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MSLVSVAPELVVTAVPDVARIGSSIGAPDTAAAARPTTSVLAAGADEVSADVVALFGWVAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2371 | PE_PGRS40 | - | 100% (61) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1450c | PE_PGRS27 | 9e-15 | 72.13% (61) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv0124 | PE_PGRS2 | 5e-14 | 69.64% (56) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2392 | PE_PGRS40 | 2e-28 | 100.00% (61) | PE-PGRS family protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3763 | - | 1e-13 | 70.18% (57) | PE-PGRS family protein |
| M. avium 104 | MAV_1346 | - | 5e-06 | 46.43% (56) | PE family protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0570 | - | 1e-11 | 60.71% (56) | PE_PGRS family protein |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2371|M.tuberculosis_H37Rv MSLVSVAPELVVTAVPDVARIGSSIGAPDTAAAARPTTSVLAAGADEVSA
Mb2392|M.bovis_AF2122/97 MSLVSVAPELVVTAVPDVARIGSSIGAPDTAAAARPTTSVLAAGADEVSA
MMAR_3763|M.marinum_M MSFVSVAPEAVATAASDLARIGSSIDAVN-AAAAGATTTVLAAGADEVSV
MUL_0570|M.ulcerans_Agy99 MSFVITAPEALTAAATDLASLGSTIGAAN-AAAVAPTTAVLAAGADEVSA
MAV_1346|M.avium_104 MSFVTTRPEALLAVASMLEGLGSSMDAQN-AAAAAPTTSIAPAAADEVSA
**:* . ** : :... : :**::.* : ***. .**:: .*.*****.
Rv2371|M.tuberculosis_H37Rv DVVALFGWVAR---------------------------------------
Mb2392|M.bovis_AF2122/97 DVVALFGWVAR---------------------------------------
MMAR_3763|M.marinum_M AIAALFGTHAQEYQAISTRISALNERFVALLTAGNNSYAASESASVSWLQ
MUL_0570|M.ulcerans_Agy99 AVAAMFDAQGQAYQLLSARAAAFHEQFLQALSGGGASYAAGEAAAVS---
MAV_1346|M.avium_104 LQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAANRVN--
.* *. .
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M AVEQDVLGLVNAPSQNWFGRPLIGNGADGVAGTGQAGGAGGILWGNGGAG
MUL_0570|M.ulcerans_Agy99 ----PLLDAINAPVLADTGRPLIGNGAN--------GGAAGWLIGNGGAG
MAV_1346|M.avium_104 ---------TSAAALQGLAPNVIPNAAP---------------AADPPPA
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GSGAVGQSGGAGGSAGLLGHGGAGGAGGQAGASGTGGVGGAGGAGGWLYG
MUL_0570|M.ulcerans_Agy99 GSGTPG------------------------TASVAGGNGGNGGAGGLLFG
MAV_1346|M.avium_104 GTTSLG---------------------------TSIGWAQNVGAAASDFI
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M NGGTGGVGGEGPVNGGVGGAGGRAWLLGAGGSGGAGGQGLGLNGGAGGAG
MUL_0570|M.ulcerans_Agy99 TGGAGGAGGTASS------------LVGA------------IPGGNGGYG
MAV_1346|M.avium_104 TLGEGQFAP--------------------------------VPGAAGIPN
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GNGGLFGIGGTGGAGGDSAGSGSAGAGGDGGHGGLWGRGGAGGIGGVNSD
MUL_0570|M.ulcerans_Agy99 GDGGLL-----------------------------FGRGGAGGAGGFGNN
MAV_1346|M.avium_104 FNPGLT---------------------------------AATTAG-----
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M SGDGGAGGGGGAGGRLFGSGGAGGAGGTGAVAGSGGDGGAGGAAVGLWGL
MUL_0570|M.ulcerans_Agy99 T-TGGIGGLGGAGG-LFGAGGDGGVGGFGTFAGNGGDGGTG-----LFAA
MAV_1346|M.avium_104 -PPAPAAPAAAAGAPVLASMGRGPSIGGLSVPPS-------------WAP
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GGHGGAGGDGAVGLAGGVGEAGGEGGSAGNGGAGGLGGWLIGSGGAGGLG
MUL_0570|M.ulcerans_Agy99 GGDSGAGGD-----------------------------------------
MAV_1346|M.avium_104 GGVAP---------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GVGGAGGAGGAGAAGIAPGSNGGNGGNGGVGGAGGVGGSGGQGGFLRFLG
MUL_0570|M.ulcerans_Agy99 SVGGADGG------------DGGNGGKAGLVGQG----------------
MAV_1346|M.avium_104 ---------------------AANATPAQLVGAG----------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GQGDGGAGGAGGAGGVAGDGGKGADAAAFSGAAGGNGGHGGDNGAGGAGG
