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M. bovis AF2122 / 97 Mb2942c (glnD)

annotation: PII uridylyl-transferase
coordinates: 3184770 - 3187196
length: 808

MEAESPCAASDLAVARRELLSGNHRELDPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRR
ELLPYSDLDVLLLHDGKPADILRPVADRLWYPLWDANIRLDHSVRTVSEALTIANSDLMAALGMLEARHI
AGDQQLSFALIDGVRRQWRNGIRSRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALA
QLIDRHGIGHTDRPAGSLDGAYRTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSA
GRTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARDAEPEHDPGLVLRVAAASA
DTGLPIGAATLSRLAASVPDLPTPWPQEALDDLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLP
PRDVAHKWTVDRHVVETAVHAAPLATRVARPDLLALGALLHDIGKGRGTDHSVLGAELVIPVCTRLGLSP
PDVWTLSKLVRHHLLLPITATRRDLNDPKTIEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKAS
LVDDLVRRCRMVMAGESLPQAEPTAPHYLSLAADHGVHVEISPRDGERIDAVIVAPDERGLVSKAAAVLA
LNSLRVHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSDAASLVSARA
GDVQAGVPVTRTAAPPRILWLDTAAPAKLILEVRAMDRAGLLALLAGALEGAGAGIVWAKVNTFGSTAAD
VFCVTVPAELDARAAVEQHLLEVLGASVDVVVDEPVGD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2942cglnD-100% (808)PII uridylyl-transferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4183-0.062.81% (796) PII uridylyl-transferase
M. tuberculosis H37RvRv2918cglnD0.099.75% (808) PII uridylyl-transferase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3238c-0.061.74% (792) PII uridylyl-transferase
M. marinum MMMAR_1789glnD0.077.71% (812) uridylyltransferase GlnD
M. avium 104MAV_3773glnD0.075.90% (805) PII uridylyl-transferase
M. smegmatis MC2 155MSMEG_2427glnD0.065.25% (774) PII uridylyl-transferase
M. thermoresistible (build 8)TH_1479glnD0.066.19% (695) PROBABLE
M. ulcerans Agy99MUL_1336glnE9e-0525.71% (315) glutamate-ammonia-ligase adenylyltransferase GlnE
M. vanbaalenii PYR-1Mvan_2180-0.063.54% (790) PII uridylyl-transferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2942c|M.bovis_AF2122/97           ------MEAE-----------------SPCAASDLAVARRELLSGNHREL
Rv2918c|M.tuberculosis_H37Rv        ------MEAE-----------------SPCAASDLAVARRELLSGNHREL
MMAR_1789|M.marinum_M               ------MEPG-----------------SVRAASDLAAARRQLLSDDHRDM
MAV_3773|M.avium_104                ------MTPTGP---------DPSGHQNACGAVDLAASRRQLLSEGG-KL
Mflv_4183|M.gilvum_PYR-GCK          ------MKDSTSKPAAGASRWERPAAVSSRPATDLVAAAEQLLAGGARPL
Mvan_2180|M.vanbaalenii_PYR-1       ------MKEQKSQPAAGAPRWERPAAGSLRPATDLVAAADQLLSG-SRQL
MSMEG_2427|M.smegmatis_MC2_155      ------MAEHKTQSAG--ASHKGAPAGSSRPANDLAAAVSQLLTGGPRQL
TH_1479|M.thermoresistible__bu      ------MTEQTPGPASGSFPAKDPEAVCSKPARDLVAATERLLAGGARQL
MAB_3238c|M.abscessus_ATCC_199      ----------------------------MGAATDLVAARAQLLGD-SGRL
MUL_1336|M.ulcerans_Agy99           MNVTKPATQRPKLPSVGRLGLVDALAGAHLAELGWTEHDDQAHVDLLWSL
                                                                     . .    .        :

