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PGARRSTDWLSGHRNEAAVDRILDAAQELYTQRDSESIGMNEIARAAGCSRATLYRYFENREALRTAYVH REANRLGRAIMEQIDGIDEPRQRLTASITTTLRMVRGNPALASWFAVTRPPIAGELAEHSEVITALAAAF VGSLGPEEPAVVERRARWVVRVITSLLLFPGHDEADERAMIEEFVVPIVTPVSARG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1403 | - | - | 100% (197) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0009 | - | 3e-16 | 31.28% (179) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5275 | - | 2e-12 | 27.81% (187) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1805c | - | 2e-18 | 30.05% (183) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2228 | - | 5e-62 | 61.34% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 6e-78 | 75.00% (188) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02568 | - | 1e-08 | 29.37% (126) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1938c | - | 2e-22 | 31.91% (188) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4185 | - | 5e-78 | 75.13% (189) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_5040 | - | 8e-60 | 58.64% (191) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2228 | - | 8e-55 | 57.69% (182) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4487 | - | 3e-78 | 75.13% (189) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4466 | - | 7e-63 | 64.13% (184) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1805c|M.bovis_AF2122/97 -MPG----NDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDKLAREV
MAB_1938c|M.abscessus_ATCC_199 MSPY----ADWLHGSDRHTIAADRIVSVAAKQIARHGLDRLNLDAVAREA
MMAR_4185|M.marinum_M -MG----RTDWLAA-HRSEVAADRILDAAERLYTEHDPASIGMNEIARAA
MUL_4487|M.ulcerans_Agy99 -MG----RTDWLAA-HRSEVAADRILDAAERLYTEHDPASIGMNEIARAA
MAV_1403|M.avium_104 -MPGARRSTDWLSG-HRNEAAVDRILDAAQELYTQRDSESIGMNEIARAA
Rv1255c|M.tuberculosis_H37Rv -MAG----TDWLSA-RRTELAADRILDAAERLFTQRDPASIGMNEIAKAA
Mflv_2228|M.gilvum_PYR-GCK -MAG-----DWLAA-RRTEVAADRILDAAGELFAAQSAATVGMHEIAAAA
Mvan_4466|M.vanbaalenii_PYR-1 -MAG-----DWLAA-RRTEVAADRILDAAGELFAAQPAATVGMHEIASAA
MSMEG_5040|M.smegmatis_MC2_155 -MA------DWLAG-RRGEVAADLILDAADALFARKDAATVGMHEIAAAA
TH_2228|M.thermoresistible__bu -MTG-----NWLAD-RRTEVAAERILDAAHELFTRHDAATVGMRDIARAA
MLBr_02568|M.leprae_Br4923 -MAG-------GAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEA
: : .* : .: :* .
Mb1805c|M.bovis_AF2122/97 HCSRATIYRRAGGKAQIRDVVLTRAAARIADGVRSDVETLRG-RERVVAA
MAB_1938c|M.abscessus_ATCC_199 GCSRATVYRHVGGKTAIVDAVLARNIAKVTADIQRAVQSADA-RRRAVVA
MMAR_4185|M.marinum_M GCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDIDDPRDQLITS
MUL_4487|M.ulcerans_Agy99 GCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDIDDPRDQLITS
MAV_1403|M.avium_104 GCSRATLYRYFENREALRTAYVHREANRLGRAIMEQIDGIDEPRQRLTAS
Rv1255c|M.tuberculosis_H37Rv GCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEPAERLLVS
Mflv_2228|M.gilvum_PYR-GCK GCSRATLYRYFENREALYTAYVHRESYRLYREMTEQIMSFDDPRERLIEG
