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M. vanbaalenii PYR-1 Mvan_2180 (-)

annotation: PII uridylyl-transferase
coordinates: 2328547 - 2331015
length: 822

MKEQKSQPAAGAPRWERPAAGSLRPATDLVAAADQLLSGSRQLDAAALRDALLDLYDFWLTTKASEIGIT
ATSGFAIVATGGLGRGELLPYSDLDLMLLHDNMPPEIVSEVAELLWYPLWDANIRLDHSVRTVPEALRVA
GTDISAGLAMLEARHIAGDGDLSSLLIGGARRQWRTGIASRFDELVEHTRARWQRSGEIAHRAEPDLKCG
RGGLRDVQLLNALAIAQLADVYPSRSLASPTETLGEAHLSLLNVRTELHRVAGRGRELLLAQHADEIGAA
LHIGDRFDLARMLSDAARTVSYYVDAGIRTAANALPRRGLAVLRRPVRRPLDEGVIEFNGEVILARDARP
ERDPGLILRVAAASATTGLPMAASTLSRLVEAAPELRTPWPGQALKDLLVMLAAGPSAVATIEALDRTGL
WGRLFPEWGAVRDLPPRDVVHIWTVDRHLVETVSRASAFTTRVSRPDLLILGALVHDIGKGRGGDHSVIG
AELADQIGSRLGLWPSDIRVLSTLVRHHLLLPHTATRRDLQDPATIAAVVDALDGDLVVLELLHVLAEAD
SLATGPGVWGDWKASLIGELVRRCRLVMAGEPLPHPDPVDPRFVALAGDGGVHVELTPAEHSHIYNVTMI
APDSRGLLSKTAGVLALNSLRVHSASVNGHEGAAINTFVVSPRFGSPPAAELLRQQLILAIDGELDVMGA
LEKKEAESTATGRAGEIRAAVPINPPTAPPRVLWHEGAGAGQVVAEIRATDRAGLLAVLTRVLERAGVDI
AWAKVTTLGSSVVDAFGIVLPADGAAARQNLERELFAVLPAPPAKPAEVEAS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2180--100% (822)PII uridylyl-transferase
M. vanbaalenii PYR-1Mvan_6061-1e-0528.36% (342) metal dependent phosphohydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2942cglnD0.063.54% (790) PII uridylyl-transferase
M. gilvum PYR-GCKMflv_4183-0.089.08% (824) PII uridylyl-transferase
M. tuberculosis H37RvRv2918cglnD0.063.67% (790) PII uridylyl-transferase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3238c-0.070.79% (801) PII uridylyl-transferase
M. marinum MMMAR_1789glnD0.063.14% (795) uridylyltransferase GlnD
M. avium 104MAV_3773glnD0.062.29% (814) PII uridylyl-transferase
M. smegmatis MC2 155MSMEG_2427glnD0.082.89% (824) PII uridylyl-transferase
M. thermoresistible (build 8)TH_1479glnD0.077.44% (718) PROBABLE
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_2180|M.vanbaalenii_PYR-1       MKEQKSQPAAGAPRWERPAAGSLRPATDLVAAADQLLSG-SRQLDAAALR
Mflv_4183|M.gilvum_PYR-GCK          MKDSTSKPAAGASRWERPAAVSSRPATDLVAAAEQLLAGGARPLDSAALR
MSMEG_2427|M.smegmatis_MC2_155      MAEHKTQSAG--ASHKGAPAGSSRPANDLAAAVSQLLTGGPRQLDSAALR
TH_1479|M.thermoresistible__bu      MTEQTPGPASGSFPAKDPEAVCSKPARDLVAATERLLAGGARQLDAASLR
MAB_3238c|M.abscessus_ATCC_199      ----------------------MGAATDLVAARAQLLGD-SGRLNAAAIR
Mb2942c|M.bovis_AF2122/97           MEAE-----------------SPCAASDLAVARRELLSGNHRELDPVGLR
Rv2918c|M.tuberculosis_H37Rv        MEAE-----------------SPCAASDLAVARRELLSGNHRELDPVGLR
MMAR_1789|M.marinum_M               MEPG-----------------SVRAASDLAAARRQLLSDDHRDMDPAELR
MAV_3773|M.avium_104                MTPTGP---------DPSGHQNACGAVDLAASRRQLLSEGG-KLHAAELR
                                                             * **..:  .**      :... :*

