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GAATDLVAARAQLLGDSGRLNAAAIREAMTDLNELWLTTKAAEVGITDSSGFAIVALGGLGRREMLPYSD LDLVLLHDENIAPETLSEVADGLWYPLWDANIRLDHSVRTVADTLHVAGQEMSAALALLDARHIAGDAQL SSLMIGGVRQQWRSQIRTRLDELVEYTQARWRRSGEIAHRAEPDLKSGRGGLRDVQLLRALAIAQLTDSG LAKSFDGAHSVILDVRTELHRVAGRERDQLLAQFADEIGAALRIGDRFDLARMLSDAARTISYSVDVGLR AAANSIPRRGISALRRTVRRPIDEGVVEHAGEVVLARDARPERDPSLILRVAAASATTGLPIAASTLARL AESAPELRTPWPREALKDLLVLLESGRPALATIEALDRTGLWGRLFPEWGPVRDLPPRDIVHIWTVDRHL VETVVQASAFTTRVSRPDLLVLGALVHDIGKGRGGDHSVVGADLAVQIGTRLGLWPSDVELLSKIVRYHL LLPNTATRRDLADPETIDGVVNTLGGDLLLLELLQQLAEADSLATGPGVWGDWKASLIGELVRKCRLVMR GEQLPEPDPIDPELLSLAADGGVQVRLVPAGSPHMYIVSLIAPDQRGLLSKAAGVLSLNSLRVFSASVAS HAGSAINTFEVSPRFGSPPAAGLLRQQLISAIDGDTDIIAALDERERESAQFATGVVGDAAPAVPTNYAP APPRIRWFEPAGNADQQIVEIRTSDAPGLLARITATLERHGVDIAWAKVNTLGSSVVDTFCLSTGPEQAV LEAAIASVLPAVAPQPKKAAAS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_3238c | - | - | 100% (793) | PII uridylyl-transferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2942c | glnD | 0.0 | 61.74% (792) | PII uridylyl-transferase |
M. gilvum PYR-GCK | Mflv_4183 | - | 0.0 | 69.51% (797) | PII uridylyl-transferase |
M. tuberculosis H37Rv | Rv2918c | glnD | 0.0 | 61.74% (792) | PII uridylyl-transferase |
M. leprae Br4923 | MLBr_01630 | glnE | 1e-05 | 27.31% (238) | bifunctional glutamine-synthetase |
M. marinum M | MMAR_1789 | glnD | 0.0 | 61.74% (792) | uridylyltransferase GlnD |
M. avium 104 | MAV_3773 | glnD | 0.0 | 62.88% (792) | PII uridylyl-transferase |
M. smegmatis MC2 155 | MSMEG_2427 | glnD | 0.0 | 70.79% (801) | PII uridylyl-transferase |
M. thermoresistible (build 8) | TH_1479 | glnD | 0.0 | 71.87% (686) | PROBABLE |
M. ulcerans Agy99 | MUL_1336 | glnE | 3e-07 | 27.65% (264) | glutamate-ammonia-ligase adenylyltransferase GlnE |
M. vanbaalenii PYR-1 | Mvan_2180 | - | 0.0 | 70.79% (801) | PII uridylyl-transferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2942c|M.bovis_AF2122/97 -------MEAE-----------------SPCAASDLAVA---------RR Rv2918c|M.tuberculosis_H37Rv -------MEAE-----------------SPCAASDLAVA---------RR MMAR_1789|M.marinum_M -------MEPG-----------------SVRAASDLAAA---------RR MAV_3773|M.avium_104 -------MTPTGP---------DPSGHQNACGAVDLAAS---------RR Mflv_4183|M.gilvum_PYR-GCK -------MKDSTSKPAAGASRWERPAAVSSRPATDLVAA---------AE Mvan_2180|M.vanbaalenii_PYR-1 -------MKEQKSQPAAGAPRWERPAAGSLRPATDLVAA---------AD MSMEG_2427|M.smegmatis_MC2_155 -------MAEHKTQSAG--ASHKGAPAGSSRPANDLAAA---------VS TH_1479|M.thermoresistible__bu -------MTEQTPGPASGSFPAKDPEAVCSKPARDLVAA---------TE MAB_3238c|M.abscessus_ATCC_199 -----------------------------MGAATDLVAA---------RA MLBr_01630|M.leprae_Br4923 MCCTTVVVVRKPATERLKRPSVGRLGLFDPHAAENLALLGWYDYDCREHV MUL_1336|M.ulcerans_Agy99 ------MNVTKPATQRPKLPSVGRLGLVDALAGAHLAELGWTEHDDQAHV . .