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PGRFRNFGSQNLGSGNIGSTNVGSGNIGSTNVGSGNIGDTNFGNGNNGNFNFGSGNTGSNNIGFGNTGSG NFGFGNTGNNNIGIGLTGDGQIGIGGLNSGSGNIGFGNSGTGNVGLFNSGTGNVGFGNSGTANTGFGNAG NVNTGFWNGGSTNTGLANAGAGNTGFFDAGNYNFGSLNAGNINSSFGNSGDGNSGFLNAGDVNSGVGNAG DVNTGLGNSGNINTGGFNPGTLNTGFFSAMTQAGPNSGFFNAGTGNSGFGHNDPAGSGNSGIQNSGFGNS GYVNTSTTSMFGGNSGVLNTGYGNSGFYNAAVNNTGIFVTGVMSSGFFNFGTGNSGLLVSGNGLSGFFKN LFG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2353c | PPE39 | - | 100% (354) | PPE FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv2356c | PPE40 | e-135 | 66.28% (344) | PPE family protein |
| M. tuberculosis H37Rv | Rv0755c | PPE12 | e-102 | 53.89% (386) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2377c | PPE40 | 1e-135 | 66.28% (344) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-22 | 31.72% (309) | triple helix repeat-containing collagen |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-21 | 35.31% (337) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_3665 | - | 1e-167 | 78.32% (346) | PPE family protein |
| M. avium 104 | MAV_4827 | - | 2e-07 | 27.44% (164) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 9e-24 | 32.43% (333) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 6e-13 | 26.97% (304) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0964 | - | 1e-110 | 57.85% (344) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 8e-25 | 31.82% (352) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------MSIIDFIL
MAV_4827|M.avium_104 --------------------------------------------------
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M ---------------------------------------------MNFAV
Mb2377c|M.bovis_AF2122/97 --------------------------------------------MVNFSV
MUL_0964|M.ulcerans_Agy99 ---------------------------------------------MNFMM
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGY
MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M LPPEINSVRMFSGAGSEPMLAAAA----------------------AWDG
Mb2377c|M.bovis_AF2122/97 LPPEINSGRMFFGAGSGPMLAAAA----------------------AWDG
MUL_0964|M.ulcerans_Agy99 LPPEVNSALMFTGAGSAPTLAAAT----------------------AWDG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 QSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDT
MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M LSAELGEAAESFASVTSGLAG-AGQAWQGAAASAMVAAAGPYASWLGAAA
Mb2377c|M.bovis_AF2122/97 LAAELGLAAESFGLVTSGLAGGSGQAWQGAAAAAMVVAAAPYAGWLAAAA
MUL_0964|M.ulcerans_Agy99 LVAELGEAAEAFSSVTSGLAS---GSWQGPAAAAMAAAAAPYAGWLSAAA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199 DFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG
MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M ARAAGASASAKVVASAFEAARAAMVHPLAVAANRN---------GFVQLV
Mb2377c|M.bovis_AF2122/97 ARAGGAAVQAKAVAGAFEAARAAMVDPVVVAANRS---------AFVQLV
MUL_0964|M.ulcerans_Agy99 TRALGAATQAKAAAAVFESAQAATVHPELVLANRN---------QLVSLV
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 AVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHG----------SNVG
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGS----------IPDVY
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M MSNLFGQNAPAIAAAEGVYEQMWAADVAAMAGYHGGASAAAAQLSSWQGM
Mb2377c|M.bovis_AF2122/97 LSNVFGQNAPAIAAAEATYEQMWAADVAAMVGYHGGAS-AAAALAPWQ--
MUL_0964|M.ulcerans_Agy99 LSNLFGQNAPAIAATESTYEELWAQDVAATVGYHGGASAVAAQLAPWQQA
