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EAESPCAASDLAVARRELLSGNHRELDPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRE LLPYSDLDVLLLHDGKPADILRPVADRLWYPLWDANIRLDHSVRTVSEALTIANSDLMAALGMLEARHIA GDQQLSFALIDGVRRQWRNGIRSRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQ LIDRHGIGHTDLPAGSLDGAYRTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSAG RTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARDAEPEHDPGLVLRVAAASAD TGLPIGAATLSRLAASVPDLPTPWPQEALDDLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPP RDVAHKWTVDRHVVETAVHAAPLATRVARPDLLALGALLHDIGKGRGTDHSVLGAELVIPVCTRLGLSPP DVRTLSKLVRHHLLLPITATRRDLNDPKTIEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASL VDDLVRRCRMVMAGESLPQAEPTAPHYLSLAADHGVHVEISPRDGERIDAVIVAPDERGLVSKAAAVLAL NSLRVHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSDAASLVSARAG DVQAGVPVTRTAAPPRILWLDTAAPAKLILEVRAMDRAGLLALLAGALEGAGAGIVWAKVNTFGSTAADV FCVTVPAELDARAAVEQHLLEVLGASVDVVVDEPVGD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2918c | glnD | - | 100% (808) | PII uridylyl-transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2942c | glnD | 0.0 | 99.75% (808) | PII uridylyl-transferase |
| M. gilvum PYR-GCK | Mflv_4183 | - | 0.0 | 62.81% (796) | PII uridylyl-transferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3238c | - | 0.0 | 61.74% (792) | PII uridylyl-transferase |
| M. marinum M | MMAR_1789 | glnD | 0.0 | 77.71% (812) | uridylyltransferase GlnD |
| M. avium 104 | MAV_3773 | glnD | 0.0 | 75.90% (805) | PII uridylyl-transferase |
| M. smegmatis MC2 155 | MSMEG_2427 | glnD | 0.0 | 65.25% (774) | PII uridylyl-transferase |
| M. thermoresistible (build 8) | TH_1479 | glnD | 0.0 | 66.19% (695) | PROBABLE |
| M. ulcerans Agy99 | MUL_1336 | glnE | 9e-05 | 25.71% (315) | glutamate-ammonia-ligase adenylyltransferase GlnE |
| M. vanbaalenii PYR-1 | Mvan_2180 | - | 0.0 | 63.67% (790) | PII uridylyl-transferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2918c|M.tuberculosis_H37Rv ------MEAE-----------------SPCAASDLAVARRELLSGNHREL
Mb2942c|M.bovis_AF2122/97 ------MEAE-----------------SPCAASDLAVARRELLSGNHREL
MMAR_1789|M.marinum_M ------MEPG-----------------SVRAASDLAAARRQLLSDDHRDM
MAV_3773|M.avium_104 ------MTPTGP---------DPSGHQNACGAVDLAASRRQLLSEGG-KL
Mflv_4183|M.gilvum_PYR-GCK ------MKDSTSKPAAGASRWERPAAVSSRPATDLVAAAEQLLAGGARPL
Mvan_2180|M.vanbaalenii_PYR-1 ------MKEQKSQPAAGAPRWERPAAGSLRPATDLVAAADQLLSG-SRQL
MSMEG_2427|M.smegmatis_MC2_155 ------MAEHKTQSAG--ASHKGAPAGSSRPANDLAAAVSQLLTGGPRQL
TH_1479|M.thermoresistible__bu ------MTEQTPGPASGSFPAKDPEAVCSKPARDLVAATERLLAGGARQL
MAB_3238c|M.abscessus_ATCC_199 ----------------------------MGAATDLVAARAQLLGD-SGRL
MUL_1336|M.ulcerans_Agy99 MNVTKPATQRPKLPSVGRLGLVDALAGAHLAELGWTEHDDQAHVDLLWSL
. . . :
Rv2918c|M.tuberculosis_H37Rv DPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSD
Mb2942c|M.bovis_AF2122/97 DPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSD
MMAR_1789|M.marinum_M DPAELRQAWLDLHESWLIAKAAQIGIADDSGYAIVGVGGLGRRELLPYSD
MAV_3773|M.avium_104 HAAELRHAWLDLHESWLAAKAAQIGIADDSGFALVGIGGLGRHELLPYSD
Mflv_4183|M.gilvum_PYR-GCK DSAALRDALLDLHDFWLTTKATEIGITATSGFAIVATGGLGRGELLPYSD
Mvan_2180|M.vanbaalenii_PYR-1 DAAALRDALLDLYDFWLTTKASEIGITATSGFAIVATGGLGRGELLPYSD
MSMEG_2427|M.smegmatis_MC2_155 DSAALRDALLDLYEFWLTTKATELGITADSGFAIVATGGLGRGEMLPYSD
TH_1479|M.thermoresistible__bu DAASLRYALLDLHELWLNTKAAEIGITPVSGFSIVATGGLGRGELVPHSD
MAB_3238c|M.abscessus_ATCC_199 NAAAIREAMTDLNELWLTTKAAEVGITDSSGFAIVALGGLGRREMLPYSD
MUL_1336|M.ulcerans_Agy99 SRAPDADAALKVLVRLAENPDTGWDELNAALLNERSLRGRLFAVLGSSLS
. : .: . : . * : . .
