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RSKIPDLQRALEGRFDDHHALMCRLHLAHLDQLDAMIGALDEQIEQLMHPFCARRELIASIPGIGVGASA TVISEIGADPAAWFPSAEHLASWVRLCPGNHESAGKRHHGARRTGNQHLQPVLVECAWAAVRTDGYLREY YRRQVRKFGGFRSPAANKKAIIAVAHKLIVIIWHVLATGRPYQDLGADYFTTRMDPDKERRRLVAKLEAQ GLGVTLEPAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2177c | - | - | 100% (221) | POSSIBLE TRANSPOSASE |
| M. tuberculosis H37Rv | Rv2424c | - | e-127 | 98.64% (221) | transposase |
| M. tuberculosis H37Rv | Rv2014 | - | 1e-08 | 25.12% (203) | transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2447c | - | 1e-129 | 100.00% (221) | transposase |
| M. gilvum PYR-GCK | Mflv_4200 | - | 2e-07 | 30.97% (155) | transposase IS116/IS110/IS902 family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3782 | - | 1e-05 | 25.81% (186) | transposase |
| M. avium 104 | MAV_0496 | - | 4e-05 | 29.56% (159) | transposase IS116/IS110/IS902 |
| M. smegmatis MC2 155 | MSMEG_4550 | - | 4e-07 | 30.32% (155) | transposase |
| M. thermoresistible (build 8) | TH_3017 | - | 1e-08 | 30.26% (152) | PUTATIVE transposase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4882 | - | 1e-42 | 43.05% (223) | transposase IS116/IS110/IS902 family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3782|M.marinum_M --------MPT--VWAGVDTGKRTHHCVVLDRNGGVLLSRPVDNDETALL
TH_3017|M.thermoresistible__bu ---------------------------VVIDAQGKRLLSQRVANDEATLL
Mflv_4200|M.gilvum_PYR-GCK --------MTTGQVWAGVDVGKEHHWVCAVDDSGKVVLSRRLVNDEQPIR
MSMEG_4550|M.smegmatis_MC2_155 --------MAAGQVWAGVDVGKEHHWVCVVDDSGKVVLSRRLVNDEQPIR
Rv2177c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2447c|M.bovis_AF2122/97 --------------------------------------------------
Mvan_4882|M.vanbaalenii_PYR-1 MLVESEDSEQIIARVAALDIGKAELVCCVRVPGRGTRRLQEVSTHSTMAR
MAV_0496|M.avium_104 -----------------------------------MVARGRVSNDAAGFA
MMAR_3782|M.marinum_M ELIEAVVGVAAGREVCWATDLNAGGAAMLITLLAAHDQQLLYIPGRIVHH
TH_3017|M.thermoresistible__bu KLISTVATMADGGEVTWAIDLNAGGAALLITLLIAADQRLLYIPGRTVHH
Mflv_4200|M.gilvum_PYR-GCK ELVAEIDELAER--VSWTVDLTTVYAALVLTVLADAGKTVRYLAGRAVWQ
MSMEG_4550|M.smegmatis_MC2_155 ELVAEIDELAER--VLWAVDLTTVYAALLLTVLADAGKTVRYLAGRAVWQ
Rv2177c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2447c|M.bovis_AF2122/97 --------------------------------------------------
Mvan_4882|M.vanbaalenii_PYR-1 SLTELANHLVESGVQRVVMEATSDYWKPVFYLLEAHGLDPWLVNARDVKH
