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MSFVVVAPEVLAAAASDLAGIGSTLAQANAAALAPTTAVLAAGADEVSAAIASLFGAHGQAYQAVSAQMS AFHAQFMQALTGAGGAYAAAEAVNVSAAQSVEQDLLAAINARFERIFGRPLIGDGANGGPGQDGGPGGLL YGNGGNGGTSTTVGMAGGNGGAAGLIGNGGFGGGGGPGAAGGNGGAGGWLFGNGGAGGAGGLGVAPGVPG GAGGAGGAGGVGGPAGLWGHGGAGGAGGAGVAGAGGFEGTIGAGGAGGVGGAGGVGGAGGAGGWLYGDAG AGGDGGVGGAGGTGGLGNRGGAGGAGGAGGVGGAGGAAGLWGGGGAGGVGGTGGGAGLGAQSVTFSSSLS GLSGGDGGAGGAGGAGGAGGTGGWLYGGGGAAGSGGDGGTGGQGGAGGAGVFSLFGSGGGPGGNGGVGGV GGVGGAGGRAGLFGVGGLGGAGGDAGDSGEGGFGGPGLAGGLFGNPGNGGVGGIGGDAAAGGAGGAGGNG GAGGNGGWLFGNGGAGGSGGDGGAAGRGGAGNLGSAGGINAPAGNPGSGSVGIGGAGGAGGTAGLFGDGG AGGAGGAGAAGGFGGISAATPSAGSEGAMGGAGGVGGNARLLGTGGAGGVGGGGGAGGDGGRGGVATPGG QGGDAGDGGAGGAGGNGGGASGAGGWLLGTGGAGGAGGNGGNGGKAGFSPGPTNFGLNGAGGGGGVGGNG ATGPWLFGDGGPTPGSTGAGAAGGHGGDAQLIGNGGHGGAGGTGVPNGSGGAGGLSGLLFGEPGANG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1087 | PE_PGRS21 | - | 100% (767) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 0.0 | 59.31% (865) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 0.0 | 53.37% (802) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1116 | PE_PGRS21 | 0.0 | 96.81% (783) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-160 | 47.09% (739) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 36.96% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-54 | 37.01% (462) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_3316 | - | 0.0 | 47.77% (988) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 3e-24 | 44.12% (170) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-123 | 42.02% (771) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 4e-44 | 42.90% (317) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 51.38% (835) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-157 | 45.58% (735) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1087|M.tuberculosis_H37Rv --------------------------------------------------
Mb1116|M.bovis_AF2122/97 --------------------------------------------------
MMAR_3316|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1087|M.tuberculosis_H37Rv ----------MSFVVVAPEVLAAAASDLAGIGSTLAQANAAALAPTTAVL
Mb1116|M.bovis_AF2122/97 ----------MSFVVVAPEVLAAAASDLAGIGSTLAQANAAALAPTTAVL
MMAR_3316|M.marinum_M ----------MAFVLVAPEMVTAAASDLANIGSAINTANTAVAAPTAELL
MUL_4367|M.ulcerans_Agy99 ----------MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVL
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTG
Rv1087|M.tuberculosis_H37Rv AAGADEVSAAIASLFGAHGQAYQAVSAQMSAFHAQFMQALTGAGGAYAAA
Mb1116|M.bovis_AF2122/97 AAGADEVSAAIASLFGAHGQAYQAVSAQMSAFHAQFMQALTGAGGAYAAA
MMAR_3316|M.marinum_M AAGTDEVSEAIASLFSGHALDYQNLGARMTAFHDQFVAALTAGGGLYSSA
MUL_4367|M.ulcerans_Agy99 PAAGDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR--
Rv1087|M.tuberculosis_H37Rv EAVN-----------------------------------VSAAQSVEQDL
Mb1116|M.bovis_AF2122/97 EAVN-----------------------------------VSAAQSVEQDL