*. Mb2942c|M.bovis_AF2122/97 ELLSGNHRELDPVGLRQTWLDLHES----WLIDKADEIGIADASGFAIVG Rv2918c|M.tuberculosis_H37Rv ELLSGNHRELDPVGLRQTWLDLHES----WLIDKADEIGIADASGFAIVG MMAR_1789|M.marinum_M QLLSDDHRDMDPAELRQAWLDLHES----WLIAKAAQIGIADDSGYAIVG MAV_3773|M.avium_104 QLLSEGG-KLHAAELRHAWLDLHES----WLAAKAAQIGIADDSGFALVG Mflv_4183|M.gilvum_PYR-GCK QLLAGGARPLDSAALRDALLDLHDF----WLTTKATEIGITATSGFAIVA Mvan_2180|M.vanbaalenii_PYR-1 QLLSG-SRQLDAAALRDALLDLYDF----WLTTKASEIGITATSGFAIVA MSMEG_2427|M.smegmatis_MC2_155 QLLTGGPRQLDSAALRDALLDLYEF----WLTTKATELGITADSGFAIVA TH_1479|M.thermoresistible__bu RLLAGGARQLDAASLRYALLDLHEL----WLNTKAAEIGITPVSGFSIVA MAB_3238c|M.abscessus_ATCC_199 QLLGD-SGRLNAAAIREAMTDLNEL----WLTTKAAEVGITDSSGFAIVA MLBr_01630|M.leprae_Br4923 DLLWSLSRAPDADAVLRPMVRLFENPATGWDELNAALLTDRGLRGRLFAV MUL_1336|M.ulcerans_Agy99 DLLWSLSRAPDADAALKVLVRLAENPDTGWDELNAALLNERSLRGRLFAV ** .. * : * :* : * :. Mb2942c|M.bovis_AF2122/97 VGG-LGRRELLPYSDLDVLLLHDG-KPADILRPVADRLWYPLWDANIRLD Rv2918c|M.tuberculosis_H37Rv VGG-LGRRELLPYSDLDVLLLHDG-KPADILRPVADRLWYPLWDANIRLD MMAR_1789|M.marinum_M VGG-LGRRELLPYSDLDLVLVHDG-KPVEELGDVADALWYPLWDANIRLD MAV_3773|M.avium_104 IGG-LGRHELLPYSDLDLMLLHDN-KSDEVLQRVADALWYPLWDANVRLD Mflv_4183|M.gilvum_PYR-GCK TGG-LGRGELLPYSDLDLMLLHDN-MPAEIVGEVAELLWYPLWDANIRLD Mvan_2180|M.vanbaalenii_PYR-1 TGG-LGRGELLPYSDLDLMLLHDN-MPPEIVSEVAELLWYPLWDANIRLD MSMEG_2427|M.smegmatis_MC2_155 TGG-LGRGEMLPYSDLDLMLLHDN-MPVDVVTEVAEKLWYPLWDANIRLD TH_1479|M.thermoresistible__bu TGG-LGRGELVPHSDLDLMLLHDG-MPTELVGRIAEQLWYPLWDANIRID MAB_3238c|M.abscessus_ATCC_199 LGG-LGRREMLPYSDLDLVLLHDENIAPETLSEVADGLWYPLWDANIRLD MLBr_01630|M.leprae_Br4923 LGSSLALGDHLVAHPQSWKLLRGR-VSLPSRTQLHQAFDECVSNFGDDPL MUL_1336|M.ulcerans_Agy99 LGSSLSLGDHLVANPQSWKLLRGK-VALPS----HAALLESFVDLAEEVA *. *. : : . *::. . : . : Mb2942c|M.bovis_AF2122/97 HSVRTVSEALTIANSDLMAALGMLEARHIAGDQ-QLSFALIDGVRRQWRN Rv2918c|M.tuberculosis_H37Rv HSVRTVSEALTIANSDLMAALGMLEARHIAGDQ-QLSFALIDGVRRQWRN MMAR_1789|M.marinum_M HSVRTVSDALGVAGADMAAALGMLEARHIVGDQ-QLSASLIDGVRRQWRS MAV_3773|M.avium_104 HSVRTVSGALGVANGDMIAALGMLDARHVAGDA-RLSDELIAGARRQWRS Mflv_4183|M.gilvum_PYR-GCK HSVRTVPEALRVAGEDISAGLAMLEARHIAGDA-DLSSLLIGGARRQWRT Mvan_2180|M.vanbaalenii_PYR-1 HSVRTVPEALRVAGTDISAGLAMLEARHIAGDG-DLSSLLIGGARRQWRT MSMEG_2427|M.smegmatis_MC2_155 HSVRTVPEALKVAGEDISVGLAMLDVRHIAGDA-DLSSLLVGGARRQWRI