Mvan_2180|M.vanbaalenii_PYR-1       DALLDLYDFWLTTKASEIGITATSGFAIVATGGLGRGELLPYSDLDLMLL
Mflv_4183|M.gilvum_PYR-GCK          DALLDLHDFWLTTKATEIGITATSGFAIVATGGLGRGELLPYSDLDLMLL
MSMEG_2427|M.smegmatis_MC2_155      DALLDLYEFWLTTKATELGITADSGFAIVATGGLGRGEMLPYSDLDLMLL
TH_1479|M.thermoresistible__bu      YALLDLHELWLNTKAAEIGITPVSGFSIVATGGLGRGELVPHSDLDLMLL
MAB_3238c|M.abscessus_ATCC_199      EAMTDLNELWLTTKAAEVGITDSSGFAIVALGGLGRREMLPYSDLDLVLL
Mb2942c|M.bovis_AF2122/97           QTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSDLDVLLL
Rv2918c|M.tuberculosis_H37Rv        QTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSDLDVLLL
MMAR_1789|M.marinum_M               QAWLDLHESWLIAKAAQIGIADDSGYAIVGVGGLGRRELLPYSDLDLVLV
MAV_3773|M.avium_104                HAWLDLHESWLAAKAAQIGIADDSGFALVGIGGLGRHELLPYSDLDLMLL
                                     :  ** : **  ** ::**:  **:::*. ***** *::*:****::*:

Mvan_2180|M.vanbaalenii_PYR-1       HDN-MPPEIVSEVAELLWYPLWDANIRLDHSVRTVPEALRVAGTDISAGL
Mflv_4183|M.gilvum_PYR-GCK          HDN-MPAEIVGEVAELLWYPLWDANIRLDHSVRTVPEALRVAGEDISAGL
MSMEG_2427|M.smegmatis_MC2_155      HDN-MPVDVVTEVAEKLWYPLWDANIRLDHSVRTVPEALKVAGEDISVGL
TH_1479|M.thermoresistible__bu      HDG-MPTELVGRIAEQLWYPLWDANIRIDHSVRTVAEALAVADADIAAGL
MAB_3238c|M.abscessus_ATCC_199      HDENIAPETLSEVADGLWYPLWDANIRLDHSVRTVADTLHVAGQEMSAAL
Mb2942c|M.bovis_AF2122/97           HDG-KPADILRPVADRLWYPLWDANIRLDHSVRTVSEALTIANSDLMAAL
Rv2918c|M.tuberculosis_H37Rv        HDG-KPADILRPVADRLWYPLWDANIRLDHSVRTVSEALTIANSDLMAAL
MMAR_1789|M.marinum_M               HDG-KPVEELGDVADALWYPLWDANIRLDHSVRTVSDALGVAGADMAAAL
MAV_3773|M.avium_104                HDN-KSDEVLQRVADALWYPLWDANVRLDHSVRTVSGALGVANGDMIAAL
                                    **   . : :  :*: *********:*:*******. :* :*. :: ..*

Mvan_2180|M.vanbaalenii_PYR-1       AMLEARHIAGDGDLSSLLIGGARRQWRTGIASRFDELVEHTRARWQRSGE
Mflv_4183|M.gilvum_PYR-GCK          AMLEARHIAGDADLSSLLIGGARRQWRTGIAPRFEELVEHARARWQRSGE
MSMEG_2427|M.smegmatis_MC2_155      AMLDVRHIAGDADLSSLLVGGARRQWRIGIASRFEELVEHAQARWQRSGQ
TH_1479|M.thermoresistible__bu      AMLEARHIAGDADLSALVIDGARRHWRTTIASRFDELIDHTRARWERSGQ
MAB_3238c|M.abscessus_ATCC_199      ALLDARHIAGDAQLSSLMIGGVRQQWRSQIRTRLDELVEYTQARWRRSGE
Mb2942c|M.bovis_AF2122/97           GMLEARHIAGDQQLSFALIDGVRRQWRNGIRSRMGELVEMTYARWRRCGR
Rv2918c|M.tuberculosis_H37Rv        GMLEARHIAGDQQLSFALIDGVRRQWRNGIRSRMGELVEMTYARWRRCGR
MMAR_1789|M.marinum_M               GMLEARHIVGDQQLSASLIDGVRRQWRSGIRSRMNELVDMTHDRWLRCGR
MAV_3773|M.avium_104                GMLDARHVAGDARLSDELIAGARRQWRSAIRSRMDELVEMTQARWDRCGR
                                    .:*:.**:.**  **  :: *.*::**  * .*: **:: :  ** *.*.