MMAR_3316|M.marinum_M EAA---------------------------------------AATPLQDL
MUL_4367|M.ulcerans_Agy99 EALN-----------------------------------MWPLQELEQQA
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LLSPRD---------------------------------NDFLSHNDTDF
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------------------------DALAARRIDN
Rv1087|M.tuberculosis_H37Rv LAAIN-----------------ARFERIFG--------RPLIGDGANG--
Mb1116|M.bovis_AF2122/97 LAAIN-----------------ARFERIFG--------RPLIGDGANG--
MMAR_3316|M.marinum_M LNVVN-----------------APTQALLG--------RPLIGDGADGT-
MUL_4367|M.ulcerans_Agy99 LGVVN-----------------APSMALFG--------RPSIGNGVDGVA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGT-
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGT-
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGT-
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ASHNP----------------IASGNQVMS----------PSGNVDSFNR
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VMLVS---------------------------------AFLAAAALAQNV
Rv1087|M.tuberculosis_H37Rv GPGQDGGPGGLLYGNGGNGGTSTTVGMAGGNGGAAGLIG-NGGFGGGGGP
Mb1116|M.bovis_AF2122/97 GPGQDGGPGGLLYGNGGNGGTSTTVGMAGGNGGAAGLIG-NGGFGGGGGP
MMAR_3316|M.marinum_M APGQAGGAGGLLYGNGGNGAAGTNPGVAGGAGGAAGLIG-NGGAGGIGGA
MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGGLG-AAGANGGAGGSAGLIG-TGGVGGAGGV
Mflv_5091|M.gilvum_PYR-GCK GQN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLG
Mvan_1264|M.vanbaalenii_PYR-1 GQN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLG
MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWA
TH_3810|M.thermoresistible__bu -----------VDGDGG----------SGGRTGLFSKLS-RGGDGGDGGL
MAB_4284c|M.abscessus_ATCC_199 GPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASG-QGSTAVNGDV
MLBr_01183|M.leprae_Br4923 ---------MPLFLNAEPQALTAAANTLEGLSAATVASN-AAAAQLTTEI
MAV_4827|M.avium_104 GGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQ
: . .
Rv1087|M.tuberculosis_H37Rv ------GAAGGNGGAGG--WLFGNGGAGGAGGLGVAPGVPGGA----GGA
Mb1116|M.bovis_AF2122/97 ------GAAGGNGGAGG--WLFGNGGAGGAGGLGVAPGVPGGA----GGA
MMAR_3316|M.marinum_M ------GGSGGAGGTGG--WLYGNGGAGGAGGAG-APGLVSFN----GSN
MUL_4367|M.ulcerans_Agy99 GAAGMTGGSGGAGGGGG--WLWGAGGSGGAAGAGGSGGSGGWL----WGN
Mflv_5091|M.gilvum_PYR-GCK ------GGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVA
Mvan_1264|M.vanbaalenii_PYR-1 ------SGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVA
MSMEG_0868|M.smegmatis_MC2_155 ------GLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTG
TH_3810|M.thermoresistible__bu ------GGNGGHGGGTGIISLLSLAGNGGNGGNGYRTTDNNAL------D
MAB_4284c|M.abscessus_ATCC_199 RDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVT---VVDD
MLBr_01183|M.leprae_Br4923 ------APPAADDVSILLAHFFS--GHGRQYQAHASQGATNHQ------D
MAV_4827|M.avium_104 LSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVS----VAE
. .
