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MSYVLVTPEMVATAAADAAAIGSTVSAANAAAAIPTTAIATAAADDVSAAIAALFNAHAEQYQALSVRVA ELHESFTRALTAGSTAYATAEAANAGPLQPLLDLINAPTQALLARPLIGDGSNGAPGTGQAGGNGGLLIG NGGAGGSGAPGQRGGAGGAGGLLLGNGGAGGAGGVGALGQASGTGGNGGAGGLLFGKGGAGGAGGVGGLG QAGGTGGNGGAGGLLFGNGGAGGVGGAGGVGGVDSAGGTGGTGGTGGANGLFGAAGSGGSGGAGGDGAPG DTAGAGGTGGTGSAGGAGGTGGAGGANQFFGHAGDGGHGGTGGTGGTGGAGGSGVGSGLAGGAGGDGGAG GAAGRGGAAGAGGPLVTPGHAGNTGTGGTGGTGGTGGNGDLHTNGGNGGTGGSGGAGIAGVGGGNGGTGG DGGKGGTGANGAPLGASGGTGGDGGKGGGGGNATDGGHGGNGGTGGTAGDGGNGQSGDLNANGGGGGRGG TGGAGGIGGTTTGGGDAGAGGGGGAGGTGGSGGEGGAGGFGGDGGAGGTGGKAGAGGDGGNATDGGNAGA GGDGGTGGAGGTGGGIVTGINGGAGGAGGDGGDSGNGGNATGGGNGGNGGTAGTGGAGGLGGGGFRVGHG GGGGNGGNGGVGGTATAGGDAGSGGTGGVGGDGSVGGDASDAVAGGDGGTGGRGGSGGAGGIATGGGSAG HGGVGGGGGNGGHGTDGTAGVAGHGGGAGGAGGDAGDGGKGGDALDGGTAGAGGAGGKAGNGGGAGSGGK GTFDGGAGGAGGDGGKAGNGGAGGIDSNGQVADGGDGGDGGNGGDGGNGGDGSPVGAGGTGGIGTAGGAG GGGGAVSGRPGQNGSEGQPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3758 | - | - | 100% (860) | PE-PGRS family protein |
| M. marinum M | MMAR_2033 | - | 0.0 | 53.81% (957) | PE-PGRS family protein |
| M. marinum M | MMAR_4995 | - | 0.0 | 52.87% (974) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3543 | PE_PGRS57 | 0.0 | 52.14% (1007) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 49.80% (755) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3507 | PE_PGRS53 | 0.0 | 52.40% (981) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-11 | 41.38% (87) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-55 | 31.10% (553) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 1e-25 | 42.25% (187) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-157 | 38.65% (1115) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-45 | 41.33% (300) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 48.63% (1024) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 0.0 | 50.45% (785) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3758|M.marinum_M --------------------------------------------------
Rv3507|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------MMFLAPPGGPGPISAAIQLTS
MMAR_3758|M.marinum_M -----------------------------MSYVL-VTPEMVATAAADAAA
Rv3507|M.tuberculosis_H37Rv -----------------------------MSFVL-VSPETVAAVATDLKR
MLBr_01183|M.leprae_Br4923 -----------------------------MPLFLNAEPQALTAAANTLEG
Mb3543|M.bovis_AF2122/97 -----------------------------MSFVL-IAPEFVTAAAGDLTN
MUL_4367|M.ulcerans_Agy99 -----------------------------MSFVS-VGPGLLEAAARDLAG
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------MSIIDFILNLFRDPVEAASY
MAV_4827|M.avium_104 -----------------------------MNIVLGVSMAPSSIQMVVLEG
Mflv_5091|M.gilvum_PYR-GCK ----------MVTFGGGATPTPTSLGAAAVDLSGTSCGLICNGQDGTGQN
Mvan_1264|M.vanbaalenii_PYR-1 TGSEATEPWYVVSFGGSGAPTPNNLAASLVDLSGTSCGLICNGQDGTGQN
MMAR_3758|M.marinum_M IGST------VSAANAAAAIPTTAIATAAADDVSAAIAALFNAHAEQYQA
Rv3507|M.tuberculosis_H37Rv IGAS------LAHENASAAASTTAVVSAAADEVSTAVAALFSQHAQGYQA