TH_1479|M.thermoresistible__bu HSVRTVAEALAVADADIAAGLAMLEARHIAGDA-DLSALVIDGARRHWRT MAB_3238c|M.abscessus_ATCC_199 HSVRTVADTLHVAGQEMSAALALLDARHIAGDA-QLSSLMIGGVRQQWRS MLBr_01630|M.leprae_Br4923 DAPDSVLPRLRTLYCDQLLVLAALDLAATVEDEPVLPFTLVAAQLADIAD MUL_1336|M.ulcerans_Agy99 AAPASAVHRLRALHRDHVLVLAGLDLAATVEDEPVLSFTVVAAHLADIAD : :. * : *. *: . * *. :: . . Mb2942c|M.bovis_AF2122/97 GIRSRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALA Rv2918c|M.tuberculosis_H37Rv GIRSRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALA MMAR_1789|M.marinum_M GIRSRMNELVDMTHDRWLRCGRVANRAEPDLKSGRGGLRDVQLLDALAIA MAV_3773|M.avium_104 AIRSRMDELVEMTQARWDRCGRIAQRAEPDLKSGRGGLRDVQLLDALGVA Mflv_4183|M.gilvum_PYR-GCK GIAPRFEELVEHARARWQRSGEIAHRAEPDLKCGRGGLRDVQLLNALAIA Mvan_2180|M.vanbaalenii_PYR-1 GIASRFDELVEHTRARWQRSGEIAHRAEPDLKCGRGGLRDVQLLNALAIA MSMEG_2427|M.smegmatis_MC2_155 GIASRFEELVEHAQARWQRSGQIAHRAEPDLKSGRGGLRDVQLLNALAIA TH_1479|M.thermoresistible__bu TIASRFDELIDHTRARWERSGQIAHRAEPDLKCGRGGLRDVQLLNALAIA MAB_3238c|M.abscessus_ATCC_199 QIRTRLDELVEYTQARWRRSGEIAHRAEPDLKSGRGGLRDVQLLRALAIA MLBr_01630|M.leprae_Br4923 AAMATALRVAEKIVCGDRTPPRLAVIAMG--KWGARELNYVSDVDIIFVA MUL_1336|M.ulcerans_Agy99 AALAAALRLAEKTVCRDRTPPRLAVIAVG--KCGARELNYVSDVDVIFVA . .: : .:* * * * *. *. : : :* Mb2942c|M.bovis_AF2122/97 QLIDRHGIGHTDRPAGSLDGAYRTLLD-----------VRTELHRVSGRG Rv2918c|M.tuberculosis_H37Rv QLIDRHGIGHTDLPAGSLDGAYRTLLD-----------VRTELHRVSGRG MMAR_1789|M.marinum_M QLIDRHGLVTPDMPVGSLDAAYLTLLN-----------VRTELHRVSGRG MAV_3773|M.avium_104 QLIDRHGMARPESPGGSLDDAHLTLLD-----------VRTELHRVSGRG Mflv_4183|M.gilvum_PYR-GCK QLADVYPSRSLASPTETLGEANLALLN-----------VRTELHRVAGRG Mvan_2180|M.vanbaalenii_PYR-1 QLADVYPSRSLASPTETLGEAHLSLLN-----------VRTELHRVAGRG MSMEG_2427|M.smegmatis_MC2_155 QLADVYPSRALASPTGTLGGAHLALLN-----------VRTELHRVSGRG TH_1479|M.thermoresistible__bu QLADGYPSSSLASPTGTLGDAHLALLD-----------VRTELHRIAGRG MAB_3238c|M.abscessus_ATCC_199 QLTDSGLAKSFDG-------AHSVILD-----------VRTELHRVAGRE MLBr_01630|M.leprae_Br4923 EQADPLSTRVASEMMRVASEAFFQVDAGLRPEGRNGELVRTVESHIAYYQ MUL_1336|M.ulcerans_Agy99 ERADPISIRVAGEMMRVASSTFFEVDAGLRPEGRSGELVRTVESHIAYYQ : * : : *** ::: Mb2942c|M.bovis_AF2122/97 RDHLLAQFADEISAALGFG--------------------DRFDLARTLSS Rv2918c|M.tuberculosis_H37Rv RDHLLAQFADEISAALGFG--------------------DRFDLARTLSS MMAR_1789|M.marinum_M RDLLLAQHADDISAALHFG--------------------DRFDLARMLSS MAV_3773|M.avium_104 LDQLLAQYGDELSAALHIG--------------------DRFDLARKLSD Mflv_4183|M.gilvum_PYR-GCK RELLLAQHADEIGASLRIG--------------------DRFDLARTLSD Mvan_2180|M.vanbaalenii_PYR-1 