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MEAESPCAASDLAVARRELLSGNHRELDPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRR ELLPYSDLDVLLLHDGKPADILRPVADRLWYPLWDANIRLDHSVRTVSEALTIANSDLMAALGMLEARHI AGDQQLSFALIDGVRRQWRNGIRSRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALA QLIDRHGIGHTDRPAGSLDGAYRTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSA GRTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARDAEPEHDPGLVLRVAAASA DTGLPIGAATLSRLAASVPDLPTPWPQEALDDLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLP PRDVAHKWTVDRHVVETAVHAAPLATRVARPDLLALGALLHDIGKGRGTDHSVLGAELVIPVCTRLGLSP PDVWTLSKLVRHHLLLPITATRRDLNDPKTIEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKAS LVDDLVRRCRMVMAGESLPQAEPTAPHYLSLAADHGVHVEISPRDGERIDAVIVAPDERGLVSKAAAVLA LNSLRVHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSDAASLVSARA GDVQAGVPVTRTAAPPRILWLDTAAPAKLILEVRAMDRAGLLALLAGALEGAGAGIVWAKVNTFGSTAAD VFCVTVPAELDARAAVEQHLLEVLGASVDVVVDEPVGD
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2942c | glnD | - | 100% (808) | PII uridylyl-transferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4183 | - | 0.0 | 62.81% (796) | PII uridylyl-transferase |
M. tuberculosis H37Rv | Rv2918c | glnD | 0.0 | 99.75% (808) | PII uridylyl-transferase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_3238c | - | 0.0 | 61.74% (792) | PII uridylyl-transferase |
M. marinum M | MMAR_1789 | glnD | 0.0 | 77.71% (812) | uridylyltransferase GlnD |
M. avium 104 | MAV_3773 | glnD | 0.0 | 75.90% (805) | PII uridylyl-transferase |
M. smegmatis MC2 155 | MSMEG_2427 | glnD | 0.0 | 65.25% (774) | PII uridylyl-transferase |
M. thermoresistible (build 8) | TH_1479 | glnD | 0.0 | 66.19% (695) | PROBABLE |
M. ulcerans Agy99 | MUL_1336 | glnE | 9e-05 | 25.71% (315) | glutamate-ammonia-ligase adenylyltransferase GlnE |
M. vanbaalenii PYR-1 | Mvan_2180 | - | 0.0 | 63.54% (790) | PII uridylyl-transferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2942c|M.bovis_AF2122/97 ------MEAE-----------------SPCAASDLAVARRELLSGNHREL Rv2918c|M.tuberculosis_H37Rv ------MEAE-----------------SPCAASDLAVARRELLSGNHREL MMAR_1789|M.marinum_M ------MEPG-----------------SVRAASDLAAARRQLLSDDHRDM MAV_3773|M.avium_104 ------MTPTGP---------DPSGHQNACGAVDLAASRRQLLSEGG-KL Mflv_4183|M.gilvum_PYR-GCK ------MKDSTSKPAAGASRWERPAAVSSRPATDLVAAAEQLLAGGARPL