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M. avium 104 MAV_3773 (glnD)

annotation: PII uridylyl-transferase
coordinates: 3897867 - 3900311
length: 814

TPTGPDPSGHQNACGAVDLAASRRQLLSEGGKLHAAELRHAWLDLHESWLAAKAAQIGIADDSGFALVGI
GGLGRHELLPYSDLDLMLLHDNKSDEVLQRVADALWYPLWDANVRLDHSVRTVSGALGVANGDMIAALGM
LDARHVAGDARLSDELIAGARRQWRSAIRSRMDELVEMTQARWDRCGRIAQRAEPDLKSGRGGLRDVQLL
DALGVAQLIDRHGMARPESPGGSLDDAHLTLLDVRTELHRVSGRGLDQLLAQYGDELSAALHIGDRFDLA
RKLSDASRTIAYHAETGLRTAENALPRRGVSALVRRPKRRPLDEGVVEYAGEIVLARDARPDTDVGLVLR
VAAASASTGLPIGAATLSRLAAAAPEMPEPWPREALDDLLVLLSAGPTTVATIEALDRTGLWGRLLPEWD
AIRDLPPRDVAHKWTVDRHVIETTVNAAPLATRVARPDLLALGALLHDIGKGRGVDHSVLGAGLALEIGP
RLGMAPADVELLAQLVRHHLLLPVAATRSDLNDPKTIERVSKTLGEDPLLLEVLHALTEADSKATGPGVW
SDWKASLIDDLVRRCRMVMAGEPLPKVEPAAPQYLSLAADRGVHVQIKPGGGERLDVVMAAPDQRGLVSK
AAAVLALNSLRIHSASASTHEGFAVVEFVVSPLFGSPPEAGLLRQQFTGALGGDVDVLGTLEKRDSDAVG
AATRRAGEVQVGVPVTRSTAPPRILWVDTAAADQLIVEVRAMDRLGLLALLTRALERAGTDIVWAKVNTF
GSTAADAFCVTAGDAGARDAVEQSLLTVLGGPAVEVLEEPVGD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_3773glnD-100% (814)PII uridylyl-transferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2942cglnD0.075.90% (805) PII uridylyl-transferase
M. gilvum PYR-GCKMflv_4183-0.062.20% (791) PII uridylyl-transferase
M. tuberculosis H37RvRv2918cglnD0.075.90% (805) PII uridylyl-transferase
M. leprae Br4923MLBr_01630glnE8e-0625.31% (320) bifunctional glutamine-synthetase
M. abscessus ATCC 19977MAB_3238c-0.062.88% (792) PII uridylyl-transferase
M. marinum MMMAR_1789glnD0.075.12% (804) uridylyltransferase GlnD
M. smegmatis MC2 155MSMEG_2427glnD0.064.14% (792) PII uridylyl-transferase
M. thermoresistible (build 8)TH_1479glnD0.066.62% (695) PROBABLE
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_2180-0.062.29% (814) PII uridylyl-transferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2942c|M.bovis_AF2122/97           -------MEAE-----------------SPCAASDLAVA---------RR
Rv2918c|M.tuberculosis_H37Rv        -------MEAE-----------------SPCAASDLAVA---------RR
MMAR_1789|M.marinum_M               -------MEPG-----------------SVRAASDLAAA---------RR
MAV_3773|M.avium_104                -------MTPTGP---------DPSGHQNACGAVDLAAS---------RR
Mflv_4183|M.gilvum_PYR-GCK          -------MKDSTSKPAAGASRWERPAAVSSRPATDLVAA---------AE
Mvan_2180|M.vanbaalenii_PYR-1       -------MKEQKSQPAAGAPRWERPAAGSLRPATDLVAA---------AD
MSMEG_2427|M.smegmatis_MC2_155      -------MAEHKTQSAG--ASHKGAPAGSSRPANDLAAA---------VS
MAB_3238c|M.abscessus_ATCC_199      -----------------------------MGAATDLVAA---------RA
TH_1479|M.thermoresistible__bu      -------MTEQTPGPASGSFPAKDPEAVCSKPARDLVAA---------TE
MLBr_01630|M.leprae_Br4923          MCCTTVVVVRKPATERLKRPSVGRLGLFDPHAAENLALLGWYDYDCREHV
                                                                    * :*.             

