For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_2427 (glnD)

annotation: PII uridylyl-transferase
coordinates: 2510091 - 2512565
length: 824

MAEHKTQSAGASHKGAPAGSSRPANDLAAAVSQLLTGGPRQLDSAALRDALLDLYEFWLTTKATELGITA
DSGFAIVATGGLGRGEMLPYSDLDLMLLHDNMPVDVVTEVAEKLWYPLWDANIRLDHSVRTVPEALKVAG
EDISVGLAMLDVRHIAGDADLSSLLVGGARRQWRIGIASRFEELVEHAQARWQRSGQIAHRAEPDLKSGR
GGLRDVQLLNALAIAQLADVYPSRALASPTGTLGGAHLALLNVRTELHRVSGRGRELLLAQHADEIGAAL
RIGDRFDLARMLSDAARTVSYYVDSGIRTAANALPRRGFAALRRPVRRPLDEGVIEFAGEVILARDARPE
RDPGLVLRVAAASATTGLPIAVSTLSRLAETAPELRTPWPSQALKDLLVLLAAGPAAVATIEALDRTGLW
GRLFPEWGAVRDLPPRDVVHIWTVDRHLVETVSRASAFTTRVSRPDLLLLGALCHDIGKGRGGDHSVIGA
ELATQIGTRLGLWPSDIDVLSKLVRYHLLLPETATRRDLQDPKTIAAVVDALGGDMVVLELLDVLAEADS
LATGPGVWGDWKASLIGDLVRRCRLVMAGEPLPHPDPIDPRFLEIAADVGVHVELTPGDGQHIFNVTMIA
PDRRGLLSKAAGVLALNSLRVHSASVNSHEGSAINTFVVSPHFGSPPAADLLRQQFVLALDGDLDVIGSL
ERREREAAQYPTTRAGEILAAVPANHVPAPPRLLWADGSNPGELIVQIRTIDRAGLLARLTAVFERDGVD
IAWAKVTTLGSSVVDAFGITTADGRTEQVRQELERDLYAVLPTPPPAKPAEQAS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2427glnD-100% (824)PII uridylyl-transferase
M. smegmatis MC2 155MSMEG_6926-8e-0628.57% (203) tRNA adenylyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2942cglnD0.065.25% (774) PII uridylyl-transferase
M. gilvum PYR-GCKMflv_4183-0.081.56% (819) PII uridylyl-transferase
M. tuberculosis H37RvRv2918cglnD0.065.25% (774) PII uridylyl-transferase
M. leprae Br4923MLBr_02697pcnA9e-0529.05% (179) pcnA
M. abscessus ATCC 19977MAB_3238c-0.070.79% (801) PII uridylyl-transferase
M. marinum MMMAR_1789glnD0.063.90% (795) uridylyltransferase GlnD
M. avium 104MAV_3773glnD0.064.14% (792) PII uridylyl-transferase
M. thermoresistible (build 8)TH_1479glnD0.078.41% (718) PROBABLE
M. ulcerans Agy99MUL_5060pcnA7e-0529.19% (185) poly(a) polymerase PcnA
M. vanbaalenii PYR-1Mvan_2180-0.082.89% (824) PII uridylyl-transferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2942c|M.bovis_AF2122/97           MEAE-----------------SPCAASDLAVARRELLSGNHRELDPVGLR
Rv2918c|M.tuberculosis_H37Rv        MEAE-----------------SPCAASDLAVARRELLSGNHRELDPVGLR
MMAR_1789|M.marinum_M               MEPG-----------------SVRAASDLAAARRQLLSDDHRDMDPAELR
MAV_3773|M.avium_104                MTPTGP---------DPSGHQNACGAVDLAASRRQLLSEGG-KLHAAELR
Mflv_4183|M.gilvum_PYR-GCK          MKDSTSKPAAGASRWERPAAVSSRPATDLVAAAEQLLAGGARPLDSAALR
Mvan_2180|M.vanbaalenii_PYR-1       MKEQKSQPAAGAPRWERPAAGSLRPATDLVAAADQLLSG-SRQLDAAALR
MSMEG_2427|M.smegmatis_MC2_155      MAEHKTQSAG--ASHKGAPAGSSRPANDLAAAVSQLLTGGPRQLDSAALR
TH_1479|M.thermoresistible__bu      MTEQTPGPASGSFPAKDPEAVCSKPARDLVAATERLLAGGARQLDAASLR
MAB_3238c|M.abscessus_ATCC_199      ----------------------MGAATDLVAARAQLLGD-SGRLNAAAIR
MLBr_02697|M.leprae_Br4923          ----------------------------------MNVPEAAQDTDLLTVA
MUL_5060|M.ulcerans_Agy99           ------------------------------------MPETVQDADLLTAA
                                                                        :       .     

