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M. abscessus ATCC 19977 MAB_2256 (-)

annotation: polyketide synthase
coordinates: 2288717 - 2292490
length: 1257

MQHSSTAAELQRKWLRGGAFEPDRHPALVVFPHAGGGATFYRSWLTNPDFSVHVVQYPGREDRISEQLPS
SLGALADGVAEALLTVGDRPLYLFGHSMGALVAFEVARRLETADRFRQLRLCVSSYTAPHLVRSRGLRDM
DDEAFVAYGRSATGEVSAATGEASAFDVTALRDLVVAGLRADFHLVEQYRAEPKPPVDAPILALWGDDEA
IDPADMDLWADVTRGGYRSATFPGGHFYLAAERDAVLETVRQWWAELDGESEASEVHEVRDDDVAVIGIA
ARVPGAASLDEFWTNLCAGEESLTRFTDEELLSAGVTPEELRDPRLVRVRPILADVADFDTKFFGYAPSE
ARSIDPQQRLFLECAWEAVESAGYDLQRYDGSVGVFGGSAGSTYYRAVLSTDYGNLNGTEYLQTALATEN
DFLAPRVSYKLNLRGPSISLGTGCSTSLVAIHLAVQSVLTGESDMALAGGASITFPQTAGYVATESGAIS
TSGRCRAFDASADGTLVGDGIGIVLLKRASNAVADGDSILGIIRGTAVNNDGGNKAGFAAPSISGQVEVI
TEALAVAEVPAQTVDYVETHGTGTPLGDPIEIAALHKAFREAGDTRTQACRLGTLKPNIGHTGPASGVLA
LIKVLLAFQHRMYPPAANFTAPNPQIEFSKSPFYVGTRLRRWNAPGGKPRRAGVSSYSMGGTNAHAVLQE
PPRAELPPKSQEGAHLLVLSARTAPALEAARKNLAHHLARHPEQDLAAVAATLRLGRRAFSHRFAAVCAD
RPEALQVLEGTGHAPFRTGTAADKPRPVVFLFPGQGSQFSGMGEQLYTTSSMYRRHIDECATLFEPLIGV
DLRTMLCAEGDEATDAALMQTRLTQPALFTVGYALSQLLGAWGVQPVAMLGHSIGELVAACAAGVFTIEE
AVQLAARRGDLIQQCPSGAMAAVGGSLEVVSALLPEGVSVAAVNGPEQIVVAGREEGIEALLSTGANVGV
RCTRLPVNRGFHSALVDPAVSSFSAAVARMRLQQPQVPFISNVTGTWITGAQATEPEYWGRQLRETVQFA
RGLTTLCAEYPDALLVEVGPGHTLRGIVAANTPASEVVSMLGDRTGDSATVALAAAGRLWAGGAELAWQH
FGASRPRVPLPTYPFERERLWMSPPRSVLDKPVQAPIAPAVQVPLVTASTQTDVPDAAVVEQIWCEALGV
PSVESDDNFFDLGGDSLIAARVVTAIGERCHIKVSVAELWDQGATLADLAELVERRAINSKVGEQLK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2256--100% (1257)polyketide synthase
M. abscessus ATCC 19977MAB_2257-0.042.20% (929) polyketide synthase
M. abscessus ATCC 19977MAB_0939-e-14135.07% (904) polyketide synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2960ppsE0.040.33% (1019) phenolpthiocerol synthesis type-I polyketide synthase PPSE
M. gilvum PYR-GCKMflv_3390-0.040.98% (1020) beta-ketoacyl synthase
M. tuberculosis H37RvRv2935ppsE0.040.33% (1019) phenolpthiocerol synthesis type-I polyketide synthase PPSE
M. leprae Br4923MLBr_02353-0.039.33% (1012) polyketide synthase
M. marinum MMMAR_1772ppsE0.040.30% (1010) phenolpthiocerol synthesis type-I polyketide synthase PpsE
M. avium 104MAV_3107-1e-14634.87% (1001) polyketide synthase
M. smegmatis MC2 155MSMEG_0408-1e-13935.12% (914) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4458-1e-11633.00% (1015) PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide
M. ulcerans Agy99MUL_2015ppsE0.040.20% (1010) phenolpthiocerol synthesis type-I polyketide synthase PpsE
M. vanbaalenii PYR-1Mvan_3123-0.040.63% (1019) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDR
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      WDIEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQH
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      RILMETAWRAVEHSGIAPTSLANSNTGVFVGLATHDYLGMASDELTYPEI
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      NECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      CGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLI
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      GSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWERLP
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      IEVVRETVPWQRNGKPRIAGVSSFGFAGTNAHVILEEAPAVGTPATTEPV
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      EDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVSHTAGTARA
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      HLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQ
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      GSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGD
TH_4458|M.thermoresistible__bu      ------------------------------------------------LL
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      TESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVA
TH_4458|M.thermoresistible__bu      SLLRQRSERYGDKIAFDYCTGEQEHSRLTYQELDIRARAIAAHLQDQGVA
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      GVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSV
TH_4458|M.thermoresistible__bu      GERVLVLCPSGLDFITAMFGCFYVG------------AVAVPVHPPVHNR
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      AAYNGANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILD
TH_4458|M.thermoresistible__bu      LLSRVASIVADVRATSVLTTAATRADLKEILDGLHDGDPLRWLAVDTIEA
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      DFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAK
TH_4458|M.thermoresistible__bu      DDETSWTPTTVDTDSVAFVQYTSGSTSTPKG-------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      SVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTADH
TH_4458|M.thermoresistible__bu      -------------------------------VVLTHHNLLANLESISRDA
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      RQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAI
TH_4458|M.thermoresistible__bu      GQGDEARVVSWLPLHHDMG-------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      DRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNK
TH_4458|M.thermoresistible__bu      ----LIGGIFGVVHFGGTAYLMPPSSFIQRPMSWLEAISWHGANISVGPN
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      LAARHNQQRSTHVDPDARYEIRWDAIASAAASTGAAADWILVGDDTAAVL
TH_4458|M.thermoresistible__bu      FGYQLCVERSTPEERATLDLSTWVRAYCGAEPVRAATMRRFTEAFAPAGF
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      EFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDG
TH_4458|M.thermoresistible__bu      RADAFHPVYGLAEATLFVSGRPENVLPTVRSLDNAALREHRVVPAAADDA
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      AAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDT
TH_4458|M.thermoresistible__bu      NAAAVVG---------------------------------CGPAAYGEEI
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      VVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRDGE
TH_4458|M.thermoresistible__bu      VIVDPATRREFP------------------------PDVVGEIWVAGENV
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      ----------------------------------------MQHSSTAAEL
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      DQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAG
TH_4458|M.thermoresistible__bu      AQGYLGKPSESAETFAAHLADSGRGPFLRTGDYGFLLDG-----------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      QRKWLRGGAFEPDRHPALVVFPHAGGGATFYRS-----------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      YLASHGAGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAHDV
TH_4458|M.thermoresistible__bu      --------------------------ELFVTGRLKDLIIIRGRNYHPNDI
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      ----------------------------WLTNPDFSVHVVQYPGREDRIS
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      ARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWH
TH_4458|M.thermoresistible__bu      EATVQEVHPALMSGRGAAFAVSPDPSGTEQLVIVQEVDRGRLGEVDTDEL
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      EQLPSSLGALADGVAEALLTVGDRPLYLFGHSMGALVAFEVARRLETADR
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      LSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRER
TH_4458|M.thermoresistible__bu      IAAIRTAVTSQHDIGVHTVVLVDPLR------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      FRQLRLCVSSYTAPHLVRSRGL----------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      GVTAVSVNFGPWAAGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPV
TH_4458|M.thermoresistible__bu      ----------------IPTTSSGKIRRRTCRQRFLDGELDAFAEWRLATP
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      QGVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGAAAPATVPGKPP
TH_4458|M.thermoresistible__bu      R-------------------------------------PAQPVPAADEQA
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      -----------------------------------RDMDDEAFVAYGRSA
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      LVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSL
TH_4458|M.thermoresistible__bu      DEQAGAGPGAGPGADEIRAWFVAQLAGELGLSPDDIDTGQPFAYYGLDSV
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      TGEVSAATGEASAFDVTALRDLVVAGLRADFHLVEQYRAEPKPPVDAPIL
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      MAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQ
TH_4458|M.thermoresistible__bu      RAIQLMTALEAWSGIKVAPTLAYDHPTIDLAAEHLAGLTHTATSTAADAG
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      ALWGDDEAIDPADMDLWADVTRGGYRSATFPGGHFYLAAERDAVLETVRQ
                                                                                      