RELLLAQHADEIGAALHIG--------------------DRFDLARMLSD MSMEG_2427|M.smegmatis_MC2_155 RELLLAQHADEIGAALRIG--------------------DRFDLARMLSD TH_1479|M.thermoresistible__bu RDLLQAQYADEIAAALRIG--------------------DRFDLARLLSD MAB_3238c|M.abscessus_ATCC_199 RDQLLAQFADEIGAALRIG--------------------DRFDLARMLSD MLBr_01630|M.leprae_Br4923 RWAKTWEFQALLKARSAVGDAELGERYLAALMPMVWAACERADFVAEVQA MUL_1336|M.ulcerans_Agy99 RWAKTWEFQALLKARAAVGDAELGQRYLAALMPMVWTACERDDFVAEVQA :. : * .* :* *:. :. Mb2942c|M.bovis_AF2122/97 AGRTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVL Rv2918c|M.tuberculosis_H37Rv AGRTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVL MMAR_1789|M.marinum_M AGRTIAYHAESGLRTACNALPRRGISALRRRPKRRPLDEGVVECANEIVL MAV_3773|M.avium_104 ASRTIAYHAETGLRTAENALPRRGVSALVRRPKRRPLDEGVVEYAGEIVL Mflv_4183|M.gilvum_PYR-GCK AARTVSYYVDAGIRTAANSLPRRGLAAL-RRPVRRPLDEGVIEFAGEVIL Mvan_2180|M.vanbaalenii_PYR-1 AARTVSYYVDAGIRTAANALPRRGLAVL-RRPVRRPLDEGVIEFNGEVIL MSMEG_2427|M.smegmatis_MC2_155 AARTVSYYVDSGIRTAANALPRRGFAAL-RRPVRRPLDEGVIEFAGEVIL TH_1479|M.thermoresistible__bu AARTVSYYVDSGLRTAANALPRRGFAAL-RRPLRRPLDEGVVEYAGEVIL MAB_3238c|M.abscessus_ATCC_199 AARTISYSVDVGLRAAANSIPRRGISAL-RRTVRRPIDEGVVEHAGEVVL MLBr_01630|M.leprae_Br4923 MRRRVEQLVPADVRGRELKLGSGGLRDVEFAVQLLQLVHGRSDESLHVVS MUL_1336|M.ulcerans_Agy99 MRRRVEQLVPADIRGRELKLGTGGLRDVEFVAQLLQLVHGRSDESLHVAS * : . .:* : *. : : .* : .: Mb2942c|M.bovis_AF2122/97 ARDAEPEH-DPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQE Rv2918c|M.tuberculosis_H37Rv ARDAEPEH-DPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQE MMAR_1789|M.marinum_M ARDAQPEQ-DAGLVLRVAAAAAHAGLPIGAATLRRLADSAAELPTPWPRE MAV_3773|M.avium_104 ARDARPDT-DVGLVLRVAAASASTGLPIGAATLSRLAAAAPEMPEPWPRE Mflv_4183|M.gilvum_PYR-GCK ARDARPER-DPGLILRVAAASATTGLPIAGSTLSRLVEAAPELRTPWPRQ Mvan_2180|M.vanbaalenii_PYR-1 ARDARPER-DPGLILRVAAASATTGLPMAASTLSRLVEAAPELRTPWPGQ MSMEG_2427|M.smegmatis_MC2_155 ARDARPER-DPGLVLRVAAASATTGLPIAVSTLSRLAETAPELRTPWPSQ TH_1479|M.thermoresistible__bu ARDARPAR-DPGLILRVAAASATTGLPIAASTLSRLAATAPELRAPWPRP MAB_3238c|M.abscessus_ATCC_199 ARDARPER-DPSLILRVAAASATTGLPIAASTLARLAESAPELRTPWPRE MLBr_01630|M.leprae_Br4923 TVDALAALGEGGYIGREDAANLTASYEFLRLLEHRLQLQRLKRTHLLPED MUL_1336|M.ulcerans_Agy99 TVDALSALGEGGYIGREDAANMIASYEFLRLLEHRLQLQRLKRTHLLPEF : ** . : . : * ** :. : ** . * Mb2942c|M.bovis_AF2122/97 ALDDLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKW Rv2918c|M.tuberculosis_H37Rv ALDDLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKW MMAR_1789|M.marinum_M VLDDLLVVLLAGPTAVVTIEALDRTGLWGRLLPEWGAIRDLPPRDVAHKW MAV_3773|M.avium_104 