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MSFVSVAPEIVVAAATDLAGIGSAISAANAAAAAPTTAVLAAGADEVSAAIAALFSGHAQAYQALSAQAA AFHQQFVQTLAGGAGAYAAAEAQVEQQLLAAINAPTQALLGRPLIGNGADGAPGTGQAGGAGGILYGNGG NGGSGAAGQAGGAGGPAGLIGHGGSGGAGGSGAAGGAGGHGGWLWGNGGVGGSGGAGVGAGVAGGHGGAG GAAGLWGAGGGGGNGGNGADANIVSGGDGGLGGAGGGGGWLYGDGGAGGHGGQGAIGLGGGAGGDGGQGG AGRGLWGTGGAGGHGGQGGGTGGPPLPGQAGMGAAGGAGGLIGNGGAGGDGGVGASGGVAGVGGAGGNAM LIGHGGAGGAGGDSSFANGAAGGAGGAGGHLFGNGGSGGHGGAVTAGNTGIGGAGGVGGDARLIGHGGAG GAGGDRAGALVGRDGGPGGNGGAGGQLYGNGGDGAPGTGGTLQAAVSGLVTALFGAPGQPGDTGQPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0124 | PE_PGRS2 | - | 100% (487) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1396c | PE_PGRS25 | 0.0 | 69.70% (495) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv0532 | PE_PGRS6 | e-153 | 58.39% (548) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0129 | PE_PGRS2 | 0.0 | 91.97% (498) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-85 | 43.35% (489) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 4e-15 | 42.70% (89) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-38 | 36.01% (361) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4223 | - | 1e-150 | 58.71% (511) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 1e-23 | 44.19% (172) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-65 | 41.63% (442) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 7e-39 | 39.79% (289) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1145 | - | 1e-140 | 55.58% (529) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 3e-83 | 47.38% (401) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0124|M.tuberculosis_H37Rv --------------------------------------------------
Mb0129|M.bovis_AF2122/97 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MMAR_4223|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0124|M.tuberculosis_H37Rv --------------------------------------------------
Mb0129|M.bovis_AF2122/97 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MMAR_4223|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0124|M.tuberculosis_H37Rv ---------------------------------------MSFVSVAP---
Mb0129|M.bovis_AF2122/97 ---------------------------------------MSFVSVAP---
MUL_1145|M.ulcerans_Agy99 ---------------------------------------MSYVVASP---
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MMAR_4223|M.marinum_M ---------------------------------------MSYLVAVP---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAP--
Rv0124|M.tuberculosis_H37Rv ----------------------------------------EIVVAAATDL
Mb0129|M.bovis_AF2122/97 ----------------------------------------EIVVAAATDL
MUL_1145|M.ulcerans_Agy99 ----------------------------------------EYVAAAASDL
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MMAR_4223|M.marinum_M ----------------------------------------EMLASAALDL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VEAASYVADPEAAL
MAV_4827|M.avium_104 ----------------------------------------SSIQ--MVVL
Rv0124|M.tuberculosis_H37Rv AG----------------------IGSAIS-----------AANAAAAAP
Mb0129|M.bovis_AF2122/97 AG----------------------IGSAIS-----------AANAAAAAP
MUL_1145|M.ulcerans_Agy99 AG----------------------IGSALS-----------TANAAAAAP
