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TVTTQSTRDDEPDTSADDEQTPEGAGPGDADVADAHTETEPADDDSDPDEPMTARGWRRRVLLGVVALVF AALLAVSGVLGWMTWKQHQLTQAGEQARQAAVTYAQVLTSIDSAKVDENFNQVLDGATGEFKDMYSESSM QLRQLLIDNKAASRGVVVESAIQSVEEGRVVVLLFVDQSVTNSAVPDPRIDRSRIKMTMEYVDGRWRAAK VELA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0004 | - | - | 100% (215) | hypothetical protein Mflv_0004 |
| M. gilvum PYR-GCK | Mflv_2107 | - | 6e-17 | 26.67% (210) | hypothetical protein Mflv_2107 |
| M. gilvum PYR-GCK | Mflv_2527 | - | 4e-16 | 26.29% (213) | hypothetical protein Mflv_2527 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2411c | - | 1e-37 | 45.98% (174) | hypothetical protein Mb2411c |
| M. tuberculosis H37Rv | Rv2390c | - | 5e-38 | 45.25% (179) | hypothetical protein Rv2390c |
| M. leprae Br4923 | MLBr_02614 | - | 1e-05 | 25.47% (106) | hypothetical protein MLBr_02614 |
| M. abscessus ATCC 19977 | MAB_1004c | - | 2e-52 | 47.03% (219) | hypothetical protein MAB_1004c |
| M. marinum M | MMAR_3870 | - | 6e-63 | 56.95% (223) | hypothetical protein MMAR_3870 |
| M. avium 104 | MAV_0108 | - | 6e-51 | 51.69% (207) | hypothetical protein MAV_0108 |
| M. smegmatis MC2 155 | MSMEG_1149 | - | 6e-61 | 59.09% (220) | hypothetical protein MSMEG_1149 |
| M. thermoresistible (build 8) | TH_0161 | - | 2e-59 | 54.46% (213) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3802 | - | 2e-62 | 56.50% (223) | hypothetical protein MUL_3802 |
| M. vanbaalenii PYR-1 | Mvan_0965 | - | 2e-69 | 62.33% (215) | hypothetical protein Mvan_0965 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2411c|M.bovis_AF2122/97 -------MAIFG---------------------RGHGASEPG--------
Rv2390c|M.tuberculosis_H37Rv -------MAIFG---------------------RGHGASEPG--------
MSMEG_1149|M.smegmatis_MC2_155 -------MKLKTDKRRDVFDEAVDDTEDAEVEALDVAESEDTATEPE--S
TH_0161|M.thermoresistible__bu -------VTLTDEDR-----DRTDRDETPEPESSEQVVTETSAEEAG--E
Mvan_0965|M.vanbaalenii_PYR-1 -------MSVT-----------TDRDLDD--EKTDGEEDTTSQEEPD--G
Mflv_0004|M.gilvum_PYR-GCK -------MTVT-----------TQSTRDDEPDTSADDEQTPEGAGPG--D
MMAR_3870|M.marinum_M MHVQRKEMIVVATTEK----DDETQSEEPAASSEDNQDTEDTSQTPD--I
