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LASAATDLAGIGSALSAANAAAAAPTTAMLAACADEVSAVVASLFARHAQAYQALSLQATAFHQQFVQAL TGAGGAYAAAEAVNAAVAQSVQQDVLNVINAPTQALFDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1214c | PE14 | - | 100% (110) | PE FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1087 | PE_PGRS21 | 9e-38 | 70.91% (110) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 8e-37 | 68.81% (109) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1116 | PE_PGRS21 | 9e-38 | 70.91% (110) | PE-PGRS family protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | MLBr_01183 | - | 6e-13 | 40.48% (84) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4224 | - | 2e-37 | 70.00% (110) | PE-PGRS family protein |
| M. avium 104 | MAV_2915 | - | 8e-17 | 47.13% (87) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0063 | - | 2e-05 | 40.43% (94) | PE family protein |
| M. thermoresistible (build 8) | TH_3343 | - | 5e-05 | 37.68% (69) | PUTATIVE PE domain protein |
| M. ulcerans Agy99 | MUL_4524 | - | 4e-35 | 67.27% (110) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1214c|M.tuberculosis_H37Rv ----------MLASAATDLAGIGSALSAANAAAAAPTTAMLAACADEVSA
Mb1116|M.bovis_AF2122/97 -MSFVVVAPEVLAAAASDLAGIGSTLAQANAAALAPTTAVLAAGADEVSA
MMAR_4224|M.marinum_M -MSFLVTAPEILAAAATDLDGIGAAIGAANAAAAAPTTAVLAAGADEISA
MUL_4524|M.ulcerans_Agy99 -MSYLVAVPEMLASAALDLDNIGSTITAANAAAAAPTTAVLAAGADEISA
MLBr_01183|M.leprae_Br4923 MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSI
MAV_2915|M.avium_104 -MMYVTAQPEAMNAAADRLQQIGTALAAQTGANSAPMTGVVPAAADPVSL
MSMEG_0063|M.smegmatis_MC2_155 -MQPMTHNPGAEAVAAQVIANAARGLAGG-TTASAAVTALVPAGADEVSA
TH_3343|M.thermoresistible__bu -----------VGIGSQVIANGTRGLAVG-TAASAEVTALVPAGADEVSA
.: : : * : .. ** :*
Rv1214c|M.tuberculosis_H37Rv VVASLFARHAQAYQALSLQATAFHQQFVQALTGAGGAYAAAEAVNAAVAQ
Mb1116|M.bovis_AF2122/97 AIASLFGAHGQAYQAVSAQMSAFHAQFMQALTGAGGAYAAAEAVNVSAAQ
MMAR_4224|M.marinum_M AMASLFTAHAQAYQGLSVQVGAFHNQFVQALTGAGGAYAAAEAANVSPLQ
MUL_4524|M.ulcerans_Agy99 AVAALFTGHAQAYQWLGAQAGAFHSQFIQALTGSGSAYAAAEAANASPLQ
MLBr_01183|M.leprae_Br4923 LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETANHDSL-
MAV_2915|M.avium_104 LAAARFAQHGQAFQAVSAEAAAVHEMFVTTLQTSAGSYAGTEAANAAAAR
MSMEG_0063|M.smegmatis_MC2_155 LAAVAFASEGVEALAANAFAQEELTRAGAAFAEIAGIYNAVDAANAATM-
TH_3343|M.thermoresistible__bu QAAAAFAKEGMEALALNTFAQEELARAGAAVVQIAGIYDAVDAANAGTLA
* * .. :. .. * ..::.*
Rv1214c|M.tuberculosis_H37Rv SVQQDVLNVINAPTQALFDR------------------------------
Mb1116|M.bovis_AF2122/97 SVEQDLLAAINARFERIFGRPLIGDGANGGPGQDGGPGGLLYGNGGNGGT
MMAR_4224|M.marinum_M AAAQDMLTAIRAPAQALLGRPLIGNGADGAPGQAGGDGGLLYGNGGNGGT
MUL_4524|M.ulcerans_Agy99 TAAQELLAVINTPTQTLLGRPLIGNGADGALGQAGGDGGLLYGNGG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 STTVGMAGGNGGAAGLIGNGGFGGGGGPGAAGGNGGAGGWLFGNGGAGGA
MMAR_4224|M.marinum_M STTAGVAGGAGGSAGLIGNGGAGGGGGAGAVGGNGGAGGWLFGNGGAGGA
MUL_4524|M.ulcerans_Agy99 ------------------------------------AGGWLFGQGGVG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 GGLGVAPGVPGGAGGAGGAGGVGGPAGLWGHGGAGGAGGAGVAGAGGFEG
MMAR_4224|M.marinum_M G--GATPGIGGG-GGAGGAGGIGGAAGLFGNGGAGGVGGD---------G
