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M. abscessus ATCC 19977 MAB_3238c (-)

annotation: PII uridylyl-transferase
coordinates: 3272895 - 3275276
length: 793

GAATDLVAARAQLLGDSGRLNAAAIREAMTDLNELWLTTKAAEVGITDSSGFAIVALGGLGRREMLPYSD
LDLVLLHDENIAPETLSEVADGLWYPLWDANIRLDHSVRTVADTLHVAGQEMSAALALLDARHIAGDAQL
SSLMIGGVRQQWRSQIRTRLDELVEYTQARWRRSGEIAHRAEPDLKSGRGGLRDVQLLRALAIAQLTDSG
LAKSFDGAHSVILDVRTELHRVAGRERDQLLAQFADEIGAALRIGDRFDLARMLSDAARTISYSVDVGLR
AAANSIPRRGISALRRTVRRPIDEGVVEHAGEVVLARDARPERDPSLILRVAAASATTGLPIAASTLARL
AESAPELRTPWPREALKDLLVLLESGRPALATIEALDRTGLWGRLFPEWGPVRDLPPRDIVHIWTVDRHL
VETVVQASAFTTRVSRPDLLVLGALVHDIGKGRGGDHSVVGADLAVQIGTRLGLWPSDVELLSKIVRYHL
LLPNTATRRDLADPETIDGVVNTLGGDLLLLELLQQLAEADSLATGPGVWGDWKASLIGELVRKCRLVMR
GEQLPEPDPIDPELLSLAADGGVQVRLVPAGSPHMYIVSLIAPDQRGLLSKAAGVLSLNSLRVFSASVAS
HAGSAINTFEVSPRFGSPPAAGLLRQQLISAIDGDTDIIAALDERERESAQFATGVVGDAAPAVPTNYAP
APPRIRWFEPAGNADQQIVEIRTSDAPGLLARITATLERHGVDIAWAKVNTLGSSVVDTFCLSTGPEQAV
LEAAIASVLPAVAPQPKKAAAS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3238c--100% (793)PII uridylyl-transferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2942cglnD0.061.74% (792) PII uridylyl-transferase
M. gilvum PYR-GCKMflv_4183-0.069.51% (797) PII uridylyl-transferase
M. tuberculosis H37RvRv2918cglnD0.061.74% (792) PII uridylyl-transferase
M. leprae Br4923MLBr_01630glnE1e-0527.31% (238) bifunctional glutamine-synthetase
M. marinum MMMAR_1789glnD0.061.74% (792) uridylyltransferase GlnD
M. avium 104MAV_3773glnD0.062.88% (792) PII uridylyl-transferase
M. smegmatis MC2 155MSMEG_2427glnD0.070.79% (801) PII uridylyl-transferase
M. thermoresistible (build 8)TH_1479glnD0.071.87% (686) PROBABLE
M. ulcerans Agy99MUL_1336glnE3e-0727.65% (264) glutamate-ammonia-ligase adenylyltransferase GlnE
M. vanbaalenii PYR-1Mvan_2180-0.070.79% (801) PII uridylyl-transferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2942c|M.bovis_AF2122/97           -------MEAE-----------------SPCAASDLAVA---------RR
Rv2918c|M.tuberculosis_H37Rv        -------MEAE-----------------SPCAASDLAVA---------RR
MMAR_1789|M.marinum_M               -------MEPG-----------------SVRAASDLAAA---------RR
MAV_3773|M.avium_104                -------MTPTGP---------DPSGHQNACGAVDLAAS---------RR
Mflv_4183|M.gilvum_PYR-GCK          -------MKDSTSKPAAGASRWERPAAVSSRPATDLVAA---------AE
Mvan_2180|M.vanbaalenii_PYR-1       -------MKEQKSQPAAGAPRWERPAAGSLRPATDLVAA---------AD
MSMEG_2427|M.smegmatis_MC2_155      -------MAEHKTQSAG--ASHKGAPAGSSRPANDLAAA---------VS
TH_1479|M.thermoresistible__bu      -------MTEQTPGPASGSFPAKDPEAVCSKPARDLVAA---------TE
MAB_3238c|M.abscessus_ATCC_199      -----------------------------MGAATDLVAA---------RA
MLBr_01630|M.leprae_Br4923          MCCTTVVVVRKPATERLKRPSVGRLGLFDPHAAENLALLGWYDYDCREHV
MUL_1336|M.ulcerans_Agy99           ------MNVTKPATQRPKLPSVGRLGLVDALAGAHLAELGWTEHDDQAHV
                                                                    . .*.             