MAV_0496|M.avium_104 ALLTLLAEAGDSAAHPIPVGIETDRG-LWVAALRETGRVIYPINPLAASR
MMAR_3782|M.marinum_M AAATYRG-DGKTDAKNARIIADQA---RMR-TDLQPVRRADPIATDLRLL
TH_3017|M.thermoresistible__bu ASGSYRG-EGKTDAKDAAVIADQA---RMR-RDLQPLRPGDDITVELRIL
Mflv_4200|M.gilvum_PYR-GCK ASATYRGGEAKTDAKDARVIADQA---RMRGQDLPVLHPDDDLISELRML
MSMEG_4550|M.smegmatis_MC2_155 ASATYRGGEAKTDAKDARVIADQS---RMRGQDLPVLHPNDDLISELRML
Rv2177c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2447c|M.bovis_AF2122/97 --------------------------------------------------
Mvan_4882|M.vanbaalenii_PYR-1 LPGRPKT-----DVLDAVWLAKLAERQ-----MLRPSFVPPPPIRQLRDL
MAV_0496|M.avium_104 YRARHAVSGAKSDATDAVLLANIVR---TDAAAHRPLPADTELAQAIRVL
MMAR_3782|M.marinum_M TSRRTDVVCDRVRAINRLRQTLLEYFPPLERAFDYSKS-----KAALTLL
TH_3017|M.thermoresistible__bu TSRRTDLVADRTRTINRLRAQLLEYFPALERAFDYSTS-----KAALLLL
Mflv_4200|M.gilvum_PYR-GCK TGHRADLVADRTRTINRLRQQLVAVCPALERAAQPSQD-----RGWVILL
MSMEG_4550|M.smegmatis_MC2_155 TGHRADLVADRTRTINRLRQQLVAVCPALERAAQLSQD-----RGWVVLL
Rv2177c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2447c|M.bovis_AF2122/97 --------------------------------------------------
Mvan_4882|M.vanbaalenii_PYR-1 TRYRIDLVATRTAERNRVEKLLEDACIKLSVVAS----------DIFGVS
MAV_0496|M.avium_104 ARAQQDAVWARQQIGNQIRDLLKDFYPAAIAAFAGLPEGGLARADARTIL
MMAR_3782|M.marinum_M SRYQTPDSLRRIGPTRLATWLKARGCRNSATVAQTAVQAAQTQHTTLPTQ
TH_3017|M.thermoresistible__bu TGYQTPDGLRRAGAARLAVWLGKRKARNADAVAAKALQAAHAQHTVIPGQ
Mflv_4200|M.gilvum_PYR-GCK ARYQRPKAIRQSGVSRLTKVLTDAGVRNAASIAAAAVAAVKTQTMRLPGE
MSMEG_4550|M.smegmatis_MC2_155 ARYQRPKAIRQSGVSRLTKVLTDAGVRNAASIAGAAVAAVKTQTVRLPGE
Rv2177c|M.tuberculosis_H37Rv -------------------------MRSKIPDLQRALEGRFDDHHAL---
Mb2447c|M.bovis_AF2122/97 ----------------MLADLARGSMRSKIPDLQRALEGRFDDHHAL---
Mvan_4882|M.vanbaalenii_PYR-1 GRAMMAALIAGERDPKVLAQLARSRMRTKIGRLEEAFNGHFNAHHGF---
MAV_0496|M.avium_104 AAAPTPTQAATLTPARLRRLLTKAGRRRHLDRDIERLRAVFTDTYLHQPP
* . .
MMAR_3782|M.marinum_M TVGAQLVPRLAAEITTIDAELAHVDNEITARFA---DHDSAEILTSMPGF
TH_3017|M.thermoresistible__bu QLAAAMVARLAKEVMALDTEIGDTDAMIEERFH---RHRHAEIIVSMSGF
Mflv_4200|M.gilvum_PYR-GCK EVAAGLIADLAREVIALDDRIKTTDADIEGRFR---RHPLAEVITSMPGI
MSMEG_4550|M.smegmatis_MC2_155 EVAAGLVADLAREVIALDDRIKTTDADIEGRFR---RHPLAEVITSMPGM
Rv2177c|M.tuberculosis_H37Rv -----MCRLHLAHLDQLDAMIGALDEQIEQLMHP--FCARRELIASIPGI
Mb2447c|M.bovis_AF2122/97 -----MCRLHLAHLDQLDAMIGALDEQIEQLMHP--FCARRELIASIPGI
