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VSIPENAIAVVGMAGRFPGAKDVSAFWSNLRRGKESIVTLSEQELRDAGVSDKTLADPAYVRRAPLLDGI DEFDAGFFGFPPLAAQVLDPQHRLFLQCAWHALEDAGADPARFDGSIGVYGTSSPSGYLLHNLLSHRDPN AVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVAVHLACLSLLSGECDMALAGG SSLCIPHRVGYFTSPGSMVSAVGHCRPFDVRADGTVFGSGVGLVVLKPLAAAIDAGDRIHAVIRGSAINN DGSAKMGYAAPNPAAQADVIAEAHAVSGIDSSTVSYVECHGTGTPLGDPIEIQGLRAAFEVSQTSRSAPC VLGSVKSNIGHLEVAAGIAGLIKTILCLKNKALPATLHYTSPNPELRLDQSPFVVQSKYGPWECDGVRRA GVSSFGVGGTNAHVVLEEAPAEASEVSAHAEPAGPQVILLSAQTAAALGESRTALAAALETQDGPRLSDV AYTLARRRKHNVTMAAVVHDREHAATVLRAAEHDNVFVGEAAHDGEHGDRADAAPTSDRVVFLFPGQGAQ HVGMAKGLYDTEPVFAQHFDTCAAGFRDETGIDLHAEVFDGTATDLERIDRSQPALFTVEYALAKLVDTF GVRAGAYIGYSTGEYIAATLAGVFDLQTAIKTVSLRARLMHESPPGAMVAVALGPDDVTQYLPPEVELSA VNDPGNCVVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHTSAMDPMLGQFQEFLSRQQLRPPRTPLLSN LTGSWMSDQQVVDPASWTRQISSPIRFADELDVVLAAPSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRL MRHPLQDVDDRDTFLRALGELWSAGVEVDWTPRRPAVPHLVSLPGYPFARQRHWVEPNHTVWAQAPGANN GSPAGTADGSTAATVDAARNGESQTEVTLQRIWSQCLGVSSVDRNANFFDLGGDSLMAISIAMAAANEGL TITPQDLYEYPTLASLTAAVDASFASSGLAKPPEAQANPAVPPNVTYFLDRGLRDTGRCRVPLILRLDPK IGLPDIRAVLTAVVNHHDALRLHLVGNDGIWEQHIAAPAEFTGLSNRSVPNGVAAGSPEERAAVLGILAE LLEDQTDPNAPLAAVHIAAAHGGPHYLCLAIHAMVTDDSSRQILATDIVTAFGQRLAGEEITLEPVSTGW REWSLRCAALATHPAALDTRSYWIENSTKATLWLADALPNAHTAHPPRADELTKLSSTLSVEQTSELDDG RRRFRRSIQTILLAALGRTIAQTVGEGVVAVELEGEGRSVLRPDVDLRRTVGWFTTYYPVPLACATGLGA LAQLDAVHNTLKSVPHYGIGYGLLRYVYAPTGRVLGAQRTPDIHFRYAGVIPELPSGDAPVQFDSDMTLP VREPIPGMGHAIELRVYRFGGSLHLDWWYDTRRIPAATAEALERTFPLALSALIQEAIAAEHTEHDDSEI VGEPEAGALVDLSSMDAG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2935 | ppsE | - | 100% (1488) | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE |
M. tuberculosis H37Rv | Rv1664 | pks9 | e-144 | 35.36% (1018) | polyketide synthase pks9 |
M. tuberculosis H37Rv | Rv2048c | pks12 | e-135 | 36.53% (906) | polyketide synthase pks12 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2960 | ppsE | 0.0 | 99.93% (1488) | phenolpthiocerol synthesis type-I polyketide synthase PPSE |
M. gilvum PYR-GCK | Mflv_3390 | - | 0.0 | 58.11% (1499) | beta-ketoacyl synthase |
M. leprae Br4923 | MLBr_02353 | - | 0.0 | 81.95% (1496) | polyketide synthase |
M. abscessus ATCC 19977 | MAB_2256 | - | 0.0 | 40.33% (1019) | polyketide synthase |
M. marinum M | MMAR_1772 | ppsE | 0.0 | 81.37% (1492) | phenolpthiocerol synthesis type-I polyketide synthase PpsE |
M. avium 104 | MAV_1763 | - | 1e-143 | 36.95% (939) | tylactone synthase modules 4 & 5 |
M. smegmatis MC2 155 | MSMEG_0408 | - | 1e-148 | 37.39% (952) | type I modular polyketide synthase |
M. thermoresistible (build 8) | TH_4458 | - | 1e-125 | 32.64% (1100) | PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide |
M. ulcerans Agy99 | MUL_2015 | ppsE | 0.0 | 80.97% (1492) | phenolpthiocerol synthesis type-I polyketide synthase PpsE |
M. vanbaalenii PYR-1 | Mvan_3123 | - | 0.0 | 59.33% (1485) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 MSTVEGLRDPASSFAIVGYAARFPGAADADEFWRVLAEGRDAVSEVPKDR MSMEG_0408|M.smegmatis_MC2_155 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDR TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 WDADEFFDPDPDAPGKVVTRRAGFVDDVTGFDAPFFGMSAREARLLDPQH MSMEG_0408|M.smegmatis_MC2_155 WDIEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQH TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 RLLLETAWRAVEHSGTAPTDLANTNTGVFIGISTHDYLGMASDELTYDQI MSMEG_0408|M.smegmatis_MC2_155 RILMETAWRAVEHSGIAPTSLANSNTGVFVGLATHDYLGMASDELTYPEI TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 EAYTAIGTSSAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL MSMEG_0408|M.smegmatis_MC2_155 EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 GECDLALAGGANVLLTPATMITFSQAHMLAPDGRCKTFDAAADGYVRGEG MSMEG_0408|M.smegmatis_MC2_155 NECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 CGVLVVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA MSMEG_0408|M.smegmatis_MC2_155 CGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 EALQRAGIAPGDVDYLEAHGTGTSLGDPIEVQAAGAVLGAGREASRPLLI MSMEG_0408|M.smegmatis_MC2_155 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLI TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 GSVKTNIGHLEAAAGIAGVIKVILALEHGMLPQHLHFRDPSPHIPWDRLA MSMEG_0408|M.smegmatis_MC2_155 GSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWERLP TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 VQVVKEATAWQRNGRPRVAGVSSFGFAGTNAHVILEEAPDGTGRAAVPPA MSMEG_0408|M.smegmatis_MC2_155 IEVVRETVPWQRNGKPRIAGVSSFGFAGTNAHVILEEAP-AVGTPATTEP TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 AVRPPGQRRFHVLPLSARTPAALVQIAGEYRDWLSAHPDTALADLCLTAG MSMEG_0408|M.smegmatis_MC2_155 VEDP---RRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVSHTAG TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 AGRAHFEHRAALVVDSTGSAGELLAALADDRPAPGLLRGVCEDAPKTAWL MSMEG_0408|M.smegmatis_MC2_155 TARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWL TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 FTGQGSQYAGMARELFDTEPVFAETLTRCATVLADVLEKPLLDVIFDTDD MSMEG_0408|M.smegmatis_MC2_155 FTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADE TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 P--ASEATLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSA MSMEG_0408|M.smegmatis_MC2_155 LDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSA TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 