Mb2942c|M.bovis_AF2122/97           ELLSGNHRELDPVGLRQTWLDLHES----WLIDKADEIGIADASGFAIVG
Rv2918c|M.tuberculosis_H37Rv        ELLSGNHRELDPVGLRQTWLDLHES----WLIDKADEIGIADASGFAIVG
MMAR_1789|M.marinum_M               QLLSDDHRDMDPAELRQAWLDLHES----WLIAKAAQIGIADDSGYAIVG
MAV_3773|M.avium_104                QLLSEGG-KLHAAELRHAWLDLHES----WLAAKAAQIGIADDSGFALVG
Mflv_4183|M.gilvum_PYR-GCK          QLLAGGARPLDSAALRDALLDLHDF----WLTTKATEIGITATSGFAIVA
Mvan_2180|M.vanbaalenii_PYR-1       QLLSG-SRQLDAAALRDALLDLYDF----WLTTKASEIGITATSGFAIVA
MSMEG_2427|M.smegmatis_MC2_155      QLLTGGPRQLDSAALRDALLDLYEF----WLTTKATELGITADSGFAIVA
TH_1479|M.thermoresistible__bu      RLLAGGARQLDAASLRYALLDLHEL----WLNTKAAEIGITPVSGFSIVA
MAB_3238c|M.abscessus_ATCC_199      QLLGD-SGRLNAAAIREAMTDLNEL----WLTTKAAEVGITDSSGFAIVA
MLBr_01630|M.leprae_Br4923          DLLWSLSRAPDADAVLRPMVRLFENPATGWDELNAALLTDRGLRGRLFAV
MUL_1336|M.ulcerans_Agy99           DLLWSLSRAPDADAALKVLVRLAENPDTGWDELNAALLNERSLRGRLFAV
                                     **       ..         * :     *   :*  :      *  :. 

Mb2942c|M.bovis_AF2122/97           VGG-LGRRELLPYSDLDVLLLHDG-KPADILRPVADRLWYPLWDANIRLD
Rv2918c|M.tuberculosis_H37Rv        VGG-LGRRELLPYSDLDVLLLHDG-KPADILRPVADRLWYPLWDANIRLD
MMAR_1789|M.marinum_M               VGG-LGRRELLPYSDLDLVLVHDG-KPVEELGDVADALWYPLWDANIRLD
MAV_3773|M.avium_104                IGG-LGRHELLPYSDLDLMLLHDN-KSDEVLQRVADALWYPLWDANVRLD
Mflv_4183|M.gilvum_PYR-GCK          TGG-LGRGELLPYSDLDLMLLHDN-MPAEIVGEVAELLWYPLWDANIRLD
Mvan_2180|M.vanbaalenii_PYR-1       TGG-LGRGELLPYSDLDLMLLHDN-MPPEIVSEVAELLWYPLWDANIRLD
MSMEG_2427|M.smegmatis_MC2_155      TGG-LGRGEMLPYSDLDLMLLHDN-MPVDVVTEVAEKLWYPLWDANIRLD
TH_1479|M.thermoresistible__bu      TGG-LGRGELVPHSDLDLMLLHDG-MPTELVGRIAEQLWYPLWDANIRID
MAB_3238c|M.abscessus_ATCC_199      LGG-LGRREMLPYSDLDLVLLHDENIAPETLSEVADGLWYPLWDANIRLD
MLBr_01630|M.leprae_Br4923          LGSSLALGDHLVAHPQSWKLLRGR-VSLPSRTQLHQAFDECVSNFGDDPL
MUL_1336|M.ulcerans_Agy99           LGSSLSLGDHLVANPQSWKLLRGK-VALPS----HAALLESFVDLAEEVA
                                     *. *.  : :     .  *::.   .          :   . :      

Mb2942c|M.bovis_AF2122/97           HSVRTVSEALTIANSDLMAALGMLEARHIAGDQ-QLSFALIDGVRRQWRN
Rv2918c|M.tuberculosis_H37Rv        HSVRTVSEALTIANSDLMAALGMLEARHIAGDQ-QLSFALIDGVRRQWRN
MMAR_1789|M.marinum_M               HSVRTVSDALGVAGADMAAALGMLEARHIVGDQ-QLSASLIDGVRRQWRS
MAV_3773|M.avium_104                HSVRTVSGALGVANGDMIAALGMLDARHVAGDA-RLSDELIAGARRQWRS
Mflv_4183|M.gilvum_PYR-GCK          HSVRTVPEALRVAGEDISAGLAMLEARHIAGDA-DLSSLLIGGARRQWRT
Mvan_2180|M.vanbaalenii_PYR-1       HSVRTVPEALRVAGTDISAGLAMLEARHIAGDG-DLSSLLIGGARRQWRT
MSMEG_2427|M.smegmatis_MC2_155      HSVRTVPEALKVAGEDISVGLAMLDVRHIAGDA-DLSSLLVGGARRQWRI
TH_1479|M.thermoresistible__bu      HSVRTVAEALAVADADIAAGLAMLEARHIAGDA-DLSALVIDGARRHWRT
MAB_3238c|M.abscessus_ATCC_199      HSVRTVADTLHVAGQEMSAALALLDARHIAGDA-QLSSLMIGGVRQQWRS
MLBr_01630|M.leprae_Br4923          DAPDSVLPRLRTLYCDQLLVLAALDLAATVEDEPVLPFTLVAAQLADIAD
MUL_1336|M.ulcerans_Agy99           AAPASAVHRLRALHRDHVLVLAGLDLAATVEDEPVLSFTVVAAHLADIAD
                                     :  :.   *     :    *. *:    . *   *.  :: .   .   