ALDDLLVLLSAGPTTVATIEALDRTGLWGRLLPEWDAIRDLPPRDVAHKW Mflv_4183|M.gilvum_PYR-GCK ALKDLLVMLAAGPSAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIW Mvan_2180|M.vanbaalenii_PYR-1 ALKDLLVMLAAGPSAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIW MSMEG_2427|M.smegmatis_MC2_155 ALKDLLVLLAAGPAAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIW TH_1479|M.thermoresistible__bu ALNDLLVLLGAGPAAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDIVHVW MAB_3238c|M.abscessus_ATCC_199 ALKDLLVLLESGRPALATIEALDRTGLWGRLFPEWGPVRDLPPRDIVHIW MLBr_01630|M.leprae_Br4923 GDEEAVRWLARAAHIRPDGRHDAAGVLREELKNQNLRVSQLHAKLFYQPL MUL_1336|M.ulcerans_Agy99 DDEEAVRWLARAAHIRPDGRHDAAGMLREELKHQNVRVSRLHAKLFYQPL .: : * . . * .* : : * .: . : Mb2942c|M.bovis_AF2122/97 TVDRHVVETAVHAAPLATRVARPDLLALG------ALLHDIGKG-RGTDH Rv2918c|M.tuberculosis_H37Rv TVDRHVVETAVHAAPLATRVARPDLLALG------ALLHDIGKG-RGTDH MMAR_1789|M.marinum_M TVDRHLIETAVQAAPLTTQVARPDLLALG------ALLHDIGKG-RGADH MAV_3773|M.avium_104 TVDRHVIETTVNAAPLATRVARPDLLALG------ALLHDIGKG-RGVDH Mflv_4183|M.gilvum_PYR-GCK TVDRHLVETVSRASAFTTRVSRPDLLLLG------ALVHDIGKG-RGGDH Mvan_2180|M.vanbaalenii_PYR-1 TVDRHLVETVSRASAFTTRVSRPDLLILG------ALVHDIGKG-RGGDH MSMEG_2427|M.smegmatis_MC2_155 TVDRHLVETVSRASAFTTRVSRPDLLLLG------ALCHDIGKG-RGGDH TH_1479|M.thermoresistible__bu TVDRHLTETVAQASALTTRVSRPDLLLLG------ALLHDIGKG-RGGDH MAB_3238c|M.abscessus_ATCC_199 TVDRHLVETVVQASAFTTRVSRPDLLVLG------ALVHDIGKG-RGGDH MLBr_01630|M.leprae_Br4923 LESIGPASLEIR-HGMTSEAAERQLATLGYEGSQTALKHISALVNQSGRR MUL_1336|M.ulcerans_Agy99 LESIAPAGLEIAGRGMTSEAAERQLAALGYEGPQTALKHMAALVNHSGRR . :::..:. :* ** ** * . :. : Mb2942c|M.bovis_AF2122/97 SVLGAELVIPVCTRLGLSP-PDVWTLSKLVRHHLLLPITATRRDLNDPKT Rv2918c|M.tuberculosis_H37Rv SVLGAELVIPVCTRLGLSP-PDVRTLSKLVRHHLLLPITATRRDLNDPKT MMAR_1789|M.marinum_M SVLGAEMVVAIGQRLGISA-PDIDLLSKLVRHHLLLPVVATRSDLNDPST MAV_3773|M.avium_104 SVLGAGLALEIGPRLGMAP-ADVELLAQLVRHHLLLPVAATRSDLNDPKT Mflv_4183|M.gilvum_PYR-GCK SVIGAELAHQIGSRLGLWP-SDIKILAQVVRYHLLLPHTATRRDLQDAAT Mvan_2180|M.vanbaalenii_PYR-1 SVIGAELADQIGSRLGLWP-SDIRVLSTLVRHHLLLPHTATRRDLQDPAT MSMEG_2427|M.smegmatis_MC2_155 SVIGAELATQIGTRLGLWP-SDIDVLSKLVRYHLLLPETATRRDLQDPKT TH_1479|M.thermoresistible__bu SVIGAELAAQIGARLGLWP-SDIDILVKLVRHHLLLVRTATRRDLDDPRT MAB_3238c|M.abscessus_ATCC_199 SVVGADLAVQIGTRLGLWP-SDVELLSKIVRYHLLLPNTATRRDLADPET MLBr_01630|M.leprae_Br4923 GRVQSVLLPRLLNWMSYAPDPDGGLLAYRRLSEALSAETWYLSTLRDKPA MUL_1336|M.ulcerans_Agy99 ARVQSVLLPRLLDWLSYAPDPDGGLLAYRRLSEALAPQSWYLSTLRDKPT . : : : : :. . .