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M. tuberculosis H37Rv Rv2014 (-)

annotation: POSSIBLE TRANSPOSASE
coordinates: 2261098 - 2261688
length: 196

VLHDRLTGAPRGATGDEGAANAHITRAMVAALTSVATQIKTLDAQIAEQLSLHADAHIFTSLPRSGTVRA
ARLLAEIGDCRARFPTPESLACLAGVAPSTRQSGKVKHVGFRWAADKQLRDAVCDFAGDSRRANLWAADR
YNRAIARGHDHPHAVRILARAWLYAIWHCWQDGAAYHPANHRALQALLNQDQDRAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2014--100% (196)POSSIBLE TRANSPOSASE
M. tuberculosis H37RvRv2177c-9e-0925.12% (203) transposase
M. tuberculosis H37RvRv2424c-1e-0826.42% (212) transposase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2037-1e-113100.00% (196) transposase
M. gilvum PYR-GCKMflv_1197-1e-1532.78% (180) transposase, IS111A/IS1328/IS1533
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_3782-1e-1432.48% (157) transposase
M. avium 104MAV_0496-2e-1435.10% (151) transposase IS116/IS110/IS902
M. smegmatis MC2 155MSMEG_1732-1e-1431.76% (170) transposase IS116/IS110/IS902
M. thermoresistible (build 8)TH_3366-8e-4750.00% (184) PUTATIVE transferase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4491-2e-1431.21% (173) transposase, IS111A/IS1328/IS1533

CLUSTAL 2.0.9 multiple sequence alignment


Rv2014|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2037|M.bovis_AF2122/97            --------------------------------------------------
TH_3366|M.thermoresistible__bu      ----------------------VGKILAQFMIDHTADGIATLIRKLSKFG
Mflv_1197|M.gilvum_PYR-GCK          -MTLFIGDDWAEDHHDIHLMDAEGTRLASRRLPEGLAGIRGFHELVAAHA
Mvan_4491|M.vanbaalenii_PYR-1       --MIFVGDDWAEDHHDVYLMDESGQRLAARRLPEGLSGIRALHELIAGYA
MSMEG_1732|M.smegmatis_MC2_155      ---------------------------------------------MAAHC
MAV_0496|M.avium_104                -------------------------MVARGRVSNDAAGFAALLTLLAEAG
MMAR_3782|M.marinum_M               MPTVWAGVDTGKRTHHCVVLDRNGGVLLSRPVDNDETALLELIEAVVGVA
                                                                                      

Rv2014|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2037|M.bovis_AF2122/97            --------------------------------------------------
TH_3366|M.thermoresistible__bu      DPADV--HIGIERPNGRLVDLLLEAGHPVIPVSPNAIKTWRDGEVISGAK
Mflv_1197|M.gilvum_PYR-GCK          QDPTE-VVIGIETDRGLWVEALAAAGYEVFAVNPLAVARYRDRHQVSGAK
Mvan_4491|M.vanbaalenii_PYR-1       EEPDQ-VIVGIETDRGLWVSALAAAGYRVWAINPMAAARYRDRHHVSGAK
MSMEG_1732|M.smegmatis_MC2_155      EDSEQ-VVVGIETDNGLWVQALHAVGYRVYGINPLSASRYRDRHCVSGAK
MAV_0496|M.avium_104                DSAAHPIPVGIETDRGLWVAALRETGRVIYPINPLAASRYRARHAVSGAK
MMAR_3782|M.marinum_M               AGREVCWATDLNAGGAAMLITLLAAHDQQLLYIPGRIVHHAAATYRGDGK
                                                                                      