MLBr_01183|M.leprae_Br4923 LSAA------TVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQA
Mb3543|M.bovis_AF2122/97 LGSS------ISAANASAASATTQVLAAGADEVSARIAALFGGFGLEYQA
MUL_4367|M.ulcerans_Agy99 LGAG------LREANLAAAGATVGVLPAAGDEVSAAIAELFGGFGREYQA
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGDGGDGG
MAB_4284c|M.abscessus_ATCC_199 VADP------EAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVN
MAV_4827|M.avium_104 EYADG-------ATVEEDAIDVTGADDAATASAPDRVISAILGTREGAAD
Mflv_5091|M.gilvum_PYR-GCK GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGN--------------
Mvan_1264|M.vanbaalenii_PYR-1 GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGN--------------
MMAR_3758|M.marinum_M LSVRVAELHESFTRALTAGSTAYATAEAANAGPLQP----LLDLINAPTQ
Rv3507|M.tuberculosis_H37Rv AAAQVAAFHSRFVQALTAGAGAYAFAEAANASPLQS----AMGAVSASAQ
MLBr_01183|M.leprae_Br4923 HASQGATNHQDLIQSLLTSSSAYAGTETANHDSL----------------
Mb3543|M.bovis_AF2122/97 ISAQVAAYHQRFVQALSTGAGAYASAEAAAAEQIV------LGVINAPTQ
MUL_4367|M.ulcerans_Agy99 MGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQELEQQALGVVNAPSM
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu LGGNGGHGGGTGIISLLSLAGNGGNGGNGYRTTDNN--------------
MAB_4284c|M.abscessus_ATCC_199 TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDN--------------
MAV_4827|M.avium_104 AGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVS-------------
.
Mflv_5091|M.gilvum_PYR-GCK -------------------------------GGNGLGGGNGGNGGNAGAF
Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------GGNGLGSGDGGNGGDAGLF
MMAR_3758|M.marinum_M ALLARPLIGDGS---------------------NGAPG-TGQAGGNGG--
Rv3507|M.tuberculosis_H37Rv TLLSRPLIGNGANATT-PGGNGGDGGWLFGSGGNGAPGAAGQSGGNGGSA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 ALLGRPLIGDGANATT-PGGAGGAGGLLFGNGGAGAAGAPGQAGGPGGPA
MUL_4367|M.ulcerans_Agy99 ALFGRPSIGNGVDGVAGTGQAGGAGGILWGNGGNGGLGAAGANGGAGGSA
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAG---QQFWVVSPIGSTLGGVINTISGQYLIGNGIN
TH_3810|M.thermoresistible__bu ----------------------------------ALDGGHGGNGGNVGFF
MAB_4284c|M.abscessus_ATCC_199 -----------------------------DFLSHNDTDFASHNPIASGNQ
MAV_4827|M.avium_104 ----------------------------AFLAAAALAQNVGGAMGYERTA
Mflv_5091|M.gilvum_PYR-GCK ALFGNGGNGGNGGVGVVGATGAVGAPGVAGATGATGVTSGVVGGNGEDAV
Mvan_1264|M.vanbaalenii_PYR-1 SLFGRGGNGGNGGVGIAGATGAVGAPGVAGATGATGVTSNVTGGNGADAV
MMAR_3758|M.marinum_M LLIGNGGAGGSG-----APG-QRGGAGGAGGLLLGNGGAGGAGGVGALGQ
Rv3507|M.tuberculosis_H37Rv GLWGNGGAGGAG-----GSGGAAGGNGGNGGWLFGAGGTGGIGGTGAPGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GLWGNGGPGGAG-----GSGGGTGGAGGAGGWLFGVGGAGGVG-----GA
MUL_4367|M.ulcerans_Agy99 GLIGTGGVGGAGGVGAAGMTGGSGGAGGGGGWLWGAGGS---------GG
MSMEG_0868|M.smegmatis_MC2_155 GTADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGW
TH_3810|M.thermoresistible__bu SLFNLGGAGGWG--------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VMSPSGNVDSFN--------RGPLLDLSFGDLQFGNRDTTAIG------D