Mb2942c|M.bovis_AF2122/97           ELLSGNHRELDPVGLRQTWLDLHES----WLIDKADEIGIADASGFAIVG
Rv2918c|M.tuberculosis_H37Rv        ELLSGNHRELDPVGLRQTWLDLHES----WLIDKADEIGIADASGFAIVG
MMAR_1789|M.marinum_M               QLLSDDHRDMDPAELRQAWLDLHES----WLIAKAAQIGIADDSGYAIVG
MAV_3773|M.avium_104                QLLSEGG-KLHAAELRHAWLDLHES----WLAAKAAQIGIADDSGFALVG
Mflv_4183|M.gilvum_PYR-GCK          QLLAGGARPLDSAALRDALLDLHDF----WLTTKATEIGITATSGFAIVA
Mvan_2180|M.vanbaalenii_PYR-1       QLLSG-SRQLDAAALRDALLDLYDF----WLTTKASEIGITATSGFAIVA
MSMEG_2427|M.smegmatis_MC2_155      QLLTGGPRQLDSAALRDALLDLYEF----WLTTKATELGITADSGFAIVA
MAB_3238c|M.abscessus_ATCC_199      QLLGD-SGRLNAAAIREAMTDLNEL----WLTTKAAEVGITDSSGFAIVA
TH_1479|M.thermoresistible__bu      RLLAGGARQLDAASLRYALLDLHEL----WLNTKAAEIGITPVSGFSIVA
MLBr_01630|M.leprae_Br4923          DLLWSLSRAPDADAVLRPMVRLFENPATGWDELNAALLTDRGLRGRLFAV
                                     **       ..  :  .   * :     *   :*  :      *  :. 

Mb2942c|M.bovis_AF2122/97           VGG-----------------LGRRELLP-----YSDLDVLLLHDG-KPAD
Rv2918c|M.tuberculosis_H37Rv        VGG-----------------LGRRELLP-----YSDLDVLLLHDG-KPAD
MMAR_1789|M.marinum_M               VGG-----------------LGRRELLP-----YSDLDLVLVHDG-KPVE
MAV_3773|M.avium_104                IGG-----------------LGRHELLP-----YSDLDLMLLHDN-KSDE
Mflv_4183|M.gilvum_PYR-GCK          TGG-----------------LGRGELLP-----YSDLDLMLLHDN-MPAE
Mvan_2180|M.vanbaalenii_PYR-1       TGG-----------------LGRGELLP-----YSDLDLMLLHDN-MPPE
MSMEG_2427|M.smegmatis_MC2_155      TGG-----------------LGRGEMLP-----YSDLDLMLLHDN-MPVD
MAB_3238c|M.abscessus_ATCC_199      LGG-----------------LGRREMLP-----YSDLDLVLLHDENIAPE
TH_1479|M.thermoresistible__bu      TGG-----------------LGRGELVP-----HSDLDLMLLHDG-MPTE
MLBr_01630|M.leprae_Br4923          LGSSLALGDHLVAHPQSWKLLRGRVSLPSRTQLHQAFDECVSNFGDDPLD
                                     *.                 *     :*     :. :*  : :    . :

Mb2942c|M.bovis_AF2122/97           ILRPVADRLWYPLWDANIRLDHS--VRTVSEALTIANSDLMAALGMLEAR
Rv2918c|M.tuberculosis_H37Rv        ILRPVADRLWYPLWDANIRLDHS--VRTVSEALTIANSDLMAALGMLEAR
MMAR_1789|M.marinum_M               ELGDVADALWYPLWDANIRLDHS--VRTVSDALGVAGADMAAALGMLEAR
MAV_3773|M.avium_104                VLQRVADALWYPLWDANVRLDHS--VRTVSGALGVANGDMIAALGMLDAR
Mflv_4183|M.gilvum_PYR-GCK          IVGEVAELLWYPLWDANIRLDHS--VRTVPEALRVAGEDISAGLAMLEAR
Mvan_2180|M.vanbaalenii_PYR-1       IVSEVAELLWYPLWDANIRLDHS--VRTVPEALRVAGTDISAGLAMLEAR
MSMEG_2427|M.smegmatis_MC2_155      VVTEVAEKLWYPLWDANIRLDHS--VRTVPEALKVAGEDISVGLAMLDVR
MAB_3238c|M.abscessus_ATCC_199      TLSEVADGLWYPLWDANIRLDHS--VRTVADTLHVAGQEMSAALALLDAR
TH_1479|M.thermoresistible__bu      LVGRIAEQLWYPLWDANIRIDHS--VRTVAEALAVADADIAAGLAMLEAR
MLBr_01630|M.leprae_Br4923          APDSVLPRLRTLYCDQLLVLAALDLAATVEDEPVLPFTLVAAQLADIADA
                                        :   *     *  : :     . **     :.   : . *. :   