Rv2918c|M.tuberculosis_H37Rv LDVLLLHDG-----KPADILRPVADRLWYPLWDANIRLDHSVRTVSEALT
Mb2942c|M.bovis_AF2122/97 LDVLLLHDG-----KPADILRPVADRLWYPLWDANIRLDHSVRTVSEALT
MMAR_1789|M.marinum_M LDLVLVHDG-----KPVEELGDVADALWYPLWDANIRLDHSVRTVSDALG
MAV_3773|M.avium_104 LDLMLLHDN-----KSDEVLQRVADALWYPLWDANVRLDHSVRTVSGALG
Mflv_4183|M.gilvum_PYR-GCK LDLMLLHDN-----MPAEIVGEVAELLWYPLWDANIRLDHSVRTVPEALR
Mvan_2180|M.vanbaalenii_PYR-1 LDLMLLHDN-----MPPEIVSEVAELLWYPLWDANIRLDHSVRTVPEALR
MSMEG_2427|M.smegmatis_MC2_155 LDLMLLHDN-----MPVDVVTEVAEKLWYPLWDANIRLDHSVRTVPEALK
TH_1479|M.thermoresistible__bu LDLMLLHDG-----MPTELVGRIAEQLWYPLWDANIRIDHSVRTVAEALA
MAB_3238c|M.abscessus_ATCC_199 LDLVLLHDEN----IAPETLSEVADGLWYPLWDANIRLDHSVRTVADTLH
MUL_1336|M.ulcerans_Agy99 LGDHLVANPQSWKLLRGKVALPSHAALLESFVDLAEEVAAAPASAVHRLR
*. *: : . * .: * .: : :. *
Rv2918c|M.tuberculosis_H37Rv IANSDLMAALGMLEARHIAGDQ-QLSFALIDGVRRQWRNGIRSRMGELVE
Mb2942c|M.bovis_AF2122/97 IANSDLMAALGMLEARHIAGDQ-QLSFALIDGVRRQWRNGIRSRMGELVE
MMAR_1789|M.marinum_M VAGADMAAALGMLEARHIVGDQ-QLSASLIDGVRRQWRSGIRSRMNELVD
MAV_3773|M.avium_104 VANGDMIAALGMLDARHVAGDA-RLSDELIAGARRQWRSAIRSRMDELVE
Mflv_4183|M.gilvum_PYR-GCK VAGEDISAGLAMLEARHIAGDA-DLSSLLIGGARRQWRTGIAPRFEELVE
Mvan_2180|M.vanbaalenii_PYR-1 VAGTDISAGLAMLEARHIAGDG-DLSSLLIGGARRQWRTGIASRFDELVE
MSMEG_2427|M.smegmatis_MC2_155 VAGEDISVGLAMLDVRHIAGDA-DLSSLLVGGARRQWRIGIASRFEELVE
TH_1479|M.thermoresistible__bu VADADIAAGLAMLEARHIAGDA-DLSALVIDGARRHWRTTIASRFDELID
MAB_3238c|M.abscessus_ATCC_199 VAGQEMSAALALLDARHIAGDA-QLSSLMIGGVRQQWRSQIRTRLDELVE
MUL_1336|M.ulcerans_Agy99 ALHRDHVLVLAGLDLAATVEDEPVLSFTVVAAHLADIADAALAAALRLAE
: *. *: . * ** :: . . . .* :