ACVAGVLRVEDGARLIAERGRLFGSLPAGGRMVAAFAAAARVEGLTDEFP MSMEG_0408|M.smegmatis_MC2_155 ACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYP TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 SLSVAAYNGANTVLSGPGQELEQAVARLTAEKVRCDWLDTSHAFHSALLD MSMEG_0408|M.smegmatis_MC2_155 SLSVAAYNGANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLD TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 PILDEFESYANQFDFGPPQRILICNRTGSALGRSVKLDGAYWRRHARQPV MSMEG_0408|M.smegmatis_MC2_155 PILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPV TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 EFAKSVHTLADLGCKVLLEIGPQPVLTAAALRAWPDPATAPRAIASLRRN MSMEG_0408|M.smegmatis_MC2_155 EFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPT TH_4458|M.thermoresistible__bu ---------------------------------------------LLSLL Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 TADHRQITEALAEAYIVGHLPDFGAAVGP-ARKLDLPTYPFQHRQYWFSE MSMEG_0408|M.smegmatis_MC2_155 TADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSD TH_4458|M.thermoresistible__bu RQRSERYGDKIAFDYCTGEQEHSRLTYQELDIRARAIAAHLQDQGVAGER Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 QRVPPGSQQTS-------TQTTAVRLLEDGRIAELAELLDGASADQHTLD MSMEG_0408|M.smegmatis_MC2_155 NRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLR TH_4458|M.thermoresistible__bu VLVLCPSGLDFITAMFGCFYVGAVAVPVHPPVHNRLLSRVASIVADVRAT Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 VLTKLAAQHNQQRKSRSIAEDRYEIRWEKSTVPGP--EAEATWLVVGDDD MSMEG_0408|M.smegmatis_MC2_155 VLNKLAARHNQQRSTHVDPDARYEIRWDAIASAAASTGAAADWILVGDDT TH_4458|M.thermoresistible__bu SVLTTAATRADLKEILDGLHDGDPLRWLAVDTIEADDETSWTPTTVDTDS Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 DAVAPLVDALTARGHQHRILVLPASDADEERLEIVLRAAAAEEAPLRIAL MSMEG_0408|M.smegmatis_MC2_155 AAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGE--LYVVH TH_4458|M.thermoresistible__bu VAFVQYTSGSTSTPKG-----------------VVLTHHNLLANLESISR Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 VAALDSGTAPSMRSLLRMQHRVLAGTRRLFRAAAAAELRQPIWLVTRGAQ MSMEG_0408|M.smegmatis_MC2_155 IAAGDGAAAP-MRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQ TH_4458|M.thermoresistible__bu DAGQGDEARVVSWLPLHHDMGLIGGIFGVVHFGGTAYLMPPSSFIQRPMS Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 RVTDADTVFPDQSCLWGFGRAASLEYPQLWGGLADLAQGSAEEWSRLVRV MSMEG_0408|M.smegmatis_MC2_155 RVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLS-GADTEWPRLIAR TH_4458|M.thermoresistible__bu WLEAISWHGANISVGPNFG--------------YQLCVERSTPEERATLD Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 ASAPRDPAVGEDQIALRGSDIYVPRLTRRSGQPAAAALTLRADATYLVTG MSMEG_0408|M.smegmatis_MC2_155 ITSPRD---GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTG TH_4458|M.thermoresistible__bu LSTWVRAYCGAEPVRAATMRRFTEAFAPAGFRADAFHPVYGLAEATLFVS Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 ------------------------------------------------MQ MAV_1763|M.avium_104 GLGSIGLEIAGHLAAQGARHLVLTGRRAPGEAAQRRIDALSQQHGCEVRV MSMEG_0408|M.smegmatis_MC2_155 GLGAIGLEVAGYLASHGAGHVVLTSRREPGDDARRRLDGLREQYACDVRV TH_4458|M.thermoresistible__bu GRPENVLPTVRSLDNAALREHRVVPAAADDANAAAVVGCGPAAYGEEIVI Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 HSSTAAELQRKWLRGGAFEPDRHPALVVFPHAGGGATFYRSWLTNPDFSV MAV_1763|M.avium_104 IAADVADAHHVARLLGAVRAELPPVAGIVHAAGEIGTTPLSDLEDAEIDR MSMEG_0408|M.smegmatis_MC2_155 ITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDR TH_4458|M.thermoresistible__bu VDPATRREFPPDVVGEIWVAGENVAQGYLGKPSESAETFAAHLADSGRGP Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 HVVQYPGREDRISEQLPSSLG----------------------------- MAV_1763|M.avium_104 VFAGKVWGAWHLSEAAADLR--LDFFVSTSSIASVWGGLGQTAYGAANAF MSMEG_0408|M.smegmatis_MC2_155 VFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAF TH_4458|M.thermoresistible__bu FLRTGDYGFLLDGELFVTGRLKDLIIIRGRNYHPNDIEATVQEVHPALMS Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------ALADGVAEALLTVGDRPLYLFGHSMGALVAFEVARRLETADRF MAV_1763|M.avium_104 LDGLAWRLREQGVNGISVNFGPWAAGMADENARARLAQRGIKTLSPADAL MSMEG_0408|M.smegmatis_MC2_155 LDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGVRTLSPAEAL TH_4458|M.thermoresistible__bu GRGAAFAVSPDPSGTEQLVIVQEVDRGRLGEVDTDELIAAIRTAVTSQHD Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 RQLRLCVSSYTAPHLVRSRGLRDMDDEAFVAYGRSATGEVSAATGEASA- MAV_1763|M.avium_104 AGLADVMATAAAQGVVARIDWTRFLPLYQQAGQRSLLAELAREIPDFAP- MSMEG_0408|M.smegmatis_MC2_155 AGMADVVAG-PVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATG TH_4458|M.thermoresistible__bu IGVHTVVLVDPLRIPTTSSGKIRRRTCRQRFLDGELDAFAEWRLATPRPA Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 --------FDVTALRDLVVAGLRADFHLVEQYRAEPKPPVDAPILALWGD MAV_1763|M.avium_104 ---APTPSGKTGLVERLAGAPVQQRRKLMTEFLRNAVAEVTRVDAAEIRE MSMEG_0408|M.smegmatis_MC2_155 AAAPATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRD TH_4458|M.thermoresistible__bu QPVPAADEQADEQAG--AGPGAGPGADEIRAWFVAQLAGELGLSPDDIDT Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 DEAIDPADMDLWADVTRGGYRSA------------TFPGGHFYLAAER-- MAV_1763|M.avium_104 DAGFFDLGMDSLMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLL-- MSMEG_0408|M.smegmatis_MC2_155 EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLL-- TH_4458|M.thermoresistible__bu GQPFAYYGLDSVRAIQLMTALEAWSGIKVAPTLAYDHPTIDLAAEHLAGL Mflv_3390|M.gilvum_PYR-GCK ------------MTSGTRDSTSDSPQDSLPDNAIAVIGMAGRFPGAQSVS Mvan_3123|M.vanbaalenii_PYR-1 ------------MTSGASNNT-----DELPDNAIAVIGMAGRFPGAGSVS Rv2935|M.tuberculosis_H37Rv --------------------------MSIPENAIAVVGMAGRFPGAKDVS Mb2960|M.bovis_AF2122/97 --------------------------MSIPENAIAVVGMAGRFPGAKDVS MLBr_02353|M.leprae_Br4923 --------------------------MITPDNAIAVVGMAGKFPGANDVS MMAR_1772|M.marinum_M -------------------------MSTIPDNAIAVVGMAGKFPGAKDVS MUL_2015|M.ulcerans_Agy99 -------------------------MSTIPDNAIAVVGMAGKFPGAKDVS MAB_2256|M.abscessus_ATCC_1997 ---DAVLETVRQWWAELDGESEASEVHEVRDDDVAVIGIAARVPGAASLD MAV_1763|M.avium_104 ---GDVLDLRGQPDAKPAPPAGTPAPAGRTDEPIAIVAMACRFPGAADPE MSMEG_0408|M.smegmatis_MC2_155 ---VEVLGLGEQTNVRQAS-----TVTARTDDPIAVVAVSCRFPGAPDPE TH_4458|M.thermoresistible__bu THTATSTAADAGVSTGAGRRPEHGPAPDRADEPIAIIGIGCRFPGADGPA :: :*::.:. :.