Mb2942c|M.bovis_AF2122/97           GIRSRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALA
Rv2918c|M.tuberculosis_H37Rv        GIRSRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALA
MMAR_1789|M.marinum_M               GIRSRMNELVDMTHDRWLRCGRVANRAEPDLKSGRGGLRDVQLLDALAIA
MAV_3773|M.avium_104                AIRSRMDELVEMTQARWDRCGRIAQRAEPDLKSGRGGLRDVQLLDALGVA
Mflv_4183|M.gilvum_PYR-GCK          GIAPRFEELVEHARARWQRSGEIAHRAEPDLKCGRGGLRDVQLLNALAIA
Mvan_2180|M.vanbaalenii_PYR-1       GIASRFDELVEHTRARWQRSGEIAHRAEPDLKCGRGGLRDVQLLNALAIA
MSMEG_2427|M.smegmatis_MC2_155      GIASRFEELVEHAQARWQRSGQIAHRAEPDLKSGRGGLRDVQLLNALAIA
TH_1479|M.thermoresistible__bu      TIASRFDELIDHTRARWERSGQIAHRAEPDLKCGRGGLRDVQLLNALAIA
MAB_3238c|M.abscessus_ATCC_199      QIRTRLDELVEYTQARWRRSGEIAHRAEPDLKSGRGGLRDVQLLRALAIA
MLBr_01630|M.leprae_Br4923          AAMATALRVAEKIVCGDRTPPRLAVIAMG--KWGARELNYVSDVDIIFVA
MUL_1336|M.ulcerans_Agy99           AALAAALRLAEKTVCRDRTPPRLAVIAVG--KCGARELNYVSDVDVIFVA
                                       .   .: :          .:*  *    * *   *. *. :  : :*

Mb2942c|M.bovis_AF2122/97           QLIDRHGIGHTDRPAGSLDGAYRTLLD-----------VRTELHRVSGRG
Rv2918c|M.tuberculosis_H37Rv        QLIDRHGIGHTDLPAGSLDGAYRTLLD-----------VRTELHRVSGRG
MMAR_1789|M.marinum_M               QLIDRHGLVTPDMPVGSLDAAYLTLLN-----------VRTELHRVSGRG
MAV_3773|M.avium_104                QLIDRHGMARPESPGGSLDDAHLTLLD-----------VRTELHRVSGRG
Mflv_4183|M.gilvum_PYR-GCK          QLADVYPSRSLASPTETLGEANLALLN-----------VRTELHRVAGRG
Mvan_2180|M.vanbaalenii_PYR-1       QLADVYPSRSLASPTETLGEAHLSLLN-----------VRTELHRVAGRG
MSMEG_2427|M.smegmatis_MC2_155      QLADVYPSRALASPTGTLGGAHLALLN-----------VRTELHRVSGRG
TH_1479|M.thermoresistible__bu      QLADGYPSSSLASPTGTLGDAHLALLD-----------VRTELHRIAGRG
MAB_3238c|M.abscessus_ATCC_199      QLTDSGLAKSFDG-------AHSVILD-----------VRTELHRVAGRE
MLBr_01630|M.leprae_Br4923          EQADPLSTRVASEMMRVASEAFFQVDAGLRPEGRNGELVRTVESHIAYYQ
MUL_1336|M.ulcerans_Agy99           ERADPISIRVAGEMMRVASSTFFEVDAGLRPEGRSGELVRTVESHIAYYQ
                                    :  *                :   :             ***   :::   