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRS
MAV_4827|M.avium_104 KQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQ
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M VSGVLSGVPGVSGLVGGAAPAAAAVTTP----------LAGAAQAVASQA
Mb2377c|M.bovis_AF2122/97 -----QAVPGLSGLLGGAANAPAAAAQ-------------GAAQGLAELT
MUL_0964|M.ulcerans_Agy99 IQALPGRVAAMATTGPAASAAAALASGP----------AAALDIGNNGSG
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu --------NGYRTTDNNALDGGHGGNG-----------------GNVGFF
MAB_4284c|M.abscessus_ATCC_199 TNIGSGNTTNTEIGSHNQANIGTSTSAG----------GSAAVGGNAGLA
MAV_4827|M.avium_104 TTTFLDVSVAEEPETALARGAALAAANAP---------LFASSTAALAYA
Rv2353c|M.tuberculosis_H37Rv ---MPGRFR-----------------------------------------
MMAR_3665|M.marinum_M ASVVPAPLQGINL-------------------GFGNIGSLNLGSGNIGDG
Mb2377c|M.bovis_AF2122/97 LNLGVGNIGSLNL-------------------GSGNIGGTNVGSGNVGGT
MUL_0964|M.ulcerans_Agy99 NFLSIGNIGNNNL-------------------GSGNTGSANLGGGNIGNG
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu SLFNLGGAGGWG--------------------GSGVDG------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAG-------------------NAGLAGNAGLAGNAGLAG
MAV_4827|M.avium_104 QDPGTGAVDQYSLP------------------DYLYVPVDPEPGDDELAY
.
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M N--------LGSGNIGNINFGSGNIGGTNLGGGNQGDFNLGSGNIGNLNL
Mb2377c|M.bovis_AF2122/97 N--------LGSGNYGSLNWGSGNTGTGNAGSGNTGDYNPGS--------
MUL_0964|M.ulcerans_Agy99 N--------LGSGNTGNVNLGNGNNGFFNFGNGNLGDTNFGS--------
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu -----------VDVVGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 N----------AGLAGN---------------------------------
MAV_4827|M.avium_104 S---------AVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVG------
Rv2353c|M.tuberculosis_H37Rv ---NFGSQNLGSGN-IGSTNVGSGN---------------------IGST
MMAR_3665|M.marinum_M GSGNFGSQNLGSGN-IGSINFGVGN---------------------IGNT
Mb2377c|M.bovis_AF2122/97 --GNFGSGNFGSGN-IGSLNVGSGN---------------------FGTL
MUL_0964|M.ulcerans_Agy99 --GNSGNLNLGSGNRFGSGNIGFGNR--------------------FGDG
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu -------NPDGGTPG------------------------------AHGES
MAB_4284c|M.abscessus_ATCC_199 -AGLAGNAGLAGNAGLAGNAGLAGN----------------------AGL
MAV_4827|M.avium_104 ----SGLAVVGISAVLALEIALAIG------------------IRTTGTV
. .
Rv2353c|M.tuberculosis_H37Rv NVGSGNIGDTNFGN------------------------------------
MMAR_3665|M.marinum_M NIGSGNIGDTNFGS------------------------------------
Mb2377c|M.bovis_AF2122/97 NLANGNNGDVNFGG------------------------------------
MUL_0964|M.ulcerans_Agy99 NFGSGNAGSYNFGT------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu HTPGVYTDRQ----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAG------------------------------------
MAV_4827|M.avium_104 ALQPTPNQHLIVPT------------------------------------
Rv2353c|M.tuberculosis_H37Rv ---------------GNNGNFNFGSGNTGSNNIGFG--------------
MMAR_3665|M.marinum_M ---------------GNIGSLNFGSGNSGSNNIGFG--------------
Mb2377c|M.bovis_AF2122/97 ---------------GNTGDFNFGGGNNGTLNFGFG--------------
MUL_0964|M.ulcerans_Agy99 ---------------GNNGSFNIGSGNNGDSNIGFG--------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 ----------------NAGLAGNAGLAGNAGLAGNAG-------------
MAV_4827|M.avium_104 ---------------EQAPAPPPVQASAPQPKISVPEP------------
.
