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RHKNFRLINLAGLTAMVAGLIIVVTIPATADPGQWDPTLPAAVSAGAPGDPLAVANASLQVTAQATQTTL DLGKQFLGRLGINFGGDPSNAATTSSNPGGRIPRVYGGQAIEYVIKRGGAQIGVPYSWGGGSLQGPSKGV GDGANITGFDCSGLMRYAFAGVGVLIPRFSGDQYNAGRHLTPDQAKRGDLIFYGPGGGQHVTMYLGNGQM LEASSSVGKVTVSSVRKAGMTPFVTRIIES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01811 | - | - | 100% (241) | putative exported p60 protein homologue |
| M. leprae Br4923 | MLBr_01812 | - | 1e-66 | 56.16% (219) | putative exported p60 protein homologue |
| M. leprae Br4923 | MLBr_01214 | - | 1e-34 | 50.38% (131) | putative secreted p60-family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1514 | - | 1e-106 | 77.08% (240) | invasion protein |
| M. gilvum PYR-GCK | Mflv_2843 | - | 5e-74 | 59.92% (237) | NLP/P60 protein |
| M. tuberculosis H37Rv | Rv1478 | - | 1e-106 | 77.08% (240) | invasion protein |
| M. abscessus ATCC 19977 | MAB_2727c | - | 6e-54 | 53.62% (207) | invasion protein Inv2 |
| M. marinum M | MMAR_2285 | iipB | 1e-108 | 79.25% (241) | invasion and intracellular persistence protein, IipB |
| M. avium 104 | MAV_3300 | - | 1e-109 | 81.07% (243) | invasin 1 |
| M. smegmatis MC2 155 | MSMEG_3146 | - | 7e-75 | 60.43% (235) | invasin 1 |
| M. thermoresistible (build 8) | TH_4058 | - | 5e-79 | 60.49% (243) | PUTATIVE NLP/P60 protein |
| M. ulcerans Agy99 | MUL_1487 | inv2 | 1e-108 | 79.25% (241) | invasion protein Inv2 |
| M. vanbaalenii PYR-1 | Mvan_3652 | - | 4e-74 | 60.09% (233) | NLP/P60 protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2843|M.gilvum_PYR-GCK MGLHVRSKGAAIASTDRCDPAILVAGR-VRRLPGVIAIVVLLFLACAPVA
Mvan_3652|M.vanbaalenii_PYR-1 MESHVRSKGAPTARADRCDPTILVAAQAVRRLSGVIAIVVLLFLACAPVA
MLBr_01811|M.leprae_Br4923 ------------MRHKNFR---------LINLAGLTAMVAGLIIVVTIP-
MAV_3300|M.avium_104 ------------MRRNRFR---------LIVFAWITAMVTGLMFSVAPTP
MMAR_2285|M.marinum_M -----MSSYRGPMRYKRFR---------LLGLAWITLAVAALLVVVSAP-
MUL_1487|M.ulcerans_Agy99 ------------MRYKRFR---------LLGLAWITLAVAALMVVVSAP-
Mb1514|M.bovis_AF2122/97 ------------MRHTRFH---------PIKLAWITAVVAGLMVGVATP-
Rv1478|M.tuberculosis_H37Rv ------------MRHTRFH---------PIKLAWITAVVAGLMVGVATP-
MSMEG_3146|M.smegmatis_MC2_155 ------------------M---------VLRALIAVVAVAFAAVGLVAPA
TH_4058|M.thermoresistible__bu --------VVILLRSKTFR---------LLRPLIPAILGLGVLIAAAGPA
MAB_2727c|M.abscessus_ATCC_199 --------------MQGLF---------LLRSAIAVTIAIALVLFMGVPR
.
Mflv_2843|M.gilvum_PYR-GCK SAQPAAGPWDP--------LLPKIPSAGAPGDPVAIANASLQAT-AMATQ
Mvan_3652|M.vanbaalenii_PYR-1 SAQPAAGPWDP--------LLPKVASAGAPGDPVAIANASLQAT-AMATQ
MLBr_01811|M.leprae_Br4923 -ATADPGQWDP--------TLPAAVSAGAPGDPLAVANASLQVT-AQATQ
MAV_3300|M.avium_104 AALADPGEWDP--------TLPAQISAGAPGDPLAVANASLQAT-AQATQ
MMAR_2285|M.marinum_M -ADADPGGWDP--------TLPATASAGAPGDALAMANASLQAT-AQATQ
MUL_1487|M.ulcerans_Agy99 -ADADPGGWDP--------TLPATASAGAPGDALAMANASLQAT-AQATQ
Mb1514|M.bovis_AF2122/97 -ADAEPGQWDP--------TLPALVSAGAPGDPLAVANASLQAT-AQATQ
Rv1478|M.tuberculosis_H37Rv -ADAEPGQWDP--------TLPALVSAGAPGDPLAVANASLQAT-AQATQ
MSMEG_3146|M.smegmatis_MC2_155 GAAPEDGQWDP--------TLPKLISAGAPGDPLAIANASLEAT-AQATQ
TH_4058|M.thermoresistible__bu TAAPDDGQWDP--------TLPKLISAGAPGDPLAIANASLAAT-AQATQ
MAB_2727c|M.abscessus_ATCC_199 -AAADDNPLGPNVGTAFLNALGLNPTGGQYDPTLPFAGPSQGADPAKIMN
* . . .* * :.* . .:..*..* . * :
Mflv_2843|M.gilvum_PYR-GCK TAMNMGRSFLSSLGI-------VSPAADPST-SVRGNRVNGAQAIEYVIR
