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TPTGPDPSGHQNACGAVDLAASRRQLLSEGGKLHAAELRHAWLDLHESWLAAKAAQIGIADDSGFALVGI GGLGRHELLPYSDLDLMLLHDNKSDEVLQRVADALWYPLWDANVRLDHSVRTVSGALGVANGDMIAALGM LDARHVAGDARLSDELIAGARRQWRSAIRSRMDELVEMTQARWDRCGRIAQRAEPDLKSGRGGLRDVQLL DALGVAQLIDRHGMARPESPGGSLDDAHLTLLDVRTELHRVSGRGLDQLLAQYGDELSAALHIGDRFDLA RKLSDASRTIAYHAETGLRTAENALPRRGVSALVRRPKRRPLDEGVVEYAGEIVLARDARPDTDVGLVLR VAAASASTGLPIGAATLSRLAAAAPEMPEPWPREALDDLLVLLSAGPTTVATIEALDRTGLWGRLLPEWD AIRDLPPRDVAHKWTVDRHVIETTVNAAPLATRVARPDLLALGALLHDIGKGRGVDHSVLGAGLALEIGP RLGMAPADVELLAQLVRHHLLLPVAATRSDLNDPKTIERVSKTLGEDPLLLEVLHALTEADSKATGPGVW SDWKASLIDDLVRRCRMVMAGEPLPKVEPAAPQYLSLAADRGVHVQIKPGGGERLDVVMAAPDQRGLVSK AAAVLALNSLRIHSASASTHEGFAVVEFVVSPLFGSPPEAGLLRQQFTGALGGDVDVLGTLEKRDSDAVG AATRRAGEVQVGVPVTRSTAPPRILWVDTAAADQLIVEVRAMDRLGLLALLTRALERAGTDIVWAKVNTF GSTAADAFCVTAGDAGARDAVEQSLLTVLGGPAVEVLEEPVGD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_3773 | glnD | - | 100% (814) | PII uridylyl-transferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2942c | glnD | 0.0 | 75.90% (805) | PII uridylyl-transferase |
M. gilvum PYR-GCK | Mflv_4183 | - | 0.0 | 62.20% (791) | PII uridylyl-transferase |
M. tuberculosis H37Rv | Rv2918c | glnD | 0.0 | 75.90% (805) | PII uridylyl-transferase |
M. leprae Br4923 | MLBr_01630 | glnE | 8e-06 | 25.31% (320) | bifunctional glutamine-synthetase |
M. abscessus ATCC 19977 | MAB_3238c | - | 0.0 | 62.88% (792) | PII uridylyl-transferase |
M. marinum M | MMAR_1789 | glnD | 0.0 | 75.12% (804) | uridylyltransferase GlnD |
M. smegmatis MC2 155 | MSMEG_2427 | glnD | 0.0 | 64.14% (792) | PII uridylyl-transferase |
M. thermoresistible (build 8) | TH_1479 | glnD | 0.0 | 66.62% (695) | PROBABLE |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_2180 | - | 0.0 | 62.29% (814) | PII uridylyl-transferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2942c|M.bovis_AF2122/97 -------MEAE-----------------SPCAASDLAVA---------RR Rv2918c|M.tuberculosis_H37Rv -------MEAE-----------------SPCAASDLAVA---------RR MMAR_1789|M.marinum_M -------MEPG-----------------SVRAASDLAAA---------RR MAV_3773|M.avium_104 -------MTPTGP---------DPSGHQNACGAVDLAAS---------RR Mflv_4183|M.gilvum_PYR-GCK -------MKDSTSKPAAGASRWERPAAVSSRPATDLVAA---------AE Mvan_2180|M.vanbaalenii_PYR-1 -------MKEQKSQPAAGAPRWERPAAGSLRPATDLVAA---------AD MSMEG_2427|M.smegmatis_MC2_155 -------MAEHKTQSAG--ASHKGAPAGSSRPANDLAAA---------VS MAB_3238c|M.abscessus_ATCC_199 -----------------------------MGAATDLVAA---------RA TH_1479|M.thermoresistible__bu -------MTEQTPGPASGSFPAKDPEAVCSKPARDLVAA---------TE MLBr_01630|M.leprae_Br4923 MCCTTVVVVRKPATERLKRPSVGRLGLFDPHAAENLALLGWYDYDCREHV * :*. Mb2942c|M.bovis_AF2122/97 ELLSGNHRELDPVGLRQTWLDLHES----WLIDKADEIGIADASGFAIVG Rv2918c|M.tuberculosis_H37Rv ELLSGNHRELDPVGLRQTWLDLHES----WLIDKADEIGIADASGFAIVG MMAR_1789|M.marinum_M QLLSDDHRDMDPAELRQAWLDLHES----WLIAKAAQIGIADDSGYAIVG MAV_3773|M.avium_104 QLLSEGG-KLHAAELRHAWLDLHES----WLAAKAAQIGIADDSGFALVG Mflv_4183|M.gilvum_PYR-GCK QLLAGGARPLDSAALRDALLDLHDF----WLTTKATEIGITATSGFAIVA Mvan_2180|M.vanbaalenii_PYR-1 QLLSG-SRQLDAAALRDALLDLYDF----WLTTKASEIGITATSGFAIVA MSMEG_2427|M.smegmatis_MC2_155 QLLTGGPRQLDSAALRDALLDLYEF----WLTTKATELGITADSGFAIVA MAB_3238c|M.abscessus_ATCC_199 QLLGD-SGRLNAAAIREAMTDLNEL----WLTTKAAEVGITDSSGFAIVA TH_1479|M.thermoresistible__bu RLLAGGARQLDAASLRYALLDLHEL----WLNTKAAEIGITPVSGFSIVA MLBr_01630|M.leprae_Br4923 DLLWSLSRAPDADAVLRPMVRLFENPATGWDELNAALLTDRGLRGRLFAV ** .. : . * : * :* : * :. Mb2942c|M.bovis_AF2122/97 VGG-----------------LGRRELLP-----YSDLDVLLLHDG-KPAD Rv2918c|M.tuberculosis_H37Rv VGG-----------------LGRRELLP-----YSDLDVLLLHDG-KPAD MMAR_1789|M.marinum_M VGG-----------------LGRRELLP-----YSDLDLVLVHDG-KPVE MAV_3773|M.avium_104 IGG-----------------LGRHELLP-----YSDLDLMLLHDN-KSDE Mflv_4183|M.gilvum_PYR-GCK TGG-----------------LGRGELLP-----YSDLDLMLLHDN-MPAE Mvan_2180|M.vanbaalenii_PYR-1 TGG-----------------LGRGELLP-----YSDLDLMLLHDN-MPPE MSMEG_2427|M.smegmatis_MC2_155 TGG-----------------LGRGEMLP-----YSDLDLMLLHDN-MPVD MAB_3238c|M.abscessus_ATCC_199 LGG-----------------LGRREMLP-----YSDLDLVLLHDENIAPE TH_1479|M.thermoresistible__bu TGG-----------------LGRGELVP-----HSDLDLMLLHDG-MPTE MLBr_01630|M.leprae_Br4923 LGSSLALGDHLVAHPQSWKLLRGRVSLPSRTQLHQAFDECVSNFGDDPLD *. * :* :. :* : : . : Mb2942c|M.bovis_AF2122/97 ILRPVADRLWYPLWDANIRLDHS--VRTVSEALTIANSDLMAALGMLEAR Rv2918c|M.tuberculosis_H37Rv ILRPVADRLWYPLWDANIRLDHS--VRTVSEALTIANSDLMAALGMLEAR MMAR_1789|M.marinum_M ELGDVADALWYPLWDANIRLDHS--VRTVSDALGVAGADMAAALGMLEAR MAV_3773|M.avium_104 VLQRVADALWYPLWDANVRLDHS--VRTVSGALGVANGDMIAALGMLDAR Mflv_4183|M.gilvum_PYR-GCK IVGEVAELLWYPLWDANIRLDHS--VRTVPEALRVAGEDISAGLAMLEAR Mvan_2180|M.vanbaalenii_PYR-1 