Rv2918c|M.tuberculosis_H37Rv MTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHT
Mb2942c|M.bovis_AF2122/97 MTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHT
MMAR_1789|M.marinum_M MTHDRWLRCGRVANRAEPDLKSGRGGLRDVQLLDALAIAQLIDRHGLVTP
MAV_3773|M.avium_104 MTQARWDRCGRIAQRAEPDLKSGRGGLRDVQLLDALGVAQLIDRHGMARP
Mflv_4183|M.gilvum_PYR-GCK HARARWQRSGEIAHRAEPDLKCGRGGLRDVQLLNALAIAQLADVYPSRSL
Mvan_2180|M.vanbaalenii_PYR-1 HTRARWQRSGEIAHRAEPDLKCGRGGLRDVQLLNALAIAQLADVYPSRSL
MSMEG_2427|M.smegmatis_MC2_155 HAQARWQRSGQIAHRAEPDLKSGRGGLRDVQLLNALAIAQLADVYPSRAL
TH_1479|M.thermoresistible__bu HTRARWERSGQIAHRAEPDLKCGRGGLRDVQLLNALAIAQLADGYPSSSL
MAB_3238c|M.abscessus_ATCC_199 YTQARWRRSGEIAHRAEPDLKSGRGGLRDVQLLRALAIAQLTDSGLAKSF
MUL_1336|M.ulcerans_Agy99 KTVCRDRTPPRLAVIAVG--KCGARELNYVSDVDVIFVAERADPISIRVA
: * .:* * * * *. *. : .: :*: *
Rv2918c|M.tuberculosis_H37Rv DLPAGSLDGAYRTLLD-----------VRTELHRVSGRGRDHLLAQFADE
Mb2942c|M.bovis_AF2122/97 DRPAGSLDGAYRTLLD-----------VRTELHRVSGRGRDHLLAQFADE
MMAR_1789|M.marinum_M DMPVGSLDAAYLTLLN-----------VRTELHRVSGRGRDLLLAQHADD
MAV_3773|M.avium_104 ESPGGSLDDAHLTLLD-----------VRTELHRVSGRGLDQLLAQYGDE
Mflv_4183|M.gilvum_PYR-GCK ASPTETLGEANLALLN-----------VRTELHRVAGRGRELLLAQHADE
Mvan_2180|M.vanbaalenii_PYR-1 ASPTETLGEAHLSLLN-----------VRTELHRVAGRGRELLLAQHADE
MSMEG_2427|M.smegmatis_MC2_155 ASPTGTLGGAHLALLN-----------VRTELHRVSGRGRELLLAQHADE
TH_1479|M.thermoresistible__bu ASPTGTLGDAHLALLD-----------VRTELHRIAGRGRDLLQAQYADE
MAB_3238c|M.abscessus_ATCC_199 DG-------AHSVILD-----------VRTELHRVAGRERDQLLAQFADE
MUL_1336|M.ulcerans_Agy99 GEMMRVASSTFFEVDAGLRPEGRSGELVRTVESHIAYYQRWAKTWEFQAL
: : *** ::: :.