MAV_4827|M.avium_104 VLLVEPDTATLA-----VVETSDGSIPDVYKQQIRAESYGDAAGQLSAMV
Mflv_5091|M.gilvum_PYR-GCK GYGATGAAGAAGAAGAAGAAGAVGSAGAAG--EAGETGTWGNAGLPGKAG
Mvan_1264|M.vanbaalenii_PYR-1 GYGATGAAGAAGAAGAAGKAGAVGSAGTAG--SAGAPGVWGNAGLPGAAG
MMAR_3758|M.marinum_M ASGTGGNGGAGGLLFGKGGAGGAGGVGGLG-QAGGTGGNGGAGGLLFGNG
Rv3507|M.tuberculosis_H37Rv MGGTGGNGGNGALLIGGGGLGGAGGMGGTGGGTGGTGGNGGNGALLIGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GGGTGGAGGPGGLIWGGGGAGGVGGAG------GGTGGAGGRAELLFGAG
MUL_4367|M.ulcerans_Agy99 AAGAGGSGGSGGWLWGNAGQTAGAGVGG----AGGAGGAGDAGDQGVSGV
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu -----GSGVDGVDVVGGNPD-------------GGTPGAHGESHTPGVYT
MAB_4284c|M.abscessus_ATCC_199 GAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVG
MAV_4827|M.avium_104 AGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALARG
Mflv_5091|M.gilvum_PYR-GCK DAGGAGAVGAAG-----AAGTVGTAGATGGTGTGANGGAGGVGGVGG---
Mvan_1264|M.vanbaalenii_PYR-1 AAGGAGAIGTAG-----VAGAAGTAGATGGTGVGGNGGAGQAGGIGG---
MMAR_3758|M.marinum_M GAGGVGGAGGVG-GVDSAGGTGGTGGTGGANGLFGAAGSGGSGGAGG---
Rv3507|M.tuberculosis_H37Rv GVGGAGGIGGQGTGAGGAAGAGGTGGNGGAGGLFMNGGDGGAGGQGG---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GAGGAGGAGTDG-GPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGG---
MUL_4367|M.ulcerans_Agy99 APGEAGAVGFAG-GAGGAGGAGGNGVGGGVNGAGGAGGAGGVGGGGG---
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu DRQGEDGEDGTG---TGIGGRGGNGGSSSGTHPMAEDGEHVKALDGR---
MAB_4284c|M.abscessus_ATCC_199 G-DYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGS---
MAV_4827|M.avium_104 AALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPGD--
Mflv_5091|M.gilvum_PYR-GCK -TGAAG-AAGGAGGLGETGTTGGAGGVGGQGTAG----GTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 -TGAAG-AAGQAGTAGETGVTGGVGGIGGQGTEG----GTGGVGGVGGVG
MMAR_3758|M.marinum_M -DGAPGDTAG-AGGTGGTGSAGGAGGTGGAGGAN-QFFGHAGDGGHGGTG
Rv3507|M.tuberculosis_H37Rv -DGAAGDAAASAGGTGGKGGQGGDGGTGGAGGAGPVLFGHGGAGGMGGQG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 -AGGAGSDGGALGGTGGTG---GTGGAGGAGGRGALLLGAGGQGGLGGAG
MUL_4367|M.ulcerans_Agy99 -AGASGVGAGVAGGDGGTGGAGGAAGVGGAAGTG----GTGGAAGVAGTG
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu -----------PGLDGGNGSHGGNGG-------------HGGRGGFLGIG
MAB_4284c|M.abscessus_ATCC_199 -----GNTTNTEIGSHNQANIGTSTSAGGSAAVG----GNAGLAGNAGLA
MAV_4827|M.avium_104 -DELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVGIS
Mflv_5091|M.gilvum_PYR-GCK STGAVGGVGGKGIQGGQGLQ-------GGKGGDGGAGGKGGDADSMGSAG
Mvan_1264|M.vanbaalenii_PYR-1 ATGGAGGVGGKGIQGGQGLQ-------GGQGGDGGTGGTGGDATSMGEAG
MMAR_3758|M.marinum_M GTGGTGGAGGSGVGSGLAGG------AGGDGGAGGAAGRGGAAGAGGPLV
Rv3507|M.tuberculosis_H37Rv GTGGMGGAGGDGT-TVIAAG------TGGEGGTGGAAGAGGAAGARGALT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GQGGMGGAGGAGADNPTGIGG-----TGGDGGTGGSAGEGGAGGAAGQLF
MUL_4367|M.ulcerans_Agy99 GDGGDGGAGGAGSDASLAGQAGFAGGSGGAGGVGGSAGAGGVNGSGGDGG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu GSGGWGGHGGNGGDTDADGGN------GGDGGNGGSAGRGGTGGLRG---