IVSEVAELLWYPLWDANIRLDHS--VRTVPEALRVAGTDISAGLAMLEAR MSMEG_2427|M.smegmatis_MC2_155 VVTEVAEKLWYPLWDANIRLDHS--VRTVPEALKVAGEDISVGLAMLDVR MAB_3238c|M.abscessus_ATCC_199 TLSEVADGLWYPLWDANIRLDHS--VRTVADTLHVAGQEMSAALALLDAR TH_1479|M.thermoresistible__bu LVGRIAEQLWYPLWDANIRIDHS--VRTVAEALAVADADIAAGLAMLEAR MLBr_01630|M.leprae_Br4923 APDSVLPRLRTLYCDQLLVLAALDLAATVEDEPVLPFTLVAAQLADIADA : * * : : . ** :. : . *. : Mb2942c|M.bovis_AF2122/97 HIAGDQQLSFALIDGVRRQWRNGIRSR----MGELVEMTYARWRRCGRIA Rv2918c|M.tuberculosis_H37Rv HIAGDQQLSFALIDGVRRQWRNGIRSR----MGELVEMTYARWRRCGRIA MMAR_1789|M.marinum_M HIVGDQQLSASLIDGVRRQWRSGIRSR----MNELVDMTHDRWLRCGRVA MAV_3773|M.avium_104 HVAGDARLSDELIAGARRQWRSAIRSR----MDELVEMTQARWDRCGRIA Mflv_4183|M.gilvum_PYR-GCK HIAGDADLSSLLIGGARRQWRTGIAPR----FEELVEHARARWQRSGEIA Mvan_2180|M.vanbaalenii_PYR-1 HIAGDGDLSSLLIGGARRQWRTGIASR----FDELVEHTRARWQRSGEIA MSMEG_2427|M.smegmatis_MC2_155 HIAGDADLSSLLVGGARRQWRIGIASR----FEELVEHAQARWQRSGQIA MAB_3238c|M.abscessus_ATCC_199 HIAGDAQLSSLMIGGVRQQWRSQIRTR----LDELVEYTQARWRRSGEIA TH_1479|M.thermoresistible__bu HIAGDADLSALVIDGARRHWRTTIASR----FDELIDHTRARWERSGQIA MLBr_01630|M.leprae_Br4923 AMATALRVAEKIVCGDRTPPRLAVIAMGKWGARELNYVSDVDIIFVAEQA :. :: :: * * * : . ** : .. * Mb2942c|M.bovis_AF2122/97 QRAEPDLKLGRGGLRDVQLLDALALAQLIDRHG-IGHTDRPAGSLDGAYR Rv2918c|M.tuberculosis_H37Rv QRAEPDLKLGRGGLRDVQLLDALALAQLIDRHG-IGHTDLPAGSLDGAYR MMAR_1789|M.marinum_M NRAEPDLKSGRGGLRDVQLLDALAIAQLIDRHG-LVTPDMPVGSLDAAYL MAV_3773|M.avium_104 QRAEPDLKSGRGGLRDVQLLDALGVAQLIDRHG-MARPESPGGSLDDAHL Mflv_4183|M.gilvum_PYR-GCK HRAEPDLKCGRGGLRDVQLLNALAIAQLADVYP-SRSLASPTETLGEANL Mvan_2180|M.vanbaalenii_PYR-1 HRAEPDLKCGRGGLRDVQLLNALAIAQLADVYP-SRSLASPTETLGEAHL MSMEG_2427|M.smegmatis_MC2_155 HRAEPDLKSGRGGLRDVQLLNALAIAQLADVYP-SRALASPTGTLGGAHL MAB_3238c|M.abscessus_ATCC_199 HRAEPDLKSGRGGLRDVQLLRALAIAQLTDSGL-AKSFDG-------AHS TH_1479|M.thermoresistible__bu HRAEPDLKCGRGGLRDVQLLNALAIAQLADGYP-SSSLASPTGTLGDAHL MLBr_01630|M.leprae_Br4923 DPLSTRVASEMMRVASEAFFQVDAGLRPEGRNGELVRTVESHIAYYQRWA . .. : : . :: . . : . Mb2942c|M.bovis_AF2122/97 TLLDVRTELHRVSGRGRDHLLAQFADEISAALGFG-DRFDLARTLSSAGR Rv2918c|M.tuberculosis_H37Rv TLLDVRTELHRVSGRGRDHLLAQFADEISAALGFG-DRFDLARTLSSAGR MMAR_1789|M.marinum_M TLLNVRTELHRVSGRGRDLLLAQHADDISAALHFG-DRFDLARMLSSAGR MAV_3773|M.avium_104 TLLDVRTELHRVSGRGLDQLLAQYGDELSAALHIG-DRFDLARKLSDASR Mflv_4183|M.gilvum_PYR-GCK