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M. bovis AF2122 / 97 Mb2392 (PE_PGRS40)

annotation: PE-PGRS family protein
coordinates: 2619824 - 2620009
length: 61

MSLVSVAPELVVTAVPDVARIGSSIGAPDTAAAARPTTSVLAAGADEVSADVVALFGWVAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2392PE_PGRS40-100% (61)PE-PGRS family protein
M. bovis AF2122 / 97Mb1487cPE_PGRS283e-1468.85% (61) PE-PGRS family protein
M. bovis AF2122 / 97Mb1485cPE_PGRS273e-1468.85% (61) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv2371PE_PGRS402e-28100.00% (61) PE-PGRS family protein
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_3763-1e-1370.18% (57) PE-PGRS family protein
M. avium 104MAV_1346-5e-0646.43% (56) PE family protein
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0570-1e-1160.71% (56) PE_PGRS family protein
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb2392|M.bovis_AF2122/97         MSLVSVAPELVVTAVPDVARIGSSIGAPDTAAAARPTTSVLAAGADEVSA
Rv2371|M.tuberculosis_H37Rv      MSLVSVAPELVVTAVPDVARIGSSIGAPDTAAAARPTTSVLAAGADEVSA
MMAR_3763|M.marinum_M            MSFVSVAPEAVATAASDLARIGSSIDAVN-AAAAGATTTVLAAGADEVSV
MUL_0570|M.ulcerans_Agy99        MSFVITAPEALTAAATDLASLGSTIGAAN-AAAVAPTTAVLAAGADEVSA
MAV_1346|M.avium_104             MSFVTTRPEALLAVASMLEGLGSSMDAQN-AAAAAPTTSIAPAAADEVSA
                                 **:* . ** : :... :  :**::.* : ***. .**:: .*.*****.

Mb2392|M.bovis_AF2122/97         DVVALFGWVAR---------------------------------------
Rv2371|M.tuberculosis_H37Rv      DVVALFGWVAR---------------------------------------
MMAR_3763|M.marinum_M            AIAALFGTHAQEYQAISTRISALNERFVALLTAGNNSYAASESASVSWLQ
MUL_0570|M.ulcerans_Agy99        AVAAMFDAQGQAYQLLSARAAAFHEQFLQALSGGGASYAAGEAAAVS---
MAV_1346|M.avium_104             LQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAANRVN--
                                   .* *.  .                                        