Rv2353c|M.tuberculosis_H37Rv NTGSGNFGFGNTGNNNIGIGLTGDGQIG-IGGLNSGSGNIG--FGNSGTG
MMAR_3665|M.marinum_M NFGSSNFGFGNTGNNNIGFGLTGDGQFG-IGGLNSGSGNIG--LFNSGDN
Mb2377c|M.bovis_AF2122/97 NTGSGNFGFGNTGNNNIGIGLTGDGQIG-IGGLNSGTGNIG--FGNSGNN
MUL_0964|M.ulcerans_Agy99 NLGTNNLGFGNNGSNNIGFGLSGSNQIG-IGGLNAGIGNMG--FGNAGDN
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGHG
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAG-NAAVGGVL
MAV_4827|M.avium_104 -VAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVP
. .
Rv2353c|M.tuberculosis_H37Rv NVGLFNSGTGNVGFGNSGTANTGFGNAGNVN---------TGFWNGGSTN
MMAR_3665|M.marinum_M NIGFFNSGSGNLGFGNAGNSNTGFGNAGDVN---------TGFWNGGSIN
Mb2377c|M.bovis_AF2122/97 NIGFFNSGDGNIGFFNSGDGNTGFGNAGNIN---------TGFWNAGNLN
MUL_0964|M.ulcerans_Agy99 NVGFFNSGSNNIGFFNSGDGNFGFAHAGSTN---------TGFWNSGGTN
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
TH_3810|M.thermoresistible__bu GRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGGNGG
MAB_4284c|M.abscessus_ATCC_199 NTGVSGAIGGSS--HVGGAINESLGGSGSVG---------GSTAVGGGAH
MAV_4827|M.avium_104 VPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPP------VRVPQPPSPPQ
. .
Rv2353c|M.tuberculosis_H37Rv TG--------------LANAGAGN----TGFFDAGNYNFG----------
MMAR_3665|M.marinum_M TG--------------VGHAGATN----FGFFDSGNYNAG----------
Mb2377c|M.bovis_AF2122/97 TG--------------FGSAGNGN----VGIFDGGNSNSG----------
MUL_0964|M.ulcerans_Agy99 TG--------------FGNGGSLN----FGFGNGGVENMG----------
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
TH_3810|M.thermoresistible__bu DG---------------GNGGSAG--------------------------
MAB_4284c|M.abscessus_ATCC_199 TG--------------VGGGVSTGVG--VGSHVGGGISES----------
MAV_4827|M.avium_104 VG---------------GTVPQSPPQ--HQTPPGEGTPPK----------
* .
Rv2353c|M.tuberculosis_H37Rv -------SLNAGNINSSFGNSGDGN-------------------------
MMAR_3665|M.marinum_M -------SFNAGNSNTSFGNSGDVN-------------------------
Mb2377c|M.bovis_AF2122/97 -------SFNVGFQNTGFGNSGAGN-------------------------
MUL_0964|M.ulcerans_Agy99 -------HGNAGSFNMGFGNGGGGN-------------------------
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
TH_3810|M.thermoresistible__bu -------RGGTGGLRGVFGINGGNG------------------------R
MAB_4284c|M.abscessus_ATCC_199 -------LGGSGSVGGSTAVGGGAH-------------------------
MAV_4827|M.avium_104 -------PDGPGNYGGGHVPTPGAG-------------------------
. *
Rv2353c|M.tuberculosis_H37Rv SGFLNAGDVNSGVGNAGDVNTG----------LGNSGNINTGGFNPGTLN
MMAR_3665|M.marinum_M TGFLNAGNINSGFGNAGNVNTG----------WANAGDINTGGFNGGVLN
Mb2377c|M.bovis_AF2122/97 TGFFNAGDSNTGFANAGNVNTG----------FFNGGDINTGGFNGGNVN
MUL_0964|M.ulcerans_Agy99 TGFYNSGTYNTGFSNAAETNTG----------WENSGNVNTGGYNSGGLN
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
TH_3810|M.thermoresistible__bu AGLGGRGXXXXGGGVGAAVRSG---------------NGVFSGGGGTPSA
MAB_4284c|M.abscessus_ATCC_199 --TGVGGGVSTGVGVGSHVGGG-----------ISESLGGSGSVGGSTAV
MAV_4827|M.avium_104 GSGGSGGGHVPTPGAGGSGGSG-------------GGHVPTPGTGGPGGT
* . . * . .