Mb2942c|M.bovis_AF2122/97           DPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSD
Rv2918c|M.tuberculosis_H37Rv        DPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSD
MMAR_1789|M.marinum_M               DPAELRQAWLDLHESWLIAKAAQIGIADDSGYAIVGVGGLGRRELLPYSD
MAV_3773|M.avium_104                HAAELRHAWLDLHESWLAAKAAQIGIADDSGFALVGIGGLGRHELLPYSD
Mflv_4183|M.gilvum_PYR-GCK          DSAALRDALLDLHDFWLTTKATEIGITATSGFAIVATGGLGRGELLPYSD
Mvan_2180|M.vanbaalenii_PYR-1       DAAALRDALLDLYDFWLTTKASEIGITATSGFAIVATGGLGRGELLPYSD
MSMEG_2427|M.smegmatis_MC2_155      DSAALRDALLDLYEFWLTTKATELGITADSGFAIVATGGLGRGEMLPYSD
TH_1479|M.thermoresistible__bu      DAASLRYALLDLHELWLNTKAAEIGITPVSGFSIVATGGLGRGELVPHSD
MAB_3238c|M.abscessus_ATCC_199      NAAAIREAMTDLNELWLTTKAAEVGITDSSGFAIVALGGLGRREMLPYSD
MUL_1336|M.ulcerans_Agy99           SRAPDADAALKVLVRLAENPDTGWDELNAALLNERSLRGRLFAVLGSSLS
                                      .    :  .:            .    :     .  *     : .  .

Mb2942c|M.bovis_AF2122/97           LDVLLLHDG-----KPADILRPVADRLWYPLWDANIRLDHSVRTVSEALT
Rv2918c|M.tuberculosis_H37Rv        LDVLLLHDG-----KPADILRPVADRLWYPLWDANIRLDHSVRTVSEALT
MMAR_1789|M.marinum_M               LDLVLVHDG-----KPVEELGDVADALWYPLWDANIRLDHSVRTVSDALG
MAV_3773|M.avium_104                LDLMLLHDN-----KSDEVLQRVADALWYPLWDANVRLDHSVRTVSGALG
Mflv_4183|M.gilvum_PYR-GCK          LDLMLLHDN-----MPAEIVGEVAELLWYPLWDANIRLDHSVRTVPEALR
Mvan_2180|M.vanbaalenii_PYR-1       LDLMLLHDN-----MPPEIVSEVAELLWYPLWDANIRLDHSVRTVPEALR
MSMEG_2427|M.smegmatis_MC2_155      LDLMLLHDN-----MPVDVVTEVAEKLWYPLWDANIRLDHSVRTVPEALK
TH_1479|M.thermoresistible__bu      LDLMLLHDG-----MPTELVGRIAEQLWYPLWDANIRIDHSVRTVAEALA
MAB_3238c|M.abscessus_ATCC_199      LDLVLLHDEN----IAPETLSEVADGLWYPLWDANIRLDHSVRTVADTLH
MUL_1336|M.ulcerans_Agy99           LGDHLVANPQSWKLLRGKVALPSHAALLESFVDLAEEVAAAPASAVHRLR
                                    *.  *: :         .        *  .: *   .:  :  :.   * 

Mb2942c|M.bovis_AF2122/97           IANSDLMAALGMLEARHIAGDQ-QLSFALIDGVRRQWRNGIRSRMGELVE
Rv2918c|M.tuberculosis_H37Rv        IANSDLMAALGMLEARHIAGDQ-QLSFALIDGVRRQWRNGIRSRMGELVE
MMAR_1789|M.marinum_M               VAGADMAAALGMLEARHIVGDQ-QLSASLIDGVRRQWRSGIRSRMNELVD
MAV_3773|M.avium_104                VANGDMIAALGMLDARHVAGDA-RLSDELIAGARRQWRSAIRSRMDELVE
Mflv_4183|M.gilvum_PYR-GCK          VAGEDISAGLAMLEARHIAGDA-DLSSLLIGGARRQWRTGIAPRFEELVE
Mvan_2180|M.vanbaalenii_PYR-1       VAGTDISAGLAMLEARHIAGDG-DLSSLLIGGARRQWRTGIASRFDELVE
MSMEG_2427|M.smegmatis_MC2_155      VAGEDISVGLAMLDVRHIAGDA-DLSSLLVGGARRQWRIGIASRFEELVE
TH_1479|M.thermoresistible__bu      VADADIAAGLAMLEARHIAGDA-DLSALVIDGARRHWRTTIASRFDELID
MAB_3238c|M.abscessus_ATCC_199      VAGQEMSAALALLDARHIAGDA-QLSSLMIGGVRQQWRSQIRTRLDELVE
MUL_1336|M.ulcerans_Agy99           ALHRDHVLVLAGLDLAATVEDEPVLSFTVVAAHLADIADAALAAALRLAE
                                        :    *. *:    . *   **  :: .   .      .   .* :

