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PRSNSMTAEPAPTDLRRSRGDRQRDAIVTAVRELLHERPFAELSVSTISERAGVARSGFYFYFDSKYAVL AVIIAEAMAELDQLTHSFGPRDEAESPSEFAKRMVGYAAIVFASNDPIMRACNLARSTDAQIREIMDDFQ NTVVEKIVGLVGRDAGARPISDDLPALVRVMIAVTSSTLAHDSAFVGRDGDPARALAVVERLWESSLWGG Q*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4314 | - | - | 100% (212) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0963 | - | 2e-14 | 27.23% (202) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3103 | - | 5e-13 | 30.92% (152) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3084c | - | 1e-53 | 52.79% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3058c | - | 1e-53 | 52.79% (197) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00064 | - | 5e-10 | 21.90% (210) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3422c | - | 2e-62 | 60.91% (197) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1635 | - | 3e-61 | 58.88% (197) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3926 | - | 3e-61 | 59.05% (210) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2290 | - | 1e-80 | 67.77% (211) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1635 | - | 1e-76 | 70.59% (204) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3401 | - | 2e-61 | 58.88% (197) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2032 | - | 2e-94 | 81.95% (205) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3084c|M.bovis_AF2122/97 ------MTSHAADEKQ-------AAPPMRRRGDRHRQAILRAARELLEE-
Rv3058c|M.tuberculosis_H37Rv ------MTSHAADEKQ-------AAPPMRRRGDRHRQAILRAARELLEE-
MMAR_1635|M.marinum_M -----MVNGQAADEKQ-------RGPTLRRRGDKQRQAILQAVRELLEE-
MUL_3401|M.ulcerans_Agy99 -----MVNGQAADEKQ-------RGPTLRRRGDKQRQAILQAVRELLEE-
MAV_3926|M.avium_104 ------MTSHPANPE----------PGARRRGDKQRQAILAAVRELLQE-
Mflv_4314|M.gilvum_PYR-GCK MPRSNSMTAEPAP-----------TDLRRSRGDRQRDAIVTAVRELLHE-
Mvan_2032|M.vanbaalenii_PYR-1 ------MTAEPAP-----------SDLRRSRGDRQRDAIIAAVRELLQE-
MSMEG_2290|M.smegmatis_MC2_155 ------MTAESVPQGSNGSAGATAAQARRSRGDRQREAIVAAVRELLEE-
TH_1635|M.thermoresistible__bu ------VTTDSP-----------AREDRRSRGDRQRDAIVAAVRELLEE-
MAB_3422c|M.abscessus_ATCC_199 ------MVSPARS-------------GTQTRGDRQRDAIMTAVAELIAEN
MLBr_00064|M.leprae_Br4923 -----MINSTAGQTSQ-----SRSRRSTRPSGDDRELAILATAEQLLED-
: . : ** :. **: :. :*: :
Mb3084c|M.bovis_AF2122/97 TPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQH
Rv3058c|M.tuberculosis_H37Rv TPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQH
MMAR_1635|M.marinum_M RPFAELSVATISNRAGVARSGFYFYFDSKYSVLAQLMAEAVEELEERTQY
MUL_3401|M.ulcerans_Agy99 RPFAELSVATISNRAGVARSGFYFYFDSKYSVLAQLMAEAVEELEERTQY
MAV_3926|M.avium_104 KPFAELSVSTISLRAGVARSGFYFYFDSKYAVLAQLMAEATEELEQLTQY
Mflv_4314|M.gilvum_PYR-GCK RPFAELSVSTISERAGVARSGFYFYFDSKYAVLAVIIAEAMAELDQLTHS
Mvan_2032|M.vanbaalenii_PYR-1 RAFADLSVSTISERAGVARSGFYFYFDSKYAVLAVIVAEAMAELDQLTHD
MSMEG_2290|M.smegmatis_MC2_155 QPFADISVSTISERAGVARSGFYFYFDSKYAVLAVILAEAMEELDALTHN
TH_1635|M.thermoresistible__bu RSFADLSVSTISERAGVARSGFYFYFDSKYAVLAVILGEAMEELDKLTQN
MAB_3422c|M.abscessus_ATCC_199 HSFADLSVSAISERAGVGRSGFYFYFDSKYSVLAQMVGDAFAELDELTHY
MLBr_00064|M.leprae_Br4923 RPLTEISVDYLAKSAGISRPTFYFYFASKEAVLLTLLDRVFNKANAALET
.::::** :: **:.*. ***** ** :** :: . : : .
