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PSADVGRQTRAQILRAAMDIASVKGLSGLSIGELAGRLGMSKSGLFRHFGAKEQLQLATVEAAVSVFEAE VVAPAMAAPPGVDRVRALMHAWVGYLERDVPAAAFSRPRPPTWTHSLARCATASPRPGGPESPPSRPTSK RRNAGARSGRISKCANSRSSCTPTRWRPTGRCCCSTTTAPESGRERRSTRPWPESAPPRRESNHEICQPY *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2160A | - | - | 100% (211) | hypothetical protein Rv2160A |
| M. tuberculosis H37Rv | Rv3208 | - | 1e-05 | 27.17% (92) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1019 | - | 3e-05 | 35.00% (60) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2184c | - | 1e-51 | 96.26% (107) | hypothetical protein Mb2184c |
| M. gilvum PYR-GCK | Mflv_4672 | - | 1e-07 | 30.43% (92) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-06 | 28.89% (90) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0901c | - | 2e-09 | 31.07% (103) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0389 | - | 1e-06 | 31.91% (94) | putative regulatory protein |
| M. avium 104 | MAV_5134 | - | 2e-07 | 33.33% (93) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1935 | - | 8e-07 | 29.35% (92) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0452 | - | 1e-06 | 29.35% (92) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_0905 | - | 2e-06 | 33.67% (98) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1795 | - | 5e-07 | 30.43% (92) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4672|M.gilvum_PYR-GCK --MSELAKTAPRRGGQPANG----TGSSGAARRGNRLPRDERRGQLLAAA
Mvan_1795|M.vanbaalenii_PYR-1 --MSEVARTAQRRGGQPANG----ASPSGAARRGNRMPRDERRGQLLIAA
MSMEG_1935|M.smegmatis_MC2_155 --MSDLANTAERRGEK---------RPAGGNRRGNRLPRDERRGQLLIAA
TH_0452|M.thermoresistible__bu --MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAA
MLBr_00815|M.leprae_Br4923 --MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVA
MMAR_0389|M.marinum_M --MSQAFGAIDTTDGD-----------------------TSTRQRILAAT
MAV_5134|M.avium_104 --MSHPVRATAIADTD-----------------------TSTRQRILAAT
Rv2160A|M.tuberculosis_H37Rv ------MPSADVG--------------------------RQTRAQILRAA
Mb2184c|M.bovis_AF2122/97 ------MPSADVG--------------------------RQTRAQILRAA
MUL_0905|M.ulcerans_Agy99 MTTGSAIRSRKTPTGR-----------------------EEVAAAVLEAA
MAB_0901c|M.abscessus_ATCC_199 --MTTPRTRPSRQVGRP----------------------GYDLDSLLAVA
:* .:
Mflv_4672|M.gilvum_PYR-GCK SEVFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKVELYLAVLQRHVDNL
Mvan_1795|M.vanbaalenii_PYR-1 SEVFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKVELYLAVLQRHVDNL
MSMEG_1935|M.smegmatis_MC2_155 SEVFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLQRHVDNL
TH_0452|M.thermoresistible__bu SEVFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNL
MLBr_00815|M.leprae_Br4923 SDVFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNL
MMAR_0389|M.marinum_M AEVLARSGKTKLSLSEVAAQAGVSRPTLYRWFASKEELLATFSRYERQVF
MAV_5134|M.avium_104 AEVLGRNGKTKLSLSDVATQAGVSRPTLYRWFASKEELLSAFSAYERQIF
Rv2160A|M.tuberculosis_H37Rv MDIASVKGLSGLSIGELAGRLGMSKSGLFRHFGAKEQLQLATVEAAVSVF