MAV_3107|M.avium_104                ----------------MPPTDVAIIGMACRFPGAPDPGSFWRLLRD----
MSMEG_0408|M.smegmatis_MC2_155      AST----------VTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDA
TH_4458|M.thermoresistible__bu      VSTGAGRRPEHGPAPDRADEPIAIIGIGCRFPGADGPAAYWRLLREGRDA
Mb2960|M.bovis_AF2122/97            --------------MSIPENAIAVVGMAGRFPGAKDVSAFWSNLRRGKES
Rv2935|M.tuberculosis_H37Rv         --------------MSIPENAIAVVGMAGRFPGAKDVSAFWSNLRRGKES
MLBr_02353|M.leprae_Br4923          --------------MITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKES
MMAR_1772|M.marinum_M               -------------MSTIPDNAIAVVGMAGKFPGAKDVSTFWSNLRRGKES
MUL_2015|M.ulcerans_Agy99           -------------MSTIPDNAIAVVGMAGKFPGAKDVSTFWSNLRRGKES
Mflv_3390|M.gilvum_PYR-GCK          MTSGTRDSTSDSPQDSLPDNAIAVIGMAGRFPGAQSVSEFWRNLRGGVES
Mvan_3123|M.vanbaalenii_PYR-1       MTSGASNNT-----DELPDNAIAVIGMAGRFPGAGSVSEFWRNLRNGVES
MAB_2256|M.abscessus_ATCC_1997      WWAELDGESEASEVHEVRDDDVAVIGIAARVPGAASLDEFWTNLCAGEES
                                                         :*::.:. :.*** .   :*  *      

MAV_3107|M.avium_104                ----------------------GREVTRFAG---EAAEFDADFFNLSPRE
MSMEG_0408|M.smegmatis_MC2_155      IREVPEDRWDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDPEFFGISPRE
TH_4458|M.thermoresistible__bu      ITATPPERWDTDS---------VGDGTRWGGFLERIDGFDAGFFGISPRE
Mb2960|M.bovis_AF2122/97            IVTLSEQELRDAGVSDKTLA--DPAYVRRAPLLDGIDEFDAGFFGFPPLA
Rv2935|M.tuberculosis_H37Rv         IVTLSEQELRDAGVSDKTLA--DPAYVRRAPLLDGIDEFDAGFFGFPPLA
MLBr_02353|M.leprae_Br4923          IVTLSEQELRDNGVSDKALA--DPAYVRRAPLLDGIDEFDADFFGLPPLA
MMAR_1772|M.marinum_M               IVTLSEEELREAGVSDKTLA--DPSYVRRAPLVDGIDEFDADFFGFPPLA
MUL_2015|M.ulcerans_Agy99           IVTLSEEELREAGVSDKTLA--DPSYVRRAPLVDGIDEFDADFFGFPPLA
Mflv_3390|M.gilvum_PYR-GCK          IVDLSESELLAAGVTEQTLA--NRSYVRRAALMSGIEEFDADFFGFTPQA
Mvan_3123|M.vanbaalenii_PYR-1       IVDLPEDELLANGVTERTLS--NRSYVRRAGLMPGIDEFDADFFGFTPYA
MAB_2256|M.abscessus_ATCC_1997      LTRFTDEELLSAGVTPEELR--DPRLVRVRPILADVADFDTKFFGYAPSE
                                                              .*          **. **. .*  

MAV_3107|M.avium_104                AAAMDPRQRLALELAWELLEDAFIVAETLRGEA---------VSVYLGAM
MSMEG_0408|M.smegmatis_MC2_155      AVWIEPQQRLMLETVWEGLERAGYAPSDLRGSR---------TGVFTGVA
TH_4458|M.thermoresistible__bu      AVRIDPQQRLLLEVAWEALEDAGLVPDRLAGSR---------TGVFTGVS
Mb2960|M.bovis_AF2122/97            AQVLDPQHRLFLQCAWHALEDAGADPARFDGSIGVYGTSSPSGYLLHNLL
Rv2935|M.tuberculosis_H37Rv         AQVLDPQHRLFLQCAWHALEDAGADPARFDGSIGVYGTSSPSGYLLHNLL
MLBr_02353|M.leprae_Br4923          AQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPSGYLLHNLL
MMAR_1772|M.marinum_M               AQVLDPQHRLFLQCAWHALEDANCDPAKFDGSIGVYGTSSPSGYLLHNLL
MUL_2015|M.ulcerans_Agy99           AQVLDPQHRLFLQCAWHALEDANCDPAKFDGSIGVYGTSSPSGYLLHNLL
Mflv_3390|M.gilvum_PYR-GCK          AKALDPQHRLFLQTVFHAFEDAGYDPKGLEATVGVFGTSSTSGYLLHNLM
Mvan_3123|M.vanbaalenii_PYR-1       ARMLDPQHRLFLQTVFHAMEDAGYDPKGLEATVGVFGTSSSSGYLLHNLM
MAB_2256|M.abscessus_ATCC_1997      ARSIDPQQRLFLECAWEAVESAGYDLQRYDGSVGVFGGSAGSTYYRAVLS
                                    *  ::*::** *: .:. .* *        .                   

MAV_3107|M.avium_104                TDDYAALTLRDVPDNVDHHTFTGVSRGMIANRISYLLGLRGASMTVDSGQ
MSMEG_0408|M.smegmatis_MC2_155      ANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTAC
TH_4458|M.thermoresistible__bu      TYDYLHLQLSHP-ELIDAYSGTGTASSIAANRLSYVFDFRGPSLTLDSAC
Mb2960|M.bovis_AF2122/97            SHRDPNAVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTAC
Rv2935|M.tuberculosis_H37Rv         SHRDPNAVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTAC
MLBr_02353|M.leprae_Br4923          SHRDPHTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTAC
MMAR_1772|M.marinum_M               SHRDPNTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTAC
MUL_2015|M.ulcerans_Agy99           SHRDPNTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTAC
Mflv_3390|M.gilvum_PYR-GCK          SNYDPMMVIGQGASFDMVSLSLSNDKDHLATRVAHSYDLRGPALSVATAC
Mvan_3123|M.vanbaalenii_PYR-1       SNFDPMMVIGQGASFEMVNLSLQNDKDHLATRAAHQFDFRGPALSVATAC
MAB_2256|M.abscessus_ATCC_1997      TDYG------NLNGTEYLQTALATENDFLAPRVSYKLNLRGPSISLGTGC
                                    :         .               .  : * :.  .:.*.:::: :. 