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MMAR_4223|M.marinum_M DN----------------------IGSTIT-----------AANAAAAAP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ANAG----------------LSAVSAAQVG---------AVMPVVAESVA
MAV_4827|M.avium_104 EG-----------------------EYADG-----------ATVEEDAID
Rv0124|M.tuberculosis_H37Rv TT-------AVLAAGADEVSAAIAALFSGHAQAYQALSAQAAAFHQQFVQ
Mb0129|M.bovis_AF2122/97 TT-------AVLAAGADEVSAAIAALFSGHAQAYQALSAQAAAFHQQFVQ
MUL_1145|M.ulcerans_Agy99 TI-------EVLAAGADEVSAAIAAFFGAHAQAYQALSEQASAFHLQFVQ
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MMAR_4223|M.marinum_M TT-------AVLAAGADEISAAVAALFTGHAQAYQWLGAQAGAFHSQFIQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFL
MAV_4827|M.avium_104 VTG---ADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEA
Rv0124|M.tuberculosis_H37Rv TLAGGAG--------AYAAAEAQVEQQLLAAIN-------APTQALLGRP
Mb0129|M.bovis_AF2122/97 TLAGGAG--------AYAAAEAQVEQQLLAAIN-------APTQALLGRP
MUL_1145|M.ulcerans_Agy99 AMTAGAG--------AYAGAEAVNASPLQAALDVLN----APAQALFGRP
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLGGN-------------GGHGGGTG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MMAR_4223|M.marinum_M ALTGSG--------IAYAGAEAANASPLQTAAQELLAVINTPTQTLLGRP
MLBr_01183|M.leprae_Br4923 ------------------------------------------MPLFLN--
MAB_4284c|M.abscessus_ATCC_199 SHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTT
MAV_4827|M.avium_104 AALRDALAARRIDNVMLVSAFLAAAALAQNVGG-------AMGYERTAVL
Rv0124|M.tuberculosis_H37Rv LIGN---------------GADGAPGTGQAGGAGG-------------IL
Mb0129|M.bovis_AF2122/97 LIGN---------------GADGAPGTGQAGGAGG-------------IL
MUL_1145|M.ulcerans_Agy99 LIGD---------------GAGGAP--GQSGGDGG-------------LL
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MMAR_4223|M.marinum_M LIGN------------------GADGAPGQAGGDG------------GLL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AIGD---------------GAVAVGGSNSGPIASG---------------
MAV_4827|M.avium_104 LVEP------------------DTATLAVVETSDG---------------
Rv0124|M.tuberculosis_H37Rv YGNGGNGGSGAAGQAGG---------------------------------
Mb0129|M.bovis_AF2122/97 YGNGGNGGSGAAGQAGG---------------------------------
MUL_1145|M.ulcerans_Agy99 YGNGGNGGNGGVGQAGG---------------------------------
TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MMAR_4223|M.marinum_M YGNGGNGGTSTTAGVAG---------------------------------
MLBr_01183|M.leprae_Br4923 --AEPQALTAAANTLEG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 QGSTAVNGDVRDSNIIN---------------------------------
MAV_4827|M.avium_104 -SIPDVYKQQIRAESYG---------------------------------
.
Rv0124|M.tuberculosis_H37Rv -------AGGPAGLIGHGGSGGAGGSG--------AA---GGAGGHGGWL
Mb0129|M.bovis_AF2122/97 -------AGGPAGLIGHGGSGGAGG--------------------HGGWL
MUL_1145|M.ulcerans_Agy99 -------AGGAAGLIGNGGSGGIGGPG--------TTGLAGGAGGSGGWL
TH_3810|M.thermoresistible__bu ----NGGNVGFFSLFNLGGAGGWGGSG-----------------------
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
MMAR_4223|M.marinum_M ------GDGGAAGLIGNGGAGGGGGAG-----------------------
MLBr_01183|M.leprae_Br4923 --------LSAATVASNAAAAQLT--------------------------
MAB_4284c|M.abscessus_ATCC_199 -----ADHGSNVGVDQSQTRVGGDYTN-----------------------
MAV_4827|M.avium_104 ------DAAGQLSAMVAGLEKLESLPG-----------------------
.