Rv2014|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2037|M.bovis_AF2122/97            --------------------------------------------------
TH_3366|M.thermoresistible__bu      SDAGDALVIAEYLRLRHHRLRPAAPYSSSTKALRTVVRTRDDVVAMRVAA
Mflv_1197|M.gilvum_PYR-GCK          SDAADAKLLADLVRTDRHNHRPIAGDTPEVEAIKVLARAHQNLIWSRNRN
Mvan_4491|M.vanbaalenii_PYR-1       SDASDAKLLADLVRTDRHNHREIAGDRPQAEAIKVLARSHQSLIWARTRH
MSMEG_1732|M.smegmatis_MC2_155      SDAGDAKILADLVRTDRHNHRQLADDSSAVHAIKVLARTHQSLVWARTRH
MAV_0496|M.avium_104                SDATDAVLLANIVRTDAAAHRPLPADTELAQAIRVLARAQQDAVWARQQI
MMAR_3782|M.marinum_M               TDAKNARIIADQARMR-TDLQPVRRADPIATDLRLLTSRRTDVVCDRVRA
                                                                                      

Rv2014|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2037|M.bovis_AF2122/97            --------------------------------------------------
TH_3366|M.thermoresistible__bu      TNQLSALLDDHWPGAKAIFADVES-----PISLAFLRRYPTAASAARLGE
Mflv_1197|M.gilvum_PYR-GCK          TNALRSALREYYPAALEAFASLSD-----RDALAILGRAPTPTDAARLSV
Mvan_4491|M.vanbaalenii_PYR-1       ANMLRSGLREYYPAALEAFDSLTD-----SDALAILGRAPTPDQGARLSL
MSMEG_1732|M.smegmatis_MC2_155      SNALRAGLSQYYPAALAAFPDIDG-----RDALAVLQRAPDPSAGATLSL
MAV_0496|M.avium_104                GNQIRDLLKDFYPAAIAAFAGLPEGGLARADARTILAAAPTPTQAATLTP
MMAR_3782|M.marinum_M               INRLRQTLLEYFPPLERAFDYSKS-----KAALTLLSRYQTPDSLRRIGP
                                                                                      

Rv2014|M.tuberculosis_H37Rv         -------------------MLHDRLTGAPRG---ATG-DEGAANAHITRA
Mb2037|M.bovis_AF2122/97            -------------------MLHDRLTGAPRG---ATG-DEGAANAHITRA
TH_3366|M.thermoresistible__bu      KRLAAFLVKHSYSGRRPVKELLTRLRSAPAG---TTDPVLTIAVRDVVLA
Mflv_1197|M.gilvum_PYR-GCK          SKIRSALKAAG--RQRNLDAKALEIQTALRSDQLAAAPAVTAAFGATTRA
Mvan_4491|M.vanbaalenii_PYR-1       AKIGSALKSAG--RQRNIESRAAEIQTALRGEHLTAPPAVAAAFGATTAA
MSMEG_1732|M.smegmatis_MC2_155      SKISSALKVAG--RQRSIDARAREIQTALRSPQLHTSDQVVAALSASTTA
MAV_0496|M.avium_104                ARLRRLLTKAG--RRRHLDRDIERLRAVFTDTYLHQPPAVENAMGIQLAA
MMAR_3782|M.marinum_M               TRLATWLKARG-----CRNSATVAQTAVQAAQTQHTTLPTQTVGAQLVPR
                                                               .              .       

Rv2014|M.tuberculosis_H37Rv         MVAALTSVATQIKTLDAQIAEQLSLHADAHIFTSLPRSGTVRAARLLAEI
Mb2037|M.bovis_AF2122/97            MVAALTSVATQIKTLDAQIAEQLSLHADAHIFTSLPRSGTVRAARLLAEI
TH_3366|M.thermoresistible__bu      LVSVIEALNSAGKALDRSVIARLGEHPDAEVFTSLPRSGQINAAQVLAEW
Mflv_1197|M.gilvum_PYR-GCK          AVAIITELNHHIADLEAELAAHFETHPDADIYLSLPGLGVILGARVLGEF
Mvan_4491|M.vanbaalenii_PYR-1       AVHVITALNDQIAELETALADHFEAHPDADIYRSLPGLGVILGARVLGEF
MSMEG_1732|M.smegmatis_MC2_155      TVAVLLVLNTQISELQTQLTDHFETHPDADIYLSLPGLGVILGARVLGEF
MAV_0496|M.avium_104                LLRQLEAACTAADELAEAAIAHFEQHPDAKIITSFPGLGMLAGARVLAEI
MMAR_3782|M.marinum_M               LAAEITTIDAELAHVDNEITARFADHDSAEILTSMPGFGPVLAATFLAQI
                                        :         :      ::  * .*.:  *:*  * : .* .*.: 

