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MAGDWLAARRTEVAADRILDAAGELFAAQPAATVGMHEIASAAGCSRATLYRYFENREALYTAYVHREAY RLYVEMTDQITSIADPRERLIEGMLASLRNVRESPALASWFATTQRPIGAEMAEESEVIKALTEAFVISL GPDDAELVAHRARWLVRVMTSLMLFPGHDETDERAMLEEFVVPTVLPSRHAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4466 | - | - | 100% (193) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3780 | - | 5e-15 | 28.49% (179) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0372 | - | 8e-09 | 25.63% (199) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1805c | - | 5e-14 | 27.87% (183) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2228 | - | 2e-93 | 86.07% (201) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 3e-64 | 62.89% (194) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00717 | - | 3e-08 | 35.40% (113) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1938c | - | 7e-18 | 31.25% (192) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4185 | - | 2e-61 | 63.59% (184) | transcriptional regulatory protein |
| M. avium 104 | MAV_1403 | - | 6e-63 | 64.13% (184) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5040 | - | 4e-69 | 68.75% (192) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2228 | - | 1e-63 | 65.41% (185) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4487 | - | 1e-61 | 63.59% (184) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1805c|M.bovis_AF2122/97 -MPG----NDWIVGGNRRTIAAER---IYAAATDLITRYGLNALDIDKLA
MAB_1938c|M.abscessus_ATCC_199 MSPY----ADWLHGSDRHTIAADR---IVSVAAKQIARHGLDRLNLDAVA
Mvan_4466|M.vanbaalenii_PYR-1 -MAG-----DWLAA-RRTEVAADR---ILDAAGELFAAQPAATVGMHEIA
Mflv_2228|M.gilvum_PYR-GCK -MAG-----DWLAA-RRTEVAADR---ILDAAGELFAAQSAATVGMHEIA
MSMEG_5040|M.smegmatis_MC2_155 -MA------DWLAG-RRGEVAADL---ILDAADALFARKDAATVGMHEIA
TH_2228|M.thermoresistible__bu -MTG-----NWLAD-RRTEVAAER---ILDAAHELFTRHDAATVGMRDIA
MMAR_4185|M.marinum_M -MG----RTDWLAA-HRSEVAADR---ILDAAERLYTEHDPASIGMNEIA
MUL_4487|M.ulcerans_Agy99 -MG----RTDWLAA-HRSEVAADR---ILDAAERLYTEHDPASIGMNEIA
MAV_1403|M.avium_104 -MPGARRSTDWLSG-HRNEAAVDR---ILDAAQELYTQRDSESIGMNEIA
Rv1255c|M.tuberculosis_H37Rv -MAG----TDWLSA-RRTELAADR---ILDAAERLFTQRDPASIGMNEIA
MLBr_00717|M.leprae_Br4923 -----------MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIA
: * . : : . : : :*
Mb1805c|M.bovis_AF2122/97 REVHCSRATIYRRAGGKAQIRDVVLTRAAARIADGVRSDVETLRG-RERV
MAB_1938c|M.abscessus_ATCC_199 REAGCSRATVYRHVGGKTAIVDAVLARNIAKVTADIQRAVQSADA-RRRA
Mvan_4466|M.vanbaalenii_PYR-1 SAAGCSRATLYRYFENREALYTAYVHREAYRLYVEMTDQITSIADPRERL
Mflv_2228|M.gilvum_PYR-GCK AAAGCSRATLYRYFENREALYTAYVHRESYRLYREMTEQIMSFDDPRERL
MSMEG_5040|M.smegmatis_MC2_155 AAAGCSRATLYRYFENRDALYTAYVHREARRVYQEVSDQVVGIGDPAERL
TH_2228|M.thermoresistible__bu RAAGCSRATLYRYFDSREALHTAYVHREARRLYRELGPRLAAIGDPQNRL
MMAR_4185|M.marinum_M RAAGCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDIDDPRDQL
MUL_4487|M.ulcerans_Agy99 RAAGCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDIDDPRDQL
MAV_1403|M.avium_104 RAAGCSRATLYRYFENREALRTAYVHREANRLGRAIMEQIDGIDEPRQRL
Rv1255c|M.tuberculosis_H37Rv KAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEPAERL
MLBr_00717|M.leprae_Br4923 ERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMFEEV
. *** :*: .: : . : :: .