Mb2942c|M.bovis_AF2122/97           QTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSDLDVLLL
Rv2918c|M.tuberculosis_H37Rv        QTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSDLDVLLL
MMAR_1789|M.marinum_M               QAWLDLHESWLIAKAAQIGIADDSGYAIVGVGGLGRRELLPYSDLDLVLV
MAV_3773|M.avium_104                HAWLDLHESWLAAKAAQIGIADDSGFALVGIGGLGRHELLPYSDLDLMLL
Mflv_4183|M.gilvum_PYR-GCK          DALLDLHDFWLTTKATEIGITATSGFAIVATGGLGRGELLPYSDLDLMLL
Mvan_2180|M.vanbaalenii_PYR-1       DALLDLYDFWLTTKASEIGITATSGFAIVATGGLGRGELLPYSDLDLMLL
MSMEG_2427|M.smegmatis_MC2_155      DALLDLYEFWLTTKATELGITADSGFAIVATGGLGRGEMLPYSDLDLMLL
TH_1479|M.thermoresistible__bu      YALLDLHELWLNTKAAEIGITPVSGFSIVATGGLGRGELVPHSDLDLMLL
MAB_3238c|M.abscessus_ATCC_199      EAMTDLNELWLTTKAAEVGITDSSGFAIVALGGLGRREMLPYSDLDLVLL
MLBr_02697|M.leprae_Br4923          AVTLNRHTPVLRDLG---SVFAASGHELYLVGGSVRDALLGRLDSPDLDF
MUL_5060|M.ulcerans_Agy99           AVALNRHAAVLRELG---SAFADAGHDLYLVGGSVRDALLGRLKSPDLDF
                                     .  :     *   .   .    :*. :   **  *  ::   .   : .

Mb2942c|M.bovis_AF2122/97           HDG-KPADILRPVADRLWYPLWDANIRLDHSVRTVSEALTIANSDLMAAL
Rv2918c|M.tuberculosis_H37Rv        HDG-KPADILRPVADRLWYPLWDANIRLDHSVRTVSEALTIANSDLMAAL
MMAR_1789|M.marinum_M               HDG-KPVEELGDVADALWYPLWDANIRLDHSVRTVSDALGVAGADMAAAL
MAV_3773|M.avium_104                HDN-KSDEVLQRVADALWYPLWDANVRLDHSVRTVSGALGVANGDMIAAL
Mflv_4183|M.gilvum_PYR-GCK          HDN-MPAEIVGEVAELLWYPLWDANIRLDHSVRTVPEALRVAGEDISAGL
Mvan_2180|M.vanbaalenii_PYR-1       HDN-MPPEIVSEVAELLWYPLWDANIRLDHSVRTVPEALRVAGTDISAGL
MSMEG_2427|M.smegmatis_MC2_155      HDN-MPVDVVTEVAEKLWYPLWDANIRLDHSVRTVPEALKVAGEDISVGL
TH_1479|M.thermoresistible__bu      HDG-MPTELVGRIAEQLWYPLWDANIRIDHSVRTVAEALAVADADIAAGL
MAB_3238c|M.abscessus_ATCC_199      HDENIAPETLSEVADGLWYPLWDANIRLDHSVRTVADTLHVAGQEMSAAL
MLBr_02697|M.leprae_Br4923          ATD-AGPEQVQQIMRRWADNLWETGIEFGT--------------------
MUL_5060|M.ulcerans_Agy99           TTD-ARPQQILKIVRPWADAVWDTGIEFGT--------------------
                                           : :  :       :*::.:.:.                     