Rv1087|M.tuberculosis_H37Rv GGAGGVGGPAGLWGHGG--AGGAGGAGVAGAGG-----------------
Mb1116|M.bovis_AF2122/97 GGAGGVGGPAGLWGHGG--AGGAGGAGVAGAGG-----------------
MMAR_3316|M.marinum_M GGNGGNGGAAGWWGTGG--AGGAGGEGGAAGGGPAGIAYGQTGGVGGNGG
MUL_4367|M.ulcerans_Agy99 AGQTAGAGVGGAGGAGG--AGDAGDQGVSGVAPGEAGAVGFAGGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK GATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------
Mvan_1264|M.vanbaalenii_PYR-1 GATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------
MSMEG_0868|M.smegmatis_MC2_155 GTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVL
TH_3810|M.thermoresistible__bu GGHGGNGGNVGFFSLFN---------------------------------
MAB_4284c|M.abscessus_ATCC_199 HSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQAN------------
MLBr_01183|M.leprae_Br4923 LIQSLLTSSSAYAGTET---------------------------------
MAV_4827|M.avium_104 EPETALARGAALAAANAPLFASSTAALAYAQDP-----------------
Rv1087|M.tuberculosis_H37Rv ---------FEGTIGAGGAGGVGG-------------AGGVGGAGGAGG-
Mb1116|M.bovis_AF2122/97 ---------FEGTIGAGGAGGVGG-------------AGGVGGAGGAGG-
MMAR_3316|M.marinum_M NGGN--GGWFAGNAGAGGNGGVGGDGNAADNGL----VGGTGGVGGAGGS
MUL_4367|M.ulcerans_Agy99 AGGNGVGGGVNGAGGAGGAGGVGGGGGAGASGVGAGVAGGDGGTGGAGGA
Mflv_5091|M.gilvum_PYR-GCK ------AVGSAGAAGEAGETGTWG--NAGLP-------GKAGDAGGAG--
Mvan_1264|M.vanbaalenii_PYR-1 ------AVGSAGTAGSAGAPGVWG--NAGLP-------GAAGAAGGAG--
MSMEG_0868|M.smegmatis_MC2_155 IAGPNVTVGSETRGGTGGAGGTGGQSTAAGP-------GKGGGGGGGGGG
TH_3810|M.thermoresistible__bu ---------------LGGAGGWGG--------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------IGTSTSAGGSAAVGG--------------------------
MLBr_01183|M.leprae_Br4923 ----------------ANHDSL----------------------------
MAV_4827|M.avium_104 --------------GTGAVDQYSLP-------------------------
.
Rv1087|M.tuberculosis_H37Rv -WLYGDA-------GAGGDGGVGG------AGGTGGLGNRGG--------
Mb1116|M.bovis_AF2122/97 -WLYGDA-------GAGGDGGVGG------AGGTGGLGNRGG--------
MMAR_3316|M.marinum_M AGLFGDG-------GAGGQGGDGGGVTGLVGAGHGGAGGDGGR-------
MUL_4367|M.ulcerans_Agy99 AGVGGAA-------GTGGTGGAAGVAGTGGDGGDGGAGGAGSDA------
Mflv_5091|M.gilvum_PYR-GCK --------------AVGAAGAAG------TVGTAGATGGTG---------
Mvan_1264|M.vanbaalenii_PYR-1 --------------AIGTAGVAG------AAGTAGATGGTG---------
MSMEG_0868|M.smegmatis_MC2_155 AILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv1087|M.tuberculosis_H37Rv ---------AGGAGGAGGVGGAGGAAG-------------LWGGGGAGG-
Mb1116|M.bovis_AF2122/97 ---------AGGAGGAGGVGGAGGAAG-------------LWGGGGAGG-
MMAR_3316|M.marinum_M ---------AGWLSGNAGAGGGGGAGG-------------AVDNHGSGGD
MUL_4367|M.ulcerans_Agy99 ----SLAGQAGFAGGSGGAGGVGGSAG-------------AGGVNGSGG-
Mflv_5091|M.gilvum_PYR-GCK ------TGANGGAGGVGGVGGTGAAG--------------AAGGAGGLGE
Mvan_1264|M.vanbaalenii_PYR-1 ------VGGNGGAGQAGGIGGTGAAG--------------AAGQAGTAGE
