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M. marinum M MMAR_5321 (-)

annotation: PE-PGRS family protein
coordinates: 6426029 - 6428200
length: 723

SYLLVTPELLTSAATDLEGIASALSTANLAAAVPTTGVLAAGADEVSAAVASLFAGYGQAYQSISLQANA
FQAQFIQAINGAGGAYAAAEAASTSPLQAFEDTVLGVINAPTQTLLGRPLIGDGAAGTAANPNGGAGGFL
YGNGGNGFSQTTAGVAGGSGGAAGLIGNGGMGGAGGAGAAGGAGGTGGWWFGNGGVGGAGGAGTAGAVGF
NGVSGGAGGAGGAAGWWGAGGAGGQGGTGGMAGGYDNVNSVYGTTAGNGGDGGAGGRGGWLFGDAGAGGQ
GGLGGDGNYAGQGSYGGVGGAGGAGGAAGMFGSGGSGGAGGEGGAFGDGNAGGSGSGGHGGNGGNGGWLY
GDAGAGGQGGNAAPGAYSDNLGTIQYGNTSGNGGAGGNGGVAGMIGTGGAGGAGGAGGVNVYDSGGGGGG
GGTGGNGGWLYGNAGSGGQGGAGGDGSFLWDSPPNTNVYIGDAGGAGGVGGHGGSAGLIGSGGAGGAGGV
GGTGGYPAGNGGAGGDGGRAGLLFGSAGVGGQGGDGGGNYIAFTSNGNPNYNDGDAAGSGGAGGNGGAAG
LFGAGAAGGAGGAGGLSGYRSAGNGGAGGAGGAGGVLGGDGGAGGDGGAAGNGVNDPVTGAVEGDGGIGG
NGGTGGAALGWFGNGGAGGDGGAGGASQEFGDSGGNGGNGGAGGASGALIGAGGVGGSGGGGGAGVVGPP
AGNPGNDGLDGVTGASGLLFGG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_5321--100% (723)PE-PGRS family protein
M. marinum MMMAR_1208-0.055.14% (769) PE-PGRS family protein
M. marinum MMMAR_3316-0.054.82% (768) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1116PE_PGRS210.051.46% (785) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-13141.52% (778) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3388PE_PGRS520.053.68% (760) PE-PGRS family protein
M. leprae Br4923MLBr_01183-1e-1136.46% (96) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-2e-4635.56% (450) hypothetical protein MAB_4284c
M. avium 104MAV_4827-9e-2244.68% (141) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-11841.26% (715) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-4e-3935.57% (357) PUTATIVE -
M. ulcerans Agy99MUL_4399-0.086.05% (516) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-1e-12741.18% (760) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_5321|M.marinum_M               --------------------------------------------------
MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
Mb1116|M.bovis_AF2122/97            --------------------------------------------------
Rv3388|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_5321|M.marinum_M               --------------------------------------------------
MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
Mb1116|M.bovis_AF2122/97            --------------------------------------------------
Rv3388|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MMAR_5321|M.marinum_M               ------------------------------------------MSYLLVTP
MUL_4399|M.ulcerans_Agy99           ------------------------------------------MSYLLVAP
Mb1116|M.bovis_AF2122/97            ------------------------------------------MSFVVVAP
Rv3388|M.tuberculosis_H37Rv         ------------------------------------------MSFVIANP
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------------------MNIVLGVSMAP
                                                                                      

MMAR_5321|M.marinum_M               ----------------------------------------ELLTSAATDL
MUL_4399|M.ulcerans_Agy99           ----------------------------------------ELLTSAATDL
Mb1116|M.bovis_AF2122/97            ----------------------------------------EVLAAAASDL
Rv3388|M.tuberculosis_H37Rv         ----------------------------------------EMLAAAATDL
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------------------------------SSIQMVVLEG
                                                                                      

MMAR_5321|M.marinum_M               EG----------------------IASALS-----------TANLAAAVP
MUL_4399|M.ulcerans_Agy99           EG----------------------IASALS-----------TANLAAAVP
Mb1116|M.bovis_AF2122/97            AG----------------------IGSTLA-----------QANAAALAP
Rv3388|M.tuberculosis_H37Rv         AG----------------------IRSAIS-----------AATAAAAAP
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------EAALAN----------AGLSAVSAA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                EY---------------------------------------ADGATVEED
                                                                                      