Mb2942c|M.bovis_AF2122/97           HIAGDQQLSFALIDGVRRQWRNGIRSR----MGELVEMTYARWRRCGRIA
Rv2918c|M.tuberculosis_H37Rv        HIAGDQQLSFALIDGVRRQWRNGIRSR----MGELVEMTYARWRRCGRIA
MMAR_1789|M.marinum_M               HIVGDQQLSASLIDGVRRQWRSGIRSR----MNELVDMTHDRWLRCGRVA
MAV_3773|M.avium_104                HVAGDARLSDELIAGARRQWRSAIRSR----MDELVEMTQARWDRCGRIA
Mflv_4183|M.gilvum_PYR-GCK          HIAGDADLSSLLIGGARRQWRTGIAPR----FEELVEHARARWQRSGEIA
Mvan_2180|M.vanbaalenii_PYR-1       HIAGDGDLSSLLIGGARRQWRTGIASR----FDELVEHTRARWQRSGEIA
MSMEG_2427|M.smegmatis_MC2_155      HIAGDADLSSLLVGGARRQWRIGIASR----FEELVEHAQARWQRSGQIA
MAB_3238c|M.abscessus_ATCC_199      HIAGDAQLSSLMIGGVRQQWRSQIRTR----LDELVEYTQARWRRSGEIA
TH_1479|M.thermoresistible__bu      HIAGDADLSALVIDGARRHWRTTIASR----FDELIDHTRARWERSGQIA
MLBr_01630|M.leprae_Br4923          AMATALRVAEKIVCGDRTPPRLAVIAMGKWGARELNYVSDVDIIFVAEQA
                                     :.    ::  :: * *   *  : .       **   :       .. *

Mb2942c|M.bovis_AF2122/97           QRAEPDLKLGRGGLRDVQLLDALALAQLIDRHG-IGHTDRPAGSLDGAYR
Rv2918c|M.tuberculosis_H37Rv        QRAEPDLKLGRGGLRDVQLLDALALAQLIDRHG-IGHTDLPAGSLDGAYR
MMAR_1789|M.marinum_M               NRAEPDLKSGRGGLRDVQLLDALAIAQLIDRHG-LVTPDMPVGSLDAAYL
MAV_3773|M.avium_104                QRAEPDLKSGRGGLRDVQLLDALGVAQLIDRHG-MARPESPGGSLDDAHL
Mflv_4183|M.gilvum_PYR-GCK          HRAEPDLKCGRGGLRDVQLLNALAIAQLADVYP-SRSLASPTETLGEANL
Mvan_2180|M.vanbaalenii_PYR-1       HRAEPDLKCGRGGLRDVQLLNALAIAQLADVYP-SRSLASPTETLGEAHL
MSMEG_2427|M.smegmatis_MC2_155      HRAEPDLKSGRGGLRDVQLLNALAIAQLADVYP-SRALASPTGTLGGAHL
MAB_3238c|M.abscessus_ATCC_199      HRAEPDLKSGRGGLRDVQLLRALAIAQLTDSGL-AKSFDG-------AHS
TH_1479|M.thermoresistible__bu      HRAEPDLKCGRGGLRDVQLLNALAIAQLADGYP-SSSLASPTGTLGDAHL
MLBr_01630|M.leprae_Br4923          DPLSTRVASEMMRVASEAFFQVDAGLRPEGRNGELVRTVESHIAYYQRWA
                                    .  .. :      : .  :: . .  :  .                    

