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KFVLAVHGTRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLTGVAYGPDSDEQINTVAAFVRNL TRAQNPLNLARAVKELFVEGWAEMGTTLTTLADGADLVMTGQTYHGVAANVAEYYDIPAAALHHFPMQVN GQIAIPSIPTPATLVRATMKVSWRLYAYVSKDADRAQRRELGLPPAPAPAVRRLAERGAPEIQAYDPVFF PGLAAEWSDRRPFVGPLTMELHSEPNEELESWIAAGTPPIYFGFGSTPVQTPVQTLAMISDVCAQLGERA LIYSPAANSTRIRHADHVKRVGLVNYSTILPKCRAVVHHGGAGTTAAGLRAGMPTLILWDVADQPIWAGA VQRLKVGSAKRFTNITRGSLLKELRSILAPECAARAREISTRMTRPTAAVTAAADLLEATARQTPGSTPS SSPGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1526c | - | - | 100% (426) | Probable glycosyltransferase |
| M. tuberculosis H37Rv | Rv1524 | - | e-134 | 58.55% (415) | glycosyltransferase |
| M. tuberculosis H37Rv | Rv2739c | - | 5e-07 | 27.97% (261) | alanine rich transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1553c | - | 0.0 | 100.00% (426) | glycosyltransferase |
| M. gilvum PYR-GCK | Mflv_0466 | - | 4e-07 | 23.64% (368) | glycosyl transferase family protein |
| M. leprae Br4923 | MLBr_02348 | - | 1e-124 | 54.48% (424) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_4694c | - | 1e-115 | 53.70% (419) | glycosyltransferase |
| M. marinum M | MMAR_2353 | - | 1e-113 | 50.49% (412) | UDP-glycosyltransferase |
| M. avium 104 | MAV_3258 | - | 1e-123 | 54.65% (419) | glycosyltransferase family protein 28 |
| M. smegmatis MC2 155 | MSMEG_4740 | - | 1e-123 | 55.10% (412) | glycosyltransferase family protein 28 |
| M. thermoresistible (build 8) | TH_1989 | - | 2e-39 | 50.34% (149) | Glycosyltransferase family protein 28 |
| M. ulcerans Agy99 | MUL_4949 | - | 1e-100 | 48.08% (416) | glycosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2401 | - | 5e-05 | 26.75% (243) | UDP-glucuronosyl/UDP-glucosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1526c|M.tuberculosis_H37Rv MKFVLAVHG-TRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLT
Mb1553c|M.bovis_AF2122/97 MKFVLAVHG-TRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLT
MSMEG_4740|M.smegmatis_MC2_155 MKFVVAIHG-TRGDIEPSATVATELRRRGHEVRMAVPPNLVPFVERIGLS
MAV_3258|M.avium_104 MRFALASYG-TRGDIEPSAAVGRELLRRGHDVRLAVPPELVGFVESTGLA
TH_1989|M.thermoresistible__bu --------------------------------------------------
MLBr_02348|M.leprae_Br4923 MKFTLAASG-SRGDVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLA
MMAR_2353|M.marinum_M MKFALAING-TRGDVEPCAALGRELSRRGHEVRVAVPPNLTGLAAAAGLE
