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M. bovis AF2122 / 97 Mb2447c (-)

annotation: transposase
coordinates: 2688961 - 2689653
length: 230

VLADLARGSMRSKIPDLQRALEGRFDDHHALMCRLHLAHLDQLDAMIGALDEQIEQLMHPFCARRELIAS
IPGIGVGASATVISEIGADPAAWFPSAEHLASWVRLCPGNHESAGKRHHGARRTGNQHLQPVLVECAWAA
VRTDGYLREYYRRQVRKFGGFRSPAANKKAIIAVAHKLIVIIWHVLATGRPYQDLGADYFTTRMDPDKER
RRLVAKLEAQGLGVTLEPAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2447c--100% (230)transposase
M. bovis AF2122 / 97Mb2199c-e-12899.55% (221) transposase
M. bovis AF2122 / 97Mb2037-7e-0926.89% (212) transposase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4200-2e-0730.97% (155) transposase IS116/IS110/IS902 family protein
M. tuberculosis H37RvRv2424c-1e-13298.70% (230) transposase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_3782-6e-0626.26% (198) transposase
M. avium 104MAV_0496-4e-0529.56% (159) transposase IS116/IS110/IS902
M. smegmatis MC2 155MSMEG_4550-4e-0730.32% (155) transposase
M. thermoresistible (build 8)TH_3017-1e-0830.26% (152) PUTATIVE transposase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4882-2e-4543.97% (232) transposase IS116/IS110/IS902 family protein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3782|M.marinum_M               ----------MPTVWAGVDTGKRTHHCVVLDRNGGVLLSRPVDNDETALL
TH_3017|M.thermoresistible__bu      ---------------------------VVIDAQGKRLLSQRVANDEATLL
Mflv_4200|M.gilvum_PYR-GCK          --------MTTGQVWAGVDVGKEHHWVCAVDDSGKVVLSRRLVNDEQPIR
MSMEG_4550|M.smegmatis_MC2_155      --------MAAGQVWAGVDVGKEHHWVCVVDDSGKVVLSRRLVNDEQPIR
Mb2447c|M.bovis_AF2122/97           --------------------------------------------------
Rv2424c|M.tuberculosis_H37Rv        --------------------------------------------------
Mvan_4882|M.vanbaalenii_PYR-1       MLVESEDSEQIIARVAALDIGKAELVCCVRVPGRGTRRLQEVSTHSTMAR
MAV_0496|M.avium_104                -----------------------------------MVARGRVSNDAAGFA
                                                                                      

MMAR_3782|M.marinum_M               ELIEAVVGVAAGREVCWATDLNAGGAAMLITLLAAHDQQLLYIPGRIVHH
TH_3017|M.thermoresistible__bu      KLISTVATMADGGEVTWAIDLNAGGAALLITLLIAADQRLLYIPGRTVHH
Mflv_4200|M.gilvum_PYR-GCK          ELVAEIDELAER--VSWTVDLTTVYAALVLTVLADAGKTVRYLAGRAVWQ
MSMEG_4550|M.smegmatis_MC2_155      ELVAEIDELAER--VLWAVDLTTVYAALLLTVLADAGKTVRYLAGRAVWQ
Mb2447c|M.bovis_AF2122/97           --------------------------------------------------
Rv2424c|M.tuberculosis_H37Rv        ------------------------------------------MQCRAREE
Mvan_4882|M.vanbaalenii_PYR-1       SLTELANHLVESGVQRVVMEATSDYWKPVFYLLEAHGLDPWLVNARDVKH
MAV_0496|M.avium_104                ALLTLLAEAGDSAAHPIPVGIETDRG-LWVAALRETGRVIYPINPLAASR
                                                                                      

MMAR_3782|M.marinum_M               AAATYRG-DGKTDAKNARIIADQARMR-TDLQPVRRADPIATDLRLLTSR
TH_3017|M.thermoresistible__bu      ASGSYRG-EGKTDAKDAAVIADQARMR-RDLQPLRPGDDITVELRILTSR
Mflv_4200|M.gilvum_PYR-GCK          ASATYRGGEAKTDAKDARVIADQARMRGQDLPVLHPDDDLISELRMLTGH
MSMEG_4550|M.smegmatis_MC2_155      ASATYRGGEAKTDAKDARVIADQSRMRGQDLPVLHPNDDLISELRMLTGH
Mb2447c|M.bovis_AF2122/97           --------------------------------------------------
Rv2424c|M.tuberculosis_H37Rv        R-----PGR-KTDLLDAEWLVHLLECG--LLRGWLIPPADIKAARDVIRY
Mvan_4882|M.vanbaalenii_PYR-1       L-----PGRPKTDVLDAVWLAKLAERQ--MLRPSFVPPPPIRQLRDLTRY
MAV_0496|M.avium_104                YRARHAVSGAKSDATDAVLLANIVRTDAAAHRPLPADTELAQAIRVLARA
                                                                                      