Mvan_4466|M.vanbaalenii_PYR-1 GCSRATLYRYFENREALYTAYVHREAYRLYVEMTDQITSIADPRERLIEG
MSMEG_5040|M.smegmatis_MC2_155 GCSRATLYRYFENRDALYTAYVHREARRVYQEVSDQVVGIGDPAERLMEG
TH_2228|M.thermoresistible__bu GCSRATLYRYFDSREALHTAYVHREARRLYRELGPRLAAIGDPQNRLIEG
MLBr_02568|M.leprae_Br4923 QISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNT
*:. :* .: : . : * :. : :
Mb1805c|M.bovis_AF2122/97 ILLSLQRIRSD--PLGKLMFGSIHGGAGELAWLTESPLLADFATELTGIA
MAB_1938c|M.abscessus_ATCC_199 ITASLTAIRHD--PVISTMIATMSP-TSLGSYLNASSEIPRSASAFTGLA
MMAR_4185|M.marinum_M ITATLRMVRQR--PALAAWFASTRP-PIGGELAGQSEVIAGLAAAFLQSL
MUL_4487|M.ulcerans_Agy99 ITATLRMVRQR--PALAAWFASTRP-PIGGELAGQSEVIAGLAAAFLQSL
MAV_1403|M.avium_104 ITTTLRMVRGN--PALASWFAVTRP-PIAGELAEHSEVITALAAAFVGSL
Rv1255c|M.tuberculosis_H37Rv ITTTLRMVRDN--PALAAWFTTTRP-PIGGEMAGRSEVIAALAAAFLNSL
Mflv_2228|M.gilvum_PYR-GCK MLSSLRNVRES--PALSSWFATTQR-PIGAEMAEQSEVIKALTEAFVISL
Mvan_4466|M.vanbaalenii_PYR-1 MLASLRNVRES--PALASWFATTQR-PIGAEMAEESEVIKALTEAFVISL
MSMEG_5040|M.smegmatis_MC2_155 VITALRAVRCS--PALSSWFAATQR-PIGGEMAEHSEVIRALVEGFVRSL
TH_2228|M.thermoresistible__bu ILAALDAVREN--PALSSWFAAGHR-PVGAELADRSEVIHGLVAGFLRSQ
MLBr_02568|M.leprae_Br4923 IVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVG
: * : . : . : . :
Mb1805c|M.bovis_AF2122/97 G----------------GDPQGAKWVVRVVLSLMYWPAENDEAERRLVEK
MAB_1938c|M.abscessus_ATCC_199 ------------------DETAAQWISRVVMALLFWPTSDPAQESEMIER
MMAR_4185|M.marinum_M G-PEAPAA----------VERRARWTVRVIVSLLMFPGQDEADERAMLEE
MUL_4487|M.ulcerans_Agy99 G-PEAPAA----------VERRARWTVRVIVSLLMFPGQDEADERAMLEE
MAV_1403|M.avium_104 G-PEEPAV----------VERRARWVVRVITSLLLFPGHDEADERAMIEE
Rv1255c|M.tuberculosis_H37Rv G-PDDPTT----------VERRARWVVRMLTSLLMFPGRDEADERAMIAE
Mflv_2228|M.gilvum_PYR-GCK G-PDDADARASGATGEGSVAHRSRWLVRVMTSLMLFPGHDEADERAMLEE
Mvan_4466|M.vanbaalenii_PYR-1 G-PDDAEL----------VAHRARWLVRVMTSLMLFPGHDETDERAMLEE
MSMEG_5040|M.smegmatis_MC2_155 GSPTDADD-------DAAVGRRARWLVRVMVSLLVFPGVDEADERTMLAD
TH_2228|M.thermoresistible__bu GFDDDG--------------RRARWLVRVIVSLLLFPGRDEAEERALLED
MLBr_02568|M.leprae_Br4923 TRSSRPDH------EYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMIN
. : : : ::
Mb1805c|M.bovis_AF2122/97 YVAPAFAEQS------------------------------
MAB_1938c|M.abscessus_ATCC_199 FVYPVLKDATASRVSASATSESTISPARTATFDSSEDDSP
MMAR_4185|M.marinum_M FVAPVVTPFPTRR---------------------------
MUL_4487|M.ulcerans_Agy99 FVAPVVTPFPTRR---------------------------
MAV_1403|M.avium_104 FVVPIVTPVSARG---------------------------
Rv1255c|M.tuberculosis_H37Rv FVVPIVTPASAAARKAGHPGPE------------------
Mflv_2228|M.gilvum_PYR-GCK FVVPIVLPRRQADQATQ-----------------------
Mvan_4466|M.vanbaalenii_PYR-1 FVVPTVLPSRHAAR--------------------------
MSMEG_5040|M.smegmatis_MC2_155 FVAPLVVG-AQAAQ--------------------------
TH_2228|M.thermoresistible__bu FVVPAVAQATE-----------------------------
MLBr_02568|M.leprae_Br4923 LFWHGLKGAPADRDFGPSIVAG------------------
. .