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAGN-------AGLAGNAGLAGNAGLAGNAG---
MAV_4827|M.avium_104 AVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQ--
Mflv_5091|M.gilvum_PYR-GCK ATGGKGGNGGNGGRGGLFGKGGN---------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ATGGKGGNGGNGGRGSLFGRGGN---------------------------
MMAR_3758|M.marinum_M TP-GHAGNTGTGGTGGTGGTGGN---------------------------
Rv3507|M.tuberculosis_H37Rv SG-GLAGGVGAGGTGGTGGTGGNGADAAAVVGFGANGDPGFAGGKGGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 SASGAAGNAGVGGAGGQGGDGGAGGAGADADQPGATGGTGFAGGAGGAGG
MUL_4367|M.ulcerans_Agy99 AGAAGGAGGASATVAGSGGVGGDGGAGGAAGGGVGAASLGGDGGHAGAGG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------AGNGADGGTGGAGGAGG-----------------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------AGNGGNGGTGGNGGNGG-----------------------
MMAR_3758|M.marinum_M -------GDLHTNGGNGGTGGSGGAG--------------------IAGV
Rv3507|M.tuberculosis_H37Rv IGGAAVTGGVAGDGGTGGKGGTGGAGGAGNDAGSTGNPGGKGGDGGIGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 AGGSSGAGGTNGSGGAGGTGGQGGMGG-------------------AGGA
MUL_4367|M.ulcerans_Agy99 AGGEGLSGGFN-TGAAGGIGGAGGAGG-------------------TGGD
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGG-------------------RGGT
TH_3810|M.thermoresistible__bu ---------VFGINGGNGRAGLGGRGX-----------------------
MAB_4284c|M.abscessus_ATCC_199 ---------LAGNAGLAGNAGLAGNAG-----------------------
MAV_4827|M.avium_104 ----------PKISVPEPVAAPKPLSP-----------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------TGGTGGAGGTG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------TGGTGGNGGTG-----------------
MMAR_3758|M.marinum_M G-------------------GGNGGTGGDGGKGGTGANGAP---------
Rv3507|M.tuberculosis_H37Rv GGAGGAAGTGNGGHAGNTGDGGDGGTGGNGGNGTGGVNGADNTLNPDTPG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 G---------------ADNPTGIGGTGGDGGTGGAAG-------------
MUL_4367|M.ulcerans_Agy99 S-------------------GGVGGVNGDGGAGGGGGRGGD---------
MSMEG_0868|M.smegmatis_MC2_155 SWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGD------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------------GTGGTGGIGGAGSTGGTGG-TGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 -------------------GTGGTGGIGGAGSTGGTGG-TGGTGGTGGTG
MMAR_3758|M.marinum_M -----------LGASGGTGGDGGKGGGGGNATDGGHGG-NGGTGGTAGDG
Rv3507|M.tuberculosis_H37Rv GAGEPGGAGGAGGAGGAAGGPGGTGGTGGNGGNGGNGG-NGGNGGNGGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 -----------AGGAGGAAGTGGTGGMIGTTGNAGVGG-AGGQGGDGGAG
MUL_4367|M.ulcerans_Agy99 -----------GGSSTSTSGVGGAGGAGGNGGNAGFGVSAGGTGGSAGDG
MSMEG_0868|M.smegmatis_MC2_155 ---------ALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIA
TH_3810|M.thermoresistible__bu ---------------------XXXGGGVGAAVRSGNGVFSGGGGTPSAGF
MAB_4284c|M.abscessus_ATCC_199 --------------------LAGNAGLAGNAGLAGNAG-LAGNAGLAGNA
MAV_4827|M.avium_104 ----------------------PVAAPLPAAPPPAAPPLPEAPPIPAAPP