*** . Mflv_3390|M.gilvum_PYR-GCK EFWRNLRGGVESIVDLSESELLAAGVTEQTLANR--SYVRRAALMSGIEE Mvan_3123|M.vanbaalenii_PYR-1 EFWRNLRNGVESIVDLPEDELLANGVTERTLSNR--SYVRRAGLMPGIDE Rv2935|M.tuberculosis_H37Rv AFWSNLRRGKESIVTLSEQELRDAGVSDKTLADP--AYVRRAPLLDGIDE Mb2960|M.bovis_AF2122/97 AFWSNLRRGKESIVTLSEQELRDAGVSDKTLADP--AYVRRAPLLDGIDE MLBr_02353|M.leprae_Br4923 AFWTNLRRGKESIVTLSEQELRDNGVSDKALADP--AYVRRAPLLDGIDE MMAR_1772|M.marinum_M TFWSNLRRGKESIVTLSEEELREAGVSDKTLADP--SYVRRAPLVDGIDE MUL_2015|M.ulcerans_Agy99 TFWSNLRRGKESIVTLSEEELREAGVSDKTLADP--SYVRRAPLVDGIDE MAB_2256|M.abscessus_ATCC_1997 EFWTNLCAGEESLTRFTDEELLSAGVTPEELRDP--RLVRVRPILADVAD MAV_1763|M.avium_104 AFWELLSGGVDAIREVPEDRFDIDEFYDPDPETPGKMYSRFGGYLDQIDE MSMEG_0408|M.smegmatis_MC2_155 SFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRFGGFLDGIDG TH_4458|M.thermoresistible__bu AYWRLLREGRDAITATPPERWDTDSVGDG---------TRWGGFLERIDG :* * * ::: . .. . * : : Mflv_3390|M.gilvum_PYR-GCK FDADFFGFTPQAAKALDPQHRLFLQTVFHAFEDAGYDPKGLEATVGVFGT Mvan_3123|M.vanbaalenii_PYR-1 FDADFFGFTPYAARMLDPQHRLFLQTVFHAMEDAGYDPKGLEATVGVFGT Rv2935|M.tuberculosis_H37Rv FDAGFFGFPPLAAQVLDPQHRLFLQCAWHALEDAGADPARFDGSIGVYGT Mb2960|M.bovis_AF2122/97 FDAGFFGFPPLAAQVLDPQHRLFLQCAWHALEDAGADPARFDGSIGVYGT MLBr_02353|M.leprae_Br4923 FDADFFGLPPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGT MMAR_1772|M.marinum_M FDADFFGFPPLAAQVLDPQHRLFLQCAWHALEDANCDPAKFDGSIGVYGT MUL_2015|M.ulcerans_Agy99 FDADFFGFPPLAAQVLDPQHRLFLQCAWHALEDANCDPAKFDGSIGVYGT MAB_2256|M.abscessus_ATCC_1997 FDTKFFGYAPSEARSIDPQQRLFLECAWEAVESAGYDLQRYDGSVGVFGG MAV_1763|M.avium_104 FDPEFFGISPREAVWIDPQQRLVLETVWEGLERAGYSPAALRGSRSGIFV MSMEG_0408|M.smegmatis_MC2_155 FDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFT TH_4458|M.thermoresistible__bu FDAGFFGISPREAVRIDPQQRLLLEVAWEALEDAGLVPDRLAGSRTGVFT **. *** .* * ::**:**.*: .:...* *. .: Mflv_3390|M.gilvum_PYR-GCK SSTSGYLLHNLMSNYDPMMVIGQGASFDMVSLSLSNDKDHLATRVAHSYD Mvan_3123|M.vanbaalenii_PYR-1 SSSSGYLLHNLMSNFDPMMVIGQGASFEMVNLSLQNDKDHLATRAAHQFD Rv2935|M.tuberculosis_H37Rv SSPSGYLLHNLLSHRDPNAVLAEGLNFDQFSLFLQNDKDFLATRISHAFN Mb2960|M.bovis_AF2122/97 SSPSGYLLHNLLSHRDPNAVLAEGLNFDQFSLFLQNDKDFLATRISHAFN MLBr_02353|M.leprae_Br4923 SSPSGYLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDKDFLATRISHAFN MMAR_1772|M.marinum_M SSPSGYLLHNLLSHRDPNTVLAEGLNFDQFSLFLQNDKDFLATRISHAFN MUL_2015|M.ulcerans_Agy99 SSPSGYLLHNLLSHRDPNTVLAEGLNFDQFSLFLQNDKDFLATRISHAFN MAB_2256|M.abscessus_ATCC_1997 SAGSTYYRAVLSTDYG------NLNGTEYLQTALATENDFLAPRVSYKLN MAV_1763|M.avium_104 GVGANEYSHLLS---------AESVDKIEPHFITGNALNAISGRVAFALG MSMEG_0408|M.smegmatis_MC2_155 GVAANEYAHLLS---------AESIDKIEPHFITGNALNAISGRVAFALG TH_4458|M.thermoresistible__bu GVSTYDYLHLQLS----------HPELIDAYSGTGTASSIAANRLSYVFD . : . . : * :. . Mflv_3390|M.gilvum_PYR-GCK LRGPALSVATACSSSLVAVHLACQSILNGECDIALAGGSSLRIPNRVGYW Mvan_3123|M.vanbaalenii_PYR-1 FRGPALSVATACSSSLVAVHLACQSLLNGECDIALAGGSSLRIPHHVGYW Rv2935|M.tuberculosis_H37Rv LRGPSIAVQTACSSSLVAVHLACLSLLSGECDMALAGGSSLCIPHRVGYF Mb2960|M.bovis_AF2122/97 LRGPSIAVQTACSSSLVAVHLACLSLLSGECDMALAGGSSLCIPHRVGYF MLBr_02353|M.leprae_Br4923 LRGPSIAVQTACSSSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYW MMAR_1772|M.marinum_M LRGPSIAVQTACSSSLVAVHLACLSLLSGECDVALAGGSSLCVPHHVGYF MUL_2015|M.ulcerans_Agy99 LRGPSIAVQTACSSSLVAVHLACLSLLSGECDVALAGGSSLCVPHHVGYF MAB_2256|M.abscessus_ATCC_1997 LRGPSISLGTGCSTSLVAIHLAVQSVLTGESDMALAGGASITFPQTAGYV MAV_1763|M.avium_104 LEGPAVAVDTACSSSLVAVHQACQALHSGDCDLALAGGVNVLLSPVSNIA MSMEG_0408|M.smegmatis_MC2_155 FEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVA TH_4458|M.thermoresistible__bu FRGPSLTLDSACSSSLVAVHQACRSLRDGECDLALAGGVNIMLSAGIGLN :.**:::: :.**::***:* * :: *:.*:***** .: .. Mflv_3390|M.gilvum_PYR-GCK YAQGSMVTPTGQCRPFDVRADGTVFGSGVGVLVLKALEDAVADGDRIHAV Mvan_3123|M.vanbaalenii_PYR-1 YEQGAMVSPTGQCRPFDVRSDGTIFASGVGVVVLKALADAIDDGDHIHAV Rv2935|M.tuberculosis_H37Rv TSPGSMVSAVGHCRPFDVRADGTVFGSGVGLVVLKPLAAAIDAGDRIHAV Mb2960|M.bovis_AF2122/97 TSPGSMVSAVGHCRPFDVRADGTVFGSGVGLVVLKPLAAAIDAGDRIHAV MLBr_02353|M.leprae_Br4923 HSPGSMVSAVGHCRPFDVRADGTVFGSGVALVALKPLQAAIDASDRIHAV MMAR_1772|M.marinum_M TSPGSMVSAVGHCRPFDVRSDGTVFGSGVAMVVLKPLQAAIDAGDRIHAV MUL_2015|M.ulcerans_Agy99 TSPGSMVSAVGHCRPFDVRSDGTVFGSGAAMVVLKPLQAAIDAGDRIHAV MAB_2256|M.abscessus_ATCC_1997 ATESGAISTSGRCRAFDASADGTLVGDGIGIVLLKRASNAVADGDSILGI MAV_1763|M.avium_104 ASRARMLSPVGRCKTFDATADGYVRSEGCGILVLKRMSDAVRDGDRVCAV MSMEG_0408|M.smegmatis_MC2_155 ASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAV TH_4458|M.thermoresistible__bu FTRAGVMATDGRCKTFDARADGWVRGEGAGIVVLKPLREALADEDPIYAV . ::. *:*:.**. :** : ..