Mvan_2180|M.vanbaalenii_PYR-1 ------MKEQKSQPAAGAPRWERPAAGSLRPATDLVAAADQLLSG-SRQL MSMEG_2427|M.smegmatis_MC2_155 ------MAEHKTQSAG--ASHKGAPAGSSRPANDLAAAVSQLLTGGPRQL TH_1479|M.thermoresistible__bu ------MTEQTPGPASGSFPAKDPEAVCSKPARDLVAATERLLAGGARQL MAB_3238c|M.abscessus_ATCC_199 ----------------------------MGAATDLVAARAQLLGD-SGRL MUL_1336|M.ulcerans_Agy99 MNVTKPATQRPKLPSVGRLGLVDALAGAHLAELGWTEHDDQAHVDLLWSL . . . : Mb2942c|M.bovis_AF2122/97 DPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSD Rv2918c|M.tuberculosis_H37Rv DPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSD MMAR_1789|M.marinum_M DPAELRQAWLDLHESWLIAKAAQIGIADDSGYAIVGVGGLGRRELLPYSD MAV_3773|M.avium_104 HAAELRHAWLDLHESWLAAKAAQIGIADDSGFALVGIGGLGRHELLPYSD Mflv_4183|M.gilvum_PYR-GCK DSAALRDALLDLHDFWLTTKATEIGITATSGFAIVATGGLGRGELLPYSD Mvan_2180|M.vanbaalenii_PYR-1 DAAALRDALLDLYDFWLTTKASEIGITATSGFAIVATGGLGRGELLPYSD MSMEG_2427|M.smegmatis_MC2_155 DSAALRDALLDLYEFWLTTKATELGITADSGFAIVATGGLGRGEMLPYSD TH_1479|M.thermoresistible__bu DAASLRYALLDLHELWLNTKAAEIGITPVSGFSIVATGGLGRGELVPHSD MAB_3238c|M.abscessus_ATCC_199 NAAAIREAMTDLNELWLTTKAAEVGITDSSGFAIVALGGLGRREMLPYSD MUL_1336|M.ulcerans_Agy99 SRAPDADAALKVLVRLAENPDTGWDELNAALLNERSLRGRLFAVLGSSLS . : .: . : . * : . . Mb2942c|M.bovis_AF2122/97 LDVLLLHDG-----KPADILRPVADRLWYPLWDANIRLDHSVRTVSEALT Rv2918c|M.tuberculosis_H37Rv LDVLLLHDG-----KPADILRPVADRLWYPLWDANIRLDHSVRTVSEALT MMAR_1789|M.marinum_M LDLVLVHDG-----KPVEELGDVADALWYPLWDANIRLDHSVRTVSDALG MAV_3773|M.avium_104 LDLMLLHDN-----KSDEVLQRVADALWYPLWDANVRLDHSVRTVSGALG Mflv_4183|M.gilvum_PYR-GCK LDLMLLHDN-----MPAEIVGEVAELLWYPLWDANIRLDHSVRTVPEALR Mvan_2180|M.vanbaalenii_PYR-1 LDLMLLHDN-----MPPEIVSEVAELLWYPLWDANIRLDHSVRTVPEALR MSMEG_2427|M.smegmatis_MC2_155 LDLMLLHDN-----MPVDVVTEVAEKLWYPLWDANIRLDHSVRTVPEALK TH_1479|M.thermoresistible__bu LDLMLLHDG-----MPTELVGRIAEQLWYPLWDANIRIDHSVRTVAEALA MAB_3238c|M.abscessus_ATCC_199 LDLVLLHDEN----IAPETLSEVADGLWYPLWDANIRLDHSVRTVADTLH MUL_1336|M.ulcerans_Agy99 LGDHLVANPQSWKLLRGKVALPSHAALLESFVDLAEEVAAAPASAVHRLR *. *: : . * .: * .: : :. * Mb2942c|M.bovis_AF2122/97 IANSDLMAALGMLEARHIAGDQ-QLSFALIDGVRRQWRNGIRSRMGELVE Rv2918c|M.tuberculosis_H37Rv IANSDLMAALGMLEARHIAGDQ-QLSFALIDGVRRQWRNGIRSRMGELVE MMAR_1789|M.marinum_M VAGADMAAALGMLEARHIVGDQ-QLSASLIDGVRRQWRSGIRSRMNELVD MAV_3773|M.avium_104 VANGDMIAALGMLDARHVAGDA-RLSDELIAGARRQWRSAIRSRMDELVE