Mvan_2180|M.vanbaalenii_PYR-1       IAHRAEPDLKCGRGGLRDVQLLNALAIAQLADVYPSRSLASPTETLGEAH
Mflv_4183|M.gilvum_PYR-GCK          IAHRAEPDLKCGRGGLRDVQLLNALAIAQLADVYPSRSLASPTETLGEAN
MSMEG_2427|M.smegmatis_MC2_155      IAHRAEPDLKSGRGGLRDVQLLNALAIAQLADVYPSRALASPTGTLGGAH
TH_1479|M.thermoresistible__bu      IAHRAEPDLKCGRGGLRDVQLLNALAIAQLADGYPSSSLASPTGTLGDAH
MAB_3238c|M.abscessus_ATCC_199      IAHRAEPDLKSGRGGLRDVQLLRALAIAQLTDSGLAKSFDG-------AH
Mb2942c|M.bovis_AF2122/97           IAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHTDRPAGSLDGAY
Rv2918c|M.tuberculosis_H37Rv        IAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHTDLPAGSLDGAY
MMAR_1789|M.marinum_M               VANRAEPDLKSGRGGLRDVQLLDALAIAQLIDRHGLVTPDMPVGSLDAAY
MAV_3773|M.avium_104                IAQRAEPDLKSGRGGLRDVQLLDALGVAQLIDRHGMARPESPGGSLDDAH
                                    :*:******* *********** **.:*** *                * 

Mvan_2180|M.vanbaalenii_PYR-1       LSLLNVRTELHRVAGRGRELLLAQHADEIGAALHIGDRFDLARMLSDAAR
Mflv_4183|M.gilvum_PYR-GCK          LALLNVRTELHRVAGRGRELLLAQHADEIGASLRIGDRFDLARTLSDAAR
MSMEG_2427|M.smegmatis_MC2_155      LALLNVRTELHRVSGRGRELLLAQHADEIGAALRIGDRFDLARMLSDAAR
TH_1479|M.thermoresistible__bu      LALLDVRTELHRIAGRGRDLLQAQYADEIAAALRIGDRFDLARLLSDAAR
MAB_3238c|M.abscessus_ATCC_199      SVILDVRTELHRVAGRERDQLLAQFADEIGAALRIGDRFDLARMLSDAAR
Mb2942c|M.bovis_AF2122/97           RTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSAGR
Rv2918c|M.tuberculosis_H37Rv        RTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSAGR
MMAR_1789|M.marinum_M               LTLLNVRTELHRVSGRGRDLLLAQHADDISAALHFGDRFDLARMLSSAGR
MAV_3773|M.avium_104                LTLLDVRTELHRVSGRGLDQLLAQYGDELSAALHIGDRFDLARKLSDASR
                                      :*:*******::**  : * **..*::.*:* :******** **.*.*