Mb3084c|M.bovis_AF2122/97 FSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILE
Rv3058c|M.tuberculosis_H37Rv FSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILE
MMAR_1635|M.marinum_M FAPRQPGESPQEFAKRMVGSAAIVYTHNDPVMMACNAARHTDIEIRDILD
MUL_3401|M.ulcerans_Agy99 FAPRQPGESPQEFAKRMVGSAAIVYTHNDPVMMACNAARHTDIEIRDILD
MAV_3926|M.avium_104 FAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTACNEARHTDVEIRNLMD
Mflv_4314|M.gilvum_PYR-GCK FGPRDEAESPSEFAKRMVGYAAIVFASNDPIMRACNLARSTDAQIREIMD
Mvan_2032|M.vanbaalenii_PYR-1 FAPREPGESPSDFAKRMVGYAATVYARNDPIMGACNLARNTDAEIREIMD
MSMEG_2290|M.smegmatis_MC2_155 FAPRGENESPAAFAKRMVGSAAAVYATNDPVMSACTVAQNTDAQIRDIMN
TH_1635|M.thermoresistible__bu FAPRGAEETPAEFARRMVGSAAAVYASNDPVMRACSAAQNTDAQIREMMG
MAB_3422c|M.abscessus_ATCC_199 FAPRGEEETPEQFAHRMVGSAAASFAHNDPLMKACQEARITDPTIAGLLD
MLBr_00064|M.leprae_Br4923 LIKNRDNKRGNKWRTGIN-VFFETFGSHKAVTCAGQVTR-DNTEVRKLWS
: . : : : : :..: * :: : : :
Mb3084c|M.bovis_AF2122/97 RQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDAL
Rv3058c|M.tuberculosis_H37Rv RQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDAL
MMAR_1635|M.marinum_M QQFDVVLREIVGVIDAEMRAGTANPISEDLPTLIRTLTATTALMLTGDAL
MUL_3401|M.ulcerans_Agy99 QQFDVVLREIVGVIDAEMRAGTANPISEDLPTLIRTLTATTALMLTGDAL
MAV_3926|M.avium_104 QQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALMLTGDPV
Mflv_4314|M.gilvum_PYR-GCK DFQNTVVEKIVGLVG---RDAGARPISDDLPALVRVMIAVTSSTLAHDSA
Mvan_2032|M.vanbaalenii_PYR-1 DFQDSVIDKIVDLVG---RDSGARPVSQDLPALVRTLIAMTSMTLAHDSA
MSMEG_2290|M.smegmatis_MC2_155 DFEDATIAKIVGVIE---QDTGARPISDDLPALVRTLTATTAMTLSRDAG
TH_1635|M.thermoresistible__bu DLQAIVIDKIVGVIE---QDASAQPITDDLHALVRTLVATTALTLTHDSA
MAB_3422c|M.abscessus_ATCC_199 DLTDVVIEKILKIAETEVKERGAQPISDDLPALVRSLVALTASTVSGDSS
MLBr_00064|M.leprae_Br4923 TFMQKWISYTAAVIDAE-RKRGVAPDTLPATELATALNLMNERALFASFT
: : : . * : * : . : .
Mb3084c|M.bovis_AF2122/97 LVGPDSDAARRVRVLEQMWLNALWGGGKAP----
Rv3058c|M.tuberculosis_H37Rv LVGPDSDAARRVRVLEQMWLNALWGGGKAP----
MMAR_1635|M.marinum_M LVGRDSDLERRVRVLEQMWLNALWGGPIRT----
MUL_3401|M.ulcerans_Agy99 LVGRDSDLERRVRVLEQMWLNALWGGPIRT----
MAV_3926|M.avium_104 LTGPDSDRDRRVAVLEQLWLHALWAG--RP----
Mflv_4314|M.gilvum_PYR-GCK FVGRDGDPARALAVVERLWESSLWGGQ-------
Mvan_2032|M.vanbaalenii_PYR-1 FVGRGADPARAVEIVERLWLSSLWGGDSLETHKA
MSMEG_2290|M.smegmatis_MC2_155 FVGRDADPARAVEIVERLWLSALWGG--LPE---
TH_1635|M.thermoresistible__bu FVGRATDISRAVDVVERLWLYSLWGGGNLPER--
MAB_3422c|M.abscessus_ATCC_199 FVGRNTDPARAIATVETLWRVSLLGR--------
MLBr_00064|M.leprae_Br4923 AEQPHVPESRVLDTLVHIWVSSIYNEIR------
* : : :* ::