Mflv_4183|M.gilvum_PYR-GCK VAGEDISAGLAMLEARHIAGDA-DLSSLLIGGARRQWRTGIAPRFEELVE Mvan_2180|M.vanbaalenii_PYR-1 VAGTDISAGLAMLEARHIAGDG-DLSSLLIGGARRQWRTGIASRFDELVE MSMEG_2427|M.smegmatis_MC2_155 VAGEDISVGLAMLDVRHIAGDA-DLSSLLVGGARRQWRIGIASRFEELVE TH_1479|M.thermoresistible__bu VADADIAAGLAMLEARHIAGDA-DLSALVIDGARRHWRTTIASRFDELID MAB_3238c|M.abscessus_ATCC_199 VAGQEMSAALALLDARHIAGDA-QLSSLMIGGVRQQWRSQIRTRLDELVE MUL_1336|M.ulcerans_Agy99 ALHRDHVLVLAGLDLAATVEDEPVLSFTVVAAHLADIADAALAAALRLAE : *. *: . * ** :: . . . .* : Mb2942c|M.bovis_AF2122/97 MTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHT Rv2918c|M.tuberculosis_H37Rv MTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHT MMAR_1789|M.marinum_M MTHDRWLRCGRVANRAEPDLKSGRGGLRDVQLLDALAIAQLIDRHGLVTP MAV_3773|M.avium_104 MTQARWDRCGRIAQRAEPDLKSGRGGLRDVQLLDALGVAQLIDRHGMARP Mflv_4183|M.gilvum_PYR-GCK HARARWQRSGEIAHRAEPDLKCGRGGLRDVQLLNALAIAQLADVYPSRSL Mvan_2180|M.vanbaalenii_PYR-1 HTRARWQRSGEIAHRAEPDLKCGRGGLRDVQLLNALAIAQLADVYPSRSL MSMEG_2427|M.smegmatis_MC2_155 HAQARWQRSGQIAHRAEPDLKSGRGGLRDVQLLNALAIAQLADVYPSRAL TH_1479|M.thermoresistible__bu HTRARWERSGQIAHRAEPDLKCGRGGLRDVQLLNALAIAQLADGYPSSSL MAB_3238c|M.abscessus_ATCC_199 YTQARWRRSGEIAHRAEPDLKSGRGGLRDVQLLRALAIAQLTDSGLAKSF MUL_1336|M.ulcerans_Agy99 KTVCRDRTPPRLAVIAVG--KCGARELNYVSDVDVIFVAERADPISIRVA : * .:* * * * *. *. : .: :*: * Mb2942c|M.bovis_AF2122/97 DRPAGSLDGAYRTLLD-----------VRTELHRVSGRGRDHLLAQFADE Rv2918c|M.tuberculosis_H37Rv DLPAGSLDGAYRTLLD-----------VRTELHRVSGRGRDHLLAQFADE MMAR_1789|M.marinum_M DMPVGSLDAAYLTLLN-----------VRTELHRVSGRGRDLLLAQHADD MAV_3773|M.avium_104 ESPGGSLDDAHLTLLD-----------VRTELHRVSGRGLDQLLAQYGDE Mflv_4183|M.gilvum_PYR-GCK ASPTETLGEANLALLN-----------VRTELHRVAGRGRELLLAQHADE Mvan_2180|M.vanbaalenii_PYR-1 ASPTETLGEAHLSLLN-----------VRTELHRVAGRGRELLLAQHADE MSMEG_2427|M.smegmatis_MC2_155 ASPTGTLGGAHLALLN-----------VRTELHRVSGRGRELLLAQHADE TH_1479|M.thermoresistible__bu ASPTGTLGDAHLALLD-----------VRTELHRIAGRGRDLLQAQYADE MAB_3238c|M.abscessus_ATCC_199 DG-------AHSVILD-----------VRTELHRVAGRERDQLLAQFADE MUL_1336|M.ulcerans_Agy99 GEMMRVASSTFFEVDAGLRPEGRSGELVRTVESHIAYYQRWAKTWEFQAL : : *** ::: :. Mb2942c|M.bovis_AF2122/97 ISAALGFGDRFDLARTLSSAGRTIGYHAEAGLRTAANALPRRGISALVRR Rv2918c|M.tuberculosis_H37Rv ISAALGFGDRFDLARTLSSAGRTIGYHAEAGLRTAANALPRRGISALVRR MMAR_1789|M.marinum_M