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VAAHCEDSEQVVVGIETDNGLWVQALHAVGYRVYGINPLSASRYRDRHCVSGAKSDAGDAKILADLVRTD RHNHRQLADDSSAVHAIKVLARTHQSLVWARTRHSNALRAGLSQYYPAALAAFPDIDGRDALAVLQRAPD PSAGATLSLSKISSALKVAGRQRSIDARAREIQTALRSPQLHTSDQVVAALSASTTATVAVLLVLNTQIS ELQTQLTDHFETHPDADIYLSLPGLGVILGARVLGEFGDDPNRYTDAKSRKNYAATSQITVASGRRRAVI ARHIKNRHLADAIDMWAYSSLRASPGARTFYDQHRAAGDTHHQALRALGNRFIGILHGCLRHHTHYNEHT AWARGIVNTCGSGCFRRPPFRRADRRLRAMLAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1732 | - | - | 100% (383) | transposase IS116/IS110/IS902 |
| M. smegmatis MC2 155 | MSMEG_4081 | - | e-141 | 67.99% (353) | transposase IS116/IS110/IS902 |
| M. smegmatis MC2 155 | MSMEG_3341 | - | e-141 | 67.99% (353) | transposase IS116/IS110/IS902 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2037 | - | 2e-14 | 31.76% (170) | transposase |
| M. gilvum PYR-GCK | Mflv_1197 | - | 1e-145 | 69.69% (353) | transposase, IS111A/IS1328/IS1533 |
| M. tuberculosis H37Rv | Rv2014 | - | 2e-14 | 31.76% (170) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3782 | - | 6e-29 | 30.43% (299) | transposase |
| M. avium 104 | MAV_0496 | - | 3e-83 | 46.67% (360) | transposase IS116/IS110/IS902 |
| M. thermoresistible (build 8) | TH_2233 | - | 1e-145 | 70.54% (353) | Transposase IS116/IS110/IS902 family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4491 | - | 1e-144 | 69.12% (353) | transposase, IS111A/IS1328/IS1533 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2037|M.bovis_AF2122/97 --------------------------------------------------
Rv2014|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1197|M.gilvum_PYR-GCK -MTLFIGDDWAEDHHDIHLMDAEGTRLASRRLPEGLAGIRGFHELVAAHA
TH_2233|M.thermoresistible__bu -------------------MDAEGAKLASRRLPEGLAGIGGFHDLVAAHA
Mvan_4491|M.vanbaalenii_PYR-1 --MIFVGDDWAEDHHDVYLMDESGQRLAARRLPEGLSGIRALHELIAGYA
MSMEG_1732|M.smegmatis_MC2_155 ---------------------------------------------MAAHC
MAV_0496|M.avium_104 -------------------------MVARGRVSNDAAGFAALLTLLAEAG
MMAR_3782|M.marinum_M MPTVWAGVDTGKRTHHCVVLDRNGGVLLSRPVDNDETALLELIEAVVGVA
Mb2037|M.bovis_AF2122/97 --------------------------------------------------
Rv2014|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1197|M.gilvum_PYR-GCK QDPTE-VVIGIETDRGLWVEALAAAGYEVFAVNPLAVARYRDRHQVSGAK
TH_2233|M.thermoresistible__bu EEPAQ-VVIGIETDRGLWVEALAAAGYQVFAINPLAVARYRDRHQVSGAK
Mvan_4491|M.vanbaalenii_PYR-1 EEPDQ-VIVGIETDRGLWVSALAAAGYRVWAINPMAAARYRDRHHVSGAK
MSMEG_1732|M.smegmatis_MC2_155 EDSEQ-VVVGIETDNGLWVQALHAVGYRVYGINPLSASRYRDRHCVSGAK
MAV_0496|M.avium_104 DSAAHPIPVGIETDRGLWVAALRETGRVIYPINPLAASRYRARHAVSGAK