Mb2942c|M.bovis_AF2122/97           MTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHT
Rv2918c|M.tuberculosis_H37Rv        MTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHT
MMAR_1789|M.marinum_M               MTHDRWLRCGRVANRAEPDLKSGRGGLRDVQLLDALAIAQLIDRHGLVTP
MAV_3773|M.avium_104                MTQARWDRCGRIAQRAEPDLKSGRGGLRDVQLLDALGVAQLIDRHGMARP
Mflv_4183|M.gilvum_PYR-GCK          HARARWQRSGEIAHRAEPDLKCGRGGLRDVQLLNALAIAQLADVYPSRSL
Mvan_2180|M.vanbaalenii_PYR-1       HTRARWQRSGEIAHRAEPDLKCGRGGLRDVQLLNALAIAQLADVYPSRSL
MSMEG_2427|M.smegmatis_MC2_155      HAQARWQRSGQIAHRAEPDLKSGRGGLRDVQLLNALAIAQLADVYPSRAL
TH_1479|M.thermoresistible__bu      HTRARWERSGQIAHRAEPDLKCGRGGLRDVQLLNALAIAQLADGYPSSSL
MAB_3238c|M.abscessus_ATCC_199      YTQARWRRSGEIAHRAEPDLKSGRGGLRDVQLLRALAIAQLTDSGLAKSF
MUL_1336|M.ulcerans_Agy99           KTVCRDRTPPRLAVIAVG--KCGARELNYVSDVDVIFVAERADPISIRVA
                                     :  *     .:*  *    * *   *. *. : .: :*:  *       

Mb2942c|M.bovis_AF2122/97           DRPAGSLDGAYRTLLD-----------VRTELHRVSGRGRDHLLAQFADE
Rv2918c|M.tuberculosis_H37Rv        DLPAGSLDGAYRTLLD-----------VRTELHRVSGRGRDHLLAQFADE
MMAR_1789|M.marinum_M               DMPVGSLDAAYLTLLN-----------VRTELHRVSGRGRDLLLAQHADD
MAV_3773|M.avium_104                ESPGGSLDDAHLTLLD-----------VRTELHRVSGRGLDQLLAQYGDE
Mflv_4183|M.gilvum_PYR-GCK          ASPTETLGEANLALLN-----------VRTELHRVAGRGRELLLAQHADE
Mvan_2180|M.vanbaalenii_PYR-1       ASPTETLGEAHLSLLN-----------VRTELHRVAGRGRELLLAQHADE
MSMEG_2427|M.smegmatis_MC2_155      ASPTGTLGGAHLALLN-----------VRTELHRVSGRGRELLLAQHADE
TH_1479|M.thermoresistible__bu      ASPTGTLGDAHLALLD-----------VRTELHRIAGRGRDLLQAQYADE
MAB_3238c|M.abscessus_ATCC_199      DG-------AHSVILD-----------VRTELHRVAGRERDQLLAQFADE
MUL_1336|M.ulcerans_Agy99           GEMMRVASSTFFEVDAGLRPEGRSGELVRTVESHIAYYQRWAKTWEFQAL
                                             :   :             ***   :::         :.   

Mb2942c|M.bovis_AF2122/97           ISAALGFGDRFDLARTLSSAGRTIGYHAEAGLRTAANALPRRGISALVRR
Rv2918c|M.tuberculosis_H37Rv        ISAALGFGDRFDLARTLSSAGRTIGYHAEAGLRTAANALPRRGISALVRR
MMAR_1789|M.marinum_M               ISAALHFGDRFDLARMLSSAGRTIAYHAESGLRTACNALPRRGISALRRR
MAV_3773|M.avium_104                LSAALHIGDRFDLARKLSDASRTIAYHAETGLRTAENALPRRGVSALVRR
Mflv_4183|M.gilvum_PYR-GCK          IGASLRIGDRFDLARTLSDAARTVSYYVDAGIRTAANSLPRRGLAAL-RR
Mvan_2180|M.vanbaalenii_PYR-1       IGAALHIGDRFDLARMLSDAARTVSYYVDAGIRTAANALPRRGLAVL-RR
MSMEG_2427|M.smegmatis_MC2_155      IGAALRIGDRFDLARMLSDAARTVSYYVDSGIRTAANALPRRGFAAL-RR
TH_1479|M.thermoresistible__bu      IAAALRIGDRFDLARLLSDAARTVSYYVDSGLRTAANALPRRGFAAL-RR
MAB_3238c|M.abscessus_ATCC_199      IGAALRIGDRFDLARMLSDAARTISYSVDVGLRAAANSIPRRGISAL-RR
MUL_1336|M.ulcerans_Agy99           LKARAAVGDAELGQRYLAALMPMVWTACERDDFVAEVQAMRRRVEQLVPA
                                    : *   .**     * *:     :    : .  .*     ** .  *   