Mflv_5091|M.gilvum_PYR-GCK GTGG-------TGGTGGTGGTGGKGGTGG----------------TGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GTGG-------TGGTGGTGGTGGKGGTGG----------------TGGDG
MMAR_3758|M.marinum_M GNGQSGDLNANGGG-GGRGGTGGAGGIGG--TTTG-----------GGDA
Rv3507|M.tuberculosis_H37Rv GNAGNNSTNAPVGGEGGAGGDGGAGGAGG--AANGGTAGSQGTGGVGGDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GAGADADQPGATGGTGFAGGAGGAGGAGGS-SGAGGTNGSGGAGGTGGQG
MUL_4367|M.ulcerans_Agy99 GAGGGAGGVDGVGGASGNGGAAGAGGAGGSGIGAGIDGGAGGAGGTGGAA
MSMEG_0868|M.smegmatis_MC2_155 AIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKA
TH_3810|M.thermoresistible__bu GVPTTIQFPAGSCTSRAVSREGIMP-------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAGNAGLAGN---------------------
MAV_4827|M.avium_104 VVPVPVVVPPVPVPVPVRIPVPDPVSPPQ---------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGDGGTG---------------------------------------GT
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTG---------------------------------------GT
MMAR_3758|M.marinum_M GAGGGGGAG---------------------------------------GT
Rv3507|M.tuberculosis_H37Rv GAGGNGGGGKAGTGNSGNFGVDGEAGFSGGAGGNGGVGGAAGANGGTGGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GAGGAGGAG-------------------------------------ADNP
MUL_4367|M.ulcerans_Agy99 GFPGGGGTTG------------------------------------AWGT
MSMEG_0868|M.smegmatis_MC2_155 AGGNGGDGGFN-------------------------------------GT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGTG----------------------------GTGGAGDGT
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGTG----------------------------GTGGAGDGL
MMAR_3758|M.marinum_M GGSGGEGGAGGFG-------------------------GDGGAGGTGGKA
Rv3507|M.tuberculosis_H37Rv GGNGGDGGAGGIGGAGGNGIPGTGTEPAGGTGAKGGDGGDGGAGGAGGNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 TGIGGTGGDGGTG-------------------------GAAGAGGAGGAA
MUL_4367|M.ulcerans_Agy99 GGAGGAGGAGGAGDHGG----------------VGVNPGDSGTAGWAGGA
MSMEG_0868|M.smegmatis_MC2_155 GGATGGRGGDGAGASVWKANG-----------QHSTGQTDTGGNGGRGGD
TH_3810|M.thermoresistible__bu ---------------------------------------SSRAASARAGA
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------------AAV
MAV_4827|M.avium_104 ----------------------------------------LLAPPRLSVP
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGQGGQGGQG----------------------GTGGTGGQG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGFGGQGGQG----------------------GTGGTGGQG
MMAR_3758|M.marinum_M G-AGGDGGNATDGGNAGAG----------------------GDGGTGGAG
Rv3507|M.tuberculosis_H37Rv GGAGGQGGNAGQGGAGGAGGNAVIPGDGVGKAPHGDAGGSGGDGGKGGQG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 G-TGGTGGMIGTTGNAGVG----------------------GAGGQGGDG
MUL_4367|M.ulcerans_Agy99 GGAGGAGGSAAFNGVNGAGG--------------------AGGNGGAGGG
MSMEG_0868|M.smegmatis_MC2_155 GGTFVNAGANGNGGAGGAGG------------------VSEGEGGTGGHG
TH_3810|M.thermoresistible__bu ACASSTSRSRRSFCCSRA--------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAAVAGNAAVAGNAAVG----------------------GVLNTGVSG