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            AVEQDVLGLVNAPSQNWFGRPLIGNGADGVAGTGQAGGAGGILWGNGGAG
MUL_0570|M.ulcerans_Agy99        ----PLLDAINAPVLADTGRPLIGNGAN--------GGAAGWLIGNGGAG
MAV_1346|M.avium_104             ---------TSAAALQGLAPNVIPNAAP---------------AADPPPA
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GSGAVGQSGGAGGSAGLLGHGGAGGAGGQAGASGTGGVGGAGGAGGWLYG
MUL_0570|M.ulcerans_Agy99        GSGTPG------------------------TASVAGGNGGNGGAGGLLFG
MAV_1346|M.avium_104             GTTSLG---------------------------TSIGWAQNVGAAASDFI
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            NGGTGGVGGEGPVNGGVGGAGGRAWLLGAGGSGGAGGQGLGLNGGAGGAG
MUL_0570|M.ulcerans_Agy99        TGGAGGAGGTASS------------LVGA------------IPGGNGGYG
MAV_1346|M.avium_104             TLGEGQFAP--------------------------------VPGAAGIPN
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GNGGLFGIGGTGGAGGDSAGSGSAGAGGDGGHGGLWGRGGAGGIGGVNSD
MUL_0570|M.ulcerans_Agy99        GDGGLL-----------------------------FGRGGAGGAGGFGNN
MAV_1346|M.avium_104             FNPGLT---------------------------------AATTAG-----
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            SGDGGAGGGGGAGGRLFGSGGAGGAGGTGAVAGSGGDGGAGGAAVGLWGL
MUL_0570|M.ulcerans_Agy99        T-TGGIGGLGGAGG-LFGAGGDGGVGGFGTFAGNGGDGGTG-----LFAA
MAV_1346|M.avium_104             -PPAPAAPAAAAGAPVLASMGRGPSIGGLSVPPS-------------WAP
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GGHGGAGGDGAVGLAGGVGEAGGEGGSAGNGGAGGLGGWLIGSGGAGGLG
MUL_0570|M.ulcerans_Agy99        GGDSGAGGD-----------------------------------------
MAV_1346|M.avium_104             GGVAP---------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GVGGAGGAGGAGAAGIAPGSNGGNGGNGGVGGAGGVGGSGGQGGFLRFLG
MUL_0570|M.ulcerans_Agy99        SVGGADGG------------DGGNGGKAGLVGQG----------------
MAV_1346|M.avium_104             ---------------------AANATPAQLVGAG----------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GQGDGGAGGAGGAGGVAGDGGKGADAAAFSGAAGGNGGHGGDNGAGGAGG
MUL_0570|M.ulcerans_Agy99        --GDGGAGGNN------------------------NSGFG----------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            TGGAGSTVGAHGADGFSPITGGNGGDGGNGASGPAASAGVAGGAGGAGGD
MUL_0570|M.ulcerans_Agy99        ----------------------------------------TGGSGGKGGD
MAV_1346|M.avium_104             ---------------------------------------FTSAAPDTAPV
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GGLYGNGGAGGDGGNGVAGGQGADATAAGASGENGGDGGAGGMGGAGGMG
MUL_0570|M.ulcerans_Agy99        AVLIGNGGNGGNAGSGGVG---------------------PGIAGAAGIG
MAV_1346|M.avium_104             TAVPGGVPSMATAGRGGYG------------------------LGAPRYG
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GVLGGHGGAGGIGGVGATGGSGGLGATGAEGVTGGNLHGGDGGNGGKGGI
MUL_0570|M.ulcerans_Agy99        GLLIGEDGMAGLTP------------------------------------
MAV_1346|M.avium_104             -VKPTVMPKPAI--------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GGAGGDGGAGGKAQAAGFADGTEGVGGAGGEGGAGGVAGDGGKGADAAAF
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            SGAAGGNGGHGGDNGAGGAGGTGGAGSTVGAHGADGFSPITGGNGGDGGN
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GASGPAASAGVAGGAGGAGGDGGLYGNGGAGGDGGNGVAGGQGADATAAG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            ASGENGGDGGAGGMGGAGGMGGVLGGHGGAGGIGGVGATGGSGGLGATGA
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            EGVTGGNLHGGDGGNGGKGGIGGAGGDGGAGGKAQAAGFADGTEGAGGAG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GEGGAGGVAGDGGKGADAAAFSGAAGGNGGHGGDNGAGGAGGTGGAGSTV
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GAHGADGFSPTTGGNGGDGGSGGSGFQGVKGGAGGVGGDGGLYGNGGTGG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            TGGTGGIGFNGSTTIGGGNGGDGHTGLTGGDGGAGGKGGALAGHGGDGGT
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GGVGGTGGTGGSGGTGTSGIFSSANGGDGGNGGDGGTGGTGGVGGLGGQA
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            QAAGFADGTQGVGGAGGVGGTGGNAGNGGHGANADVGSGKAGGNGGDGGD
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            PGVGGIGGQGGAGSIAGVEGAAGVAPTSGGNGGDGGNGASGATGVNGGAG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GSGGDGGLYGNGGDGGDGGNGGKGQVGSTGPVAGSAGGTGGTGGTGGQGG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            AGGSGGALAGHGGDGGSGGDGGTGGTGGTGRNGANGITGADIDGGSGGKG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GNGGTGGAGGAGGQGGQAQAAGYSDGTQGVGGAGGDGGTAGIGGDGGDGA
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            NAVAGSGERGGDGGHGGDPGNAGAGGQAGAGPTSGGNGKAGSGVTTGGNG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GDGGDGGSGAIGVKGGAGGAGGDGGLYGNGGNGGDGGTGGKGTVGDSGAT
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            LSADGDRGGAGATGGVGGAGGDGGAKGGNGGLGGSGGTGGMGGTGGDGAH
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GADMASGSGANGGYGGYGGFGGVGGAGGTGGVGGQAHAAGFTDGATGAGG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            DGGQGGTGGLGAWGGNGGDGADGSISGPPQNGGKGGDGGGGGPGGLGGQG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GLSGDGSSTGAAGELGTFGNGGSGGNGGIGGNATGFNAPGTGGAGGNGGN
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            GAFGGSGGTGGRGGSSSVGTGGAGGDGGDGGMGFGGIGGGGGTGGQGGSG
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            VDAQGIGGAGNGGVGGNGGDGGDGWDAPGGQGGKGGQGGNGGDGSPPVPP
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         --------------------------------------------------
Rv2371|M.tuberculosis_H37Rv      --------------------------------------------------
MMAR_3763|M.marinum_M            FGGSSGGTGGTGGTGGAGGDRFVDTELVGIGGAGHGGVTGGGPTGPALVD
MUL_0570|M.ulcerans_Agy99        --------------------------------------------------
MAV_1346|M.avium_104             --------------------------------------------------
                                                                                   

Mb2392|M.bovis_AF2122/97         ---------------
Rv2371|M.tuberculosis_H37Rv      ---------------
MMAR_3763|M.marinum_M            GGTGGAGGSGGTGAH
MUL_0570|M.ulcerans_Agy99        ---------------
MAV_1346|M.avium_104             ---------------