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VMVVDDHPIWRDAVARDLADDGFDVVATADGVASAKRRAAVVQPAVVLMDMRLADGDGAQATAEVLAVSP SSRVLVLSASDERDDVLEAVKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEFRRIERDS PAGPTLTERETEILRHVAKGLTAKQIASRLSLSHRTVENHVQATFRKLQIGNRVELARYAIEHGLDE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2836 | - | - | 100% (207) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2548 | - | 1e-26 | 35.68% (199) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1427 | - | 1e-24 | 32.32% (198) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0867c | narL | 2e-30 | 37.86% (206) | nitrate/nitrite response transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3579 | - | 1e-105 | 93.81% (210) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0844c | narL | 1e-30 | 37.86% (206) | nitrate/nitrite response transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02123 | - | 8e-11 | 30.90% (178) | two-component response regulator |
| M. abscessus ATCC 19977 | MAB_4519c | - | 2e-82 | 75.83% (211) | two-component LuxR family response regulator |
| M. marinum M | MMAR_3959 | - | 6e-92 | 81.90% (210) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_4114 | - | 3e-90 | 81.43% (210) | response regulator receiver domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3240 | - | 1e-98 | 88.15% (211) | DNA-binding response regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3563 | - | 3e-93 | 84.76% (210) | PUTATIVE DNA-binding response regulator, LuxR family protein |
| M. ulcerans Agy99 | MUL_3814 | - | 5e-91 | 80.95% (210) | two component transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0867c|M.bovis_AF2122/97 MS-NPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALEL
Rv0844c|M.tuberculosis_H37Rv MS-NPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALEL
Mvan_2836|M.vanbaalenii_PYR-1 -----------MMVVDDHPIWRDAVARDLADDG-FDVVATADGVASAKRR
Mflv_3579|M.gilvum_PYR-GCK -M--GIDRT-SVMVVDDHPIWRDAVARDLADDG-FDVVATADGVASAKRR
MSMEG_3240|M.smegmatis_MC2_155 MM--TDAAP-TVMVVDDHPIWRDAVARDLADDG-FDVVATADGVASASRR
TH_3563|M.thermoresistible__bu MG--EPQQP-TVMVVDDHPIWREAVARDLAEAG-LSVVATADGVAAARRR
MMAR_3959|M.marinum_M MS--EHESP-TVMVVDDHPIWRDAVARDLSDDG-FAVVATADGVATAQRR
MUL_3814|M.ulcerans_Agy99 MS--EHESP-TVMVVDDHPIWRDAVARDLSDDG-FAVVATADGVATAQRR
MAV_4114|M.avium_104 MT--DDATPTTVMVVDDHPIWRDAVARDLAESG-FAVVATADGVATAQRR
MAB_4519c|M.abscessus_ATCC_199 MTGNTDSEQISVMVVDDHPMWRDGVSRDLQAAG-LRVVATADGVASSGRI
MLBr_02123|M.leprae_Br4923 MD--TGVSSPRVLVVDDDSDVLASLERGLRLSG--FEVSTAIDGAEALRN
::* **.. .: * * * *. * . * : .
Mb0867c|M.bovis_AF2122/97 IKAHLPDVALLDYRMPGMDGAQVPAAVRSYELPTRVLLISAHDEPAIVYQ
Rv0844c|M.tuberculosis_H37Rv IKAHLPDVALLDYRMPGMDGAQVAAAVRSYELPTRVLLISAHDEPAIVYQ
Mvan_2836|M.vanbaalenii_PYR-1 AAVVQPAVVLMDMRLADGDGAQATAEVLAVSPSSRVLVLSASDERDDVLE
Mflv_3579|M.gilvum_PYR-GCK AAVVRPDVVVMDMRLGDGDGAQATTEVLAVSPSSRILVLSASDERDDVLE
MSMEG_3240|M.smegmatis_MC2_155 AAVVRPDVVLMDMRLGDGSGAQATAEVLAVSPRSRVLVLSASDERDDVLQ
TH_3563|M.thermoresistible__bu AAAVRPDVVLMDMRLPDGDGARATAEVRAVSPDSRVLVLSASEERDDVLE
MMAR_3959|M.marinum_M AAIVKPDVVVMDMRLADGDGVQATTEVLKVSPATRVLVLSASDEREDVLE
MUL_3814|M.ulcerans_Agy99 AAIVKPDVVVMDMRLADGDGVQATTEVLKVSPATRVLVLSTSDEREDVLE
MAV_4114|M.avium_104 AGVVRPDVVVMDMQLPDGDGAQATAAVLAVSPSSRVLVLSASDERDDVLQ
MAB_4519c|M.abscessus_ATCC_199 AATVKPDVVLMDMQLTDGDGAQATAAVLSASPHSHILVLSASAEREDVLE
MLBr_02123|M.leprae_Br4923 ATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVA
* . ::* .: .*. . : : . : ::*: .