MAV_3107|M.avium_104                SSSLVAVHLGCESVRSGQAPLAIAGGVHLNLADEIALLEREFGAVSVSGH
MSMEG_0408|M.smegmatis_MC2_155      SSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGR
TH_4458|M.thermoresistible__bu      SSSLVAVHQACRSLRDGECDLALAGGVNIMLSAGIGLNFTRAGVMATDGR
Mb2960|M.bovis_AF2122/97            SSSLVAVHLACLSLLSGECDMALAGGSSLCIPHRVGYFTSPGSMVSAVGH
Rv2935|M.tuberculosis_H37Rv         SSSLVAVHLACLSLLSGECDMALAGGSSLCIPHRVGYFTSPGSMVSAVGH
MLBr_02353|M.leprae_Br4923          SSSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPGSMVSAVGH
MMAR_1772|M.marinum_M               SSSLVAVHLACLSLLSGECDVALAGGSSLCVPHHVGYFTSPGSMVSAVGH
MUL_2015|M.ulcerans_Agy99           SSSLVAVHLACLSLLSGECDVALAGGSSLCVPHHVGYFTSPGSMVSAVGH
Mflv_3390|M.gilvum_PYR-GCK          SSSLVAVHLACQSILNGECDIALAGGSSLRIPNRVGYWYAQGSMVTPTGQ
Mvan_3123|M.vanbaalenii_PYR-1       SSSLVAVHLACQSLLNGECDIALAGGSSLRIPHHVGYWYEQGAMVSPTGQ
MAB_2256|M.abscessus_ATCC_1997      STSLVAIHLAVQSVLTGESDMALAGGASITFPQTAGYVATESGAISTSGR
                                    *::***:* .  ::  *:. :*:***  : ..            ::  *:

MAV_3107|M.avium_104                TYAFDRRADGYVRGEGGGLVLLKPLAAARRDGDRIHAVIRATAVGNAGHG
MSMEG_0408|M.smegmatis_MC2_155      CKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGAS
TH_4458|M.thermoresistible__bu      CKTFDARADGWVRGEGAGIVVLKPLREALADEDPIYAVIRGSAVNQDGRT
Mb2960|M.bovis_AF2122/97            CRPFDVRADGTVFGSGVGLVVLKPLAAAIDAGDRIHAVIRGSAINNDGSA
Rv2935|M.tuberculosis_H37Rv         CRPFDVRADGTVFGSGVGLVVLKPLAAAIDAGDRIHAVIRGSAINNDGSA
MLBr_02353|M.leprae_Br4923          CRPFDVRADGTVFGSGVALVALKPLQAAIDASDRIHAVILGSAINNDGSM
MMAR_1772|M.marinum_M               CRPFDVRSDGTVFGSGVAMVVLKPLQAAIDAGDRIHAVIRGSAINNDGSA
MUL_2015|M.ulcerans_Agy99           CRPFDVRSDGTVFGSGAAMVVLKPLQAAIDAGDRIHAVIRASAINNDGSA
Mflv_3390|M.gilvum_PYR-GCK          CRPFDVRADGTVFGSGVGVLVLKALEDAVADGDRIHAVIRGSALNNDGAT
Mvan_3123|M.vanbaalenii_PYR-1       CRPFDVRSDGTIFASGVGVVVLKALADAIDDGDHIHAVIRGSALNNDGST
MAB_2256|M.abscessus_ATCC_1997      CRAFDASADGTLVGDGIGIVLLKRASNAVADGDSILGIIRGTAVNNDGGN
                                      .**  :** : ..* .:: **    *    * : .:* .:::.: *  

MAV_3107|M.avium_104                APAQTLPSAAAEADVIGRALAEAGLGGADIDYVEAHGTGTRVGDAVETQA
MSMEG_0408|M.smegmatis_MC2_155      S-GLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQA
TH_4458|M.thermoresistible__bu      N-GLMAPSRTAQEVVLTDAYRRAGVSPGVVQYVEAQGIGTPVGDAIEVGA
Mb2960|M.bovis_AF2122/97            KMGYAAPNPAAQADVIAEAHAVSGIDSSTVSYVECHGTGTPLGDPIEIQG
Rv2935|M.tuberculosis_H37Rv         KMGYAAPNPAAQADVIAEAHAVSGIDSSTVSYVECHGTGTPLGDPIEIQG
MLBr_02353|M.leprae_Br4923          KMGYAAPNPAAQADVIAEAHAVAGIDSSTVSYVETHGTGTPLGDPIEIQG
MMAR_1772|M.marinum_M               KMGYAAPNPAAQADVIAEAHAVSGIDASTVSYVECHGTGTPLGDPIEIQG
MUL_2015|M.ulcerans_Agy99           KMGYAAPNPAAQADVIAEAHAVSGIDASTVSYVECHGTGTPLGDPIEIQG
Mflv_3390|M.gilvum_PYR-GCK          KMTYAAPNALGQAEVIAEAHAIAGVDASTITYVETHGTGTPLGDPIEVEG
Mvan_3123|M.vanbaalenii_PYR-1       KMTYAAPNALGQAEVIAEAHAIAGVDASSITYVETHGTGTPLGDPIEIEG
MAB_2256|M.abscessus_ATCC_1997      KAGFAAPSISGQVEVITEALAVAEVPAQTVDYVETHGTGTPLGDPIEIAA
                                          *.  .:  ::  :   : :    : *:* :* ** :**.:*  .

MAV_3107|M.avium_104                LGRIFAER---SHHPVSVGSVKTNIGHAASAAGIAGLLKAVLAIEHAAIP
MSMEG_0408|M.smegmatis_MC2_155      AAAAYGAGRD-ADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLP
TH_4458|M.thermoresistible__bu      LGTVLAEDRP-PDSPCLIGSVKTNIGHLEAAAGIAGLIKVALALRHRMIP
Mb2960|M.bovis_AF2122/97            LRAAFEVSQTSRSAPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKALP
Rv2935|M.tuberculosis_H37Rv         LRAAFEVSQTSRSAPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKALP
MLBr_02353|M.leprae_Br4923          LKTAFEVSQIPRPGPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNKAIP
MMAR_1772|M.marinum_M               LRTAFEASETTRTGPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNRAIP
MUL_2015|M.ulcerans_Agy99           LRTAFEASETTRTGPCVLGSVKSNIGHLEVAAGIAGLIKTILCLKNRAIP
Mflv_3390|M.gilvum_PYR-GCK          LRQAFELAEDERSAPCYLGSVKSNIGHLETAAGIAGLIKAILCLEHKAIP
Mvan_3123|M.vanbaalenii_PYR-1       LRQAFELSEETRSAPCYLGSVKSNIGHLETAAGIAGLIKAILCLEHKAIP
MAB_2256|M.abscessus_ATCC_1997      LHKAFREAGDTRTQACRLGTLKPNIGHTGPASGVLALIKVLLAFQHRMYP
                                                  .  :*::*.****   *:*  .*:*. *.:.:   *