Mb2942c|M.bovis_AF2122/97           TLLDVRTELHRVSGRGRDHLLAQFADEISAALGFG-DRFDLARTLSSAGR
Rv2918c|M.tuberculosis_H37Rv        TLLDVRTELHRVSGRGRDHLLAQFADEISAALGFG-DRFDLARTLSSAGR
MMAR_1789|M.marinum_M               TLLNVRTELHRVSGRGRDLLLAQHADDISAALHFG-DRFDLARMLSSAGR
MAV_3773|M.avium_104                TLLDVRTELHRVSGRGLDQLLAQYGDELSAALHIG-DRFDLARKLSDASR
Mflv_4183|M.gilvum_PYR-GCK          ALLNVRTELHRVAGRGRELLLAQHADEIGASLRIG-DRFDLARTLSDAAR
Mvan_2180|M.vanbaalenii_PYR-1       SLLNVRTELHRVAGRGRELLLAQHADEIGAALHIG-DRFDLARMLSDAAR
MSMEG_2427|M.smegmatis_MC2_155      ALLNVRTELHRVSGRGRELLLAQHADEIGAALRIG-DRFDLARMLSDAAR
MAB_3238c|M.abscessus_ATCC_199      VILDVRTELHRVAGRERDQLLAQFADEIGAALRIG-DRFDLARMLSDAAR
TH_1479|M.thermoresistible__bu      ALLDVRTELHRIAGRGRDLLQAQYADEIAAALRIG-DRFDLARLLSDAAR
MLBr_01630|M.leprae_Br4923          KTWEFQALLKARSAVGDAELGERYLAALMPMVWAACERADFVAEVQAMRR
                                       :.:: *:  :.     *  :.   : . :  . :* *:.  :.   *

Mb2942c|M.bovis_AF2122/97           TIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARD
Rv2918c|M.tuberculosis_H37Rv        TIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARD
MMAR_1789|M.marinum_M               TIAYHAESGLRTACNALPRRGISALRRRPKRRPLDEGVVECANEIVLARD
MAV_3773|M.avium_104                TIAYHAETGLRTAENALPRRGVSALVRRPKRRPLDEGVVEYAGEIVLARD
Mflv_4183|M.gilvum_PYR-GCK          TVSYYVDAGIRTAANSLPRRGLAAL-RRPVRRPLDEGVIEFAGEVILARD
Mvan_2180|M.vanbaalenii_PYR-1       TVSYYVDAGIRTAANALPRRGLAVL-RRPVRRPLDEGVIEFNGEVILARD
MSMEG_2427|M.smegmatis_MC2_155      TVSYYVDSGIRTAANALPRRGFAAL-RRPVRRPLDEGVIEFAGEVILARD
MAB_3238c|M.abscessus_ATCC_199      TISYSVDVGLRAAANSIPRRGISAL-RRTVRRPIDEGVVEHAGEVVLARD
TH_1479|M.thermoresistible__bu      TVSYYVDSGLRTAANALPRRGFAAL-RRPLRRPLDEGVVEYAGEVILARD
MLBr_01630|M.leprae_Br4923          RVEQLVPADVRGRELKLGSGGLRDVEFAVQLLQLVHGRSDESLHVVSTVD
                                     :   .  .:*     :   *.  :        : .*  :   .:: : *

Mb2942c|M.bovis_AF2122/97           AEPEH-DPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALD
Rv2918c|M.tuberculosis_H37Rv        AEPEH-DPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALD
MMAR_1789|M.marinum_M               AQPEQ-DAGLVLRVAAAAAHAGLPIGAATLRRLADSAAELPTPWPREVLD
MAV_3773|M.avium_104                ARPDT-DVGLVLRVAAASASTGLPIGAATLSRLAAAAPEMPEPWPREALD
Mflv_4183|M.gilvum_PYR-GCK          ARPER-DPGLILRVAAASATTGLPIAGSTLSRLVEAAPELRTPWPRQALK
Mvan_2180|M.vanbaalenii_PYR-1       ARPER-DPGLILRVAAASATTGLPMAASTLSRLVEAAPELRTPWPGQALK
MSMEG_2427|M.smegmatis_MC2_155      ARPER-DPGLVLRVAAASATTGLPIAVSTLSRLAETAPELRTPWPSQALK
MAB_3238c|M.abscessus_ATCC_199      ARPER-DPSLILRVAAASATTGLPIAASTLARLAESAPELRTPWPREALK
TH_1479|M.thermoresistible__bu      ARPAR-DPGLILRVAAASATTGLPIAASTLSRLAATAPELRAPWPRPALN
MLBr_01630|M.leprae_Br4923          ALAALGEGGYIGREDAANLTASYEFLRLLEHRLQLQRLKRTHLLPEDGDE
                                    * .   : . : *  **   :.  :      **     .     *    .