Mvan_4882|M.vanbaalenii_PYR-1 -----LLTRMLARLDGIDADIAVLDEQIEVYLAP--FAAAAARLDEIPGI
MAV_0496|M.avium_104 AVENAMGIQLAALLRQLEAACTAADELAEAAIAHFEQHPDAKIITSFPGL
: : :: * : : .:.*:
MMAR_3782|M.marinum_M GPVLAATFLAQIGGNLDGFD-TVDRLACVAGLAPVPRDSGRISGNLHRPR
TH_3017|M.thermoresistible__bu GVTLGAEFLAATGGDMSAFD-SVDRLAGVAGLAPVPRDSGRISGNLQRPR
Mflv_4200|M.gilvum_PYR-GCK GFRLGAEFLAAVG-DPALIG-SADQLAAWAGLAPVSRDSGKRTGRLHTPK
MSMEG_4550|M.smegmatis_MC2_155 GFRLGAELLAAVG-DPALIG-SADQLAAWAGLAPVSRDSRKRTGRLHTPK
Rv2177c|M.tuberculosis_H37Rv GVGASATVISEIGADPAAWFPSAEHLASWVRLCPGNHESAGKRHHGARR-
Mb2447c|M.bovis_AF2122/97 GVGASATVISEIGADPAAWFPSAEHLASWVRLCPGNHESAGKRHHGARR-
Mvan_4882|M.vanbaalenii_PYR-1 GAVAAAIILAEIGTD-MSVFPTAGHLCSWAKFSPGIQSSAGKTKGTASTG
MAV_0496|M.avium_104 GMLAGARVLAEIGDDRTRFA-DARGLKAFAGSAPITRASGKKTVVLHRH-
* .* .:: * : . * . .* : *
MMAR_3782|M.marinum_M RFNRRLLRPCYLAALSSLKNSPASRTFYDRKRAEGK------SHKQALIA
TH_3017|M.thermoresistible__bu RYNRRLLRVCYLSALSSIRSDPASRTYYNRKRAEGK------RHSQAVLA
Mflv_4200|M.gilvum_PYR-GCK RYSRRLRRVMYMSALTAIRCDPDSKAYYQRKRDEGK------RPIPATIC
MSMEG_4550|M.smegmatis_MC2_155 RYSRRLRRVMYMSALTAIRCDPDSKAYYQRKRDEGK------RPIPATIC
Rv2177c|M.tuberculosis_H37Rv TGNQHLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRSPAANKKAIIA
Mb2447c|M.bovis_AF2122/97 TGNQHLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRSPAANKKAIIA
Mvan_4882|M.vanbaalenii_PYR-1 HGNRYLAQILGEAAIAASRTDTFLGQRYRRIARRRG-------NKRALVA
MAV_0496|M.avium_104 IKNRRLAAVGPIWALGSLRASPGARRHYDARRAAGD------WNHQAQRH
.: * * : : . * *
MMAR_3782|M.marinum_M LARRRINVIWAMLRD-------------HTHYHEPDLVNTPLAA------
TH_3017|M.thermoresistible__bu LARRRLNVLWAMLRD-------------HTTYQPTTPTAAAAA-------
Mflv_4200|M.gilvum_PYR-GCK LARRRTNVLYALIRD-------------NRTWQPDSPPVTAAA-------
MSMEG_4550|M.smegmatis_MC2_155 LARRRTNVLYALIRD-------------NRTWQPESPPNIAAA-------
Rv2177c|M.tuberculosis_H37Rv VAHKLIVIIWHVLAT-GRPYQDLGADYFTTRMDPDKERRRLVAKLEAQGL
Mb2447c|M.bovis_AF2122/97 VAHKLIVIIWHVLAT-GRPYQDLGADYFTTRMDPDKERRRLVAKLEAQGL
Mvan_4882|M.vanbaalenii_PYR-1 VGRSILVIIWHLLTDPDATFIDLGPDHYTKHLNPETKRRNHIRQLEALGY
MAV_0496|M.avium_104 LFNKFLGQLHHCLQTGRLYNEHLAFPLNRPGFDGGSCYWISTSGWSVRFV
: . : : .
MMAR_3782|M.marinum_M --------
TH_3017|M.thermoresistible__bu --------
Mflv_4200|M.gilvum_PYR-GCK --------
MSMEG_4550|M.smegmatis_MC2_155 --------
Rv2177c|M.tuberculosis_H37Rv GVTLEPAA
Mb2447c|M.bovis_AF2122/97 GVTLEPAA
Mvan_4882|M.vanbaalenii_PYR-1 TVTLTPAA
MAV_0496|M.avium_104 A-------