MAV_4827|M.avium_104 QPVQPPVRVPQPPSPPQVG-------------------------GTVPQS
Mflv_5091|M.gilvum_PYR-GCK GLGGGGGTGG--QGGTGGTGGQG---------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GLGGVGGTGG--TGGTGGTGGQG---------------------------
MMAR_3758|M.marinum_M GTG--GGIVTGINGGAGGAGGDG---------------------------
Rv3507|M.tuberculosis_H37Rv GSGGTGGSGAPIGGGAGGTGGSGGHAGKGGAGGIGAQGTTITVPGNGGNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GAGGAGGAGG--SSGAGGTNGSG---------------------------
MUL_4367|M.ulcerans_Agy99 GGAGASGIGAGVAGGDGGTGGTG---------------------------
MSMEG_0868|M.smegmatis_MC2_155 GDGGRGGDGA--LGGNGGTGGVG--------------------------L
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AIGGSSHVGGAINESLGGSGSVG---------------------------
MAV_4827|M.avium_104 PPQHQTPPGEGTPPKPDGPGNYG---------------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTGGTGGAG-----------------------GDGGLGGLG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTGGTGGAG-----------------------GDGGLGGLG
MMAR_3758|M.marinum_M GDSGNGGNATGGGNGGNG--------------------GTAGTGGAGGLG
Rv3507|M.tuberculosis_H37Rv GDGGNGGNAGAGGNGGSGDFGGNTTSGASGSGGNGGNAGTAGSGGAGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GAGGTGGQGGAGGAGGAG------------------ADNPTGIGGTGGDG
MUL_4367|M.ulcerans_Agy99 GAAGTGGAAGTGGTGGAAG-----------------AAGSAGDGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 GNGGKGGNGGNGGNGGTYVDP--------------SHTGAGGNGGNGGAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSTAVGGGAHTGVGGGVS-----------------------TGVGVGSHV
MAV_4827|M.avium_104 --GGHVPTPGAGGSGGSG-------------------------------G
Mflv_5091|M.gilvum_PYR-GCK GFGGSGGTGGQGGLGGPGGSTG----------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GFGGVGGTGGQGGQGGPGGSTG----------------------------
MMAR_3758|M.marinum_M GGGFRVGHGGGGGNGGNGGVGG----------------------------
Rv3507|M.tuberculosis_H37Rv GTGLSGGNGGNGGNGGNGGDGGNGAHGTVGAQFVPATSLPTPNGGAGGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GTGGAAGAGGAGGAAGTGGTGG----------------------------
MUL_4367|M.ulcerans_Agy99 GAGDDGSAGVVSGDPGTAGKAG----------------------------
MSMEG_0868|M.smegmatis_MC2_155 RIRVNNGTATGTATGGNGGNGGNGDADG----------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVGGSTAVGG----------------------------
MAV_4827|M.avium_104 GHVPTPGAGGSGGSGGGHVPTP----------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------------------------GAGGAGGQAGTAGKG------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------GAGGAGGQAGVAGKG------
MMAR_3758|M.marinum_M ---------------TATAGGDAGS---GGTGGVGGDGSVGGDASDAV--
Rv3507|M.tuberculosis_H37Rv GTGSNGGAPGPAGAPGPTTGGNAGSQGIGGDGGNGGDGGKGGDGADAVNV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 ------------------MIGTTGNAGVGGAGGQGGDGGAGGAGADADQ-
MUL_4367|M.ulcerans_Agy99 -----------GAGGAGGVGGNGVAGGVNGSGGAGGAGGAGGTGGAGASG
MSMEG_0868|M.smegmatis_MC2_155 HRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATI
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------GAHTGVGGGVSTGVGVGSHVG-
MAV_4827|M.avium_104 -----------------------------GTGGPGGTGGS----------
Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------------GLFGG
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------------------GLFGG
MMAR_3758|M.marinum_M -----------------------------------------------AGG
Rv3507|M.tuberculosis_H37Rv VFMPTEPQAATGTAGSAGDPTGGNGGPGTPGSPMVAPPPPTPITQVQQGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 --------------------------------------------PGATGG
MUL_4367|M.ulcerans_Agy99 ------------------------------------------VPASVDGG
MSMEG_0868|M.smegmatis_MC2_155 VAYNVVQANPQASG----------------------------TATDGHGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------GGISES
MAV_4827|M.avium_104 -----------------------------------------------GGG
Mflv_5091|M.gilvum_PYR-GCK SGSAGKAGATGAAGASGGKGAQG---------ATGAQGATG---------
Mvan_1264|M.vanbaalenii_PYR-1 SGSAGTAGVTGASGASGGKGAQG---------ATGAQGATG---------
MMAR_3758|M.marinum_M DGGTGGRGGSGGAGGIATGG------------GSAGHGGVG---------
Rv3507|M.tuberculosis_H37Rv DGGAGGTGSTNANDGTATGGKGGEGGVGSILGGPGGNGGTGGNASATGTN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 TGFAGGAGGAGGAGGSSGAGG---------TNGSGGAGGTG---------
MUL_4367|M.ulcerans_Agy99 DGGAGGAGGAAGTGGSGGSAG---------NTGAGGAGGAG---------
MSMEG_0868|M.smegmatis_MC2_155 SGINGGHGGNGGQGTIEANGPSAVASG----IGAGGNGGDGIDG------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LGGSGSVGGSTAVGGGAHTG-----------VGGGVNTGVG---------
MAV_4827|M.avium_104 HVPTPGAGTPGGSGG-----------------GHLPFPGAG---------
Mflv_5091|M.gilvum_PYR-GCK -----------------AQGATGATGAAGKAGATGAAG-AAGAAGS----
Mvan_1264|M.vanbaalenii_PYR-1 -----------------AQGATGATGASGAQGSAGSAG-SAGVAGS----
MMAR_3758|M.marinum_M -----------------GGGGNGGHG---TDGTAGVAG-HGGGAGG----
Rv3507|M.tuberculosis_H37Rv GVANAGNGGKGGDGGQFGAGGNGGAGGSVTDGSAGSTA-GNGGNGGNATN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 -----------------GQGGAGGAGISFSNGSNGGTG-GTGGVGGTGGD
MUL_4367|M.ulcerans_Agy99 -----------------GAGGSAASTGVNGDGGAGGAG-GVGGLGGDSAA
MSMEG_0868|M.smegmatis_MC2_155 -----------------GLGGNGGDGVVNTTANAANPGSATGTATGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------VGSHVGGGISESLGGSGSVG------------
MAV_4827|M.avium_104 ------------------STPGGSGGGHLPTPGAGTPG------------
Mflv_5091|M.gilvum_PYR-GCK -------AGTTGAQGSAGTNGANGANGSQGAAGKAGATGTT---------
Mvan_1264|M.vanbaalenii_PYR-1 -------AGTTGAQGSAGTNGANGANGSQGAAGKAGATGTT---------
MMAR_3758|M.marinum_M -------AGGDAGDGGKGGD-----------ALDGGTAGAG---------
Rv3507|M.tuberculosis_H37Rv GTIAGQPAGGNGSAGGKGGDGGNIAAGATGTAGNGGNGGNGNDGA--VNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GGNAGTGAGDPGKGGTGGTGGSGGAGGSGGANFNGGTGGTGGTG------
MUL_4367|M.ulcerans_Agy99 TAGGGGAGGDGGKGGAGGAGVNGVGGGDGGKGGTGGAGGAGGAGSDGIIP