Mb2942c|M.bovis_AF2122/97           PKR-RPLDEG-----VVEYAGEIVLARDAEPEHDPGLVLRVAAASADTG-
Rv2918c|M.tuberculosis_H37Rv        PKR-RPLDEG-----VVEYAGEIVLARDAEPEHDPGLVLRVAAASADTG-
MMAR_1789|M.marinum_M               PKR-RPLDEG-----VVECANEIVLARDAQPEQDAGLVLRVAAAAAHAG-
MAV_3773|M.avium_104                PKR-RPLDEG-----VVEYAGEIVLARDARPDTDVGLVLRVAAASASTG-
Mflv_4183|M.gilvum_PYR-GCK          PVR-RPLDEG-----VIEFAGEVILARDARPERDPGLILRVAAASATTG-
Mvan_2180|M.vanbaalenii_PYR-1       PVR-RPLDEG-----VIEFNGEVILARDARPERDPGLILRVAAASATTG-
MSMEG_2427|M.smegmatis_MC2_155      PVR-RPLDEG-----VIEFAGEVILARDARPERDPGLVLRVAAASATTG-
TH_1479|M.thermoresistible__bu      PLR-RPLDEG-----VVEYAGEVILARDARPARDPGLILRVAAASATTG-
MAB_3238c|M.abscessus_ATCC_199      TVR-RPIDEG-----VVEHAGEVVLARDARPERDPSLILRVAAASATTG-
MUL_1336|M.ulcerans_Agy99           DIRGRELKLGTGGLRDVEFVAQLLQLVHGRSDESLHVASTVDALSALGEG
                                      * * :. *      :*   :::   ....  .  :   * * :*    

Mb2942c|M.bovis_AF2122/97           ---------LPIGAATLSRLAASVPDLP----TPWPQEALDDLLVVLSAG
Rv2918c|M.tuberculosis_H37Rv        ---------LPIGAATLSRLAASVPDLP----TPWPQEALDDLLVVLSAG
MMAR_1789|M.marinum_M               ---------LPIGAATLRRLADSAAELP----TPWPREVLDDLLVVLLAG
MAV_3773|M.avium_104                ---------LPIGAATLSRLAAAAPEMP----EPWPREALDDLLVLLSAG
Mflv_4183|M.gilvum_PYR-GCK          ---------LPIAGSTLSRLVEAAPELR----TPWPRQALKDLLVMLAAG
Mvan_2180|M.vanbaalenii_PYR-1       ---------LPMAASTLSRLVEAAPELR----TPWPGQALKDLLVMLAAG
MSMEG_2427|M.smegmatis_MC2_155      ---------LPIAVSTLSRLAETAPELR----TPWPSQALKDLLVLLAAG
TH_1479|M.thermoresistible__bu      ---------LPIAASTLSRLAATAPELR----APWPRPALNDLLVLLGAG
MAB_3238c|M.abscessus_ATCC_199      ---------LPIAASTLARLAESAPELR----TPWPREALKDLLVLLESG
MUL_1336|M.ulcerans_Agy99           GYIGREDAANMIASYEFLRLLEHRLQLQRLKRTHLLPEFDDEEAVRWLAR
                                               :.   : **     ::             .:  *   : 