Rv2918c|M.tuberculosis_H37Rv ISAALGFGDRFDLARTLSSAGRTIGYHAEAGLRTAANALPRRGISALVRR
Mb2942c|M.bovis_AF2122/97 ISAALGFGDRFDLARTLSSAGRTIGYHAEAGLRTAANALPRRGISALVRR
MMAR_1789|M.marinum_M ISAALHFGDRFDLARMLSSAGRTIAYHAESGLRTACNALPRRGISALRRR
MAV_3773|M.avium_104 LSAALHIGDRFDLARKLSDASRTIAYHAETGLRTAENALPRRGVSALVRR
Mflv_4183|M.gilvum_PYR-GCK IGASLRIGDRFDLARTLSDAARTVSYYVDAGIRTAANSLPRRGLAAL-RR
Mvan_2180|M.vanbaalenii_PYR-1 IGAALHIGDRFDLARMLSDAARTVSYYVDAGIRTAANALPRRGLAVL-RR
MSMEG_2427|M.smegmatis_MC2_155 IGAALRIGDRFDLARMLSDAARTVSYYVDSGIRTAANALPRRGFAAL-RR
TH_1479|M.thermoresistible__bu IAAALRIGDRFDLARLLSDAARTVSYYVDSGLRTAANALPRRGFAAL-RR
MAB_3238c|M.abscessus_ATCC_199 IGAALRIGDRFDLARMLSDAARTISYSVDVGLRAAANSIPRRGISAL-RR
MUL_1336|M.ulcerans_Agy99 LKARAAVGDAELGQRYLAALMPMVWTACERDDFVAEVQAMRRRVEQLVPA
: * .** * *: : : . .* ** . *
Rv2918c|M.tuberculosis_H37Rv PKR-RPLDEG-----VVEYAGEIVLARDAEPEHDPGLVLRVAAASADTG-
Mb2942c|M.bovis_AF2122/97 PKR-RPLDEG-----VVEYAGEIVLARDAEPEHDPGLVLRVAAASADTG-
MMAR_1789|M.marinum_M PKR-RPLDEG-----VVECANEIVLARDAQPEQDAGLVLRVAAAAAHAG-
MAV_3773|M.avium_104 PKR-RPLDEG-----VVEYAGEIVLARDARPDTDVGLVLRVAAASASTG-
Mflv_4183|M.gilvum_PYR-GCK PVR-RPLDEG-----VIEFAGEVILARDARPERDPGLILRVAAASATTG-
Mvan_2180|M.vanbaalenii_PYR-1 PVR-RPLDEG-----VIEFNGEVILARDARPERDPGLILRVAAASATTG-
MSMEG_2427|M.smegmatis_MC2_155 PVR-RPLDEG-----VIEFAGEVILARDARPERDPGLVLRVAAASATTG-
TH_1479|M.thermoresistible__bu PLR-RPLDEG-----VVEYAGEVILARDARPARDPGLILRVAAASATTG-
MAB_3238c|M.abscessus_ATCC_199 TVR-RPIDEG-----VVEHAGEVVLARDARPERDPSLILRVAAASATTG-
MUL_1336|M.ulcerans_Agy99 DIRGRELKLGTGGLRDVEFVAQLLQLVHGRSDESLHVASTVDALSALGEG
* * :. * :* ::: .... . : * * :*
Rv2918c|M.tuberculosis_H37Rv ---------LPIGAATLSRLAASVPDLP----TPWPQEALDDLLVVLSAG
Mb2942c|M.bovis_AF2122/97 ---------LPIGAATLSRLAASVPDLP----TPWPQEALDDLLVVLSAG
MMAR_1789|M.marinum_M ---------LPIGAATLRRLADSAAELP----TPWPREVLDDLLVVLLAG
MAV_3773|M.avium_104 ---------LPIGAATLSRLAAAAPEMP----EPWPREALDDLLVLLSAG
Mflv_4183|M.gilvum_PYR-GCK ---------LPIAGSTLSRLVEAAPELR----TPWPRQALKDLLVMLAAG
Mvan_2180|M.vanbaalenii_PYR-1 ---------LPMAASTLSRLVEAAPELR----TPWPGQALKDLLVMLAAG
MSMEG_2427|M.smegmatis_MC2_155 ---------LPIAVSTLSRLAETAPELR----TPWPSQALKDLLVLLAAG
TH_1479|M.thermoresistible__bu ---------LPIAASTLSRLAATAPELR----APWPRPALNDLLVLLGAG
MAB_3238c|M.abscessus_ATCC_199 ---------LPIAASTLARLAESAPELR----TPWPREALKDLLVLLESG
MUL_1336|M.ulcerans_Agy99 GYIGREDAANMIASYEFLRLLEHRLQLQRLKRTHLLPEFDDEEAVRWLAR
:. : ** :: .: * :