Mb2942c|M.bovis_AF2122/97           RDHLLAQFADEISAALGFG--------------------DRFDLARTLSS
Rv2918c|M.tuberculosis_H37Rv        RDHLLAQFADEISAALGFG--------------------DRFDLARTLSS
MMAR_1789|M.marinum_M               RDLLLAQHADDISAALHFG--------------------DRFDLARMLSS
MAV_3773|M.avium_104                LDQLLAQYGDELSAALHIG--------------------DRFDLARKLSD
Mflv_4183|M.gilvum_PYR-GCK          RELLLAQHADEIGASLRIG--------------------DRFDLARTLSD
Mvan_2180|M.vanbaalenii_PYR-1       RELLLAQHADEIGAALHIG--------------------DRFDLARMLSD
MSMEG_2427|M.smegmatis_MC2_155      RELLLAQHADEIGAALRIG--------------------DRFDLARMLSD
TH_1479|M.thermoresistible__bu      RDLLQAQYADEIAAALRIG--------------------DRFDLARLLSD
MAB_3238c|M.abscessus_ATCC_199      RDQLLAQFADEIGAALRIG--------------------DRFDLARMLSD
MLBr_01630|M.leprae_Br4923          RWAKTWEFQALLKARSAVGDAELGERYLAALMPMVWAACERADFVAEVQA
MUL_1336|M.ulcerans_Agy99           RWAKTWEFQALLKARAAVGDAELGQRYLAALMPMVWTACERDDFVAEVQA
                                          :.   : *   .*                    :* *:.  :. 

Mb2942c|M.bovis_AF2122/97           AGRTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVL
Rv2918c|M.tuberculosis_H37Rv        AGRTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVL
MMAR_1789|M.marinum_M               AGRTIAYHAESGLRTACNALPRRGISALRRRPKRRPLDEGVVECANEIVL
MAV_3773|M.avium_104                ASRTIAYHAETGLRTAENALPRRGVSALVRRPKRRPLDEGVVEYAGEIVL
Mflv_4183|M.gilvum_PYR-GCK          AARTVSYYVDAGIRTAANSLPRRGLAAL-RRPVRRPLDEGVIEFAGEVIL
Mvan_2180|M.vanbaalenii_PYR-1       AARTVSYYVDAGIRTAANALPRRGLAVL-RRPVRRPLDEGVIEFNGEVIL
MSMEG_2427|M.smegmatis_MC2_155      AARTVSYYVDSGIRTAANALPRRGFAAL-RRPVRRPLDEGVIEFAGEVIL
TH_1479|M.thermoresistible__bu      AARTVSYYVDSGLRTAANALPRRGFAAL-RRPLRRPLDEGVVEYAGEVIL
MAB_3238c|M.abscessus_ATCC_199      AARTISYSVDVGLRAAANSIPRRGISAL-RRTVRRPIDEGVVEHAGEVVL
MLBr_01630|M.leprae_Br4923          MRRRVEQLVPADVRGRELKLGSGGLRDVEFAVQLLQLVHGRSDESLHVVS
MUL_1336|M.ulcerans_Agy99           MRRRVEQLVPADIRGRELKLGTGGLRDVEFVAQLLQLVHGRSDESLHVAS
                                      * :   .  .:*     :   *.  :        : .*  :   .:  

Mb2942c|M.bovis_AF2122/97           ARDAEPEH-DPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQE
Rv2918c|M.tuberculosis_H37Rv        ARDAEPEH-DPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQE
MMAR_1789|M.marinum_M               ARDAQPEQ-DAGLVLRVAAAAAHAGLPIGAATLRRLADSAAELPTPWPRE
MAV_3773|M.avium_104                ARDARPDT-DVGLVLRVAAASASTGLPIGAATLSRLAAAAPEMPEPWPRE
Mflv_4183|M.gilvum_PYR-GCK          ARDARPER-DPGLILRVAAASATTGLPIAGSTLSRLVEAAPELRTPWPRQ
Mvan_2180|M.vanbaalenii_PYR-1       ARDARPER-DPGLILRVAAASATTGLPMAASTLSRLVEAAPELRTPWPGQ
MSMEG_2427|M.smegmatis_MC2_155      ARDARPER-DPGLVLRVAAASATTGLPIAVSTLSRLAETAPELRTPWPSQ
TH_1479|M.thermoresistible__bu      ARDARPAR-DPGLILRVAAASATTGLPIAASTLSRLAATAPELRAPWPRP
MAB_3238c|M.abscessus_ATCC_199      ARDARPER-DPSLILRVAAASATTGLPIAASTLARLAESAPELRTPWPRE
MLBr_01630|M.leprae_Br4923          TVDALAALGEGGYIGREDAANLTASYEFLRLLEHRLQLQRLKRTHLLPED
MUL_1336|M.ulcerans_Agy99           TVDALSALGEGGYIGREDAANMIASYEFLRLLEHRLQLQRLKRTHLLPEF
                                    : ** .   : . : *  **   :.  :      **     .     *  