Mb2942c|M.bovis_AF2122/97           PTTVATIEALDRTGLWGRLLPEWEP-IRDLPPRDVAHKWTVDRHVVETAV
Rv2918c|M.tuberculosis_H37Rv        PTTVATIEALDRTGLWGRLLPEWEP-IRDLPPRDVAHKWTVDRHVVETAV
MMAR_1789|M.marinum_M               PTAVVTIEALDRTGLWGRLLPEWGA-IRDLPPRDVAHKWTVDRHLIETAV
MAV_3773|M.avium_104                PTTVATIEALDRTGLWGRLLPEWDA-IRDLPPRDVAHKWTVDRHVIETTV
Mflv_4183|M.gilvum_PYR-GCK          PSAVGTIEALDRTGLWGRLFPEWGA-VRDLPPRDVVHIWTVDRHLVETVS
Mvan_2180|M.vanbaalenii_PYR-1       PSAVATIEALDRTGLWGRLFPEWGA-VRDLPPRDVVHIWTVDRHLVETVS
MSMEG_2427|M.smegmatis_MC2_155      PAAVATIEALDRTGLWGRLFPEWGA-VRDLPPRDVVHIWTVDRHLVETVS
TH_1479|M.thermoresistible__bu      PAAVGTIEALDRTGLWGRLFPEWGA-VRDLPPRDIVHVWTVDRHLTETVA
MAB_3238c|M.abscessus_ATCC_199      RPALATIEALDRTGLWGRLFPEWGP-VRDLPPRDIVHIWTVDRHLVETVV
MUL_1336|M.ulcerans_Agy99           AAHIRPDGRHDAAGMLREELKHQNVRVSRLHAKLFYQPLLESIAPAGLEI
                                     . : .    * :*:  . : .    :  * .: . :    .        

Mb2942c|M.bovis_AF2122/97           HAAPLATRVARPDLLALG------ALLHDIGKG-RGTDHSVLGAELVIPV
Rv2918c|M.tuberculosis_H37Rv        HAAPLATRVARPDLLALG------ALLHDIGKG-RGTDHSVLGAELVIPV
MMAR_1789|M.marinum_M               QAAPLTTQVARPDLLALG------ALLHDIGKG-RGADHSVLGAEMVVAI
MAV_3773|M.avium_104                NAAPLATRVARPDLLALG------ALLHDIGKG-RGVDHSVLGAGLALEI
Mflv_4183|M.gilvum_PYR-GCK          RASAFTTRVSRPDLLLLG------ALVHDIGKG-RGGDHSVIGAELAHQI
Mvan_2180|M.vanbaalenii_PYR-1       RASAFTTRVSRPDLLILG------ALVHDIGKG-RGGDHSVIGAELADQI
MSMEG_2427|M.smegmatis_MC2_155      RASAFTTRVSRPDLLLLG------ALCHDIGKG-RGGDHSVIGAELATQI
TH_1479|M.thermoresistible__bu      QASALTTRVSRPDLLLLG------ALLHDIGKG-RGGDHSVIGAELAAQI
MAB_3238c|M.abscessus_ATCC_199      QASAFTTRVSRPDLLVLG------ALVHDIGKG-RGGDHSVVGADLAVQI
MUL_1336|M.ulcerans_Agy99           AGRGMTSEAAERQLAALGYEGPQTALKHMAALVNHSGRRARVQSVLLPRL
                                     .  :::..:. :*  **      ** *  .   :.  :: : : :   :

Mb2942c|M.bovis_AF2122/97           CTRLGLSP-PDVWTLSKLVRHHLLLPITATRRDLND-PKTIEAVSEALGG
Rv2918c|M.tuberculosis_H37Rv        CTRLGLSP-PDVRTLSKLVRHHLLLPITATRRDLND-PKTIEAVSEALGG
MMAR_1789|M.marinum_M               GQRLGISA-PDIDLLSKLVRHHLLLPVVATRSDLND-PSTITRVSEALGG
MAV_3773|M.avium_104                GPRLGMAP-ADVELLAQLVRHHLLLPVAATRSDLND-PKTIERVSKTLGE
Mflv_4183|M.gilvum_PYR-GCK          GSRLGLWP-SDIKILAQVVRYHLLLPHTATRRDLQD-AATISAVVDALDG
Mvan_2180|M.vanbaalenii_PYR-1       GSRLGLWP-SDIRVLSTLVRHHLLLPHTATRRDLQD-PATIAAVVDALDG
MSMEG_2427|M.smegmatis_MC2_155      GTRLGLWP-SDIDVLSKLVRYHLLLPETATRRDLQD-PKTIAAVVDALGG
TH_1479|M.thermoresistible__bu      GARLGLWP-SDIDILVKLVRHHLLLVRTATRRDLDD-PRTIESVVDALGP
MAB_3238c|M.abscessus_ATCC_199      GTRLGLWP-SDVELLSKIVRYHLLLPNTATRRDLAD-PETIDGVVNTLGG
MUL_1336|M.ulcerans_Agy99           LDWLSYAPDPDGGLLAYRRLSEALAPQSWYLSTLRDKPTVGRRLMHVLGT
                                       *.  . .*   *      . *         * * . .   : ..*. 