Rv2918c|M.tuberculosis_H37Rv PTTVATIEALDRTGLWGRLLPEWEP-IRDLPPRDVAHKWTVDRHVVETAV
Mb2942c|M.bovis_AF2122/97 PTTVATIEALDRTGLWGRLLPEWEP-IRDLPPRDVAHKWTVDRHVVETAV
MMAR_1789|M.marinum_M PTAVVTIEALDRTGLWGRLLPEWGA-IRDLPPRDVAHKWTVDRHLIETAV
MAV_3773|M.avium_104 PTTVATIEALDRTGLWGRLLPEWDA-IRDLPPRDVAHKWTVDRHVIETTV
Mflv_4183|M.gilvum_PYR-GCK PSAVGTIEALDRTGLWGRLFPEWGA-VRDLPPRDVVHIWTVDRHLVETVS
Mvan_2180|M.vanbaalenii_PYR-1 PSAVATIEALDRTGLWGRLFPEWGA-VRDLPPRDVVHIWTVDRHLVETVS
MSMEG_2427|M.smegmatis_MC2_155 PAAVATIEALDRTGLWGRLFPEWGA-VRDLPPRDVVHIWTVDRHLVETVS
TH_1479|M.thermoresistible__bu PAAVGTIEALDRTGLWGRLFPEWGA-VRDLPPRDIVHVWTVDRHLTETVA
MAB_3238c|M.abscessus_ATCC_199 RPALATIEALDRTGLWGRLFPEWGP-VRDLPPRDIVHIWTVDRHLVETVV
MUL_1336|M.ulcerans_Agy99 AAHIRPDGRHDAAGMLREELKHQNVRVSRLHAKLFYQPLLESIAPAGLEI
. : . * :*: . : . : * .: . : .
Rv2918c|M.tuberculosis_H37Rv HAAPLATRVARPDLLALG------ALLHDIGKG-RGTDHSVLGAELVIPV
Mb2942c|M.bovis_AF2122/97 HAAPLATRVARPDLLALG------ALLHDIGKG-RGTDHSVLGAELVIPV
MMAR_1789|M.marinum_M QAAPLTTQVARPDLLALG------ALLHDIGKG-RGADHSVLGAEMVVAI
MAV_3773|M.avium_104 NAAPLATRVARPDLLALG------ALLHDIGKG-RGVDHSVLGAGLALEI
Mflv_4183|M.gilvum_PYR-GCK RASAFTTRVSRPDLLLLG------ALVHDIGKG-RGGDHSVIGAELAHQI
Mvan_2180|M.vanbaalenii_PYR-1 RASAFTTRVSRPDLLILG------ALVHDIGKG-RGGDHSVIGAELADQI
MSMEG_2427|M.smegmatis_MC2_155 RASAFTTRVSRPDLLLLG------ALCHDIGKG-RGGDHSVIGAELATQI
TH_1479|M.thermoresistible__bu QASALTTRVSRPDLLLLG------ALLHDIGKG-RGGDHSVIGAELAAQI
MAB_3238c|M.abscessus_ATCC_199 QASAFTTRVSRPDLLVLG------ALVHDIGKG-RGGDHSVVGADLAVQI
MUL_1336|M.ulcerans_Agy99 AGRGMTSEAAERQLAALGYEGPQTALKHMAALVNHSGRRARVQSVLLPRL
. :::..:. :* ** ** * . :. :: : : : :
Rv2918c|M.tuberculosis_H37Rv CTRLGLSP-PDVRTLSKLVRHHLLLPITATRRDLND-PKTIEAVSEALGG
Mb2942c|M.bovis_AF2122/97 CTRLGLSP-PDVWTLSKLVRHHLLLPITATRRDLND-PKTIEAVSEALGG
MMAR_1789|M.marinum_M GQRLGISA-PDIDLLSKLVRHHLLLPVVATRSDLND-PSTITRVSEALGG
MAV_3773|M.avium_104 GPRLGMAP-ADVELLAQLVRHHLLLPVAATRSDLND-PKTIERVSKTLGE
Mflv_4183|M.gilvum_PYR-GCK GSRLGLWP-SDIKILAQVVRYHLLLPHTATRRDLQD-AATISAVVDALDG
Mvan_2180|M.vanbaalenii_PYR-1 GSRLGLWP-SDIRVLSTLVRHHLLLPHTATRRDLQD-PATIAAVVDALDG
MSMEG_2427|M.smegmatis_MC2_155 GTRLGLWP-SDIDVLSKLVRYHLLLPETATRRDLQD-PKTIAAVVDALGG
TH_1479|M.thermoresistible__bu GARLGLWP-SDIDILVKLVRHHLLLVRTATRRDLDD-PRTIESVVDALGP
MAB_3238c|M.abscessus_ATCC_199 GTRLGLWP-SDVELLSKIVRYHLLLPNTATRRDLAD-PETIDGVVNTLGG
MUL_1336|M.ulcerans_Agy99 LDWLSYAPDPDGGLLAYRRLSEALAPQSWYLSTLRDKPTVGRRLMHVLGT
*. . .* * . * * * . . : ..*.