ALLNVRTELHRVAGRGRELLLAQHADEIGASLRIG-DRFDLARTLSDAAR Mvan_2180|M.vanbaalenii_PYR-1 SLLNVRTELHRVAGRGRELLLAQHADEIGAALHIG-DRFDLARMLSDAAR MSMEG_2427|M.smegmatis_MC2_155 ALLNVRTELHRVSGRGRELLLAQHADEIGAALRIG-DRFDLARMLSDAAR MAB_3238c|M.abscessus_ATCC_199 VILDVRTELHRVAGRERDQLLAQFADEIGAALRIG-DRFDLARMLSDAAR TH_1479|M.thermoresistible__bu ALLDVRTELHRIAGRGRDLLQAQYADEIAAALRIG-DRFDLARLLSDAAR MLBr_01630|M.leprae_Br4923 KTWEFQALLKARSAVGDAELGERYLAALMPMVWAACERADFVAEVQAMRR :.:: *: :. * :. : . : . :* *:. :. * Mb2942c|M.bovis_AF2122/97 TIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARD Rv2918c|M.tuberculosis_H37Rv TIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARD MMAR_1789|M.marinum_M TIAYHAESGLRTACNALPRRGISALRRRPKRRPLDEGVVECANEIVLARD MAV_3773|M.avium_104 TIAYHAETGLRTAENALPRRGVSALVRRPKRRPLDEGVVEYAGEIVLARD Mflv_4183|M.gilvum_PYR-GCK TVSYYVDAGIRTAANSLPRRGLAAL-RRPVRRPLDEGVIEFAGEVILARD Mvan_2180|M.vanbaalenii_PYR-1 TVSYYVDAGIRTAANALPRRGLAVL-RRPVRRPLDEGVIEFNGEVILARD MSMEG_2427|M.smegmatis_MC2_155 TVSYYVDSGIRTAANALPRRGFAAL-RRPVRRPLDEGVIEFAGEVILARD MAB_3238c|M.abscessus_ATCC_199 TISYSVDVGLRAAANSIPRRGISAL-RRTVRRPIDEGVVEHAGEVVLARD TH_1479|M.thermoresistible__bu TVSYYVDSGLRTAANALPRRGFAAL-RRPLRRPLDEGVVEYAGEVILARD MLBr_01630|M.leprae_Br4923 RVEQLVPADVRGRELKLGSGGLRDVEFAVQLLQLVHGRSDESLHVVSTVD : . .:* : *. : : .* : .:: : * Mb2942c|M.bovis_AF2122/97 AEPEH-DPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALD Rv2918c|M.tuberculosis_H37Rv AEPEH-DPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALD MMAR_1789|M.marinum_M AQPEQ-DAGLVLRVAAAAAHAGLPIGAATLRRLADSAAELPTPWPREVLD MAV_3773|M.avium_104 ARPDT-DVGLVLRVAAASASTGLPIGAATLSRLAAAAPEMPEPWPREALD Mflv_4183|M.gilvum_PYR-GCK ARPER-DPGLILRVAAASATTGLPIAGSTLSRLVEAAPELRTPWPRQALK Mvan_2180|M.vanbaalenii_PYR-1 ARPER-DPGLILRVAAASATTGLPMAASTLSRLVEAAPELRTPWPGQALK MSMEG_2427|M.smegmatis_MC2_155 ARPER-DPGLVLRVAAASATTGLPIAVSTLSRLAETAPELRTPWPSQALK MAB_3238c|M.abscessus_ATCC_199 ARPER-DPSLILRVAAASATTGLPIAASTLARLAESAPELRTPWPREALK TH_1479|M.thermoresistible__bu ARPAR-DPGLILRVAAASATTGLPIAASTLSRLAATAPELRAPWPRPALN MLBr_01630|M.leprae_Br4923 ALAALGEGGYIGREDAANLTASYEFLRLLEHRLQLQRLKRTHLLPEDGDE * . : . : * ** :. : ** . * . Mb2942c|M.bovis_AF2122/97 DLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVD Rv2918c|M.tuberculosis_H37Rv DLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVD MMAR_1789|M.marinum_M