Mb2942c|M.bovis_AF2122/97           GMLEARHIAGDQQLSFALIDGVRRQWRNGIRSRMGELVEMTYARWRRCGR
Rv2918c|M.tuberculosis_H37Rv        GMLEARHIAGDQQLSFALIDGVRRQWRNGIRSRMGELVEMTYARWRRCGR
MMAR_1789|M.marinum_M               GMLEARHIVGDQQLSASLIDGVRRQWRSGIRSRMNELVDMTHDRWLRCGR
MAV_3773|M.avium_104                GMLDARHVAGDARLSDELIAGARRQWRSAIRSRMDELVEMTQARWDRCGR
Mflv_4183|M.gilvum_PYR-GCK          AMLEARHIAGDADLSSLLIGGARRQWRTGIAPRFEELVEHARARWQRSGE
Mvan_2180|M.vanbaalenii_PYR-1       AMLEARHIAGDGDLSSLLIGGARRQWRTGIASRFDELVEHTRARWQRSGE
MSMEG_2427|M.smegmatis_MC2_155      AMLDVRHIAGDADLSSLLVGGARRQWRIGIASRFEELVEHAQARWQRSGQ
TH_1479|M.thermoresistible__bu      AMLEARHIAGDADLSALVIDGARRHWRTTIASRFDELIDHTRARWERSGQ
MAB_3238c|M.abscessus_ATCC_199      ALLDARHIAGDAQLSSLMIGGVRQQWRSQIRTRLDELVEYTQARWRRSGE
MLBr_02697|M.leprae_Br4923          ------------------IGVGKGDYR----------LEITTFRADRYDQ
MUL_5060|M.ulcerans_Agy99           ------------------IGIAKNDYR----------LEITTFRADSYDQ
                                                      :   : .:*          :: :  *    ..

Mb2942c|M.bovis_AF2122/97           IAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHTDRPAGSLDGAY
Rv2918c|M.tuberculosis_H37Rv        IAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHTDLPAGSLDGAY
MMAR_1789|M.marinum_M               VANRAEPDLKSGRGGLRDVQLLDALAIAQLIDRHGLVTPDMPVGSLDAAY
MAV_3773|M.avium_104                IAQRAEPDLKSGRGGLRDVQLLDALGVAQLIDRHGMARPESPGGSLDDAH
Mflv_4183|M.gilvum_PYR-GCK          IAHRAEPDLKCGRGGLRDVQLLNALAIAQLADVYPSRSLASPTETLGEAN
Mvan_2180|M.vanbaalenii_PYR-1       IAHRAEPDLKCGRGGLRDVQLLNALAIAQLADVYPSRSLASPTETLGEAH
MSMEG_2427|M.smegmatis_MC2_155      IAHRAEPDLKSGRGGLRDVQLLNALAIAQLADVYPSRALASPTGTLGGAH
TH_1479|M.thermoresistible__bu      IAHRAEPDLKCGRGGLRDVQLLNALAIAQLADGYPSSSLASPTGTLGDAH
MAB_3238c|M.abscessus_ATCC_199      IAHRAEPDLKSGRGGLRDVQLLRALAIAQLTDSGLAKSFDG-------AH
MLBr_02697|M.leprae_Br4923          VSRNPE--------------------------------------------
MUL_5060|M.ulcerans_Agy99           VSRHPE--------------------------------------------
                                    ::...*                                            

Mb2942c|M.bovis_AF2122/97           RTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSAGR
Rv2918c|M.tuberculosis_H37Rv        RTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSAGR
MMAR_1789|M.marinum_M               LTLLNVRTELHRVSGRGRDLLLAQHADDISAALHFGDRFDLARMLSSAGR
MAV_3773|M.avium_104                LTLLDVRTELHRVSGRGLDQLLAQYGDELSAALHIGDRFDLARKLSDASR
Mflv_4183|M.gilvum_PYR-GCK          LALLNVRTELHRVAGRGRELLLAQHADEIGASLRIGDRFDLARTLSDAAR
Mvan_2180|M.vanbaalenii_PYR-1       LSLLNVRTELHRVAGRGRELLLAQHADEIGAALHIGDRFDLARMLSDAAR
MSMEG_2427|M.smegmatis_MC2_155      LALLNVRTELHRVSGRGRELLLAQHADEIGAALRIGDRFDLARMLSDAAR
TH_1479|M.thermoresistible__bu      LALLDVRTELHRIAGRGRDLLQAQYADEIAAALRIGDRFDLARLLSDAAR
MAB_3238c|M.abscessus_ATCC_199      SVILDVRTELHRVAGRERDQLLAQFADEIGAALRIGDRFDLARMLSDAAR
MLBr_02697|M.leprae_Br4923          --------------------------------VRFSDRLDDDLVRRDFTV
MUL_5060|M.ulcerans_Agy99           --------------------------------VRFGERLEDDLVRRDFTV
                                                                    : :.:*::      .   

