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MVVVGTDAHKYSHTFVATDEVGRQLGEKTVKATTAGHATAIMWAREQFGLELIWGIEDCRNMSARLERDL LAAGQQVVRVPTKLMAQTRKSARSRGKSDPIDALAVARAVMRETDLPLATHDETSRELKLLTDRRDVLVA QRTSAINRLRWLVHELDPERAPAARSLDAAKHQQALRTWLDTQPGLVAELARAELTDIIRLTGEINTLAQ RISARVHQVAPALLEIPGCAELTAAKIVGEAAGVTRFKSEAAFACHAAVAPIPVWSGNTAGQMRLSRSGN RQLNAALHRIALTQIRMTDSRGQAYYQRLQDAGKTKRAALRCLKRRLARTVFQALRTVHQPSSEHTQPAA ACHRSYCSRSCLSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0797 | - | - | 100% (364) | IS1547 transposase |
| M. tuberculosis H37Rv | Rv3327 | - | 0.0 | 99.72% (358) | transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0820 | - | 0.0 | 99.73% (364) | IS1547 transposase |
| M. gilvum PYR-GCK | Mflv_0450 | - | 1e-126 | 67.95% (337) | transposase IS116/IS110/IS902 family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1421 | - | 7e-05 | 31.41% (156) | hypothetical protein MAB_1421 |
| M. marinum M | MMAR_3792 | - | 3e-30 | 31.62% (351) | transposase |
| M. avium 104 | MAV_1059 | - | 1e-140 | 71.51% (351) | putative transposase |
| M. smegmatis MC2 155 | MSMEG_6023 | - | 6e-31 | 33.14% (341) | transposase |
| M. thermoresistible (build 8) | TH_3017 | - | 6e-22 | 29.14% (350) | PUTATIVE transposase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0416 | - | 1e-18 | 26.12% (402) | transposase IS116/IS110/IS902 family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0797|M.tuberculosis_H37Rv --------------------------------------------------
Mb0820|M.bovis_AF2122/97 --------------------------------------------------
MAV_1059|M.avium_104 --------------------------------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3792|M.marinum_M --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 --------------------------------------------------
TH_3017|M.thermoresistible__bu --------------------------------------------------
Mvan_0416|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1421|M.abscessus_ATCC_1997 MKLHRLSVTNYRGITHRDITFPERGVVVVGGANEVGKTSMIEALDLLIES
Rv0797|M.tuberculosis_H37Rv --------------------------------MVVVGTDAHKYSHTFVAT
Mb0820|M.bovis_AF2122/97 --------------------------------MVVVGTDAHKYSHTFVAT
MAV_1059|M.avium_104 --------------------------------MVVVGADVHKHTHTFVAV
Mflv_0450|M.gilvum_PYR-GCK --------------------------------MVIVGTDVHKRTHTFVAV
MMAR_3792|M.marinum_M -------------------------MIVAEAFGYVVGIDTHARTHTYCIL
MSMEG_6023|M.smegmatis_MC2_155 -------------------------MTPSQIV--VIGADTHLDTIHLAAL
TH_3017|M.thermoresistible__bu ------------------------------------------------VV
Mvan_0416|M.vanbaalenii_PYR-1 -----------------------------MTTGQVWAGVDVGKEHHWVCA
MAB_1421|M.abscessus_ATCC_1997 KDRSTKKDVKQVKPTFADVGSEVEAEISCGPYRFVYRKRFHKRAETHLTV
Rv0797|M.tuberculosis_H37Rv -DEVGRQLGEKTVKA----------------TTAGHATAIMWAREQFG-L
Mb0820|M.bovis_AF2122/97 -DEVGRQLGEKTVKA----------------TTAGHATAIMWAREQFG-L
MAV_1059|M.avium_104 -DEVGRKLGEKTVKA----------------LTSGHAEAVMWARERFG-A
Mflv_0450|M.gilvum_PYR-GCK -DEVGRKLGEKVVPA----------------TTAGHRTAVAWAREQFG-D