ISAALHFGDRFDLARMLSSAGRTIAYHAESGLRTACNALPRRGISALRRR MAV_3773|M.avium_104 LSAALHIGDRFDLARKLSDASRTIAYHAETGLRTAENALPRRGVSALVRR Mflv_4183|M.gilvum_PYR-GCK IGASLRIGDRFDLARTLSDAARTVSYYVDAGIRTAANSLPRRGLAAL-RR Mvan_2180|M.vanbaalenii_PYR-1 IGAALHIGDRFDLARMLSDAARTVSYYVDAGIRTAANALPRRGLAVL-RR MSMEG_2427|M.smegmatis_MC2_155 IGAALRIGDRFDLARMLSDAARTVSYYVDSGIRTAANALPRRGFAAL-RR TH_1479|M.thermoresistible__bu IAAALRIGDRFDLARLLSDAARTVSYYVDSGLRTAANALPRRGFAAL-RR MAB_3238c|M.abscessus_ATCC_199 IGAALRIGDRFDLARMLSDAARTISYSVDVGLRAAANSIPRRGISAL-RR MUL_1336|M.ulcerans_Agy99 LKARAAVGDAELGQRYLAALMPMVWTACERDDFVAEVQAMRRRVEQLVPA : * .** * *: : : . .* ** . * Mb2942c|M.bovis_AF2122/97 PKR-RPLDEG-----VVEYAGEIVLARDAEPEHDPGLVLRVAAASADTG- Rv2918c|M.tuberculosis_H37Rv PKR-RPLDEG-----VVEYAGEIVLARDAEPEHDPGLVLRVAAASADTG- MMAR_1789|M.marinum_M PKR-RPLDEG-----VVECANEIVLARDAQPEQDAGLVLRVAAAAAHAG- MAV_3773|M.avium_104 PKR-RPLDEG-----VVEYAGEIVLARDARPDTDVGLVLRVAAASASTG- Mflv_4183|M.gilvum_PYR-GCK PVR-RPLDEG-----VIEFAGEVILARDARPERDPGLILRVAAASATTG- Mvan_2180|M.vanbaalenii_PYR-1 PVR-RPLDEG-----VIEFNGEVILARDARPERDPGLILRVAAASATTG- MSMEG_2427|M.smegmatis_MC2_155 PVR-RPLDEG-----VIEFAGEVILARDARPERDPGLVLRVAAASATTG- TH_1479|M.thermoresistible__bu PLR-RPLDEG-----VVEYAGEVILARDARPARDPGLILRVAAASATTG- MAB_3238c|M.abscessus_ATCC_199 TVR-RPIDEG-----VVEHAGEVVLARDARPERDPSLILRVAAASATTG- MUL_1336|M.ulcerans_Agy99 DIRGRELKLGTGGLRDVEFVAQLLQLVHGRSDESLHVASTVDALSALGEG * * :. * :* ::: .... . : * * :* Mb2942c|M.bovis_AF2122/97 ---------LPIGAATLSRLAASVPDLP----TPWPQEALDDLLVVLSAG Rv2918c|M.tuberculosis_H37Rv ---------LPIGAATLSRLAASVPDLP----TPWPQEALDDLLVVLSAG MMAR_1789|M.marinum_M ---------LPIGAATLRRLADSAAELP----TPWPREVLDDLLVVLLAG MAV_3773|M.avium_104 ---------LPIGAATLSRLAAAAPEMP----EPWPREALDDLLVLLSAG Mflv_4183|M.gilvum_PYR-GCK ---------LPIAGSTLSRLVEAAPELR----TPWPRQALKDLLVMLAAG Mvan_2180|M.vanbaalenii_PYR-1 ---------LPMAASTLSRLVEAAPELR----TPWPGQALKDLLVMLAAG MSMEG_2427|M.smegmatis_MC2_155 ---------LPIAVSTLSRLAETAPELR----TPWPSQALKDLLVLLAAG TH_1479|M.thermoresistible__bu ---------LPIAASTLSRLAATAPELR----APWPRPALNDLLVLLGAG MAB_3238c|M.abscessus_ATCC_199 ---------LPIAASTLARLAESAPELR----TPWPREALKDLLVLLESG MUL_1336|M.ulcerans_Agy99 GYIGREDAANMIASYEFLRLLEHRLQLQRLKRTHLLPEFDDEEAVRWLAR :. : ** :: .: * : Mb2942c|M.bovis_AF2122/97 PTTVATIEALDRTGLWGRLLPEWEP-IRDLPPRDVAHKWTVDRHVVETAV Rv2918c|M.tuberculosis_H37Rv