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MRYKRFRLLGLAWITLAVAALMVVVSAPADADPGGWDPTLPATASAGAPGDALAMANASLQATAQATQTT LDLGRQFLGGLGINLGGSPAPSAANTGANRIPRVYGRQALEYVIRRGGSQMGVPYSWGGGSLQGPSKGVD SGANTVGFDCSGLMRYAFAGVGVLIPRYSGDQYNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNGQML EASGSAGKVTVSPVRKAGMTPFVTRIIEY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1487 | inv2 | - | 100% (239) | invasion protein Inv2 |
| M. ulcerans Agy99 | MUL_1486 | - | 4e-72 | 63.41% (205) | cell wall-associated hydrolase |
| M. ulcerans Agy99 | MUL_1557 | - | 3e-38 | 48.19% (166) | inv protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1514 | - | 1e-116 | 84.23% (241) | invasion protein |
| M. gilvum PYR-GCK | Mflv_0902 | - | 6e-77 | 63.72% (226) | NLP/P60 protein |
| M. tuberculosis H37Rv | Rv1478 | - | 1e-116 | 84.23% (241) | invasion protein |
| M. leprae Br4923 | MLBr_01811 | - | 1e-109 | 79.25% (241) | putative exported p60 protein homologue |
| M. abscessus ATCC 19977 | MAB_2727c | - | 3e-58 | 50.41% (246) | invasion protein Inv2 |
| M. marinum M | MMAR_2285 | iipB | 1e-136 | 99.16% (239) | invasion and intracellular persistence protein, IipB |
| M. avium 104 | MAV_3300 | - | 1e-108 | 80.33% (244) | invasin 1 |
| M. smegmatis MC2 155 | MSMEG_3146 | - | 2e-81 | 64.47% (228) | invasin 1 |
| M. thermoresistible (build 8) | TH_4058 | - | 2e-81 | 63.75% (240) | PUTATIVE NLP/P60 protein |
| M. vanbaalenii PYR-1 | Mvan_2748 | - | 6e-78 | 63.11% (225) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1487|M.ulcerans_Agy99 ---------------------MRYKRFRLLGLAWITLAVAALMVVVSAP-
MMAR_2285|M.marinum_M --------------MSSYRGPMRYKRFRLLGLAWITLAVAALLVVVSAP-
Mb1514|M.bovis_AF2122/97 ---------------------MRHTRFHPIKLAWITAVVAGLMVGVATP-
Rv1478|M.tuberculosis_H37Rv ---------------------MRHTRFHPIKLAWITAVVAGLMVGVATP-
MLBr_01811|M.leprae_Br4923 ---------------------MRHKNFRLINLAGLTAMVAGLIIVVTIP-
MAV_3300|M.avium_104 ---------------------MRRNRFRLIVFAWITAMVTGLMFSVAPTP
Mflv_0902|M.gilvum_PYR-GCK MTSDVRSRSAAIAGADRSEPAMRVAR-RVRRLPGVLSIVVLLFVACAPVA
MSMEG_3146|M.smegmatis_MC2_155 -------------------MVLR--------ALIAVVAVAFAAVGLVAPA
Mvan_2748|M.vanbaalenii_PYR-1 ------------------MIALRR-------FVIALVTAAALLAGAVAPA