Rv2918c|M.tuberculosis_H37Rv DPQLLEVLHALSEADS----KATGPGVWSDWKASLVDDLVR-------RC
Mb2942c|M.bovis_AF2122/97 DPQLLEVLHALSEADS----KATGPGVWSDWKASLVDDLVR-------RC
MMAR_1789|M.marinum_M DPQLLEVLRALTEADS----KATGPGVWSDWKASLVDDLVS-------RC
MAV_3773|M.avium_104 DPLLLEVLHALTEADS----KATGPGVWSDWKASLIDDLVR-------RC
Mflv_4183|M.gilvum_PYR-GCK DPAVLELLHVLAEADS----LATGPGVWGDWKASLLGELVR-------RC
Mvan_2180|M.vanbaalenii_PYR-1 DLVVLELLHVLAEADS----LATGPGVWGDWKASLIGELVR-------RC
MSMEG_2427|M.smegmatis_MC2_155 DMVVLELLDVLAEADS----LATGPGVWGDWKASLIGDLVR-------RC
TH_1479|M.thermoresistible__bu DPVLLDLLHALVEADS----LATGPGVWGEWKAALIGDLVR-------RC
MAB_3238c|M.abscessus_ATCC_199 DLLLLELLQQLAEADS----LATGPGVWGDWKASLIGELVR-------KC
MUL_1336|M.ulcerans_Agy99 SAFVPDLLMRAPEVIQNYGDSRTGPKLLETEPAAVARALIASAGRYSDPL
. : ::* *. . *** : *:: *:
Rv2918c|M.tuberculosis_H37Rv RMVMAGESLPQAEPTAP---HYLSLAADHGVHVEIS--------------
Mb2942c|M.bovis_AF2122/97 RMVMAGESLPQAEPTAP---HYLSLAADHGVHVEIS--------------
MMAR_1789|M.marinum_M RLAMAGEPLPRADPEAP---HYVSLSADHGVHVEIA--------------
MAV_3773|M.avium_104 RMVMAGEPLPKVEPAAP---QYLSLAADRGVHVQIK--------------
Mflv_4183|M.gilvum_PYR-GCK RMVMAGEPLPHPDPVDP---RFISLAGQVGVHVELT--------------
Mvan_2180|M.vanbaalenii_PYR-1 RLVMAGEPLPHPDPVDP---RFVALAGDGGVHVELT--------------
MSMEG_2427|M.smegmatis_MC2_155 RLVMAGEPLPHPDPIDP---RFLEIAADVGVHVELT--------------
TH_1479|M.thermoresistible__bu RLVMAGEPLPHPDPIDP---QHLSLAARGGVHVDLV--------------
MAB_3238c|M.abscessus_ATCC_199 RLVMRGEQLPEPDPIDP---ELLSLAADGGVQVRLV--------------
MUL_1336|M.ulcerans_Agy99 RAIAAARTLRRRELARIGSADLLGLLEVTEVCRALTSVWVAVLQSALEAM
* .. * . : : : * :
Rv2918c|M.tuberculosis_H37Rv -----PRDGERI-DAVIVAPDERG----LVSKAAAVLALNSLRVHSASVN
Mb2942c|M.bovis_AF2122/97 -----PRDGERI-DAVIVAPDERG----LVSKAAAVLALNSLRVHSASVN
MMAR_1789|M.marinum_M -----PGESARMYQVVMAAPNKPG----LVSKAAAVLALNSLGVHSAWVN
MAV_3773|M.avium_104 -----PGGGERL-DVVMAAPDQRG----LVSKAAAVLALNSLRIHSASAS
Mflv_4183|M.gilvum_PYR-GCK -----PTDTPHIYQVTMIAPDSRG----VLSKAAGVMALNSLRVHSASVN
Mvan_2180|M.vanbaalenii_PYR-1 -----PAEHSHIYNVTMIAPDSRG----LLSKTAGVLALNSLRVHSASVN
MSMEG_2427|M.smegmatis_MC2_155 -----PGDGQHIFNVTMIAPDRRG----LLSKAAGVLALNSLRVHSASVN
TH_1479|M.thermoresistible__bu -----PGDGPHIYQVTLVAPDRRG----LLSKAAGVLALNSLRVHSASVN
MAB_3238c|M.abscessus_ATCC_199 -----PAGSPHMYIVSLIAPDQRG----LLSKAAGVLSLNSLRVFSASVA
MUL_1336|M.ulcerans_Agy99 IRANTPEGGRPLARIAVIGMGRLGGSELSYGSDADVMYVCEPASGVTDAQ
* : : . . * .. * *: : . : .