PTTVATIEALDRTGLWGRLLPEWEP-IRDLPPRDVAHKWTVDRHVVETAV MMAR_1789|M.marinum_M PTAVVTIEALDRTGLWGRLLPEWGA-IRDLPPRDVAHKWTVDRHLIETAV MAV_3773|M.avium_104 PTTVATIEALDRTGLWGRLLPEWDA-IRDLPPRDVAHKWTVDRHVIETTV Mflv_4183|M.gilvum_PYR-GCK PSAVGTIEALDRTGLWGRLFPEWGA-VRDLPPRDVVHIWTVDRHLVETVS Mvan_2180|M.vanbaalenii_PYR-1 PSAVATIEALDRTGLWGRLFPEWGA-VRDLPPRDVVHIWTVDRHLVETVS MSMEG_2427|M.smegmatis_MC2_155 PAAVATIEALDRTGLWGRLFPEWGA-VRDLPPRDVVHIWTVDRHLVETVS TH_1479|M.thermoresistible__bu PAAVGTIEALDRTGLWGRLFPEWGA-VRDLPPRDIVHVWTVDRHLTETVA MAB_3238c|M.abscessus_ATCC_199 RPALATIEALDRTGLWGRLFPEWGP-VRDLPPRDIVHIWTVDRHLVETVV MUL_1336|M.ulcerans_Agy99 AAHIRPDGRHDAAGMLREELKHQNVRVSRLHAKLFYQPLLESIAPAGLEI . : . * :*: . : . : * .: . : . Mb2942c|M.bovis_AF2122/97 HAAPLATRVARPDLLALG------ALLHDIGKG-RGTDHSVLGAELVIPV Rv2918c|M.tuberculosis_H37Rv HAAPLATRVARPDLLALG------ALLHDIGKG-RGTDHSVLGAELVIPV MMAR_1789|M.marinum_M QAAPLTTQVARPDLLALG------ALLHDIGKG-RGADHSVLGAEMVVAI MAV_3773|M.avium_104 NAAPLATRVARPDLLALG------ALLHDIGKG-RGVDHSVLGAGLALEI Mflv_4183|M.gilvum_PYR-GCK RASAFTTRVSRPDLLLLG------ALVHDIGKG-RGGDHSVIGAELAHQI Mvan_2180|M.vanbaalenii_PYR-1 RASAFTTRVSRPDLLILG------ALVHDIGKG-RGGDHSVIGAELADQI MSMEG_2427|M.smegmatis_MC2_155 RASAFTTRVSRPDLLLLG------ALCHDIGKG-RGGDHSVIGAELATQI TH_1479|M.thermoresistible__bu QASALTTRVSRPDLLLLG------ALLHDIGKG-RGGDHSVIGAELAAQI MAB_3238c|M.abscessus_ATCC_199 QASAFTTRVSRPDLLVLG------ALVHDIGKG-RGGDHSVVGADLAVQI MUL_1336|M.ulcerans_Agy99 AGRGMTSEAAERQLAALGYEGPQTALKHMAALVNHSGRRARVQSVLLPRL . :::..:. :* ** ** * . :. :: : : : : Mb2942c|M.bovis_AF2122/97 CTRLGLSP-PDVWTLSKLVRHHLLLPITATRRDLND-PKTIEAVSEALGG Rv2918c|M.tuberculosis_H37Rv CTRLGLSP-PDVRTLSKLVRHHLLLPITATRRDLND-PKTIEAVSEALGG MMAR_1789|M.marinum_M GQRLGISA-PDIDLLSKLVRHHLLLPVVATRSDLND-PSTITRVSEALGG MAV_3773|M.avium_104 GPRLGMAP-ADVELLAQLVRHHLLLPVAATRSDLND-PKTIERVSKTLGE Mflv_4183|M.gilvum_PYR-GCK GSRLGLWP-SDIKILAQVVRYHLLLPHTATRRDLQD-AATISAVVDALDG Mvan_2180|M.vanbaalenii_PYR-1 GSRLGLWP-SDIRVLSTLVRHHLLLPHTATRRDLQD-PATIAAVVDALDG MSMEG_2427|M.smegmatis_MC2_155 GTRLGLWP-SDIDVLSKLVRYHLLLPETATRRDLQD-PKTIAAVVDALGG TH_1479|M.thermoresistible__bu GARLGLWP-SDIDILVKLVRHHLLLVRTATRRDLDD-PRTIESVVDALGP MAB_3238c|M.abscessus_ATCC_199 GTRLGLWP-SDVELLSKIVRYHLLLPNTATRRDLAD-PETIDGVVNTLGG MUL_1336|M.ulcerans_Agy99 LDWLSYAPDPDGGLLAYRRLSEALAPQSWYLSTLRDKPTVGRRLMHVLGT *. . .* * . * * * . . : ..