* .:: ** *: * : .: Mflv_3390|M.gilvum_PYR-GCK IRGSALNNDGATKMTYAAPNALGQAEVIAEAHAIAGVDASTITYVETHGT Mvan_3123|M.vanbaalenii_PYR-1 IRGSALNNDGSTKMTYAAPNALGQAEVIAEAHAIAGVDASSITYVETHGT Rv2935|M.tuberculosis_H37Rv IRGSAINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDSSTVSYVECHGT Mb2960|M.bovis_AF2122/97 IRGSAINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDSSTVSYVECHGT MLBr_02353|M.leprae_Br4923 ILGSAINNDGSMKMGYAAPNPAAQADVIAEAHAVAGIDSSTVSYVETHGT MMAR_1772|M.marinum_M IRGSAINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDASTVSYVECHGT MUL_2015|M.ulcerans_Agy99 IRASAINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDASTVSYVECHGT MAB_2256|M.abscessus_ATCC_1997 IRGTAVNNDGGNKAGFAAPSISGQVEVITEALAVAEVPAQTVDYVETHGT MAV_1763|M.avium_104 IPASAVNQDGAS-SGLTVPNGGAQQRLIATALSRAGLSGDDVDYLEAHGT MSMEG_0408|M.smegmatis_MC2_155 IPASSVNQDGAS-SGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGT TH_4458|M.thermoresistible__bu IRGSAVNQDGRT-NGLMAPSRTAQEVVLTDAYRRAGVSPGVVQYVEAQGI * .:::*:** .*. .* :: : : : : *:* :* Mflv_3390|M.gilvum_PYR-GCK GTPLGDPIEVEGLRQAFELAEDERSAPCYLGSVKSNIGHLETAAGIAGLI Mvan_3123|M.vanbaalenii_PYR-1 GTPLGDPIEIEGLRQAFELSEETRSAPCYLGSVKSNIGHLETAAGIAGLI Rv2935|M.tuberculosis_H37Rv GTPLGDPIEIQGLRAAFEVSQTSRSAPCVLGSVKSNIGHLEVAAGIAGLI Mb2960|M.bovis_AF2122/97 GTPLGDPIEIQGLRAAFEVSQTSRSAPCVLGSVKSNIGHLEVAAGIAGLI MLBr_02353|M.leprae_Br4923 GTPLGDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIGHLEVAAGIAGLI MMAR_1772|M.marinum_M GTPLGDPIEIQGLRTAFEASETTRTGPCVLGSVKSNIGHLEVAAGIAGLI MUL_2015|M.ulcerans_Agy99 GTPLGDPIEIQGLRTAFEASETTRTGPCVLGSVKSNIGHLEVAAGIAGLI MAB_2256|M.abscessus_ATCC_1997 GTPLGDPIEIAALHKAFREAGDTRTQACRLGTLKPNIGHTGPASGVLALI MAV_1763|M.avium_104 GTALGDPIEVQAAGAVYGATRDTDR-PLLIGSVKTNIGHLEAASGVAGLI MSMEG_0408|M.smegmatis_MC2_155 GTPLGDPIEVQAAAAAYGAGRDADR-PLLMGSVKTNIGHTESASGAAGLI TH_4458|M.thermoresistible__bu GTPVGDAIEVGALGTVLAEDRPPDS-PCLIGSVKTNIGHLEAAAGIAGLI **.:**.**: . . . :*::*.**** *:* .** Mflv_3390|M.gilvum_PYR-GCK KAILCLEHKAIPATLHYTSPNPELHLDRGPFRVRAQDGPWESDG--IRRA Mvan_3123|M.vanbaalenii_PYR-1 KAILCLEHKAIPATLHYTSPNPELHLDRGPFRIRSSDGPWESDG--IRRA Rv2935|M.tuberculosis_H37Rv KTILCLKNKALPATLHYTSPNPELRLDQSPFVVQSKYGPWECDG--VRRA Mb2960|M.bovis_AF2122/97 KTILCLKNKALPATLHYTSPNPELRLDQSPFVVQSKYGPWECDG--VRRA MLBr_02353|M.leprae_Br4923 KTILCLKNKAIPATLHYTSPNRELRLDQTPFVVQSNYGPWKWDG--VRRA MMAR_1772|M.marinum_M KTILCLKNRAIPATLHYTSPNPELRLEQSPFVVQNKYGPWEWDG--VLRA MUL_2015|M.ulcerans_Agy99 KTILCLKNRAIPATLHYTSPNPELRLEQSPFVVQNKYGPWEWDG--VLRA MAB_2256|M.abscessus_ATCC_1997 KVLLAFQHRMYPPAANFTAPNPQIEFSKSPFYVGTRLRRWNAPGGKPRRA MAV_1763|M.avium_104 KVVLSLQHEMLPQSLHFETPSPHIPWDSLPLRVVDKAVPWQTNG-RPRRA MSMEG_0408|M.smegmatis_MC2_155 KVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNG-RVRRA TH_4458|M.thermoresistible__bu KVALALRHRMIPPTLNFTEPNPTIEFDKLPVRVAQTLTPWPDDS-GRAVA *. *.:.: * : :: *. : . *. : * . * Mflv_3390|M.gilvum_PYR-GCK GVSSFGVGGTNAHIILEEAP-----------VAPARAQTSSPARPSVLVL Mvan_3123|M.vanbaalenii_PYR-1 GVSSFGVGGTNAHIVLEEAP-----------TAPVPAPRSG---PQVLVL Rv2935|M.tuberculosis_H37Rv GVSSFGVGGTNAHVVLEEAPA----------EASEVSAHAEPAGPQVILL Mb2960|M.bovis_AF2122/97 GVSSFGVGGTNAHVVLEEAPA----------EASEVSAHAEPAGPQVILL MLBr_02353|M.leprae_Br4923 GVSSFGVGGTNVHVVLEEASV----------EASTVAAS---TGPQVILL MMAR_1772|M.marinum_M GVSSFGVGGTNAHVVLEEAP--------------TVPAHDEPAGPQVLLL MUL_2015|M.ulcerans_Agy99 GVSSFGVGGTNAHVVLEEAP--------------TVPAHDEPAGPQVLLL MAB_2256|M.abscessus_ATCC_1997 GVSSYSMGGTNAHAVLQEPP-------------RAELPPKSQEGAHLLVL MAV_1763|M.avium_104 GVSSFGFTGTNAHVLIEEAPQPVTTQDAT---PAAESDARPVD---VLPL MSMEG_0408|M.smegmatis_MC2_155 GVSSFGFTGTNAHVLVEEAPPQLHTADAAPVEPAATAEAGTDDSPQVLAL TH_4458|M.thermoresistible__bu GVSAFGFGGTNAHVVLAEAPQVR---------AAATADDHADGFVEILPL ***::.. ***.* :: *.. :: * Mflv_3390|M.gilvum_PYR-GCK SARTQEALEDSRATLARELGENAEISLPDVAYTLGR-RRKEPIRLAAVVR Mvan_3123|M.vanbaalenii_PYR-1 SARTEETLAQSRAALAAELSEVDEISLPDAAYTLTH-RRKDPVRLAAVVH Rv2935|M.tuberculosis_H37Rv SAQTAAALGESRTALAAALETQDGPRLSDVAYTLAR-RRKHNVTMAAVVH Mb2960|M.bovis_AF2122/97 SAQTAAALGESRTALAAALETQDGPRLSDVAYTLAR-RRKHNVTMAAVVH MLBr_02353|M.leprae_Br4923 SAQTAAALGESREALATVLEKPGAPDLSDVAYTLAG-RRKHNITMAAVVR MMAR_1772|M.marinum_M SAQTAAALTESRTALAEVLERSDSPDLSDVAYTLSR-RRKHNVTMAAVVS MUL_2015|M.ulcerans_Agy99 SAQTAAALTESRTALAEVLGRSDSPDLSDVAYTLSR-RRKHNVTMAAVVS MAB_2256|M.abscessus_ATCC_1997 SARTAPALEAARKNLAHHLARHPEQDLAAVAATLRLGRRAFSHRFAAVCA MAV_1763|M.avium_104 SARSPEALLALAQRYGEWLHAHPDADIGDLCFTVGAGRAHFEHRAALVVD MSMEG_0408|M.smegmatis_MC2_155 SARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVD TH_4458|M.thermoresistible__bu SARSQAALDALAERYESALTG--GVPPADLCHTAGARRAHHDHRLAVVGA **:: :* * . * * * * Mflv_3390|M.gilvum_PYR-GCK DQANAATVLSAAETDGATDNVFIGR--------GHPDWDSSATDRIAFLF Mvan_3123|M.vanbaalenii_PYR-1 DQENAATVLSAAETD----NVFIGR--------AVPDLQDSA-ERVAFLF Rv2935|M.tuberculosis_H37Rv DREHAATVLRAAEHD----NVFVGEAAHDGEHGDRADAAPT-SDRVVFLF Mb2960|M.bovis_AF2122/97 DREHAATVLRAAEHD----NVFVGEAAHDGEHGDRADAAPT-SDRVVFLF MLBr_02353|M.leprae_Br4923 DREHAVTVLRAAEHD----NVFVGESGADTGRSAAASITTLGSDRVVFLF MMAR_1772|M.marinum_M DREEAATALRAADND----SIFVGESVAG-----VADATAAAAERVVFLF MUL_2015|M.ulcerans_Agy99 DREEAATALRAADND----SIFVGESVAG-----VADATAAAAERVVFLF MAB_2256|M.abscessus_ATCC_1997 DRPEALQVLEGTGHAP-----------------FRTGTAADKPRPVVFLF MAV_1763|M.avium_104 SVRSAREALADLADNR--------------TRPGVARGECTDPPTTAWLF MSMEG_0408|M.smegmatis_MC2_155 SVERAREGLAALAEGR--------------TPAGVVRGEHVHRPTTAWLF TH_4458|M.thermoresistible__bu SRAELIGALAAYRRGE------------PHPGVFTGRSQSGHRSGVVFVF . * .::* Mflv_3390|M.gilvum_PYR-GCK PGQGAQHIGMARGLHDNEPVFARYFDECATAFSDEMG-FDLRAEIFDG-- Mvan_3123|M.vanbaalenii_PYR-1 PGQGAQHVGMARGLYDNEPVFKRHFDECATAFSDDMG-YDLRAEIFDG-- Rv2935|M.tuberculosis_H37Rv PGQGAQHVGMAKGLYDTEPVFAQHFDTCAAGFRDETG-IDLHAEVFDG-- Mb2960|M.bovis_AF2122/97 PGQGAQHVGMAKGLYDTEPVFAQHFDTCAAGFRDETG-IDLHAEVFDG-- MLBr_02353|M.leprae_Br4923 PGQGAQHVGMAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNG-- MMAR_1772|M.marinum_M PGQGAQHVGMAKGLYETEPVFAEHFDACAAGFRAEMG-VDLNAEIFNG-- MUL_2015|M.ulcerans_Agy99 PGQGAQHVGMAKGLYETEPVFAEHFDACAAGFRAEMG-VDLNAEIFNG-- MAB_2256|M.abscessus_ATCC_1997 PGQGSQFSGMGEQLYTTSSMYRRHIDECATLFEPLIG-VDLRTMLCAEGD MAV_1763|M.avium_104 TGQGSQYPGMARELFDAEPVFAETVTRCADAVDGLLP-RPLTEVIFATDK MSMEG_0408|M.smegmatis_MC2_155 TGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLP-RPLLDVLFATDR TH_4458|M.thermoresistible__bu SDEGSQWRGMAQRLYAEDQVFRTALAECDRALRRHMEISPLSELLADP-- ..:*:* **.. *. . :: . * . * : Mflv_3390|M.gilvum_PYR-GCK -----VGRNLEHTDRAQPALFTVEYALARLIQSYGVEPAIMAGHSIGEYP Mvan_3123|M.vanbaalenii_PYR-1 -----VGRNLEHTDRAQPALFTVEYALAKLVQSYGVEPAIMAGHSIGEYP Rv2935|M.tuberculosis_H37Rv -----TATDLERIDRSQPALFTVEYALAKLVDTFGVRAGAYIGYSTGEYI Mb2960|M.bovis_AF2122/97 -----TATDLERIDRSQPALFTVEYALAKLVDTFGVRAGAYIGYSTGEYI MLBr_02353|M.leprae_Br4923 -----TAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYSTGEYI MMAR_1772|M.marinum_M -----TATDLERIDRSQPALFTVEYALAKLVDTYGVRAGAYIGYSTGEYI MUL_2015|M.ulcerans_Agy99 -----TGTDLERIDRSQPALFTVEYALAKLVDTYGVRAGAYIGYSTGEYI MAB_2256|M.abscessus_ATCC_1997 EA---TDAALMQTRLTQPALFTVGYALSQLLGAWGVQPVAMLGHSIGELV MAV_1763|M.avium_104 DTGGEAGKTLRNTAFAQPALFAVEMGLARLWQSWGVEPDVVLGHSVGQYA MSMEG_0408|M.smegmatis_MC2_155 ET----ADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYA TH_4458|M.thermoresistible__bu -----SHSRMDEVTIASPALFAVQVALAALWQSWGVEPAAVIGHRMGEVA : . :.****:* .*: * ::.: . *: *: Mflv_3390|M.gilvum_PYR-GCK AATLAGVFDLDTAVKVVATRAKLMHAAPRG-VMIAVPLSPDAVAEYLTP- Mvan_3123|M.vanbaalenii_PYR-1 AATIAGVFDLDTAVKVVSKRAKLMHAAPRG-VMVAVPLSPEAVAEHLTP- Rv2935|M.tuberculosis_H37Rv AATLAGVFDLQTAIKTVSLRARLMHESPPG-AMVAVALGPDDVTQYLPP- Mb2960|M.bovis_AF2122/97 AATLAGVFDLQTAIKTVSLRARLMHESPPG-AMVAVALGPDDVTQYLPP- MLBr_02353|M.leprae_Br4923 AATLAGVFDLETAIKTVSLRARLMHESPPG-AMVAVALGPEDITEYLAEY MMAR_1772|M.marinum_M AATLAGVFDLETAIKTVSLRARLMHESPPG-AMVAVAVGPDEIAQYLGD- MUL_2015|M.ulcerans_Agy99 AATLAGVFDLETAIKTVSLRARLMHESPPG-AMVAVAVGPDDFAQYLGD- MAB_2256|M.abscessus_ATCC_1997 AACAAGVFTIEEAVQLAARRGDLIQQCPSG-AMAAVGGSLEVVSALLPEG MAV_1763|M.avium_104 AACVAGVFSLEDGARLMAERGRLFGGLPDGGRMVAVFADAQYVEELANDC MSMEG_0408|M.smegmatis_MC2_155 AACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF TH_4458|M.thermoresistible__bu AAHVAGVLGLDDAAALLCGRTRLSRLASTG-------------------- ** ***: :: . . * : . * Mflv_3390|M.gilvum_PYR-GCK ---DVDIATINDPGSCVVAGTDEAIRAFQAGLAEKGVAARRVRTAHAFHS Mvan_3123|M.vanbaalenii_PYR-1 ---DVDVATINDPGSCVVAGSEEAIRTFQAALAEKGVAARRVRTSHAFHS Rv2935|M.tuberculosis_H37Rv ---EVELSAVNDPGNCVVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHT Mb2960|M.bovis_AF2122/97 ---EVELSAVNDPGNCVVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHT MLBr_02353|M.leprae_Br4923 SAKGVELSAVNDPGNCVVAGPKDQIRAFSQRLDEVGIPVRRVRATHAFHT MMAR_1772|M.marinum_M ---GVELSAVNDPGNCVVAGPKDEIRAFSQRLNEAGIPVRRVRATHAFHS MUL_2015|M.ulcerans_Agy99 ---GVELSAVNDPGNCVVAGPKDEIRAFSQRLNEAGIPVRRVRATHAFHS MAB_2256|M.abscessus_ATCC_1997 ----VSVAAVNGPEQIVVAGREEGIEALLSTGANVGVRCTRLPVNRGFHS MAV_1763|M.avium_104 P--RVSVAAYNGP-NTVLSGPGADLEQIVARGASDGIRCSWLETSHAFHS MSMEG_0408|M.smegmatis_MC2_155 P--RVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHS TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK RLMDPVVAEFTAFLSGLTLREPQIPLLSNVTGTTMSASEATNPSTWARQI Mvan_3123|M.vanbaalenii_PYR-1 RLMDPVVAEFGAFLSGVTLREPQIPLLSNITGTTMTAAEATNPSTWARQI Rv2935|M.tuberculosis_H37Rv SAMDPMLGQFQEFLSRQQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQI Mb2960|M.bovis_AF2122/97 SAMDPMLGQFQEFLSRQQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQI MLBr_02353|M.leprae_Br4923 SSMEPMLREFSEFLSRQQLRVPNTPLLSNLTGTWMSEQQVTDPENWTRQI MMAR_1772|M.marinum_M SSMEPMLGEFQEFLSRQQLRAPQTPLLSNLTGTWLSEQQVTDPATWARQI MUL_2015|M.ulcerans_Agy99 SSMEPMLGEFQEFLSRQQLRAPQTPLLSNLTGTWLSEQQVTDPATWARQI MAB_2256|M.abscessus_ATCC_1997 ALVDPAVSSFSAAVARMRLQQPQVPFISNVTGTWITGAQATEPEYWGRQL MAV_1763|M.avium_104 ELLDPVLDEFESYAAHLDFAVPTLPLVCNRTGTVLTTETPLDARYWRRHS MSMEG_0408|M.smegmatis_MC2_155 ELLDPVLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPLDAQYWRRHS TH_4458|M.thermoresistible__bu ----AVREGLDGLLANLRPDDPRIPLYSTVTGDAVTG-RGFGAAHWMENL . : : * *: .. ** :: . * .: Mflv_3390|M.gilvum_PYR-GCK RATVRFADELDALLAA-PDRVLVEVGPGGTLTSSAGRHPRWSERHRAVRL Mvan_3123|M.vanbaalenii_PYR-1 RATVRFADELDALLAA-PDRVLVEVGPGGTLTSSAGRHPKWTERHRAVRL Rv2935|M.tuberculosis_H37Rv SSPIRFADELDVVLAA-PSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRL Mb2960|M.bovis_AF2122/97 SSPIRFADELDVVLAA-PSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRL MLBr_02353|M.leprae_Br4923 SSTIRFADELDVVLSQ-SGRVLVEVGPGGSLTGSAMRHPRWSSGHRAVRL MMAR_1772|M.marinum_M SSTVRFADELDVVLSQ-PNRILVEIGPGGSLTGSAIRHPKWSDGHRSVRL MUL_2015|M.ulcerans_Agy99 SSTVRFADELDVVLSQ-PNRILVEIGPGGSLTGSAIRHPKWSDGHRSVRL MAB_2256|M.abscessus_ATCC_1997 RETVQFARGLTTLCAEYPDALLVEVGPGHTLRGIVAAN---TPASEVVSM MAV_1763|M.avium_104 RQPVQFAESVRTVAAL-GCTVLMEIGPQPVLTG--AAVQVWPEHLAAPRA MSMEG_0408|M.smegmatis_MC2_155 RQPVQFAESVRTVAAL-GCSVLMEIGPQPVLTG--AAVQVWPEHMAAPRA