Mvan_3652|M.vanbaalenii_PYR-1 TAMSMGRNFLSSLGL-------VSPAADPST-SVRGNRVNGAQAIEYVIR
MLBr_01811|M.leprae_Br4923 TTLDLGKQFLGRLGINFGG-DPSNAATTSSNPGGRIPRVYGGQAIEYVIK
MAV_3300|M.avium_104 TTLNLGKQFLGGLGINLGGNDAPAAAATPSNPGGKIPRVYGRQAIEYVIK
MMAR_2285|M.marinum_M TTLDLGRQFLGGLGINLGG--SPAPSAANTG-ANRIPRVYGQQALEYVIR
MUL_1487|M.ulcerans_Agy99 TTLDLGRQFLGGLGINLGG--SPAPSAANTG-ANRIPRVYGRQALEYVIR
Mb1514|M.bovis_AF2122/97 TTLDLGRQFLGGLGINLGGPAASAPSAATTG-ASRIPRANARQAVEYVIR
Rv1478|M.tuberculosis_H37Rv TTLDLGRQFLGGLGINLGGPAASAPSAATTG-ASRIPRANARQAVEYVIR
MSMEG_3146|M.smegmatis_MC2_155 VTMGLGRKFLASLGLV---------EDTPAAAGVAPGRVRGPQAIEYVIR
TH_4058|M.thermoresistible__bu VTMDLGRKFLASIGLG---------GSQPVSS-VAPGRVRGPQAIEYVIR
MAB_2727c|M.abscessus_ATCC_199 GVMGVGQTALGALGIG----------GNSASAGAGRPLVYGRAAVERVIQ
.:.:*: *. :*: . . *:* **:
Mflv_2843|M.gilvum_PYR-GCK RAGTQIGVPYSWGGGSLTGPSRGVDQGAGTVGFDCSGLTRFAFAGVGVLL
Mvan_3652|M.vanbaalenii_PYR-1 RAGTQIGVPYSWGGGSLTGPSRGVDQGAGTVGFDCSGLTRFAFAGVGVLL
MLBr_01811|M.leprae_Br4923 RGGAQIGVPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYAFAGVGVLI
MAV_3300|M.avium_104 RMGSQMGVPYSWGGGSLDGPSKGVGDGANITGFDCSGLMRYGFAGVGVLI
MMAR_2285|M.marinum_M RGGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLMRYAFAGVGVLI
MUL_1487|M.ulcerans_Agy99 RGGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLMRYAFAGVGVLI
Mb1514|M.bovis_AF2122/97 RAGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAFAGVGVLI
Rv1478|M.tuberculosis_H37Rv RAGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAFAGVGVLI
MSMEG_3146|M.smegmatis_MC2_155 RGGTQMGVPYSWGGGKPNGPSRGIDSGANTVGFDCSGFTQFSFAGVGVLI
TH_4058|M.thermoresistible__bu RGASQLGVPYSWGGGKPSGPSTGVGSGANTVGFDCSGFTQFAFAGVGVLI
MAB_2727c|M.abscessus_ATCC_199 RGGTQLGVPYSWGGGTVRGPSGGVDYDSGKVGYDCSGFTMFSYAAAGVKL
* .:*:*********. *** *:. .:. .*:****: :.:*..** :
Mflv_2843|M.gilvum_PYR-GCK PRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGGQMIEAQQT
Mvan_3652|M.vanbaalenii_PYR-1 PRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGGQMLEAQQT
MLBr_01811|M.leprae_Br4923 PRFSGDQYNAGRHLTPDQAKRGDLIFYGPGGGQHVTMYLGNGQMLEASSS
MAV_3300|M.avium_104 PRFSGDQYNAGRHIPQDQARRGDLIFYGPGGSQHVTMYLGNGQMLEASGS
MMAR_2285|M.marinum_M PRYSGDQYNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNGQMLEASGS
MUL_1487|M.ulcerans_Agy99 PRYSGDQYNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNGQMLEASGS
Mb1514|M.bovis_AF2122/97 PRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGS
Rv1478|M.tuberculosis_H37Rv PRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGS
MSMEG_3146|M.smegmatis_MC2_155 PKYSGDQYNTGRKVPVNQAKRGDLLFWGPGGSQHVALYLGGGKMLEASGS
TH_4058|M.thermoresistible__bu PKYSGDQYNTGRKVPVSQAKRGDLLFWGPGGSQHVALYLGNGQMLEASGS
MAB_2727c|M.abscessus_ATCC_199 PKYSGDQYNAGQKVPVAQAKRGDLLFYGPGGSQHVVIYLGNGQMLEASGS
*::*****::*:::. :*:****:*:****.** .:***.*:*:**. :
Mflv_2843|M.gilvum_PYR-GCK GVPIKVSPVRTGGMTPYVVRIIES
Mvan_3652|M.vanbaalenii_PYR-1 GVPIKISPVRTSGMTPYVVRIIES
MLBr_01811|M.leprae_Br4923 VGKVTVSSVRKAGMTPFVTRIIES
MAV_3300|M.avium_104 AGKVTVSPVRKPGMTPFLTRIIEY
MMAR_2285|M.marinum_M AGKVTVSPVRKAGMTPFVTRIIEY
MUL_1487|M.ulcerans_Agy99 AGKVTVSPVRKAGMTPFVTRIIEY
Mb1514|M.bovis_AF2122/97 AGKVTVSPVRKAGMTPFVTRIIEY
Rv1478|M.tuberculosis_H37Rv AGKVTVSPVRKAGMTPFVTRIIEY
MSMEG_3146|M.smegmatis_MC2_155 AGKVTVSPVRMSGLQPYAARIIES
TH_4058|M.thermoresistible__bu AGKVVAGPVRTAGLQPYAARIIET
MAB_2727c|M.abscessus_ATCC_199 AGKVTVSPVRTGGMTPYAVRIIAW
: ..** *: *: .***