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GLHVRSKGAAIASTDRCDPAILVAGRVRRLPGVIAIVVLLFLACAPVASAQPAAGPWDPLLPKIPSAGAP GDPVAIANASLQATAMATQTAMNMGRSFLSSLGIVSPAADPSTSVRGNRVNGAQAIEYVIRRAGTQIGVP YSWGGGSLTGPSRGVDQGAGTVGFDCSGLTRFAFAGVGVLLPRWSGDQYDAGRKVPPSQAKRGDLLFWGP GGSQHEAIYLGGGQMIEAQQTGVPIKVSPVRTGGMTPYVVRIIES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2843 | - | - | 100% (256) | NLP/P60 protein |
| M. gilvum PYR-GCK | Mflv_0902 | - | e-133 | 91.67% (252) | NLP/P60 protein |
| M. gilvum PYR-GCK | Mflv_2872 | - | 3e-86 | 93.29% (164) | NLP/P60 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1514 | - | 1e-79 | 63.09% (233) | invasion protein |
| M. tuberculosis H37Rv | Rv1478 | - | 1e-79 | 63.09% (233) | invasion protein |
| M. leprae Br4923 | MLBr_01811 | - | 2e-74 | 59.92% (237) | putative exported p60 protein homologue |
| M. abscessus ATCC 19977 | MAB_2728c | - | 7e-57 | 51.61% (217) | invasion protein Inv1 |
| M. marinum M | MMAR_2285 | iipB | 2e-76 | 62.83% (226) | invasion and intracellular persistence protein, IipB |
| M. avium 104 | MAV_3300 | - | 3e-74 | 60.00% (230) | invasin 1 |
| M. smegmatis MC2 155 | MSMEG_3146 | - | 1e-81 | 65.22% (230) | invasin 1 |
| M. thermoresistible (build 8) | TH_4058 | - | 4e-79 | 62.83% (226) | PUTATIVE NLP/P60 protein |
| M. ulcerans Agy99 | MUL_1487 | inv2 | 3e-76 | 62.39% (226) | invasion protein Inv2 |
| M. vanbaalenii PYR-1 | Mvan_3652 | - | 1e-136 | 92.61% (257) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2843|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3652|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2285|M.marinum_M --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
MAV_3300|M.avium_104 --------------------------------------------------
MSMEG_3146|M.smegmatis_MC2_155 --------------------------------------------------
TH_4058|M.thermoresistible__bu --------------------------------------------------
MAB_2728c|M.abscessus_ATCC_199 MKRTVNDRFAVRGKRTVATALMVPPLLVAGLMMFPTTVAVTSAEPNDMAS
Mflv_2843|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3652|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2285|M.marinum_M --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
MAV_3300|M.avium_104 --------------------------------------------------
MSMEG_3146|M.smegmatis_MC2_155 --------------------------------------------------
TH_4058|M.thermoresistible__bu --------------------------------------------------
MAB_2728c|M.abscessus_ATCC_199 LITQLADTNQQIEQLTADVQTQQESINKGLVDLQAARDNAASAAAQVAEG
Mflv_2843|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3652|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2285|M.marinum_M --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
MAV_3300|M.avium_104 --------------------------------------------------
MSMEG_3146|M.smegmatis_MC2_155 --------------------------------------------------
TH_4058|M.thermoresistible__bu --------------------------------------------------
MAB_2728c|M.abscessus_ATCC_199 QRAVDAANGAIEEAQGKFDRMAAATYMAGPSTSYLTATNPDDVVRLASVT
