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KRSMKSGSFAIGLAMMLAPMVAAPGLAAADPATRPVDYQQITDVVIARGLSQRGVPFSWAGGGISGPTRG TGTGINTVGFDASGLIQYAYAGAGLKLPRSSGQMYKVGQKVLPQQARKGDLIFYGPEGTQSVALYLGKGQ MLEVGDVVQVSPVRTNGMTPYLVRVLGTQPTPVQQAPVQPAPVQQAPVQQAPVQQAPVQQAPVQQAPVQQ APVQQAPVQPPPFGTARSR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1566c | - | - | 100% (230) | Possible inv protein |
M. tuberculosis H37Rv | Rv1477 | - | 6e-40 | 55.73% (131) | invasion protein |
M. tuberculosis H37Rv | Rv1478 | - | 6e-39 | 49.08% (163) | invasion protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1593c | - | 1e-130 | 100.00% (230) | inv protein |
M. gilvum PYR-GCK | Mflv_3253 | - | 3e-44 | 49.04% (208) | NLP/P60 protein |
M. leprae Br4923 | MLBr_01214 | - | 3e-79 | 66.82% (220) | putative secreted p60-family protein |
M. abscessus ATCC 19977 | MAB_2474 | - | 9e-42 | 51.96% (179) | hypothetical protein MAB_2474 |
M. marinum M | MMAR_2381 | - | 1e-97 | 78.04% (214) | inv protein |
M. avium 104 | MAV_3208 | - | 4e-91 | 73.33% (225) | NlpC/P60 family protein |
M. smegmatis MC2 155 | MSMEG_3477 | - | 3e-47 | 49.76% (211) | inv protein |
M. thermoresistible (build 8) | TH_0420 | - | 2e-45 | 56.07% (173) | Possible inv protein |
M. ulcerans Agy99 | MUL_1557 | - | 8e-98 | 78.04% (214) | inv protein |
M. vanbaalenii PYR-1 | Mvan_2970 | - | 1e-45 | 51.46% (206) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv1566c|M.tuberculosis_H37Rv MKRSMKSGSFAIGLAMMLAPMV----AAPGLAAADPATRPVDYQQITDVV Mb1593c|M.bovis_AF2122/97 MKRSMKSGSFAIGLAMMLAPMV----AAPGLAAADPATRPVDYQQITDVV MLBr_01214|M.leprae_Br4923 MNRIY---TFVTGLAMLVTSIL----TCS-LAYADSGTRTADYQQTIDTV MMAR_2381|M.marinum_M MKRIY---AFAIGLVMMAAPMA----AAPGIAAADPSVRPVDYQQATDVV MUL_1557|M.ulcerans_Agy99 MKRIY---AFAIGLVMMAAPMA----AAPGIAAADPSVRPVDYQQATDVV MAV_3208|M.avium_104 MKRIY---AFAIGLALLGAPAAP--MVVPAVATADPGVRAMDYQQATDVV Mflv_3253|M.gilvum_PYR-GCK MRRLY---VFVIALALVLATPGVAVLATPGVATALP-GRSATNQKAVEAV Mvan_2970|M.vanbaalenii_PYR-1 MRRLL---VFVIGLALLLATP--------GLATAQP-ARSATNQKAVEAV MSMEG_3477|M.smegmatis_MC2_155 MRRAY---AVLVSLAVSTAVLLG----IPGIAAAAPYDRPAGNQRFVEIV TH_0420|M.thermoresistible__bu MRRVF---ALVISLAVLVATP--------AVAVAYP-SYPTRNHQAVKVV MAB_2474|M.abscessus_ATCC_1997 MKSTY---AVLLGIALLLVTP--------GLASADVPRSPVDRQQAINAV *. . .:.: . :* * . :: . * Rv1566c|M.tuberculosis_H37Rv IARGLSQRGVPFSWAGGGISGPTRGT------------------------ Mb1593c|M.bovis_AF2122/97 IARGLSQRGVPFSWAGGGISGPTRGT------------------------ MLBr_01214|M.leprae_Br4923 VQRALAQRGVPFSWAGGGVSGPTRGT------------------------ MMAR_2381|M.marinum_M VARGLSQRGVPFSWAGGGITGPSRGK------------------------ MUL_1557|M.ulcerans_Agy99 VARGLSQRGVPFSWAGGGITGPSRGK------------------------ MAV_3208|M.avium_104 IARGLSQRGVPFSWAGGGINGPTRGT------------------------ Mflv_3253|M.gilvum_PYR-GCK IARALSQRGVPFAYGGGGASGPSKGTVALPEAAPAVPDQA----EIDAQA Mvan_2970|M.vanbaalenii_PYR-1 IARALSQRGVPFAYGGGGASGPSKGTVAVPEAEPALPDQA----EVDAQS MSMEG_3477|M.smegmatis_MC2_155 IARALSQRGVPFTYGGGDVNGPTRGVPREIPPAAAVPTGAYPGLAPAATP TH_0420|M.thermoresistible__bu LERALSQQGVPFSYGGGDASGPTRGS------------------GTAANA MAB_2474|M.abscessus_ATCC_1997 IARGLSQRGVPFTYGGGNTDGPTTST--------------------DTAP : *.*:*:****::.**. **: . Rv1566c|M.tuberculosis_H37Rv ------------------------------GTGINTVGFDASGLIQYAYA Mb1593c|M.bovis_AF2122/97 ------------------------------GTGINTVGFDASGLIQYAYA MLBr_01214|M.leprae_Br4923 ------------------------------GTGSNTVGFDASGLIQYAYA MMAR_2381|M.marinum_M ------------------------------GTGIYTVGFDASGLIQYAYA MUL_1557|M.ulcerans_Agy99 ------------------------------GTGIYTVGFDASGLIQYAYA MAV_3208|M.avium_104 ------------------------------GTGANTVGFDASGLMQYAYA Mflv_3253|M.gilvum_PYR-GCK LTESPGLNLPGVTPNVAVPTLPAP-----PAPRVEVVGFDASGLMVYAFS Mvan_2970|M.vanbaalenii_PYR-1 LDLAPGLNVPSVTPNVAAP-IPAPTPA--PAPRIEVVGFDASGLMVYAYA MSMEG_3477|M.smegmatis_MC2_155 EALTPGLNTPAVTPGLSAPAITPGLVAPVAAPAPDVVGFDASGLIVYAFA TH_0420|M.thermoresistible__bu IGLDPAGRVVGLDP------------------AQNIVGFDASGLMVYAFA MAB_2474|M.abscessus_ATCC_1997 AAPEANTSLLGLIPAPVA------------APTPKVPGFDASGLMVYSYA *******: *::: Rv1566c|M.tuberculosis_H37Rv GAGLKLPRSSGQMYKVGQKVLPQQARKGDLIFYGPEGTQSVALYLGKGQM Mb1593c|M.bovis_AF2122/97 GAGLKLPRSSGQMYKVGQKVLPQQARKGDLIFYGPEGTQSVALYLGKGQM MLBr_01214|M.leprae_Br4923 GAGLKLPRSSGEMYKVGQKVLPRHARRGDLIFYGPEGTESVTLYLGDEKM MMAR_2381|M.marinum_M GAGIKLPRSSGEMYKVGQKVLPQQARKADLLFYGPEGTQSVAMYLGNGQM MUL_1557|M.ulcerans_Agy99 GAGIKLPRSSGEMYKVGQKVLPQQARKADLLFYGPEGTQSVAMYLGNGQM MAV_3208|M.avium_104 GAGIKLPRSSGAMYRVGQKILPQQARKGDLIFYGPEGTQSVAMYLGNNQM Mflv_3253|M.gilvum_PYR-GCK GVGVKLPRSSGEMYKVGQKVAPALAMPGDLIFYGPEGTQSVALFIGNGQM Mvan_2970|M.vanbaalenii_PYR-1 GVGVKLPRSSGEMYKVGQKVLPAQALPGDLIFYGPEGTQSVALFIGNGQM MSMEG_3477|M.smegmatis_MC2_155 GAGVKMPRSSGEQYKVGQKVLPSQALPGDLIFYGPEGTQSVALFVGNGQM TH_0420|M.thermoresistible__bu GVGIKLPRSSGEQYKVGYKVTPDQALPGDLIFYGPEGTQSVALFLGNGQM MAB_2474|M.abscessus_ATCC_1997 AAGIKLPRRSGDQYNVGRKILPAQALPGDLIFYGPNGSQSVTMFLGNNLM ..*:*:** ** *.** *: * * .