Mb2942c|M.bovis_AF2122/97           ALDDLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKW
Rv2918c|M.tuberculosis_H37Rv        ALDDLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKW
MMAR_1789|M.marinum_M               VLDDLLVVLLAGPTAVVTIEALDRTGLWGRLLPEWGAIRDLPPRDVAHKW
MAV_3773|M.avium_104                ALDDLLVLLSAGPTTVATIEALDRTGLWGRLLPEWDAIRDLPPRDVAHKW
Mflv_4183|M.gilvum_PYR-GCK          ALKDLLVMLAAGPSAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIW
Mvan_2180|M.vanbaalenii_PYR-1       ALKDLLVMLAAGPSAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIW
MSMEG_2427|M.smegmatis_MC2_155      ALKDLLVLLAAGPAAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIW
TH_1479|M.thermoresistible__bu      ALNDLLVLLGAGPAAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDIVHVW
MAB_3238c|M.abscessus_ATCC_199      ALKDLLVLLESGRPALATIEALDRTGLWGRLFPEWGPVRDLPPRDIVHIW
MLBr_01630|M.leprae_Br4923          GDEEAVRWLARAAHIRPDGRHDAAGVLREELKNQNLRVSQLHAKLFYQPL
MUL_1336|M.ulcerans_Agy99           DDEEAVRWLARAAHIRPDGRHDAAGMLREELKHQNVRVSRLHAKLFYQPL
                                      .: :  *  .       .      *  .*  :   :  * .: . :  

Mb2942c|M.bovis_AF2122/97           TVDRHVVETAVHAAPLATRVARPDLLALG------ALLHDIGKG-RGTDH
Rv2918c|M.tuberculosis_H37Rv        TVDRHVVETAVHAAPLATRVARPDLLALG------ALLHDIGKG-RGTDH
MMAR_1789|M.marinum_M               TVDRHLIETAVQAAPLTTQVARPDLLALG------ALLHDIGKG-RGADH
MAV_3773|M.avium_104                TVDRHVIETTVNAAPLATRVARPDLLALG------ALLHDIGKG-RGVDH
Mflv_4183|M.gilvum_PYR-GCK          TVDRHLVETVSRASAFTTRVSRPDLLLLG------ALVHDIGKG-RGGDH
Mvan_2180|M.vanbaalenii_PYR-1       TVDRHLVETVSRASAFTTRVSRPDLLILG------ALVHDIGKG-RGGDH
MSMEG_2427|M.smegmatis_MC2_155      TVDRHLVETVSRASAFTTRVSRPDLLLLG------ALCHDIGKG-RGGDH
TH_1479|M.thermoresistible__bu      TVDRHLTETVAQASALTTRVSRPDLLLLG------ALLHDIGKG-RGGDH
MAB_3238c|M.abscessus_ATCC_199      TVDRHLVETVVQASAFTTRVSRPDLLVLG------ALVHDIGKG-RGGDH
MLBr_01630|M.leprae_Br4923          LESIGPASLEIR-HGMTSEAAERQLATLGYEGSQTALKHISALVNQSGRR
MUL_1336|M.ulcerans_Agy99           LESIAPAGLEIAGRGMTSEAAERQLAALGYEGPQTALKHMAALVNHSGRR
                                      .            :::..:. :*  **      ** *  .   :.  :

Mb2942c|M.bovis_AF2122/97           SVLGAELVIPVCTRLGLSP-PDVWTLSKLVRHHLLLPITATRRDLNDPKT
Rv2918c|M.tuberculosis_H37Rv        SVLGAELVIPVCTRLGLSP-PDVRTLSKLVRHHLLLPITATRRDLNDPKT
MMAR_1789|M.marinum_M               SVLGAEMVVAIGQRLGISA-PDIDLLSKLVRHHLLLPVVATRSDLNDPST
MAV_3773|M.avium_104                SVLGAGLALEIGPRLGMAP-ADVELLAQLVRHHLLLPVAATRSDLNDPKT
Mflv_4183|M.gilvum_PYR-GCK          SVIGAELAHQIGSRLGLWP-SDIKILAQVVRYHLLLPHTATRRDLQDAAT
Mvan_2180|M.vanbaalenii_PYR-1       SVIGAELADQIGSRLGLWP-SDIRVLSTLVRHHLLLPHTATRRDLQDPAT
MSMEG_2427|M.smegmatis_MC2_155      SVIGAELATQIGTRLGLWP-SDIDVLSKLVRYHLLLPETATRRDLQDPKT
TH_1479|M.thermoresistible__bu      SVIGAELAAQIGARLGLWP-SDIDILVKLVRHHLLLVRTATRRDLDDPRT
MAB_3238c|M.abscessus_ATCC_199      SVVGADLAVQIGTRLGLWP-SDVELLSKIVRYHLLLPNTATRRDLADPET
MLBr_01630|M.leprae_Br4923          GRVQSVLLPRLLNWMSYAPDPDGGLLAYRRLSEALSAETWYLSTLRDKPA
MUL_1336|M.ulcerans_Agy99           ARVQSVLLPRLLDWLSYAPDPDGGLLAYRRLSEALAPQSWYLSTLRDKPT
                                    . : : :   :   :.  . .*   *      . *         * *  :

