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VVARGRVSNDAAGFAALLTLLAEAGDSAAHPIPVGIETDRGLWVAALRETGRVIYPINPLAASRYRARHA VSGAKSDATDAVLLANIVRTDAAAHRPLPADTELAQAIRVLARAQQDAVWARQQIGNQIRDLLKDFYPAA IAAFAGLPEGGLARADARTILAAAPTPTQAATLTPARLRRLLTKAGRRRHLDRDIERLRAVFTDTYLHQP PAVENAMGIQLAALLRQLEAACTAADELAEAAIAHFEQHPDAKIITSFPGLGMLAGARVLAEIGDDRTRF ADARGLKAFAGSAPITRASGKKTVVLHRHIKNRRLAAVGPIWALGSLRASPGARRHYDARRAAGDWNHQA QRHLFNKFLGQLHHCLQTGRLYNEHLAFPLNRPGFDGGSCYWISTSGWSVRFVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0496 | - | - | 100% (404) | transposase IS116/IS110/IS902 |
| M. avium 104 | MAV_1872 | - | 7e-10 | 96.00% (25) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2036 | - | 2e-15 | 34.93% (146) | transposase |
| M. gilvum PYR-GCK | Mflv_1197 | - | 5e-85 | 45.62% (377) | transposase, IS111A/IS1328/IS1533 |
| M. tuberculosis H37Rv | Rv2014 | - | 5e-14 | 35.10% (151) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4323 | - | 3e-73 | 60.16% (246) | transposase |
| M. smegmatis MC2 155 | MSMEG_4081 | - | 3e-86 | 46.07% (382) | transposase IS116/IS110/IS902 |
| M. thermoresistible (build 8) | TH_2233 | - | 3e-84 | 45.62% (377) | Transposase IS116/IS110/IS902 family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4491 | - | 7e-86 | 45.55% (382) | transposase, IS111A/IS1328/IS1533 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0496|M.avium_104 ---------------------------------MVARGRVSNDAAGFAAL
MMAR_4323|M.marinum_M MPEIRSYDSAHLYCGIVWGAEVHDVGAVDDVGRIVLRKRVQSDPAGLTHL
Mb2036|M.bovis_AF2122/97 ------------------------MSIVDARGREVRRATIEHNAAGLREL
Mflv_1197|M.gilvum_PYR-GCK ---------MTLFIGDDWAEDHHDIHLMDAEGTRLASRRLPEGLAGIRGF
TH_2233|M.thermoresistible__bu ---------------------------MDAEGAKLASRRLPEGLAGIGGF
MSMEG_4081|M.smegmatis_MC2_155 ----------MLFVGDDWAEDHHDLYLMNEAGDRLASRRLPEGLAGIRLL
Mvan_4491|M.vanbaalenii_PYR-1 ----------MIFVGDDWAEDHHDVYLMDESGQRLAARRLPEGLSGIRAL
Rv2014|M.tuberculosis_H37Rv ----------------------------------MLHDRLTGAPRGATGD
: : *
MAV_0496|M.avium_104 LTLLAEAGDSAAHPIPVGIETDRGLWVAALRETGRVIYPINPLAASRYRA
MMAR_4323|M.marinum_M LTLLARAGDSPHHPIPLAAEVDRRLWVRALRSAGRPIYSIDALASARYHT
Mb2036|M.bovis_AF2122/97 LELLSRAGAR-----EVAIERPDGPVVDTLLEAGITVVVISPNQLKNLRG
Mflv_1197|M.gilvum_PYR-GCK HELVAAHAQDPTE-VVIGIETDRGLWVEALAAAGYEVFAVNPLAVARYRD
TH_2233|M.thermoresistible__bu HDLVAAHAEEPAQ-VVIGIETDRGLWVEALAAAGYQVFAINPLAVARYRD
MSMEG_4081|M.smegmatis_MC2_155 HDLIAAHADDPAQ-VAVGIETDRGLWVEALTGAGYQVYAVNPLAVARYRD
Mvan_4491|M.vanbaalenii_PYR-1 HELIAGYAEEPDQ-VIVGIETDRGLWVSALAAAGYRVWAINPMAAARYRD
Rv2014|M.tuberculosis_H37Rv EGAANAHITRAMVAALTSVATQIKTLDAQIAEQ------LSLHADAHIFT
. : :. .