Mb2942c|M.bovis_AF2122/97           TIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARD
Rv2918c|M.tuberculosis_H37Rv        TIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARD
MMAR_1789|M.marinum_M               TIAYHAESGLRTACNALPRRGISALRRRPKRRPLDEGVVECANEIVLARD
MAV_3773|M.avium_104                TIAYHAETGLRTAENALPRRGVSALVRRPKRRPLDEGVVEYAGEIVLARD
Mflv_4183|M.gilvum_PYR-GCK          TVSYYVDAGIRTAANSLPRRGLAAL-RRPVRRPLDEGVIEFAGEVILARD
Mvan_2180|M.vanbaalenii_PYR-1       TVSYYVDAGIRTAANALPRRGLAVL-RRPVRRPLDEGVIEFNGEVILARD
MSMEG_2427|M.smegmatis_MC2_155      TVSYYVDSGIRTAANALPRRGFAAL-RRPVRRPLDEGVIEFAGEVILARD
TH_1479|M.thermoresistible__bu      TVSYYVDSGLRTAANALPRRGFAAL-RRPLRRPLDEGVVEYAGEVILARD
MAB_3238c|M.abscessus_ATCC_199      TISYSVDVGLRAAANSIPRRGISAL-RRTVRRPIDEGVVEHAGEVVLARD
MLBr_02697|M.leprae_Br4923          NAMAVRIASYGPGEFFDPLGGLAALRVRVLETPAAP-------------S
MUL_5060|M.ulcerans_Agy99           NAMAVRITASGPGEFLDPLGGLSVLRDKVLDTPAAP-------------S
                                    .       .  ..    *  *.:.*  :    *                .

Mb2942c|M.bovis_AF2122/97           AEPEHDPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALDD
Rv2918c|M.tuberculosis_H37Rv        AEPEHDPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALDD
MMAR_1789|M.marinum_M               AQPEQDAGLVLRVAAAAAHAGLPIGAATLRRLADSAAELPTPWPREVLDD
MAV_3773|M.avium_104                ARPDTDVGLVLRVAAASASTGLPIGAATLSRLAAAAPEMPEPWPREALDD
Mflv_4183|M.gilvum_PYR-GCK          ARPERDPGLILRVAAASATTGLPIAGSTLSRLVEAAPELRTPWPRQALKD
Mvan_2180|M.vanbaalenii_PYR-1       ARPERDPGLILRVAAASATTGLPMAASTLSRLVEAAPELRTPWPGQALKD
MSMEG_2427|M.smegmatis_MC2_155      ARPERDPGLVLRVAAASATTGLPIAVSTLSRLAETAPELRTPWPSQALKD
TH_1479|M.thermoresistible__bu      ARPARDPGLILRVAAASATTGLPIAASTLSRLAATAPELRAPWPRPALND
MAB_3238c|M.abscessus_ATCC_199      ARPERDPSLILRVAAASATTGLPIAASTLARLAESAPELRTPWPREALKD
MLBr_02697|M.leprae_Br4923          VSFGDDPLRMLRAARFVSQLGFTVAPQVHAAIEEMASQLAR-ISAERVST
MUL_5060|M.ulcerans_Agy99           VSFGDDPLRMLRAARFVSQLGFAVAPRVRDAIEEMAPQLAR-ISAERVAA
                                    .    *   :**.*   :  *:.:.  .   :   ..::    .   :  