MUL_4949|M.ulcerans_Agy99 MKAVVASYG-SRGDVEPCAAAARELLRRGHEVRVAAPPNLVGFLESAGLT
MAB_4694c|M.abscessus_ATCC_199 MKFVLASYG-TRGDIEPCAAVGRELIRRGHDVCMAVPPDLIGFVEAAGPT
Mvan_2401|M.vanbaalenii_PYR-1 MRVAVVAGP-DPGHAFPAIALCLRFLAAGDHPTLLTGTKWLDTARREGVD
Mflv_0466|M.gilvum_PYR-GCK MAVILAYTAPALGHLFPFCAVLQELARRGHDIHVRTLAAGLQICRDEGFT
Rv1526c|M.tuberculosis_H37Rv GVAYGPDSDEQINTV----------AAFVRNLTRAQNPLNLARAVKELFV
Mb1553c|M.bovis_AF2122/97 GVAYGPDSDEQINTV----------AAFVRNLTRAQNPLNLARAVKELFV
MSMEG_4740|M.smegmatis_MC2_155 AESYGVDSQQQLD------------ADTFRDFWKIRNPVKAIREGREYMV
MAV_3258|M.avium_104 AVPYGPNVQEFLDEEFL---------RNMWRDFFRN-PIRLVLKVWDPII
TH_1989|M.thermoresistible__bu --------------------------------------------------
MLBr_02348|M.leprae_Br4923 AVAYGPDTQEFLARDTY---------SQWRQWWKILPPIKALQQ----LR
MMAR_2353|M.marinum_M AVPYGPDTDELLNDE-----------DNLQEFWKPQTSIKLVREGISDLR
MUL_4949|M.ulcerans_Agy99 TVAYGPDSHQQMGPAPN---------LVGDLAATAQHPITMVPKLIEHLT
MAB_4694c|M.abscessus_ATCC_199 AVPYGPDLRNVLDAHREF------WTHFFRNFWRVQELIEKRREVVEPFL
Mvan_2401|M.vanbaalenii_PYR-1 AVELLGLDPTADDDDTD---------AGAKIHHRAARMAVLNKDPIAALA
Mflv_0466|M.gilvum_PYR-GCK AAAVDPRIEAIQADDTLTGTVRAAADTVEVLTARAPLEVADLLSAVESVQ
Rv1526c|M.tuberculosis_H37Rv EGWAEMGTTLTTLADGADLVMTGQTYHGVAANVAEYYDIPAAALHHFPMQ
Mb1553c|M.bovis_AF2122/97 EGWAEMGTTLTTLADGADLVMTGQTYHGVAANVAEYYDIPAAALHHFPMQ
MSMEG_4740|M.smegmatis_MC2_155 GGWAEMSATVAALADGADVLLTGTTYQEVVANVAESERIPLAALHYFPHR
MAV_3258|M.avium_104 KYWAEASATLKSVAEGADLLSTGLNFEQAAANVAEYYDIPLASLHHFPMR
TH_1989|M.thermoresistible__bu --------------------------------------------------
MLBr_02348|M.leprae_Br4923 QAWADMATDLKSLADGADLVMTGVVYQGVVANVAEYYGIPFGVLHFVPAR
MMAR_2353|M.marinum_M QAWSDMAGTLKTLADGADLVLTGMIHQGIALNAAEYYGIPLATMHFLPSR
MUL_4949|M.ulcerans_Agy99 RVNAAKSETLTALADGADLLVVGFNEQAVAANVAEYFGIPLAGLHFFPA-
MAB_4694c|M.abscessus_ATCC_199 LCWKDIVGTLTSLAEGADLLFTGVNFEDAAGNVAEYHDIPLATLHLFPLR
Mvan_2401|M.vanbaalenii_PYR-1 PDLVISDSITTCGGLAADLLGLPWAELNTHPLYHPSKGLPPIGSGLAPGT
Mflv_0466|M.gilvum_PYR-GCK PDVVIVDANCWGAMSVAETLGRPWVVLSPFTPYLRSPGAPPFGPGATPWP
Rv1526c|M.tuberculosis_H37Rv VNGQIAIPSIPTPATLVRATMKVSWRLYAYVSKDADRAQRRELGLPPAPA
Mb1553c|M.bovis_AF2122/97 VNGQIAIPSIPTPATLVRATMKVSWRLYAYVSKDADRAQRRELGLPPAPA
MSMEG_4740|M.smegmatis_MC2_155 ANSQILP--IRLPRRIVEPMWAVAEWGYWQILKSAEDAQRRELGLAPARS
MAV_3258|M.avium_104 ANGQLVP---NMPSPLVRSTMTAIEWLFWRSTKKVDNAQRRQLGLPKATR
TH_1989|M.thermoresistible__bu --------------------------------------------------
