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MRHTRFHPIKLAWITAVVAGLMVGVATPADAEPGQWDPTLPALVSAGAPGDPLAVANASLQATAQATQTT LDLGRQFLGGLGINLGGPAASAPSAATTGASRIPRANARQAVEYVIRRAGSQMGVPYSWGGGSLQGPSKG VDSGANTVGFDCSGLVRYAFAGVGVLIPRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQ MLEASGSAGKVTVSPVRKAGMTPFVTRIIEY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1478 | - | - | 100% (241) | HYPOTHETICAL INVASION PROTEIN |
| M. tuberculosis H37Rv | Rv1477 | - | 7e-70 | 60.10% (208) | invasion protein |
| M. tuberculosis H37Rv | Rv1566c | - | 7e-39 | 49.08% (163) | inv protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1514 | - | 1e-139 | 100.00% (241) | invasion protein |
| M. gilvum PYR-GCK | Mflv_2843 | - | 1e-79 | 63.09% (233) | NLP/P60 protein |
| M. leprae Br4923 | MLBr_01811 | - | 1e-106 | 77.08% (240) | putative exported p60 protein homologue |
| M. abscessus ATCC 19977 | MAB_2727c | - | 3e-58 | 56.94% (209) | invasion protein Inv2 |
| M. marinum M | MMAR_2285 | iipB | 1e-115 | 83.40% (241) | invasion and intracellular persistence protein, IipB |
| M. avium 104 | MAV_3300 | - | 1e-106 | 78.05% (246) | invasin 1 |
| M. smegmatis MC2 155 | MSMEG_3146 | - | 9e-83 | 66.22% (225) | invasin 1 |
| M. thermoresistible (build 8) | TH_4058 | - | 6e-82 | 65.47% (223) | PUTATIVE NLP/P60 protein |
| M. ulcerans Agy99 | MUL_1487 | inv2 | 1e-116 | 84.23% (241) | invasion protein Inv2 |
| M. vanbaalenii PYR-1 | Mvan_2748 | - | 4e-81 | 62.93% (232) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1478|M.tuberculosis_H37Rv -------MRHT----------------RFHPIKLAWITAVVAGLMVGVAT
Mb1514|M.bovis_AF2122/97 -------MRHT----------------RFHPIKLAWITAVVAGLMVGVAT
MMAR_2285|M.marinum_M MSSYRGPMRYK----------------RFRLLGLAWITLAVAALLVVVSA
MUL_1487|M.ulcerans_Agy99 -------MRYK----------------RFRLLGLAWITLAVAALMVVVSA
MLBr_01811|M.leprae_Br4923 -------MRHK----------------NFRLINLAGLTAMVAGLIIVVTI
MAV_3300|M.avium_104 -------MRRN----------------RFRLIVFAWITAMVTGLMFSVAP
Mflv_2843|M.gilvum_PYR-GCK ---MGLHVRSKGAAIASTDRCDPAILVAGRVRRLPGVIAIVVLLFLACAP
MSMEG_3146|M.smegmatis_MC2_155 -----MVLR------------------------ALIAVVAVAFAAVGLVA
Mvan_2748|M.vanbaalenii_PYR-1 ----MIALRR-----------------------FVIALVTAAALLAGAVA
TH_4058|M.thermoresistible__bu ---VVILLRSK----------------TFRLLRPLIPAILGLGVLIAAAG
MAB_2727c|M.abscessus_ATCC_199 -MQGLFLLRS------------------AIAVTIAIALVLFMGVPRAAAD
:*
Rv1478|M.tuberculosis_H37Rv P--ADAEPGQWDPTLPALVSAGAPGDP-LAVANASLQAT-AQATQTTLDL
Mb1514|M.bovis_AF2122/97 P--ADAEPGQWDPTLPALVSAGAPGDP-LAVANASLQAT-AQATQTTLDL
MMAR_2285|M.marinum_M P--ADADPGGWDPTLPATASAGAPGDA-LAMANASLQAT-AQATQTTLDL
MUL_1487|M.ulcerans_Agy99 P--ADADPGGWDPTLPATASAGAPGDA-LAMANASLQAT-AQATQTTLDL
MLBr_01811|M.leprae_Br4923 P--ATADPGQWDPTLPAAVSAGAPGDP-LAVANASLQVT-AQATQTTLDL
MAV_3300|M.avium_104 TPAALADPGEWDPTLPAQISAGAPGDP-LAVANASLQAT-AQATQTTLNL
Mflv_2843|M.gilvum_PYR-GCK VASAQPAAGPWDPLLPKIPSAGAPGDP-VAIANASLQAT-AMATQTAMNM
MSMEG_3146|M.smegmatis_MC2_155 PAGAAPEDGQWDPTLPKLISAGAPGDP-LAIANASLEAT-AQATQVTMGL
Mvan_2748|M.vanbaalenii_PYR-1 PASAQPESGQWDPTLPKLISAGAPGDP-LAIANASLAAT-AQATQVTMDL
TH_4058|M.thermoresistible__bu PATAAPDDGQWDPTLPKLISAGAPGDP-LAIANASLAAT-AQATQVTMDL
MAB_2727c|M.abscessus_ATCC_199 DNPLGPNVGTAFLNALGLNPTGGQYDPTLPFAGPSQGADPAKIMNGVMGV
. * .:*. *. :..*..* . * : .:.:
Rv1478|M.tuberculosis_H37Rv GRQFLGGLGINLGGPAASAPSAATTG-ASRIPRANARQAVEYVIRRAGSQ