Rv2918c|M.tuberculosis_H37Rv VHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSD-
Mb2942c|M.bovis_AF2122/97 VHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSD-
MMAR_1789|M.marinum_M SHEGVAITQFVVSPLFGTPAAADLLRQQFVGALSGDIDALAMVEKRDSE-
MAV_3773|M.avium_104 THEGFAVVEFVVSPLFGSPPEAGLLRQQFTGALGGDVDVLGTLEKRDSD-
Mflv_4183|M.gilvum_PYR-GCK GHEGSAINSFVVSPRFGTPPAAELLRQQLILAIDGELDVMGALEKKE---
Mvan_2180|M.vanbaalenii_PYR-1 GHEGAAINTFVVSPRFGSPPAAELLRQQLILAIDGELDVMGALEKKE---
MSMEG_2427|M.smegmatis_MC2_155 SHEGSAINTFVVSPHFGSPPAADLLRQQFVLALDGDLDVIGSLERRERE-
TH_1479|M.thermoresistible__bu SHHGSAINTFVVSPHFGAPPAANLLRQQLILALDGDLDVLAALERRDHDG
MAB_3238c|M.abscessus_ATCC_199 SHAGSAINTFEVSPRFGSPPAAGLLRQQLISAIDGDTDIIAALDERERE-
MUL_1336|M.ulcerans_Agy99 GVKWSTAVAEQVRAKLGTPSVDPPLEVDANLRPEGRNGPLVRTLASYGAY
: * . :*:*. :. : * . :
Rv2918c|M.tuberculosis_H37Rv -----------AASLVSARAGDVQAG------------------------
Mb2942c|M.bovis_AF2122/97 -----------AASLVSARAGDVQAG------------------------
MMAR_1789|M.marinum_M -----------ATSNASQRAGEVVAG------------------------
MAV_3773|M.avium_104 -----------AVGAATRRAGEVQVG------------------------
Mflv_4183|M.gilvum_PYR-GCK -----------AESVATGRAGEVRAA------------------------
Mvan_2180|M.vanbaalenii_PYR-1 -----------AESTATGRAGEIRAA------------------------
MSMEG_2427|M.smegmatis_MC2_155 -----------AAQYPTTRAGEILAA------------------------
TH_1479|M.thermoresistible__bu --APGSHRPGEPAXXXVGVAAESIAAGLTAFEVGRHRAELIATAGGISYV
MAB_3238c|M.abscessus_ATCC_199 -----------SAQFATGVVGDAAPA------------------------
MUL_1336|M.ulcerans_Agy99 YAQWAQAWEIQALLRAHAVAGDAALG------------------------
. ..: .
