAFSSVTTDLVSGGWQGAASTAMASAAAPYLKWLTTAAAQAGQAA MUL_0965|M.ulcerans_Agy99 LASAAQSFAAITVGLVGEAWQGAAATAMAAAARPYASWLGTAAARAAVTA MAV_4704|M.avium_104 LASSAQSFSSVTSDLASGSWQGASSAAMMTVANQYVSWLSAAAAQAEEVS MLBr_01182|M.leprae_Br4923 LTAAAQGLQSAVEALLT-TFEGESAAALAERVTPYEKWLTQNAASAELTA Mflv_0325|M.gilvum_PYR-GCK YASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPYLAWLAQQSAVSAATA Mvan_0415|M.vanbaalenii_PYR-1 YAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPYLAWLAQQSAAGAAAA MSMEG_0619|M.smegmatis_MC2_155 YAAAAAELTSVLSAVQAGSWEGPSSEQYVAAHAPYLQWLAQQSANSAAAA MAB_0669|M.abscessus_ATCC_1997 YANTAVELAQVLAGVRAGSWQGPSASEYVAAHLPYLAWLEQAAAESSVIA TH_3113|M.thermoresistible__bu YRAAAVELAAVVSQTCATAWEGVGADAYAAAHGPYLFWLTDTAAAAAAAG :* : ::* .: * ** :* . . Rv3347c|M.tuberculosis_H37Rv GQARAAVAAFEAALAATVDPAAVAVNRMAMRALAMSNLLGQNAAAIAAVE Mb3380c|M.bovis_AF2122/97 GQARAAVAAFEAALAATVDPAAVAVNRMAMRALAMSNLLGQNAAAIAAVE MMAR_0642|M.marinum_M TQVRLAAAAFEAALAATVHPAAISANRSQFVSLVVSNLLGQNAPAIAAAE MUL_0965|M.ulcerans_Agy99 AQANAAAAVFEAAQAATAHPELVAANRNQLVSLVVSNLFGQNAPAIASTE MAV_4704|M.avium_104 HQASAIATAFEVALAATVQPAVVAANRALVQALAATNWLGQNTPAIADIE MLBr_01182|M.leprae_Br4923 TQLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKE Mflv_0325|M.gilvum_PYR-GCK VQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGTNFLGINTIPIALNE Mvan_0415|M.vanbaalenii_PYR-1 AQHEAAAAAYSTALATMPTLPELALNHTTHAVLVATNFLGINTIPIAMTE MSMEG_0619|M.smegmatis_MC2_155 VQHETAAAAYSTALATMPTMAELALNHTMHGVLVATNFFGINTIPIALNE MAB_0669|M.abscessus_ATCC_1997 AQHETTAAAYNSALAAMPTLAELAANHITHGVLVGTNFFGINTIPIALNE TH_3113|M.thermoresistible__bu AQLEAAAAAHASALAAMPTMAELTANRTTHAALVATNFFGVNTIPIAVNE * . .. * : : *: * :* :* *: .** * Rv3347c|M.tuberculosis_H37Rv AEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLNALF Mb3380c|M.bovis_AF2122/97 AEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLNAIF MMAR_0642|M.marinum_M AAYEQMWAQDVAAMFGYRSGAESIAAALTPFPL----------------- MUL_0965|M.ulcerans_Agy99 AAYDQLWAQDVAAMAGYHSGASAVAAQLAPW------------------- MAV_4704|M.avium_104 AAYEQMWASDVAAMFGYHADASAAVAKLPPW------------------- MLBr_01182|M.leprae_Br4923 AEYTEMWIQDAAAMTSYQASVLEAVGATKAFTAP---------------- Mflv_0325|M.gilvum_PYR-GCK ADYVRMWIQAATTMATYQSVSGAALAATPTSAP----------------- Mvan_0415|M.vanbaalenii_PYR-1 ADYVRMWIQAATTMATYQAVSGAALAATPTATP----------------- MSMEG_0619|M.smegmatis_MC2_155 ADYVRMWIQAATTMSTYQAVSGAAVAAAPVSAP----------------- MAB_0669|M.abscessus_ATCC_1997 ADYVRMWVQAAATMSAYQATTEAMTSAIPPTQQ----------------- TH_3113|M.thermoresistible__bu ADYARMWIQAATTMATYEAVASAAVSATPRTVA----------------- * * :* .::* *.: . Rv3347c|M.tuberculosis_H37Rv AGPAKMLRLNAGLGNVGNYNVGLGNVGIFNLGAANVGAQNLGAANAGSGN Mb3380c|M.bovis_AF2122/97 AGPAKMLRLNAGLGNVGNYNVGLGNVGIFNLGAANVGAQNLGAANAGSGN MMAR_0642|M.marinum_M ----------QAAGSVVTANLGFANVGFRNFGNGNVGDYNLGSGNLGSEN MUL_0965|M.ulcerans_Agy99 ------------------------QQALRTLQN----------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv FGFGNIGNANFGFGNSGLGLPPGMGNIGLGNAGSSNYGLANLGVGNIGFA Mb3380c|M.bovis_AF2122/97 FGFGNIGNANFGFGNSGLGLPPGMGNIGLGNAGSSNYGLANLGVGNIGFA MMAR_0642|M.marinum_M VGSSNIGSGNIGFGNSGPALTAALNNIGFGNTGSNNIGFGNTGNNNIGFG MUL_0965|M.ulcerans_Agy99 ----RVAGATTALPPPGPAAAAALP-------GAAAVGFP---------- MAV_4704|M.avium_104 ----NEVLQNLGFSNASTAVTRPAG------SGAVARGYT---------- MLBr_01182|M.leprae_Br4923 --PLGVNEVGLAQEVVEEVVEEVVEEVVEAEQAISQAALD---------- Mflv_0325|M.gilvum_PYR-GCK ----APSVLLPGVGEAGRAAADMSAFAAQPMAAQAGAAFD---------- Mvan_0415|M.vanbaalenii_PYR-1 ----APFVLAPGVGEAGRAAADVTAFAAQAQAAEAGSALD---------- MSMEG_0619|M.smegmatis_MC2_155 ----APFLLKPGVGEAGSASASVQQMSAQATAAESGSSLD---------- MAB_0669|M.abscessus_ATCC_1997 ----PPAILSPG-GEARSDQSDVPGSPDQIMKMLQG-------------- TH_3113|M.thermoresistible__bu ----PPPILGAGTGESATAAITGAHVTAELRAAESRTLLD---------- . Rv3347c|M.tuberculosis_H37Rv NTGSNNIGIGLTGDNLTGIGGLNSGTGNLGLFNSGTGNIGFFNSGTGNFG Mb3380c|M.bovis_AF2122/97 NTGSNNIGIGLTGDNLTGIGGLNSGTGNLGLFNSGTGNIGFFNSGTGNFG MMAR_0642|M.marinum_M NTGDNNRGIGLTGTGQFGLGGLNSGSGNIGLFNSGTGNFGIGNSGTGNWG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv VFNSG-SYNTGVGNAGTASTGLFNVGGFNTGVANVGSYNTGSFNAGNTNT Mb3380c|M.bovis_AF2122/97 VFNSG-SYNTGVGNAGTASTGLFNVGGFNTGVANVGSYNTGSFNAGNTNT MMAR_0642|M.marinum_M IGNSGNSYNTGIGNSGDANTGFFNAGVANTGIGNVGSYNTGGFNPGDANT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv GGFNPGNVNTGWLNTGNTNTGIANSGNVNTGAFISGNFSNGVLWRGDYEG Mb3380c|M.bovis_AF2122/97 GGFNPGNVNTGWLNTGNTNTGIANSGNVNTGAFISGNFSNGVLWRGDYEG MMAR_0642|M.marinum_M GGFNTGSYNTGYLNRGDYNTGVANFGNVNTGALNTGDYNNGFLWRGDNQG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv -LWGLSGGSTIPAIPIGLELNGGVGPITVLPIQILPTIPLNIHQTFSLGP Mb3380c|M.bovis_AF2122/97 -LWGLSGGSTIPAIPIGLELNGGVGPITVLPIQILPTIPLNIHQTFSLGP MMAR_0642|M.marinum_M LIFGEPGFGNSTTVPSSGFFNSGEGSASGFFNSGANNSGFFNDSSGPIGN MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv LVVPDIVIPAFGGGTAIPISVGPITISPITLFPAQNFNTTFPVG------ Mb3380c|M.bovis_AF2122/97 LVVPDIVIPAFGGGTAIPISVGPITISPITLFPAQNFNTTFPVG------ MMAR_0642|M.marinum_M SGFANTGVLQSGLVNSGNTISGLLNSSLVPITTPAYISGVLNTGSNLAGF MUL_0965|M.ulcerans_Agy99 ---------------------------------------VLHIG------ MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv ----PFFGLGVVNISGIEIKDLAGNVTLQLG--------------NLNID Mb3380c|M.bovis_AF2122/97 ----PFFGLGVVNISGIEIKDLAGNVTLQLG--------------NLNID MMAR_0642|M.marinum_M LLGPTLFNIGFANDGVGNILAHANVGNYNIGGNGNVGDYNIFGSGNAGSY MUL_0965|M.ulcerans_Agy99 -------NIGFANLSVG------NIGDYNLG------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv TRINQSFPVTVNWSTP-------------AVTIFPNGISIPNNPLALLAS Mb3380c|M.bovis_AF2122/97 TRINQSFPVTVNWSTP-------------AVTIFPNGISIPNNPLALLAS MMAR_0642|M.marinum_M NIFGSGNIGSLNLGSGNFGGTNFGSGNIGSLNLGSANIGSYNIGSASLGS MUL_0965|M.ulcerans_Agy99 ----SGNTGSFNLGSG-------------------------NIGDASLGS MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv --ASIGTLGFTIPGFTIPAAPLPLTIDIDGQIDGFSTPPITIDRIPLNLG Mb3380c|M.bovis_AF2122/97 --ASIGTLGFTIPGFTIPAAPLPLTIDIDGQIDGFSTPPITIDRIPLNLG MMAR_0642|M.marinum_M YNVGFGNLGDYNTGFGNAGSYNQGLANTGSNNAGFANTGNGNIGIGLTGD MUL_0965|M.ulcerans_Agy99 -----GNAGDSNVGFG----------NFGSNNVGIGNNGNNNIGIGLNGD MAV_4704|M.avium_104 -----------------------------SRIAGFLAPRAPQ-------- MLBr_01182|M.leprae_Br4923 ----------------------------QAVNEGMEATVVPQVDQQVNVD Mflv_0325|M.gilvum_PYR-GCK ---------VSNIIADIIRLYGEVLRFLFEPIFNFLRDPIGNTFALITDF Mvan_0415|M.vanbaalenii_PYR-1 ---------LSNIIADLIRAYGELLRFLFEPIFDFLRDPLGNTIKLITDF MSMEG_0619|M.smegmatis_MC2_155 ---------LSSIISDLLNQYLQGVPGG-QAILDFLKDPLGNLGRLLTDF MAB_0669|M.abscessus_ATCC_1997 --------------------------------FQQWFEKMG--------F TH_3113|M.thermoresistible__bu ---------EINELIDRLFAPLFPPGFADALPDGLLGTLLAPLLPGATGD Rv3347c|M.tuberculosis_H37Rv ASVTVGPILINGVNIPATPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGS Mb3380c|M.bovis_AF2122/97 ASVTVGPILINGVNIPATPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGS MMAR_0642|M.marinum_M GQIGIGALNSG----IGNAGLFNSGTD-NVGLFNSGSGNIG-IGNSGSGN MUL_0965|M.ulcerans_Agy99 DLIGIGALNSG----AGNLGFGNSGTN-NIGFFNSGDNNIG-FFNSGSG- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 VATPQTAVPDS--------------------------------------- Mflv_0325|M.gilvum_PYR-GCK LTNPVQALITWGP------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 