DLLVVLLAGPTAVVTIEALDRTGLWGRLLPEWGAIRDLPPRDVAHKWTVD MAV_3773|M.avium_104 DLLVLLSAGPTTVATIEALDRTGLWGRLLPEWDAIRDLPPRDVAHKWTVD Mflv_4183|M.gilvum_PYR-GCK DLLVMLAAGPSAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVD Mvan_2180|M.vanbaalenii_PYR-1 DLLVMLAAGPSAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVD MSMEG_2427|M.smegmatis_MC2_155 DLLVLLAAGPAAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVD MAB_3238c|M.abscessus_ATCC_199 DLLVLLESGRPALATIEALDRTGLWGRLFPEWGPVRDLPPRDIVHIWTVD TH_1479|M.thermoresistible__bu DLLVLLGAGPAAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDIVHVWTVD MLBr_01630|M.leprae_Br4923 EAVRWLAR-AAHIRPDGRHDAAGVLREELKNQNLRVSQLHAKLFYQPLLE : : * . : . * :*: . : : . .: : :: Mb2942c|M.bovis_AF2122/97 RHVVETAVHAAPLATRVARPDLLALGALLHDIGK-------GRGTDHSVL Rv2918c|M.tuberculosis_H37Rv RHVVETAVHAAPLATRVARPDLLALGALLHDIGK-------GRGTDHSVL MMAR_1789|M.marinum_M RHLIETAVQAAPLTTQVARPDLLALGALLHDIGK-------GRGADHSVL MAV_3773|M.avium_104 RHVIETTVNAAPLATRVARPDLLALGALLHDIGK-------GRGVDHSVL Mflv_4183|M.gilvum_PYR-GCK RHLVETVSRASAFTTRVSRPDLLLLGALVHDIGK-------GRGGDHSVI Mvan_2180|M.vanbaalenii_PYR-1 RHLVETVSRASAFTTRVSRPDLLILGALVHDIGK-------GRGGDHSVI MSMEG_2427|M.smegmatis_MC2_155 RHLVETVSRASAFTTRVSRPDLLLLGALCHDIGK-------GRGGDHSVI MAB_3238c|M.abscessus_ATCC_199 RHLVETVVQASAFTTRVSRPDLLVLGALVHDIGK-------GRGGDHSVV TH_1479|M.thermoresistible__bu RHLTETVAQASALTTRVSRPDLLLLGALLHDIGK-------GRGGDHSVI MLBr_01630|M.leprae_Br4923 SIGPASLEIRHGMTSEAAERQLATLGYEGSQTALKHISALVNQSGRRGRV : :::..:. :* ** : . .:. :. : Mb2942c|M.bovis_AF2122/97 GAELVIPVCTRLGLSP-PDVWTLSKLVRHHLLLPITATRRDLNDPKTIEA Rv2918c|M.tuberculosis_H37Rv GAELVIPVCTRLGLSP-PDVRTLSKLVRHHLLLPITATRRDLNDPKTIEA MMAR_1789|M.marinum_M GAEMVVAIGQRLGISA-PDIDLLSKLVRHHLLLPVVATRSDLNDPSTITR MAV_3773|M.avium_104 GAGLALEIGPRLGMAP-ADVELLAQLVRHHLLLPVAATRSDLNDPKTIER Mflv_4183|M.gilvum_PYR-GCK GAELAHQIGSRLGLWP-SDIKILAQVVRYHLLLPHTATRRDLQDAATISA Mvan_2180|M.vanbaalenii_PYR-1 GAELADQIGSRLGLWP-SDIRVLSTLVRHHLLLPHTATRRDLQDPATIAA MSMEG_2427|M.smegmatis_MC2_155 GAELATQIGTRLGLWP-SDIDVLSKLVRYHLLLPETATRRDLQDPKTIAA MAB_3238c|M.abscessus_ATCC_199 GADLAVQIGTRLGLWP-SDVELLSKIVRYHLLLPNTATRRDLADPETIDG TH_1479|M.thermoresistible__bu GAELAAQIGARLGLWP-SDIDILVKLVRHHLLLVRTATRRDLDDPRTIES MLBr_01630|M.leprae_Br4923 QSVLLPRLLNWMSYAPDPDGGLLAYRRLSEALSAETWYLSTLRDKPAVAR : : : :. . .