MUL_4524|M.ulcerans_Agy99 -----------------------------GNGGTGGIG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 TIGAGGAGGVGGAGGVGGAGGAGGWLYGDAGAGGDGGVGGAGGTGGLGNR
MMAR_4224|M.marinum_M GLNYYGDGGVAGAG---GDGGRGGWLHGD---GGDGGAGGDGGRG-----
MUL_4524|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 GGAGGAGGAGGVGGAGGAAGLWGGGGAGGVGGTGGGAGLGAQSVTFSSSL
MMAR_4224|M.marinum_M ----LPGGDGGSGGAGGGTGLWGSGGAGGQGGTGG---------------
MUL_4524|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 SGLSGGDGGAGGAGGAGGAGGTGGWLYGGGGAAGSGGDGGTGGQGGAGGA
MMAR_4224|M.marinum_M ----------------TGLNGNAPFADGQHPVILDGGHGGTGGNGGAAGN
MUL_4524|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 GVFSLFGSGGGPGGNGGVGGVGGVGGAGGRAGLFGVGGLGGAGGDAGDSG
MMAR_4224|M.marinum_M --------GGLLFGNGGNGGLGGMGGGGG-------NGLPSTG-------
MUL_4524|M.ulcerans_Agy99 --------------------LDGVAGHIG---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 EGGFGGPGLAGGLFGNPGNGGVGGIGGDAAAGGAGGAGGNGGWLFGNGGA
MMAR_4224|M.marinum_M ------------------------VGGDGGDGGNGGTAGNGGWLIGNGGT
MUL_4524|M.ulcerans_Agy99 -------------------------GGNAGNAGNGGTGGSGGLLFGDGGD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 GGSGGDGGAAGRGGAGNLGSAGGINAPAGNPGSGSVGIGGAGGAGGTAGL
MMAR_4224|M.marinum_M GGQGGAGFAGGTGADN-------------------VSAGRPGGAGGTG--
MUL_4524|M.ulcerans_Agy99 GGHGGAGFGGGNGSGN--------------------PIGGQGGNAGVAG-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 FGDGGAGGAGAAGGFGGISAATPSAGSEGAMGGAGGVGGNARLLGTGGAG
MMAR_4224|M.marinum_M --------------------------------GIGAGGGNAGLIGTGGSG
MUL_4524|M.ulcerans_Agy99 --------------------------------NGGAGGSAAMLFGNGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 GVGGGGGAGGDGGRGGVATPGGQGGDAGDGGAGGAGGNGGGGASGAGGWL
MMAR_4224|M.marinum_M GNGGMGGHGGDSGYG--DQTGGQGGNGGMGGAG--------GAAGNGGLL
MUL_4524|M.ulcerans_Agy99 GNGGSGGDGGHGGNSALSVPGSIGGDAGAGGTG--------GSAGKSGLL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 LGTGGAGGAGGNGGNGGKAGFSPGPTNFGLNGAGGGGGVGGNGATGPWLF
MMAR_4224|M.marinum_M LGSGSRGGDGGDGGNGGEG---RGGFSVPQHGVGGQGGTGGNGSDGGWLY
MUL_4524|M.ulcerans_Agy99 FGAGGAGGQGGGGGTGGDGGDCAGANIGGDGGAGGAGGLGGNGTDGGWLY
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 GDGG--AGGGGGAGGIGGDGGPTPGSTGAGAAGGHGGDAQLIGNGGHGGA
MMAR_4224|M.marinum_M GDGG--AGGAGGNGGFGGSGVQN----GAGGDAGSGGDSRLIGDGGAAGA
MUL_4524|M.ulcerans_Agy99 GNGGGGAGGQGGDGGHGGSPVGFDGKSGVGGDGGDGGNARIIGNGGNGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_2915|M.avium_104 --------------------------------------------------
MSMEG_0063|M.smegmatis_MC2_155 --------------------------------------------------
TH_3343|M.thermoresistible__bu --------------------------------------------------
Rv1214c|M.tuberculosis_H37Rv -------------------------------
Mb1116|M.bovis_AF2122/97 GGTG---VPNGSGGAGGLSGLLFGEPGANG-
MMAR_4224|M.marinum_M GGTG---APPGADGHSGADGLLSAALGA---
MUL_4524|M.ulcerans_Agy99 GGNGGVGSTDGDGGQGGAAGLLFGQPGSMGT
MLBr_01183|M.leprae_Br4923 -------------------------------
MAV_2915|M.avium_104 -------------------------------
MSMEG_0063|M.smegmatis_MC2_155 -------------------------------
TH_3343|M.thermoresistible__bu -------------------------------