Mvan_2180|M.vanbaalenii_PYR-1       TVSYYVDAGIRTAANALPRRGLAVL-RRPVRRPLDEGVIEFNGEVILARD
Mflv_4183|M.gilvum_PYR-GCK          TVSYYVDAGIRTAANSLPRRGLAAL-RRPVRRPLDEGVIEFAGEVILARD
MSMEG_2427|M.smegmatis_MC2_155      TVSYYVDSGIRTAANALPRRGFAAL-RRPVRRPLDEGVIEFAGEVILARD
TH_1479|M.thermoresistible__bu      TVSYYVDSGLRTAANALPRRGFAAL-RRPLRRPLDEGVVEYAGEVILARD
MAB_3238c|M.abscessus_ATCC_199      TISYSVDVGLRAAANSIPRRGISAL-RRTVRRPIDEGVVEHAGEVVLARD
Mb2942c|M.bovis_AF2122/97           TIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARD
Rv2918c|M.tuberculosis_H37Rv        TIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARD
MMAR_1789|M.marinum_M               TIAYHAESGLRTACNALPRRGISALRRRPKRRPLDEGVVECANEIVLARD
MAV_3773|M.avium_104                TIAYHAETGLRTAENALPRRGVSALVRRPKRRPLDEGVVEYAGEIVLARD
                                    *:.* .: *:*:* *::****.:.* **. ***:****:*  .*::****

Mvan_2180|M.vanbaalenii_PYR-1       ARPERDPGLILRVAAASATTGLPMAASTLSRLVEAAPELRTPWPGQALKD
Mflv_4183|M.gilvum_PYR-GCK          ARPERDPGLILRVAAASATTGLPIAGSTLSRLVEAAPELRTPWPRQALKD
MSMEG_2427|M.smegmatis_MC2_155      ARPERDPGLVLRVAAASATTGLPIAVSTLSRLAETAPELRTPWPSQALKD
TH_1479|M.thermoresistible__bu      ARPARDPGLILRVAAASATTGLPIAASTLSRLAATAPELRAPWPRPALND
MAB_3238c|M.abscessus_ATCC_199      ARPERDPSLILRVAAASATTGLPIAASTLARLAESAPELRTPWPREALKD
Mb2942c|M.bovis_AF2122/97           AEPEHDPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALDD
Rv2918c|M.tuberculosis_H37Rv        AEPEHDPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALDD
MMAR_1789|M.marinum_M               AQPEQDAGLVLRVAAAAAHAGLPIGAATLRRLADSAAELPTPWPREVLDD
MAV_3773|M.avium_104                ARPDTDVGLVLRVAAASASTGLPIGAATLSRLAAAAPEMPEPWPREALDD
                                    *.*  * .*:******:* :***:. :** **. :..::  ***  .*.*

Mvan_2180|M.vanbaalenii_PYR-1       LLVMLAAGPSAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVDR
Mflv_4183|M.gilvum_PYR-GCK          LLVMLAAGPSAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVDR
MSMEG_2427|M.smegmatis_MC2_155      LLVLLAAGPAAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVDR
TH_1479|M.thermoresistible__bu      LLVLLGAGPAAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDIVHVWTVDR
MAB_3238c|M.abscessus_ATCC_199      LLVLLESGRPALATIEALDRTGLWGRLFPEWGPVRDLPPRDIVHIWTVDR
Mb2942c|M.bovis_AF2122/97           LLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVDR
Rv2918c|M.tuberculosis_H37Rv        LLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVDR
MMAR_1789|M.marinum_M               LLVVLLAGPTAVVTIEALDRTGLWGRLLPEWGAIRDLPPRDVAHKWTVDR
MAV_3773|M.avium_104                LLVLLSAGPTTVATIEALDRTGLWGRLLPEWDAIRDLPPRDVAHKWTVDR
                                    ***:* :* .:: **************:*** .:*******:.* *****

Mvan_2180|M.vanbaalenii_PYR-1       HLVETVSRASAFTTRVSRPDLLILGALVHDIGKGRGGDHSVIGAELADQI
Mflv_4183|M.gilvum_PYR-GCK          HLVETVSRASAFTTRVSRPDLLLLGALVHDIGKGRGGDHSVIGAELAHQI
MSMEG_2427|M.smegmatis_MC2_155      HLVETVSRASAFTTRVSRPDLLLLGALCHDIGKGRGGDHSVIGAELATQI
TH_1479|M.thermoresistible__bu      HLTETVAQASALTTRVSRPDLLLLGALLHDIGKGRGGDHSVIGAELAAQI
MAB_3238c|M.abscessus_ATCC_199      HLVETVVQASAFTTRVSRPDLLVLGALVHDIGKGRGGDHSVVGADLAVQI
Mb2942c|M.bovis_AF2122/97           HVVETAVHAAPLATRVARPDLLALGALLHDIGKGRGTDHSVLGAELVIPV
Rv2918c|M.tuberculosis_H37Rv        HVVETAVHAAPLATRVARPDLLALGALLHDIGKGRGTDHSVLGAELVIPV
MMAR_1789|M.marinum_M               HLIETAVQAAPLTTQVARPDLLALGALLHDIGKGRGADHSVLGAEMVVAI
MAV_3773|M.avium_104                HVIETTVNAAPLATRVARPDLLALGALLHDIGKGRGVDHSVLGAGLALEI
                                    *: **. .*:.::*:*:***** **** ******** ****:** :.  :