Mflv_2843|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3652|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2285|M.marinum_M --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
MAV_3300|M.avium_104 --------------------------------------------------
MSMEG_3146|M.smegmatis_MC2_155 --------------------------------------------------
TH_4058|M.thermoresistible__bu --------------------------------------------------
MAB_2728c|M.abscessus_ATCC_199 KSVEASSQTVMDNLRRARTEQVNKQSQARAIQEKADQAAADAQQQQDDLV
Mflv_2843|M.gilvum_PYR-GCK ----------------MGLHVRSKGAAIASTDRCDPAILVAGR-VRRLPG
Mvan_3652|M.vanbaalenii_PYR-1 ----------------MESHVRSKGAPTARADRCDPTILVAAQAVRRLSG
MMAR_2285|M.marinum_M -------------MSSYRGPMRYK-----------------RFRLLGLAW
MUL_1487|M.ulcerans_Agy99 --------------------MRYK-----------------RFRLLGLAW
Mb1514|M.bovis_AF2122/97 --------------------MRHT-----------------RFHPIKLAW
Rv1478|M.tuberculosis_H37Rv --------------------MRHT-----------------RFHPIKLAW
MLBr_01811|M.leprae_Br4923 --------------------MRHK-----------------NFRLINLAG
MAV_3300|M.avium_104 --------------------MRRN-----------------RFRLIVFAW
MSMEG_3146|M.smegmatis_MC2_155 -------------------------------------------MVLRALI
TH_4058|M.thermoresistible__bu ----------------VVILLRSK-----------------TFRLLRPLI
MAB_2728c|M.abscessus_ATCC_199 SAMKDVQKKLEAQRGVAADLTAKKKSAEAQLAAARGPAYAASTATARVIN
Mflv_2843|M.gilvum_PYR-GCK VIAIVVLLFLACAPVASAQPAAGPWDPLLPKIPSAGAPGDPVAIANASLQ
Mvan_3652|M.vanbaalenii_PYR-1 VIAIVVLLFLACAPVASAQPAAGPWDPLLPKVASAGAPGDPVAIANASLQ
MMAR_2285|M.marinum_M ITLAVAALLVVVSAP--ADADPGGWDPTLPATASAGAPGDALAMANASLQ
MUL_1487|M.ulcerans_Agy99 ITLAVAALMVVVSAP--ADADPGGWDPTLPATASAGAPGDALAMANASLQ
Mb1514|M.bovis_AF2122/97 ITAVVAGLMVGVATP--ADAEPGQWDPTLPALVSAGAPGDPLAVANASLQ
Rv1478|M.tuberculosis_H37Rv ITAVVAGLMVGVATP--ADAEPGQWDPTLPALVSAGAPGDPLAVANASLQ
MLBr_01811|M.leprae_Br4923 LTAMVAGLIIVVTIP--ATADPGQWDPTLPAAVSAGAPGDPLAVANASLQ
MAV_3300|M.avium_104 ITAMVTGLMFSVAPTPAALADPGEWDPTLPAQISAGAPGDPLAVANASLQ
MSMEG_3146|M.smegmatis_MC2_155 AVVAVAFAAVGLVAPAGAAPEDGQWDPTLPKLISAGAPGDPLAIANASLE
TH_4058|M.thermoresistible__bu PAILGLGVLIAAAGPATAAPDDGQWDPTLPKLISAGAPGDPLAIANASLA
MAB_2728c|M.abscessus_ATCC_199 PSAAIAGNGNEWTEGPAPVSSGGQWDTTLPMIASANVPTDPTQTINMVLG
. . * **. ** **..* *. * *
Mflv_2843|M.gilvum_PYR-GCK ATAMATQTAMNMGRSFLSSLGIVSPA---ADPSTSVRG------NRVNGA
Mvan_3652|M.vanbaalenii_PYR-1 ATAMATQTAMSMGRNFLSSLGLVSPA---ADPSTSVRG------NRVNGA
MMAR_2285|M.marinum_M ATAQATQTTLDLGRQFLGGLGINLGG--SPAPSAANTG--ANRIPRVYGQ
MUL_1487|M.ulcerans_Agy99 ATAQATQTTLDLGRQFLGGLGINLGG--SPAPSAANTG--ANRIPRVYGR
Mb1514|M.bovis_AF2122/97 ATAQATQTTLDLGRQFLGGLGINLGGPAASAPSAATTG--ASRIPRANAR
Rv1478|M.tuberculosis_H37Rv ATAQATQTTLDLGRQFLGGLGINLGGPAASAPSAATTG--ASRIPRANAR
MLBr_01811|M.leprae_Br4923 VTAQATQTTLDLGKQFLGRLGINFGG-DPSNAATTSSNP-GGRIPRVYGG
MAV_3300|M.avium_104 ATAQATQTTLNLGKQFLGGLGINLGGNDAPAAAATPSNP-GGKIPRVYGR
MSMEG_3146|M.smegmatis_MC2_155 ATAQATQVTMGLGRKFLASLGLVEDT---PAAAGVAPG-------RVRGP
TH_4058|M.thermoresistible__bu ATAQATQVTMDLGRKFLASIGLGGSQ---PVSS-VAPG-------RVRGP
MAB_2728c|M.abscessus_ATCC_199 IGNTAANVGQSA---VCGVIGIFCPK---AAPAAAASGEGGEYLPKVYGR
*::. . . . :*: . .: . :. .