Rv2918c|M.tuberculosis_H37Rv ---------VPVTRTAAPP---------RILWLDT-----AAPAKLILEV
Mb2942c|M.bovis_AF2122/97 ---------VPVTRTAAPP---------RILWLDT-----AAPAKLILEV
MMAR_1789|M.marinum_M ---------VPVTRSTAPP---------RILWLDS-----AAPDQLVLEV
MAV_3773|M.avium_104 ---------VPVTRSTAPP---------RILWVDT-----AAADQLIVEV
Mflv_4183|M.gilvum_PYR-GCK ---------VPINAPTAPP---------KVLWHEP-----SGSGHVVAEI
Mvan_2180|M.vanbaalenii_PYR-1 ---------VPINPPTAPP---------RVLWHEG-----AGAGQVVAEI
MSMEG_2427|M.smegmatis_MC2_155 ---------VPANHVPAPP---------RLLWADG-----SNPGELIVQI
TH_1479|M.thermoresistible__bu DDSKATNPHAAAASIAAHP---------RVVWIAGGLLKGAAVDELVAEV
MAB_3238c|M.abscessus_ATCC_199 ---------VPTNYAPAPP---------RIRWFEP----AGNADQQIVEI
MUL_1336|M.ulcerans_Agy99 -----QRFLLLVDHTRYPPDGVSAEAVHEIRRIKARVESERLPRGADPNT
* .: :
Rv2918c|M.tuberculosis_H37Rv RAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST-----------
Mb2942c|M.bovis_AF2122/97 RAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST-----------
MMAR_1789|M.marinum_M RSMDRPGLLA-----LLTRALERAGADIVWAKVNTFGST-----------
MAV_3773|M.avium_104 RAMDRLGLLA-----LLTRALERAGTDIVWAKVNTFGST-----------
Mflv_4183|M.gilvum_PYR-GCK RATDRTGLLA-----VLTRVFERAGVDIAWAKVTTMGSS-----------
Mvan_2180|M.vanbaalenii_PYR-1 RATDRAGLLA-----VLTRVLERAGVDIAWAKVTTLGSS-----------
MSMEG_2427|M.smegmatis_MC2_155 RTIDRAGLLA-----RLTAVFERDGVDIAWAKVTTLGSS-----------
TH_1479|M.thermoresistible__bu ADRLAGXXLIGRDREIIAQALSRHAPEVPVVSVVTGDDSGMQATAGAPVN
MAB_3238c|M.abscessus_ATCC_199 RTSDAPGLLA-----RITATLERHGVDIAWAKVNTLGSS-----------
MUL_1336|M.ulcerans_Agy99 HTKLGRGGLADIEWTVQLLQLQNAHEIEALHNTSTLESLDAIAEAKLVAE
* :. .. * .
Rv2918c|M.tuberculosis_H37Rv ----AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVGD-
Mb2942c|M.bovis_AF2122/97 ----AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVGD-
MMAR_1789|M.marinum_M ----AADVFCVTVSAGLEEPQARAA-MEQQLSAVLGGSADVLLDEPVGD-
MAV_3773|M.avium_104 ----AADAFCVTA-GDAG---ARDA-VEQSLLTVLGGPAVEVLEEPVGD-
Mflv_4183|M.gilvum_PYR-GCK ----VIDVFGIVLPAG-EDAVRES--LEKQLLAVLPAPPQPKPVREEAS-
Mvan_2180|M.vanbaalenii_PYR-1 ----VVDAFGIVLPAD-GAAARQN--LERELFAVLPAPP-AKPAEVEAS-
MSMEG_2427|M.smegmatis_MC2_155 ----VVDAFGITTADGRTEQVRQE--LERDLYAVLPTPPPAKPAEQAS--
TH_1479|M.thermoresistible__bu AVTRVVEATEPIGPAVMTAAVAAARALASPGDTVLLAPAGASFDQFSGYA
MAB_3238c|M.abscessus_ATCC_199 ----VVDTFCLSTGPE-QAVLEAA--IASVLPAVAPQPKKAAAS------
MUL_1336|M.ulcerans_Agy99 DEVKLLRQAWLTATRARNALVLVRGKPTDQLPGPGRQLNAVAVAAGWHND
Rv2918c|M.tuberculosis_H37Rv --------------------------
Mb2942c|M.bovis_AF2122/97 --------------------------
MMAR_1789|M.marinum_M --------------------------
MAV_3773|M.avium_104 --------------------------
Mflv_4183|M.gilvum_PYR-GCK --------------------------
Mvan_2180|M.vanbaalenii_PYR-1 --------------------------
MSMEG_2427|M.smegmatis_MC2_155 --------------------------
TH_1479|M.thermoresistible__bu DRGDAFAAAVRAAIR-----------
MAB_3238c|M.abscessus_ATCC_199 --------------------------
MUL_1336|M.ulcerans_Agy99 DGGEFLDNYLRVTRRAKAVVRKVFGS