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LPEIPIAAPDLLGHGRSPWAAPWTIDANVSALAALLDNQGDGPVVVVGHSFGGAVAMHLAAARPDQVAAL VLLDPAVALDGSRVREVVDAMLASPDYLDPAEARAEKATGAWADVDPPVLDAELDEHLVALPNGRYGWRI SLPAMVCYWSELARDIVLPPVGTATTLVRAVRASPAYVSDQLLAALDKRLGADFELLDFDCGHMVPQAKP TEVAAVIRSRLGPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3203 | lipV | - | 100% (224) | POSSIBLE LIPASE LIPV |
| M. tuberculosis H37Rv | Rv0045c | - | 4e-09 | 27.07% (229) | hydrolase |
| M. tuberculosis H37Rv | Rv2715 | - | 1e-06 | 40.58% (69) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3228 | lipV | 1e-128 | 100.00% (224) | lipase LipV |
| M. gilvum PYR-GCK | Mflv_4667 | - | 5e-80 | 64.25% (221) | alpha/beta hydrolase fold |
| M. leprae Br4923 | MLBr_02603 | - | 7e-05 | 35.90% (78) | hypothetical protein MLBr_02603 |
| M. abscessus ATCC 19977 | MAB_3517 | - | 2e-74 | 59.73% (221) | putative hydrolase, alpha/beta fold LipV |
| M. marinum M | MMAR_1355 | lipV | 1e-102 | 80.54% (221) | lipase LipV |
| M. avium 104 | MAV_4150 | - | 1e-87 | 67.86% (224) | hydrolase, alpha/beta fold family protein |
| M. smegmatis MC2 155 | MSMEG_1940 | - | 2e-74 | 60.36% (222) | hydrolase, alpha/beta fold family protein |
| M. thermoresistible (build 8) | TH_0447 | lipV | 1e-88 | 69.37% (222) | POSSIBLE LIPASE LIPV |
| M. ulcerans Agy99 | MUL_2524 | lipV | 1e-102 | 81.00% (221) | lipase LipV |
| M. vanbaalenii PYR-1 | Mvan_1800 | - | 3e-78 | 64.25% (221) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4667|M.gilvum_PYR-GCK ---------------MTEQLCTYRFGPAGPARVLAIHGLTGHGKRWESLF
Mvan_1800|M.vanbaalenii_PYR-1 ---------------MTDLLCTYRFGPPGPARVLAIHGLTGHGKRWETLF
Rv3203|M.tuberculosis_H37Rv --------------------------------------------------
Mb3228|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1355|M.marinum_M ---------------MSTDLHVHRYGPEEPVRVLTIHGVTEHGQSWEYLA
MUL_2524|M.ulcerans_Agy99 ---------------MSTDLHVHRYGPEEPVRVLTIHGVTEHGQSWEYLA
MAV_4150|M.avium_104 ---------------MTATLHVHRYGPPGPARILALHGLTGHGQRWQHLA
TH_0447|M.thermoresistible__bu ---------------------VYRYGPAGPPRLLAIHGLTGHGRRWQTLA
MSMEG_1940|M.smegmatis_MC2_155 ------------------MLHVHRYGPAGAAQVLLIHGLTGHGQRWQTLA
MAB_3517|M.abscessus_ATCC_1997 ---------------MTPTLNIHRYGPVEPARLLALHGLTGHGRRWAPLF
MLBr_02603|M.leprae_Br4923 MTITRTERNFYGVGGVRIVYDVWMPDTRPRAVIILAHGFGEHARRYDHVA
Mflv_4667|M.gilvum_PYR-GCK TR-HLSDIPAVAPDLVGHGRSS-----WDAPWTIEANVAALTALLDAEAE
Mvan_1800|M.vanbaalenii_PYR-1 TR-HLPDVTALAPDLLGHGRSS-----WDAPWTIDANVAALAALVDAEAD
Rv3203|M.tuberculosis_H37Rv ----MPEIPIAAPDLLGHGRSP-----WAAPWTIDANVSALAALLDNQGD
Mb3228|M.bovis_AF2122/97 ----MPEIPIAAPDLLGHGRSP-----WAAPWTIDANVSALAALLDNQGD
MMAR_1355|M.marinum_M G--YLPEVSIAAPDLLGHGRSS-----WAAPWSIDANVSALAALLKDQAD
MUL_2524|M.ulcerans_Agy99 G--YLPEVNIAAPDLLGHGRSS-----WAAPWSIDANVSALAALLKDQAD
MAV_4150|M.avium_104 G--LLPEFAWAAPDLVGHGRSS-----WSAPWTIDANISALADLLDAQAG
TH_0447|M.thermoresistible__bu TR-HLPEIAVAAPDLIGHGRSS-----WAAPWTFEANVGALVALLEDQAD
MSMEG_1940|M.smegmatis_MC2_155 TE-HLPEVGVLAPDLIGHGRSS-----WAAPWTIDANVAALAALLDR---
MAB_3517|M.abscessus_ATCC_1997 DE-YLADVPVLAPDLLGHGRSP-----ATAPWSLEAHADAVAAELDTAET
MLBr_02603|M.leprae_Br4923 HYFAAAGLATYALDLRGHGRSAGKRVLVRDLSEYNADFDILVGIATRDHP
. . * ** *****. :*. :.