Mb2184c|M.bovis_AF2122/97 MDIASVKGLSGLSIGELAGRLGMSKSGLFRHFGAKEQLQLATVEAAVSVF
MUL_0905|M.ulcerans_Agy99 ADLFAERGPAATSIRDIAARSKVNHGLVFRHFGAKEQLVGAVLDYLGTHL
MAB_0901c|M.abscessus_ATCC_199 VSVFNQRGYDGTSMEHLSTRLGISKSSIYHHVSGKEELLRLAVDRALDAL
.: * .: .:: : :.: ::: . .* :* :
Mflv_4672|M.gilvum_PYR-GCK VSGVRQALRTTTDNRQRVRAAVQAFFDFIEHDSQGYRLIFEN--------
Mvan_1795|M.vanbaalenii_PYR-1 VSGVRQALRTTTDNRQRVRAAVQAFFDFIEHDGQGYRLIFEN--------
MSMEG_1935|M.smegmatis_MC2_155 VSGVRQALRTTTDNRQRLRAAVEAFFDFIEHDSQGYRLIFEN--------
TH_0452|M.thermoresistible__bu VSGVRQALRTTTDNRQRLRAAVQAFFDFIEHDGQGYRLIFEN--------
MLBr_00815|M.leprae_Br4923 VSSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFEN--------
MMAR_0389|M.marinum_M ESGLSKATAGLKG-----VDKLDAALRFIVDYQYSYSGVRMV--------
MAV_5134|M.avium_104 ESGLVKATAGLKG-----VDKLDAVLRFIVDYQHSYSGVRMV--------
Rv2160A|M.tuberculosis_H37Rv EAEVVAPAMAAPPGVDRVRALMHAWVGYLERDVPAAAFSRPRPPTWTHSL
Mb2184c|M.bovis_AF2122/97 EAEVVAPAMAAPPGVDRVRALMHAWVGYLERDVFPGGCFFAAAAADVDSQ
MUL_0905|M.ulcerans_Agy99 TELLRAGTP------------ADDLERALDRQMRVWARTLLD--------
MAB_0901c|M.abscessus_ATCC_199 FAATEAPDTTTGPAIDRLENLVKRSIQVLVQELPYVTLLLRIR-------
. :
Mflv_4672|M.gilvum_PYR-GCK ----DYVTEPQVAAQVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLV
Mvan_1795|M.vanbaalenii_PYR-1 ----DYVTEPQVAAQVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLV
MSMEG_1935|M.smegmatis_MC2_155 ----DYVTEPQVAAQVKVATEACTDAVFDLISRDSGLEAHRARMIAVGLV
TH_0452|M.thermoresistible__bu ----DYVTEPQVAAQVKVATEACTDAVFDLISQDSGLEAHRARMIAVGLV
MLBr_00815|M.leprae_Br4923 ----DNITEPRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLV
MMAR_0389|M.marinum_M ----DIEPELVISQMSGVIPEMREGLQRLLPGPNAAVKAATAIRIAISHY
MAV_5134|M.avium_104 ----DVEPEHTIAQFSWVIPQMREGLQRHLPGPNAAVKAATVIRIAISHY
Rv2160A|M.tuberculosis_H37Rv ARCATASPRPGGPESPPSRPTSKRRNAGARSGRISKCANSRSSCTPTRWR
Mb2184c|M.bovis_AF2122/97 P--GPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEARQLAFELHAY
MUL_0905|M.ulcerans_Agy99 ----GYPAEQLQTRFPNVAELLGQVRVHHGDDTTARLAVANAIALCLGWR
MAB_0901c|M.abscessus_ATCC_199 ----GNTAAERRALARRREFDDIVGNLVEEACNEGSIRAGVDPALTSRLI
.
Mflv_4672|M.gilvum_PYR-GCK SIS-VDSARYWLNNERPIDKDDAVEGTVQFIWGGLSHVPLTRS-
Mvan_1795|M.vanbaalenii_PYR-1 SIS-VDSARYWLNNDRPIDKDDAVEGTVQFIWGGLSHVPMTRS-
MSMEG_1935|M.smegmatis_MC2_155 AIS-VDSARYWLNNDRPIDKDSAVEGTVQFAWGGLSHVPLTRS-
TH_0452|M.thermoresistible__bu AIS-VDCARYWLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS-
MLBr_00815|M.leprae_Br4923 GIS-VDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-
MMAR_0389|M.marinum_M IVR-SDDADQFLAQLR---HAVGLKGG-----------------
MAV_5134|M.avium_104 IVR-SDDADQFLAQLR---HAVGIKAPTD---------------
Rv2160A|M.tuberculosis_H37Rv PTG-RCCCSTTTAPESGRERRSTRPWPESAPPRRESNHEICQPY
Mb2184c|M.bovis_AF2122/97 AME-ANWALLLLDDDGAGER--ARTAIDAALARVGTTQEGVES-
MUL_0905|M.ulcerans_Agy99 LFEPMLRSATGLDELADADLRQAVTDEVARIIEPSGRG------
MAB_0901c|M.abscessus_ATCC_199 FGT-VNSLIEWYRPSRTLSADEVADAVATMIFDGLRTRSGQH--