Rv0124|M.tuberculosis_H37Rv WG----------------------------------NGGVGGSGGAGVG-
Mb0129|M.bovis_AF2122/97 WG----------------------------------NGGVGGSGGAGVG-
MUL_1145|M.ulcerans_Agy99 FG----------------------------------NGGTGGRGGIGT--
TH_3810|M.thermoresistible__bu ---------------------------------------VDGVDVVG---
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
MMAR_4223|M.marinum_M --------------------------------------ALGGNGGAGG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------VSGHGSADIDK
MAV_4827|M.avium_104 ------------------------------------GLLLVGSGVDVAP-
Rv0124|M.tuberculosis_H37Rv --------------------------------------------------
Mb0129|M.bovis_AF2122/97 --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
MMAR_4223|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 S-------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0124|M.tuberculosis_H37Rv -------AGVAGGHGGAGGAAG---------------------LWGAGGG
Mb0129|M.bovis_AF2122/97 -------AGVAGGHGGAGGAAG---------------------LWGAGGG
MUL_1145|M.ulcerans_Agy99 -------TGIGGIGGTGGDAVG---------------------LFGHGGT
TH_3810|M.thermoresistible__bu -------------------------------------------GNPDGGT
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
MMAR_4223|M.marinum_M ------------------------------------------WLFGQGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------TEIAPP
MAB_4284c|M.abscessus_ATCC_199 ----VTVVDDHSQRNTTNINDS---------------------FNTDRST
MAV_4827|M.avium_104 ---------------------------------------LKQVLQTTTFL
Rv0124|M.tuberculosis_H37Rv GGNGGNGADANIVS------------------------------------
Mb0129|M.bovis_AF2122/97 GGNGGNGADANIVS------------------------------------
MUL_1145|M.ulcerans_Agy99 GGTGGNGPDIFIAGG-----------------------------------
TH_3810|M.thermoresistible__bu PGAHGESHTPGVYT------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
MMAR_4223|M.marinum_M GGNGGTATLAGGAG------------------------------------
MLBr_01183|M.leprae_Br4923 AADDVSILLAHFFS------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NIGSGNTTNTEIGSHN----------------------------------
MAV_4827|M.avium_104 DVSVAEEPETALARG-----------------------------------
Rv0124|M.tuberculosis_H37Rv -----------GGDGGLG-------GAGGGGGWLYGDGGAG---------
Mb0129|M.bovis_AF2122/97 -----------GGDGGLG-------GAGGGGGWLYGDGGAG---------
MUL_1145|M.ulcerans_Agy99 ----------AGGSGGTGGLLFGNGGAGGGAPWGGADGGAGGDARLIGNG
TH_3810|M.thermoresistible__bu ------------DRQGED-------GEDGTGTGIGGRGGNGG--------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAG-------GAGGTGG-TGGAGGTGG--------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNG-------GNGGTGG-TGGNGGTGG--------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDG-------GFNGTGGATGGRGGDGAGASVWKAN
MMAR_4223|M.marinum_M ------------GAGGVG-------GSAGLWG-TGGAGGNGG--------
MLBr_01183|M.leprae_Br4923 ------------GHGR----------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------QANIGTS-------TSAGGSAAVGGNAGLAG--------
MAV_4827|M.avium_104 -----------AALAAAN-----APLFASSTAALAYAQDPG---------
Rv0124|M.tuberculosis_H37Rv ---------------------------------GHGGQGAIGLGGGAGGD
Mb0129|M.bovis_AF2122/97 ---------------------------------GHGGQGAIGLGGGAGGD
MUL_1145|M.ulcerans_Agy99 GGGGYEGSLGVLSGGTAGPGGDGGNAVGLIGNGGAGGAGAAGLSGVTGGI
TH_3810|M.thermoresistible__bu --------------------------------SSSGTHPMAEDGEHVKAL
Mflv_5091|M.gilvum_PYR-GCK -------------------------TGGTGGIGGAGSTGGTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------TGGTGGIGGAGSTGGTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 GQHSTGQT----------------DTGGNGGRGGDGGTFVNAGANGNGGA
MMAR_4223|M.marinum_M --------------------------------FGALNLAGDGGAGAGGGD
MLBr_01183|M.leprae_Br4923 ------------------------------------QYQAHASQGATNHQ
MAB_4284c|M.abscessus_ATCC_199 ----------------------------NAGLAGNAGLAGNAGLAGNAGL
MAV_4827|M.avium_104 --------------------------------TGAVDQYSLPDYLYVPVD
Rv0124|M.tuberculosis_H37Rv GGQGGAGRGLWGTGGAGGHGGQG----GGTGGP-----------------
Mb0129|M.bovis_AF2122/97 GGQGGAGRGLWGTGGAGGHGGQG----GGTGGP-----------------
MUL_1145|M.ulcerans_Agy99 GGNGGNGAQLFGNGGAGGAGGQSQLASGGTGGSGGMAALFGNGGAGGAAG
TH_3810|M.thermoresistible__bu DGRPGLDGGNGSHGGNGGHGGRG--GFLGIGGSGGWG-------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTG-GTGGTGGTGGTGGKG--GTGGTGGAGGTG-------------
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTG-GTGGTGGTGGTGGKG--GTGGTGGDGGTG-------------
MSMEG_0868|M.smegmatis_MC2_155 GGAGGVSEGEGGTGGHGGDGGRG--GDGALGGNGGTGGV----------G
MMAR_4223|M.marinum_M GGRGGWLYGNGGVGGTGGTGGIG--LQGASGGDGGAG-------------
MLBr_01183|M.leprae_Br4923 DLIQSLLTSSSAYAGTETANHDS------L--------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG------------
MAV_4827|M.avium_104 PEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRR------------
. . .