Mflv_4667|M.gilvum_PYR-GCK GPVVVVG-HSFGGAIALNLAAARPDLIAGLVLLDPAVGLDGRWMREIADE
Mvan_1800|M.vanbaalenii_PYR-1 GPVVVVG-HSFGGAIALNLAAVRPDLVAGLVLLDPAVALDGRWMREVADD
Rv3203|M.tuberculosis_H37Rv GPVVVVG-HSFGGAVAMHLAAARPDQVAALVLLDPAVALDGSRVREVVDA
Mb3228|M.bovis_AF2122/97 GPVVVVG-HSFGGAVAMHLAAARPDQVAALVLLDPAVALDGSRVREVVDA
MMAR_1355|M.marinum_M GPVVVVG-HSFGGAVALQLAAAHPDLVAALILLDPAIGLNGSRVREVVDA
MUL_2524|M.ulcerans_Agy99 GPVVVVG-HSFGGAVALQLAAAHPDLVAALILLDPAIGLDGSRVREVVDA
MAV_4150|M.avium_104 APVLVVG-HSFGAGLAMHLAAVRPDRVAGLLLLDPAIGLDGAWMREIAEA
TH_0447|M.thermoresistible__bu GPVVVVG-HSFGGAVAMHLAAARPDLVAGLVLLDPAIGLDGEWMREIAES
MSMEG_1940|M.smegmatis_MC2_155 -PTLVVG-HSFGGALALNLSAAHPDLVSGLVLLDPAIGLDGEWMRDIADD
MAB_3517|M.abscessus_ATCC_1997 GPIVVVG-HSFGGAIALHLAARRPDLVKSLVLLDPAIGLDGDWMRQIADQ
MLBr_02603|M.leprae_Br4923 GLKRIVAGHSMGGAIVFAYGVERPDNYDLMVLSGPAVAAQD--MVSPLRA
:*. **:*..:.: .. :** ::* .**:. :. : .
Mflv_4667|M.gilvum_PYR-GCK MYTSPDYTDREEARQEKIGGSWGEVAEDELDRELDEHLVASAGGRVGWRI
Mvan_1800|M.vanbaalenii_PYR-1 MYNSPDYTDREEARQEKIGGSWGEVAEDELDRELDEHLVEQTDGRVGWRI
Rv3203|M.tuberculosis_H37Rv MLASPDYLDPAEARAEKATGAWADVDPPVLDAELDEHLVALPNGRYGWRI
Mb3228|M.bovis_AF2122/97 MLASPDYLDPAEARAEKATGAWADVDPPVLDAELDEHLVALPNGRYGWRI
MMAR_1355|M.marinum_M MVAFPDYTDPAEARMERAYGAWADVDPAVLDAELDEHLITLPNGRYSWRI
MUL_2524|M.ulcerans_Agy99 MVAFPDYTDPAEARMERAYGAWADVDPAVLDAELDEHLITLPNGRYSWRI
MAV_4150|M.avium_104 MLASPDYPDAEEARLEKLHGSWSDVEPALLDAEIDEHLIELPNGRYGWRV
TH_0447|M.thermoresistible__bu MLASPDYPDREEARTEKFTGSWADVEPAELDRDLDEHLIALPGGRFGWRI
MSMEG_1940|M.smegmatis_MC2_155 MLSSPDYPDREEARLDKVNGSWGEVDPAEVERELDEHLVEVGEGRVGWRI
MAB_3517|M.abscessus_ATCC_1997 MVTYPDYTDRAEAKSDKVAGAWSDVPDHVIEAELDEHLIQLSNGRCGWRM
MLBr_02603|M.leprae_Br4923 VVGKGLGLVAPGLPVHQLEVDAISRNRAVVAAYKDDPLVYHGKVPAGVGR
: .: . : *: *: .