Mvan_2180|M.vanbaalenii_PYR-1       GSRLGLWPSDIRVLSTLVRHHLLLPHTATRRDLQDPATIAAVVDALDGDL
Mflv_4183|M.gilvum_PYR-GCK          GSRLGLWPSDIKILAQVVRYHLLLPHTATRRDLQDAATISAVVDALDGDP
MSMEG_2427|M.smegmatis_MC2_155      GTRLGLWPSDIDVLSKLVRYHLLLPETATRRDLQDPKTIAAVVDALGGDM
TH_1479|M.thermoresistible__bu      GARLGLWPSDIDILVKLVRHHLLLVRTATRRDLDDPRTIESVVDALGPDP
MAB_3238c|M.abscessus_ATCC_199      GTRLGLWPSDVELLSKIVRYHLLLPNTATRRDLADPETIDGVVNTLGGDL
Mb2942c|M.bovis_AF2122/97           CTRLGLSPPDVWTLSKLVRHHLLLPITATRRDLNDPKTIEAVSEALGGDP
Rv2918c|M.tuberculosis_H37Rv        CTRLGLSPPDVRTLSKLVRHHLLLPITATRRDLNDPKTIEAVSEALGGDP
MMAR_1789|M.marinum_M               GQRLGISAPDIDLLSKLVRHHLLLPVVATRSDLNDPSTITRVSEALGGDP
MAV_3773|M.avium_104                GPRLGMAPADVELLAQLVRHHLLLPVAATRSDLNDPKTIERVSKTLGEDP
                                      ***: ..*:  *  :**:****  .*** ** *. **  * .:*. * 

Mvan_2180|M.vanbaalenii_PYR-1       VVLELLHVLAEADSLATGPGVWGDWKASLIGELVRRCRLVMAGEPLPHPD
Mflv_4183|M.gilvum_PYR-GCK          AVLELLHVLAEADSLATGPGVWGDWKASLLGELVRRCRMVMAGEPLPHPD
MSMEG_2427|M.smegmatis_MC2_155      VVLELLDVLAEADSLATGPGVWGDWKASLIGDLVRRCRLVMAGEPLPHPD
TH_1479|M.thermoresistible__bu      VLLDLLHALVEADSLATGPGVWGEWKAALIGDLVRRCRLVMAGEPLPHPD
MAB_3238c|M.abscessus_ATCC_199      LLLELLQQLAEADSLATGPGVWGDWKASLIGELVRKCRLVMRGEQLPEPD
Mb2942c|M.bovis_AF2122/97           QLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVMAGESLPQAE
Rv2918c|M.tuberculosis_H37Rv        QLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVMAGESLPQAE
MMAR_1789|M.marinum_M               QLLEVLRALTEADSKATGPGVWSDWKASLVDDLVSRCRLAMAGEPLPRAD
MAV_3773|M.avium_104                LLLEVLHALTEADSKATGPGVWSDWKASLIDDLVRRCRMVMAGEPLPKVE
                                     :*::*  * **** *******.:***:*:.:** :**:.* ** **. :