Mb2942c|M.bovis_AF2122/97           DPQLLEVLHALSEADS----KATGPGVWSDWKASLVDDLVR-------RC
Rv2918c|M.tuberculosis_H37Rv        DPQLLEVLHALSEADS----KATGPGVWSDWKASLVDDLVR-------RC
MMAR_1789|M.marinum_M               DPQLLEVLRALTEADS----KATGPGVWSDWKASLVDDLVS-------RC
MAV_3773|M.avium_104                DPLLLEVLHALTEADS----KATGPGVWSDWKASLIDDLVR-------RC
Mflv_4183|M.gilvum_PYR-GCK          DPAVLELLHVLAEADS----LATGPGVWGDWKASLLGELVR-------RC
Mvan_2180|M.vanbaalenii_PYR-1       DLVVLELLHVLAEADS----LATGPGVWGDWKASLIGELVR-------RC
MSMEG_2427|M.smegmatis_MC2_155      DMVVLELLDVLAEADS----LATGPGVWGDWKASLIGDLVR-------RC
TH_1479|M.thermoresistible__bu      DPVLLDLLHALVEADS----LATGPGVWGEWKAALIGDLVR-------RC
MAB_3238c|M.abscessus_ATCC_199      DLLLLELLQQLAEADS----LATGPGVWGDWKASLIGELVR-------KC
MUL_1336|M.ulcerans_Agy99           SAFVPDLLMRAPEVIQNYGDSRTGPKLLETEPAAVARALIASAGRYSDPL
                                    .  : ::*    *. .      *** :     *::   *:          

Mb2942c|M.bovis_AF2122/97           RMVMAGESLPQAEPTAP---HYLSLAADHGVHVEIS--------------
Rv2918c|M.tuberculosis_H37Rv        RMVMAGESLPQAEPTAP---HYLSLAADHGVHVEIS--------------
MMAR_1789|M.marinum_M               RLAMAGEPLPRADPEAP---HYVSLSADHGVHVEIA--------------
MAV_3773|M.avium_104                RMVMAGEPLPKVEPAAP---QYLSLAADRGVHVQIK--------------
Mflv_4183|M.gilvum_PYR-GCK          RMVMAGEPLPHPDPVDP---RFISLAGQVGVHVELT--------------
Mvan_2180|M.vanbaalenii_PYR-1       RLVMAGEPLPHPDPVDP---RFVALAGDGGVHVELT--------------
MSMEG_2427|M.smegmatis_MC2_155      RLVMAGEPLPHPDPIDP---RFLEIAADVGVHVELT--------------
TH_1479|M.thermoresistible__bu      RLVMAGEPLPHPDPIDP---QHLSLAARGGVHVDLV--------------
MAB_3238c|M.abscessus_ATCC_199      RLVMRGEQLPEPDPIDP---ELLSLAADGGVQVRLV--------------
MUL_1336|M.ulcerans_Agy99           RAIAAARTLRRRELARIGSADLLGLLEVTEVCRALTSVWVAVLQSALEAM
                                    *    .. * . :         : :     *   :               