* * . * . * * :: Mb2942c|M.bovis_AF2122/97 VSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVM Rv2918c|M.tuberculosis_H37Rv VSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVM MMAR_1789|M.marinum_M VSEALGGDPQLLEVLRALTEADSKATGPGVWSDWKASLVDDLVSRCRLAM MAV_3773|M.avium_104 VSKTLGEDPLLLEVLHALTEADSKATGPGVWSDWKASLIDDLVRRCRMVM Mflv_4183|M.gilvum_PYR-GCK VVDALDGDPAVLELLHVLAEADSLATGPGVWGDWKASLLGELVRRCRMVM Mvan_2180|M.vanbaalenii_PYR-1 VVDALDGDLVVLELLHVLAEADSLATGPGVWGDWKASLIGELVRRCRLVM MSMEG_2427|M.smegmatis_MC2_155 VVDALGGDMVVLELLDVLAEADSLATGPGVWGDWKASLIGDLVRRCRLVM MAB_3238c|M.abscessus_ATCC_199 VVNTLGGDLLLLELLQQLAEADSLATGPGVWGDWKASLIGELVRKCRLVM TH_1479|M.thermoresistible__bu VVDALGPDPVLLDLLHALVEADSLATGPGVWGEWKAALIGDLVRRCRLVM MLBr_01630|M.leprae_Br4923 RLMHVLGTSVYVPDLLMRAPEVIQSYGDGLAGPKLLEAEPAMVARALITS : : * : * *: . :* :. :. Mb2942c|M.bovis_AF2122/97 AG------ESLPQAEPTAPHYLSLAADHGVHVEISPRDGERI-DAVIVAP Rv2918c|M.tuberculosis_H37Rv AG------ESLPQAEPTAPHYLSLAADHGVHVEISPRDGERI-DAVIVAP MMAR_1789|M.marinum_M AG------EPLPRADPEAPHYVSLSADHGVHVEIAPGESARMYQVVMAAP MAV_3773|M.avium_104 AG------EPLPKVEPAAPQYLSLAADRGVHVQIKPGGGERL-DVVMAAP Mflv_4183|M.gilvum_PYR-GCK AG------EPLPHPDPVDPRFISLAGQVGVHVELTPTDTPHIYQVTMIAP Mvan_2180|M.vanbaalenii_PYR-1 AG------EPLPHPDPVDPRFVALAGDGGVHVELTPAEHSHIYNVTMIAP MSMEG_2427|M.smegmatis_MC2_155 AG------EPLPHPDPIDPRFLEIAADVGVHVELTPGDGQHIFNVTMIAP MAB_3238c|M.abscessus_ATCC_199 RG------EQLPEPDPIDPELLSLAADGGVQVRLVPAGSPHMYIVSLIAP TH_1479|M.thermoresistible__bu AG------EPLPHPDPIDPQHLSLAARGGVHVDLVPGDGPHIYQVTLVAP MLBr_01630|M.leprae_Br4923 AGRHTDPIRAIDAARSLRRRELARVGSADLLGLLEVTEVCKALTSVWVAV * . : . . : . .: : : * Mb2942c|M.bovis_AF2122/97 DERGLVS----------KAAAVLALNSLRVHSASVNVHQGVAITEFVVSP Rv2918c|M.tuberculosis_H37Rv DERGLVS----------KAAAVLALNSLRVHSASVNVHQGVAITEFVVSP MMAR_1789|M.marinum_M NKPGLVS----------KAAAVLALNSLGVHSAWVNSHEGVAITQFVVSP MAV_3773|M.avium_104 DQRGLVS----------KAAAVLALNSLRIHSASASTHEGFAVVEFVVSP Mflv_4183|M.gilvum_PYR-GCK DSRGVLS----------KAAGVMALNSLRVHSASVNGHEGSAINSFVVSP Mvan_2180|M.vanbaalenii_PYR-1 DSRGLLS----------KTAGVLALNSLRVHSASVNGHEGAAINTFVVSP MSMEG_2427|M.smegmatis_MC2_155 DRRGLLS----------KAAGVLALNSLRVHSASVNSHEGSAINTFVVSP MAB_3238c|M.abscessus_ATCC_199 DQRGLLS----------KAAGVLSLNSLRVFSASVASHAGSAINTFEVSP TH_1479|M.thermoresistible__bu DRRGLLS----------KAAGVLALNSLRVHSASVNSHHGSAINTFVVSP MLBr_01630|M.leprae_Br4923 LQAALDAVIRAYLPDGDKAPAAIAVIGMGRLGGAELGYGSDADVMFVCEP .: : *:...::: .: .. : . * * .