Mb2942c|M.bovis_AF2122/97           IEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCR
Rv2918c|M.tuberculosis_H37Rv        IEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCR
MMAR_1789|M.marinum_M               ITRVSEALGGDPQLLEVLRALTEADSKATGPGVWSDWKASLVDDLVSRCR
MAV_3773|M.avium_104                IERVSKTLGEDPLLLEVLHALTEADSKATGPGVWSDWKASLIDDLVRRCR
Mflv_4183|M.gilvum_PYR-GCK          ISAVVDALDGDPAVLELLHVLAEADSLATGPGVWGDWKASLLGELVRRCR
Mvan_2180|M.vanbaalenii_PYR-1       IAAVVDALDGDLVVLELLHVLAEADSLATGPGVWGDWKASLIGELVRRCR
MSMEG_2427|M.smegmatis_MC2_155      IAAVVDALGGDMVVLELLDVLAEADSLATGPGVWGDWKASLIGDLVRRCR
TH_1479|M.thermoresistible__bu      IESVVDALGPDPVLLDLLHALVEADSLATGPGVWGEWKAALIGDLVRRCR
MAB_3238c|M.abscessus_ATCC_199      IDGVVNTLGGDLLLLELLQQLAEADSLATGPGVWGDWKASLIGELVRKCR
MLBr_01630|M.leprae_Br4923          VARRLMHVLGTSVYVPDLLMRAPEVIQSYGDGLAGPKLLEAEPAMVARAL
MUL_1336|M.ulcerans_Agy99           VGRRLMHVLGTSAFVPDLLMRAPEVIQNYGDSRTGPKLLETEPAAVARAL
                                    :      :      :  *           * .  .          * :. 

Mb2942c|M.bovis_AF2122/97           MVMAG------ESLPQAEPTAPHYLSLAADHGVHVEISPRDGERI-DAVI
Rv2918c|M.tuberculosis_H37Rv        MVMAG------ESLPQAEPTAPHYLSLAADHGVHVEISPRDGERI-DAVI
MMAR_1789|M.marinum_M               LAMAG------EPLPRADPEAPHYVSLSADHGVHVEIAPGESARMYQVVM
MAV_3773|M.avium_104                MVMAG------EPLPKVEPAAPQYLSLAADRGVHVQIKPGGGERL-DVVM
Mflv_4183|M.gilvum_PYR-GCK          MVMAG------EPLPHPDPVDPRFISLAGQVGVHVELTPTDTPHIYQVTM
Mvan_2180|M.vanbaalenii_PYR-1       LVMAG------EPLPHPDPVDPRFVALAGDGGVHVELTPAEHSHIYNVTM
MSMEG_2427|M.smegmatis_MC2_155      LVMAG------EPLPHPDPIDPRFLEIAADVGVHVELTPGDGQHIFNVTM
TH_1479|M.thermoresistible__bu      LVMAG------EPLPHPDPIDPQHLSLAARGGVHVDLVPGDGPHIYQVTL
MAB_3238c|M.abscessus_ATCC_199      LVMRG------EQLPEPDPIDPELLSLAADGGVQVRLVPAGSPHMYIVSL
MLBr_01630|M.leprae_Br4923          ITSAGRHTDPIRAIDAARSLRRRELARVGSADLLGLLEVTEVCKALTSVW
MUL_1336|M.ulcerans_Agy99           IASAGRYSDPLRAIAAARTLRRRELARIGSADLLGLLEVTEVCRALTSVW
                                    :.  *      . :    .   . :   .  .:   :      :      

Mb2942c|M.bovis_AF2122/97           VAPDERGLVS----------KAAAVLALNSLRVHSASVNVHQGVAITEFV
Rv2918c|M.tuberculosis_H37Rv        VAPDERGLVS----------KAAAVLALNSLRVHSASVNVHQGVAITEFV
MMAR_1789|M.marinum_M               AAPNKPGLVS----------KAAAVLALNSLGVHSAWVNSHEGVAITQFV
MAV_3773|M.avium_104                AAPDQRGLVS----------KAAAVLALNSLRIHSASASTHEGFAVVEFV
Mflv_4183|M.gilvum_PYR-GCK          IAPDSRGVLS----------KAAGVMALNSLRVHSASVNGHEGSAINSFV
Mvan_2180|M.vanbaalenii_PYR-1       IAPDSRGLLS----------KTAGVLALNSLRVHSASVNGHEGAAINTFV
MSMEG_2427|M.smegmatis_MC2_155      IAPDRRGLLS----------KAAGVLALNSLRVHSASVNSHEGSAINTFV
TH_1479|M.thermoresistible__bu      VAPDRRGLLS----------KAAGVLALNSLRVHSASVNSHHGSAINTFV
MAB_3238c|M.abscessus_ATCC_199      IAPDQRGLLS----------KAAGVLSLNSLRVFSASVASHAGSAINTFE
MLBr_01630|M.leprae_Br4923          VAVLQAALDAVIRAYLPDGDKAPAAIAVIGMGRLGGAELGYGSDADVMFV
MUL_1336|M.ulcerans_Agy99           VAVLQSALEAMIRANTPEGGRPLARIAVIGMGRLGGSELSYGSDADVMYV
                                     *    .: :          :. . ::: .:   ..    : . *   : 