MAV_0496|M.avium_104 RHAVSGAKSDATDAVLLANIVRTDAAAHRPLPADTELAQAIRVLARAQQD
MMAR_4323|M.marinum_M SHAVSAAKSANSGPVLLANIVRTNQAALRPLPPYTGPPDALGALARDLQN
Mb2036|M.bovis_AF2122/97 RYGSAGNKDDRFDAFVLADTLRTDRSRLRPLLPDTPATATLRRTCRPRKD
Mflv_1197|M.gilvum_PYR-GCK RHQVSGAKSDAADAKLLADLVRTDRHNHRPIAGDTPEVEAIKVLARAHQN
TH_2233|M.thermoresistible__bu RHQVSGAKSDAGDAKVLADLVRTDRHNHRPIAGDTPQVEAIKVLARAHQS
MSMEG_4081|M.smegmatis_MC2_155 RHAVSGAKSDAADAKLLADLVRTDRHNHRLIAGDTPDAEAVKVLARAHQN
Mvan_4491|M.vanbaalenii_PYR-1 RHHVSGAKSDASDAKLLADLVRTDRHNHREIAGDRPQAEAIKVLARSHQS
Rv2014|M.tuberculosis_H37Rv SLPRSG---TVRAARLLAEIGDCRARFPTPESLACLAGVAPSTRQSGKVK
:. . :**: : .
MAV_0496|M.avium_104 AVWARQQIGNQIRDLLKDFYPAAIAAFAGLPEGGLARADARTILAAAPTP
MMAR_4323|M.marinum_M AVWLRQQLENRIVDLLMDFYPAAIAAFADPLQGGLVRRDARMLLSVAPNP
Mb2036|M.bovis_AF2122/97 LVAHRVALANQLRAHLRVVFPGVVGLFADLDSP--ISLAFLTFLPRFDCQ
Mflv_1197|M.gilvum_PYR-GCK LIWSRNRNTNALRSALREYYPAALEAFASLSDR-----DALAILGRAPTP
TH_2233|M.thermoresistible__bu LIWARTRHTNTLRSALREYYPAALEAFDDLADR-----DALAILGRAPTP
MSMEG_4081|M.smegmatis_MC2_155 LIWTRNRHTNALRSALREYYPAALEAFDDLSDR-----DALAILGHAPDP
Mvan_4491|M.vanbaalenii_PYR-1 LIWARTRHANMLRSGLREYYPAALEAFDSLTDS-----DALAILGRAPTP
Rv2014|M.tuberculosis_H37Rv HVGFRWAADKQLRDAVCDFAGDSRRANLWAADR-----YNRAIARGHDHP
: * : : : . :
MAV_0496|M.avium_104 TQAATLTPARLRRLLTKAGRRRHLDRDIERLRAVFTDTYLHQPPAVENAM
MMAR_4323|M.marinum_M NRAAALTTSRLRQLLRNAGRQRHVDRDAERLRQVFTATYPQQPTHAETAM
Mb2036|M.bovis_AF2122/97 DRADWLSVKRLAGWLAAAGYCGRAPRPAHRCPARRHR-------------
Mflv_1197|M.gilvum_PYR-GCK TDAARLSVSKIRSALKAAGRQRNLDAKALEIQTALRSDQLAAAPAVTAAF
TH_2233|M.thermoresistible__bu TDATGLSLPKIRSALKTAGRQRNLDARALQIQTALRTEQLTAPASVTAAF
MSMEG_4081|M.smegmatis_MC2_155 RQASSLSLAKIRSALKAAGRQRNIDIRAQEIQAALRSEQLAAPAAVTAAF
Mvan_4491|M.vanbaalenii_PYR-1 DQGARLSLAKIGSALKSAGRQRNIESRAAEIQTALRGEHLTAPPAVAAAF
Rv2014|M.tuberculosis_H37Rv HAVRILARAWLYAIWHCWQDGAAYHPANHRALQALLNQDQDRAA------
*: : .