Mvan_2180|M.vanbaalenii_PYR-1       PVDPRFVALAGDGGVHVELTPAEHSHIYNVTMIAPDSRGLLSKTAGVLAL
Mflv_4183|M.gilvum_PYR-GCK          PVDPRFISLAGQVGVHVELTPTDTPHIYQVTMIAPDSRGVLSKAAGVMAL
MSMEG_2427|M.smegmatis_MC2_155      PIDPRFLEIAADVGVHVELTPGDGQHIFNVTMIAPDRRGLLSKAAGVLAL
TH_1479|M.thermoresistible__bu      PIDPQHLSLAARGGVHVDLVPGDGPHIYQVTLVAPDRRGLLSKAAGVLAL
MAB_3238c|M.abscessus_ATCC_199      PIDPELLSLAADGGVQVRLVPAGSPHMYIVSLIAPDQRGLLSKAAGVLSL
Mb2942c|M.bovis_AF2122/97           PTAPHYLSLAADHGVHVEISPRDGERI-DAVIVAPDERGLVSKAAAVLAL
Rv2918c|M.tuberculosis_H37Rv        PTAPHYLSLAADHGVHVEISPRDGERI-DAVIVAPDERGLVSKAAAVLAL
MMAR_1789|M.marinum_M               PEAPHYVSLSADHGVHVEIAPGESARMYQVVMAAPNKPGLVSKAAAVLAL
MAV_3773|M.avium_104                PAAPQYLSLAADRGVHVQIKPGGGERL-DVVMAAPDQRGLVSKAAAVLAL
                                    *  *. : ::.  **:* : *    ::  . : **:  *::**:*.*::*

Mvan_2180|M.vanbaalenii_PYR-1       NSLRVHSASVNGHEGAAINTFVVSPRFGSPPAAELLRQQLILAIDGELDV
Mflv_4183|M.gilvum_PYR-GCK          NSLRVHSASVNGHEGSAINSFVVSPRFGTPPAAELLRQQLILAIDGELDV
MSMEG_2427|M.smegmatis_MC2_155      NSLRVHSASVNSHEGSAINTFVVSPHFGSPPAADLLRQQFVLALDGDLDV
TH_1479|M.thermoresistible__bu      NSLRVHSASVNSHHGSAINTFVVSPHFGAPPAANLLRQQLILALDGDLDV
MAB_3238c|M.abscessus_ATCC_199      NSLRVFSASVASHAGSAINTFEVSPRFGSPPAAGLLRQQLISAIDGDTDI
Mb2942c|M.bovis_AF2122/97           NSLRVHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDV
Rv2918c|M.tuberculosis_H37Rv        NSLRVHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDV
MMAR_1789|M.marinum_M               NSLGVHSAWVNSHEGVAITQFVVSPLFGTPAAADLLRQQFVGALSGDIDA
MAV_3773|M.avium_104                NSLRIHSASASTHEGFAVVEFVVSPLFGSPPEAGLLRQQFTGALGGDVDV
                                    *** :.** .  * * *:  * *** **:*. * *:***:  *:.*: * 

Mvan_2180|M.vanbaalenii_PYR-1       MGALEKKE------------AESTATGRAGEIRAA---------------
Mflv_4183|M.gilvum_PYR-GCK          MGALEKKE------------AESVATGRAGEVRAA---------------
MSMEG_2427|M.smegmatis_MC2_155      IGSLERRERE----------AAQYPTTRAGEILAA---------------
TH_1479|M.thermoresistible__bu      LAALERRDHDGAPGSHRPGEPAXXXVGVAAESIAAGLTAFEVGRHRAELI
MAB_3238c|M.abscessus_ATCC_199      IAALDERERE----------SAQFATGVVGDAAPA---------------
Mb2942c|M.bovis_AF2122/97           LGMLQKRDSD----------AASLVSARAGDVQAG---------------
Rv2918c|M.tuberculosis_H37Rv        LGMLQKRDSD----------AASLVSARAGDVQAG---------------
MMAR_1789|M.marinum_M               LAMVEKRDSE----------ATSNASQRAGEVVAG---------------
MAV_3773|M.avium_104                LGTLEKRDSD----------AVGAATRRAGEVQVG---------------
                                    :. ::.::            .       ..:   .               