MMAR_5321|M.marinum_M               TTG-------VLAAGADEVSAAVASLFAGYGQAYQSISLQANAFQAQFIQ
MUL_4399|M.ulcerans_Agy99           TTG-------MLAAGADEVSAAVASLFAGYGQAYQSISLQANAFQAQFIQ
Mb1116|M.bovis_AF2122/97            TTA-------VLAAGADEVSAAIASLFGAHGQAYQAVSAQMSAFHAQFMQ
Rv3388|M.tuberculosis_H37Rv         TIQ-------VAAAGADEVSLAISALFGQHAQAYQALSAQATIFHDQFVQ
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199      QVG-------AVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAA
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEA
                                                                                      

MMAR_5321|M.marinum_M               AINGAGGAYAAAEAASTSPLQAFEDTVLGVINAPTQTLLGRPLIGDGAAG
MUL_4399|M.ulcerans_Agy99           AINGAGGAYVAAEAASTSPLQAFEDTVLGVINAPTQTLLGRPLIGDGAAG
Mb1116|M.bovis_AF2122/97            ALTGAGGAYAAAEAVNVSAAQSVEQDLLAAINARFERIFGRPLIGDGANG
Rv3388|M.tuberculosis_H37Rv         ALTSGGNLYAAAES------HTVEQMVLNAINAPTQTLFGRPLIGDGANG
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu      GDGGSGGRTGLFSKLSRG--------------------------GDGGDG
MAB_4284c|M.abscessus_ATCC_199      QPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSF
MLBr_01183|M.leprae_Br4923          ----------------------------------------MPLFLNAEPQ
MAV_4827|M.avium_104                AALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTA
                                                                                      

MMAR_5321|M.marinum_M               TAANPNGGAGG--FLYGNGGNGFSQTTAGVAGGSG---------------
MUL_4399|M.ulcerans_Agy99           TVANPNGGAGG--FLYGNGGNGFSQTTAGVAGGAG---------------
Mb1116|M.bovis_AF2122/97            GPGQ-DGGPGG--LLYGNGGNGGTSTTVGMAGGNG---------------
Rv3388|M.tuberculosis_H37Rv         TAENPDGQNGG--LLFGNGGNGFTQTTAGVAGGNG---------------
Mflv_5091|M.gilvum_PYR-GCK          VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1       VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155      GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu      GLGGNGGHGGG-------TGIISLLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199      NRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNS---------------
MLBr_01183|M.leprae_Br4923          ALTAAANTLEG-----------LSAATVASNAAAA---------------
MAV_4827|M.avium_104                TLAVVETSDGS-----IPDVYKQQIRAESYGDAAG---------------
                                                                .     .               

MMAR_5321|M.marinum_M               -GAAGLIGNGGMGGAGG------AGAAGGAGGTGG--WWFGNGG------
MUL_4399|M.ulcerans_Agy99           -GAAGLIGNGGMGGAGG------AGAAGGAGGTGG--WWFGNGG------
Mb1116|M.bovis_AF2122/97            -GAAGLIGNGGFGGGGG------PGAAGGNGGAGG--WLFGNGG------
Rv3388|M.tuberculosis_H37Rv         -GSAGLIGNGGAGGGGG------AGAAGGLGGNGG--WLYGNGG------
Mflv_5091|M.gilvum_PYR-GCK          VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1       VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155      VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu      -NGYRTTDNNALDGGHG-----------GNGGNVG---FFSLFN------
MAB_4284c|M.abscessus_ATCC_199      GPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTN-----
MLBr_01183|M.leprae_Br4923          -QLTTEIAPPAADDVSI------------LLAHFF---------------
MAV_4827|M.avium_104                QLSAMVAGLEKLESLPG------GLLLVGSGVDVAP--------------
                                                 .                                    