* * . * * * : Mb2942c|M.bovis_AF2122/97 IEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCR Rv2918c|M.tuberculosis_H37Rv IEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCR MMAR_1789|M.marinum_M ITRVSEALGGDPQLLEVLRALTEADSKATGPGVWSDWKASLVDDLVSRCR MAV_3773|M.avium_104 IERVSKTLGEDPLLLEVLHALTEADSKATGPGVWSDWKASLIDDLVRRCR Mflv_4183|M.gilvum_PYR-GCK ISAVVDALDGDPAVLELLHVLAEADSLATGPGVWGDWKASLLGELVRRCR Mvan_2180|M.vanbaalenii_PYR-1 IAAVVDALDGDLVVLELLHVLAEADSLATGPGVWGDWKASLIGELVRRCR MSMEG_2427|M.smegmatis_MC2_155 IAAVVDALGGDMVVLELLDVLAEADSLATGPGVWGDWKASLIGDLVRRCR TH_1479|M.thermoresistible__bu IESVVDALGPDPVLLDLLHALVEADSLATGPGVWGEWKAALIGDLVRRCR MAB_3238c|M.abscessus_ATCC_199 IDGVVNTLGGDLLLLELLQQLAEADSLATGPGVWGDWKASLIGELVRKCR MLBr_01630|M.leprae_Br4923 VARRLMHVLGTSVYVPDLLMRAPEVIQSYGDGLAGPKLLEAEPAMVARAL MUL_1336|M.ulcerans_Agy99 VGRRLMHVLGTSAFVPDLLMRAPEVIQNYGDSRTGPKLLETEPAAVARAL : : : * * . . * :. Mb2942c|M.bovis_AF2122/97 MVMAG------ESLPQAEPTAPHYLSLAADHGVHVEISPRDGERI-DAVI Rv2918c|M.tuberculosis_H37Rv MVMAG------ESLPQAEPTAPHYLSLAADHGVHVEISPRDGERI-DAVI MMAR_1789|M.marinum_M LAMAG------EPLPRADPEAPHYVSLSADHGVHVEIAPGESARMYQVVM MAV_3773|M.avium_104 MVMAG------EPLPKVEPAAPQYLSLAADRGVHVQIKPGGGERL-DVVM Mflv_4183|M.gilvum_PYR-GCK MVMAG------EPLPHPDPVDPRFISLAGQVGVHVELTPTDTPHIYQVTM Mvan_2180|M.vanbaalenii_PYR-1 LVMAG------EPLPHPDPVDPRFVALAGDGGVHVELTPAEHSHIYNVTM MSMEG_2427|M.smegmatis_MC2_155 LVMAG------EPLPHPDPIDPRFLEIAADVGVHVELTPGDGQHIFNVTM TH_1479|M.thermoresistible__bu LVMAG------EPLPHPDPIDPQHLSLAARGGVHVDLVPGDGPHIYQVTL MAB_3238c|M.abscessus_ATCC_199 LVMRG------EQLPEPDPIDPELLSLAADGGVQVRLVPAGSPHMYIVSL MLBr_01630|M.leprae_Br4923 ITSAGRHTDPIRAIDAARSLRRRELARVGSADLLGLLEVTEVCKALTSVW MUL_1336|M.ulcerans_Agy99 IASAGRYSDPLRAIAAARTLRRRELARIGSADLLGLLEVTEVCRALTSVW :. * . : . . : . .: : : Mb2942c|M.bovis_AF2122/97 VAPDERGLVS----------KAAAVLALNSLRVHSASVNVHQGVAITEFV Rv2918c|M.tuberculosis_H37Rv VAPDERGLVS----------KAAAVLALNSLRVHSASVNVHQGVAITEFV MMAR_1789|M.marinum_M AAPNKPGLVS----------KAAAVLALNSLGVHSAWVNSHEGVAITQFV MAV_3773|M.avium_104 AAPDQRGLVS----------KAAAVLALNSLRIHSASASTHEGFAVVEFV Mflv_4183|M.gilvum_PYR-GCK IAPDSRGVLS----------KAAGVMALNSLRVHSASVNGHEGSAINSFV Mvan_2180|M.vanbaalenii_PYR-1 IAPDSRGLLS----------KTAGVLALNSLRVHSASVNGHEGAAINTFV MSMEG_2427|M.smegmatis_MC2_155 IAPDRRGLLS----------KAAGVLALNSLRVHSASVNSHEGSAINTFV TH_1479|M.thermoresistible__bu VAPDRRGLLS----------KAAGVLALNSLRVHSASVNSHHGSAINTFV MAB_3238c|M.abscessus_ATCC_199 IAPDQRGLLS----------KAAGVLSLNSLRVFSASVASHAGSAINTFE MLBr_01630|M.leprae_Br4923 VAVLQAALDAVIRAYLPDGDKAPAAIAVIGMGRLGGAELGYGSDADVMFV MUL_1336|M.ulcerans_Agy99 