MMAR_3782|M.marinum_M AGREVCWATDLNAGGAAMLITLLAAHDQQLLYIPGRIVHHAAATYRGDGK
Mb2037|M.bovis_AF2122/97 --------------------------------------------------
Rv2014|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1197|M.gilvum_PYR-GCK SDAADAKLLADLVRTDRHNHRPIAGDTPEVEAIKVLARAHQNLIWSRNRN
TH_2233|M.thermoresistible__bu SDAGDAKVLADLVRTDRHNHRPIAGDTPQVEAIKVLARAHQSLIWARTRH
Mvan_4491|M.vanbaalenii_PYR-1 SDASDAKLLADLVRTDRHNHREIAGDRPQAEAIKVLARSHQSLIWARTRH
MSMEG_1732|M.smegmatis_MC2_155 SDAGDAKILADLVRTDRHNHRQLADDSSAVHAIKVLARTHQSLVWARTRH
MAV_0496|M.avium_104 SDATDAVLLANIVRTDAAAHRPLPADTELAQAIRVLARAQQDAVWARQQI
MMAR_3782|M.marinum_M TDAKNARIIADQAR-MRTDLQPVRRADPIATDLRLLTSRRTDVVCDRVRA
Mb2037|M.bovis_AF2122/97 --------------------------------------------------
Rv2014|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1197|M.gilvum_PYR-GCK TNALRSALREYYPAALEAFASLSD-----RDALAILGRAPTPTDAARLSV
TH_2233|M.thermoresistible__bu TNTLRSALREYYPAALEAFDDLAD-----RDALAILGRAPTPTDATGLSL
Mvan_4491|M.vanbaalenii_PYR-1 ANMLRSGLREYYPAALEAFDSLTD-----SDALAILGRAPTPDQGARLSL
MSMEG_1732|M.smegmatis_MC2_155 SNALRAGLSQYYPAALAAFPDIDG-----RDALAVLQRAPDPSAGATLSL
MAV_0496|M.avium_104 GNQIRDLLKDFYPAAIAAFAGLPEGGLARADARTILAAAPTPTQAATLTP
MMAR_3782|M.marinum_M INRLRQTLLEYFPPLERAFDYSKS-----KAALTLLSRYQTPDSLRRIGP
Mb2037|M.bovis_AF2122/97 ---------------------MLHDRLTGAPRGATGDEGAANAHITRAMV
Rv2014|M.tuberculosis_H37Rv ---------------------MLHDRLTGAPRGATGDEGAANAHITRAMV
Mflv_1197|M.gilvum_PYR-GCK SKIRSALKAAGRQRNLDAKALEIQTALRSDQLAAAPAVTAAFGATTRAAV
TH_2233|M.thermoresistible__bu PKIRSALKTAGRQRNLDARALQIQTALRTEQLTAPASVTAAFGATTRATV
Mvan_4491|M.vanbaalenii_PYR-1 AKIGSALKSAGRQRNIESRAAEIQTALRGEHLTAPPAVAAAFGATTAAAV
MSMEG_1732|M.smegmatis_MC2_155 SKISSALKVAGRQRSIDARAREIQTALRSPQLHTSDQVVAALSASTTATV
MAV_0496|M.avium_104 ARLRRLLTKAGRRRHLDRDIERLRAVFTDTYLHQPPAVENAMGIQLAALL
MMAR_3782|M.marinum_M TRLATWLKARGCRNSATVAQTAVQAAQTQHTTLPTQTVGAQLVPR---LA
:: .
Mb2037|M.bovis_AF2122/97 AALTSVATQIKTLDAQIAEQLSLHADAHIFTSLPRSGTVRAARLLAEIGD
Rv2014|M.tuberculosis_H37Rv AALTSVATQIKTLDAQIAEQLSLHADAHIFTSLPRSGTVRAARLLAEIGD
Mflv_1197|M.gilvum_PYR-GCK AIITELNHHIADLEAELAAHFETHPDADIYLSLPGLGVILGARVLGEFGD
TH_2233|M.thermoresistible__bu GIITELNRQIDNLDAELTSHFEMHPDADIYRSLPGLGVILGARVLGEFGD
Mvan_4491|M.vanbaalenii_PYR-1 HVITALNDQIAELETALADHFEAHPDADIYRSLPGLGVILGARVLGEFGD
MSMEG_1732|M.smegmatis_MC2_155 AVLLVLNTQISELQTQLTDHFETHPDADIYLSLPGLGVILGARVLGEFGD
MAV_0496|M.avium_104 RQLEAACTAADELAEAAIAHFEQHPDAKIITSFPGLGMLAGARVLAEIGD
MMAR_3782|M.marinum_M AEITTIDAELAHVDNEITARFADHDSAEILTSMPGFGPVLAATFLAQIGG
: : :: * .*.* *:* * : .* .*.::*.