MAV_0496|M.avium_104 GIQLAALLRQLEAACTAADELAEAAIAHFEQHPDAKIITSFPGLGMLAGA
MMAR_4323|M.marinum_M GIRLAGQLAQLEAACITVDRLIEQATAQFG--------------------
Mb2036|M.bovis_AF2122/97 --------------------------------------------------
Mflv_1197|M.gilvum_PYR-GCK GATTRAAVAIITELNHHIADLEAELAAHFETHPDADIYLSLPGLGVILGA
TH_2233|M.thermoresistible__bu GATTRATVGIITELNRQIDNLDAELTSHFEMHPDADIYRSLPGLGVILGA
MSMEG_4081|M.smegmatis_MC2_155 AATTRATVGLVVELSRQIDDLENELAAHFETHPDADIYRSLPGLGVILGA
Mvan_4491|M.vanbaalenii_PYR-1 GATTAAAVHVITALNDQIAELETALADHFEAHPDADIYRSLPGLGVILGA
Rv2014|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0496|M.avium_104 RVLAEIGDDRTRFADARGLKAFAGSAPITRASGKKTVVLHRHIKNRRLAA
MMAR_4323|M.marinum_M --------------------------------------------------
Mb2036|M.bovis_AF2122/97 --------------------------------------------------
Mflv_1197|M.gilvum_PYR-GCK RVLGEFGDDPNRYTTAKSRKNYAGTSPLTIASGKKRAVLARHVRNRRLYD
TH_2233|M.thermoresistible__bu RVLGEFGDDPNRYTSAKSRKNYAGTSPLTIASGKKRAVLARHVRNRRLYD
MSMEG_4081|M.smegmatis_MC2_155 RVLGEFGDDPNRYTNAKCRKNYAGTSPLTIASGRKRAVLARHIRNRRLYD
Mvan_4491|M.vanbaalenii_PYR-1 RVLGEFGDDPNRYTTAKCRKNYAGTSPLTIASGRKRAVLARHVRNKRLYD
Rv2014|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0496|M.avium_104 VGPIWALGSLRASPGARRHYDARRAAGDWNHQAQRHLFNKFLGQLHHCLQ
MMAR_4323|M.marinum_M --------------------------------------------------
Mb2036|M.bovis_AF2122/97 --------------------------------------------------
Mflv_1197|M.gilvum_PYR-GCK AIDQWAFCALTNSPGARTFYDQHRAAGDLHHQALRALGNRLVGILHGCLR
TH_2233|M.thermoresistible__bu AIDQWAFCALTNSPGARAFYDQRRAADDLHHQALRALGNRLVGILHGCLR
MSMEG_4081|M.smegmatis_MC2_155 AIDQWAFCALTRSPGARQFYDHRRAEGDLHHQALRALGNRLVGILHGCLR
Mvan_4491|M.vanbaalenii_PYR-1 ALDQWAFCTLTRSPGARAYYDQHRAAGDTHHQALRALANRLVGILHGCLR
Rv2014|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0496|M.avium_104 TGRLYNEHLAFPLNRPGFDGGSCYWISTSGWSVRFVA
MMAR_4323|M.marinum_M -------------------------------------
Mb2036|M.bovis_AF2122/97 -------------------------------------
Mflv_1197|M.gilvum_PYR-GCK HHTPYSEHKAWAHRQT--DSRAA--------------
TH_2233|M.thermoresistible__bu HHTRYDEHTAWAHRQTTADTQAA--------------
MSMEG_4081|M.smegmatis_MC2_155 HRTRYDEHKAWAHRTP----AAA--------------
Mvan_4491|M.vanbaalenii_PYR-1 HHSPYDEHKAWAHRKP----AAA--------------
Rv2014|M.tuberculosis_H37Rv -------------------------------------