Mb1805c|M.bovis_AF2122/97 VAAILLSLQRIRSDP--LGKLMFGSIHGGAGELAWLTESP--LLADFATE
MAB_1938c|M.abscessus_ATCC_199 VVAITASLTAIRHDP--VISTMIATMSP-TSLGSYLNASS--EIPRSASA
Mvan_4466|M.vanbaalenii_PYR-1 IEGMLASLRNVRESP--ALASWFATTQR-PIGAEMAEESE--VIKALTEA
Mflv_2228|M.gilvum_PYR-GCK IEGMLSSLRNVRESP--ALSSWFATTQR-PIGAEMAEQSE--VIKALTEA
MSMEG_5040|M.smegmatis_MC2_155 MEGVITALRAVRCSP--ALSSWFAATQR-PIGGEMAEHSE--VIRALVEG
TH_2228|M.thermoresistible__bu IEGILAALDAVRENP--ALSSWFAAGHR-PVGAELADRSE--VIHGLVAG
MMAR_4185|M.marinum_M ITSITATLRMVRQRP--ALAAWFASTRP-PIGGELAGQSE--VIAGLAAA
MUL_4487|M.ulcerans_Agy99 ITSITATLRMVRQRP--ALAAWFASTRP-PIGGELAGQSE--VIAGLAAA
MAV_1403|M.avium_104 TASITTTLRMVRGNP--ALASWFAVTRP-PIAGELAEHSE--VITALAAA
Rv1255c|M.tuberculosis_H37Rv LVSITTTLRMVRDNP--ALAAWFTTTRP-PIGGEMAGRSE--VIAALAAA
MLBr_00717|M.leprae_Br4923 RVGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSR
.: : : * . . : :
Mb1805c|M.bovis_AF2122/97 LTGIAG----------------GDPQGAKWVVR--------VVLSLMYWP
MAB_1938c|M.abscessus_ATCC_199 FTGLA------------------DETAAQWISR--------VVMALLFWP
Mvan_4466|M.vanbaalenii_PYR-1 FVISLG-PDDAEL----------VAHRARWLVR--------VMTSLMLFP
Mflv_2228|M.gilvum_PYR-GCK FVISLG-PDDADARASGATGEGSVAHRSRWLVR--------VMTSLMLFP
MSMEG_5040|M.smegmatis_MC2_155 FVRSLGSPTDADD-------DAAVGRRARWLVR--------VMVSLLVFP
TH_2228|M.thermoresistible__bu FLRSQGFDDDG--------------RRARWLVR--------VIVSLLLFP
MMAR_4185|M.marinum_M FLQSLG-PEAPAA----------VERRARWTVR--------VIVSLLMFP
MUL_4487|M.ulcerans_Agy99 FLQSLG-PEAPAA----------VERRARWTVR--------VIVSLLMFP
MAV_1403|M.avium_104 FVGSLG-PEEPAV----------VERRARWVVR--------VITSLLLFP
Rv1255c|M.tuberculosis_H37Rv FLNSLG-PDDPTT----------VERRARWVVR--------MLTSLLMFP
MLBr_00717|M.leprae_Br4923 IGDVVSVVPESKLHP-------DIERDLRVIVHGWLAFTFEVCRQRIMDP
: : : : : *
Mb1805c|M.bovis_AF2122/97 AENDEAERRLVEKYVAPAFAEQS---------------------------
MAB_1938c|M.abscessus_ATCC_199 TSDPAQESEMIERFVYPVLKDATASRVSASATSESTISPARTATFDSSED
Mvan_4466|M.vanbaalenii_PYR-1 GHDETDERAMLEEFVVPTVLPSRHAAR-----------------------
Mflv_2228|M.gilvum_PYR-GCK GHDEADERAMLEEFVVPIVLPRRQADQATQ--------------------
MSMEG_5040|M.smegmatis_MC2_155 GVDEADERTMLADFVAPLVVG-AQAAQ-----------------------
TH_2228|M.thermoresistible__bu GRDEAEERALLEDFVVPAVAQATE--------------------------
MMAR_4185|M.marinum_M GQDEADERAMLEEFVAPVVTPFPTRR------------------------
MUL_4487|M.ulcerans_Agy99 GQDEADERAMLEEFVAPVVTPFPTRR------------------------
MAV_1403|M.avium_104 GHDEADERAMIEEFVVPIVTPVSARG------------------------
Rv1255c|M.tuberculosis_H37Rv GRDEADERAMIAEFVVPIVTPASAAARKAGHPGPE---------------
MLBr_00717|M.leprae_Br4923 STDADRLADSCAHALLDAIARVPEISKELADAMAIARQPPQ---------
: : .
Mb1805c|M.bovis_AF2122/97 ---
MAB_1938c|M.abscessus_ATCC_199 DSP
Mvan_4466|M.vanbaalenii_PYR-1 ---
Mflv_2228|M.gilvum_PYR-GCK ---
MSMEG_5040|M.smegmatis_MC2_155 ---
TH_2228|M.thermoresistible__bu ---
MMAR_4185|M.marinum_M ---
MUL_4487|M.ulcerans_Agy99 ---
MAV_1403|M.avium_104 ---
Rv1255c|M.tuberculosis_H37Rv ---
MLBr_00717|M.leprae_Br4923 ---