Mb2942c|M.bovis_AF2122/97           DLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVD
Rv2918c|M.tuberculosis_H37Rv        DLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVD
MMAR_1789|M.marinum_M               DLLVVLLAGPTAVVTIEALDRTGLWGRLLPEWGAIRDLPPRDVAHKWTVD
MAV_3773|M.avium_104                DLLVLLSAGPTTVATIEALDRTGLWGRLLPEWDAIRDLPPRDVAHKWTVD
Mflv_4183|M.gilvum_PYR-GCK          DLLVMLAAGPSAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVD
Mvan_2180|M.vanbaalenii_PYR-1       DLLVMLAAGPSAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVD
MSMEG_2427|M.smegmatis_MC2_155      DLLVLLAAGPAAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVD
MAB_3238c|M.abscessus_ATCC_199      DLLVLLESGRPALATIEALDRTGLWGRLFPEWGPVRDLPPRDIVHIWTVD
TH_1479|M.thermoresistible__bu      DLLVLLGAGPAAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDIVHVWTVD
MLBr_01630|M.leprae_Br4923          EAVRWLAR-AAHIRPDGRHDAAGVLREELKNQNLRVSQLHAKLFYQPLLE
                                    : :  *    . : .    * :*:  . : :     .    .: :   ::

Mb2942c|M.bovis_AF2122/97           RHVVETAVHAAPLATRVARPDLLALGALLHDIGK-------GRGTDHSVL
Rv2918c|M.tuberculosis_H37Rv        RHVVETAVHAAPLATRVARPDLLALGALLHDIGK-------GRGTDHSVL
MMAR_1789|M.marinum_M               RHLIETAVQAAPLTTQVARPDLLALGALLHDIGK-------GRGADHSVL
MAV_3773|M.avium_104                RHVIETTVNAAPLATRVARPDLLALGALLHDIGK-------GRGVDHSVL
Mflv_4183|M.gilvum_PYR-GCK          RHLVETVSRASAFTTRVSRPDLLLLGALVHDIGK-------GRGGDHSVI
Mvan_2180|M.vanbaalenii_PYR-1       RHLVETVSRASAFTTRVSRPDLLILGALVHDIGK-------GRGGDHSVI
MSMEG_2427|M.smegmatis_MC2_155      RHLVETVSRASAFTTRVSRPDLLLLGALCHDIGK-------GRGGDHSVI
MAB_3238c|M.abscessus_ATCC_199      RHLVETVVQASAFTTRVSRPDLLVLGALVHDIGK-------GRGGDHSVV
TH_1479|M.thermoresistible__bu      RHLTETVAQASALTTRVSRPDLLLLGALLHDIGK-------GRGGDHSVI
MLBr_01630|M.leprae_Br4923          SIGPASLEIRHGMTSEAAERQLATLGYEGSQTALKHISALVNQSGRRGRV
                                         :      :::..:. :*  **    : .        .:.  :. :

Mb2942c|M.bovis_AF2122/97           GAELVIPVCTRLGLSP-PDVWTLSKLVRHHLLLPITATRRDLNDPKTIEA
Rv2918c|M.tuberculosis_H37Rv        GAELVIPVCTRLGLSP-PDVRTLSKLVRHHLLLPITATRRDLNDPKTIEA
MMAR_1789|M.marinum_M               GAEMVVAIGQRLGISA-PDIDLLSKLVRHHLLLPVVATRSDLNDPSTITR
MAV_3773|M.avium_104                GAGLALEIGPRLGMAP-ADVELLAQLVRHHLLLPVAATRSDLNDPKTIER
Mflv_4183|M.gilvum_PYR-GCK          GAELAHQIGSRLGLWP-SDIKILAQVVRYHLLLPHTATRRDLQDAATISA
Mvan_2180|M.vanbaalenii_PYR-1       GAELADQIGSRLGLWP-SDIRVLSTLVRHHLLLPHTATRRDLQDPATIAA
MSMEG_2427|M.smegmatis_MC2_155      GAELATQIGTRLGLWP-SDIDVLSKLVRYHLLLPETATRRDLQDPKTIAA
MAB_3238c|M.abscessus_ATCC_199      GADLAVQIGTRLGLWP-SDVELLSKIVRYHLLLPNTATRRDLADPETIDG
TH_1479|M.thermoresistible__bu      GAELAAQIGARLGLWP-SDIDILVKLVRHHLLLVRTATRRDLDDPRTIES
MLBr_01630|M.leprae_Br4923          QSVLLPRLLNWMSYAPDPDGGLLAYRRLSEALSAETWYLSTLRDKPAVAR
                                     : :   :   :.  . .*   *      . *   .     * *  ::  