MMAR_3792|M.marinum_M NARTGAIVVGATFPN----------------TSPAHRRVIAWIQRHCPNT
MSMEG_6023|M.smegmatis_MC2_155 -SETGKPLGDAEFPT----------------RPSGYYVAVKWAQSFG--T
TH_3017|M.thermoresistible__bu IDAQGKRLLSQRVAN----------------DEATLLKLISTVATMADGG
Mvan_0416|M.vanbaalenii_PYR-1 VDDSGKVVLSRRLVN----------------DEQPIRELVAEIDELAER-
MAB_1421|M.abscessus_ATCC_1997 IEPRREQLSGDEAHQRVLDMLDQSIDMNLWKAQRVLQSAGAGVLDLSSSD
:
Rv0797|M.tuberculosis_H37Rv ELIWGIEDCRNMSARLER----DLLAAGQQVVRVPTKLMAQTRKSARS-R
Mb0820|M.bovis_AF2122/97 ELIWGIEDCRNMSARLER----DLLAAGQQVVRVPTKLMAQTRKSARS-R
MAV_1059|M.avium_104 QVVWAIEDCRHLSARLER----DLLTAGQQVVRVPPKLMAQARASART-R
Mflv_0450|M.gilvum_PYR-GCK ELLWGIEDCRNLSARLEI----DLLGMAQSAVRVAPKLMSQSRACART-R
MMAR_3792|M.marinum_M KVLAAVEGTSSYGAGVTA----ALVDAGIDVTEV-----RPTGRHRAR-A
MSMEG_6023|M.smegmatis_MC2_155 VTLAGVEGTNSYGAGLTR----ALQDGGIDVVEVN----RPDRAARRR-R
TH_3017|M.thermoresistible__bu EVTWAIDLNAGGAALLIT----LLIAADQRLLYIPGRTVHHASGSYRG-E
Mvan_0416|M.vanbaalenii_PYR-1 -VSWTVDLTTVYAALVLT----VLADAGKTVRYLAGRAVWQASATYRGGE
MAB_1421|M.abscessus_ATCC_1997 ALTRALDLAAGQSVALSGSEPDLVERIDAEYALYFTGTGRPTGEWARAGA
:: .. : :
Rv0797|M.tuberculosis_H37Rv GKSDPIDALAVARAVMRE--TDLPLATHDETSRELKLLTDRRDVLVA---
Mb0820|M.bovis_AF2122/97 GKSDPIDALAVARAVLRE--TDLPLATHDETSRELKLLTDRRDVLVA---
MAV_1059|M.avium_104 GKSDPIDALAVARGFLRE--PDLPVASHDKVSRELKLLVDRREVLVA---
Mflv_0450|M.gilvum_PYR-GCK GKSDPIDALAVAHAVLRH--PDLPVAAHDEVSRELKLLTDRREDLVA---
MMAR_3792|M.marinum_M GKSDVIDAEAAARSVLGCEQQRLPIPRESGEREDLRILLAARRILDQ---
MSMEG_6023|M.smegmatis_MC2_155 GKSDPLDAYAAARTALSG--HGLAAPKDE-RTLALSALLTARRGAVK---
TH_3017|M.thermoresistible__bu GKTDAKDAAVIADQARMR-RDLQPLRPGDDITVELRILTSRRTDLVA---
Mvan_0416|M.vanbaalenii_PYR-1 AKTDAKDARVIADQARMRGQDLPVLHPDDDLISELRMLTGHRADLVA---
MAB_1421|M.abscessus_ATCC_1997 RLTAAEDALASARAAMAE--VDQQVREHDELTQELASVIADRAEVNRRLA
: ** . * . * : *
Rv0797|M.tuberculosis_H37Rv --------------------------------------QRTSAINRLRWL
Mb0820|M.bovis_AF2122/97 --------------------------------------QRTSAINRLRWL
MAV_1059|M.avium_104 --------------------------------------QRTAMINRLRWR
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------QRTSTINRLRQR
MMAR_3792|M.marinum_M --------------------------------------QRTANRNALTAL
MSMEG_6023|M.smegmatis_MC2_155 --------------------------------------AHTAATNQIQSL
TH_3017|M.thermoresistible__bu --------------------------------------DRTRTINRLRAQ
Mvan_0416|M.vanbaalenii_PYR-1 --------------------------------------DRTRTINRLRQQ
MAB_1421|M.abscessus_ATCC_1997 PLEEASQAVTTLVQQHDNAVVVAEAAQAAAVAAQTKRDERAQLVADIRAR
:: :
Rv0797|M.tuberculosis_H37Rv VHELDPERAPAARSLDAAKHQQALRTWLD---------------------
Mb0820|M.bovis_AF2122/97 VHELDPERAPAARSLDAAKHQQALRTWLD---------------------
MAV_1059|M.avium_104 VHELDPERAPGPASLDRGKHRHLLGAWLA---------------------
Mflv_0450|M.gilvum_PYR-GCK VHELDPAAEPNPGSLHRPTPCATLAAWLN---------------------
MMAR_3792|M.marinum_M LRTI--DLGIDARKPLTNDQVRVIAAWRG---------------------
MSMEG_6023|M.smegmatis_MC2_155 LVTAPSELRECYRRYTTRGLVKELARCRP---------------------