TH_4458|M.thermoresistible__bu HSPVRFSAAVRRLLGR-GHDAFLEISAHPMLLS--AVQEDAADLGRSCTT .::*: : : . ::*:.. * . . Mflv_3390|M.gilvum_PYR-GCK MRHQAQNRSDDDTFHLALGQLWAADVDVDWTQGDQDAADARTLVTLPGYP Mvan_3123|M.vanbaalenii_PYR-1 MRHQAQNRNDHDTFLLALGQLWAADVEVDFNQG---AEEDRTLITLPGYP Rv2935|M.tuberculosis_H37Rv MRHPLQDVDDRDTFLRALGELWSAGVEVDWTPR---RPAVPHLVSLPGYP Mb2960|M.bovis_AF2122/97 MRHPLQDVDDRDTFLRALGELWSAGVEVDWTPR---RPAVPHLVSLPGYP MLBr_02353|M.leprae_Br4923 MRHPLQNVDDHDTFLRALGELWSAGIEVDWAPQ---RSVMPHLVSLPGYP MMAR_1772|M.marinum_M MRHPIQNLDDRETFLRALGELWSAGVDVDWTPR---RAASPRIVSLPGYP MUL_2015|M.ulcerans_Agy99 MRHPIQNLDDRETFLRALGELWSAGVDVDWTPR---RAASPRIVSLPGYP MAB_2256|M.abscessus_ATCC_1997 LGDRTG--DSATVALAAAGRLWAGGAELAWQHFG----ASRPRVPLPTYP MAV_1763|M.avium_104 IVSLRKGVGDRRQIAEGLAAAYVSGHRPEFAALHR---RPRRKLELPTYP MSMEG_0408|M.smegmatis_MC2_155 VASLRKGVADRRQIADALASAYVGGHRPDFAAVHR---QPRRPVELPTYP TH_4458|M.thermoresistible__bu LVSMRRGECGRDVLMTSLAALYASGHAVDWARVHP---HGSHCTAAPTYP : . . . : .. : * ** Mflv_3390|M.gilvum_PYR-GCK FARQRHWVEYN----ASSAWVANGSGAAGVSATGAQAGSAAGGAGGGSSV Mvan_3123|M.vanbaalenii_PYR-1 FAKQRHWVEHN----ANAAWLAGGAGADGTAAAAGSAGVAPVAAGGTSTV Rv2935|M.tuberculosis_H37Rv FARQRHWVEPNHTVWAQAPGANNGSPAGTADGSTA--ATVDAARNGESQT Mb2960|M.bovis_AF2122/97 FARQRHWVEPNHTVWAQAPGANNGSPAGTADGSTA--ATVDAARNGESQT MLBr_02353|M.leprae_Br4923 FARQRHWVEPRYTIWAQIPGASSGSPVDSSVDS----ATVEGVRGGESQT MMAR_1772|M.marinum_M FARQRHWVEPKHMAWAQIPTASNGSSVGAKLGSGADSGIRGGAQTGESQT MUL_2015|M.ulcerans_Agy99 FARQRHWVEPKHMAWAQIPTASNGSSVGAKLGSGADSGIRGGAQTGESQT MAB_2256|M.abscessus_ATCC_1997 FERERLWMSPP--------RSVLDKPVQAPIAPAVQVPLVTASTQTDVPD MAV_1763|M.avium_104 FQRRRFWPKASGIAGIDGQGAAASGLLGSAKELASGDSVYTSRLSVKSQP MSMEG_0408|M.smegmatis_MC2_155 FQRRRFWPKASSIA-VDG-GTAASGILGSGKDLASGDTIYTSRLSVKSQP TH_4458|M.thermoresistible__bu WQRQRFWLDIDR------------CDTGDGAGTGGTAERTVVPAPLPAPS : :.* * . Mflv_3390|M.gilvum_PYR-GCK EASLQRIWAQCLGVNEIDRHANFFEIG----------------------- Mvan_3123|M.vanbaalenii_PYR-1 EAKLARIWSQCLGLSDIDRNANFFEIG----------------------- Rv2935|M.tuberculosis_H37Rv EVTLQRIWSQCLGVSSVDRNANFFDLG----------------------- Mb2960|M.bovis_AF2122/97 EVTLQRIWSQCLGVSSVDRNANFFDLG----------------------- MLBr_02353|M.leprae_Br4923 EATLQRIWSQCLGVSSVDRNANFFDLG----------------------- MMAR_1772|M.marinum_M EDVLQRIWSQCLGVGSVDRNANFFDMG----------------------- MUL_2015|M.ulcerans_Agy99 EDVLQRIWSQCLGVGSVDRNANFFDMG----------------------- MAB_2256|M.abscessus_ATCC_1997 AAVVEQIWCEALGVPSVESDDNFFDLG----------------------- MAV_1763|M.avium_104 WLADHVIYGTVVVPGATYAAMALAAVGPPARVQNVYFYEPIILPDKASRE MSMEG_0408|M.smegmatis_MC2_155 WLADHVIYGTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASRE TH_4458|M.thermoresistible__bu ASAAPTVDEVLLCADQRERRE----------------------------- : : Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 VQLSLHPLQEG-GWSFRVDSRPYGVPDAEWSLNADGTV-VAGIEDEPAAD MSMEG_0408|M.smegmatis_MC2_155 VQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAAD TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 P-ADHIDAVIERLDRNRPQLLFDSFAESELEWGTTWSTSLKSLWMGDGEA MSMEG_0408|M.smegmatis_MC2_155 EQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEA TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -GDSLVAISVAMTAGHAGLDLTPQDLYENQTVASLAKVLTARYAEGGLAR Mvan_3123|M.vanbaalenii_PYR-1 -GDSLIAISVAMTAGHEGLDLTPQDLYENQTVAALAKVLTARYAEGGLAR Rv2935|M.tuberculosis_H37Rv -GDSLMAISIAMAAANEGLTITPQDLYEYPTLASLTAAVDASFASSGLAK Mb2960|M.bovis_AF2122/97 -GDSLMAISIAMAAANEGLTITPQDLYEYPTLASLTAAVDASFASSGLAK MLBr_02353|M.leprae_Br4923 -GDSLMAISISMAAANEGMTITPQDMYEHPTLASLTAAVDASFASSGLAK MMAR_1772|M.marinum_M -GDSLMAISIAMSAANEGLTITPQDLYEHPTLASLTAAIDASFASSGLAK MUL_2015|M.ulcerans_Agy99 -GDSLMAISIAMSAANEGLTITPQDLYEHPTLASLTAAIDASFASSGLAK MAB_2256|M.abscessus_ATCC_1997 -GDSLIAARVVTAIGER-----------CHIKVSVAELWDQGATLADLAE MAV_1763|M.avium_104 VGDVTVGDELAEHLGTEPMHPVLLDLCTGVVFPAFPALLAAEQGFNDLLL MSMEG_0408|M.smegmatis_MC2_155 VGDILVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFL TH_4458|M.thermoresistible__bu LLESYLRDRVAAELGVLPPLLDVAAPLSTLGIDSLTAAELRARVERDLGI : : : . :.. .* Mflv_3390|M.gilvum_PYR-GCK QS---------------------VDDSTSPPVPPNVAYFLEHGLRDVGRW Mvan_3123|M.vanbaalenii_PYR-1 QT---------------------LDDAVNPPVPPNVAYFLEHGLRDIGRW Rv2935|M.tuberculosis_H37Rv P----------------------PEAQANPAVPPNVTYFLDRGLRDTGRC Mb2960|M.bovis_AF2122/97 P----------------------PEAQANPAVPPNVTYFLDRGLRDTGRC MLBr_02353|M.leprae_Br4923 P----------------------PEAAAHPAVPPNIAYFLERGLCDTGRW MMAR_1772|M.marinum_M P----------------------PEADANPAVPPNIAYFLDRGLRDTGRW MUL_2015|M.ulcerans_Agy99 P----------------------PEADANPAVPPNIAYFLDRGLRDTGRW MAB_2256|M.abscessus_ATCC_1997 LV---------------------ERRAINSKVGEQLK------------- MAV_1763|M.avium_104 PLRYGQVSLREKMPRRFYCRGKWRPSALDSETQVFDIDFIDRDGRHLGGI MSMEG_0408|M.smegmatis_MC2_155 PLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGI TH_4458|M.thermoresistible__bu VIP--------------------VAQLLNGPSVSDLAEWISTTMVGFG-- Mflv_3390|M.gilvum_PYR-GCK RIPVILGLRSDVGEDDVR-------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 RIPVILGLRSDVGEDDVR-------------------------------- Rv2935|M.tuberculosis_H37Rv RVPLILRLDPKIGLPDIR-------------------------------- Mb2960|M.bovis_AF2122/97 RVPLILRLDPKIGLPDIR-------------------------------- MLBr_02353|M.leprae_Br4923 RVPLILRLDPKIGSDDIR-------------------------------- MMAR_1772|M.marinum_M RVPLILRLDPQVGPEDIR-------------------------------- MUL_2015|M.ulcerans_Agy99 