Mb2942c|M.bovis_AF2122/97           LLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVDR
Rv2918c|M.tuberculosis_H37Rv        LLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVDR
MMAR_1789|M.marinum_M               LLVVLLAGPTAVVTIEALDRTGLWGRLLPEWGAIRDLPPRDVAHKWTVDR
MAV_3773|M.avium_104                LLVLLSAGPTTVATIEALDRTGLWGRLLPEWDAIRDLPPRDVAHKWTVDR
Mflv_4183|M.gilvum_PYR-GCK          LLVMLAAGPSAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVDR
Mvan_2180|M.vanbaalenii_PYR-1       LLVMLAAGPSAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVDR
MSMEG_2427|M.smegmatis_MC2_155      LLVLLAAGPAAVATIEALDRTGLWGRLFPEWGAVRDLPPRDVVHIWTVDR
TH_1479|M.thermoresistible__bu      LLVLLGAGPAAVGTIEALDRTGLWGRLFPEWGAVRDLPPRDIVHVWTVDR
MAB_3238c|M.abscessus_ATCC_199      LLVLLESGRPALATIEALDRTGLWGRLFPEWGPVRDLPPRDIVHIWTVDR
MLBr_02697|M.leprae_Br4923          ELDKLLLGNDPAAGIDLLVQTGMGEVVLPEIGDMR-MAIDEHHQHKDVYQ
MUL_5060|M.ulcerans_Agy99           ELDKLLLGEDPVAGIDLMVHTGMGEVVLPEIGGMQ-MAIDEHHQHKDVYQ
                                     *  *  *  .   *: : :**:   ::**   :: :.  :  :   * :

Mb2942c|M.bovis_AF2122/97           HVVETAVHAAPLATRVARPDLLALGALLHDIGKGRGTDHSVLGAELVIPV
Rv2918c|M.tuberculosis_H37Rv        HVVETAVHAAPLATRVARPDLLALGALLHDIGKGRGTDHSVLGAELVIPV
MMAR_1789|M.marinum_M               HLIETAVQAAPLTTQVARPDLLALGALLHDIGKGRGADHSVLGAEMVVAI
MAV_3773|M.avium_104                HVIETTVNAAPLATRVARPDLLALGALLHDIGKGRGVDHSVLGAGLALEI
Mflv_4183|M.gilvum_PYR-GCK          HLVETVSRASAFTTRVSRPDLLLLGALVHDIGKGRGGDHSVIGAELAHQI
Mvan_2180|M.vanbaalenii_PYR-1       HLVETVSRASAFTTRVSRPDLLILGALVHDIGKGRGGDHSVIGAELADQI
MSMEG_2427|M.smegmatis_MC2_155      HLVETVSRASAFTTRVSRPDLLLLGALCHDIGKGRGGDHSVIGAELATQI
TH_1479|M.thermoresistible__bu      HLTETVAQASALTTRVSRPDLLLLGALLHDIGKGRGGDHSVIGAELAAQI
MAB_3238c|M.abscessus_ATCC_199      HLVETVVQASAFTTRVSRPDLLVLGALVHDIGKGRGGDHSVVGADLAVQI
MLBr_02697|M.leprae_Br4923          HSLTVLRQAIALEDNGPD-LVLRWAALLHDIGKPATRRHELNG-------
MUL_5060|M.ulcerans_Agy99           HSLTVLRQAIELEDEGPD-LALRWAALLHDIGKPATRRHEANG-------
                                    *   .  .*  :  . .    *  .** *****     *.  *       

Mb2942c|M.bovis_AF2122/97           CTRLGLSPPDVWTLSKLVRHHLLLPITATRRDLNDPKTIEAVSEALGGDP
Rv2918c|M.tuberculosis_H37Rv        CTRLGLSPPDVRTLSKLVRHHLLLPITATRRDLNDPKTIEAVSEALGGDP
MMAR_1789|M.marinum_M               GQRLGISAPDIDLLSKLVRHHLLLPVVATRSDLNDPSTITRVSEALGGDP
MAV_3773|M.avium_104                GPRLGMAPADVELLAQLVRHHLLLPVAATRSDLNDPKTIERVSKTLGEDP
Mflv_4183|M.gilvum_PYR-GCK          GSRLGLWPSDIKILAQVVRYHLLLPHTATRRDLQDAATISAVVDALDGDP
Mvan_2180|M.vanbaalenii_PYR-1       GSRLGLWPSDIRVLSTLVRHHLLLPHTATRRDLQDPATIAAVVDALDGDL
MSMEG_2427|M.smegmatis_MC2_155      GTRLGLWPSDIDVLSKLVRYHLLLPETATRRDLQDPKTIAAVVDALGGDM
TH_1479|M.thermoresistible__bu      GARLGLWPSDIDILVKLVRHHLLLVRTATRRDLDDPRTIESVVDALGPDP
MAB_3238c|M.abscessus_ATCC_199      GTRLGLWPSDVELLSKIVRYHLLLPNTATRRDLADPETIDGVVNTLGGDL
MLBr_02697|M.leprae_Br4923          --------------GVSFHHHEVVGAKMVRKRMRALKYAKQLVDDVSQLV
MUL_5060|M.ulcerans_Agy99           --------------GVSFHHHEVVGAKMVRNRMRALKYSKQMVDDVSQLV
                                                     .::* ::    .*  :        : . :.   