TH_4058|M.thermoresistible__bu -----------------VVILLRSKTFRLLRPLIPAILGLGVLIAAAGPA
MAB_2727c|M.abscessus_ATCC_199 -----------------MQGLFLLRSAIAVTIAIALVLFMGVPRAAADDN
:
MUL_1487|M.ulcerans_Agy99 -ADADPGGWDPTLPATASAGAPGDA-LAMANASLQAT-AQATQTTLDLGR
MMAR_2285|M.marinum_M -ADADPGGWDPTLPATASAGAPGDA-LAMANASLQAT-AQATQTTLDLGR
Mb1514|M.bovis_AF2122/97 -ADAEPGQWDPTLPALVSAGAPGDP-LAVANASLQAT-AQATQTTLDLGR
Rv1478|M.tuberculosis_H37Rv -ADAEPGQWDPTLPALVSAGAPGDP-LAVANASLQAT-AQATQTTLDLGR
MLBr_01811|M.leprae_Br4923 -ATADPGQWDPTLPAAVSAGAPGDP-LAVANASLQVT-AQATQTTLDLGK
MAV_3300|M.avium_104 AALADPGEWDPTLPAQISAGAPGDP-LAVANASLQAT-AQATQTTLNLGK
Mflv_0902|M.gilvum_PYR-GCK SAQPAAGPWDPLLPKVASAGAPGDP-LAIANASLQAT-AMATQTAMSMGR
MSMEG_3146|M.smegmatis_MC2_155 GAAPEDGQWDPTLPKLISAGAPGDP-LAIANASLEAT-AQATQVTMGLGR
Mvan_2748|M.vanbaalenii_PYR-1 SAQPESGQWDPTLPKLISAGAPGDP-LAIANASLAAT-AQATQVTMDLGR
TH_4058|M.thermoresistible__bu TAAPDDGQWDPTLPKLISAGAPGDP-LAIANASLAAT-AQATQVTMDLGR
MAB_2727c|M.abscessus_ATCC_199 PLGPNVGTAFLNALGLNPTGGQYDPTLPFAGPSQGADPAKIMNGVMGVGQ
. * .:*. *. *..*..* . * : .:.:*:
MUL_1487|M.ulcerans_Agy99 QFLGGLGINLGG--SPAPSAANTG-ANRIPRVYGRQALEYVIRRGGSQMG
MMAR_2285|M.marinum_M QFLGGLGINLGG--SPAPSAANTG-ANRIPRVYGQQALEYVIRRGGSQMG
Mb1514|M.bovis_AF2122/97 QFLGGLGINLGGPAASAPSAATTG-ASRIPRANARQAVEYVIRRAGSQMG
Rv1478|M.tuberculosis_H37Rv QFLGGLGINLGGPAASAPSAATTG-ASRIPRANARQAVEYVIRRAGSQMG
MLBr_01811|M.leprae_Br4923 QFLGRLGINFGG-DPSNAATTSSNPGGRIPRVYGGQAIEYVIKRGGAQIG
MAV_3300|M.avium_104 QFLGGLGINLGGNDAPAAAATPSNPGGKIPRVYGRQAIEYVIKRMGSQMG
Mflv_0902|M.gilvum_PYR-GCK NFLSSLGI-------VSPAADPST-SVRGNRVNGAQAIEYVIRRAGTQIG
MSMEG_3146|M.smegmatis_MC2_155 KFLASLGLVEDTP---AAAGVAPG------RVRGPQAIEYVIRRGGTQMG
Mvan_2748|M.vanbaalenii_PYR-1 KFLQTIGLAPKD----APAGVAPG------VVRGPAAIEYAIRRGGTQIG
TH_4058|M.thermoresistible__bu KFLASIGLGGSQ----PVSSVAPG------RVRGPQAIEYVIRRGASQLG
MAB_2727c|M.abscessus_ATCC_199 TALGALGIGGNS----ASAGAGRP------LVYGRAAVERVIQRGGTQLG
* :*: : . . *:* .*:* .:*:*
MUL_1487|M.ulcerans_Agy99 VPYSWGGGSLQGPSKGVDSGANTVGFDCSGLMRYAFAGVGVLIPRYSGDQ
MMAR_2285|M.marinum_M VPYSWGGGSLQGPSKGVDSGANTVGFDCSGLMRYAFAGVGVLIPRYSGDQ
Mb1514|M.bovis_AF2122/97 VPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAFAGVGVLIPRFSGDQ
Rv1478|M.tuberculosis_H37Rv VPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAFAGVGVLIPRFSGDQ
MLBr_01811|M.leprae_Br4923 VPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYAFAGVGVLIPRFSGDQ
MAV_3300|M.avium_104 VPYSWGGGSLDGPSKGVGDGANITGFDCSGLMRYGFAGVGVLIPRFSGDQ
Mflv_0902|M.gilvum_PYR-GCK VPYSWGGGSLTGPSRGVDQGAGTVGFDCSGLTRFAFAGVGVLLPRWSGDQ
MSMEG_3146|M.smegmatis_MC2_155 VPYSWGGGKPNGPSRGIDSGANTVGFDCSGFTQFSFAGVGVLIPKYSGDQ
Mvan_2748|M.vanbaalenii_PYR-1 TPYSWGGGKPNGPSRGIDSGANTVGYDCSGFTQFSYAGVGVLIPKYSGDQ
TH_4058|M.thermoresistible__bu VPYSWGGGKPSGPSTGVGSGANTVGFDCSGFTQFAFAGVGVLIPKYSGDQ
MAB_2727c|M.abscessus_ATCC_199 VPYSWGGGTVRGPSGGVDYDSGKVGYDCSGFTMFSYAAAGVKLPKYSGDQ
.*******. *** *:. .:. .*:****: :.:*..** :*::****
MUL_1487|M.ulcerans_Agy99 YNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNGQMLEASGSAGKVTVS
MMAR_2285|M.marinum_M YNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNGQMLEASGSAGKVTVS
Mb1514|M.bovis_AF2122/97 YNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGSAGKVTVS
Rv1478|M.tuberculosis_H37Rv YNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGSAGKVTVS
MLBr_01811|M.leprae_Br4923 YNAGRHLTPDQAKRGDLIFYGPGGGQHVTMYLGNGQMLEASSSVGKVTVS
MAV_3300|M.avium_104 YNAGRHIPQDQARRGDLIFYGPGGSQHVTMYLGNGQMLEASGSAGKVTVS
Mflv_0902|M.gilvum_PYR-GCK YDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGGQMLEAQQTGVPIKIS
MSMEG_3146|M.smegmatis_MC2_155 YNTGRKVPVNQAKRGDLLFWGPGGSQHVALYLGGGKMLEASGSAGKVTVS
Mvan_2748|M.vanbaalenii_PYR-1 YNTGRKVPVQQAKRGDLLFWGPGGSQHVAIYLGGGKMLESSGSAGKVTVS
TH_4058|M.thermoresistible__bu YNTGRKVPVSQAKRGDLLFWGPGGSQHVALYLGNGQMLEASGSAGKVVAG
MAB_2727c|M.abscessus_ATCC_199 YNAGQKVPVAQAKRGDLLFYGPGGSQHVVIYLGNGQMLEASGSAGKVTVS
*::*:::. :*:****:*:****.** .:***.*:***:. : : .
MUL_1487|M.ulcerans_Agy99 PVRKAGMTPFVTRIIEY
MMAR_2285|M.marinum_M PVRKAGMTPFVTRIIEY
Mb1514|M.bovis_AF2122/97 PVRKAGMTPFVTRIIEY
Rv1478|M.tuberculosis_H37Rv PVRKAGMTPFVTRIIEY
MLBr_01811|M.leprae_Br4923 SVRKAGMTPFVTRIIES
MAV_3300|M.avium_104 PVRKPGMTPFLTRIIEY
Mflv_0902|M.gilvum_PYR-GCK PVRTSGMTPNVVRIIES
MSMEG_3146|M.smegmatis_MC2_155 PVRMSGLQPYAARIIES
Mvan_2748|M.vanbaalenii_PYR-1 PVRMSGLQPFVARIIES
TH_4058|M.thermoresistible__bu PVRTAGLQPYAARIIET
MAB_2727c|M.abscessus_ATCC_199 PVRTGGMTPYAVRIIAW
.** *: * .***