MAV_3107|M.avium_104                PNLHFERPDPDIDLNRLGLRVNTALAPWPDRGG-PRRAGVSSFGMGGTNA
MSMEG_0408|M.smegmatis_MC2_155      QSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR-VRRAGVSSFGFTGTNA
TH_4458|M.thermoresistible__bu      PTLNFTEPNPTIEFDKLPVRVAQTLTPWPDDSG-RAVAGVSAFGFGGTNA
Mb2960|M.bovis_AF2122/97            ATLHYTSPNPELRLDQSPFVVQSKYGPWECDG--VRRAGVSSFGVGGTNA
Rv2935|M.tuberculosis_H37Rv         ATLHYTSPNPELRLDQSPFVVQSKYGPWECDG--VRRAGVSSFGVGGTNA
MLBr_02353|M.leprae_Br4923          ATLHYTSPNRELRLDQTPFVVQSNYGPWKWDG--VRRAGVSSFGVGGTNV
MMAR_1772|M.marinum_M               ATLHYTSPNPELRLEQSPFVVQNKYGPWEWDG--VLRAGVSSFGVGGTNA
MUL_2015|M.ulcerans_Agy99           ATLHYTSPNPELRLEQSPFVVQNKYGPWEWDG--VLRAGVSSFGVGGTNA
Mflv_3390|M.gilvum_PYR-GCK          ATLHYTSPNPELHLDRGPFRVRAQDGPWESDG--IRRAGVSSFGVGGTNA
Mvan_3123|M.vanbaalenii_PYR-1       ATLHYTSPNPELHLDRGPFRIRSSDGPWESDG--IRRAGVSSFGVGGTNA
MAB_2256|M.abscessus_ATCC_1997      PAANFTAPNPQIEFSKSPFYVGTRLRRWNAPGGKPRRAGVSSYSMGGTNA
                                       ::  *.  :  .   . :      *   .     ****::.. ***.

MAV_3107|M.avium_104                HVIVEQDAAQQNPTPAS--APADVALP--------WVLSARSERALALQA
MSMEG_0408|M.smegmatis_MC2_155      HVLVEEAPPQLHTADAAPVEPAATAEAGTDDSPQVLALSARSPEALVELA
TH_4458|M.thermoresistible__bu      HVVLAEAPQVRAAATADDHADGFVEILP---------LSARSQAALDALA
Mb2960|M.bovis_AF2122/97            HVVLEEAPAEASEVSAHAEPAGPQVIL----------LSAQTAAALGESR
Rv2935|M.tuberculosis_H37Rv         HVVLEEAPAEASEVSAHAEPAGPQVIL----------LSAQTAAALGESR
MLBr_02353|M.leprae_Br4923          HVVLEEASVEASTVAAS---TGPQVIL----------LSAQTAAALGESR
MMAR_1772|M.marinum_M               HVVLEEAP----TVPAHDEPAGPQVLL----------LSAQTAAALTESR
MUL_2015|M.ulcerans_Agy99           HVVLEEAP----TVPAHDEPAGPQVLL----------LSAQTAAALTESR
Mflv_3390|M.gilvum_PYR-GCK          HIILEEAP-VAPARAQTSSPARPSVLV----------LSARTQEALEDSR
Mvan_3123|M.vanbaalenii_PYR-1       HIVLEEAP-TAPVPAPRSG---PQVLV----------LSARTEETLAQSR
MAB_2256|M.abscessus_ATCC_1997      HAVLQEPP---RAELPPKSQEGAHLLV----------LSARTAPALEAAR
                                    * :: : .                             ***::  :*    

MAV_3107|M.avium_104                QRLSAHLAERPQASPLDVGWSLVSARAVFEHRAVLVGCERGVLATGLAGV
MSMEG_0408|M.smegmatis_MC2_155      RRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVERAREGLAAL
TH_4458|M.thermoresistible__bu      ERYESALTG--GVPPADLCHTAGARRAHHDHRLAVVGASRAELIGALAAY
Mb2960|M.bovis_AF2122/97            TALAAALETQDGPRLSDVAYTLAR-RRKHNVTMAAVVHDREHAATVLRAA
Rv2935|M.tuberculosis_H37Rv         TALAAALETQDGPRLSDVAYTLAR-RRKHNVTMAAVVHDREHAATVLRAA
MLBr_02353|M.leprae_Br4923          EALATVLEKPGAPDLSDVAYTLAG-RRKHNITMAAVVRDREHAVTVLRAA
MMAR_1772|M.marinum_M               TALAEVLERSDSPDLSDVAYTLSR-RRKHNVTMAAVVSDREEAATALRAA
MUL_2015|M.ulcerans_Agy99           TALAEVLGRSDSPDLSDVAYTLSR-RRKHNVTMAAVVSDREEAATALRAA
Mflv_3390|M.gilvum_PYR-GCK          ATLARELGENAEISLPDVAYTLGR-RRKEPIRLAAVVRDQANAATVLSAA
Mvan_3123|M.vanbaalenii_PYR-1       AALAAELSEVDEISLPDAAYTLTH-RRKDPVRLAAVVHDQENAATVLSAA
MAB_2256|M.abscessus_ATCC_1997      KNLAHHLARHPEQDLAAVAATLRLGRRAFSHRFAAVCADRPEALQVLEGT
                                          *             :    *       . *  .       * . 

MAV_3107|M.avium_104                ASGRPDAATVVG--------------RARATGKTVLVFPGQGSQTLGMGR
MSMEG_0408|M.smegmatis_MC2_155      AEGRTPAGVVRG--------------EHVHRPTTAWLFTGQGSQYPGMAR
TH_4458|M.thermoresistible__bu      RRGEPHPGVFTGR------------SQSGHRSGVVFVFSDEGSQWRGMAQ
Mb2960|M.bovis_AF2122/97            EHD----NVFVGEAAHDGEHGDRADAAPT-SDRVVFLFPGQGAQHVGMAK
Rv2935|M.tuberculosis_H37Rv         EHD----NVFVGEAAHDGEHGDRADAAPT-SDRVVFLFPGQGAQHVGMAK
MLBr_02353|M.leprae_Br4923          EHD----NVFVGESGADTGRSAAASITTLGSDRVVFLFPGQGAQHVGMAK
MMAR_1772|M.marinum_M               DND----SIFVGESVAG-----VADATAAAAERVVFLFPGQGAQHVGMAK
MUL_2015|M.ulcerans_Agy99           DND----SIFVGESVAG-----VADATAAAAERVVFLFPGQGAQHVGMAK
Mflv_3390|M.gilvum_PYR-GCK          ETDGATDNVFIGR--------GHPDWDSSATDRIAFLFPGQGAQHIGMAR
Mvan_3123|M.vanbaalenii_PYR-1       ETD----NVFIGR--------AVPDLQDSA-ERVAFLFPGQGAQHVGMAR
MAB_2256|M.abscessus_ATCC_1997      GHAP-----------------FRTGTAADKPRPVVFLFPGQGSQFSGMGE
                                                                      . :*..:*:*  **..