MMAR_5321|M.marinum_M               -VGGAGG-----AGTA-GAVGFNGVSG-------GAGGAGGAAG----WW
MUL_4399|M.ulcerans_Agy99           -VGGAGG-----AGTA-GAVGFNGVSG-------GAGGAGGAAG----WW
Mb1116|M.bovis_AF2122/97            -AGGAGG-----LGVAPGVPGGAGGAG-------GAGGVGGPAG----LW
Rv3388|M.tuberculosis_H37Rv         -AGGIGG-----AGTGTGGHGGAGGAGGR-AWLWGTGGAGGAGGDGGWLF
Mflv_5091|M.gilvum_PYR-GCK          -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1       -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155      AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu      -LGGAGG------------WGGSGVDG--------VDVVGGNPD------
MAB_4284c|M.abscessus_ATCC_199      -VSGHGSADIDKSVTVVDDHSQRNTTNIN---DSFNTDRSTNIGSGNTTN
MLBr_01183|M.leprae_Br4923          --SGHGR-----------QYQAHASQG--------ATNHQDLIQS--LLT
MAV_4827|M.avium_104                -LKQVLQTTTFLDVSVAEEPETALARG--------AALAAANAPLFASST
                                                              .                       

MMAR_5321|M.marinum_M               GAGGAGGQGGTG----------------------GMAGGYDNVNSVYGT-
MUL_4399|M.ulcerans_Agy99           GAGGAGGQGGTG----------------------GMAGGYDNVNGVFGI-
Mb1116|M.bovis_AF2122/97            GHGGAGGAGGAGV---------------------AGAGGFEGTIGAGGAG
Rv3388|M.tuberculosis_H37Rv         GDGGAGGTGGNGGSGF--------NSLTSSVGGAGGAGGHAGLFGAGGTG
Mflv_5091|M.gilvum_PYR-GCK          ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1       ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155      TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu      --GGTPGAHGES----------------------HTPGVYTDRQGEDGED
MAB_4284c|M.abscessus_ATCC_199      TEIGSHNQANIG--------------------TSTSAGGSAAVGGNAGLA
MLBr_01183|M.leprae_Br4923          SSSAYAG---------------------------TETANHDSL-------
MAV_4827|M.avium_104                AALAYAQDPGTG-----------------------AVDQYSLPDYLYVPV
                                                                                      

MMAR_5321|M.marinum_M               -----------TAGNGG---------------------------------
MUL_4399|M.ulcerans_Agy99           -----------TAGNGG---------------------------------
Mb1116|M.bovis_AF2122/97            ----------GVGGAGG---------------------------------
Rv3388|M.tuberculosis_H37Rv         ----------GTGGIGGQNTET----------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1       ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155      SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu      -----------GTGTG----------------------------------
MAB_4284c|M.abscessus_ATCC_199      G----------NAGLAG---------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                DPEPGDDE------------------------------------------
                                                                                      

MMAR_5321|M.marinum_M               ---------DGGAGGRGG------------------------WLFGDAGA
MUL_4399|M.ulcerans_Agy99           ---------DGGAGGRGG------------------------WLFGDAGA
Mb1116|M.bovis_AF2122/97            ---------VGGAGGAGG------------------------WLYGDAGA
Rv3388|M.tuberculosis_H37Rv         -GPAASNGGAGGAGGGGG------------------------YLVGDGGA
Mflv_5091|M.gilvum_PYR-GCK          --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1       --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155      KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu      ---------IGGRGGNGG------------------------------SS
MAB_4284c|M.abscessus_ATCC_199      ---------NAGLAGNAG-------------------------LAGNAGL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------LAYSAVGEED-------------------------AESPTVV
                                                                                      

MMAR_5321|M.marinum_M               GGQGGLGGDG---------------------NYAGQGSY-----------
MUL_4399|M.ulcerans_Agy99           GGQGGLGGDG---------------------NYAGQGSY-----------
Mb1116|M.bovis_AF2122/97            GGDGGVGGAGGTGG---------------LGNRGGAGGA-----------
Rv3388|M.tuberculosis_H37Rv         GGTGGAGGKN---------------------SSGGATLT-----------
Mflv_5091|M.gilvum_PYR-GCK          GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1       GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu      SGTHPMAEDG----------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AGNAGLAGNAGLAG------------------NAGLAGN-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                IEKLFLPEDSEPRRR--------------PVLLVGSG-------------
                                                                                      

MMAR_5321|M.marinum_M               -----------GGVGGAGGAGGAAG-MFGSGGSGG---------------
MUL_4399|M.ulcerans_Agy99           -----------GGVGGAGGAGGAAG-MFGSGGSGG---------------
Mb1116|M.bovis_AF2122/97            -----------GGAGGVGGAGGAAG-LWGGGGAGG---------------
Rv3388|M.tuberculosis_H37Rv         -----------GGTGGTGGAGGAAGWLYGSGGAGG---------------
Mflv_5091|M.gilvum_PYR-GCK          -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155      AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
TH_3810|M.thermoresistible__bu      -----------EHVKALDGRPGLDG---GNGSHGG---------------
MAB_4284c|M.abscessus_ATCC_199      -----------AGLAGNAGLAGNAG-LAGNAGLAG---------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----------LAVVGISAVLALEIALAIGIRTTG---------------
                                                                                      