MSMEG_0868|M.smegmatis_MC2_155 TAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGI
TH_3810|M.thermoresistible__bu -------------SGVDGVDVVGGNPD-----------------------
MAB_4284c|M.abscessus_ATCC_199 ---------NAGLAGNAGLAGNAGLAG-------------NAGLAGNAGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------DYLYVPVDPEPGDDE------------LAYSAVGEEDA
Rv1087|M.tuberculosis_H37Rv VGGTGGGAGLGAQS-VTFS-SSLSGLSGGDGGAG----------------
Mb1116|M.bovis_AF2122/97 VGGTGGGAGLGAQS-VTFS-SSLSGLSGGDGGAG----------------
MMAR_3316|M.marinum_M YAGGGGAGGSGGAA-GLFG-NGAAGGAGGAGGASQT------------FT
MUL_4367|M.ulcerans_Agy99 DGGAGAAGGAGGAS-ATVAGSGGVGGDGGAGGAAGGGVGAASLGGDGGHA
Mflv_5091|M.gilvum_PYR-GCK TGTTGGAGGVGGQ--GTAGGTGGVGGIGGAGSTG----------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTGGVGGIGGQ--GTEGGTGGVGGVGGVGATG----------------
MSMEG_0868|M.smegmatis_MC2_155 DGGTGGAGGMGEIYSGADGEATGISAGGDGGSAT----------------
TH_3810|M.thermoresistible__bu -GGTPGAHG--------ESHTPGVYTDRQ---------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAG--NAGLAGNAGLAGNAGLAG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVG-----------ISAVL
Rv1087|M.tuberculosis_H37Rv GAGGAGGAG-------GTG---------------GWLYGGGGAAGSGGDG
Mb1116|M.bovis_AF2122/97 GAGGAGGAG-------GTG---------------GWLYGGGGAAGSGGDG
MMAR_3316|M.marinum_M GAGGAGGTG-------GAG---------------GWLYGNGGAGGAGGAS
MUL_4367|M.ulcerans_Agy99 GAGGAGGEG-------LSGGFNTG--------AAGGIGGAGGAGGTGGDS
Mflv_5091|M.gilvum_PYR-GCK AVGGVGGKG----IQGGQG-------------LQGGKGGDGGAGGKGGDA
Mvan_1264|M.vanbaalenii_PYR-1 GAGGVGGKG----IQGGQG-------------LQGGQGGDGGTGGTGGDA
MSMEG_0868|M.smegmatis_MC2_155 GADSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDA
TH_3810|M.thermoresistible__bu GEDGEDGTG----------------------------TGIGGRGGNGGSS
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAG---------------------------LAGNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ALEIALAIG---------------------------IRTTGTVALQPTPN
Rv1087|M.tuberculosis_H37Rv GT-------------------------GGQGGAGG-----AGVFSLFGSG
Mb1116|M.bovis_AF2122/97 GT-------------------------GGQGGAGG-----AGVFSLFGSG
MMAR_3316|M.marinum_M GAGIG------------------GDSLGGSGGNGGN----GGISGLIGNG
MUL_4367|M.ulcerans_Agy99 GGVGG------------------VNGDGGAGGGGGRGGDGGSSTSTSGVG
Mflv_5091|M.gilvum_PYR-GCK DSMGS------------------AGATGGKGGNGGN----GGRGGLFG--
Mvan_1264|M.vanbaalenii_PYR-1 TSMGE------------------AGATGGKGGNGGN----GGRGSLFG--
MSMEG_0868|M.smegmatis_MC2_155 LVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGF----TNIAAIHGSI
TH_3810|M.thermoresistible__bu SGTHP------------------------MAEDGEH------VKALDGRP
MAB_4284c|M.abscessus_ATCC_199 GN-------------------------AGLAGN-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 QHLIVP---------------------TEQAPAPPP--------------