MAV_3107|M.avium_104                QLYERFVVFARALDEAVAVVDEHSRLSVREVMWGAD-----PELLQSTEF
MSMEG_0408|M.smegmatis_MC2_155      ELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRE--TADLLQHTSF
TH_4458|M.thermoresistible__bu      RLYAEDQVFRTALAECDRALRRHMEISPLSELLADP----SHSRMDEVTI
Mb2960|M.bovis_AF2122/97            GLYDTEPVFAQHFDTCAAGFRDETG-IDLHAEVFDG----TATDLERIDR
Rv2935|M.tuberculosis_H37Rv         GLYDTEPVFAQHFDTCAAGFRDETG-IDLHAEVFDG----TATDLERIDR
MLBr_02353|M.leprae_Br4923          GLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNG----TAIDLERIDR
MMAR_1772|M.marinum_M               GLYETEPVFAEHFDACAAGFRAEMG-VDLNAEIFNG----TATDLERIDR
MUL_2015|M.ulcerans_Agy99           GLYETEPVFAEHFDACAAGFRAEMG-VDLNAEIFNG----TGTDLERIDR
Mflv_3390|M.gilvum_PYR-GCK          GLHDNEPVFARYFDECATAFSDEMG-FDLRAEIFDG----VGRNLEHTDR
Mvan_3123|M.vanbaalenii_PYR-1       GLYDNEPVFKRHFDECATAFSDDMG-YDLRAEIFDG----VGRNLEHTDR
MAB_2256|M.abscessus_ATCC_1997      QLYTTSSMYRRHIDECATLFEPLIG-VDLRTMLCAEGDEATDAALMQTRL
                                     *.    ::   .  .   .                        :     

MAV_3107|M.avium_104                AQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVAGVLSLRDAAR
MSMEG_0408|M.smegmatis_MC2_155      AQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGAR
TH_4458|M.thermoresistible__bu      ASPALFAVQVALAALWQSWGVEPAAVIGHRMGEVAAAHVAGVLGLDDAAA
Mb2960|M.bovis_AF2122/97            SQPALFTVEYALAKLVDTFGVRAGAYIGYSTGEYIAATLAGVFDLQTAIK
Rv2935|M.tuberculosis_H37Rv         SQPALFTVEYALAKLVDTFGVRAGAYIGYSTGEYIAATLAGVFDLQTAIK
MLBr_02353|M.leprae_Br4923          SQPALFTVEYALAKLVESFGVGAGAYIGYSTGEYIAATLAGVFDLETAIK
MMAR_1772|M.marinum_M               SQPALFTVEYALAKLVDTYGVRAGAYIGYSTGEYIAATLAGVFDLETAIK
MUL_2015|M.ulcerans_Agy99           SQPALFTVEYALAKLVDTYGVRAGAYIGYSTGEYIAATLAGVFDLETAIK
Mflv_3390|M.gilvum_PYR-GCK          AQPALFTVEYALARLIQSYGVEPAIMAGHSIGEYPAATLAGVFDLDTAVK
Mvan_3123|M.vanbaalenii_PYR-1       AQPALFTVEYALAKLVQSYGVEPAIMAGHSIGEYPAATIAGVFDLDTAVK
MAB_2256|M.abscessus_ATCC_1997      TQPALFTVGYALSQLLGAWGVQPVAMLGHSIGELVAACAAGVFTIEEAVQ
                                    :.****..  .*: *  : .: .    *:  *:  **  ***: :  .  

MAV_3107|M.avium_104                LVAARGALMAALPPGGVMVAVTATEAQVAPLVGGG---VSIAAVNGPDAV
MSMEG_0408|M.smegmatis_MC2_155      LMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFP-RVSVGAYNGP-NT
TH_4458|M.thermoresistible__bu      LLCGRTRLSRLASTG-----------------------------------
Mb2960|M.bovis_AF2122/97            TVSLRARLMHESPPGAMVAVALGPDDVTQYLPP----EVELSAVNDPGNC
Rv2935|M.tuberculosis_H37Rv         TVSLRARLMHESPPGAMVAVALGPDDVTQYLPP----EVELSAVNDPGNC
MLBr_02353|M.leprae_Br4923          TVSLRARLMHESPPGAMVAVALGPEDITEYLAEYSAKGVELSAVNDPGNC
MMAR_1772|M.marinum_M               TVSLRARLMHESPPGAMVAVAVGPDEIAQYLGD----GVELSAVNDPGNC
MUL_2015|M.ulcerans_Agy99           TVSLRARLMHESPPGAMVAVAVGPDDFAQYLGD----GVELSAVNDPGNC
Mflv_3390|M.gilvum_PYR-GCK          VVATRAKLMHAAPRGVMIAVPLSPDAVAEYLTP----DVDIATINDPGSC
Mvan_3123|M.vanbaalenii_PYR-1       VVSKRAKLMHAAPRGVMVAVPLSPEAVAEHLTP----DVDVATINDPGSC
MAB_2256|M.abscessus_ATCC_1997      LAARRGDLIQQCPSGAMAAVGGSLEVVSALLPEG----VSVAAVNGPEQI
                                      . *  :    . *                                   

MAV_3107|M.avium_104                VLSGEQEAVSAVAERLAGSGARVHRLAVSHAFHSALMEPMLDGFAAAAAG
MSMEG_0408|M.smegmatis_MC2_155      VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFEAYAAQ
TH_4458|M.thermoresistible__bu      --------------------------------------AVREGLDGLLAN
Mb2960|M.bovis_AF2122/97            VVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHTSAMDPMLGQFQEFLSR
Rv2935|M.tuberculosis_H37Rv         VVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHTSAMDPMLGQFQEFLSR
MLBr_02353|M.leprae_Br4923          VVAGPKDQIRAFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSR
MMAR_1772|M.marinum_M               VVAGPKDEIRAFSQRLNEAGIPVRRVRATHAFHSSSMEPMLGEFQEFLSR
MUL_2015|M.ulcerans_Agy99           VVAGPKDEIRAFSQRLNEAGIPVRRVRATHAFHSSSMEPMLGEFQEFLSR
Mflv_3390|M.gilvum_PYR-GCK          VVAGTDEAIRAFQAGLAEKGVAARRVRTAHAFHSRLMDPVVAEFTAFLSG
Mvan_3123|M.vanbaalenii_PYR-1       VVAGSEEAIRTFQAALAEKGVAARRVRTSHAFHSRLMDPVVAEFGAFLSG
MAB_2256|M.abscessus_ATCC_1997      VVAGREEGIEALLSTGANVGVRCTRLPVNRGFHSALVDPAVSSFSAAVAR
                                                                          .    :    : 

MAV_3107|M.avium_104                IEPRPPRIPLVSNLTG-QLAGPGYGTPQYWVEHVRRPVRFVDGVRLAESQ
MSMEG_0408|M.smegmatis_MC2_155      FQFAAPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAAL
TH_4458|M.thermoresistible__bu      LRPDDPRIPLYSTVTGDAVTGRGFG-AAHWMENLHSPVRFSAAVRRLLGR
Mb2960|M.bovis_AF2122/97            QQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQISSPIRFADELDVVLAA
Rv2935|M.tuberculosis_H37Rv         QQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQISSPIRFADELDVVLAA
MLBr_02353|M.leprae_Br4923          QQLRVPNTPLLSNLTGTWMSEQQVTDPENWTRQISSTIRFADELDVVLSQ
MMAR_1772|M.marinum_M               QQLRAPQTPLLSNLTGTWLSEQQVTDPATWARQISSTVRFADELDVVLSQ
MUL_2015|M.ulcerans_Agy99           QQLRAPQTPLLSNLTGTWLSEQQVTDPATWARQISSTVRFADELDVVLSQ
Mflv_3390|M.gilvum_PYR-GCK          LTLREPQIPLLSNVTGTTMSASEATNPSTWARQIRATVRFADELDALLAA
Mvan_3123|M.vanbaalenii_PYR-1       VTLREPQIPLLSNITGTTMTAAEATNPSTWARQIRATVRFADELDALLAA
MAB_2256|M.abscessus_ATCC_1997      MRLQQPQVPFISNVTGTWITGAQATEPEYWGRQLRETVQFARGLTTLCAE
                                         *  *: .. **  ::      .  * .:   .::*   :    . 