Mb2942c|M.bovis_AF2122/97           VSPLFGSPPAAELVR----------QQFVGALNGDVDVLGMLQKRDSD--
Rv2918c|M.tuberculosis_H37Rv        VSPLFGSPPAAELVR----------QQFVGALNGDVDVLGMLQKRDSD--
MMAR_1789|M.marinum_M               VSPLFGTPAAADLLR----------QQFVGALSGDIDALAMVEKRDSE--
MAV_3773|M.avium_104                VSPLFGSPPEAGLLR----------QQFTGALGGDVDVLGTLEKRDSD--
Mflv_4183|M.gilvum_PYR-GCK          VSPRFGTPPAAELLR----------QQLILAIDGELDVMGALEKKE----
Mvan_2180|M.vanbaalenii_PYR-1       VSPRFGSPPAAELLR----------QQLILAIDGELDVMGALEKKE----
MSMEG_2427|M.smegmatis_MC2_155      VSPHFGSPPAADLLR----------QQFVLALDGDLDVIGSLERRERE--
TH_1479|M.thermoresistible__bu      VSPHFGAPPAANLLR----------QQLILALDGDLDVLAALERRDHDG-
MAB_3238c|M.abscessus_ATCC_199      VSPRFGSPPAAGLLR----------QQLISAIDGDTDIIAALDERERE--
MLBr_01630|M.leprae_Br4923          CEPAIGVEDAQALRWSGMIAERVCRLLRTPSVDPPLDVDANLRPEGRNGP
MUL_1336|M.ulcerans_Agy99           CEPASGVTDAQGVKWSTAVAEQVRAKLGTPSVDPPLEVDANLRPEGRNGP
                                     .*  *      :                 ::.   :  . :  .     

Mb2942c|M.bovis_AF2122/97           ----------------------AASLVSARAGDVQAG-------------
Rv2918c|M.tuberculosis_H37Rv        ----------------------AASLVSARAGDVQAG-------------
MMAR_1789|M.marinum_M               ----------------------ATSNASQRAGEVVAG-------------
MAV_3773|M.avium_104                ----------------------AVGAATRRAGEVQVG-------------
Mflv_4183|M.gilvum_PYR-GCK          ----------------------AESVATGRAGEVRAA-------------
Mvan_2180|M.vanbaalenii_PYR-1       ----------------------AESTATGRAGEIRAA-------------
MSMEG_2427|M.smegmatis_MC2_155      ----------------------AAQYPTTRAGEILAA-------------
TH_1479|M.thermoresistible__bu      -------------APGSHRPGEPAXXXVGVAAESIAAGLTAFEVGRHRAE
MAB_3238c|M.abscessus_ATCC_199      ----------------------SAQFATGVVGDAAPA-------------
MLBr_01630|M.leprae_Br4923          LVRTLGAYAAYYAQWAQPWEIQALLRAHAVAGDADLG-------------
MUL_1336|M.ulcerans_Agy99           LVRTLASYGAYYAQWAQAWEIQALLRAHAVAGDAALG-------------
                                                          .       ..:   .             

Mb2942c|M.bovis_AF2122/97           --------------------VPVTRTAAPPRILWLDT-----AAPAKLIL
Rv2918c|M.tuberculosis_H37Rv        --------------------VPVTRTAAPPRILWLDT-----AAPAKLIL
MMAR_1789|M.marinum_M               --------------------VPVTRSTAPPRILWLDS-----AAPDQLVL
MAV_3773|M.avium_104                --------------------VPVTRSTAPPRILWVDT-----AAADQLIV
Mflv_4183|M.gilvum_PYR-GCK          --------------------VPINAPTAPPKVLWHEP-----SGSGHVVA
Mvan_2180|M.vanbaalenii_PYR-1       --------------------VPINPPTAPPRVLWHEG-----AGAGQVVA
MSMEG_2427|M.smegmatis_MC2_155      --------------------VPANHVPAPPRLLWADG-----SNPGELIV
TH_1479|M.thermoresistible__bu      LIATAGGISYVDDSKATNPHAAAASIAAHPRVVWIAGGLLKGAAVDELVA
MAB_3238c|M.abscessus_ATCC_199      --------------------VPTNYAPAPPRIRWFEP----AGNADQQIV
MLBr_01630|M.leprae_Br4923          -------QRFLLMADKMRYPPDGVSAEAVREIRRMKARVEAERLPRGADP
MUL_1336|M.ulcerans_Agy99           -------QRFLLLVDHTRYPPDGVSAEAVHEIRRIKARVESERLPRGADP
                                                               *  .:                  