Mflv_2843|M.gilvum_PYR-GCK QAIEYVIRRAGTQIGVPYSWGGGSLTGPSRGVDQGAGTVGFDCSGLTRFA
Mvan_3652|M.vanbaalenii_PYR-1 QAIEYVIRRAGTQIGVPYSWGGGSLTGPSRGVDQGAGTVGFDCSGLTRFA
MMAR_2285|M.marinum_M QALEYVIRRGGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLMRYA
MUL_1487|M.ulcerans_Agy99 QALEYVIRRGGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLMRYA
Mb1514|M.bovis_AF2122/97 QAVEYVIRRAGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYA
Rv1478|M.tuberculosis_H37Rv QAVEYVIRRAGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYA
MLBr_01811|M.leprae_Br4923 QAIEYVIKRGGAQIGVPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYA
MAV_3300|M.avium_104 QAIEYVIKRMGSQMGVPYSWGGGSLDGPSKGVGDGANITGFDCSGLMRYG
MSMEG_3146|M.smegmatis_MC2_155 QAIEYVIRRGGTQMGVPYSWGGGKPNGPSRGIDSGANTVGFDCSGFTQFS
TH_4058|M.thermoresistible__bu QAIEYVIRRGASQLGVPYSWGGGKPSGPSTGVGSGANTVGFDCSGFTQFA
MAB_2728c|M.abscessus_ATCC_199 ENVERVIARAGSAMGTPYSWGGGSYNGPTRGIDSGAGTVGYDCSGLMMYG
: :* ** * .: :*.*******. **: *:..**. .*:****: :.
Mflv_2843|M.gilvum_PYR-GCK FAGVGVLLPRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGG
Mvan_3652|M.vanbaalenii_PYR-1 FAGVGVLLPRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGG
MMAR_2285|M.marinum_M FAGVGVLIPRYSGDQYNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNG
MUL_1487|M.ulcerans_Agy99 FAGVGVLIPRYSGDQYNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNG
Mb1514|M.bovis_AF2122/97 FAGVGVLIPRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNG
Rv1478|M.tuberculosis_H37Rv FAGVGVLIPRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNG
MLBr_01811|M.leprae_Br4923 FAGVGVLIPRFSGDQYNAGRHLTPDQAKRGDLIFYGPGGGQHVTMYLGNG
MAV_3300|M.avium_104 FAGVGVLIPRFSGDQYNAGRHIPQDQARRGDLIFYGPGGSQHVTMYLGNG
MSMEG_3146|M.smegmatis_MC2_155 FAGVGVLIPKYSGDQYNTGRKVPVNQAKRGDLLFWGPGGSQHVALYLGGG
TH_4058|M.thermoresistible__bu FAGVGVLIPKYSGDQYNTGRKVPVSQAKRGDLLFWGPGGSQHVALYLGNG
MAB_2728c|M.abscessus_ATCC_199 FAAVGIRLRHYTGYQYNSGRKVPSAQMKRGDMIFYGPNASQHVALYLGNG
**.**: : :::* **::**::. : :***::*:**...** ::***.*
Mflv_2843|M.gilvum_PYR-GCK QMIEAQQTGVPIKVSPVRTGGMTPYVVRIIES
Mvan_3652|M.vanbaalenii_PYR-1 QMLEAQQTGVPIKISPVRTSGMTPYVVRIIES
MMAR_2285|M.marinum_M QMLEASGSAGKVTVSPVRKAGMTPFVTRIIEY
MUL_1487|M.ulcerans_Agy99 QMLEASGSAGKVTVSPVRKAGMTPFVTRIIEY
Mb1514|M.bovis_AF2122/97 QMLEASGSAGKVTVSPVRKAGMTPFVTRIIEY
Rv1478|M.tuberculosis_H37Rv QMLEASGSAGKVTVSPVRKAGMTPFVTRIIEY
MLBr_01811|M.leprae_Br4923 QMLEASSSVGKVTVSSVRKAGMTPFVTRIIES
MAV_3300|M.avium_104 QMLEASGSAGKVTVSPVRKPGMTPFLTRIIEY
MSMEG_3146|M.smegmatis_MC2_155 KMLEASGSAGKVTVSPVRMSGLQPYAARIIES
TH_4058|M.thermoresistible__bu QMLEASGSAGKVVAGPVRTAGLQPYAARIIET
MAB_2728c|M.abscessus_ATCC_199 QMLEAPNTGDVVKVSPVRTSGMTPYVTRMIEW
:*:** : : ..** *: *: .*:**