Rv2353c|M.tuberculosis_H37Rv TGFFSAMTQAGPNSGFFNAGTGNSGFGHNDPAGSGNSG------IQNSGF
MMAR_3665|M.marinum_M TGFFSATTHAGPNSGYFNVGTGNSGFGHNDPSGSGNSG------LQNSGF
Mb2377c|M.bovis_AF2122/97 TGFGSALTQAGANSGFGNLGTGNSGWGNSDPSGTGNSG------FFNTGN
MUL_0964|M.ulcerans_Agy99 TGIGSPDTQAGPNSGFGHSGSGNSGFFN---SGDGNSG------FENSNT
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
TH_3810|M.thermoresistible__bu GFGVPTTIQFPAGSCTSRAVSREG------------------------IM
MAB_4284c|M.abscessus_ATCC_199 GGGAHTGVGGGVNTGVGVGSHVGGGISESLGGSGSVGG-------STAVG
MAV_4827|M.avium_104 GGSGGGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGG---------GHL
Rv2353c|M.tuberculosis_H37Rv GNSGYVNTST-TSMFGGNSGVLNTG-------YGNSGFYNAAVNNTGIFV
MMAR_3665|M.marinum_M GNSGYVNTST-TSTFGGNSGALDTG-------YGNAGFYNAAVQNAGFVI
Mb2377c|M.bovis_AF2122/97 GNSGFSNAGP-AMLPGFNSGFANIG-------SFNAGIANSGNNLAGISN
MUL_0964|M.ulcerans_Agy99 CVSANGHSGVRNSGDATNVGFSNSG-------SNNTGIFNTGTFNTGIAN
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
TH_3810|M.thermoresistible__bu PSSRAASARAG---------------------------AACASSTSRSRR
MAB_4284c|M.abscessus_ATCC_199 GGAHTSAINDALGGSGSVGGSTAVG--------GGAHTSAINESMNSSIN
MAV_4827|M.avium_104 PTPGAGTPGGGLGGFGGGHAPAPGG-----------------GLGGGGGH
Rv2353c|M.tuberculosis_H37Rv TGVMSSGFFNFG------------------TGNSGLLVSGNGLSGFFKNL
MMAR_3665|M.marinum_M AGVNTSGILSSG------------------TGSSGLLVFGDGLSGFFKNV
Mb2377c|M.bovis_AF2122/97 SGDDSSGAVNSG------------------SQNSGAFNAGVGLSGFFR--
MUL_0964|M.ulcerans_Agy99 SGSDSSGLLISG------------------TNSSGALNSGDDQSGFNN--
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
TH_3810|M.thermoresistible__bu SFCCSRA-------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ASHSSSMNESFG----------------SSMGSHGAAGTGFEAQGHAQGH
MAV_4827|M.avium_104 APAPGGGLGGFG------------------GGHSGGGLGGLGGGHK----
:
Rv2353c|M.tuberculosis_H37Rv FG------------------------------------------------
MMAR_3665|M.marinum_M L-------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ASETAHTTLPGAEHH-----------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2353c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3665|M.marinum_M --------------------------------------------------
Mb2377c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv2353c|M.tuberculosis_H37Rv ---------------------------
MMAR_3665|M.marinum_M ---------------------------
Mb2377c|M.bovis_AF2122/97 ---------------------------
MUL_0964|M.ulcerans_Agy99 ---------------------------
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ---------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------
MAV_4827|M.avium_104 ---------------------------