MUL_0570|M.ulcerans_Agy99 --GDGGAGGNN------------------------NSGFG----------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M TGGAGSTVGAHGADGFSPITGGNGGDGGNGASGPAASAGVAGGAGGAGGD
MUL_0570|M.ulcerans_Agy99 ----------------------------------------TGGSGGKGGD
MAV_1346|M.avium_104 ---------------------------------------FTSAAPDTAPV
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GGLYGNGGAGGDGGNGVAGGQGADATAAGASGENGGDGGAGGMGGAGGMG
MUL_0570|M.ulcerans_Agy99 AVLIGNGGNGGNAGSGGVG---------------------PGIAGAAGIG
MAV_1346|M.avium_104 TAVPGGVPSMATAGRGGYG------------------------LGAPRYG
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GVLGGHGGAGGIGGVGATGGSGGLGATGAEGVTGGNLHGGDGGNGGKGGI
MUL_0570|M.ulcerans_Agy99 GLLIGEDGMAGLTP------------------------------------
MAV_1346|M.avium_104 -VKPTVMPKPAI--------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GGAGGDGGAGGKAQAAGFADGTEGVGGAGGEGGAGGVAGDGGKGADAAAF
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M SGAAGGNGGHGGDNGAGGAGGTGGAGSTVGAHGADGFSPITGGNGGDGGN
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GASGPAASAGVAGGAGGAGGDGGLYGNGGAGGDGGNGVAGGQGADATAAG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M ASGENGGDGGAGGMGGAGGMGGVLGGHGGAGGIGGVGATGGSGGLGATGA
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M EGVTGGNLHGGDGGNGGKGGIGGAGGDGGAGGKAQAAGFADGTEGAGGAG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GEGGAGGVAGDGGKGADAAAFSGAAGGNGGHGGDNGAGGAGGTGGAGSTV
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GAHGADGFSPTTGGNGGDGGSGGSGFQGVKGGAGGVGGDGGLYGNGGTGG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M TGGTGGIGFNGSTTIGGGNGGDGHTGLTGGDGGAGGKGGALAGHGGDGGT
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GGVGGTGGTGGSGGTGTSGIFSSANGGDGGNGGDGGTGGTGGVGGLGGQA
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M QAAGFADGTQGVGGAGGVGGTGGNAGNGGHGANADVGSGKAGGNGGDGGD
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M PGVGGIGGQGGAGSIAGVEGAAGVAPTSGGNGGDGGNGASGATGVNGGAG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GSGGDGGLYGNGGDGGDGGNGGKGQVGSTGPVAGSAGGTGGTGGTGGQGG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M AGGSGGALAGHGGDGGSGGDGGTGGTGGTGRNGANGITGADIDGGSGGKG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GNGGTGGAGGAGGQGGQAQAAGYSDGTQGVGGAGGDGGTAGIGGDGGDGA
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M NAVAGSGERGGDGGHGGDPGNAGAGGQAGAGPTSGGNGKAGSGVTTGGNG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GDGGDGGSGAIGVKGGAGGAGGDGGLYGNGGNGGDGGTGGKGTVGDSGAT
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M LSADGDRGGAGATGGVGGAGGDGGAKGGNGGLGGSGGTGGMGGTGGDGAH
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GADMASGSGANGGYGGYGGFGGVGGAGGTGGVGGQAHAAGFTDGATGAGG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M DGGQGGTGGLGAWGGNGGDGADGSISGPPQNGGKGGDGGGGGPGGLGGQG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GLSGDGSSTGAAGELGTFGNGGSGGNGGIGGNATGFNAPGTGGAGGNGGN
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M GAFGGSGGTGGRGGSSSVGTGGAGGDGGDGGMGFGGIGGGGGTGGQGGSG
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M VDAQGIGGAGNGGVGGNGGDGGDGWDAPGGQGGKGGQGGNGGDGSPPVPP
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv --------------------------------------------------
Mb2392|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3763|M.marinum_M FGGSSGGTGGTGGTGGAGGDRFVDTELVGIGGAGHGGVTGGGPTGPALVD
MUL_0570|M.ulcerans_Agy99 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv ---------------
Mb2392|M.bovis_AF2122/97 ---------------
MMAR_3763|M.marinum_M GGTGGAGGSGGTGAH
MUL_0570|M.ulcerans_Agy99 ---------------
MAV_1346|M.avium_104 ---------------