MAV_3107|M.avium_104                -GAGVFLEVGPGAALTA--AVDQSLSTEGAT--AIATLPKDRPETESALH
MSMEG_0408|M.smegmatis_MC2_155      -GCSVLMEIGPQPVLTG--AAVQVWPEHMAAPRAVASLRKGVADRRQIAD
TH_4458|M.thermoresistible__bu      -GHDAFLEISAHPMLLS--AVQEDAADLGRSCTTLVSMRRGECGRDVLMT
Mb2960|M.bovis_AF2122/97            -PSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRLMRHPLQDVDDRDTFLR
Rv2935|M.tuberculosis_H37Rv         -PSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRLMRHPLQDVDDRDTFLR
MLBr_02353|M.leprae_Br4923          -SGRVLVEVGPGGSLTGSAMRHPRWSSGHRAVRLMRHPLQNVDDHDTFLR
MMAR_1772|M.marinum_M               -PNRILVEIGPGGSLTGSAIRHPKWSDGHRSVRLMRHPIQNLDDRETFLR
MUL_2015|M.ulcerans_Agy99           -PNRILVEIGPGGSLTGSAIRHPKWSDGHRSVRLMRHPIQNLDDRETFLR
Mflv_3390|M.gilvum_PYR-GCK          -PDRVLVEVGPGGTLTSSAGRHPRWSERHRAVRLMRHQAQNRSDDDTFHL
Mvan_3123|M.vanbaalenii_PYR-1       -PDRVLVEVGPGGTLTSSAGRHPKWTERHRAVRLMRHQAQNRNDHDTFLL
MAB_2256|M.abscessus_ATCC_1997      YPDALLVEVGPGHTLRGIVAAN---TPASEVVSMLGDRTG--DSATVALA
                                         ::*:..   * .        .        :               

MAV_3107|M.avium_104                AAGHLFTRGHRLDWAGVFAG--LPARRVDLPTYAFARERFWLGGASLAGA
MSMEG_0408|M.smegmatis_MC2_155      ALASAYVGGHRPDFAAVHR---QPRRPVELPTYPFQRRRFWPKASSIAVD
TH_4458|M.thermoresistible__bu      SLAALYASGHAVDWARVHP---HGSHCTAAPTYPWQRQRFWLDIDRCDTG
Mb2960|M.bovis_AF2122/97            ALGELWSAGVEVDWTPR---RPAVPHLVSLPGYPFARQRHWVEPNHTVWA
Rv2935|M.tuberculosis_H37Rv         ALGELWSAGVEVDWTPR---RPAVPHLVSLPGYPFARQRHWVEPNHTVWA
MLBr_02353|M.leprae_Br4923          ALGELWSAGIEVDWAPQ---RSVMPHLVSLPGYPFARQRHWVEPRYTIWA
MMAR_1772|M.marinum_M               ALGELWSAGVDVDWTPR---RAASPRIVSLPGYPFARQRHWVEPKHMAWA
MUL_2015|M.ulcerans_Agy99           ALGELWSAGVDVDWTPR---RAASPRIVSLPGYPFARQRHWVEPKHMAWA
Mflv_3390|M.gilvum_PYR-GCK          ALGQLWAADVDVDWTQGDQDAADARTLVTLPGYPFARQRHWVEYN----A
Mvan_3123|M.vanbaalenii_PYR-1       ALGQLWAADVEVDFNQG---AEEDRTLITLPGYPFAKQRHWVEHN----A
MAB_2256|M.abscessus_ATCC_1997      AAGRLWAGGAELAWQHFG----ASRPRVPLPTYPFERERLWMSPP-----
                                    : .  :  .    :                * *.: :.* *         

MAV_3107|M.avium_104                PAGAAP--VGGG--------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      GGTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATY
TH_4458|M.thermoresistible__bu      DGAGTGGTAERTVVPAP---------------------------------
Mb2960|M.bovis_AF2122/97            QAPGANNGSPAGTADGSTA--ATVDAARNG--------------------
Rv2935|M.tuberculosis_H37Rv         QAPGANNGSPAGTADGSTA--ATVDAARNG--------------------
MLBr_02353|M.leprae_Br4923          QIPGASSGSPVDSSVDS----ATVEGVRGG--------------------
MMAR_1772|M.marinum_M               QIPTASNGSSVGAKLGSGADSGIRGGAQTG--------------------
MUL_2015|M.ulcerans_Agy99           QIPTASNGSSVGAKLGSGADSGIRGGAQTG--------------------
Mflv_3390|M.gilvum_PYR-GCK          SSAWVANGSGAAGVSATGAQAGSAAGGAGG--------------------
Mvan_3123|M.vanbaalenii_PYR-1       NAAWLAGGAGADGTAAAAGSAGVAPVAAGG--------------------
MAB_2256|M.abscessus_ATCC_1997      ---RSVLDKPVQAPIAPAVQVPLVTASTQT--------------------
                                                                                      

MAV_3107|M.avium_104                ----------------------------------------TRAPELAHRL
MSMEG_0408|M.smegmatis_MC2_155      AAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQI
TH_4458|M.thermoresistible__bu      ----------------------------------LPAPSASAAPTVDEVL
Mb2960|M.bovis_AF2122/97            -----------------------------------ESQTEVTLQRIWSQC
Rv2935|M.tuberculosis_H37Rv         -----------------------------------ESQTEVTLQRIWSQC
MLBr_02353|M.leprae_Br4923          -----------------------------------ESQTEATLQRIWSQC
MMAR_1772|M.marinum_M               -----------------------------------ESQTEDVLQRIWSQC
MUL_2015|M.ulcerans_Agy99           -----------------------------------ESQTEDVLQRIWSQC
Mflv_3390|M.gilvum_PYR-GCK          -----------------------------------GSSVEASLQRIWAQC
Mvan_3123|M.vanbaalenii_PYR-1       -----------------------------------TSTVEAKLARIWSQC
MAB_2256|M.abscessus_ATCC_1997      -----------------------------------DVPDAAVVEQIWCEA
                                                                                 :    

MAV_3107|M.avium_104                HALPRDEQQRVLRELVCEHAAAVLGHPGGDAIDPD---------------
MSMEG_0408|M.smegmatis_MC2_155      HSRPYGER-GADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMR
TH_4458|M.thermoresistible__bu      LCADQRERRELLESYLRDRVAAELGVLPPLLDVAAP--------------
Mb2960|M.bovis_AF2122/97            LGVSSVDRNANFFDLGGDSLMAISIAMAAANEGLTITPQDLYEYPTLASL
Rv2935|M.tuberculosis_H37Rv         LGVSSVDRNANFFDLGGDSLMAISIAMAAANEGLTITPQDLYEYPTLASL
MLBr_02353|M.leprae_Br4923          LGVSSVDRNANFFDLGGDSLMAISISMAAANEGMTITPQDMYEHPTLASL
MMAR_1772|M.marinum_M               LGVGSVDRNANFFDMGGDSLMAISIAMSAANEGLTITPQDLYEHPTLASL
MUL_2015|M.ulcerans_Agy99           LGVGSVDRNANFFDMGGDSLMAISIAMSAANEGLTITPQDLYEHPTLASL
Mflv_3390|M.gilvum_PYR-GCK          LGVNEIDRHANFFEIGGDSLVAISVAMTAGHAGLDLTPQDLYENQTVASL
Mvan_3123|M.vanbaalenii_PYR-1       LGLSDIDRNANFFEIGGDSLIAISVAMTAGHEGLDLTPQDLYENQTVAAL
MAB_2256|M.abscessus_ATCC_1997      LGVPSVESDDNFFDLGGDSLIAARVVTAIGER-----------CHIKVSV
                                          :      .   :                                