* Mb2942c|M.bovis_AF2122/97 LFGSPPAAELVRQQFVGA----------LNGDVDVLGMLQKRDSD----- Rv2918c|M.tuberculosis_H37Rv LFGSPPAAELVRQQFVGA----------LNGDVDVLGMLQKRDSD----- MMAR_1789|M.marinum_M LFGTPAAADLLRQQFVGA----------LSGDIDALAMVEKRDSE----- MAV_3773|M.avium_104 LFGSPPEAGLLRQQFTGA----------LGGDVDVLGTLEKRDSD----- Mflv_4183|M.gilvum_PYR-GCK RFGTPPAAELLRQQLILA----------IDGELDVMGALEKKE------- Mvan_2180|M.vanbaalenii_PYR-1 RFGSPPAAELLRQQLILA----------IDGELDVMGALEKKE------- MSMEG_2427|M.smegmatis_MC2_155 HFGSPPAADLLRQQFVLA----------LDGDLDVIGSLERRERE----- MAB_3238c|M.abscessus_ATCC_199 RFGSPPAAGLLRQQLISA----------IDGDTDIIAALDERERE----- TH_1479|M.thermoresistible__bu HFGAPPAANLLRQQLILA----------LDGDLDVLAALERRDHDGAPGS MLBr_01630|M.leprae_Br4923 AIGVEDAQALRWSGMIAERVCRLLRTPSVDPPLDVDANLRPEGRNGPLVR :* * . : :. * . : . Mb2942c|M.bovis_AF2122/97 -------------------AASLVSARAGDVQAG---------------- Rv2918c|M.tuberculosis_H37Rv -------------------AASLVSARAGDVQAG---------------- MMAR_1789|M.marinum_M -------------------ATSNASQRAGEVVAG---------------- MAV_3773|M.avium_104 -------------------AVGAATRRAGEVQVG---------------- Mflv_4183|M.gilvum_PYR-GCK -------------------AESVATGRAGEVRAA---------------- Mvan_2180|M.vanbaalenii_PYR-1 -------------------AESTATGRAGEIRAA---------------- MSMEG_2427|M.smegmatis_MC2_155 -------------------AAQYPTTRAGEILAA---------------- MAB_3238c|M.abscessus_ATCC_199 -------------------SAQFATGVVGDAAPA---------------- TH_1479|M.thermoresistible__bu HR--------------PGEPAXXXVGVAAESIAAGLTAFEVGRHRAELIA MLBr_01630|M.leprae_Br4923 TLGAYAAYYAQWAQPWEIQALLRAHAVAGDADLG---------------- . ..: . Mb2942c|M.bovis_AF2122/97 -----------------VPVTRTAAPPRILWLDTAA-PAKLILEVRAMDR Rv2918c|M.tuberculosis_H37Rv -----------------VPVTRTAAPPRILWLDTAA-PAKLILEVRAMDR MMAR_1789|M.marinum_M -----------------VPVTRSTAPPRILWLDSAA-PDQLVLEVRSMDR MAV_3773|M.avium_104 -----------------VPVTRSTAPPRILWVDTAA-ADQLIVEVRAMDR Mflv_4183|M.gilvum_PYR-GCK -----------------VPINAPTAPPKVLWHEPSG-SGHVVAEIRATDR Mvan_2180|M.vanbaalenii_PYR-1 -----------------VPINPPTAPPRVLWHEGAG-AGQVVAEIRATDR MSMEG_2427|M.smegmatis_MC2_155 -----------------VPANHVPAPPRLLWADGSN-PGELIVQIRTIDR MAB_3238c|M.abscessus_ATCC_199 -----------------VPTNYAPAPPRIRWFEPAGNADQQIVEIRTSDA TH_1479|M.thermoresistible__bu