Mflv_4667|M.gilvum_PYR-GCK SIPAMLCYWSELTRPAVIPRDGTPTTLVRATRTDPPYAGDELVAALDAGL
Mvan_1800|M.vanbaalenii_PYR-1 SIPATLSYWSELTRAVPVPRDGTPTTLVRATHTDPPYASDELIATLDAGL
Rv3203|M.tuberculosis_H37Rv SLPAMVCYWSELARDIVLPPVGTATTLVRAVRASPAYVSDQLLAALDKRL
Mb3228|M.bovis_AF2122/97 SLPAMVCYWSELARDIVLPPVGTATTLVRAVRASPAYVSDQLLAALDKRL
MMAR_1355|M.marinum_M SLPAMVCYWSELARDAALPPPGIATTLVRAVRADPQYVSDELIAALRERL
MUL_2524|M.ulcerans_Agy99 SLPAMVCYWSELARDAALPPPGIATTLVRAVRADPQYVSDELIAALRERL
MAV_4150|M.avium_104 CLPAMMSYWSELARDPVLPPAQTATILVRAKRTAPPYVGDELIAALQDRL
TH_0447|M.thermoresistible__bu CVPAMMAYWSELARDVVLPPSGIPTTLVRAAWTDPPYVTGELLDGLSQRL
MSMEG_1940|M.smegmatis_MC2_155 SIPAAMSYWSELARPVVLPHNPIPTVLVRAKRCRPPFVADALIDGLTDRL
MAB_3517|M.abscessus_ATCC_1997 NLPAAVTAWSELARDIVLPVNVIRTTLLLATRTSPPYVLPKLLDALQATL
MLBr_02603|M.leprae_Br4923 VMLQVGETMTRRAPVLTTPLLVVHGSEDRLVLVDGSHRLVECVGSTDVEL
: :. : * . : *
Mflv_4667|M.gilvum_PYR-GCK GPNFTLLEWDCDHMVPLARPTETARLIRDLLP--
Mvan_1800|M.vanbaalenii_PYR-1 GASLTVLEWDCDHMVPLAKPAETAAAIRDRLV--
Rv3203|M.tuberculosis_H37Rv GADFELLDFDCGHMVPQAKPTEVAAVIRSRLGPR
Mb3228|M.bovis_AF2122/97 GADFELLDFDCGHMVPQAKPTEVAAVIRSRLGPR
MMAR_1355|M.marinum_M GADFALREFECGHMVPQAKPTEVATLIREQLKTP
MUL_2524|M.ulcerans_Agy99 GADFALREFECGHMVPQAKPTEVATLIREQLKTP
MAV_4150|M.avium_104 GSRFRLLDFDCNHMVPYAKPDDVAALARELLKAR
TH_0447|M.thermoresistible__bu GADLTLVDLDCLHMVAQAKPAETAELIRRHLG--
MSMEG_1940|M.smegmatis_MC2_155 GSKFTLLDWDCDHMVAQAKPAETAELIRRQLG--
MAB_3517|M.abscessus_ATCC_1997 GSQFELIDIDCDHMVSQSRPAETAAAIRSHLE--
MLBr_02603|M.leprae_Br4923 KVYPGLYHEVFNEPERDQVLEDVVCWILKRL---
: . . :.. *