Rv0124|M.tuberculosis_H37Rv -PLPGQAGMGAAGGAGG------LIGNGGAGGDGGVG------------A
Mb0129|M.bovis_AF2122/97 -PLPGQAGMGAAGGAGG------LIGNGGAGGDGGVG------------A
MUL_1145|M.ulcerans_Agy99 VSLSGAPGTGGNGGSAQ------FMGDGDSGGLGDSG------------G
TH_3810|M.thermoresistible__bu -------GHGGNGGD-----------TDADGGNGGDG-------------
Mflv_5091|M.gilvum_PYR-GCK -GDGGTGGTGGTGGTG---------GTGGTGGTGGAG-----------DG
Mvan_1264|M.vanbaalenii_PYR-1 -GTGGTGGTGGTGGTG---------GTGGTGGTGGAG-----------DG
MSMEG_0868|M.smegmatis_MC2_155 LGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTA
MMAR_4223|M.marinum_M -GGTGLWGTGGVGGNG---------GTGGIGLDGVAG-----------HI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --NAGLAGNAGLAGNAG--------LAGNAGLAGNAG-------------
MAV_4827|M.avium_104 -RPVLLVGSGLAVVGIS--------AVLALEIALAIG-----------IR
Rv0124|M.tuberculosis_H37Rv SGGVAGVG------------------------------------------
Mb0129|M.bovis_AF2122/97 SGGVAGVG------------------------------------------
MUL_1145|M.ulcerans_Agy99 SAGAAGAGGLIGNPLDVVNAPTEALLGRPLIGDGADGAPGESGQDGGLLY
TH_3810|M.thermoresistible__bu --GNGGSAG-----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGG-------------------------TGGQGGQGGQGG----
Mvan_1264|M.vanbaalenii_PYR-1 LGGTGGTGG-------------------------TGGFGGQGGQGG----
MSMEG_0868|M.smegmatis_MC2_155 TGGNGGNGGN---------------------GDADGHRGGKGGDGGEALI
MMAR_4223|M.marinum_M GGGNAGNAG-----------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAG-----------------------------------------
MAV_4827|M.avium_104 TTGTVALQP-----------------------------------------
Rv0124|M.tuberculosis_H37Rv ---------------GAGGNAMLIGHGGAGG-------------------
Mb0129|M.bovis_AF2122/97 ---------------GAGGNAMLIGHGGAGG-------------------
MUL_1145|M.ulcerans_Agy99 GNGGNGGNGLSGQAGGAGGAAGLIGNGGNGG-------------------
TH_3810|M.thermoresistible__bu -------------RGGTGGLRGVFGINGGNG-------------------
Mflv_5091|M.gilvum_PYR-GCK -------------TGGTGGQGG-LGGGGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGTGGQGG-LGGVGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155 RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG
MMAR_4223|M.marinum_M -------------NGGTGGSGGLLLGNGGDGGHG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------NAGLAGNAGLAGNAGLAG-------------------
MAV_4827|M.avium_104 ----------------TPNQHLIVPTEQAPAPPP----------------
Rv0124|M.tuberculosis_H37Rv -----AGG-DSSFANGAAGGAG----GAGGH-------------------
Mb0129|M.bovis_AF2122/97 -----AGG-DSSFANGAAGGAG----GAGGH-------------------
MUL_1145|M.ulcerans_Agy99 -----IGGPGTTGMSGGAGGAGGWLIGNGGHGGIGGLGIGIGDSGGAGGA
TH_3810|M.thermoresistible__bu -----RAGLGGRGXXXXGGGVG----AAVRSG------------------
Mflv_5091|M.gilvum_PYR-GCK ----GQGGTGGTGGQGGTGGTG----GTGGTG-----------------G