TH_3017|M.thermoresistible__bu LLEYFPALERAFDYSTSKAALLLLTGYQTPDGLRRAGAARLAVWLGKRKA
Mvan_0416|M.vanbaalenii_PYR-1 LVAVCPALERAAQPSQDRGWVILLARYQRPKAIRQSGVSRLTKVLTDAGV
MAB_1421|M.abscessus_ATCC_1997 RVSIDMLAEQLSATAEAHGTAQQVCEAAEAAAAQATESVDAARVQLEAAR
:
Rv0797|M.tuberculosis_H37Rv --------------------------------------------------
Mb0820|M.bovis_AF2122/97 --------------------------------------------------
MAV_1059|M.avium_104 --------------------------------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3792|M.marinum_M --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 --------------------------------------------------
TH_3017|M.thermoresistible__bu RNADAVAAKALQA-------------------------------------
Mvan_0416|M.vanbaalenii_PYR-1 RNAASIAAAAVAA-------------------------------------
MAB_1421|M.abscessus_ATCC_1997 GTLDRALARDEVDGLAARVSRIDLTNRQLASVGAELSSLVITAQSLGAIE
Rv0797|M.tuberculosis_H37Rv -TQPG-------LVAELARAELTDIIRLTGEINTLAQRISARVH--QVAP
Mb0820|M.bovis_AF2122/97 -TQPG-------LVAELARAELTDIIRLTGEINTLAQRISARVH--QVAP
MAV_1059|M.avium_104 -TVPG-------LVAELARDELADITRLTEAINALAKRIGSRVR--TVAP
Mflv_0450|M.gilvum_PYR-GCK -TQTG-------ILSELARDELADIVRLSEAINAVAARIGERVR--EVAP
MMAR_3792|M.marinum_M -NQKPSSTTAHAVARREARRLAKAVLEQTVQLDDNHRQLRGLAG--QAAP
MSMEG_6023|M.smegmatis_MC2_155 -TAHTDPTAVAVLTALKALAYRAQFLHH--QEHELTEQIHTLTQ--QMNP
TH_3017|M.thermoresistible__bu AHAQHTVIPGQQLAAAMVARLAKEVMALDTEIGDTDAMIEERFHRHRHAE
Mvan_0416|M.vanbaalenii_PYR-1 VKTQTMRLPGEEVAAGLIADLAREVIALDDRIKTTDADIEGRFRRHPLAE
MAB_1421|M.abscessus_ATCC_1997 TAARAVGMAEAALETASAQVELRALVDVDIAVNGEQLRVAAGDRWSSAAT
: . :
Rv0797|M.tuberculosis_H37Rv ALLEIPG---------------------------CAE-LTAAKIVGEAAG
Mb0820|M.bovis_AF2122/97 ALLEIPG---------------------------CAE-LTAAKIVGEAAG
MAV_1059|M.avium_104 ALLAMPG---------------------------CAE-LTAAKLVGETAG
Mflv_0450|M.gilvum_PYR-GCK TLLALPG---------------------------CGE-LTAAKILGETAT
MMAR_3792|M.marinum_M GLQELPG---------------------------IGP-VTAAIIICAYSH
MSMEG_6023|M.smegmatis_MC2_155 GLRAAHG---------------------------VGPDTAAALLITAGMN
TH_3017|M.thermoresistible__bu IIVSMSG---------------------------FGVTLGAEFLAATGGD
Mvan_0416|M.vanbaalenii_PYR-1 VITSMPG---------------------------IGFRLGAEFLAAVG-D
MAB_1421|M.abscessus_ATCC_1997 DTIEITAPGVAVARIIPGPNAAQLRDKLDTARQTLSGALADAGVADVGEA
. . :
Rv0797|M.tuberculosis_H37Rv VTRFKSEAAFACHAAVAPIPVWSGNTAGQMRLSRSGNRQLNAALHRIALT
Mb0820|M.bovis_AF2122/97 VTRFKSEAAFACHAAVAPIPVWSGNTAGQMRLSRSGNRQLNAALHRIALT
MAV_1059|M.avium_104 VTRFKSEAAFARHAGVAPVPVWSGNTAGRVRMTRSGNRQLNAALHRIAIT
Mflv_0450|M.gilvum_PYR-GCK VSRFRSEAAFARHTGTAPIPVWSGNTAGRVRLSRSGNRQLNAALHRIAIT
MMAR_3792|M.marinum_M RGRIRSEAAFAALGGVAPLPASSGNTS-RHRLSRAGDRQLNRAFEVIVRT
MSMEG_6023|M.smegmatis_MC2_155 PHRLRSEAAFAALCGAAPVPASSGKTT-RHRLSRGGDRTANNALYRIALV
TH_3017|M.thermoresistible__bu MSAFDSVDRLAGVAGLAPVPRDSGRISGNLQRPRRYNRRLLRVCYLSALS
Mvan_0416|M.vanbaalenii_PYR-1 PALIGSADQLAAWAGLAPVSRDSGKRTGRLHTPKRYSRRLRRVMYMSALT
MAB_1421|M.abscessus_ATCC_1997 QKQFERRTELNAERDRLTALLDGLMGPESLEALREKLSRLRELVPEATGL
: : . . . . : .