Rv1087|M.tuberculosis_H37Rv --------------GGPGGNGG----------------------VGGVGG
Mb1116|M.bovis_AF2122/97 --------------GGPGGNGG----------------------VGGVGG
MMAR_3316|M.marinum_M G------------AGGAGGNGS----------------------AAGYNG
MUL_4367|M.ulcerans_Agy99 G------------AGGAGGNGGNAGF---------------GVSAGGTGG
Mflv_5091|M.gilvum_PYR-GCK -------------KGGNAGNGAD----------------------GGTGG
Mvan_1264|M.vanbaalenii_PYR-1 -------------RGGNAGNGGN----------------------GGTGG
MSMEG_0868|M.smegmatis_MC2_155 TDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGG
TH_3810|M.thermoresistible__bu --------------GLDGGNGS-------------------------HGG
MAB_4284c|M.abscessus_ATCC_199 --------------AGLAGNAG----------------------LAGNAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------VQASAPQPK----------------------ISVPEP
Rv1087|M.tuberculosis_H37Rv VGGAGGRAG-LFGVGGLGGAGG--------------DAGDSGEGGFGGPG
Mb1116|M.bovis_AF2122/97 VGGAGGRAG-LFGVGGLGGAGG--------------DAGDSGEGGFGGPG
MMAR_3316|M.marinum_M YSGNGGNGG-NGGAAQLIGAGG--------------GGGVAGIGGAGGTG
MUL_4367|M.ulcerans_Agy99 SAGDGGAGGGAGGVDGVGGASG--------------NGGAAGAGGAGGSG
Mflv_5091|M.gilvum_PYR-GCK AGGAGGTGG-TGGAGGTGG-----------------TGGTGGIGGAGSTG
Mvan_1264|M.vanbaalenii_PYR-1 NGGNGGTGG-TGGNGGTGG-----------------TGGTGGIGGAGSTG
MSMEG_0868|M.smegmatis_MC2_155 DGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTF
TH_3810|M.thermoresistible__bu NGGHGGRGG---------------------------FLGIGGSGGWGGHG
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAG---------------------------NAGLAGNAGLAGNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VAAPKPLSP-----------------------------PVAAPLPAAPPP
Rv1087|M.tuberculosis_H37Rv LAGGLFGNPG-NGGVGG-----------IGGDAAAGGAGGAGGNGGAGGN
Mb1116|M.bovis_AF2122/97 LAGGLFGNPG-NGGVGG-----------IGGDAAAGGAG------GAGGN
MMAR_3316|M.marinum_M AAAGVTGSAG-ASGVGGRLYSGNGIPDIFGRPLIGDGADGAPGTGQAGGD
MUL_4367|M.ulcerans_Agy99 IGAGIDGGAGGAGGTGG--AAGFPGGGGTTGAWGTGGAGGAGGAGGAGDH
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGG-TGGTGGTG-----GTGGTGGTGGTGGKGGTGGTGGAGGT
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGG-TGGTGGTG-----GTGGTGGTGGTGGKGGTGGTGGDGGT
MSMEG_0868|M.smegmatis_MC2_155 VNAGANGNGG-AGGAGGVSE----GEGGTGGHGGDGGRGGDGALGGNGGT
TH_3810|M.thermoresistible__bu GNGGDTDADG----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AVAGNAAVAG------------------NAAVAGNAAVGGVLNTGVSGAI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 AAPPLPEAPP------------------IPAAPPVVPVPVVVPPVPVPVP
Rv1087|M.tuberculosis_H37Rv GGWLFGNGGAGGS------GGDGGAA------GRGGAGNLGSAGGIN---
Mb1116|M.bovis_AF2122/97 GGWLFGNGGAGGS------GGDGGAA------GRGGAGNLGSAGGIN---
MMAR_3316|M.marinum_M GGWLYGNGGAGGSGAAGQAGGAGGAAGLIGNGGAGGTGGSGAAGGSG---
MUL_4367|M.ulcerans_Agy99 GGVGVNPGDSGTAGWAGGAGGAGGAGGSAAFNGVNGAGGAGGNGGAG---