MLBr_02348|M.leprae_Br4923 VNGKIIP---SLPSPLNRAILATVWRAHWLLAKKPEDAQRRELGLPKATS
MMAR_2353|M.marinum_M VNSRVIP---ILSPRLNRSVISALWWVHWRVTKNPEEAQRRELGMAKASS
MUL_4949|M.ulcerans_Agy99 -------------PALPAGMLST------LATKAADDAQRQALGLPPASE
MAB_4694c|M.abscessus_ATCC_199 SNGQFVP---FLPARLGRSAMKAGEWLAWQNAKKVERVQREELRLPRATK
Mvan_2401|M.vanbaalenii_PYR-1 G----------LRGRLRDAVLRALSARSWRAGLRQRSEARVGIGLPAADP
Mflv_0466|M.gilvum_PYR-GCK G---------PLGRIRDWGIGLVTTAVFDRPFARQIAPLRRALGLTPVRT
Rv1526c|M.tuberculosis_H37Rv PAVRRLAERGAPEIQAYDPVFFPGLAAEWS---DRRPFVGPLTMELHSEP
Mb1553c|M.bovis_AF2122/97 PAVRRLAERGAPEIQAYDPVFFPGLAAEWS---DRRPFVGPLTMELHSEP
MSMEG_4740|M.smegmatis_MC2_155 SSVNRIVSSGTLEIQAYDEVFFPGLRQEWR---GTRPFVGALTLELPTDT
MAV_3258|M.avium_104 RSQRRIAERGWLEIQAYDEVCFPGLAAEWAHWGDRRPFVGALTMELPTES
TH_1989|M.thermoresistible__bu --------------------------------------------------
MLBr_02348|M.leprae_Br4923 LSTRRIVKRGALEIQAYDELCFPGLAAEWAEYGDRRPFVGALTLELPTAA
MMAR_2353|M.marinum_M SSTSRILKGRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTES
MUL_4949|M.ulcerans_Agy99 SVPQRVAEQGSLEIQAYDQIVLPGPPGRWVQADGRHPFIGALTLQSPTDD
MAB_4694c|M.abscessus_ATCC_199 PSPWRITERRALEIQAYDGMCFPGLATEWGGFSSNRPFVGALTLDLPTDF
Mvan_2401|M.vanbaalenii_PYR-1 GPVCRLIAT------------LPALEVPRPDWPADAVVVGPLHFEPTTHV
Mflv_0466|M.gilvum_PYR-GCK AGDLLLRAPAVLVATG------KPLEYPHTDWGETVTMIGPAVFEPRAAQ
Rv1526c|M.tuberculosis_H37Rv NEELESWIAAGTPPIYFGFGSTPVQTPVQTLAMISDVCAQLGERALIYSP
Mb1553c|M.bovis_AF2122/97 NEELESWIAAGTPPIYFGFGSTPVQTPVQTLAMISDVCAQLGERALIYSP
MSMEG_4740|M.smegmatis_MC2_155 DDDVTAWAASGKPPIYFGFGSMPVQSPADAVTMISSVCTRLGERALISSG
MAV_3258|M.avium_104 DDDVASWIAAGTPPICFGSGSIPLESPTATVEMIGAASARLGERALICFG
TH_1989|M.thermoresistible__bu --------------------------------MFASVCSRLGERALICAG
MLBr_02348|M.leprae_Br4923 DNEVLSWIAAGTPPIYFGFGSMPIVSPTDTVAMIAAACADLGERALISVK
MMAR_2353|M.marinum_M DNEVLSWIASGTPPIYFGFGSMPVESPAATIAMISAACAELGERALICTG
MUL_4949|M.ulcerans_Agy99 DDAILAWIAEGAPPIYFGFGSTPLTSPAEQFAMISAACAQLGERALICAG
MAB_4694c|M.abscessus_ATCC_199 DEEVAGWIASGTPPIFFGFGSLPVESADQTFAMISAACAQLGERALVCSA
Mvan_2401|M.vanbaalenii_PYR-1 LRLPAGDGPVVVVAPSTATTGAVGLAELALATLVPGEVLPEGARVVVSRL
Mflv_0466|M.gilvum_PYR-GCK R---PSWLDHIDDPIVLVTTSSVGQSDAALVETAVEALRDEPVHLVVTAP
: ::
Rv1526c|M.tuberculosis_H37Rv AANSTRIRHADHVKRVGLVNYSTILPKCRAVVHHGGAGTTAAGLRAGMPT
Mb1553c|M.bovis_AF2122/97 AANSTRIRHADHVKRVGLVNYSTILPKCRAVVHHGGAGTTAAGLRAGMPT