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGQGGTGGTG----GTGGTG-----------------G
MSMEG_0868|M.smegmatis_MC2_155 TATDGHGGSGINGGHGGNGGQG----TIEANGPS---------AVASGIG
MMAR_4223|M.marinum_M ----GTGGGGGRGINGADGGHG----GDGGTGG----------------A
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----NAGLAGNAAVAGNAAVAG---NAAVAGN---------------AA
MAV_4827|M.avium_104 ----VQASAPQPKISVPEPVAAPKPLSPPVAAPLP------------AAP
Rv0124|M.tuberculosis_H37Rv ------LFGNGGSGGHGG-----AVTAGNTGIGGAG--------------
Mb0129|M.bovis_AF2122/97 ------LFGNGGSGGHGG-----AVTAGNTGIGGAG--------------
MUL_1145|M.ulcerans_Agy99 GGAAIGLFGNGGTGGTGGYNQAFGAVSGVGGAGGAGGQWYGNGGDGGTSW
TH_3810|M.thermoresistible__bu ------NGVFSGGGGTPSA----GFGVPTTIQFPAGS-------------
Mflv_5091|M.gilvum_PYR-GCK TGGAGGDGGLGGLGGFGGS----GGTGGQGGLGGPGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGGAGGDGGLGGLGGFGGV----GGTGGQGGQGGPGG-------------
MSMEG_0868|M.smegmatis_MC2_155 AGGNGGDGIDGGLGGNGGD----GVVNTTANAANPGS-------------
MMAR_4223|M.marinum_M AGSAGLLFGDGGTGGHGGA----GFGGGNGSDSPQGG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGVLNTGVSGAIGGSSHVGG--AINESLGGSGSVGG-------------
MAV_4827|M.avium_104 PPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIP------------
Rv0124|M.tuberculosis_H37Rv -----GVGGDARLIGHGGAG--------------GAGGDRAGALVGRDG-
Mb0129|M.bovis_AF2122/97 -----GVGGDARLIGHGGAG--------------GAGGDRAGALVGRDG-
MUL_1145|M.ulcerans_Agy99 GGAAAGAGGDAGLIDNGGDGDSAGVLR---QNGIGGHGGAGGSLFGDGGD
TH_3810|M.thermoresistible__bu --CTSRAVSREGIMPSSRAAS--------------ARAGAACASSTSRSR
Mflv_5091|M.gilvum_PYR-GCK --STGGAGGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGK
Mvan_1264|M.vanbaalenii_PYR-1 --STGGAGGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGK
MSMEG_0868|M.smegmatis_MC2_155 --ATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGK
MMAR_4223|M.marinum_M --QGGNAGVAGNGGAGGSAAMLFGNG----------GAGGNGGSGGDGGH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---STAVGGGAHTGVGGGVSTGVGVG-------SHVGGGISESLGGSGSV
MAV_4827|M.avium_104 ---VPDPVSPPQLLAPPRLSVPQPVQP-------PVRVPQPPSPPQVGGT
Rv0124|M.tuberculosis_H37Rv -------------------GPGGNG------------GAGGQLYGNGGDG
Mb0129|M.bovis_AF2122/97 -------------------GPGGNG------------GAGGQLYGNGGDG
MUL_1145|M.ulcerans_Agy99 GGSAGFQSTAGDGGNAGLVGNGGNGGWAIYNSFAGDDGSGGTAIGNGGDG
TH_3810|M.thermoresistible__bu RSFCCSRA------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAQGATGAQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG
Mvan_1264|M.vanbaalenii_PYR-1 GAQGATGAQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAG
MMAR_4223|M.marinum_M GGNSTVSVPGGIG------GDAGAGGTGGSAGKSGLLFGAGGAGGQGGGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGG
MAV_4827|M.avium_104 VPQSPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVPTP
Rv0124|M.tuberculosis_H37Rv --------------------------------------------------
Mb0129|M.bovis_AF2122/97 GP--------------------GGQGGQAFGANNIGGTGGAGGNGGPAI-
MUL_1145|M.ulcerans_Agy99 GAN-------IVSSGFILGAGGGGNGGNAVGLIGNGGAGGTGADGFSTA-
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--
Mvan_1264|M.vanbaalenii_PYR-1 -----------TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--
MSMEG_0868|M.smegmatis_MC2_155 GFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSK
MMAR_4223|M.marinum_M G-----------TGGDGGNNIIGANVGGDGGAGGAGGLGGNGTDGGWLS-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 G----------AHTGVGGGVNTGVGVGSHVGGGISESLGGSGSVGGST--
MAV_4827|M.avium_104 G-----------------AGGSGGSGGGHVPTPGTGGPGGTGGSGGGHVP
Rv0124|M.tuberculosis_H37Rv ------------------------------------------APGTGG-T
Mb0129|M.bovis_AF2122/97 ------LSGNGGNGGAGGAGGAGGAGGGAGGVG-----GAGGAPGTGG-T
MUL_1145|M.ulcerans_Agy99 ------LGSDGGNGGTGAWLLGNGGAGGSGGST-----AGVHPAGDGGNS
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEG
Mvan_1264|M.vanbaalenii_PYR-1 ------AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEG
MSMEG_0868|M.smegmatis_MC2_155 IANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTG
MMAR_4223|M.marinum_M --------GNGGDGGAGGQG----GDGGHGG----------SPGGFDGKS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------AVGGGAHTSAINDALGGSGSVGG------------STAVGGG
MAV_4827|M.avium_104 ------TPGAGTPGGSGGGHLPFPGAGSTPGGS---------GGGHLPTP
Rv0124|M.tuberculosis_H37Rv LQAAVSG----------LVTALF---------------GAPGQPGDTGQP
Mb0129|M.bovis_AF2122/97 LQAAVSG----------LVTALF---------------GAPGQPGDTGQP
MUL_1145|M.ulcerans_Agy99 GMSALIGNGGAGGSAGVSPTGVFPSNGGSGGNAQLIGDGGDGGRGDSGGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGS
Mvan_1264|M.vanbaalenii_PYR-1 GAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGS
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGA
MMAR_4223|M.marinum_M GVGGDGGDGGN--------ARIIGNGGNGGNGGAGSTDGEGGQGGAAGLL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHA
MAV_4827|M.avium_104 GAGTPGGGLGG------FGGGHAPAPGGGLGGGGGHAPAPGGGLGGFGGG
Rv0124|M.tuberculosis_H37Rv G------------------
Mb0129|M.bovis_AF2122/97 G------------------
MUL_1145|M.ulcerans_Agy99 GGAGGTGGSLAGHDGSDGD
TH_3810|M.thermoresistible__bu -------------------
Mflv_5091|M.gilvum_PYR-GCK GGSGGSGGAAGDSDD----
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGSGGAAGDSD-----
MSMEG_0868|M.smegmatis_MC2_155 DGTPGTAGTTGANNP----
MMAR_4223|M.marinum_M FGQPGSMGT----------
MLBr_01183|M.leprae_Br4923 -------------------
MAB_4284c|M.abscessus_ATCC_199 SETAHTTLPGAEHH-----
MAV_4827|M.avium_104 HSGGGLGGLGGGHK-----