TAGGISYVDDSKATNPHAAAASIAAHPRVVWIAGGLLKGAAVDELVAEVA MLBr_01630|M.leprae_Br4923 -------------QRFLLMADKMRYPPDGVSAEAVREIRRMKARVEAERL * .: : Mb2942c|M.bovis_AF2122/97 AG--------LLAL---------LAGALEGAGAGIVWAKVNT-------- Rv2918c|M.tuberculosis_H37Rv AG--------LLAL---------LAGALEGAGAGIVWAKVNT-------- MMAR_1789|M.marinum_M PG--------LLAL---------LTRALERAGADIVWAKVNT-------- MAV_3773|M.avium_104 LG--------LLAL---------LTRALERAGTDIVWAKVNT-------- Mflv_4183|M.gilvum_PYR-GCK TG--------LLAV---------LTRVFERAGVDIAWAKVTT-------- Mvan_2180|M.vanbaalenii_PYR-1 AG--------LLAV---------LTRVLERAGVDIAWAKVTT-------- MSMEG_2427|M.smegmatis_MC2_155 AG--------LLAR---------LTAVFERDGVDIAWAKVTT-------- MAB_3238c|M.abscessus_ATCC_199 PG--------LLAR---------ITATLERHGVDIAWAKVNT-------- TH_1479|M.thermoresistible__bu DR--------LAGXXLIGRDREIIAQALSRHAPEVPVVSVVTGDD----S MLBr_01630|M.leprae_Br4923 PRGADPHTHTKLGRGGLADIEWTVQLMQLRHAHELPALHKTSTLESLDAI . : . : : Mb2942c|M.bovis_AF2122/97 -----FGSTAADVFCVTVPAELD---ARAAVEQHLLEVLGASVDVVVDEP Rv2918c|M.tuberculosis_H37Rv -----FGSTAADVFCVTVPAELD---ARAAVEQHLLEVLGASVDVVVDEP MMAR_1789|M.marinum_M -----FGSTAADVFCVTVSAGLEEPQARAAMEQQLSAVLGGSADVLLDEP MAV_3773|M.avium_104 -----FGSTAADAFCVTA-GDAG---ARDAVEQSLLTVLGGPAVEVLEEP Mflv_4183|M.gilvum_PYR-GCK -----MGSSVIDVFGIVLPAG-EDA-VRESLEKQLLAVLPAPPQPKPVRE Mvan_2180|M.vanbaalenii_PYR-1 -----LGSSVVDAFGIVLPAD-GAA-ARQNLERELFAVLPAPP-AKPAEV MSMEG_2427|M.smegmatis_MC2_155 -----LGSSVVDAFGITTADGRTEQ-VRQELERDLYAVLPTPPPAKPAEQ MAB_3238c|M.abscessus_ATCC_199 -----LGSSVVDTFCLSTGPE------QAVLEAAIASVLPAVA-PQPKKA TH_1479|M.thermoresistible__bu GMQATAGAPVNAVTRVVEATEPIGP-AVMTAAVAAARALASPGDTVLLAP MLBr_01630|M.leprae_Br4923 AAANLIPEADVDLLRQAWLTATRARNALVLVRGKTTDQLPGPGRQLNAVA . * Mb2942c|M.bovis_AF2122/97 VGD------------------------------- Rv2918c|M.tuberculosis_H37Rv VGD------------------------------- MMAR_1789|M.marinum_M VGD------------------------------- MAV_3773|M.avium_104 VGD------------------------------- Mflv_4183|M.gilvum_PYR-GCK EAS------------------------------- Mvan_2180|M.vanbaalenii_PYR-1 EAS------------------------------- MSMEG_2427|M.smegmatis_MC2_155 AS-------------------------------- MAB_3238c|M.abscessus_ATCC_199 AAS------------------------------- TH_1479|M.thermoresistible__bu AGASFDQFSGYADRGDAFAAAVRAAIR------- MLBr_01630|M.leprae_Br4923 VAAGWPSDDGSEFLDNYLRVTRRAKTFVRKVFGS .