*. Mb2942c|M.bovis_AF2122/97 DPQLLEVLHALSEADS----KATGPGVWSDWKASLVDDLVR-------RC Rv2918c|M.tuberculosis_H37Rv DPQLLEVLHALSEADS----KATGPGVWSDWKASLVDDLVR-------RC MMAR_1789|M.marinum_M DPQLLEVLRALTEADS----KATGPGVWSDWKASLVDDLVS-------RC MAV_3773|M.avium_104 DPLLLEVLHALTEADS----KATGPGVWSDWKASLIDDLVR-------RC Mflv_4183|M.gilvum_PYR-GCK DPAVLELLHVLAEADS----LATGPGVWGDWKASLLGELVR-------RC Mvan_2180|M.vanbaalenii_PYR-1 DLVVLELLHVLAEADS----LATGPGVWGDWKASLIGELVR-------RC MSMEG_2427|M.smegmatis_MC2_155 DMVVLELLDVLAEADS----LATGPGVWGDWKASLIGDLVR-------RC TH_1479|M.thermoresistible__bu DPVLLDLLHALVEADS----LATGPGVWGEWKAALIGDLVR-------RC MAB_3238c|M.abscessus_ATCC_199 DLLLLELLQQLAEADS----LATGPGVWGDWKASLIGELVR-------KC MUL_1336|M.ulcerans_Agy99 SAFVPDLLMRAPEVIQNYGDSRTGPKLLETEPAAVARALIASAGRYSDPL . : ::* *. . *** : *:: *: Mb2942c|M.bovis_AF2122/97 RMVMAGESLPQAEPTAP---HYLSLAADHGVHVEIS-------------- Rv2918c|M.tuberculosis_H37Rv RMVMAGESLPQAEPTAP---HYLSLAADHGVHVEIS-------------- MMAR_1789|M.marinum_M RLAMAGEPLPRADPEAP---HYVSLSADHGVHVEIA-------------- MAV_3773|M.avium_104 RMVMAGEPLPKVEPAAP---QYLSLAADRGVHVQIK-------------- Mflv_4183|M.gilvum_PYR-GCK RMVMAGEPLPHPDPVDP---RFISLAGQVGVHVELT-------------- Mvan_2180|M.vanbaalenii_PYR-1 RLVMAGEPLPHPDPVDP---RFVALAGDGGVHVELT-------------- MSMEG_2427|M.smegmatis_MC2_155 RLVMAGEPLPHPDPIDP---RFLEIAADVGVHVELT-------------- TH_1479|M.thermoresistible__bu RLVMAGEPLPHPDPIDP---QHLSLAARGGVHVDLV-------------- MAB_3238c|M.abscessus_ATCC_199 RLVMRGEQLPEPDPIDP---ELLSLAADGGVQVRLV-------------- MUL_1336|M.ulcerans_Agy99 RAIAAARTLRRRELARIGSADLLGLLEVTEVCRALTSVWVAVLQSALEAM * .. * . : : : * : Mb2942c|M.bovis_AF2122/97 -----PRDGERI-DAVIVAPDERG----LVSKAAAVLALNSLRVHSASVN Rv2918c|M.tuberculosis_H37Rv -----PRDGERI-DAVIVAPDERG----LVSKAAAVLALNSLRVHSASVN MMAR_1789|M.marinum_M -----PGESARMYQVVMAAPNKPG----LVSKAAAVLALNSLGVHSAWVN MAV_3773|M.avium_104 -----PGGGERL-DVVMAAPDQRG----LVSKAAAVLALNSLRIHSASAS Mflv_4183|M.gilvum_PYR-GCK -----PTDTPHIYQVTMIAPDSRG----VLSKAAGVMALNSLRVHSASVN Mvan_2180|M.vanbaalenii_PYR-1 -----PAEHSHIYNVTMIAPDSRG----LLSKTAGVLALNSLRVHSASVN MSMEG_2427|M.smegmatis_MC2_155 -----PGDGQHIFNVTMIAPDRRG----LLSKAAGVLALNSLRVHSASVN TH_1479|M.thermoresistible__bu -----PGDGPHIYQVTLVAPDRRG----LLSKAAGVLALNSLRVHSASVN MAB_3238c|M.abscessus_ATCC_199 -----PAGSPHMYIVSLIAPDQRG----LLSKAAGVLSLNSLRVFSASVA MUL_1336|M.ulcerans_Agy99 