MMAR_5321|M.marinum_M               --AGGEGG----------------AFGDGNAGGSGSGGHGGNGGNGG--W
MUL_4399|M.ulcerans_Agy99           --AGGEGG----------------AFGDGNAGGSGSGGHGGNGGNGG--W
Mb1116|M.bovis_AF2122/97            --VGGTGGGAGLGAQSVTFSSSLSGLSGGDGGAGGAGGAGGAGGTGG--W
Rv3388|M.tuberculosis_H37Rv         --AGGAGG-----------------LNNAGGATGGTGGTGGAGGSGA--W
Mflv_5091|M.gilvum_PYR-GCK          --TGGTGGIGG------------AGSTGGTGGTGGTGGTGGTGGTG---G
Mvan_1264|M.vanbaalenii_PYR-1       --TGGTGGIGG------------AGSTGGTGGTGGTGGTGGTGGTG---G
MSMEG_0868|M.smegmatis_MC2_155      TDTGGNGGRGG------------DGGTFVNAGANGNGGAGGAGGVSE--G
TH_3810|M.thermoresistible__bu      --NGGHGG------------------RGGFLGIGGSGGWGGHGGNGG--D
MAB_4284c|M.abscessus_ATCC_199      --NAGLAGNAG---------------LAGNAGLAGNAGLAGNAGLAGNAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --TVALQPTPN---------------QHLIVPTEQAPAPPPVQASAPQPK
                                                                                      

MMAR_5321|M.marinum_M               LYGDAGAGGQGGNAAPGAYSDNLGTI----QYGNTSGNGGAGGNG-----
MUL_4399|M.ulcerans_Agy99           LYGDAGAGGQGGNAAPGAYSDNLGTF----QSSYTSGNGGAGGNG-----
Mb1116|M.bovis_AF2122/97            LYGGGGAAGSGGDGGTGGQGGAGGAG----VFSLFGSGGGPGGNG-----
Rv3388|M.tuberculosis_H37Rv         LYGNGGAAGAGGNGGNNTSAGTGG----------VGASGGTGGNA-----
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG-----
MSMEG_0868|M.smegmatis_MC2_155      EGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVD
TH_3810|M.thermoresistible__bu      TDADGGNGGDGGNGGSAGRGGTGGLR---------GVFGINGGNG-----
MAB_4284c|M.abscessus_ATCC_199      LAGNAGLAGNAGLAGNAGLAGNAAVAG----NAAVAGNAAVAGNA-----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ISVPEPVAAPKPLSPPVAAPLPAAPP--------PAAPPLPEAPP-----
                                                                                      

MMAR_5321|M.marinum_M               ----GVAGMIGTGGAG------------GAGGAGGVN------VYDSGGG
MUL_4399|M.ulcerans_Agy99           ----GVAGMIGTGGAG------------GAGGAGGVN------AFDSGGG
Mb1116|M.bovis_AF2122/97            ----GVGGVGGVGGAGG------RAGLFGVGGLGGAGG----DAGDSGEG
Rv3388|M.tuberculosis_H37Rv         ----GLIGAGGHGGAG------------GAGGNQTGG------VGNGGAG
Mflv_5091|M.gilvum_PYR-GCK          ----GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQG
Mvan_1264|M.vanbaalenii_PYR-1       ----GTGGTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQG
MSMEG_0868|M.smegmatis_MC2_155      PSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKG
TH_3810|M.thermoresistible__bu      -----RAGLGGRGXXX------------XGGGVGAAVR-----SGNGVFS
MAB_4284c|M.abscessus_ATCC_199      ----AVGGVLNTGVSG------------AIGGSSHVGG-----AINESLG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -----IPAAPPVVPVP-----------VVVPPVPVPVPVRIPVPDPVSPP
                                                                                      