Mflv_5091|M.gilvum_PYR-GCK G----GDGGTGGT------GGTGGTG---------GTGGTGGTGGAG---
Mvan_1264|M.vanbaalenii_PYR-1 G----GTGGTGGT------GGTGGTG---------GTGGTGGTGGAG---
MSMEG_0868|M.smegmatis_MC2_155 GGVGLGNGGKGGN------GGNGGNGGTYVDPSHTGAGGNGGNGGAGRIR
TH_3810|M.thermoresistible__bu -----GNGGDGGN------GGSAGRG---------GTGGLRGVFGIN---
MAB_4284c|M.abscessus_ATCC_199 GGSSHVGGAINES-----LGGSGSVG---------GSTAVGGGAHTG---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VRIPVPDPVSPPQ-----LLAPPRLSVPQPVQPPVRVPQPPSPPQVG---
Rv1087|M.tuberculosis_H37Rv ---------APAGNPGSG-----------------------SVGIGGAGG
Mb1116|M.bovis_AF2122/97 ---------APAGNPGSG-----------------------SVGIGGAGG
MMAR_3316|M.marinum_M ---------AAGGNGGAGGWLFGNGGTGGTGGDAVAGLPGLNGGNGGNGG
MUL_4367|M.ulcerans_Agy99 ---------GGGGAGASGIGAGVAGGDGGTGGTGGAAGTGGAAGTGGTGG
Mflv_5091|M.gilvum_PYR-GCK --------DGTGGTGGTGG----------------------TGGQGGQGG
Mvan_1264|M.vanbaalenii_PYR-1 --------DGLGGTGGTGG----------------------TGGFGGQGG
MSMEG_0868|M.smegmatis_MC2_155 VNNGTATGTATGGNGGNGGN------------------GDADGHRGGKGG
TH_3810|M.thermoresistible__bu -----------GGNGRAG--------------------------LGGRGX
MAB_4284c|M.abscessus_ATCC_199 ----------VGGGVSTG---------------------------VGVGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------GTVPQSPPQ---------------------HQTPPGEGT
Rv1087|M.tuberculosis_H37Rv AGG-----------------TAGLFGDGG-AGGAGGAG------------
Mb1116|M.bovis_AF2122/97 AGG-----------------TAGLFGDGG-AGGAG---------------
MMAR_3316|M.marinum_M AGG-----------------AAGWWGHGG-IGGQGGTGG-----------
MUL_4367|M.ulcerans_Agy99 AAG-----------------AAGSAGDGG-AGGAGGAGDDGS----AGVV
Mflv_5091|M.gilvum_PYR-GCK QGG-----------------TGGTGGQGG-LGGGGGTG------------
Mvan_1264|M.vanbaalenii_PYR-1 QGG-----------------TGGTGGQGG-LGGVGGTG------------
MSMEG_0868|M.smegmatis_MC2_155 DGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQ
TH_3810|M.thermoresistible__bu XXX------------------------GGGVGAAVRSG------------
MAB_4284c|M.abscessus_ATCC_199 HVG------------------------GGISESLGGSG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PPK---------------------------PDGPGNYG------------
Rv1087|M.tuberculosis_H37Rv -----------AAGGFG-----GISAATPSAGSEGAMG------------
Mb1116|M.bovis_AF2122/97 -----------AAGGFG-----GISAATPSAGSEGAMG------------
MMAR_3316|M.marinum_M -----------AAGGNP-----GIYAGNAGTGGDGGAGGWLFGDAGAGGQ
MUL_4367|M.ulcerans_Agy99 SGDPGTAGKAGGAGGAGGVGGNGVAGGVNGSGGAGGAGG-AGGTGGAGAS
Mflv_5091|M.gilvum_PYR-GCK -----------GQGGTG---GTGGQGGTGGTGGTGGTG------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GTGGTG---GTGGQGGTGGTGGTGGTG------------
MSMEG_0868|M.smegmatis_MC2_155 ANPQASGTATDGHGGSG---INGGHGGNGGQGTIEANGP------SAVAS