Mb2942c|M.bovis_AF2122/97           EVRAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST---------
Rv2918c|M.tuberculosis_H37Rv        EVRAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST---------
MMAR_1789|M.marinum_M               EVRSMDRPGLLA-----LLTRALERAGADIVWAKVNTFGST---------
MAV_3773|M.avium_104                EVRAMDRLGLLA-----LLTRALERAGTDIVWAKVNTFGST---------
Mflv_4183|M.gilvum_PYR-GCK          EIRATDRTGLLA-----VLTRVFERAGVDIAWAKVTTMGSS---------
Mvan_2180|M.vanbaalenii_PYR-1       EIRATDRAGLLA-----VLTRVLERAGVDIAWAKVTTLGSS---------
MSMEG_2427|M.smegmatis_MC2_155      QIRTIDRAGLLA-----RLTAVFERDGVDIAWAKVTTLGSS---------
TH_1479|M.thermoresistible__bu      EVADRLAGXXLIGRDREIIAQALSRHAPEVPVVSVVTGDDSGMQATAGAP
MAB_3238c|M.abscessus_ATCC_199      EIRTSDAPGLLA-----RITATLERHGVDIAWAKVNTLGSS---------
MLBr_01630|M.leprae_Br4923          HTHTKLGRGGLADIEWTVQLMQLRHAHELPALHKTSTLESLDAIAAANLI
MUL_1336|M.ulcerans_Agy99           NTHTKLGRGGLADIEWTVQLLQLQNAHEIEALHNTSTLESLDAIAEAKLV
                                    .         *           :          .. *  .          

Mb2942c|M.bovis_AF2122/97           ------AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVG
Rv2918c|M.tuberculosis_H37Rv        ------AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVG
MMAR_1789|M.marinum_M               ------AADVFCVTVSAGLEEPQARAA-MEQQLSAVLGGSADVLLDEPVG
MAV_3773|M.avium_104                ------AADAFCVTA-GDAG---ARDA-VEQSLLTVLGGPAVEVLEEPVG
Mflv_4183|M.gilvum_PYR-GCK          ------VIDVFGIVLPAG-EDAVRES--LEKQLLAVLPAPPQPKPVREEA
Mvan_2180|M.vanbaalenii_PYR-1       ------VVDAFGIVLPAD-GAAARQN--LERELFAVLPAPP-AKPAEVEA
MSMEG_2427|M.smegmatis_MC2_155      ------VVDAFGITTADGRTEQVRQE--LERDLYAVLPTPPPAKPAEQAS
TH_1479|M.thermoresistible__bu      VNAVTRVVEATEPIGPAVMTAAVAAARALASPGDTVLLAPAGASFDQFSG
MAB_3238c|M.abscessus_ATCC_199      ------VVDTFCLSTGPE-QAVLEAA--IASVLPAVAPQPKKAAAS----
MLBr_01630|M.leprae_Br4923          PEADVDLLRQAWLTATRARNALVLVRGKTTDQLPGPGRQLNAVAVAAGWP
MUL_1336|M.ulcerans_Agy99           AEDEVKLLRQAWLTATRARNALVLVRGKPTDQLPGPGRQLNAVAVAAGWH
                                                                                      

Mb2942c|M.bovis_AF2122/97           D---------------------------
Rv2918c|M.tuberculosis_H37Rv        D---------------------------
MMAR_1789|M.marinum_M               D---------------------------
MAV_3773|M.avium_104                D---------------------------
Mflv_4183|M.gilvum_PYR-GCK          S---------------------------
Mvan_2180|M.vanbaalenii_PYR-1       S---------------------------
MSMEG_2427|M.smegmatis_MC2_155      ----------------------------
TH_1479|M.thermoresistible__bu      YADRGDAFAAAVRAAIR-----------
MAB_3238c|M.abscessus_ATCC_199      ----------------------------
MLBr_01630|M.leprae_Br4923          SDDGSEFLDNYLRVTRRAKTFVRKVFGS
MUL_1336|M.ulcerans_Agy99           NDDGGEFLDNYLRVTRRAKAVVRKVFGS