RVPLILRLDPQVGPEDIR-------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 REFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPQPSNDGVANPSGTWL MSMEG_0408|M.smegmatis_MC2_155 REFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSAD---DAVGTWL TH_4458|M.thermoresistible__bu --------------S----------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 IAGFDELGAQLPGCIPFDRNTDPESFGQLLARAEDRGGPVTGIVWRATQS MSMEG_0408|M.smegmatis_MC2_155 IAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATP TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 GGRES--SAESVARLETEIAGLLTAVHALQNADGSAVKLPGGLWIVTERG MSMEG_0408|M.smegmatis_MC2_155 GRKESGSASAESARLEAEITNLLSAVHAAQ---GPSVKLPGGLWIVTEHG TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -----------------AVLTAVTDAHDVLRVRLVERSG----------- Mvan_3123|M.vanbaalenii_PYR-1 -----------------AVLTAVTEVHDALRVHLVERAG----------- Rv2935|M.tuberculosis_H37Rv -----------------AVLTAVVNHHDALRLHLVGNDG----------- Mb2960|M.bovis_AF2122/97 -----------------AVLTAVVNHHDALRLHLVGNDG----------- MLBr_02353|M.leprae_Br4923 -----------------AVLTAVVNHHDVLRLSLVDNDG----------- MMAR_1772|M.marinum_M -----------------AVLSAVTNHHDALRLRLVENGG----------- MUL_2015|M.ulcerans_Agy99 -----------------AVLSAVTNHHDALRLRLVENGG----------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 VATESGEPVDPVQAALWGLGRTIVNEEPALRCRLVDSDGSEQAVRSLAGL MSMEG_0408|M.smegmatis_MC2_155 VACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAAL TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 LGAP-LDEPELAVRQGKLLASRLLPWARSGHLAVPRGTDYVLAPTERGAI MSMEG_0408|M.smegmatis_MC2_155 LAAPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAI TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 DNLRLIEQEAPPPAEGCVQVRVEAGGLNFREVLNVLGLYPGDPGPLGGDF MSMEG_0408|M.smegmatis_MC2_155 DNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDF TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK ----------------------------------IWDQIIAEPGEFTELA Mvan_3123|M.vanbaalenii_PYR-1 ----------------------------------TWDQHIAEPGEFTELV Rv2935|M.tuberculosis_H37Rv ----------------------------------IWEQHIAAPAEFTGLS Mb2960|M.bovis_AF2122/97 ----------------------------------IWEQHIAAPAEFTGLS MLBr_02353|M.leprae_Br4923 ----------------------------------MWEQHIAATGEFTRLL MMAR_1772|M.marinum_M ----------------------------------VWEQHIAAPADFTELA MUL_2015|M.ulcerans_Agy99 ----------------------------------VWEQHIAAPADFTELA MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 AGTVTQLGSGVTGLEVGTRVYGFMQGAFASRFNVPVQLLAPIPDGVSAVD MSMEG_0408|M.smegmatis_MC2_155 AGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVE TH_4458|M.thermoresistible__bu --------------------------------------TTPEPESAGVPG Mflv_3390|M.gilvum_PYR-GCK SRELPSGVAAGSPQEREAVLAFLDEQVREH-QVVVPLTATLIRSGSGGPS Mvan_3123|M.vanbaalenii_PYR-1 ARQLPEGLAAGSPQEREAVLGFLDEQVREH-QVVVPLAATFIRGVTGGPS Rv2935|M.tuberculosis_H37Rv NRSVPNGVAAGSPEERAAVLGILAELLEDQTDPNAPLAAVHIAAAHGGPH Mb2960|M.bovis_AF2122/97 NRSVPDGVAAGSPEERAAVLGILAELLEDQTDPNAPLAAVHIAAAHGGPH MLBr_02353|M.leprae_Br4923 TQTLPDGVAAGSAEERAVVSSILAELIASQSDLNEPLTAVQITTAHGGPH MMAR_1772|M.marinum_M TRQLPGDLAAGEADEHGAVSNIVAELIAEQGDSNAPLIAVHVTAPNGGAQ MUL_2015|M.ulcerans_Agy99 TRQLPDDLAADEADEHSAVSNIVAELIAEQGDSNAPLIAVHVTAPNGGAQ MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 AATIPAAALTARLAFDWAQLKPGDRVLIHAASGGVGLAAIQLAQRHGATV MSMEG_0408|M.smegmatis_MC2_155 AATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEV TH_4458|M.thermoresistible__bu RSRPPDGAVASGSGDGGRWIELLNQMPEVSDDTVDELLRQLLAAGENHDD Mflv_3390|M.gilvum_PYR-GCK YLALSLHGIAGDVSG----DSASRDVLLTDLFTAFNQRMAGEEIVLAPVT Mvan_3123|M.vanbaalenii_PYR-1 YLALSLHGIAG--------DDVSRDVLLTDVFTAFSQRMAGEEIVLAPVP Rv2935|M.tuberculosis_H37Rv YLCLAIHAMVT--------DDSSRQILATDIVTAFGQRLAGEEITLEPVS Mb2960|M.bovis_AF2122/97 YLCLAIHAMVT--------DDSSRQILATDIVTAFGQRLAGEEITLEPVS MLBr_02353|M.leprae_Br4923 YLGLAVHQMVI--------DDASRQILGTDIITAFGQRLAGEEITLEPVT MMAR_1772|M.marinum_M YLGLALHEMVA--------DDASRQLLGADIITAFAQRLGDQEIKLDPVT MUL_2015|M.ulcerans_Agy99 YLGLALHETVA--------DDASRQLLGADIITAFAQRLDDQEIKLDPVT MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 FATASTYKRATLRKLGVEYVYDSRSTDFADQILADTDGAGVDVVLNSLTN MSMEG_0408|M.smegmatis_MC2_155 FATASTFKRSTLRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTS TH_4458|M.thermoresistible__bu TQLH---------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK ASWREWSQRCAGLAGHPAVLDSRDYWLQTAHRST---------------- Mvan_3123|M.vanbaalenii_PYR-1 ASWREWSQRCAGLASHPAVLDSRDYWLQTAGAST---------------- Rv2935|M.tuberculosis_H37Rv TGWREWSLRCAALATHPAALDTRSYWIENSTKAT---------------- Mb2960|M.bovis_AF2122/97 TGWREWSLRCAALATHPAALDTRSYWIENSTKAT---------------- MLBr_02353|M.leprae_Br4923 TGWREWSLRCAALATHPAALDTRSFWIENANKVN---------------- MMAR_1772|M.marinum_M TGWRDWSVRCAALATHPAALDTRSYWIEQSTKAN---------------- MUL_2015|M.ulcerans_Agy99 TGWRDWSVRCAALATHPAALDTRSYWIEQSTKAN---------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 EGFIEATVRATAQHGRFVEIAKRDIWTREQMAAARPDIAYEIVALDWACV MSMEG_0408|M.smegmatis_MC2_155 AGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMF TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK --------LRVAGG----EPADRPGAADLERLSTMLSAAETGEFDDARRR Mvan_3123|M.vanbaalenii_PYR-1 --------LRIAGP----EHSERPGVDDVTRLSTALSAAETGEIDDARRR Rv2935|M.tuberculosis_H37Rv --------LWLADALPNAHTAHPPRADELTKLSSTLSVEQTSELDDGRRR Mb2960|M.bovis_AF2122/97 --------LWLADALPNAHTAHPPRADELTKLSSTLSVEQTSELDDGRRR MLBr_02353|M.leprae_Br4923 --------LWLADVSLNTDVIQPPGADDLIRMPCTLSVEQTSELDDARRR MMAR_1772|M.marinum_M --------LWLTDG----DAAQPPSATDLTKLPSVLNAEQTSELDDARRR MUL_2015|M.ulcerans_Agy99 --------LWLTDG----DAAQPPSATDLTKLPSVLNAEQTSELDDARRR MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 EQPEHIHALLTEVSDGLASGEWRPLPAEIYPLAEAKTAFRRMQQARHIGK MSMEG_0408|M.smegmatis_MC2_155 TEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGK TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK LRLSAEEILLAALGRAVAVTVGEGAVAVDLGGRGRSVLK----------P Mvan_3123|M.vanbaalenii_PYR-1 LRLPVEEILLAALGRAVAATVGEGAVSVDLGGRGRSVLK----------P Rv2935|M.tuberculosis_H37Rv FRRSIQTILLAALGRTIAQTVGEGVVAVELEGEGRSVLR----------P Mb2960|M.bovis_AF2122/97 FRRSIQTILLAALGRTIAQTVGEGVVAVELEGEGRSVLR----------P MLBr_02353|M.leprae_Br4923 FRRSIQAIVLAALGRTIAQTVGDGVVAVELEGEGRSVLR----------P MMAR_1772|M.marinum_M FRRSIQTILLAALGRTIAQTVGDGVVAVELDGEGRSVLR----------P MUL_2015|M.ulcerans_Agy99 FRRSIQTILLAALGRTIAQTVGDGVVAVELDGEGRSVLR----------P MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 IVLQMPKPLQPRGDRSYLITGGLGAIGLHLAAYLAQLGAGEIVLTSRRAP MSMEG_0408|M.smegmatis_MC2_155 IVLQVPKPLQPQQDRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDP TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK DVDLARTVGSFAALHPVVLT-ASGQ--TASAALAEVRQTLDAVPHYGIGY Mvan_3123|M.vanbaalenii_PYR-1 DVDLQRTVGWFTTIHPVVLT-AARQG-SATQALGDVRETLKAVPHYGIGY Rv2935|M.tuberculosis_H37Rv DVDLRRTVGWFTTYYPVPLACATGLG--ALAQLDAVHNTLKSVPHYGIGY Mb2960|M.bovis_AF2122/97 DVDLRRTVGWFTTYYPVPLACATGLG--ALAQLDAVHNTLKSVPHYGIGY MLBr_02353|M.leprae_Br4923 DVDVRRTIGWFTNYYPIPLVCVKGQG--ALAQLDAVHNTLKSIPHYGIGY MMAR_1772|M.marinum_M DVDVRRTVGRFTTYYPVALTCATGQGAAALKGLDAVHDTLKSVPHYGIGY MUL_2015|M.ulcerans_Agy99 DVDVRRTVGRFTTYYPVALTCATGQGAAALKGLDAVHDTLKSVPHYGIGY MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 DAAAWRAIDDITERYRCRVHTFAADVGDAAQVEQLLARIRAELPPLAGVA MSMEG_0408|M.smegmatis_MC2_155 DESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIA TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK GLLRYLYAPTARLLGDGRPADILFSHVGTIPDAPADQPDDAPVRFDPDTA Mvan_3123|M.vanbaalenii_PYR-1 GLLRYLYAPTARVLGASRPADILFSHIGTIPEVPAEQPDDAPVRFDADTA Rv2935|M.tuberculosis_H37Rv GLLRYVYAPTGRVLGAQRTPDIHFRYAGVIPELPSG---DAPVQFDSDMT Mb2960|M.bovis_AF2122/97 GLLRYVYAPTGRVLGAQRTPDIHFRYAGVIPELPSG---DAPVQFDSDMT MLBr_02353|M.leprae_Br4923 GLLRYMYAPTGRVFSAQRTPDIHFRYVGVVPEPPSV---DATVQFDSDMT MMAR_1772|M.marinum_M GLLRYLYAPTGRVLGAQRTPDIHFRYAGTIPELPPV---DAPVQFDSDLA MUL_2015|M.ulcerans_Agy99 GLLRYLYAPTGRVLGAQRTPDIHFRYAGTIPELPPV---DAPVQFDSDLA MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 HLAGVLDDALLSQQSPERFRVALAPKAFGASYLDHATRTDDLDFFIVSSS MSMEG_0408|M.smegmatis_MC2_155 HLAGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSS TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK MPIRDALPGLGHALEVRIYRT------------GGELHLDWWYDIRRLGP Mvan_3123|M.vanbaalenii_PYR-1 MPIRDALPGLGHAVELRVYRA------------AGVLHLDWWYDNRRLGP Rv2935|M.tuberculosis_H37Rv LPVREPIPGMGHAIELRVYRF------------GGSLHLDWWYDTRRIPA Mb2960|M.bovis_AF2122/97 LPVREPIPGMGHAIELRVYRF------------GGSLHLDWWYDTRRIPA MLBr_02353|M.leprae_Br4923 IPVQEPVPGMGHAIELRTYRF------------GGSLHLDWWYDIRRIPQ MMAR_1772|M.marinum_M MPVREPLPGLGHAVEIRAYRS------------GSSLHVDWWYDTRRITA MUL_2015|M.ulcerans_Agy99 MPVREPLPGLGHAVEIRAYRS------------GSSLHVDWWYDTRRITA MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 VSSLLGSPGQANYSTANAWLDGLVAARQARGLPATGVNLGPWAQGGMASS MSMEG_0408|M.smegmatis_MC2_155 VSSLFGSPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASS TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK TDVESFSRQYSAAVLDISREALAEEDTDAAGDELA-------LVDLS--- Mvan_3123|M.vanbaalenii_PYR-1 TDVESFARQYSEALLDVTRDALAEEDTDAAGDELA-------LVDLS--- Rv2935|M.tuberculosis_H37Rv ATAEALERTFPLALSALIQEAIAAEHTEHDDSEIVGEPEAGALVDLSSMD Mb2960|M.bovis_AF2122/97 ATAEALERTFPLALSALIQEAIAAEHTEHDDSEIVGEPEAGALVDLSSMD MLBr_02353|M.leprae_Br4923 VTAEALAQSFPVTLSKLIQEGIATQKDAHDESEMAGAPQAGVLVDLSTLD MMAR_1772|M.marinum_M ETATALARSFPTALSELIQESIAAEQEERDEDEKVGVIEAGALVDLSSLD MUL_2015|M.ulcerans_Agy99 ETATALARSFPTALSELIQESIAAEQEERDEDEKVGVIEAGALVDLPSLD MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 EAARANIGAQGLIPLEPTAALAALAEVVANGTGQATVIKANWQRAAKLLG MSMEG_0408|M.smegmatis_MC2_155 EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLG TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv AG------------------------------------------------ Mb2960|M.bovis_AF2122/97 AG------------------------------------------------ MLBr_02353|M.leprae_Br4923 AG------------------------------------------------ MMAR_1772|M.marinum_M AG------------------------------------------------ MUL_2015|M.ulcerans_Agy99 AG------------------------------------------------ MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 GARPPILDLVLPSAVGEASGDSELLKQLQEIPVAQRAAFITEFLQREVQG MSMEG_0408|M.smegmatis_MC2_155 SARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQN TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 FLRLAQPPAATSRFLDLGTDSLMAVELRNRLHSQFGGAFTINATAVFDYP MSMEG_0408|M.smegmatis_MC2_155 FLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYP TH_4458|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 TIGGLAEYLAGQLPDAESEPGAAVAANPNPGSETGTGEAEPEREAAPEPS MSMEG_0408|M.smegmatis_MC2_155 TIGGLAEYLVGQLPDAEAPETA---------------------------- TH_4458|M.thermoresistible__bu --------------------------------------------------