TH_3810|M.thermoresistible__bu ------------------------NGVFSGGGGTPSAG------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------SVGGSTAVGGGAHTG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------GGHVPTPGAGGSGGSG------------
Rv1087|M.tuberculosis_H37Rv --------------------GAGGVGGNARLLGTGGAGGVGGGGGAG---
Mb1116|M.bovis_AF2122/97 --------------------GAGGVGGNARLLGTGGAGGVGGGGGAG---
MMAR_3316|M.marinum_M GGTGGAANDPLVTSSTGGSGGAGGNGGAAGLFGAGGAGGTGGTAGDGYLI
MUL_4367|M.ulcerans_Agy99 GVPASVDGGDGGAGGAGGAAGTGGSGGSAGNTGAGGAGGAGGAGGSAAST
Mflv_5091|M.gilvum_PYR-GCK --GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QA
Mvan_1264|M.vanbaalenii_PYR-1 --GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QA
MSMEG_0868|M.smegmatis_MC2_155 GIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKAT
TH_3810|M.thermoresistible__bu ---------------------FGVPTTIQFPAGSCTSRAVSR--------
MAB_4284c|M.abscessus_ATCC_199 ---------------------VGGGVSTGVGVGSHVGGGISESLGGS---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------GGHVPTPGAGGSGGSGGGHVPTPG----
Rv1087|M.tuberculosis_H37Rv ---GDGGRGG-----------------VATPGGQGGDAGDG---------
Mb1116|M.bovis_AF2122/97 ---GDGGRGG-----------------VATPGGQGGDAGDG---------
MMAR_3316|M.marinum_M --GGDGGNGGQ----GGYGGW------LAGSGGAGGTAGDGGAGIY----
MUL_4367|M.ulcerans_Agy99 GVNGDGGAGGA----GGVGGLGGDSAATAGGGGAGGDGGKGGAGGAGVNG
Mflv_5091|M.gilvum_PYR-GCK GTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG---
Mvan_1264|M.vanbaalenii_PYR-1 GVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG---
MSMEG_0868|M.smegmatis_MC2_155 GTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNA
TH_3810|M.thermoresistible__bu --------EG------------------IMPSSRAASARAG---------
MAB_4284c|M.abscessus_ATCC_199 -----GSVGG------------------STAVGGGAHTGVG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------------------TGGPGGTGGSGG--------
Rv1087|M.tuberculosis_H37Rv ------GAGGAGGNGGG-ASGAGGWLLGTGGAG---------------GA
Mb1116|M.bovis_AF2122/97 ------GAGGAGGNGGGGASGAGGWLLGTGGAG---------------GA
MMAR_3316|M.marinum_M ----PGGAGGTGGSGGAARFFGDGGAAGTGGVGGFGSK-------YVAGS
MUL_4367|M.ulcerans_Agy99 VGGGDGGKGGTGGAGGAGGAGSDGIIPSNGGLGGNGGNGGNGGQAFGDGV
Mflv_5091|M.gilvum_PYR-GCK ------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TT
Mvan_1264|M.vanbaalenii_PYR-1 ------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TT
MSMEG_0868|M.smegmatis_MC2_155 L---VMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAIT
TH_3810|M.thermoresistible__bu -------------AACASSTSRSRRSFCCSRA------------------
MAB_4284c|M.abscessus_ATCC_199 --------GGVNTGVGVGSHVGGGISESLGGSG---------------SV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------GHVPTPGAGTPGGSGGGHLPFPGAG-----------------
Rv1087|M.tuberculosis_H37Rv GGNGGNGGKAG--------FSPGPTNFGLNG------------AGGGG--
Mb1116|M.bovis_AF2122/97 GGNGGNGGKAG--------FSPGPTNFGLNG------------AGGGG--