LTNPAQALITWGP------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 MTNPAGALATWWP------------------------------------- MAB_0669|M.abscessus_ATCC_1997 NPATSAVLAVIML------------------------------------- TH_3113|M.thermoresistible__bu GPPMATIMSFLLMG------------------------------------ Rv3347c|M.tuberculosis_H37Rv SG-------------------------WWNQAQTEVAGAGSGFANFGSLG Mb3380c|M.bovis_AF2122/97 SG-------------------------WWNQAQTEVAGAGSGFANFGSLG MMAR_0642|M.marinum_M TGLLNAGVANWGLENPGTANTGIGNAGQYNTGLHNVGAANTGFYNNGSYN MUL_0965|M.ulcerans_Agy99 -----------------------------NFGFENAGDINTGFWNGRDTN MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv SGVLNFGSGVSGLYNTGGLPPG---------------------------- Mb3380c|M.bovis_AF2122/97 SGVLNFGSGVSGLYNTGGLPPG---------------------------- MMAR_0642|M.marinum_M TGGFNVGSTNTGSFDAGSANTGNFNPGDTNTGSYNPGNVNTGFFDTGNYN MUL_0965|M.ulcerans_Agy99 TG------------------------------------------------ MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M NGFFVTSDNQGQIAINLSVTTPHIPIDVQSIVPVNQVYTLGGNTIQVSEA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M GSVFPRTYYLGGLFFLGPINLGASTLTIPTVTIALGGPSTNIPISIVGAV MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M ESRTITFLDIPAAPGFGNTTAGPSSGFFNAGTGGNSGFANFGAASSGLWN MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv ---TPAVVSGIGNVGEQLSGLSSAGTALN--------------------- Mb3380c|M.bovis_AF2122/97 ---TPAVVSGIGNVGEQLSGLSSAGTALN--------------------- MMAR_0642|M.marinum_M SGVAAAGNSGVQNFGSLASGWANLGNTLSGFYNTSTANLAAPANLSGLFN MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv ------------QSLIINLGLADVGSVNVGFGNVGDFNLGAANIGDLNVG Mb3380c|M.bovis_AF2122/97 ------------QSLIINLGLADVGSVNVGFGNVGDFNLGAANIGDLNVG MMAR_0642|M.marinum_M VGTDLAGVLRDANGTILNLGLADLGHLNVGSGNVGDFNVGSANIGSANFG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv LGNVGGGNVGFGNIGDANFGLGNAGLAAGLAGVGNIGLGNAGSGNVGFGN Mb3380c|M.bovis_AF2122/97 LGNVGGGNVGFGNIGDANFGLGNAGLAAGLAGVGNIGLGNAGSGNVGFGN MMAR_0642|M.marinum_M FGNVGSDNLGSGNIGSGNIGFGNAGARLTDA-FNNIGFGNTGDNNIGFGN MUL_0965|M.ulcerans_Agy99 -----------------------------------------------FGN MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv MGVGNIGFGNTGTNNLGIGLTGDNQTG---IGGLNSGAGNIGLFNSGTGN Mb3380c|M.bovis_AF2122/97 MGVGNIGFGNTGTNNLGIGLTGDNQTG---IGGLNSGAGNIGLFNSGTGN MMAR_0642|M.marinum_M TGNGNFGFGNTGNGNIGIGLTGAGQRGVNFAGGLNSGSGNIGLFNSGTNN MUL_0965|M.ulcerans_Agy99 SGLSNFGFG-----------------------------------NSGVNN MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv VGLFNSGTGNFGLFNSGSFNTGIGNGGTGSTGLFNAGNFNTGVANPGSYN Mb3380c|M.bovis_AF2122/97 VGLFNSGTGNFGLFNSGGYNTGIGNGGTGSTGLFNAGNFNTGVANPGSYN MMAR_0642|M.marinum_M VGIGNSGTGNWGIGNSGSLNTGFGNAGSTNTGLFNTGMVNTGIANVGDYN MUL_0965|M.ulcerans_Agy99 VGAGNGGSSNVGLGNAGLLNT-------------------------GSFN MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv TGSFNVGDTNTGGFNPGSINTGWFNTGNANTGVANSGNVDTGALMSGNFS Mb3380c|M.bovis_AF2122/97 TGSFNVGDTNTGGFNPGSINTGWFNTGNANTGVANSGTVNTGAFITGNDS MMAR_0642|M.marinum_M TGWFNTGDVNTGAANRGDYNTGWYNTGNYSTGFANAGNIDTGLLISGDMG MUL_0965|M.ulcerans_Agy99 SGKFNTGDFNSGSMN-----TGYFNSSGHNTGLGNSG------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv NGILWRGNFEGLFGLNVGITIPEFPIHWTSTGGIGPIIIPDTTILP---- Mb3380c|M.bovis_AF2122/97 NGILWRGNFEGLFGLNVGITIPEFPIHWTSTGGIGPIIIPDTTILP---- MMAR_0642|M.marinum_M NGFAWRGDQQGQVSASYVIHVPEIPAHVDASAPINIPLTANFTNTLYSGI MUL_0965|M.ulcerans_Agy99 -----------------------------------------FTN------ MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M TMEDINFGFTVAIGPLPVLTGTIDSVTLAPITATGPAISFNIGDPKGTTV MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv ---------------------------------PIHLG------------ Mb3380c|M.bovis_AF2122/97 ---------------------------------PIHLG------------ MMAR_0642|M.marinum_M VSIPATASLGPVDWTIFDIPAVTGLFNSTSSPSSGFFNGGTGTVSGIANF MUL_0965|M.ulcerans_Agy99 ---------------------------------TGFFN------------ MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv ----------------------------------LTGQANYGFAVPDIPI Mb3380c|M.bovis_AF2122/97 ----------------------------------LTGQANYGFAVPDIPI MMAR_0642|M.marinum_M GGDISGFQNFGTSALSGFKNVGSLQSGLLNIGDTVSGLFNTGIGTPANVS MUL_0965|M.ulcerans_Agy99 -----------------------------------SGDLNTGMGSPEDQS MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv PAIHIDFD------------------------------------------ Mb3380c|M.bovis_AF2122/97 PAIHIDFD------------------------------------------ MMAR_0642|M.marinum_M GVSNIGTTLAGIFVDQASGMSTFSLGLADIGQANVGFGNTGDFNLGFANL MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv -----GAADAGFT------------------------------------- Mb3380c|M.bovis_AF2122/97 -----GAADAGFT------------------------------------- MMAR_0642|M.marinum_M GDENLGLGNSGFNNLGLANLGNFNVGSANLGGYNIGSSNLGDYNVGFGNA MUL_0965|M.ulcerans_Agy99 ------VANSGFR------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv ------------------------------------------APATTLLS Mb3380c|M.bovis_AF2122/97 ------------------------------------------ASATTLLS MMAR_0642|M.marinum_M GGFNQGLANSGNNNIGLFNTGNNNIGIGLTGDNQQGFNFGGGLNSGTGNT MUL_0965|M.ulcerans_Agy99 -------------------------------------------NAGSGNS MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv ALGITGQFRFGPITVSNVQLNPFNVNLKLQFLHDAFPNEFPDPTISVQIQ Mb3380c|M.bovis_AF2122/97 ALGITGQFRFGPITVSNVQLNPFNVNLKLQFLHDAFPNEFPDPTISVQIQ MMAR_0642|M.marinum_M GLFNSGTNNTGIFNSGTNNTGIFNSGNANWGIGNTGV-TNTGVFNSGQIN MUL_0965|M.ulcerans_Agy99 GFNNTGSFSSGFFNSTNSNSEFLNAG--------------------GTVN MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 ------------------------------------------------SS Mflv_0325|M.gilvum_PYR-GCK ------------------------------------------FLLAVVYQ Mvan_0415|M.vanbaalenii_PYR-1 ------------------------------------------FLAAVAYQ MSMEG_0619|M.smegmatis_MC2_155 ------------------------------------------FLFGVAYQ MAB_0669|M.abscessus_ATCC_1997 ------------------------------------------FLYDLLWY TH_3113|M.thermoresistible__bu -------------------------------------LSNPAYLFPVLVY Rv3347c|M.tuberculosis_H37Rv VAIPLTSATLGGLALPLQQTIDAIELPAISFSQSIPIDIPP--------- Mb3380c|M.bovis_AF2122/97 VAIPLTSATLGGLALPLQQTIDAIELPAISFSQSIPIDIPP--------- MMAR_0642|M.marinum_M TGLWNAGNVNTGIGNPGNYNTGSFNTGSFNTAGLNPGDYNTGYLNSGNYN MUL_0965|M.ulcerans_Agy99 SGINNSGNTNAGIGNLGDDNFGLFNNGTFNTG------------------ MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 AAAPQLWGGFAQHLSPINDTLSMINN------------------------ Mflv_0325|M.gilvum_PYR-GCK A----VSWVGASILYPSLFLLPLLATT----------------------- Mvan_0415|M.vanbaalenii_PYR-1 A----VSWVGASILYPSLLLLPLVATT----------------------- MSMEG_0619|M.smegmatis_MC2_155 VFFNLVGWPTWGMIFASPFLIPALAALG---------------------- MAB_0669|M.abscessus_ATCC_1997 P---------YYASYLLPFLIPALSGLS---------------------- TH_3113|M.thermoresistible__bu LLFTGVVHTTVAVSGMLAQLVPLMPALLPVAV------------------ Rv3347c|M.tuberculosis_H37Rv ------------IDIPASTINGISMS----EVVPIDVSVDIPAVTITGTR Mb3380c|M.bovis_AF2122/97 ------------IDIPASTINGISMS----EVVPIDVSVDIPAVTITGTR MMAR_0642|M.marinum_M TGFANSGDVNTGAFISGNYSNGLLWRGDYQGLWGIDYAITIPDTAIPLNL MUL_0965|M.ulcerans_Agy99 ---------------AGNSSGGAVFP------------------------ MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv IDPIPLNFDVLSSAG----------------------------------- Mb3380c|M.bovis_AF2122/97 IDPIPLNFDVLSSAG----------------------------------- MMAR_0642|M.marinum_M DVPVYLDIPITGTLGVFTVDGFTIPASTVELDIVGIGFKAVHVSAIKFPN MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv -----------------------------PINISIIDIPALPGFGNSTEL Mb3380c|M.bovis_AF2122/97 -----------------------------PINISIIDIPALPGFGNSTEL MMAR_0642|M.marinum_M LELGLPAIDINIGTGPEPLIHIVGTGGLLPIKIPIIDIAAAPGFGNSTTT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv PSSGFFNTGGGGGSGIANFGAGVSGLLNQASSPMVGTLSGLGNAGSLASG Mb3380c|M.bovis_AF2122/97 PSSGFFNTGGGGGSGIANFGAGVSGLLNQASSPMVGTLSGLGNAGSLASG MMAR_0642|M.marinum_M ASSGFFNTGSGTASGFGNTGGNNSGFFNLASGSSG--ISGYQNLGDLVSG MUL_0965|M.ulcerans_Agy99 YTSGLFNSGNGSS------------------------------------G MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -----------------------------------------------LAI Mvan_0415|M.vanbaalenii_PYR-1 -----------------------------------------------LAI MSMEG_0619|M.smegmatis_MC2_155 ----------------------------------------------ITGL MAB_0669|M.abscessus_ATCC_1997 ----------------------------------------------GLAA TH_3113|M.thermoresistible__bu ---------------------------------------------AALGG Rv3347c|M.tuberculosis_H37Rv VLNSGVDISGMFNVSTLG-SAPAVISGFGNLGNHVSGVSIDGLLAMLTSG Mb3380c|M.bovis_AF2122/97 VLNSGVDISGMFNVSTLG-SAPAVISGFGNLGNHVSGVSIDGLLAMLTSG MMAR_0642|M.marinum_M MSNLGNSVSGFFNTSSLGVSIPADISGAANIGTNIAGFFNDNPIGNLGIA MUL_0965|M.ulcerans_Agy99 VFNAGDEQSGFFGTSGLVLTGTDGLAATTTSGLPAL----DLPAPNLGIG MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK VAGVGQHLLSLLNTPPAEEAAEEPAPAQSAPSRPDQQSFPATMSAPPPPS Mvan_0415|M.vanbaalenii_PYR-1 VLGVGAYLLENLPAPAEDAPAEEPAASSPAPTRADQPSPAIAVSAPPPPS MSMEG_0619|M.smegmatis_MC2_155 VLLIDHVLNNPVDVPAEDEAPQEVAAAP----RTDQP-LAVGISPAGVPG MAB_0669|M.abscessus_ATCC_1997 LMHLRPAAPGPVPA-AALSPGDRPIRRPTQHVEPNLAALPLPTSSVVPSG TH_3113|M.thermoresistible__bu LAGVWAGLSGLAGLAGLTAVPAADGGASAAPVPAGGPSLPSGSSAPPAPT Rv3347c|M.tuberculosis_H37Rv GSGGSGQPSIIDAAIAELRHLNPLNIVNLGNVGSYNLGFANVGDVNLGAG Mb3380c|M.bovis_AF2122/97 GSGGSGQPSIIDAAIAELRHLNPLNIVNLGNVGSYNLGFANVGDVNLGAG MMAR_0642|M.marinum_M NLGNGN--------------------IGDGNIGSNNAGFGNVGANNFGSG MUL_0965|M.ulcerans_Agy99 NAGVGN--------------------LGLGNIGDYNLGSGNTGDANFGSG MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 ------------------------------HAGMANAGLSLVNGMGSAMK Mflv_0325|M.gilvum_PYR-GCK GAPIAAN--------------------TVSAGSPPAPGAPAAAAATFVPY Mvan_0415|M.vanbaalenii_PYR-1 SAAATVG--------------------TVATGTAPAPGAPAAATASFVPY MSMEG_0619|M.smegmatis_MC2_155 SAATAAA--------------------PAPAPAGTTVAAPAPAAATFVPY MAB_0669|M.abscessus_ATCC_1997 GSSVPVS--------------------TPTAPAHTVSSVPAPSAA--ISY TH_3113|M.thermoresistible__bu G-SAAPT--------------------TGTAPGGAGSPPPAGHSVPPAPH Rv3347c|M.tuberculosis_H37Rv NLGNLNLGGGNLGGQNLGLGNLGDGNVGFGNLGHGNVGFGNSGLG----A Mb3380c|M.bovis_AF2122/97 NLGNLNLGGGNLGGQNLGLGNLGDGNVGFGNLGHGNVGFGNSGLG----A MMAR_0642|M.marinum_M NIGSFNFLSGNHGTYNFGLGNLGDYNVGLANLGDYNVGFGNAGSLNQGFA MUL_0965|M.ulcerans_Agy99 NIGALNLGSGNHG------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 SLAPT--------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK VVAGRDP-YEGFS------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 AVAGRDP-GTGFS------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 AVANRDP-GEGFT------------------------------------- MAB_0669|M.abscessus_ATCC_1997 AIPGLVPPGVSFG------------------------------------- TH_3113|M.thermoresistible__bu SAPPVGTSGPPYL------------------------------------- Rv3347c|M.tuberculosis_H37Rv