**:****:*::**::::*. * Rv1566c|M.tuberculosis_H37Rv LEVGD-VVQVSPVRTNGMTPYLVRVLG----------------------- Mb1593c|M.bovis_AF2122/97 LEVGD-VVQVSPVRTNGMTPYLVRVLG----------------------- MLBr_01214|M.leprae_Br4923 VEVGE-VVQVSPVRSNGMAPYLVRVLG----------------------- MMAR_2381|M.marinum_M LEVGD-VVQVSPVRTTDMMPYLVRIIG------------------ASQAP MUL_1557|M.ulcerans_Agy99 LEVGD-VVQVSPVRTTDMMPYLVRIIG------------------ASQAP MAV_3208|M.avium_104 LEVGD-VVQVSPVRTAGMAPYMVRVLGTTAPTQQVPQQAPLQQTPAQQAP Mflv_3253|M.gilvum_PYR-GCK VETTDTGVAVSPVRTNGMSPYLVRIIA----------------------- Mvan_2970|M.vanbaalenii_PYR-1 VETTDAGVAVSSVRTKDMTPYLVRIIA----------------------- MSMEG_3477|M.smegmatis_MC2_155 VETTDSGVQVSPVRTENMTPYLVRIIA----------------------- TH_0420|M.thermoresistible__bu IEATDPVVRVSPVRFDNMAPYLSRIIP----------------------- MAB_2474|M.abscessus_ATCC_1997 LEASEPAVQVSQVRFNDMAPYLVRVIE----------------------- :*. : * ** ** .* **: *:: Rv1566c|M.tuberculosis_H37Rv ------------------------------TQPTPVQQAPVQPAP----- Mb1593c|M.bovis_AF2122/97 ------------------------------TQPTPVQQAPVQPAP----- MLBr_01214|M.leprae_Br4923 ------------------------------TQPTSVPQAPLQQVP----- MMAR_2381|M.marinum_M LQQTP-----LPQTP-----LRQAPLQQVPTQQVPTQQAPLQQAPAQQLP MUL_1557|M.ulcerans_Agy99 LQQTP-----LPQTP-----LRQAPLQQVPTQQVPTQQAPLQQAPAQQLP MAV_3208|M.avium_104 LQQTPGQQAPLQQTPGQQLPTQQAPLQQVPGQQVPAQQVPAQQVPGQQLP Mflv_3253|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2970|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3477|M.smegmatis_MC2_155 -------------------------------------------------- TH_0420|M.thermoresistible__bu -------------------------------------------------- MAB_2474|M.abscessus_ATCC_1997 -------------------------------------------------- Rv1566c|M.tuberculosis_H37Rv ----VQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQPPPFGTARS Mb1593c|M.bovis_AF2122/97 ----VQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQQAPVQPPPFGTARS MLBr_01214|M.leprae_Br4923 ----TLPAP-----------QQTPTHRAPLQHMPLQ-VPVRPVPVSTAR- MMAR_2381|M.marinum_M TQQAPLQAPTRQAPTQQVPLQQLPTQQSPVQQAPTQLVPLQPAPATTAR- MUL_1557|M.ulcerans_Agy99 TQQAPLQAPTRQAPTQQVPLQQLPTQQSPVQQAPTQLVPLQPAPATTAR- MAV_3208|M.avium_104 TQQAPQQAPLQLAPTQQAPLQQLPTQQSPLQQLPVQQSPLQPAGAGLTR- Mflv_3253|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2970|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3477|M.smegmatis_MC2_155 -------------------------------------------------- TH_0420|M.thermoresistible__bu -------------------------------------------------- MAB_2474|M.abscessus_ATCC_1997 -------------------------------------------------- Rv1566c|M.tuberculosis_H37Rv R Mb1593c|M.bovis_AF2122/97 R MLBr_01214|M.leprae_Br4923 - MMAR_2381|M.marinum_M - MUL_1557|M.ulcerans_Agy99 - MAV_3208|M.avium_104 - Mflv_3253|M.gilvum_PYR-GCK - Mvan_2970|M.vanbaalenii_PYR-1 - MSMEG_3477|M.smegmatis_MC2_155 - TH_0420|M.thermoresistible__bu - MAB_2474|M.abscessus_ATCC_1997 -