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M. tuberculosis H37Rv Rv1566c (-)

annotation: Possible inv protein
coordinates: 1773928 - 1774620
length: 230

KRSMKSGSFAIGLAMMLAPMVAAPGLAAADPATRPVDYQQITDVVIARGLSQRGVPFSWAGGGISGPTRG
TGTGINTVGFDASGLIQYAYAGAGLKLPRSSGQMYKVGQKVLPQQARKGDLIFYGPEGTQSVALYLGKGQ
MLEVGDVVQVSPVRTNGMTPYLVRVLGTQPTPVQQAPVQPAPVQQAPVQQAPVQQAPVQQAPVQQAPVQQ
APVQQAPVQPPPFGTARSR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1566c--100% (230)Possible inv protein
M. tuberculosis H37RvRv1477-6e-4055.73% (131) invasion protein
M. tuberculosis H37RvRv1478-6e-3949.08% (163) invasion protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1593c-1e-130100.00% (230) inv protein
M. gilvum PYR-GCKMflv_3253-3e-4449.04% (208) NLP/P60 protein
M. leprae Br4923MLBr_01214-3e-7966.82% (220) putative secreted p60-family protein
M. abscessus ATCC 19977MAB_2474-9e-4251.96% (179) hypothetical protein MAB_2474
M. marinum MMMAR_2381-1e-9778.04% (214) inv protein
M. avium 104MAV_3208-4e-9173.33% (225) NlpC/P60 family protein
M. smegmatis MC2 155MSMEG_3477-3e-4749.76% (211) inv protein
M. thermoresistible (build 8)TH_0420-2e-4556.07% (173) Possible inv protein
M. ulcerans Agy99MUL_1557-8e-9878.04% (214) inv protein
M. vanbaalenii PYR-1Mvan_2970-1e-4551.46% (206) NLP/P60 protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv1566c|M.tuberculosis_H37Rv        MKRSMKSGSFAIGLAMMLAPMV----AAPGLAAADPATRPVDYQQITDVV
Mb1593c|M.bovis_AF2122/97           MKRSMKSGSFAIGLAMMLAPMV----AAPGLAAADPATRPVDYQQITDVV
MLBr_01214|M.leprae_Br4923          MNRIY---TFVTGLAMLVTSIL----TCS-LAYADSGTRTADYQQTIDTV
MMAR_2381|M.marinum_M               MKRIY---AFAIGLVMMAAPMA----AAPGIAAADPSVRPVDYQQATDVV
MUL_1557|M.ulcerans_Agy99           MKRIY---AFAIGLVMMAAPMA----AAPGIAAADPSVRPVDYQQATDVV
MAV_3208|M.avium_104                MKRIY---AFAIGLALLGAPAAP--MVVPAVATADPGVRAMDYQQATDVV
Mflv_3253|M.gilvum_PYR-GCK          MRRLY---VFVIALALVLATPGVAVLATPGVATALP-GRSATNQKAVEAV
Mvan_2970|M.vanbaalenii_PYR-1       MRRLL---VFVIGLALLLATP--------GLATAQP-ARSATNQKAVEAV
MSMEG_3477|M.smegmatis_MC2_155      MRRAY---AVLVSLAVSTAVLLG----IPGIAAAAPYDRPAGNQRFVEIV
TH_0420|M.thermoresistible__bu      MRRVF---ALVISLAVLVATP--------AVAVAYP-SYPTRNHQAVKVV
MAB_2474|M.abscessus_ATCC_1997      MKSTY---AVLLGIALLLVTP--------GLASADVPRSPVDRQQAINAV
                                    *.       .  .:.:  .           :* *     .   ::  . *