MMAR_5321|M.marinum_M               GGGGGTG-------------------GNGGWLYGNAGSG-----------
MUL_4399|M.ulcerans_Agy99           GGGG----------------------------------------------
Mb1116|M.bovis_AF2122/97            GFGGP---------------------GLAGGLFGNPGNG-----------
Rv3388|M.tuberculosis_H37Rv         GNGGAG--------------------GAGGQLYGNGGDG-----------
Mflv_5091|M.gilvum_PYR-GCK          GQGG-----------------TGGTGGQGG-LGGGGGTG-----------
Mvan_1264|M.vanbaalenii_PYR-1       GQGG-----------------TGGTGGQGG-LGGVGGTG-----------
MSMEG_0868|M.smegmatis_MC2_155      GDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVV
TH_3810|M.thermoresistible__bu      GGGG----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GSGSVG--------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                QLLAPP--------------------------------------------
                                                                                      

MMAR_5321|M.marinum_M               ------------GQGGAGGDGSFLWDSPPNTNV-YI-GDAGGAGGVGGHG
MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
Mb1116|M.bovis_AF2122/97            ------------GVGGIGGDAAAGGAGGAGGNGGWL-FGNGGAGGSGGDG
Rv3388|M.tuberculosis_H37Rv         ------------GNGGAGGANIAGGNGS-----------DGGAAGHGGAG
Mflv_5091|M.gilvum_PYR-GCK          ------------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAG
Mvan_1264|M.vanbaalenii_PYR-1       ------------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAG
MSMEG_0868|M.smegmatis_MC2_155      QANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------GSTAVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------RLSVPQ
                                                                                      

MMAR_5321|M.marinum_M               GSAGLIGSGGAGGAGGVGG-TGGYPAGNGGAGGDGGRAGLLFGSA-GVGG
MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
Mb1116|M.bovis_AF2122/97            GAAGRGGAGNLGSAGGINA-PAGNPGSGSVGIGGAGGAGGTAGLF-GDGG
Rv3388|M.tuberculosis_H37Rv         GSARLIGAGGHGGDGGAGGNTAGRRADAIAGTGGDGGNGGNGGLLSGNAG
Mflv_5091|M.gilvum_PYR-GCK          GDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGL
Mvan_1264|M.vanbaalenii_PYR-1       GDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGL
MSMEG_0868|M.smegmatis_MC2_155      GDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNYGGGH
                                                                                      

MMAR_5321|M.marinum_M               QG----GDGGGNYIAFTSNGNPNYNDGDAAGSGGAGGNGGAAGLFGAGAA
MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
Mb1116|M.bovis_AF2122/97            AG----GAGAAG--GFGGISAATPSAGSEGAMGGAGGVGGNARLLGTGGA
Rv3388|M.tuberculosis_H37Rv         AG----GHGGAGGSSTATTTTGTPPTGATGGNGGNGGAGGTAGFTGSGGI
Mflv_5091|M.gilvum_PYR-GCK          FG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGAT
Mvan_1264|M.vanbaalenii_PYR-1       FG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGAT
MSMEG_0868|M.smegmatis_MC2_155      GGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GG-----VSTGVGVGSHVGGGISESLGGSGSVGGSTAVGG----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VP----TPGAGGSGGSGGGHVPTPGAGGSGGSGGGHVPTP----------
                                                                                      

MMAR_5321|M.marinum_M               GGAGGAGGLSGYRSAGNGGAGGAGGAGGVLGGDGG-----------AGGD
MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
Mb1116|M.bovis_AF2122/97            GGVGGGGGAGGDGGRGGVATPGGQGGDAGDGGAGG-----------AGGN
Rv3388|M.tuberculosis_H37Rv         GGNGGAGG-----------TGGNAGVALSVGSTGG-----------LGGN
Mflv_5091|M.gilvum_PYR-GCK          G-ATGAAGKAG--------ATGAAGAAGAAGSAG-----------TTGAQ
Mvan_1264|M.vanbaalenii_PYR-1       G-ATGASGAQG--------SAGSAGSAGVAGSAG-----------TTGAQ
MSMEG_0868|M.smegmatis_MC2_155      GVATGNTATGG--------DGGAATTAGATGGAGGFSNIAAIHGAITDST
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------------------GAH
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------------------------------GT
                                                                                      