Mb2942c|M.bovis_AF2122/97           -----PRDGERI-DAVIVAPDERG----LVSKAAAVLALNSLRVHSASVN
Rv2918c|M.tuberculosis_H37Rv        -----PRDGERI-DAVIVAPDERG----LVSKAAAVLALNSLRVHSASVN
MMAR_1789|M.marinum_M               -----PGESARMYQVVMAAPNKPG----LVSKAAAVLALNSLGVHSAWVN
MAV_3773|M.avium_104                -----PGGGERL-DVVMAAPDQRG----LVSKAAAVLALNSLRIHSASAS
Mflv_4183|M.gilvum_PYR-GCK          -----PTDTPHIYQVTMIAPDSRG----VLSKAAGVMALNSLRVHSASVN
Mvan_2180|M.vanbaalenii_PYR-1       -----PAEHSHIYNVTMIAPDSRG----LLSKTAGVLALNSLRVHSASVN
MSMEG_2427|M.smegmatis_MC2_155      -----PGDGQHIFNVTMIAPDRRG----LLSKAAGVLALNSLRVHSASVN
TH_1479|M.thermoresistible__bu      -----PGDGPHIYQVTLVAPDRRG----LLSKAAGVLALNSLRVHSASVN
MAB_3238c|M.abscessus_ATCC_199      -----PAGSPHMYIVSLIAPDQRG----LLSKAAGVLSLNSLRVFSASVA
MUL_1336|M.ulcerans_Agy99           IRANTPEGGRPLARIAVIGMGRLGGSELSYGSDADVMYVCEPASGVTDAQ
                                         *     :    : . .  *      .. * *: : .     : . 

Mb2942c|M.bovis_AF2122/97           VHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSD-
Rv2918c|M.tuberculosis_H37Rv        VHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSD-
MMAR_1789|M.marinum_M               SHEGVAITQFVVSPLFGTPAAADLLRQQFVGALSGDIDALAMVEKRDSE-
MAV_3773|M.avium_104                THEGFAVVEFVVSPLFGSPPEAGLLRQQFTGALGGDVDVLGTLEKRDSD-
Mflv_4183|M.gilvum_PYR-GCK          GHEGSAINSFVVSPRFGTPPAAELLRQQLILAIDGELDVMGALEKKE---
Mvan_2180|M.vanbaalenii_PYR-1       GHEGAAINTFVVSPRFGSPPAAELLRQQLILAIDGELDVMGALEKKE---
MSMEG_2427|M.smegmatis_MC2_155      SHEGSAINTFVVSPHFGSPPAADLLRQQFVLALDGDLDVIGSLERRERE-
TH_1479|M.thermoresistible__bu      SHHGSAINTFVVSPHFGAPPAANLLRQQLILALDGDLDVLAALERRDHDG
MAB_3238c|M.abscessus_ATCC_199      SHAGSAINTFEVSPRFGSPPAAGLLRQQLISAIDGDTDIIAALDERERE-
MUL_1336|M.ulcerans_Agy99           GVKWSTAVAEQVRAKLGTPSVDPPLEVDANLRPEGRNGPLVRTLASYGAY
                                         :     * . :*:*.    :. :      *  . :          

Mb2942c|M.bovis_AF2122/97           -----------AASLVSARAGDVQAG------------------------
Rv2918c|M.tuberculosis_H37Rv        -----------AASLVSARAGDVQAG------------------------
MMAR_1789|M.marinum_M               -----------ATSNASQRAGEVVAG------------------------
MAV_3773|M.avium_104                -----------AVGAATRRAGEVQVG------------------------
Mflv_4183|M.gilvum_PYR-GCK          -----------AESVATGRAGEVRAA------------------------
Mvan_2180|M.vanbaalenii_PYR-1       -----------AESTATGRAGEIRAA------------------------
MSMEG_2427|M.smegmatis_MC2_155      -----------AAQYPTTRAGEILAA------------------------
TH_1479|M.thermoresistible__bu      --APGSHRPGEPAXXXVGVAAESIAAGLTAFEVGRHRAELIATAGGISYV
MAB_3238c|M.abscessus_ATCC_199      -----------SAQFATGVVGDAAPA------------------------
MUL_1336|M.ulcerans_Agy99           YAQWAQAWEIQALLRAHAVAGDAALG------------------------
                                               .       ..:   .                        

Mb2942c|M.bovis_AF2122/97           ---------VPVTRTAAPP---------RILWLDT-----AAPAKLILEV
Rv2918c|M.tuberculosis_H37Rv        ---------VPVTRTAAPP---------RILWLDT-----AAPAKLILEV
MMAR_1789|M.marinum_M               ---------VPVTRSTAPP---------RILWLDS-----AAPDQLVLEV
MAV_3773|M.avium_104                ---------VPVTRSTAPP---------RILWVDT-----AAADQLIVEV
Mflv_4183|M.gilvum_PYR-GCK          ---------VPINAPTAPP---------KVLWHEP-----SGSGHVVAEI
Mvan_2180|M.vanbaalenii_PYR-1       ---------VPINPPTAPP---------RVLWHEG-----AGAGQVVAEI
MSMEG_2427|M.smegmatis_MC2_155      ---------VPANHVPAPP---------RLLWADG-----SNPGELIVQI
TH_1479|M.thermoresistible__bu      DDSKATNPHAAAASIAAHP---------RVVWIAGGLLKGAAVDELVAEV
MAB_3238c|M.abscessus_ATCC_199      ---------VPTNYAPAPP---------RIRWFEP----AGNADQQIVEI
MUL_1336|M.ulcerans_Agy99           -----QRFLLLVDHTRYPPDGVSAEAVHEIRRIKARVESERLPRGADPNT
                                                      *         .:                  : 