Rv2014|M.tuberculosis_H37Rv         GDCRARFPTPESLACLAGVAPSTRQSGKVKHVGFR-WAADKQLRDAVCDF
Mb2037|M.bovis_AF2122/97            GDCRARFPTPESLACLAGVAPSTRQSGKVKHVGFR-WAADKQLRDAVCDF
TH_3366|M.thermoresistible__bu      GDSRAAYDGPDAVAALAGVTPVTKSSGKQHAVHFR-WACNKRFRRALTTF
Mflv_1197|M.gilvum_PYR-GCK          GDDPNRYTTAKSRKNYAGTSPLTIASGKKRAVLAR-HVRNRRLYDAIDQW
Mvan_4491|M.vanbaalenii_PYR-1       GDDPNRYTTAKCRKNYAGTSPLTIASGRKRAVLAR-HVRNKRLYDALDQW
MSMEG_1732|M.smegmatis_MC2_155      GDDPNRYTDAKSRKNYAATSQITVASGRRRAVIAR-HIKNRHLADAIDMW
MAV_0496|M.avium_104                GDDRTRFADARGLKAFAGSAPITRASGKKTVVLHR-HIKNRRLAAVGPIW
MMAR_3782|M.marinum_M               GGNLDGFDTVDRLACVAGLAPVPRDSGRISGNLHRPRRFNRRLLRPCYLA
                                    *.    :         *. :  .  **:      *    ::::       

Rv2014|M.tuberculosis_H37Rv         AGDSRRANLWAADRYNRAIARGHDHPHAVRILARAWLYAIWHCWQDGAAY
Mb2037|M.bovis_AF2122/97            AGDSRRANLWAADRYNRAIARGHDHPHAVRILARAWLYAIWHCWQDGAAY
TH_3366|M.thermoresistible__bu      ADNSRHQSTWAADIYNRARARGHDHPHAVRILARAWIRVIYRCWHDQSPY
Mflv_1197|M.gilvum_PYR-GCK          AFCALTNSPGARTFYDQHRAAGDLHHQALRALGNRLVGILHGCLRHHTPY
Mvan_4491|M.vanbaalenii_PYR-1       AFCTLTRSPGARAYYDQHRAAGDTHHQALRALANRLVGILHGCLRHHSPY
MSMEG_1732|M.smegmatis_MC2_155      AYSSLRASPGARTFYDQHRAAGDTHHQALRALGNRFIGILHGCLRHHTHY
MAV_0496|M.avium_104                ALGSLRASPGARRHYDARRAAGDWNHQAQRHLFNKFLGQLHHCLQTGRLY
MMAR_3782|M.marinum_M               ALSSLKNSPASRTFYDRKRAEGKSHKQALIALARRRINVIWAMLRDHTHY
                                    *  :   .  :   *:   * *. : :*   * .  :  :    :    *

Rv2014|M.tuberculosis_H37Rv         HPANHRAL-----------QALLNQDQDRAA------
Mb2037|M.bovis_AF2122/97            HPANHRAL-----------QALLNQDQDRAA------
TH_3366|M.thermoresistible__bu      DPARHGAV-----------QKLHTAA-----------
Mflv_1197|M.gilvum_PYR-GCK          SEHKAWAH-----------RQTDSRAA----------
Mvan_4491|M.vanbaalenii_PYR-1       DEHKAWAH-----------RKPAAA------------
MSMEG_1732|M.smegmatis_MC2_155      NEHTAWARGIVNTCGSGCFRRPPFRRADRRLRAMLAG
MAV_0496|M.avium_104                NEHLAFPLNRPGFDGGSCYWISTSGWSVRFVA-----
MMAR_3782|M.marinum_M               HEPDLVNT-------------PLAA------------