Mb1514|M.bovis_AF2122/97 GRQFLGGLGINLGGPAASAPSAATTG-ASRIPRANARQAVEYVIRRAGSQ
MMAR_2285|M.marinum_M GRQFLGGLGINLGG--SPAPSAANTG-ANRIPRVYGQQALEYVIRRGGSQ
MUL_1487|M.ulcerans_Agy99 GRQFLGGLGINLGG--SPAPSAANTG-ANRIPRVYGRQALEYVIRRGGSQ
MLBr_01811|M.leprae_Br4923 GKQFLGRLGINFGG-DPSNAATTSSNPGGRIPRVYGGQAIEYVIKRGGAQ
MAV_3300|M.avium_104 GKQFLGGLGINLGGNDAPAAAATPSNPGGKIPRVYGRQAIEYVIKRMGSQ
Mflv_2843|M.gilvum_PYR-GCK GRSFLSSLGI-------VSPAADPST-SVRGNRVNGAQAIEYVIRRAGTQ
MSMEG_3146|M.smegmatis_MC2_155 GRKFLASLGLVEDTP---AAAGVAPG------RVRGPQAIEYVIRRGGTQ
Mvan_2748|M.vanbaalenii_PYR-1 GRKFLQTIGLAPKD----APAGVAPG------VVRGPAAIEYAIRRGGTQ
TH_4058|M.thermoresistible__bu GRKFLASIGLGGSQ----PVSSVAPG------RVRGPQAIEYVIRRGASQ
MAB_2727c|M.abscessus_ATCC_199 GQTALGALGIGGNS----ASAGAGRP------LVYGRAAVERVIQRGGTQ
*: * :*: : . . *:* .*:* .:*
Rv1478|M.tuberculosis_H37Rv MGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAFAGVGVLIPRFSG
Mb1514|M.bovis_AF2122/97 MGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAFAGVGVLIPRFSG
MMAR_2285|M.marinum_M MGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLMRYAFAGVGVLIPRYSG
MUL_1487|M.ulcerans_Agy99 MGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLMRYAFAGVGVLIPRYSG
MLBr_01811|M.leprae_Br4923 IGVPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYAFAGVGVLIPRFSG
MAV_3300|M.avium_104 MGVPYSWGGGSLDGPSKGVGDGANITGFDCSGLMRYGFAGVGVLIPRFSG
Mflv_2843|M.gilvum_PYR-GCK IGVPYSWGGGSLTGPSRGVDQGAGTVGFDCSGLTRFAFAGVGVLLPRWSG
MSMEG_3146|M.smegmatis_MC2_155 MGVPYSWGGGKPNGPSRGIDSGANTVGFDCSGFTQFSFAGVGVLIPKYSG
Mvan_2748|M.vanbaalenii_PYR-1 IGTPYSWGGGKPNGPSRGIDSGANTVGYDCSGFTQFSYAGVGVLIPKYSG
TH_4058|M.thermoresistible__bu LGVPYSWGGGKPSGPSTGVGSGANTVGFDCSGFTQFAFAGVGVLIPKYSG
MAB_2727c|M.abscessus_ATCC_199 LGVPYSWGGGTVRGPSGGVDYDSGKVGYDCSGFTMFSYAAAGVKLPKYSG
:*.*******. *** *:. .:. .*:****: :.:*..** :*::**
Rv1478|M.tuberculosis_H37Rv DQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGSAGKVT
Mb1514|M.bovis_AF2122/97 DQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGSAGKVT
MMAR_2285|M.marinum_M DQYNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNGQMLEASGSAGKVT
MUL_1487|M.ulcerans_Agy99 DQYNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNGQMLEASGSAGKVT
MLBr_01811|M.leprae_Br4923 DQYNAGRHLTPDQAKRGDLIFYGPGGGQHVTMYLGNGQMLEASSSVGKVT
MAV_3300|M.avium_104 DQYNAGRHIPQDQARRGDLIFYGPGGSQHVTMYLGNGQMLEASGSAGKVT
Mflv_2843|M.gilvum_PYR-GCK DQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGGQMIEAQQTGVPIK
MSMEG_3146|M.smegmatis_MC2_155 DQYNTGRKVPVNQAKRGDLLFWGPGGSQHVALYLGGGKMLEASGSAGKVT
Mvan_2748|M.vanbaalenii_PYR-1 DQYNTGRKVPVQQAKRGDLLFWGPGGSQHVAIYLGGGKMLESSGSAGKVT
TH_4058|M.thermoresistible__bu DQYNTGRKVPVSQAKRGDLLFWGPGGSQHVALYLGNGQMLEASGSAGKVV
MAB_2727c|M.abscessus_ATCC_199 DQYNAGQKVPVAQAKRGDLLFYGPGGSQHVVIYLGNGQMLEASGSAGKVT
***::*:::. :*:****:*:****.** .:***.*:*:*:. : :
Rv1478|M.tuberculosis_H37Rv VSPVRKAGMTPFVTRIIEY
Mb1514|M.bovis_AF2122/97 VSPVRKAGMTPFVTRIIEY
MMAR_2285|M.marinum_M VSPVRKAGMTPFVTRIIEY
MUL_1487|M.ulcerans_Agy99 VSPVRKAGMTPFVTRIIEY
MLBr_01811|M.leprae_Br4923 VSSVRKAGMTPFVTRIIES
MAV_3300|M.avium_104 VSPVRKPGMTPFLTRIIEY
Mflv_2843|M.gilvum_PYR-GCK VSPVRTGGMTPYVVRIIES
MSMEG_3146|M.smegmatis_MC2_155 VSPVRMSGLQPYAARIIES
Mvan_2748|M.vanbaalenii_PYR-1 VSPVRMSGLQPFVARIIES
TH_4058|M.thermoresistible__bu AGPVRTAGLQPYAARIIET
MAB_2727c|M.abscessus_ATCC_199 VSPVRTGGMTPYAVRIIAW
...** *: *: .***