MMAR_5321|M.marinum_M               GGAAGNGVNDPVTGAVEGDGGIGGNGGTGGAA--------LGWFGNGGAG
MUL_4399|M.ulcerans_Agy99           --------------------------------------------------
Mb1116|M.bovis_AF2122/97            GGGGASGAGGWLLG-TGGAGGAGGNGGNGGKAGFSPGPTNFGLNGAGGGG
Rv3388|M.tuberculosis_H37Rv         GGSGGLGGGGGSLFGNGGAGGVGATGGNGGSG--------IGPASVGGNG
Mflv_5091|M.gilvum_PYR-GCK          GSAGTNGA-NGANGSQGAAGKAGATGTTGATG-------------AAGED
Mvan_1264|M.vanbaalenii_PYR-1       GSAGTNGA-NGANGSQGAAGKAGATGTTGATG-------------AAGDA
MSMEG_0868|M.smegmatis_MC2_155      AISGHGGAGNGGNGGKGADGWVQAYDPAGPVGS-----KIANSSAVAGNG
TH_3810|M.thermoresistible__bu      -------------------------------------------------T
MAB_4284c|M.abscessus_ATCC_199      TGVGGGVNTGVGVGSHVGGGISESLGGSGSVGG------------STAVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GGPGGTGGSGGGHVPTPGAGTPGGSGGGHLPFP-------------GAGS
                                                                                      

MMAR_5321|M.marinum_M               GDGGAGGASQEFGDSGGNGGN-----------------GGAGGASG----
MUL_4399|M.ulcerans_Agy99           ----------------GNGGN-----------------GGAGGASG----
Mb1116|M.bovis_AF2122/97            GVGGNGATGPWLFGDGGAGGG-----------------GGAGGIGGDGGP
Rv3388|M.tuberculosis_H37Rv         GKGGVGAAGG-LAGQIGNGGS-----------------GGSGGAGG----
Mflv_5091|M.gilvum_PYR-GCK          GDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE
Mvan_1264|M.vanbaalenii_PYR-1       GDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE
MSMEG_0868|M.smegmatis_MC2_155      GDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSE
TH_3810|M.thermoresistible__bu      PSAGFGVPTTIQFPAGSCTSR-----------------------------
MAB_4284c|M.abscessus_ATCC_199      GGAHTSAINDALGGSGSVGGS-----------------TAVGGGAHTSAI
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                TPGGSGGGHLPTPGAGTPGG-------------------GLGGFGG----
                                                                                      

MMAR_5321|M.marinum_M               ------ALIGAGGVGGSGGGG---GAGVVGPPAGNPGNDGLDGVTGASGL
MUL_4399|M.ulcerans_Agy99           ------ALIEAGGVGGSGGGG---GAGVVGPPAGNPGNDGLDGVTGASGL
Mb1116|M.bovis_AF2122/97            T----PGSTGAGAAGGHGGDAQLIGNGGHGGAGGTGVPNGSGGAGGLSGL
Rv3388|M.tuberculosis_H37Rv         -------NGGTGDTAGNGGNG---GAGAVGGNAQLIGNGGNGGGGGNGGT
Mflv_5091|M.gilvum_PYR-GCK          --------GGAGGGGGAGGSG--AGGAG--GAGGSGGSGGSGGSGGSGGA
Mvan_1264|M.vanbaalenii_PYR-1       --------GGAGGSGGAGGSG--TGGAG--GAGGSGGSGGSGGAGGSGGA
MSMEG_0868|M.smegmatis_MC2_155      PGPGGNGAGGAGGNGGTGGTT--AGGSGNGGNGGNGGNGGADGTPGTAGT
TH_3810|M.thermoresistible__bu      ---------AVSREGIMPSSR---AASARAGAACASSTSRSRRSFCCSRA
MAB_4284c|M.abscessus_ATCC_199      NESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHT
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------GHAPAPGGGLGGG---GGHAPAPGGGLGGFGGGHSGGGLGGL
                                                                                      

MMAR_5321|M.marinum_M               LFGG-----
MUL_4399|M.ulcerans_Agy99           LFGG-----
Mb1116|M.bovis_AF2122/97            LFGEPGANG
Rv3388|M.tuberculosis_H37Rv         GADGT----
Mflv_5091|M.gilvum_PYR-GCK          AGDSDD---
Mvan_1264|M.vanbaalenii_PYR-1       AGDSD----
MSMEG_0868|M.smegmatis_MC2_155      TGANNP---
TH_3810|M.thermoresistible__bu      ---------
MAB_4284c|M.abscessus_ATCC_199      TLPGAEHH-
MLBr_01183|M.leprae_Br4923          ---------
MAV_4827|M.avium_104                GGGHK----