Mb2942c|M.bovis_AF2122/97           VSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVM
Rv2918c|M.tuberculosis_H37Rv        VSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVM
MMAR_1789|M.marinum_M               VSEALGGDPQLLEVLRALTEADSKATGPGVWSDWKASLVDDLVSRCRLAM
MAV_3773|M.avium_104                VSKTLGEDPLLLEVLHALTEADSKATGPGVWSDWKASLIDDLVRRCRMVM
Mflv_4183|M.gilvum_PYR-GCK          VVDALDGDPAVLELLHVLAEADSLATGPGVWGDWKASLLGELVRRCRMVM
Mvan_2180|M.vanbaalenii_PYR-1       VVDALDGDLVVLELLHVLAEADSLATGPGVWGDWKASLIGELVRRCRLVM
MSMEG_2427|M.smegmatis_MC2_155      VVDALGGDMVVLELLDVLAEADSLATGPGVWGDWKASLIGDLVRRCRLVM
MAB_3238c|M.abscessus_ATCC_199      VVNTLGGDLLLLELLQQLAEADSLATGPGVWGDWKASLIGELVRKCRLVM
TH_1479|M.thermoresistible__bu      VVDALGPDPVLLDLLHALVEADSLATGPGVWGEWKAALIGDLVRRCRLVM
MLBr_01630|M.leprae_Br4923          RLMHVLGTSVYVPDLLMRAPEVIQSYGDGLAGPKLLEAEPAMVARALITS
                                        :      :  *         : * *: .         :* :. :. 

Mb2942c|M.bovis_AF2122/97           AG------ESLPQAEPTAPHYLSLAADHGVHVEISPRDGERI-DAVIVAP
Rv2918c|M.tuberculosis_H37Rv        AG------ESLPQAEPTAPHYLSLAADHGVHVEISPRDGERI-DAVIVAP
MMAR_1789|M.marinum_M               AG------EPLPRADPEAPHYVSLSADHGVHVEIAPGESARMYQVVMAAP
MAV_3773|M.avium_104                AG------EPLPKVEPAAPQYLSLAADRGVHVQIKPGGGERL-DVVMAAP
Mflv_4183|M.gilvum_PYR-GCK          AG------EPLPHPDPVDPRFISLAGQVGVHVELTPTDTPHIYQVTMIAP
Mvan_2180|M.vanbaalenii_PYR-1       AG------EPLPHPDPVDPRFVALAGDGGVHVELTPAEHSHIYNVTMIAP
MSMEG_2427|M.smegmatis_MC2_155      AG------EPLPHPDPIDPRFLEIAADVGVHVELTPGDGQHIFNVTMIAP
MAB_3238c|M.abscessus_ATCC_199      RG------EQLPEPDPIDPELLSLAADGGVQVRLVPAGSPHMYIVSLIAP
TH_1479|M.thermoresistible__bu      AG------EPLPHPDPIDPQHLSLAARGGVHVDLVPGDGPHIYQVTLVAP
MLBr_01630|M.leprae_Br4923          AGRHTDPIRAIDAARSLRRRELARVGSADLLGLLEVTEVCKALTSVWVAV
                                     *      . :    .   . :   .  .:   :      :       * 

Mb2942c|M.bovis_AF2122/97           DERGLVS----------KAAAVLALNSLRVHSASVNVHQGVAITEFVVSP
Rv2918c|M.tuberculosis_H37Rv        DERGLVS----------KAAAVLALNSLRVHSASVNVHQGVAITEFVVSP
MMAR_1789|M.marinum_M               NKPGLVS----------KAAAVLALNSLGVHSAWVNSHEGVAITQFVVSP
MAV_3773|M.avium_104                DQRGLVS----------KAAAVLALNSLRIHSASASTHEGFAVVEFVVSP
Mflv_4183|M.gilvum_PYR-GCK          DSRGVLS----------KAAGVMALNSLRVHSASVNGHEGSAINSFVVSP
Mvan_2180|M.vanbaalenii_PYR-1       DSRGLLS----------KTAGVLALNSLRVHSASVNGHEGAAINTFVVSP
MSMEG_2427|M.smegmatis_MC2_155      DRRGLLS----------KAAGVLALNSLRVHSASVNSHEGSAINTFVVSP
MAB_3238c|M.abscessus_ATCC_199      DQRGLLS----------KAAGVLSLNSLRVFSASVASHAGSAINTFEVSP
TH_1479|M.thermoresistible__bu      DRRGLLS----------KAAGVLALNSLRVHSASVNSHHGSAINTFVVSP
MLBr_01630|M.leprae_Br4923          LQAALDAVIRAYLPDGDKAPAAIAVIGMGRLGGAELGYGSDADVMFVCEP
                                       .: :          *:...::: .:   ..    : . *   *  .*