Mb2942c|M.bovis_AF2122/97           QLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVMAGESLPQAE
Rv2918c|M.tuberculosis_H37Rv        QLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVMAGESLPQAE
MMAR_1789|M.marinum_M               QLLEVLRALTEADSKATGPGVWSDWKASLVDDLVSRCRLAMAGEPLPRAD
MAV_3773|M.avium_104                LLLEVLHALTEADSKATGPGVWSDWKASLIDDLVRRCRMVMAGEPLPKVE
Mflv_4183|M.gilvum_PYR-GCK          AVLELLHVLAEADSLATGPGVWGDWKASLLGELVRRCRMVMAGEPLPHPD
Mvan_2180|M.vanbaalenii_PYR-1       VVLELLHVLAEADSLATGPGVWGDWKASLIGELVRRCRLVMAGEPLPHPD
MSMEG_2427|M.smegmatis_MC2_155      VVLELLDVLAEADSLATGPGVWGDWKASLIGDLVRRCRLVMAGEPLPHPD
TH_1479|M.thermoresistible__bu      VLLDLLHALVEADSLATGPGVWGEWKAALIGDLVRRCRLVMAGEPLPHPD
MAB_3238c|M.abscessus_ATCC_199      LLLELLQQLAEADSLATGPGVWGDWKASLIGELVRKCRLVMRGEQLPEPD
MLBr_02697|M.leprae_Br4923          YLHLRFHGYGEGKWTDSAVRRYVTDAGPLLSRLHKLVRADCTTRNQRRAA
MUL_5060|M.ulcerans_Agy99           YLHLRFHGYGDGKWTDSAVRRYVTDAGPLLARLHKLVRADCTTRNKRRAA
                                     :   :    :..   :.   :    ..*:  *    *     .   .  

Mb2942c|M.bovis_AF2122/97           PTAPHYLSLAADHGVHVEISPRDGERI-DAVIVAPDERGLVSKAAAVLAL
Rv2918c|M.tuberculosis_H37Rv        PTAPHYLSLAADHGVHVEISPRDGERI-DAVIVAPDERGLVSKAAAVLAL
MMAR_1789|M.marinum_M               PEAPHYVSLSADHGVHVEIAPGESARMYQVVMAAPNKPGLVSKAAAVLAL
MAV_3773|M.avium_104                PAAPQYLSLAADRGVHVQIKPGGGERL-DVVMAAPDQRGLVSKAAAVLAL
Mflv_4183|M.gilvum_PYR-GCK          PVDPRFISLAGQVGVHVELTPTDTPHIYQVTMIAPDSRGVLSKAAGVMAL
Mvan_2180|M.vanbaalenii_PYR-1       PVDPRFVALAGDGGVHVELTPAEHSHIYNVTMIAPDSRGLLSKTAGVLAL
MSMEG_2427|M.smegmatis_MC2_155      PIDPRFLEIAADVGVHVELTPGDGQHIFNVTMIAPDRRGLLSKAAGVLAL
TH_1479|M.thermoresistible__bu      PIDPQHLSLAARGGVHVDLVPGDGPHIYQVTLVAPDRRGLLSKAAGVLAL
MAB_3238c|M.abscessus_ATCC_199      PIDPELLSLAADGGVQVRLVPAGSPHMYIVSLIAPDQRGLLSKAAGVLSL
MLBr_02697|M.leprae_Br4923          RLQDSYDRLEAR-------------------------------IAELAAE
MUL_5060|M.ulcerans_Agy99           RLQSSYDRLEER-------------------------------ITELAAQ
                                            :                                   : : : 