Rv1566c|M.tuberculosis_H37Rv        IARGLSQRGVPFSWAGGGISGPTRGT------------------------
Mb1593c|M.bovis_AF2122/97           IARGLSQRGVPFSWAGGGISGPTRGT------------------------
MLBr_01214|M.leprae_Br4923          VQRALAQRGVPFSWAGGGVSGPTRGT------------------------
MMAR_2381|M.marinum_M               VARGLSQRGVPFSWAGGGITGPSRGK------------------------
MUL_1557|M.ulcerans_Agy99           VARGLSQRGVPFSWAGGGITGPSRGK------------------------
MAV_3208|M.avium_104                IARGLSQRGVPFSWAGGGINGPTRGT------------------------
Mflv_3253|M.gilvum_PYR-GCK          IARALSQRGVPFAYGGGGASGPSKGTVALPEAAPAVPDQA----EIDAQA
Mvan_2970|M.vanbaalenii_PYR-1       IARALSQRGVPFAYGGGGASGPSKGTVAVPEAEPALPDQA----EVDAQS
MSMEG_3477|M.smegmatis_MC2_155      IARALSQRGVPFTYGGGDVNGPTRGVPREIPPAAAVPTGAYPGLAPAATP
TH_0420|M.thermoresistible__bu      LERALSQQGVPFSYGGGDASGPTRGS------------------GTAANA
MAB_2474|M.abscessus_ATCC_1997      IARGLSQRGVPFTYGGGNTDGPTTST--------------------DTAP
                                    : *.*:*:****::.**.  **: .                         

Rv1566c|M.tuberculosis_H37Rv        ------------------------------GTGINTVGFDASGLIQYAYA
Mb1593c|M.bovis_AF2122/97           ------------------------------GTGINTVGFDASGLIQYAYA
MLBr_01214|M.leprae_Br4923          ------------------------------GTGSNTVGFDASGLIQYAYA
MMAR_2381|M.marinum_M               ------------------------------GTGIYTVGFDASGLIQYAYA
MUL_1557|M.ulcerans_Agy99           ------------------------------GTGIYTVGFDASGLIQYAYA
MAV_3208|M.avium_104                ------------------------------GTGANTVGFDASGLMQYAYA
Mflv_3253|M.gilvum_PYR-GCK          LTESPGLNLPGVTPNVAVPTLPAP-----PAPRVEVVGFDASGLMVYAFS
Mvan_2970|M.vanbaalenii_PYR-1       LDLAPGLNVPSVTPNVAAP-IPAPTPA--PAPRIEVVGFDASGLMVYAYA
MSMEG_3477|M.smegmatis_MC2_155      EALTPGLNTPAVTPGLSAPAITPGLVAPVAAPAPDVVGFDASGLIVYAFA
TH_0420|M.thermoresistible__bu      IGLDPAGRVVGLDP------------------AQNIVGFDASGLMVYAFA
MAB_2474|M.abscessus_ATCC_1997      AAPEANTSLLGLIPAPVA------------APTPKVPGFDASGLMVYSYA
                                                                         *******: *:::

Rv1566c|M.tuberculosis_H37Rv        GAGLKLPRSSGQMYKVGQKVLPQQARKGDLIFYGPEGTQSVALYLGKGQM
Mb1593c|M.bovis_AF2122/97           GAGLKLPRSSGQMYKVGQKVLPQQARKGDLIFYGPEGTQSVALYLGKGQM
MLBr_01214|M.leprae_Br4923          GAGLKLPRSSGEMYKVGQKVLPRHARRGDLIFYGPEGTESVTLYLGDEKM
MMAR_2381|M.marinum_M               GAGIKLPRSSGEMYKVGQKVLPQQARKADLLFYGPEGTQSVAMYLGNGQM
MUL_1557|M.ulcerans_Agy99           GAGIKLPRSSGEMYKVGQKVLPQQARKADLLFYGPEGTQSVAMYLGNGQM
MAV_3208|M.avium_104                GAGIKLPRSSGAMYRVGQKILPQQARKGDLIFYGPEGTQSVAMYLGNNQM
Mflv_3253|M.gilvum_PYR-GCK          GVGVKLPRSSGEMYKVGQKVAPALAMPGDLIFYGPEGTQSVALFIGNGQM
Mvan_2970|M.vanbaalenii_PYR-1       GVGVKLPRSSGEMYKVGQKVLPAQALPGDLIFYGPEGTQSVALFIGNGQM
MSMEG_3477|M.smegmatis_MC2_155      GAGVKMPRSSGEQYKVGQKVLPSQALPGDLIFYGPEGTQSVALFVGNGQM
TH_0420|M.thermoresistible__bu      GVGIKLPRSSGEQYKVGYKVTPDQALPGDLIFYGPEGTQSVALFLGNGQM
MAB_2474|M.abscessus_ATCC_1997      AAGIKLPRRSGDQYNVGRKILPAQALPGDLIFYGPNGSQSVTMFLGNNLM
                                    ..*:*:** **  *.** *: *  *  .**:****:*::**::::*.  *