Mb2942c|M.bovis_AF2122/97           RAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST-----------
Rv2918c|M.tuberculosis_H37Rv        RAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST-----------
MMAR_1789|M.marinum_M               RSMDRPGLLA-----LLTRALERAGADIVWAKVNTFGST-----------
MAV_3773|M.avium_104                RAMDRLGLLA-----LLTRALERAGTDIVWAKVNTFGST-----------
Mflv_4183|M.gilvum_PYR-GCK          RATDRTGLLA-----VLTRVFERAGVDIAWAKVTTMGSS-----------
Mvan_2180|M.vanbaalenii_PYR-1       RATDRAGLLA-----VLTRVLERAGVDIAWAKVTTLGSS-----------
MSMEG_2427|M.smegmatis_MC2_155      RTIDRAGLLA-----RLTAVFERDGVDIAWAKVTTLGSS-----------
TH_1479|M.thermoresistible__bu      ADRLAGXXLIGRDREIIAQALSRHAPEVPVVSVVTGDDSGMQATAGAPVN
MAB_3238c|M.abscessus_ATCC_199      RTSDAPGLLA-----RITATLERHGVDIAWAKVNTLGSS-----------
MUL_1336|M.ulcerans_Agy99           HTKLGRGGLADIEWTVQLLQLQNAHEIEALHNTSTLESLDAIAEAKLVAE
                                            *           :.         .. *  .            

Mb2942c|M.bovis_AF2122/97           ----AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVGD-
Rv2918c|M.tuberculosis_H37Rv        ----AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVGD-
MMAR_1789|M.marinum_M               ----AADVFCVTVSAGLEEPQARAA-MEQQLSAVLGGSADVLLDEPVGD-
MAV_3773|M.avium_104                ----AADAFCVTA-GDAG---ARDA-VEQSLLTVLGGPAVEVLEEPVGD-
Mflv_4183|M.gilvum_PYR-GCK          ----VIDVFGIVLPAG-EDAVRES--LEKQLLAVLPAPPQPKPVREEAS-
Mvan_2180|M.vanbaalenii_PYR-1       ----VVDAFGIVLPAD-GAAARQN--LERELFAVLPAPP-AKPAEVEAS-
MSMEG_2427|M.smegmatis_MC2_155      ----VVDAFGITTADGRTEQVRQE--LERDLYAVLPTPPPAKPAEQAS--
TH_1479|M.thermoresistible__bu      AVTRVVEATEPIGPAVMTAAVAAARALASPGDTVLLAPAGASFDQFSGYA
MAB_3238c|M.abscessus_ATCC_199      ----VVDTFCLSTGPE-QAVLEAA--IASVLPAVAPQPKKAAAS------
MUL_1336|M.ulcerans_Agy99           DEVKLLRQAWLTATRARNALVLVRGKPTDQLPGPGRQLNAVAVAAGWHND
                                                                                      

Mb2942c|M.bovis_AF2122/97           --------------------------
Rv2918c|M.tuberculosis_H37Rv        --------------------------
MMAR_1789|M.marinum_M               --------------------------
MAV_3773|M.avium_104                --------------------------
Mflv_4183|M.gilvum_PYR-GCK          --------------------------
Mvan_2180|M.vanbaalenii_PYR-1       --------------------------
MSMEG_2427|M.smegmatis_MC2_155      --------------------------
TH_1479|M.thermoresistible__bu      DRGDAFAAAVRAAIR-----------
MAB_3238c|M.abscessus_ATCC_199      --------------------------
MUL_1336|M.ulcerans_Agy99           DGGEFLDNYLRVTRRAKAVVRKVFGS