LPGIGNIGLGNAGSNNVGFG---------------NMGLGNIGFGNTGTN Mb3380c|M.bovis_AF2122/97 LPGIGNIGLGNAGSNNVGFG---------------NMGLGNIGFGNTGTN MMAR_0642|M.marinum_M NTGDHNIGIGNTGNNNIGIGLTGDNQVGINLAGGLNSGTGNAGLFNSGTN MUL_0965|M.ulcerans_Agy99 ---DANLGFGNTGDNNIGL------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv NLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTGNIGFFNTGTGNWGLFNSG Mb3380c|M.bovis_AF2122/97 NLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTGNIGFFNTGTGNWGLFNSG MMAR_0642|M.marinum_M NTGIFNSGTGNTGI--FNSGTANWGIGNSGTANSGIANSGSTNWGLWNPG MUL_0965|M.ulcerans_Agy99 ----FNSGDNNVGF--FNSGGANFGLANSGDTNTGLWNAGSTNTGFGNAG MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -----TTKAAESAFKAMGSAVQSTGRGLLGSSSGGHVTAQLGRAASIGSL Mflv_0325|M.gilvum_PYR-GCK -----PTVRDSTGAKAPAGTIPAAASGIAASAAERRKRRRRQKEEIKGRG Mvan_0415|M.vanbaalenii_PYR-1 -----PTVRDSTSAKAPASGIPAAASGVAASAAERRKRRRRQKDEIAGRA MSMEG_0619|M.smegmatis_MC2_155 -----PTLGNKSQVAAPASGVPAAASGVAASLASRRKRRRKKGAQIEERG MAB_0669|M.abscessus_ATCC_1997 -----PKSTEKSSESAVDTVAAVAAARGAVAAQARRRLRGKNKAEAGGR- TH_3113|M.thermoresistible__bu -----IAAQPAPGVARRSAGARRAASIVEPAGSAAAAAAARESAPIRRRR Rv3347c|M.tuberculosis_H37Rv SYNTGIGNSGTGSTGLFNAGSFNTGLANAGSYNTGSLNAGNTNTGGFNPG Mb3380c|M.bovis_AF2122/97 SYNTGIGNSGTGSTGLFNAGSFNTGLANAGSYNTGSLNAGNTNTGGFNPG MMAR_0642|M.marinum_M TGNTGIANAGDYNTGLYNAGHTNTGLANPTDYNTGFFNTGDYNTGLANAG MUL_0965|M.ulcerans_Agy99 SADFGFGNAGDRNMGFGNAGAANMGAGNSGSYNTGSFNSGTLNTGDFNGG MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 RVPQTWTTASQPVTAATRALSPARVAVATESESAPLLGGGLPMAPMVPGG Mflv_0325|M.gilvum_PYR-GCK YADAYADYEELPDDGPPEQPAPRVTASTRGAGPMGFAGTVSRGD-EQAGG Mvan_0415|M.vanbaalenii_PYR-1 YADAYADYEPEPDDEPPVRQEPRIAATERGAGPMGFAGTVSRDA-AQAGG MSMEG_0619|M.smegmatis_MC2_155 YADAYMDYEE-PDEDPAPQPEPRVRASERGSDAMGFTGTVTRHD-VTAAG MAB_0669|M.abscessus_ATCC_1997 -RHEYLEETAGMGAT-ATADVPAYAATGRGTGPLGFAGTAPAAASTHVAA TH_3113|M.thermoresistible__bu GQKDGLHGHRHEHQQPASMS-AATAPSAAGIRVLGGAGRISRTR-GSVPH Rv3347c|M.tuberculosis_H37Rv NVNTGWFNAGHTNTGGFNTGNVNTGAFNSGSFNNGALWTGDHHGLVGFSY Mb3380c|M.bovis_AF2122/97 NVNTGWFNAGHTNTGGFNTGNVNTAAFNSGSFNNGALWTGDHHGLVGFSY MMAR_0642|M.marinum_M NYNTGFFNTGDYNTGLANTGDVNTGAFISGNYSNGMFWRGDYQGLVGAHY MUL_0965|M.ulcerans_Agy99 DHNTGWGNSGNTNTGGINSGDLNT-------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 GSGTGGVNTALRLQPRAFVMPRNPAAG----------------------- Mflv_0325|M.gilvum_PYR-GCK LTTLAGDSFGGGPREPMLPGTWDPDATDDRHTDGRDGHDGHDGKEKP--- Mvan_0415|M.vanbaalenii_PYR-1 LTTLPGDPFGGGPKAPMLPGTWDPDTEPD------ERHNHHDGKDSQ--- MSMEG_0619|M.smegmatis_MC2_155 LTTLTGDTFDDRPVTPMLPGTWDGDENPAP------SPDDPEGGPRR--- MAB_0669|M.abscessus_ATCC_1997 TVRLSSD--EARQVIPMLPSTWDAD-----------------GGDQN--- TH_3113|M.thermoresistible__bu AEITPGDPTEPSSPTDRAHRPAEPN------------------------- Rv3347c|M.tuberculosis_H37Rv SIEITGSTLVDINETLNLGPVHIDQIDIPGMSLFDIHELVN----IGPFR Mb3380c|M.bovis_AF2122/97 SIEITGSTLVDINETLNLGPVHIDQIDIPGMSLFDIHELVN----IGPFR MMAR_0642|M.marinum_M EIFIPEFPVLNFDLNIPVDIPIYLDLGSLALNGFTIPTITIDALSITDFK MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv IEPIDVP---AVVLDIHETMVIPPIVFLPSMTIGGQTYTIPLDTPPAPAP Mb3380c|M.bovis_AF2122/97 IEPIDVP---AVVLDIHETMVIPPIVFLPSMTIGGQTYTIPLDTPPAPAP MMAR_0642|M.marinum_M IGPITIPTIKGILPVIDINIGNPDGSSSIPIAIRSGLGPISIVLLDIPAA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv PPFRLPLLFVNALGDNWIVGASNSTGMSGGFVTAPTQGILIHTGPS---- Mb3380c|M.bovis_AF2122/97 PPFRLPLLFVNALGDNWIVGASNSTGMSGGFVTAPTQGILIHTGPS---- MMAR_0642|M.marinum_M PGFGNSTSAPSSGFFNSGTGTASGFGNVGANNSGFWNTGFGDIGSSGLQN MUL_0965|M.ulcerans_Agy99 -GFGSS-------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv --SATTGSLALTLPTVTIPTITTSPIPLKIDVSGGLPAFTLFPGGLNIPQ Mb3380c|M.bovis_AF2122/97 --SATTGSLALTLPTVTIPTITTSPIPLKIDVSGGLPAFTLFPGGLNIPQ MMAR_0642|M.marinum_M YGQQLSGWANLGNTVSGWYNSSTADLPTAANLSGFFNIGTELSGVLRDSA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv NAIP-LTIDASGVLDPITIFPGGFTIDPLP---LSLALNISVPDSSVPII Mb3380c|M.bovis_AF2122/97 NAIP-LTIDASGVLDPITIFPGGFTIDPLP---LSLALNISVPDSSVPII MMAR_0642|M.marinum_M GTIFNAGLGDLGQLNLGSGNVGDFNVGSANIGSFNVGFGNVGADNLGSGN MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv IVPPTPGFGNATATPSSGFFN----SGAGGVSGFGNFGAGSSGWWNQAHA Mb3380c|M.bovis_AF2122/97 IVPPTPGFGNATATPSSGFFN----SGAGGVSGFGNFGAGSSGWWNQAHA MMAR_0642|M.marinum_M IGSGNIGFGNAGAGLTEAFNNIGFGNVGDTNIGFGNTGNGNLGFGNTGNG MUL_0965|M.ulcerans_Agy99 ------------------------ADQAVTNSGFGNNGSGNSGFNNTG-- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv ALAG--AGSGVLNVGTLNSGVLNVGSGISGLYNTAIVGLGTPALVSGAGN Mb3380c|M.bovis_AF2122/97 ALAG--AGSGVLNVGTLNSGVLNVGSGISGLYNTAIVGLGTPALVSGAGN MMAR_0642|M.marinum_M NIGIGLSGDGQIGFGPLNDGVGNAGLFNLGDFNTGLANAGNDNQGW--SN MUL_0965|M.ulcerans_Agy99 ------------------------------DTNSGFHNANTS-------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv VGQQLSGVLAAGTALTQSPIINLGLADVGNYNLGLGNVGDFNLGAANLGD Mb3380c|M.bovis_AF2122/97 VGQQLSGVLAAGTALTQSPIINLGLADVGNYNLGLGNVGDFNLGAANLGD MMAR_0642|M.marinum_M TGNNNIGLFNTGDNNVGIGLTGDGRVGFGSLSSGAGNTGFFNSGTSNAGM MUL_0965|M.ulcerans_Agy99 ------ALFS-------------------------GHSGLLNAG------ MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv LNLGLGNIGNANVGFGNIGHGNVGFGNSGLG-AALGIGNIGLGNAGSTNV Mb3380c|M.bovis_AF2122/97 LNLGLGNIGNANVGFGNIGHGNVGFGNSGLG-RRS----------ASAIS MMAR_0642|M.marinum_M FNSGTGNVGFFNSGTGNVGIGNMGTGGIGIGLQGDNLVGIGGLNSGSFNV MUL_0965|M.ulcerans_Agy99 -------------GSQSVGIN----------------------NTGSFNT MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv GLANMGVGNIGFANTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTG Mb3380c|M.bovis_AF2122/97 GWAMRAAPTLAWP------------------------------------- MMAR_0642|M.marinum_M GLFNSGTGNVGIGNSGTG-------------------------------- MUL_0965|M.ulcerans_Agy99 VLFNTGFRTAGIANSATN-------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv NIGFFNSGTGNWGLFNSGSFNTGIGNSGTGSTGLFNAGGFTTGLANAGSY Mb3380c|M.bovis_AF2122/97 ----------TWVWATSGSPTPAPTTSGLGWP-------ATTRPASAA-- MMAR_0642|M.marinum_M ----------NWGIGNSGSHNSGIGNTGSYNTGLFNSGSFNTGIANPGNF MUL_0965|M.ulcerans_Agy99 ----------GLLTATSGVANSGNNSSGGFN-------------ANPD-- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv NTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGIANSGNVDTGALMSGNF Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M NTGLFNIGVFNTGIANPGDYNTGFYNTGDYNTGLANIGNFDTGAFITGNM MUL_0965|M.ulcerans_Agy99 --------------------QSGFFN------------------------ MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv SNGILWRGNYEGLFSYSYSLDVPRITILDAHFTGAFGPVVVPPIPVLAIN Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M ANGVFWRADSMGQLSAHYAITVNRIPAFMTIDAPVNIPITG--------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv AHLTGNAAMGAFTIPQIDIPALNPNVTGSVGFGPIAVPSVTIPALTAARA Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M ------------TITDISIPAVTFPKVPATGKVDLAIISG---------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv VLDMAASVGATSEIEPFIVWTSSGAIGPTWYSVGRIYNAGDLFVGGNIIS Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv GIPTLSTTGPVHAVFNAASQAFNTPALNIHQIPLGFQVPGSIDAITLFPG Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M ------------------------------------TVIAPIGPITIHGG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv GLTFPANSLLNLDVFVGTPGATIPAITFPEIPANADGELYVIAGDIPLIN Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M DASAPLNTPIVIDFGTQPALQLNLGNPDGSTVVHVGGYFNFGPGQIPLID MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv IPPTPGIGNTTTVPSSGFFNTGAGGGSGFGNFGANMSGWWNQAHTALAGA Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M IKPAAGFFNATTGPSSGFFNLGDGSASGFANVGANNSGIWNVATAALG-- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv GSGIANVGTLHSGVLNLGSGLSGIYNTSTLPLGTPALVSGLGNVGDHLSG Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M NSGFQNIGSQQSGLANLGNAISGFLNTG---GATPANLSGFQNIGTDLAG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv LLASNVGQNPITIVNIGLANVGNGNVGLGNIGNLNLGAANIGDVNLGFGN Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M WYRNGPDATTFSFG---IANPGFWNVGSANIGSYNLGNANIGVSNFGFGN MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv IGDVNLGFGNIGGGNVGFGNIGDANFGFGNSGLAAGLAGMGNIGLGNAGS Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M LGSANLGSANLGGFNLGSANIGSHNFGFANTGPALSDA-IGNIGFGNTGS MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv GNVGWANMGLGNIGFGNTGTNNLGIGLTGDNQSGIGGLNSGTGNIGLFNS Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M YNIGFGNTGNGNLGFANTGDGNIGIGLAGDTMTGFGGWNSGSGNIGLFNS MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv GTGNIGFFNSGTANFGLFNSGSYNTGIGNSGVASTGLVNAGGFNTGVANA Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M GTNNIGFGNSGTGNWGIGNSGSYNTGIGNTGTTNTGFFNSGMVNTGIGNA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv G----------SYNTGSFNAGDTNTGGFNPGSTNTGWFNTGNANTGVANA Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M GNYNTGCYNTGDFNTGSFNPGDYNTGGFNPGNYNTGYFNEGNSNTGLANS MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv GNVNTGALITGNFSNGILWRGNYEGLAGFSFGYPIPLFPAVGADVTGDIG Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M GNVNTGAFISGNYSNGLLWRGDYQGLLGFTYESTVPAIPWNIGVHS---- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv PATIIPPIHIPSIPLGFAAIGHIGPISIPNIAIPSIHLGIDPTFDVGPIT Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M -------------DIDIPITGAINTITQDMFTIAEFEIPISLETTICLIY MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv VDPITLTIPGLSLDAAVSEIRMTSGSSSGFKVRPSFSFFAVGPDGMPGGE Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M VPFVGCVLH----------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv VSILQPFTVAPINLNPTTLHFPGFTIPTGPIHIGLPLSLTIPGFTIPGGT Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M ---------VSVTVPITTEHVGPFVIDPSVINPQSPINTAIT-------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv LIPQLPLGLGLSGGTPPFDLPTVVIDRIPVELHASTTIGPVSLPIFGFGG Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M ---------------------------DTIDFSDAGTVGPATFGFN-WQQ MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv APGFGNDTTAPSSGFFNTGGGGGSGFSNSGSGMSGVLN-------AISDP Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M SPGFFNSSDTPSSGFFNSGAGGASGLLNDAQGAVSGIGNAFLESSGFFNA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv LLGSASGFANFGTQLSGILNRGAGISGVYNTGTLGLVTSAFVSGFMNVGQ Mb3380c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0642|M.marinum_M GGPGLSGLQNVGTLESGWANFGNSLSGIYNTSILNLMAQAFVSGLGNTGH MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- Rv3347c|M.tuberculosis_H37Rv QLSGLLFAGTGP Mb3380c|M.bovis_AF2122/97 ------------ MMAR_0642|M.marinum_M ELSGFLNDAMA- MUL_0965|M.ulcerans_Agy99 ------------ MAV_4704|M.avium_104 ------------ MLBr_01182|M.leprae_Br4923 ------------ Mflv_0325|M.gilvum_PYR-GCK ------------ Mvan_0415|M.vanbaalenii_PYR-1 ------------ MSMEG_0619|M.smegmatis_MC2_155 ------------ MAB_0669|M.abscessus_ATCC_1997 ------------ TH_3113|M.thermoresistible__bu ------------