MMAR_3316|M.marinum_M GGSGGTGGAAG--------WLIGNGGAGGQGGVAGTPDGVNRVFGGTG--
MUL_4367|M.ulcerans_Agy99 GGAGGIGGKGGNAAIGTIVINGGVGGAGGSGGLGGATEDGVGGVGCAG--
Mflv_5091|M.gilvum_PYR-GCK GAQGSAGTNGA---------NGANGSQGAAG-----KAGATGTTGATG--
Mvan_1264|M.vanbaalenii_PYR-1 GAQGSAGTNGA---------NGANGSQGAAG-----KAGATGTTGATG--
MSMEG_0868|M.smegmatis_MC2_155 DSTAISGHGGAG--------NGGNGGKGADG-----WVQAYDPAGPVGSK
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSTAVGGGAHT--------SAINDALGGSG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------STPGGSG----------------------
Rv1087|M.tuberculosis_H37Rv --------GVGGNGATGPWLFGDG----------------GPTPGSTG-A
Mb1116|M.bovis_AF2122/97 --------GVGGNGATGPWLFGDGGAGGGGGAGGIGG-DGGPTPGSTG-A
MMAR_3316|M.marinum_M --------GAGGTGGTAGWLYGSGGSGGAGGAG-----TASIYPGSTGGN
MUL_4367|M.ulcerans_Agy99 --------GAGGNGGRGDMLFTVGGSGGTGGDGGGGGSASGSGTGGSGGT
Mflv_5091|M.gilvum_PYR-GCK ------AAGEDGDAGSGGSG-INGGAGGAGG------------AGGEGGE
Mvan_1264|M.vanbaalenii_PYR-1 ------AAGDAGDPGSEAVD-INGGAGGAGG------------AGGEGGE
MSMEG_0868|M.smegmatis_MC2_155 IANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWK-SGGQTADGEHNT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------SVGGSTAVGGGAHTSAINESMNSSIN--------ASHSSSMN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------GGHLPTPGAGTPGGGLGGFGG------------GHAPAPG
Rv1087|M.tuberculosis_H37Rv GAAGGHGGDAQLIG-----NGGHGGAGGTG-----------VPNGS----
Mb1116|M.bovis_AF2122/97 GAAGGHGGDAQLIG-----NGGHGGAGGTG-----------VPNGS----
MMAR_3316|M.marinum_M GGNGGNGGAAQVIG-----TGGTGGTAGTGGAGGPDDPPNNIPAGNDGQD
MUL_4367|M.ulcerans_Agy99 GGVGGIGGDGKLGG-----FGGDGGDGGDGGFG--------VIGGQGGGG
Mflv_5091|M.gilvum_PYR-GCK GGDGGKGGAGAE--------GGAGGGGGAGG----------SGAGGAG--
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGAGGDGSE--------GGAGGSGGAGG----------SGTGGAG--
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGDGSEPGPGGNGAGGAGGNGGTGG----------TTAGGSGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESFGSSMGSHGAAG------TGFEAQGHAQG-----------HASETAHT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GGLGGGGGHAPAPG------GGLGGFGGGHS-------------------
Rv1087|M.tuberculosis_H37Rv --GGAGGLSG-------LLFGEPGANG----
Mb1116|M.bovis_AF2122/97 --GGAGGLSG-------LLFGEPGANG----
MMAR_3316|M.marinum_M GVGGAGGSGG-------LVFGNSGG------
MUL_4367|M.ulcerans_Agy99 GFGGLGGTGAGGAPSDKGINGEPGNPG----
Mflv_5091|M.gilvum_PYR-GCK GAGGSGGSGGSG-----GSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GAGGSGGSGGSG-----GAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGGAD-----GTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu -------------------------------
MAB_4284c|M.abscessus_ATCC_199 TLPGAEHH-----------------------
MLBr_01183|M.leprae_Br4923 -------------------------------
MAV_4827|M.avium_104 -GGGLGGLGGGHK------------------