Mb2942c|M.bovis_AF2122/97           LFGSPPAAELVRQQFVGA----------LNGDVDVLGMLQKRDSD-----
Rv2918c|M.tuberculosis_H37Rv        LFGSPPAAELVRQQFVGA----------LNGDVDVLGMLQKRDSD-----
MMAR_1789|M.marinum_M               LFGTPAAADLLRQQFVGA----------LSGDIDALAMVEKRDSE-----
MAV_3773|M.avium_104                LFGSPPEAGLLRQQFTGA----------LGGDVDVLGTLEKRDSD-----
Mflv_4183|M.gilvum_PYR-GCK          RFGTPPAAELLRQQLILA----------IDGELDVMGALEKKE-------
Mvan_2180|M.vanbaalenii_PYR-1       RFGSPPAAELLRQQLILA----------IDGELDVMGALEKKE-------
MSMEG_2427|M.smegmatis_MC2_155      HFGSPPAADLLRQQFVLA----------LDGDLDVIGSLERRERE-----
MAB_3238c|M.abscessus_ATCC_199      RFGSPPAAGLLRQQLISA----------IDGDTDIIAALDERERE-----
TH_1479|M.thermoresistible__bu      HFGAPPAANLLRQQLILA----------LDGDLDVLAALERRDHDGAPGS
MLBr_01630|M.leprae_Br4923          AIGVEDAQALRWSGMIAERVCRLLRTPSVDPPLDVDANLRPEGRNGPLVR
                                     :*      *  . :             :.   *  . :  .        

Mb2942c|M.bovis_AF2122/97           -------------------AASLVSARAGDVQAG----------------
Rv2918c|M.tuberculosis_H37Rv        -------------------AASLVSARAGDVQAG----------------
MMAR_1789|M.marinum_M               -------------------ATSNASQRAGEVVAG----------------
MAV_3773|M.avium_104                -------------------AVGAATRRAGEVQVG----------------
Mflv_4183|M.gilvum_PYR-GCK          -------------------AESVATGRAGEVRAA----------------
Mvan_2180|M.vanbaalenii_PYR-1       -------------------AESTATGRAGEIRAA----------------
MSMEG_2427|M.smegmatis_MC2_155      -------------------AAQYPTTRAGEILAA----------------
MAB_3238c|M.abscessus_ATCC_199      -------------------SAQFATGVVGDAAPA----------------
TH_1479|M.thermoresistible__bu      HR--------------PGEPAXXXVGVAAESIAAGLTAFEVGRHRAELIA
MLBr_01630|M.leprae_Br4923          TLGAYAAYYAQWAQPWEIQALLRAHAVAGDADLG----------------
                                                       .       ..:   .                

Mb2942c|M.bovis_AF2122/97           -----------------VPVTRTAAPPRILWLDTAA-PAKLILEVRAMDR
Rv2918c|M.tuberculosis_H37Rv        -----------------VPVTRTAAPPRILWLDTAA-PAKLILEVRAMDR
MMAR_1789|M.marinum_M               -----------------VPVTRSTAPPRILWLDSAA-PDQLVLEVRSMDR
MAV_3773|M.avium_104                -----------------VPVTRSTAPPRILWVDTAA-ADQLIVEVRAMDR
Mflv_4183|M.gilvum_PYR-GCK          -----------------VPINAPTAPPKVLWHEPSG-SGHVVAEIRATDR
Mvan_2180|M.vanbaalenii_PYR-1       -----------------VPINPPTAPPRVLWHEGAG-AGQVVAEIRATDR
MSMEG_2427|M.smegmatis_MC2_155      -----------------VPANHVPAPPRLLWADGSN-PGELIVQIRTIDR
MAB_3238c|M.abscessus_ATCC_199      -----------------VPTNYAPAPPRIRWFEPAGNADQQIVEIRTSDA
TH_1479|M.thermoresistible__bu      TAGGISYVDDSKATNPHAAAASIAAHPRVVWIAGGLLKGAAVDELVAEVA
MLBr_01630|M.leprae_Br4923          -------------QRFLLMADKMRYPPDGVSAEAVREIRRMKARVEAERL
                                                              *                .: :   