MUL_3802|M.ulcerans_Agy99 -------MIVVATTEK----DDETQSEEPAASSEDNQDTEDTSQTPD--I
MAV_0108|M.avium_104 -------MTVT---------------------ADQERATADDVEQP----
MAB_1004c|M.abscessus_ATCC_199 ------MVTMTK--------EDVDSTNDADTDTADDKETVDSAAETDSEI
MLBr_02614|M.leprae_Br4923 -------MNWPK--------------------TPGTLAAMPDEEQTELPV
:
Mb2411c|M.bovis_AF2122/97 -----------------------GTGEPAETPGRGRLTRSVTGWVGAVAV
Rv2390c|M.tuberculosis_H37Rv -----------------------GTGEPAETPGRGRLTRSVIGWVGAVAV
MSMEG_1149|M.smegmatis_MC2_155 DEVTGPSGE-KPSDKP------SDEKPAATVTSPNQRRGVVLGVAAGILV
TH_0161|M.thermoresistible__bu TGETGETGETEKTGEP------GEPGPAARSRRAGWLR---VGAVTAVFV
Mvan_0965|M.vanbaalenii_PYR-1 TEDSAAEDQQPEDSAS------GDPGPEAGNRS--WRRRVLAGAIAAVTI
Mflv_0004|M.gilvum_PYR-GCK ADVADAHTETEPADDD------SDPDEPMTARG--WRRRVLLGVVALVFA
MMAR_3870|M.marinum_M EVDSVEHAEAESADDDEDNTLLADKREKTARPNRSWARYLRRGAMPLLLA
MUL_3802|M.ulcerans_Agy99 EVDSVEHAEAESADDDEDNTLLADKREKAARPNRSWARYLRRGAMPLLLA
MAV_0108|M.avium_104 -----PDDDRKATADR------TESQPKTAARQ--WKRYGRAALVVAVYA
MAB_1004c|M.abscessus_ATCC_199 AEDAASTDTDAASSADSDSETASSDEDGDAAKGASWVRYAALGAVAAIMV
MLBr_02614|M.leprae_Br4923 HKEFAG---------------IADYSDPGLSDGSVFSQYGIASTVLAVLS
. :
Mb2411c|M.bovis_AF2122/97 VVSLAGSGWCGWVLFEKHQTDVAAGQALQAARSYVVKLATMDCERIDHNM
Rv2390c|M.tuberculosis_H37Rv VVSLAGSGWCGWVLFEKHQTDVAAGQALQAARSYVVKLATMDCERIDHNM
MSMEG_1149|M.smegmatis_MC2_155 AALLGGGGFVGWQLWQTKQVIAAGNQARDAAVNYAQVLTSIDSNKVDENF
TH_0161|M.thermoresistible__bu V-LLGLCGFLGWQVWQQRQLDRAADEARQAAVEYARILTSIDADKVDENF
Mvan_0965|M.vanbaalenii_PYR-1 G-AVATAGYLGWLLWQQNQVSRAGEQAQAAAVQYAQILTSIDSAKVDENF
Mflv_0004|M.gilvum_PYR-GCK A-LLAVSGVLGWMTWKQHQLTQAGEQARQAAVTYAQVLTSIDSAKVDENF
MMAR_3870|M.marinum_M G-ALALSAFLGWQQWQQHQVKLAGQQAQQAAIAYAQVLTSIDSNNVDQNF
MUL_3802|M.ulcerans_Agy99 G-ALALSAFLDWQQWQQHQVKLAGQQAQQAAIAYAQVLTSIDSNNVDQNF
MAV_0108|M.avium_104 G-AFGLAGGLGWKLWDQRAVAQAGQAAQRTAVDYAQVLTSIDANQVDQNF
MAB_1004c|M.abscessus_ATCC_199 G-ALVFSGIFGWKVWQQHQIDAAGEQALAVAIPYTETLTSIDSNDIDESF
MLBr_02614|M.leprae_Br4923 AAAVVFGVVIWRAHHDNSAERAYLTHVMQTAFDWTGVLINMNTSNVDASL
. . . .* :. * .:: :* .:
Mb2411c|M.bovis_AF2122/97 RDILEGSTGEFKDKYGKSSAHLRQLLADNRVATHGTVVAASVKSATTN--