MAV_3107|M.avium_104                -----RAFADLGFDS----------------------LIGVELRNRLTTH
MSMEG_0408|M.smegmatis_MC2_155      PQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSE
TH_4458|M.thermoresistible__bu      -------LSTLGIDS----------------------LTAAELRARVERD
Mb2960|M.bovis_AF2122/97            TAAVDASFASSGLAKP----------------------PEAQANPAVPPN
Rv2935|M.tuberculosis_H37Rv         TAAVDASFASSGLAKP----------------------PEAQANPAVPPN
MLBr_02353|M.leprae_Br4923          TAAVDASFASSGLAKP----------------------PEAAAHPAVPPN
MMAR_1772|M.marinum_M               TAAIDASFASSGLAKP----------------------PEADANPAVPPN
MUL_2015|M.ulcerans_Agy99           TAAIDASFASSGLAKP----------------------PEADANPAVPPN
Mflv_3390|M.gilvum_PYR-GCK          AKVLTARYAEGGLARQS---------------------VDDSTSPPVPPN
Mvan_3123|M.vanbaalenii_PYR-1       AKVLTARYAEGGLARQT---------------------LDDAVNPPVPPN
MAB_2256|M.abscessus_ATCC_1997      AELWDQGATLADLAELV---------------------ERRAINSKVGEQ
                                            :   :                                 :  .