Mb2942c|M.bovis_AF2122/97           AG--------LLAL---------LAGALEGAGAGIVWAKVNT--------
Rv2918c|M.tuberculosis_H37Rv        AG--------LLAL---------LAGALEGAGAGIVWAKVNT--------
MMAR_1789|M.marinum_M               PG--------LLAL---------LTRALERAGADIVWAKVNT--------
MAV_3773|M.avium_104                LG--------LLAL---------LTRALERAGTDIVWAKVNT--------
Mflv_4183|M.gilvum_PYR-GCK          TG--------LLAV---------LTRVFERAGVDIAWAKVTT--------
Mvan_2180|M.vanbaalenii_PYR-1       AG--------LLAV---------LTRVLERAGVDIAWAKVTT--------
MSMEG_2427|M.smegmatis_MC2_155      AG--------LLAR---------LTAVFERDGVDIAWAKVTT--------
MAB_3238c|M.abscessus_ATCC_199      PG--------LLAR---------ITATLERHGVDIAWAKVNT--------
TH_1479|M.thermoresistible__bu      DR--------LAGXXLIGRDREIIAQALSRHAPEVPVVSVVTGDD----S
MLBr_01630|M.leprae_Br4923          PRGADPHTHTKLGRGGLADIEWTVQLMQLRHAHELPALHKTSTLESLDAI
                                                .          :       .  :      :        

Mb2942c|M.bovis_AF2122/97           -----FGSTAADVFCVTVPAELD---ARAAVEQHLLEVLGASVDVVVDEP
Rv2918c|M.tuberculosis_H37Rv        -----FGSTAADVFCVTVPAELD---ARAAVEQHLLEVLGASVDVVVDEP
MMAR_1789|M.marinum_M               -----FGSTAADVFCVTVSAGLEEPQARAAMEQQLSAVLGGSADVLLDEP
MAV_3773|M.avium_104                -----FGSTAADAFCVTA-GDAG---ARDAVEQSLLTVLGGPAVEVLEEP
Mflv_4183|M.gilvum_PYR-GCK          -----MGSSVIDVFGIVLPAG-EDA-VRESLEKQLLAVLPAPPQPKPVRE
Mvan_2180|M.vanbaalenii_PYR-1       -----LGSSVVDAFGIVLPAD-GAA-ARQNLERELFAVLPAPP-AKPAEV
MSMEG_2427|M.smegmatis_MC2_155      -----LGSSVVDAFGITTADGRTEQ-VRQELERDLYAVLPTPPPAKPAEQ
MAB_3238c|M.abscessus_ATCC_199      -----LGSSVVDTFCLSTGPE------QAVLEAAIASVLPAVA-PQPKKA
TH_1479|M.thermoresistible__bu      GMQATAGAPVNAVTRVVEATEPIGP-AVMTAAVAAARALASPGDTVLLAP
MLBr_01630|M.leprae_Br4923          AAANLIPEADVDLLRQAWLTATRARNALVLVRGKTTDQLPGPGRQLNAVA
                                            .                             *           

Mb2942c|M.bovis_AF2122/97           VGD-------------------------------
Rv2918c|M.tuberculosis_H37Rv        VGD-------------------------------
MMAR_1789|M.marinum_M               VGD-------------------------------
MAV_3773|M.avium_104                VGD-------------------------------
Mflv_4183|M.gilvum_PYR-GCK          EAS-------------------------------
Mvan_2180|M.vanbaalenii_PYR-1       EAS-------------------------------
MSMEG_2427|M.smegmatis_MC2_155      AS--------------------------------
MAB_3238c|M.abscessus_ATCC_199      AAS-------------------------------
TH_1479|M.thermoresistible__bu      AGASFDQFSGYADRGDAFAAAVRAAIR-------
MLBr_01630|M.leprae_Br4923          VAAGWPSDDGSEFLDNYLRVTRRAKTFVRKVFGS
                                     .