MMAR_3782|M.marinum_M               RTDVVCDRVRAINRLRQTLLEYFPPLERAFD-----YSKSKAALTLLSRY
TH_3017|M.thermoresistible__bu      RTDLVADRTRTINRLRAQLLEYFPALERAFD-----YSTSKAALLLLTGY
Mflv_4200|M.gilvum_PYR-GCK          RADLVADRTRTINRLRQQLVAVCPALERAAQ-----PSQDRGWVILLARY
MSMEG_4550|M.smegmatis_MC2_155      RADLVADRTRTINRLRQQLVAVCPALERAAQ-----LSQDRGWVVLLARY
Mb2447c|M.bovis_AF2122/97           --------------------------------------------------
Rv2424c|M.tuberculosis_H37Rv        RRKLVEHRTSKLQRLGNVLQDAGIKADSVAS-----SVTPKSVRAMVEAL
Mvan_4882|M.vanbaalenii_PYR-1       RIDLVATRTAERNRVEKLLEDACIKLSVVAS-----DIFGVSGRAMMAAL
MAV_0496|M.avium_104                QQDAVWARQQIGNQIRDLLKDFYPAAIAAFAGLPEGGLARADARTILAAA
                                                                                      

MMAR_3782|M.marinum_M               QTPDSLRRIGPTRLATWLKARGCRNSATVAQTAVQAAQTQHTTLPTQTVG
TH_3017|M.thermoresistible__bu      QTPDGLRRAGAARLAVWLGKRKARNADAVAAKALQAAHAQHTVIPGQQLA
Mflv_4200|M.gilvum_PYR-GCK          QRPKAIRQSGVSRLTKVLTDAGVRNAASIAAAAVAAVKTQTMRLPGEEVA
MSMEG_4550|M.smegmatis_MC2_155      QRPKAIRQSGVSRLTKVLTDAGVRNAASIAGAAVAAVKTQTVRLPGEEVA
Mb2447c|M.bovis_AF2122/97           -------------MLADLARGSMRSKIPDLQRALEGRFDDHHAL------
Rv2424c|M.tuberculosis_H37Rv        -----IDGERRPAVLADLARGSMRSKIPDLQRALEGRFDDHHAL------
Mvan_4882|M.vanbaalenii_PYR-1       -----IAGERDPKVLAQLARSRMRTKIGRLEEAFNGHFNAHHGF------
MAV_0496|M.avium_104                PTPTQAATLTPARLRRLLTKAGRRRHLDRDIERLRAVFTDTYLHQPPAVE
                                                 :   *     *         . .              

MMAR_3782|M.marinum_M               AQLVPRLAAEITTIDAELAHVDNEITARFA---DHDSAEILTSMPGFGPV
TH_3017|M.thermoresistible__bu      AAMVARLAKEVMALDTEIGDTDAMIEERFH---RHRHAEIIVSMSGFGVT
Mflv_4200|M.gilvum_PYR-GCK          AGLIADLAREVIALDDRIKTTDADIEGRFR---RHPLAEVITSMPGIGFR
MSMEG_4550|M.smegmatis_MC2_155      AGLVADLAREVIALDDRIKTTDADIEGRFR---RHPLAEVITSMPGMGFR
Mb2447c|M.bovis_AF2122/97           --MCRLHLAHLDQLDAMIGALDEQIEQLMHP--FCARRELIASIPGIGVG
Rv2424c|M.tuberculosis_H37Rv        --MCRLHLAHLDQLDAMIGALDEQIEQLMHP--FCARRELIASIPGIGVG
Mvan_4882|M.vanbaalenii_PYR-1       --LLTRMLARLDGIDADIAVLDEQIEVYLAP--FAAAAARLDEIPGIGAV
MAV_0496|M.avium_104                NAMGIQLAALLRQLEAACTAADELAEAAIAHFEQHPDAKIITSFPGLGML
                                      :       :  ::      *      :           : .:.*:*  