Mvan_2180|M.vanbaalenii_PYR-1       ------------------VPINPPTAPPRVLWHEG-----AGAGQVVAEI
Mflv_4183|M.gilvum_PYR-GCK          ------------------VPINAPTAPPKVLWHEP-----SGSGHVVAEI
MSMEG_2427|M.smegmatis_MC2_155      ------------------VPANHVPAPPRLLWADG-----SNPGELIVQI
TH_1479|M.thermoresistible__bu      ATAGGISYVDDSKATNPHAAAASIAAHPRVVWIAGGLLKGAAVDELVAEV
MAB_3238c|M.abscessus_ATCC_199      ------------------VPTNYAPAPPRIRWFEP----AGNADQQIVEI
Mb2942c|M.bovis_AF2122/97           ------------------VPVTRTAAPPRILWLDT-----AAPAKLILEV
Rv2918c|M.tuberculosis_H37Rv        ------------------VPVTRTAAPPRILWLDT-----AAPAKLILEV
MMAR_1789|M.marinum_M               ------------------VPVTRSTAPPRILWLDS-----AAPDQLVLEV
MAV_3773|M.avium_104                ------------------VPVTRSTAPPRILWVDT-----AAADQLIVEV
                                                      ..    .* *:: *        .   . : ::

Mvan_2180|M.vanbaalenii_PYR-1       RATDRAGLLA-----VLTRVLERAGVDIAWAKVTTLGSS-----------
Mflv_4183|M.gilvum_PYR-GCK          RATDRTGLLA-----VLTRVFERAGVDIAWAKVTTMGSS-----------
MSMEG_2427|M.smegmatis_MC2_155      RTIDRAGLLA-----RLTAVFERDGVDIAWAKVTTLGSS-----------
TH_1479|M.thermoresistible__bu      ADRLAGXXLIGRDREIIAQALSRHAPEVPVVSVVTGDDSGMQATAGAPVN
MAB_3238c|M.abscessus_ATCC_199      RTSDAPGLLA-----RITATLERHGVDIAWAKVNTLGSS-----------
Mb2942c|M.bovis_AF2122/97           RAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST-----------
Rv2918c|M.tuberculosis_H37Rv        RAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST-----------
MMAR_1789|M.marinum_M               RSMDRPGLLA-----LLTRALERAGADIVWAKVNTFGST-----------
MAV_3773|M.avium_104                RAMDRLGLLA-----LLTRALERAGTDIVWAKVNTFGST-----------
                                            *       :: .:.  .  :  ..* * ..:           

Mvan_2180|M.vanbaalenii_PYR-1       ----VVDAFGIVLPAD-GAAARQN--LERELFAVLPAPP-AKPAEVEAS-
Mflv_4183|M.gilvum_PYR-GCK          ----VIDVFGIVLPAG-EDAVRES--LEKQLLAVLPAPPQPKPVREEAS-
MSMEG_2427|M.smegmatis_MC2_155      ----VVDAFGITTADGRTEQVRQE--LERDLYAVLPTPPPAKPAEQAS--
TH_1479|M.thermoresistible__bu      AVTRVVEATEPIGPAVMTAAVAAARALASPGDTVLLAPAGASFDQFSGYA
MAB_3238c|M.abscessus_ATCC_199      ----VVDTFCLSTGPE-QAVLEAA--IASVLPAVAPQPKKAAAS------
Mb2942c|M.bovis_AF2122/97           ----AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVGD-
Rv2918c|M.tuberculosis_H37Rv        ----AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVGD-
MMAR_1789|M.marinum_M               ----AADVFCVTVSAGLEEPQARAA-MEQQLSAVLGGSADVLLDEPVGD-
MAV_3773|M.avium_104                ----AADAFCVTA-GDAG---ARDA-VEQSLLTVLGGPAVEVLEEPVGD-
                                        . :.                  :      *   .            

Mvan_2180|M.vanbaalenii_PYR-1       ---------------
Mflv_4183|M.gilvum_PYR-GCK          ---------------
MSMEG_2427|M.smegmatis_MC2_155      ---------------
TH_1479|M.thermoresistible__bu      DRGDAFAAAVRAAIR
MAB_3238c|M.abscessus_ATCC_199      ---------------
Mb2942c|M.bovis_AF2122/97           ---------------
Rv2918c|M.tuberculosis_H37Rv        ---------------
MMAR_1789|M.marinum_M               ---------------
MAV_3773|M.avium_104                ---------------