IRANTPEGGRPLARIAVIGMGRLGGSELSYGSDADVMYVCEPASGVTDAQ * : : . . * .. * *: : . : . Mb2942c|M.bovis_AF2122/97 VHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSD- Rv2918c|M.tuberculosis_H37Rv VHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSD- MMAR_1789|M.marinum_M SHEGVAITQFVVSPLFGTPAAADLLRQQFVGALSGDIDALAMVEKRDSE- MAV_3773|M.avium_104 THEGFAVVEFVVSPLFGSPPEAGLLRQQFTGALGGDVDVLGTLEKRDSD- Mflv_4183|M.gilvum_PYR-GCK GHEGSAINSFVVSPRFGTPPAAELLRQQLILAIDGELDVMGALEKKE--- Mvan_2180|M.vanbaalenii_PYR-1 GHEGAAINTFVVSPRFGSPPAAELLRQQLILAIDGELDVMGALEKKE--- MSMEG_2427|M.smegmatis_MC2_155 SHEGSAINTFVVSPHFGSPPAADLLRQQFVLALDGDLDVIGSLERRERE- TH_1479|M.thermoresistible__bu SHHGSAINTFVVSPHFGAPPAANLLRQQLILALDGDLDVLAALERRDHDG MAB_3238c|M.abscessus_ATCC_199 SHAGSAINTFEVSPRFGSPPAAGLLRQQLISAIDGDTDIIAALDERERE- MUL_1336|M.ulcerans_Agy99 GVKWSTAVAEQVRAKLGTPSVDPPLEVDANLRPEGRNGPLVRTLASYGAY : * . :*:*. :. : * . : Mb2942c|M.bovis_AF2122/97 -----------AASLVSARAGDVQAG------------------------ Rv2918c|M.tuberculosis_H37Rv -----------AASLVSARAGDVQAG------------------------ MMAR_1789|M.marinum_M -----------ATSNASQRAGEVVAG------------------------ MAV_3773|M.avium_104 -----------AVGAATRRAGEVQVG------------------------ Mflv_4183|M.gilvum_PYR-GCK -----------AESVATGRAGEVRAA------------------------ Mvan_2180|M.vanbaalenii_PYR-1 -----------AESTATGRAGEIRAA------------------------ MSMEG_2427|M.smegmatis_MC2_155 -----------AAQYPTTRAGEILAA------------------------ TH_1479|M.thermoresistible__bu --APGSHRPGEPAXXXVGVAAESIAAGLTAFEVGRHRAELIATAGGISYV MAB_3238c|M.abscessus_ATCC_199 -----------SAQFATGVVGDAAPA------------------------ MUL_1336|M.ulcerans_Agy99 YAQWAQAWEIQALLRAHAVAGDAALG------------------------ . ..: . Mb2942c|M.bovis_AF2122/97 ---------VPVTRTAAPP---------RILWLDT-----AAPAKLILEV Rv2918c|M.tuberculosis_H37Rv ---------VPVTRTAAPP---------RILWLDT-----AAPAKLILEV MMAR_1789|M.marinum_M ---------VPVTRSTAPP---------RILWLDS-----AAPDQLVLEV MAV_3773|M.avium_104 ---------VPVTRSTAPP---------RILWVDT-----AAADQLIVEV Mflv_4183|M.gilvum_PYR-GCK ---------VPINAPTAPP---------KVLWHEP-----SGSGHVVAEI Mvan_2180|M.vanbaalenii_PYR-1 ---------VPINPPTAPP---------RVLWHEG-----AGAGQVVAEI MSMEG_2427|M.smegmatis_MC2_155 ---------VPANHVPAPP---------RLLWADG-----SNPGELIVQI TH_1479|M.thermoresistible__bu DDSKATNPHAAAASIAAHP---------RVVWIAGGLLKGAAVDELVAEV