Rv2390c|M.tuberculosis_H37Rv RDILEGSTGEFKDKYGKSSAHLRQLLADNRVATHGTVVAASVKSATTN--
MSMEG_1149|M.smegmatis_MC2_155 DQVLAGATGEFKDMYSQSSMQLRQLLIENKATAHGVVVESAVQSATKN--
TH_0161|M.thermoresistible__bu AQVLDGATGEFRDMYSASSAQLRQLLIDNKASARGVVLESAVQSAGED--
Mvan_0965|M.vanbaalenii_PYR-1 DQVLDGATGEFKDMYSQSSVQLRQLLIDNKASAHGVVVDSAIQSESKD--
Mflv_0004|M.gilvum_PYR-GCK NQVLDGATGEFKDMYSESSMQLRQLLIDNKAASRGVVVESAIQSVEEG--
MMAR_3870|M.marinum_M RQVLDGATGEFKDMYTQSSVQLRQLLIDNKASAHGVVVDSAVASETVN--
MUL_3802|M.ulcerans_Agy99 RQVLDGATGEFKDMYTQSSVQLRQLLIDNKASAHGVVVDSAVASETVN--
MAV_0108|M.avium_104 AAVLGGATGEFKDTYTKASVQLRQLLIDNKATAHGTVVDSAIQSQSRN--
MAB_1004c|M.abscessus_ATCC_199 RKILNGATGDLKKDFTPASVQLRQLLLDNKAASHGKVVNSAIQYKSTN--
MLBr_02614|M.leprae_Br4923 QRLHAGTVGELNTDFDAAVQPYRKVVEKLQTQSRGQIEAVAIESVHHDLD
: *:.*::. : : *::: . :. ::* : :: .
Mb2411c|M.bovis_AF2122/97 -------------------KVVVLMFIDQSVSNRNSPTPQIDRSRIKVIM
Rv2390c|M.tuberculosis_H37Rv -------------------KVVVLMFIDQSVSNRNSPTPQIDRSRIKVIM
MSMEG_1149|M.smegmatis_MC2_155 -------------------KAVVLLFVDQSVQNTAVPDPRIDRSRIKMTM
TH_0161|M.thermoresistible__bu -------------------EVVVLLFIDQTVSNAHVPEPRIDRSRVKMTM
Mvan_0965|M.vanbaalenii_PYR-1 -------------------KVVVLLFVDQSVSNTSVPDPRIDRSRVKMTM
Mflv_0004|M.gilvum_PYR-GCK -------------------RVVVLLFVDQSVTNSAVPDPRIDRSRIKMTM
MMAR_3870|M.marinum_M -------------------KVVVLVFVDQTVTNMAVPDPRIDRSRIKMTM
MUL_3802|M.ulcerans_Agy99 -------------------KVVVLIFVDQTVTNMAVPDPRIDRSRIKMTM
MAV_0108|M.avium_104 -------------------RVVVLLMVDQTVSNTVRPDGRVDRSRMKITM
MAB_1004c|M.abscessus_ATCC_199 -------------------KVVLLMMVDQSITNTQRPDPRVDKSRMKITM
MLBr_02614|M.leprae_Br4923 TQPGVAHPVVTTKLLPPAARTDSVMLVATSVSENVGGKPTTVHWSLRLDV
.. :::: :: : : ::: :
Mb2411c|M.bovis_AF2122/97 DKVNGRWLASKVELL-
Rv2390c|M.tuberculosis_H37Rv DKVNGRWLASKVELL-
MSMEG_1149|M.smegmatis_MC2_155 EKVDGQWKASKVELP-
TH_0161|M.thermoresistible__bu RHVDGTWRASKVALP-
Mvan_0965|M.vanbaalenii_PYR-1 EYVDGRWRASKVELP-
Mflv_0004|M.gilvum_PYR-GCK EYVDGRWRAAKVELA-
MMAR_3870|M.marinum_M EKVDGRWLASKVQLL-
MUL_3802|M.ulcerans_Agy99 EKVDGRWLASKVQLL-
MAV_0108|M.avium_104 ENVGGRWLASKVELP-
MAB_1004c|M.abscessus_ATCC_199 EKIDGRWLASKLEYL-
MLBr_02614|M.leprae_Br4923 SDVDGKLMISHLESIR
:.* :::