Mb0867c|M.bovis_AF2122/97 ALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIRQRAA
Rv0844c|M.tuberculosis_H37Rv ALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIRQRAA
Mvan_2836|M.vanbaalenii_PYR-1 AVKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEFRRIER
Mflv_3579|M.gilvum_PYR-GCK AVKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEFRRIEQ
MSMEG_3240|M.smegmatis_MC2_155 AVKAGATGYLVKSASRTELADAVRATAEGRAVFTPGLAGLVLGEYRRIAQ
TH_3563|M.thermoresistible__bu AVKAGATGYLVKSASKTELVDAVHATAQGRAVFTPGLAGLVLGEYRRISR
MMAR_3959|M.marinum_M AVKAGATGYLVKSASKAELADAVRATAAGRAVFTPSLAGLVLGEYRRIAQ
MUL_3814|M.ulcerans_Agy99 AVKTGATGYLVKSASKAELADAVRATAAGRAVFTPSLAGLVLGEYRRIAQ
MAV_4114|M.avium_104 AVKAGAAGYLVKSASKAELAQAVTDTAAGRAVFTPSLAGLVLGEYRRIAQ
MAB_4519c|M.abscessus_ATCC_199 AVKAGATGYLVKSASAAELIDAVRATAKGQAVFTPGLAGLVLGEFRRMSS
MLBr_02123|M.leprae_Br4923 GLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSETIAVGPLEVDI
.:: ** .:*:* *: * : . :.. : .
Mb0867c|M.bovis_AF2122/97 P--------VAPVLSAREREVLNRIACGQSIPAIAAELYVAPS-------
Rv0844c|M.tuberculosis_H37Rv P--------VAPVLSAREREVLNRIACGQSIPAIAAELYVAPS-------
Mvan_2836|M.vanbaalenii_PYR-1 D---SPAG---PTLTERETEILRHVAKGLTAKQIASRLSLSHR-------
Mflv_3579|M.gilvum_PYR-GCK S---SPAGADGPTLTERETEILRYVAKGLTAKQIASRLSLSHR-------
MSMEG_3240|M.smegmatis_MC2_155 QP--AQEGPATPTLTERETEILRYVAKGLTAKQIAARLSLSHR-------
TH_3563|M.thermoresistible__bu Q---PGAGPDAPRLTERETEILRYVAKGLTAKQIAAQLSLSHR-------
MMAR_3959|M.marinum_M T---ADSSQDRPSLTERETEILRYVAKGLSAKQIAEKLSLSHR-------
MUL_3814|M.ulcerans_Agy99 T---ADSSQDRPSLTERETEILRYVAKGLSAKQIAEKLSLSHR-------
MAV_4114|M.avium_104 S---KDDGPTRPRLTDRETEVLRYVAKGLSAKQIAEKLSLSHR-------
MAB_4519c|M.abscessus_ATCC_199 AP--AADADETPRLSDRETEVLRLVAKGLSAKQIATRLSLSHR-------
MLBr_02123|M.leprae_Br4923 PGRRARVNGVDVDLTKREFDLLAVLAEHKTTVLSRAQLLELVWGYDFAAD
*: ** ::* :* : .*
Mb0867c|M.bovis_AF2122/97 --TVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD---
Rv0844c|M.tuberculosis_H37Rv --TVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD---
Mvan_2836|M.vanbaalenii_PYR-1 --TVENHVQATFRKLQIGNRVELARYAIEHGLDE---
Mflv_3579|M.gilvum_PYR-GCK --TVENHVQATFRKLQVGNRVELARYAIEHGLDE---
MSMEG_3240|M.smegmatis_MC2_155 --TVENHVQATFRKLQVANRVELARYAIEHGLDE---
TH_3563|M.thermoresistible__bu --TVENHVQATFRKLQVANRVELARYAIEHGLDE---
MMAR_3959|M.marinum_M --TVENHVQATFRKLQVANRVELTRYAIEHGLDK---
MUL_3814|M.ulcerans_Agy99 --TVENHVQATFRKLQLANRVELTRYAIEHGLDK---
MAV_4114|M.avium_104 --TVENHVQATFRKLQVANRVELARYAIEHGLDEEP-
MAB_4519c|M.abscessus_ATCC_199 --TVENHVQSTLRKLQLGNRVELTRYAIEHGLDE---
MLBr_02123|M.leprae_Br4923 TNVVDVFIGYLRRKLEANSGPRLLHTVRGVGFVLRMQ
.*. .: .** . . :