Mb2942c|M.bovis_AF2122/97           NSLRVHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDV
Rv2918c|M.tuberculosis_H37Rv        NSLRVHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDV
MMAR_1789|M.marinum_M               NSLGVHSAWVNSHEGVAITQFVVSPLFGTPAAADLLRQQFVGALSGDIDA
MAV_3773|M.avium_104                NSLRIHSASASTHEGFAVVEFVVSPLFGSPPEAGLLRQQFTGALGGDVDV
Mflv_4183|M.gilvum_PYR-GCK          NSLRVHSASVNGHEGSAINSFVVSPRFGTPPAAELLRQQLILAIDGELDV
Mvan_2180|M.vanbaalenii_PYR-1       NSLRVHSASVNGHEGAAINTFVVSPRFGSPPAAELLRQQLILAIDGELDV
MSMEG_2427|M.smegmatis_MC2_155      NSLRVHSASVNSHEGSAINTFVVSPHFGSPPAADLLRQQFVLALDGDLDV
TH_1479|M.thermoresistible__bu      NSLRVHSASVNSHHGSAINTFVVSPHFGAPPAANLLRQQLILALDGDLDV
MAB_3238c|M.abscessus_ATCC_199      NSLRVFSASVASHAGSAINTFEVSPRFGSPPAAGLLRQQLISAIDGDTDI
MLBr_02697|M.leprae_Br4923          EDLARVRPDLDGNQIMALLDIPAGPQVG-----EAWRFLKELRLD-----
MUL_5060|M.ulcerans_Agy99           EDLDRVRPDLDGNQIMTLLDIPAGPQVG-----EAWRYLKELRLE-----
                                    :.*    .    :   ::  : ..* .*        *      :      

Mb2942c|M.bovis_AF2122/97           LGMLQKRDSD----------AASLVSARAGDVQAG---------------
Rv2918c|M.tuberculosis_H37Rv        LGMLQKRDSD----------AASLVSARAGDVQAG---------------
MMAR_1789|M.marinum_M               LAMVEKRDSE----------ATSNASQRAGEVVAG---------------
MAV_3773|M.avium_104                LGTLEKRDSD----------AVGAATRRAGEVQVG---------------
Mflv_4183|M.gilvum_PYR-GCK          MGALEKKE------------AESVATGRAGEVRAA---------------
Mvan_2180|M.vanbaalenii_PYR-1       MGALEKKE------------AESTATGRAGEIRAA---------------
MSMEG_2427|M.smegmatis_MC2_155      IGSLERRERE----------AAQYPTTRAGEILAA---------------
TH_1479|M.thermoresistible__bu      LAALERRDHDGAPGSHRPGEPAXXXVGVAAESIAAGLTAFEVGRHRAELI
MAB_3238c|M.abscessus_ATCC_199      IAALDERERE----------SAQFATGVVGDAAPA---------------
MLBr_02697|M.leprae_Br4923          RGPLTNEEAT----------------------------------------
MUL_5060|M.ulcerans_Agy99           RGPLTIEEAK----------------------------------------
                                     . :  .:                                          

Mb2942c|M.bovis_AF2122/97           ------------------VPVTRTAAPPRILWLDT-----AAPAKLILEV
Rv2918c|M.tuberculosis_H37Rv        ------------------VPVTRTAAPPRILWLDT-----AAPAKLILEV
MMAR_1789|M.marinum_M               ------------------VPVTRSTAPPRILWLDS-----AAPDQLVLEV
MAV_3773|M.avium_104                ------------------VPVTRSTAPPRILWVDT-----AAADQLIVEV
Mflv_4183|M.gilvum_PYR-GCK          ------------------VPINAPTAPPKVLWHEP-----SGSGHVVAEI
Mvan_2180|M.vanbaalenii_PYR-1       ------------------VPINPPTAPPRVLWHEG-----AGAGQVVAEI
MSMEG_2427|M.smegmatis_MC2_155      ------------------VPANHVPAPPRLLWADG-----SNPGELIVQI
TH_1479|M.thermoresistible__bu      ATAGGISYVDDSKATNPHAAAASIAAHPRVVWIAGGLLKGAAVDELVAEV
MAB_3238c|M.abscessus_ATCC_199      ------------------VPTNYAPAPPRIRWFEP----AGNADQQIVEI
MLBr_02697|M.leprae_Br4923          -------------------------------------------AELLAWW
MUL_5060|M.ulcerans_Agy99           -------------------------------------------AELLSWW
                                                                                . :   