MAB_3238c|M.abscessus_ATCC_199 ---------VPTNYAPAPP---------RIRWFEP----AGNADQQIVEI MUL_1336|M.ulcerans_Agy99 -----QRFLLLVDHTRYPPDGVSAEAVHEIRRIKARVESERLPRGADPNT * .: : Mb2942c|M.bovis_AF2122/97 RAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST----------- Rv2918c|M.tuberculosis_H37Rv RAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST----------- MMAR_1789|M.marinum_M RSMDRPGLLA-----LLTRALERAGADIVWAKVNTFGST----------- MAV_3773|M.avium_104 RAMDRLGLLA-----LLTRALERAGTDIVWAKVNTFGST----------- Mflv_4183|M.gilvum_PYR-GCK RATDRTGLLA-----VLTRVFERAGVDIAWAKVTTMGSS----------- Mvan_2180|M.vanbaalenii_PYR-1 RATDRAGLLA-----VLTRVLERAGVDIAWAKVTTLGSS----------- MSMEG_2427|M.smegmatis_MC2_155 RTIDRAGLLA-----RLTAVFERDGVDIAWAKVTTLGSS----------- TH_1479|M.thermoresistible__bu ADRLAGXXLIGRDREIIAQALSRHAPEVPVVSVVTGDDSGMQATAGAPVN MAB_3238c|M.abscessus_ATCC_199 RTSDAPGLLA-----RITATLERHGVDIAWAKVNTLGSS----------- MUL_1336|M.ulcerans_Agy99 HTKLGRGGLADIEWTVQLLQLQNAHEIEALHNTSTLESLDAIAEAKLVAE * :. .. * . Mb2942c|M.bovis_AF2122/97 ----AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVGD- Rv2918c|M.tuberculosis_H37Rv ----AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVGD- MMAR_1789|M.marinum_M ----AADVFCVTVSAGLEEPQARAA-MEQQLSAVLGGSADVLLDEPVGD- MAV_3773|M.avium_104 ----AADAFCVTA-GDAG---ARDA-VEQSLLTVLGGPAVEVLEEPVGD- Mflv_4183|M.gilvum_PYR-GCK ----VIDVFGIVLPAG-EDAVRES--LEKQLLAVLPAPPQPKPVREEAS- Mvan_2180|M.vanbaalenii_PYR-1 ----VVDAFGIVLPAD-GAAARQN--LERELFAVLPAPP-AKPAEVEAS- MSMEG_2427|M.smegmatis_MC2_155 ----VVDAFGITTADGRTEQVRQE--LERDLYAVLPTPPPAKPAEQAS-- TH_1479|M.thermoresistible__bu AVTRVVEATEPIGPAVMTAAVAAARALASPGDTVLLAPAGASFDQFSGYA MAB_3238c|M.abscessus_ATCC_199 ----VVDTFCLSTGPE-QAVLEAA--IASVLPAVAPQPKKAAAS------ MUL_1336|M.ulcerans_Agy99 DEVKLLRQAWLTATRARNALVLVRGKPTDQLPGPGRQLNAVAVAAGWHND Mb2942c|M.bovis_AF2122/97 -------------------------- Rv2918c|M.tuberculosis_H37Rv -------------------------- MMAR_1789|M.marinum_M -------------------------- MAV_3773|M.avium_104 -------------------------- Mflv_4183|M.gilvum_PYR-GCK -------------------------- Mvan_2180|M.vanbaalenii_PYR-1 -------------------------- MSMEG_2427|M.smegmatis_MC2_155 -------------------------- TH_1479|M.thermoresistible__bu DRGDAFAAAVRAAIR----------- MAB_3238c|M.abscessus_ATCC_199 -------------------------- MUL_1336|M.ulcerans_Agy99 DGGEFLDNYLRVTRRAKAVVRKVFGS