MMAR_3782|M.marinum_M               LAATFLAQIGGNLDGFD-TVDRLACVAGLAPVPRDSGRISGNLHRPRRFN
TH_3017|M.thermoresistible__bu      LGAEFLAATGGDMSAFD-SVDRLAGVAGLAPVPRDSGRISGNLQRPRRYN
Mflv_4200|M.gilvum_PYR-GCK          LGAEFLAAVG-DPALIG-SADQLAAWAGLAPVSRDSGKRTGRLHTPKRYS
MSMEG_4550|M.smegmatis_MC2_155      LGAELLAAVG-DPALIG-SADQLAAWAGLAPVSRDSRKRTGRLHTPKRYS
Mb2447c|M.bovis_AF2122/97           ASATVISEIGADPAAWFPSAEHLASWVRLCPGNHESAGKRHHGARR-TGN
Rv2424c|M.tuberculosis_H37Rv        ASATVISEIGADPAAWFPSAEHLASWVRLCPGNHESAGKRHHGARR-TGN
Mvan_4882|M.vanbaalenii_PYR-1       AAAIILAEIGTD-MSVFPTAGHLCSWAKFSPGIQSSAGKTKGTASTGHGN
MAV_0496|M.avium_104                AGARVLAEIGDDRTRFA-DARGLKAFAGSAPITRASGKKTVVLHRH-IKN
                                     .* .::  * :       .  *   .  .*  : *             .

MMAR_3782|M.marinum_M               RRLLRPCYLAALSSLKNSPASRTFYDRKRAEGK------SHKQALIALAR
TH_3017|M.thermoresistible__bu      RRLLRVCYLSALSSIRSDPASRTYYNRKRAEGK------RHSQAVLALAR
Mflv_4200|M.gilvum_PYR-GCK          RRLRRVMYMSALTAIRCDPDSKAYYQRKRDEGK------RPIPATICLAR
MSMEG_4550|M.smegmatis_MC2_155      RRLRRVMYMSALTAIRCDPDSKAYYQRKRDEGK------RPIPATICLAR
Mb2447c|M.bovis_AF2122/97           QHLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRSPAANKKAIIAVAH
Rv2424c|M.tuberculosis_H37Rv        QHLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRSPAANKKAITTVAH
Mvan_4882|M.vanbaalenii_PYR-1       RYLAQILGEAAIAASRTDTFLGQRYRRIARRRG-------NKRALVAVGR
MAV_0496|M.avium_104                RRLAAVGPIWALGSLRASPGARRHYDARRAAGD------WNHQAQRHLFN
                                    : *       *  : : .      *                  *   : .

MMAR_3782|M.marinum_M               RRINVIWAMLRD-------------HTHYHEPDLVNTPLAA---------
TH_3017|M.thermoresistible__bu      RRLNVLWAMLRD-------------HTTYQPTTPTAAAAA----------
Mflv_4200|M.gilvum_PYR-GCK          RRTNVLYALIRD-------------NRTWQPDSPPVTAAA----------
MSMEG_4550|M.smegmatis_MC2_155      RRTNVLYALIRD-------------NRTWQPESPPNIAAA----------
Mb2447c|M.bovis_AF2122/97           KLIVIIWHVLAT-GRPYQDLGADYFTTRMDPDKERRRLVAKLEAQGLGVT
Rv2424c|M.tuberculosis_H37Rv        KLIVIIWHVLAT-GRPHQDLGADYFTTRMDPDKERRRLVAKLEAQGLGVT
Mvan_4882|M.vanbaalenii_PYR-1       SILVIIWHLLTDPDATFIDLGPDHYTKHLNPETKRRNHIRQLEALGYTVT
MAV_0496|M.avium_104                KFLGQLHHCLQTGRLYNEHLAFPLNRPGFDGGSCYWISTSGWSVRFVA--
                                         :   :                   .                    

MMAR_3782|M.marinum_M               -----
TH_3017|M.thermoresistible__bu      -----
Mflv_4200|M.gilvum_PYR-GCK          -----
MSMEG_4550|M.smegmatis_MC2_155      -----
Mb2447c|M.bovis_AF2122/97           LEPAA
Rv2424c|M.tuberculosis_H37Rv        LEPAA
Mvan_4882|M.vanbaalenii_PYR-1       LTPAA
MAV_0496|M.avium_104                -----