MSMEG_0868|M.smegmatis_MC2_155 KATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------GSTAVGGGAHTSAINDALGGSGSVGGSTAVGGG---------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGAAGEDGDAGSGGSGINGGAGGAGGAGGEGGEGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 GATGAAGDAGDPGSEAVDINGGAGGAGGAGGEGGEGG-------------
MMAR_3758|M.marinum_M GAGGKAGNGGGAGSGG--KGTFDGGAGGAGGDGGKAG-------------
Rv3507|M.tuberculosis_H37Rv GTGGSGGNGGNAGGGG--ANGGDGGAGGAGGAGGRGGKGIDGGFGGDGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GTGGKGGMGGIAGDGG--PGG-DGGNAGVGGKGGTNG-------------
MUL_4367|M.ulcerans_Agy99 SNGGLGGNGGNGGNGGQAFGDGVGGAGGIGGKGGNAAIG-----------
MSMEG_0868|M.smegmatis_MC2_155 GNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAIT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAG-------------
MAV_4827|M.avium_104 --------GGLGGFGGGHAPAPGGGLGGGGGHAPAPG-------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------DGGKGG
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------AGGAGG
MMAR_3758|M.marinum_M --------------NGGAGGIDSN-------------------GQVADGG
Rv3507|M.tuberculosis_H37Rv GGSNNGTGAGGNGGNGGTGGVGSVGAAGGDGGNGGTGGFAGFGGTAGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 --------------NGGSGGTGGTGGPGGSGGAPTGSGTGGKGGAGGDGG
MUL_4367|M.ulcerans_Agy99 ----------TIVINGGVGGAGGSGGLGG-ATEDGVGGVGCAGGAGGNGG
MSMEG_0868|M.smegmatis_MC2_155 DSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AG-------AEGGAGGGGGAGGSGAG----GAGGAGGSGGSGGSGGSG--
Mvan_1264|M.vanbaalenii_PYR-1 DG-------SEGGAGGSGGAGGSGTG----GAGGAGGSGGSGGSGGAG--
MMAR_3758|M.marinum_M DG-------GDGGNGGDGGNGGDGSP---VGAGGTGGIGTAGGAGGGG--
Rv3507|M.tuberculosis_H37Rv SG-------GTGGAGGDGGTGGDGGNGVIAGGGGTGGNGGASGAGGAGGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 DG-------ADGGAATGVGDGGDGGNGGNGGNGGTG-VGSPGGLGGAGGT
MUL_4367|M.ulcerans_Agy99 RGDMLFTVGGSGGTGGDGGGGGSASGSGTGGSGGTGGVGGIGGDGKLGGF
MSMEG_0868|M.smegmatis_MC2_155 GGVN----GTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------TGFEAQGHAQGHASETAHTTLPGAEHH------------
MAV_4827|M.avium_104 --------------GGLGGFGGGHSGGGLGGLGGGHK-------------
Mflv_5091|M.gilvum_PYR-GCK ------------------------------GSGGAAGDSDD---------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------GSGGAAGDSD----------
MMAR_3758|M.marinum_M -----------------------------GAVSGRPGQNGSEGQPG----
Rv3507|M.tuberculosis_H37Rv GGFAGNGNAGGNGGTGGASEDGDNGNAGSGATGGTGGNGGTGGDGGAAGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
Mb3543|M.bovis_AF2122/97 GGLGG-----------------------AGAGGGADGDDGDDGQPGNNGS
MUL_4367|M.ulcerans_Agy99 GGDGGDGGDGGFGVIGGQGGGGGFGGLGGTGAGGAPSDKGINGEPGNPG-
MSMEG_0868|M.smegmatis_MC2_155 SEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------
Mvan_1264|M.vanbaalenii_PYR-1 ------
MMAR_3758|M.marinum_M ------
Rv3507|M.tuberculosis_H37Rv GGVA--
MLBr_01183|M.leprae_Br4923 ------
Mb3543|M.bovis_AF2122/97 ------
MUL_4367|M.ulcerans_Agy99 ------
MSMEG_0868|M.smegmatis_MC2_155 TGANNP
TH_3810|M.thermoresistible__bu ------
MAB_4284c|M.abscessus_ATCC_199 ------
MAV_4827|M.avium_104 ------