MSMEG_4740|M.smegmatis_MC2_155 AWNLDAIPESDHVKVVGAVNHAKIFPLCRAVVHHGGAGTTAAGLRAARPT
MAV_3258|M.avium_104 GTDVRGVPRFDHVKVVGPVNYASVFPACRAVVHHGGSGTTAASLRAGIPT
TH_1989|M.thermoresistible__bu GTDIDGVPEYGHVKVVGAVNYARVFPACRAIVHHGGSGTTAAVLRAGVPS
MLBr_02348|M.leprae_Br4923 PKDLTQVPKFDHVKIVTSVSHAAVFPACRAVVHHGGAGTTAASLRAGVPT
MMAR_2353|M.marinum_M SNDLGGLQAPENVKLVSGVSHAAVFPACRAVVHHGGAGTTAAGMRAGIPT
MUL_4949|M.ulcerans_Agy99 PNDFGQMPHSHQVMVAPAVNHAAVFPACRAIVHHGGAGTTAAGLRAGIPM
MAB_4694c|M.abscessus_ATCC_199 GSGFGDAPDAENIKIVHAMNYSAAFPKCRAVVHHGGTGTTAAGLRAGAPT
Mvan_2401|M.vanbaalenii_PYR-1 EGPDAEVPP---WAVVGLGRQDELLAKADLLICGGGHGTVAKSLLAGVPM
Mflv_0466|M.gilvum_PYR-GCK TGDVDVMTRPG-VTQVRFAPHSMLLEHAVCVITHGGMGVTQKALARGVPV
. : . :: ** *.. : . *
Rv1526c|M.tuberculosis_H37Rv LILWDVADQPIWAGAVQRLKVGSAKRFTNITRGSLLKELRSILA-PECAA
Mb1553c|M.bovis_AF2122/97 LILWDVADQPIWAGAVQRLKVGSAKRFTNITRGSLLKELRSILA-PECAA
MSMEG_4740|M.smegmatis_MC2_155 LILWVGADQPVWAAAVKRLQAGTAERFSKVTPDSLLAGLQTVLT-PRAAL
MAV_3258|M.avium_104 LALWSSADQPYWAAQIKRLKVGTARRFSATTSETLAADLRTILA-PDYAT
TH_1989|M.thermoresistible__bu LVTWSSADQPYWGNQVKRLKVGTSRRFSHTTPDTLVADLRRILT-PDYAV
MLBr_02348|M.leprae_Br4923 LILWIFIEQPVWAAQIKRLKVGAGRRFSATTQRSLAADLRTILA-PQYAT
MMAR_2353|M.marinum_M LILWIWIEQPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILG-PDYVA
MUL_4949|M.ulcerans_Agy99 LIRWLWLDQPIWAAGIEELGVGVGQPFSAATSESLAAGLGSILA-AQYIA
MAB_4694c|M.abscessus_ATCC_199 LILSTDLDQTLWGRRIKELKVGTTRRFSSTTVKTLTSDLRAILD-PQCAA
Mvan_2401|M.vanbaalenii_PYR-1 VVVPGGGDQ--WEIANRLVRQGSAQLVRPLTGSTLTAAVQEVLGSPGYRE
Mflv_0466|M.gilvum_PYR-GCK CVVPFGRDQFEVARRVELAGCGTRLPAGKLSVGRLRTAVKTAATMTGGAA
:* . * : * : .
Rv1526c|M.tuberculosis_H37Rv RAREISTRMTRPTAAVTAAADLLEATARQTPGSTPSSSPGR
Mb1553c|M.bovis_AF2122/97 RAREISTRMTRPTAAVTAAADLLEATARQTPGSTPSSSPGR
MSMEG_4740|M.smegmatis_MC2_155 RARQIADEMTTPADSVRMTADLLEAAAARP---MPA-----
MAV_3258|M.avium_104 RARDLAARMTKPAESIETTADLLEEAARRKT-LG-------
TH_1989|M.thermoresistible__bu RARAVAARMTDPADSVVRAADLFETAVECAPGVAHRE----
MLBr_02348|M.leprae_Br4923 RAREVANRMSKPDESVNAAADLLEDKASRNKSRTRYQDC--
MMAR_2353|M.marinum_M RARTIANEMSKPGESATRAADLLENEVSVS-----------
MUL_4949|M.ulcerans_Agy99 RARTVADQMTPPAHSIAMAADLLEHTAHVDRRS--------
MAB_4694c|M.abscessus_ATCC_199 RARELATHMTKPIESVTKTADLVEGLAASYRCGSRA-----
Mvan_2401|M.vanbaalenii_PYR-1 AARRAGAGVADVADPVRVCHAALGAPA--------------
Mflv_0466|M.gilvum_PYR-GCK RVAAGFAATGGVARGADVVESRLVARCALPEEQ--------
. .