Mb2037|M.bovis_AF2122/97 CRARFPTPESLACLAGVAPSTRQSGKVKHVGFR-WAADKQLRDAVCDFAG
Rv2014|M.tuberculosis_H37Rv CRARFPTPESLACLAGVAPSTRQSGKVKHVGFR-WAADKQLRDAVCDFAG
Mflv_1197|M.gilvum_PYR-GCK DPNRYTTAKSRKNYAGTSPLTIASGKKRAVLAR-HVRNRRLYDAIDQWAF
TH_2233|M.thermoresistible__bu DPNRYTSAKSRKNYAGTSPLTIASGKKRAVLAR-HVRNRRLYDAIDQWAF
Mvan_4491|M.vanbaalenii_PYR-1 DPNRYTTAKCRKNYAGTSPLTIASGRKRAVLAR-HVRNKRLYDALDQWAF
MSMEG_1732|M.smegmatis_MC2_155 DPNRYTDAKSRKNYAATSQITVASGRRRAVIAR-HIKNRHLADAIDMWAY
MAV_0496|M.avium_104 DRTRFADARGLKAFAGSAPITRASGKKTVVLHR-HIKNRRLAAVGPIWAL
MMAR_3782|M.marinum_M NLDGFDTVDRLACVAGLAPVPRDSGRISGNLHRPRRFNRRLLRPCYLAAL
: *. : . **: * :::* *
Mb2037|M.bovis_AF2122/97 DSRRANLWAADRYNRAIARGHDHPHAVRILARAWLYAIWHCWQDGAAYHP
Rv2014|M.tuberculosis_H37Rv DSRRANLWAADRYNRAIARGHDHPHAVRILARAWLYAIWHCWQDGAAYHP
Mflv_1197|M.gilvum_PYR-GCK CALTNSPGARTFYDQHRAAGDLHHQALRALGNRLVGILHGCLRHHTPYSE
TH_2233|M.thermoresistible__bu CALTNSPGARAFYDQRRAADDLHHQALRALGNRLVGILHGCLRHHTRYDE
Mvan_4491|M.vanbaalenii_PYR-1 CTLTRSPGARAYYDQHRAAGDTHHQALRALANRLVGILHGCLRHHSPYDE
MSMEG_1732|M.smegmatis_MC2_155 SSLRASPGARTFYDQHRAAGDTHHQALRALGNRFIGILHGCLRHHTHYNE
MAV_0496|M.avium_104 GSLRASPGARRHYDARRAAGDWNHQAQRHLFNKFLGQLHHCLQTGRLYNE
MMAR_3782|M.marinum_M SSLKNSPASRTFYDRKRAEGKSHKQALIALARRRINVIWAMLRDHTHYHE
: . : *: * .. : :* * . : : : *
Mb2037|M.bovis_AF2122/97 ANHRALQ--------------ALLNQDQDRAA---
Rv2014|M.tuberculosis_H37Rv ANHRALQ--------------ALLNQDQDRAA---
Mflv_1197|M.gilvum_PYR-GCK HKAWAH----------------RQT--DSRAA---
TH_2233|M.thermoresistible__bu HTAWAH----------------RQTTADTQAA---
Mvan_4491|M.vanbaalenii_PYR-1 HKAWAH----------------RKP----AAA---
MSMEG_1732|M.smegmatis_MC2_155 HTAWARGIVNTCGSGCFRRPPFRRADRRLRAMLAG
MAV_0496|M.avium_104 HLAFPLNRPGFDGGS---CYWISTSGWSVRFVA--
MMAR_3782|M.marinum_M PDLVNTP----------------------LAA---