MAV_3107|M.avium_104                TGTALSRTLIFDYPTPAALADHLRQQLLHD--------------------
MSMEG_0408|M.smegmatis_MC2_155      PMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAEKMPRRF
TH_4458|M.thermoresistible__bu      LGIVIPVAQLLNGPSVSDLAEWISTTMVGFG-------------------
Mb2960|M.bovis_AF2122/97            VTYFLDRGLRDTGRCRVPLILRLDPKIGLPD-------------------
Rv2935|M.tuberculosis_H37Rv         VTYFLDRGLRDTGRCRVPLILRLDPKIGLPD-------------------
MLBr_02353|M.leprae_Br4923          IAYFLERGLCDTGRWRVPLILRLDPKIGSDD-------------------
MMAR_1772|M.marinum_M               IAYFLDRGLRDTGRWRVPLILRLDPQVGPED-------------------
MUL_2015|M.ulcerans_Agy99           IAYFLDRGLRDTGRWRVPLILRLDPQVGPED-------------------
Mflv_3390|M.gilvum_PYR-GCK          VAYFLEHGLRDVGRWRIPVILGLRSDVGEDD-------------------
Mvan_3123|M.vanbaalenii_PYR-1       VAYFLEHGLRDIGRWRIPVILGLRSDVGEDD-------------------
MAB_2256|M.abscessus_ATCC_1997      LK------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                ------EDPESDDE-------------RIWSALRRIPLRELRRTGLLDKL
MSMEG_0408|M.smegmatis_MC2_155      YCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGL
TH_4458|M.thermoresistible__bu      -----STTPEPESAG---------VPGRSRPPDGAVASGSGDGGRWIELL
Mb2960|M.bovis_AF2122/97            ------IRAVLTAVVNHHDALRLHLVGNDGIWEQHIAAPAEFTGLSNRSV
Rv2935|M.tuberculosis_H37Rv         ------IRAVLTAVVNHHDALRLHLVGNDGIWEQHIAAPAEFTGLSNRSV
MLBr_02353|M.leprae_Br4923          ------IRAVLTAVVNHHDVLRLSLVDNDGMWEQHIAATGEFTRLLTQTL
MMAR_1772|M.marinum_M               ------IRAVLSAVTNHHDALRLRLVENGGVWEQHIAAPADFTELATRQL
MUL_2015|M.ulcerans_Agy99           ------IRAVLSAVTNHHDALRLRLVENGGVWEQHIAAPADFTELATRQL
Mflv_3390|M.gilvum_PYR-GCK          ------VRAVLTAVTDAHDVLRVRLVERSGIWDQIIAEPGEFTELASREL
Mvan_3123|M.vanbaalenii_PYR-1       ------VRAVLTAVTEVHDALRVHLVERAGTWDQHIAEPGEFTELVARQL
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                ----------------------------LLLAGMPETAT-----------
MSMEG_0408|M.smegmatis_MC2_155      GGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRN
TH_4458|M.thermoresistible__bu      N-------------------------------------------------
Mb2960|M.bovis_AF2122/97            PDG--------------------------VAAGSPEERAAVLGILAELLE
Rv2935|M.tuberculosis_H37Rv         PNG--------------------------VAAGSPEERAAVLGILAELLE
MLBr_02353|M.leprae_Br4923          PDG--------------------------VAAGSAEERAVVSSILAELIA
MMAR_1772|M.marinum_M               PGD--------------------------LAAGEADEHGAVSNIVAELIA
MUL_2015|M.ulcerans_Agy99           PDD--------------------------LAADEADEHSAVSNIVAELIA
Mflv_3390|M.gilvum_PYR-GCK          PSG--------------------------VAAGSPQEREAVLAFLDEQVR
Mvan_3123|M.vanbaalenii_PYR-1       PEG--------------------------LAAGSPQEREAVLGFLDEQVR
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                TDAKIS------------------------------DADIDSLSPDALIA
MSMEG_0408|M.smegmatis_MC2_155      TDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKESGSASAESARLEAEIT
TH_4458|M.thermoresistible__bu      -----------------------------------QMPEVSDDTVDELLR
Mb2960|M.bovis_AF2122/97            DQTDPNAPLAAVHIAAAHGGPHYLCLAIHAMVT----DDSSRQILATDIV
Rv2935|M.tuberculosis_H37Rv         DQTDPNAPLAAVHIAAAHGGPHYLCLAIHAMVT----DDSSRQILATDIV
MLBr_02353|M.leprae_Br4923          SQSDLNEPLTAVQITTAHGGPHYLGLAVHQMVI----DDASRQILGTDII
MMAR_1772|M.marinum_M               EQGDSNAPLIAVHVTAPNGGAQYLGLALHEMVA----DDASRQLLGADII
MUL_2015|M.ulcerans_Agy99           EQGDSNAPLIAVHVTAPNGGAQYLGLALHETVA----DDASRQLLGADII
Mflv_3390|M.gilvum_PYR-GCK          EH-QVVVPLTATLIRSGSGGPSYLALSLHGIAGDVSGDSASRDVLLTDLF
Mvan_3123|M.vanbaalenii_PYR-1       EH-QVVVPLAATFIRGVTGGPSYLALSLHGIAG----DDVSRDVLLTDVF
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                MALNSADDDEAE--------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      NLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTT
TH_4458|M.thermoresistible__bu      QLLAAGENHDDTQLH-----------------------------------
Mb2960|M.bovis_AF2122/97            TAFGQRLAGEEITLEPVSTGWREWSLRCAALATHPAALDTRSYWIENSTK
Rv2935|M.tuberculosis_H37Rv         TAFGQRLAGEEITLEPVSTGWREWSLRCAALATHPAALDTRSYWIENSTK
MLBr_02353|M.leprae_Br4923          TAFGQRLAGEEITLEPVTTGWREWSLRCAALATHPAALDTRSFWIENANK
MMAR_1772|M.marinum_M               TAFAQRLGDQEIKLDPVTTGWRDWSVRCAALATHPAALDTRSYWIEQSTK
MUL_2015|M.ulcerans_Agy99           TAFAQRLDDQEIKLDPVTTGWRDWSVRCAALATHPAALDTRSYWIEQSTK
Mflv_3390|M.gilvum_PYR-GCK          TAFNQRMAGEEIVLAPVTASWREWSQRCAGLAGHPAVLDSRDYWLQTAHR
Mvan_3123|M.vanbaalenii_PYR-1       TAFSQRMAGEEIVLAPVPASWREWSQRCAGLASHPAVLDSRDYWLQTAGA
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      INEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPEIAVRQGKLLASRL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            ATLWLADALPNAHTAHPPRADELTKLSSTLSVEQTSELDDGRRRFRRS--
Rv2935|M.tuberculosis_H37Rv         ATLWLADALPNAHTAHPPRADELTKLSSTLSVEQTSELDDGRRRFRRS--
MLBr_02353|M.leprae_Br4923          VNLWLADVSLNTDVIQPPGADDLIRMPCTLSVEQTSELDDARRRFRRS--
MMAR_1772|M.marinum_M               ANLWLTDG----DAAQPPSATDLTKLPSVLNAEQTSELDDARRRFRRS--
MUL_2015|M.ulcerans_Agy99           ANLWLTDG----DAAQPPSATDLTKLPSVLNAEQTSELDDARRRFRRS--
Mflv_3390|M.gilvum_PYR-GCK          STLRVAGG----EPADRPGAADLERLSTMLSAAETGEFDDARRRLRLS--
Mvan_3123|M.vanbaalenii_PYR-1       STLRIAGP----EHSERPGVDDVTRLSTALSAAETGEIDDARRRLRLP--
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      LPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPDEGYVQVRVE
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            -----IQTILLAALGRTIAQTVGEGVVAVELEGEGRSVLRPDVDLRRTVG
Rv2935|M.tuberculosis_H37Rv         -----IQTILLAALGRTIAQTVGEGVVAVELEGEGRSVLRPDVDLRRTVG
MLBr_02353|M.leprae_Br4923          -----IQAIVLAALGRTIAQTVGDGVVAVELEGEGRSVLRPDVDVRRTIG
MMAR_1772|M.marinum_M               -----IQTILLAALGRTIAQTVGDGVVAVELDGEGRSVLRPDVDVRRTVG
MUL_2015|M.ulcerans_Agy99           -----IQTILLAALGRTIAQTVGDGVVAVELDGEGRSVLRPDVDVRRTVG
Mflv_3390|M.gilvum_PYR-GCK          -----AEEILLAALGRAVAVTVGEGAVAVDLGGRGRSVLKPDVDLARTVG
Mvan_3123|M.vanbaalenii_PYR-1       -----VEEILLAALGRAVAATVGEGAVSVDLGGRGRSVLKPDVDLQRTVG
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      AAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGS
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            WFTTYYPVPLACATGLG--ALAQLDAVHNTLKSVPHYGIGYGLLRYVYAP
Rv2935|M.tuberculosis_H37Rv         WFTTYYPVPLACATGLG--ALAQLDAVHNTLKSVPHYGIGYGLLRYVYAP
MLBr_02353|M.leprae_Br4923          WFTNYYPIPLVCVKGQG--ALAQLDAVHNTLKSIPHYGIGYGLLRYMYAP
MMAR_1772|M.marinum_M               RFTTYYPVALTCATGQGAAALKGLDAVHDTLKSVPHYGIGYGLLRYLYAP
MUL_2015|M.ulcerans_Agy99           RFTTYYPVALTCATGQGAAALKGLDAVHDTLKSVPHYGIGYGLLRYLYAP
Mflv_3390|M.gilvum_PYR-GCK          SFAALHPVVLT-ASGQ--TASAALAEVRQTLDAVPHYGIGYGLLRYLYAP
Mvan_3123|M.vanbaalenii_PYR-1       WFTTIHPVVLT-AARQG-SATQALGDVRETLKAVPHYGIGYGLLRYLYAP
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      MQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAFDWAQLKPG
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            TGRVLGAQRTPDIHFRYAGVIPELPSG---DAPVQFDSDMTLPVREPIPG
Rv2935|M.tuberculosis_H37Rv         TGRVLGAQRTPDIHFRYAGVIPELPSG---DAPVQFDSDMTLPVREPIPG
MLBr_02353|M.leprae_Br4923          TGRVFSAQRTPDIHFRYVGVVPEPPSV---DATVQFDSDMTIPVQEPVPG
MMAR_1772|M.marinum_M               TGRVLGAQRTPDIHFRYAGTIPELPPV---DAPVQFDSDLAMPVREPLPG
MUL_2015|M.ulcerans_Agy99           TGRVLGAQRTPDIHFRYAGTIPELPPV---DAPVQFDSDLAMPVREPLPG
Mflv_3390|M.gilvum_PYR-GCK          TARLLGDGRPADILFSHVGTIPDAPADQPDDAPVRFDPDTAMPIRDALPG
Mvan_3123|M.vanbaalenii_PYR-1       TARVLGASRPADILFSHIGTIPEVPAEQPDDAPVRFDADTAMPIRDALPG
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      DKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLGVKYVYDS
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            MGHAIELRVYRFGGSLHLDWWYDTRRIPAATAEALERTFPLALSALIQEA
Rv2935|M.tuberculosis_H37Rv         MGHAIELRVYRFGGSLHLDWWYDTRRIPAATAEALERTFPLALSALIQEA
MLBr_02353|M.leprae_Br4923          MGHAIELRTYRFGGSLHLDWWYDIRRIPQVTAEALAQSFPVTLSKLIQEG
MMAR_1772|M.marinum_M               LGHAVEIRAYRSGSSLHVDWWYDTRRITAETATALARSFPTALSELIQES
MUL_2015|M.ulcerans_Agy99           LGHAVEIRAYRSGSSLHVDWWYDTRRITAETATALARSFPTALSELIQES
Mflv_3390|M.gilvum_PYR-GCK          LGHALEVRIYRTGGELHLDWWYDIRRLGPTDVESFSRQYSAAVLDISREA
Mvan_3123|M.vanbaalenii_PYR-1       LGHAVELRVYRAAGVLHLDWWYDNRRLGPTDVESFARQYSEALLDVTRDA
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      RTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKR
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            IAAEHTEHDDSEIVGEPEAGALVDLSSMDAG-------------------
Rv2935|M.tuberculosis_H37Rv         IAAEHTEHDDSEIVGEPEAGALVDLSSMDAG-------------------
MLBr_02353|M.leprae_Br4923          IATQKDAHDESEMAGAPQAGVLVDLSTLDAG-------------------
MMAR_1772|M.marinum_M               IAAEQEERDEDEKVGVIEAGALVDLSSLDAG-------------------
MUL_2015|M.ulcerans_Agy99           IAAEQEERDEDEKVGVIEAGALVDLPSLDAG-------------------
Mflv_3390|M.gilvum_PYR-GCK          LAEEDTDAAGDELA-------LVDLS------------------------
Mvan_3123|M.vanbaalenii_PYR-1       LAEEDTDAAGDELA-------LVDLS------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      DIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWT
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      PLPAEIYPITEARSAFRRMQQARHIGKIVLQVPKPLQPQQDRSYLITGGL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      GAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYA
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      ADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      APKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATANAMLDGL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      VAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHA
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      LAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSE
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      LLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTDSLM
TH_4458|M.thermoresistible__bu      --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

MAV_3107|M.avium_104                -------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      AIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA
TH_4458|M.thermoresistible__bu      -------------------------------------------------
Mb2960|M.bovis_AF2122/97            -------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         -------------------------------------------------
MLBr_02353|M.leprae_Br4923          -------------------------------------------------
MMAR_1772|M.marinum_M               -------------------------------------------------
MUL_2015|M.ulcerans_Agy99           -------------------------------------------------
Mflv_3390|M.gilvum_PYR-GCK          -------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       -------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      -------------------------------------------------