Rv1566c|M.tuberculosis_H37Rv        LEVGD-VVQVSPVRTNGMTPYLVRVLG-----------------------
Mb1593c|M.bovis_AF2122/97           LEVGD-VVQVSPVRTNGMTPYLVRVLG-----------------------
MLBr_01214|M.leprae_Br4923          VEVGE-VVQVSPVRSNGMAPYLVRVLG-----------------------
MMAR_2381|M.marinum_M               LEVGD-VVQVSPVRTTDMMPYLVRIIG------------------ASQAP
MUL_1557|M.ulcerans_Agy99           LEVGD-VVQVSPVRTTDMMPYLVRIIG------------------ASQAP
MAV_3208|M.avium_104                LEVGD-VVQVSPVRTAGMAPYMVRVLGTTAPTQQVPQQAPLQQTPAQQAP
Mflv_3253|M.gilvum_PYR-GCK          VETTDTGVAVSPVRTNGMSPYLVRIIA-----------------------
Mvan_2970|M.vanbaalenii_PYR-1       VETTDAGVAVSSVRTKDMTPYLVRIIA-----------------------
MSMEG_3477|M.smegmatis_MC2_155      VETTDSGVQVSPVRTENMTPYLVRIIA-----------------------
TH_0420|M.thermoresistible__bu      IEATDPVVRVSPVRFDNMAPYLSRIIP-----------------------
MAB_2474|M.abscessus_ATCC_1997      LEASEPAVQVSQVRFNDMAPYLVRVIE-----------------------
                                    :*. :  * ** **  .* **: *::                        

Rv1566c|M.tuberculosis_H37Rv        ------------------------------TQPTPVQQAPVQPAP-----
Mb1593c|M.bovis_AF2122/97           ------------------------------TQPTPVQQAPVQPAP-----
MLBr_01214|M.leprae_Br4923          ------------------------------TQPTSVPQAPLQQVP-----
MMAR_2381|M.marinum_M               LQQTP-----LPQTP-----LRQAPLQQVPTQQVPTQQAPLQQAPAQQLP
MUL_1557|M.ulcerans_Agy99           LQQTP-----LPQTP-----LRQAPLQQVPTQQVPTQQAPLQQAPAQQLP
MAV_3208|M.avium_104                LQQTPGQQAPLQQTPGQQLPTQQAPLQQVPGQQVPAQQVPAQQVPGQQLP
Mflv_3253|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2970|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3477|M.smegmatis_MC2_155      --------------------------------------------------
TH_0420|M.thermoresistible__bu      --------------------------------------------------
MAB_2474|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Rv1566c|M.tuberculosis_H37Rv        ----VQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQPPPFGTARS
Mb1593c|M.bovis_AF2122/97           ----VQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQPPPFGTARS
MLBr_01214|M.leprae_Br4923          ----TLPAP-----------QQTPTHRAPLQHMPLQ-VPVRPVPVSTAR-
MMAR_2381|M.marinum_M               TQQAPLQAPTRQAPTQQVPLQQLPTQQSPVQQAPTQLVPLQPAPATTAR-
MUL_1557|M.ulcerans_Agy99           TQQAPLQAPTRQAPTQQVPLQQLPTQQSPVQQAPTQLVPLQPAPATTAR-
MAV_3208|M.avium_104                TQQAPQQAPLQLAPTQQAPLQQLPTQQSPLQQLPVQQSPLQPAGAGLTR-
Mflv_3253|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2970|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3477|M.smegmatis_MC2_155      --------------------------------------------------
TH_0420|M.thermoresistible__bu      --------------------------------------------------
MAB_2474|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Rv1566c|M.tuberculosis_H37Rv        R
Mb1593c|M.bovis_AF2122/97           R
MLBr_01214|M.leprae_Br4923          -
MMAR_2381|M.marinum_M               -
MUL_1557|M.ulcerans_Agy99           -
MAV_3208|M.avium_104                -
Mflv_3253|M.gilvum_PYR-GCK          -
Mvan_2970|M.vanbaalenii_PYR-1       -
MSMEG_3477|M.smegmatis_MC2_155      -
TH_0420|M.thermoresistible__bu      -
MAB_2474|M.abscessus_ATCC_1997      -