VAVLQSALEAMIRANTPEGGRPLARIAVIGMGRLGGSELSYGSDADVMYV * .: : :. . ::: .: .. : . * : Mb2942c|M.bovis_AF2122/97 VSPLFGSPPAAELVR----------QQFVGALNGDVDVLGMLQKRDSD-- Rv2918c|M.tuberculosis_H37Rv VSPLFGSPPAAELVR----------QQFVGALNGDVDVLGMLQKRDSD-- MMAR_1789|M.marinum_M VSPLFGTPAAADLLR----------QQFVGALSGDIDALAMVEKRDSE-- MAV_3773|M.avium_104 VSPLFGSPPEAGLLR----------QQFTGALGGDVDVLGTLEKRDSD-- Mflv_4183|M.gilvum_PYR-GCK VSPRFGTPPAAELLR----------QQLILAIDGELDVMGALEKKE---- Mvan_2180|M.vanbaalenii_PYR-1 VSPRFGSPPAAELLR----------QQLILAIDGELDVMGALEKKE---- MSMEG_2427|M.smegmatis_MC2_155 VSPHFGSPPAADLLR----------QQFVLALDGDLDVIGSLERRERE-- TH_1479|M.thermoresistible__bu VSPHFGAPPAANLLR----------QQLILALDGDLDVLAALERRDHDG- MAB_3238c|M.abscessus_ATCC_199 VSPRFGSPPAAGLLR----------QQLISAIDGDTDIIAALDERERE-- MLBr_01630|M.leprae_Br4923 CEPAIGVEDAQALRWSGMIAERVCRLLRTPSVDPPLDVDANLRPEGRNGP MUL_1336|M.ulcerans_Agy99 CEPASGVTDAQGVKWSTAVAEQVRAKLGTPSVDPPLEVDANLRPEGRNGP .* * : ::. : . : . Mb2942c|M.bovis_AF2122/97 ----------------------AASLVSARAGDVQAG------------- Rv2918c|M.tuberculosis_H37Rv ----------------------AASLVSARAGDVQAG------------- MMAR_1789|M.marinum_M ----------------------ATSNASQRAGEVVAG------------- MAV_3773|M.avium_104 ----------------------AVGAATRRAGEVQVG------------- Mflv_4183|M.gilvum_PYR-GCK ----------------------AESVATGRAGEVRAA------------- Mvan_2180|M.vanbaalenii_PYR-1 ----------------------AESTATGRAGEIRAA------------- MSMEG_2427|M.smegmatis_MC2_155 ----------------------AAQYPTTRAGEILAA------------- TH_1479|M.thermoresistible__bu -------------APGSHRPGEPAXXXVGVAAESIAAGLTAFEVGRHRAE MAB_3238c|M.abscessus_ATCC_199 ----------------------SAQFATGVVGDAAPA------------- MLBr_01630|M.leprae_Br4923 LVRTLGAYAAYYAQWAQPWEIQALLRAHAVAGDADLG------------- MUL_1336|M.ulcerans_Agy99 LVRTLASYGAYYAQWAQAWEIQALLRAHAVAGDAALG------------- . ..: . Mb2942c|M.bovis_AF2122/97 --------------------VPVTRTAAPPRILWLDT-----AAPAKLIL Rv2918c|M.tuberculosis_H37Rv --------------------VPVTRTAAPPRILWLDT-----AAPAKLIL MMAR_1789|M.marinum_M --------------------VPVTRSTAPPRILWLDS-----AAPDQLVL MAV_3773|M.avium_104 --------------------VPVTRSTAPPRILWVDT-----AAADQLIV Mflv_4183|M.gilvum_PYR-GCK --------------------VPINAPTAPPKVLWHEP-----SGSGHVVA Mvan_2180|M.vanbaalenii_PYR-1 --------------------VPINPPTAPPRVLWHEG-----AGAGQVVA MSMEG_2427|M.smegmatis_MC2_155 --------------------VPANHVPAPPRLLWADG-----SNPGELIV TH_1479|M.thermoresistible__bu LIATAGGISYVDDSKATNPHAAAASIAAHPRVVWIAGGLLKGAAVDELVA MAB_3238c|M.abscessus_ATCC_199 --------------------VPTNYAPAPPRIRWFEP----AGNADQQIV MLBr_01630|M.leprae_Br4923 -------QRFLLMADKMRYPPDGVSAEAVREIRRMKARVEAERLPRGADP MUL_1336|M.ulcerans_Agy99 -------QRFLLLVDHTRYPPDGVSAEAVHEIRRIKARVESERLPRGADP * .: Mb2942c|M.bovis_AF2122/97 EVRAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST--------- Rv2918c|M.tuberculosis_H37Rv EVRAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST--------- MMAR_1789|M.marinum_M EVRSMDRPGLLA-----LLTRALERAGADIVWAKVNTFGST--------- MAV_3773|M.avium_104 EVRAMDRLGLLA-----LLTRALERAGTDIVWAKVNTFGST--------- Mflv_4183|M.gilvum_PYR-GCK EIRATDRTGLLA-----VLTRVFERAGVDIAWAKVTTMGSS--------- Mvan_2180|M.vanbaalenii_PYR-1 EIRATDRAGLLA-----VLTRVLERAGVDIAWAKVTTLGSS--------- MSMEG_2427|M.smegmatis_MC2_155 QIRTIDRAGLLA-----RLTAVFERDGVDIAWAKVTTLGSS--------- TH_1479|M.thermoresistible__bu EVADRLAGXXLIGRDREIIAQALSRHAPEVPVVSVVTGDDSGMQATAGAP MAB_3238c|M.abscessus_ATCC_199 EIRTSDAPGLLA-----RITATLERHGVDIAWAKVNTLGSS--------- MLBr_01630|M.leprae_Br4923 HTHTKLGRGGLADIEWTVQLMQLRHAHELPALHKTSTLESLDAIAAANLI MUL_1336|M.ulcerans_Agy99 NTHTKLGRGGLADIEWTVQLLQLQNAHEIEALHNTSTLESLDAIAEAKLV . * : .. * . Mb2942c|M.bovis_AF2122/97 ------AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVG Rv2918c|M.tuberculosis_H37Rv ------AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVG MMAR_1789|M.marinum_M ------AADVFCVTVSAGLEEPQARAA-MEQQLSAVLGGSADVLLDEPVG MAV_3773|M.avium_104 ------AADAFCVTA-GDAG---ARDA-VEQSLLTVLGGPAVEVLEEPVG Mflv_4183|M.gilvum_PYR-GCK ------VIDVFGIVLPAG-EDAVRES--LEKQLLAVLPAPPQPKPVREEA Mvan_2180|M.vanbaalenii_PYR-1 ------VVDAFGIVLPAD-GAAARQN--LERELFAVLPAPP-AKPAEVEA MSMEG_2427|M.smegmatis_MC2_155 ------VVDAFGITTADGRTEQVRQE--LERDLYAVLPTPPPAKPAEQAS TH_1479|M.thermoresistible__bu VNAVTRVVEATEPIGPAVMTAAVAAARALASPGDTVLLAPAGASFDQFSG MAB_3238c|M.abscessus_ATCC_199 ------VVDTFCLSTGPE-QAVLEAA--IASVLPAVAPQPKKAAAS---- MLBr_01630|M.leprae_Br4923 PEADVDLLRQAWLTATRARNALVLVRGKTTDQLPGPGRQLNAVAVAAGWP MUL_1336|M.ulcerans_Agy99 AEDEVKLLRQAWLTATRARNALVLVRGKPTDQLPGPGRQLNAVAVAAGWH Mb2942c|M.bovis_AF2122/97 D--------------------------- Rv2918c|M.tuberculosis_H37Rv D--------------------------- MMAR_1789|M.marinum_M D--------------------------- MAV_3773|M.avium_104 D--------------------------- Mflv_4183|M.gilvum_PYR-GCK S--------------------------- Mvan_2180|M.vanbaalenii_PYR-1 S--------------------------- MSMEG_2427|M.smegmatis_MC2_155 ---------------------------- TH_1479|M.thermoresistible__bu YADRGDAFAAAVRAAIR----------- MAB_3238c|M.abscessus_ATCC_199 ---------------------------- MLBr_01630|M.leprae_Br4923 SDDGSEFLDNYLRVTRRAKTFVRKVFGS MUL_1336|M.ulcerans_Agy99 NDDGGEFLDNYLRVTRRAKAVVRKVFGS