Mb2942c|M.bovis_AF2122/97           RAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST-----------
Rv2918c|M.tuberculosis_H37Rv        RAMDRAGLLA-----LLAGALEGAGAGIVWAKVNTFGST-----------
MMAR_1789|M.marinum_M               RSMDRPGLLA-----LLTRALERAGADIVWAKVNTFGST-----------
MAV_3773|M.avium_104                RAMDRLGLLA-----LLTRALERAGTDIVWAKVNTFGST-----------
Mflv_4183|M.gilvum_PYR-GCK          RATDRTGLLA-----VLTRVFERAGVDIAWAKVTTMGSS-----------
Mvan_2180|M.vanbaalenii_PYR-1       RATDRAGLLA-----VLTRVLERAGVDIAWAKVTTLGSS-----------
MSMEG_2427|M.smegmatis_MC2_155      RTIDRAGLLA-----RLTAVFERDGVDIAWAKVTTLGSS-----------
TH_1479|M.thermoresistible__bu      ADRLAGXXLIGRDREIIAQALSRHAPEVPVVSVVTGDDSGMQATAGAPVN
MAB_3238c|M.abscessus_ATCC_199      RTSDAPGLLA-----RITATLERHGVDIAWAKVNTLGSS-----------
MLBr_02697|M.leprae_Br4923          KTRQSQGLL-----------------------------------------
MUL_5060|M.ulcerans_Agy99           RSRGNP--------------------------------------------
                                                                                      

Mb2942c|M.bovis_AF2122/97           ----AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVGD-
Rv2918c|M.tuberculosis_H37Rv        ----AADVFCVTVPAELD---ARAA-VEQHLLEVLGASVDVVVDEPVGD-
MMAR_1789|M.marinum_M               ----AADVFCVTVSAGLEEPQARAA-MEQQLSAVLGGSADVLLDEPVGD-
MAV_3773|M.avium_104                ----AADAFCVTA-GDAG---ARDA-VEQSLLTVLGGPAVEVLEEPVGD-
Mflv_4183|M.gilvum_PYR-GCK          ----VIDVFGIVLPAG-EDAVRES--LEKQLLAVLPAPPQPKPVREEAS-
Mvan_2180|M.vanbaalenii_PYR-1       ----VVDAFGIVLPAD-GAAARQN--LERELFAVLPAPP-AKPAEVEAS-
MSMEG_2427|M.smegmatis_MC2_155      ----VVDAFGITTADGRTEQVRQE--LERDLYAVLPTPPPAKPAEQAS--
TH_1479|M.thermoresistible__bu      AVTRVVEATEPIGPAVMTAAVAAARALASPGDTVLLAPAGASFDQFSGYA
MAB_3238c|M.abscessus_ATCC_199      ----VVDTFCLSTGPE-QAVLEAA--IASVLPAVAPQPKKAAAS------
MLBr_02697|M.leprae_Br4923          --------------------------------------------------
MUL_5060|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mb2942c|M.bovis_AF2122/97           ---------------
Rv2918c|M.tuberculosis_H37Rv        ---------------
MMAR_1789|M.marinum_M               ---------------
MAV_3773|M.avium_104                ---------------
Mflv_4183|M.gilvum_PYR-GCK          ---------------
Mvan_2180|M.vanbaalenii_PYR-1       ---------------
MSMEG_2427|M.smegmatis_MC2_155      ---------------
TH_1479|M.thermoresistible__bu      DRGDAFAAAVRAAIR
MAB_3238c|M.abscessus_ATCC_199      ---------------
MLBr_02697|M.leprae_Br4923          ---------------
MUL_5060|M.ulcerans_Agy99           ---------------