Rv0797|M.tuberculosis_H37Rv QIRMTDSRGQAYYQRLQ-------DAGKTKRAALRCLKRRLARTVFQALR
Mb0820|M.bovis_AF2122/97 QIRMTDSRGQAYYQRLQ-------DAGKTKRAALRCLKRRLARTVFQALR
MAV_1059|M.avium_104 QIRLEG-LGQTYYRHRL-------AAGDSNPEALRCLKRRLARIIFGHLH
Mflv_0450|M.gilvum_PYR-GCK QIRLTDSAGQRYYRKRL-------AEGKATKEALRCLKRQLARIVYRHLH
MMAR_3792|M.marinum_M RMTCDP-ATRHYVARRT-------AEGMSKRETRRCLKRYVCRSVFRHLQ
MSMEG_6023|M.smegmatis_MC2_155 RMSNDP-RTPDYVARQT-------ANGRSKIEIIRLLKRAVAREVFRLLS
TH_3017|M.thermoresistible__bu SIRSDP-ASRTYYNRKR-------AEGKRHSQAVLALARRRLNVLWAMLR
Mvan_0416|M.vanbaalenii_PYR-1 AIRCDP-DSKAYYQRKR-------DEGKRPIPATICLARRRTNVLYALIR
MAB_1421|M.abscessus_ATCC_1997 WDAIDPAQARAEVARLVGEVERLQAEEVTHRRAVQTAGQQLAEKAAEAMA
: : . :
Rv0797|M.tuberculosis_H37Rv TVHQPSSEHTQPAAACHRSYCSRSCLSG----------------------
Mb0820|M.bovis_AF2122/97 TVHQPSSEHTQPAAACHRSYCSRSCLSG----------------------
MAV_1059|M.avium_104 TDHQHRTQPCQTAAA-----------------------------------
Mflv_0450|M.gilvum_PYR-GCK TDENTRKTKPHNNAQTAA--------------------------------
MMAR_3792|M.marinum_M AATT----------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 QPCAIDDYSDLRPARQAKNITLTTVANHLDVWPNDISRLERGLKRDDTLA
TH_3017|M.thermoresistible__bu DHTTYQPTTPTAAAAA----------------------------------
Mvan_0416|M.vanbaalenii_PYR-1 DNRTWQPDSPPVTAAA----------------------------------
MAB_1421|M.abscessus_ATCC_1997 AREKHAARAEELAAAEQRLAHVRSSASDDLLTERHERAVQAADLTSRRVT
Rv0797|M.tuberculosis_H37Rv --------------------------------------------------
Mb0820|M.bovis_AF2122/97 --------------------------------------------------
MAV_1059|M.avium_104 --------------------------------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3792|M.marinum_M --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 ANYREYLSAA----------------------------------------
TH_3017|M.thermoresistible__bu --------------------------------------------------
Mvan_0416|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1421|M.abscessus_ATCC_1997 DLVSQLAALEADRVRAELAEVSARAQALDRRHEATRDRLRDISVRLEVFG
Rv0797|M.tuberculosis_H37Rv --------------------------------------------------
Mb0820|M.bovis_AF2122/97 --------------------------------------------------
MAV_1059|M.avium_104 --------------------------------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3792|M.marinum_M --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 --------------------------------------------------
TH_3017|M.thermoresistible__bu --------------------------------------------------
Mvan_0416|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1421|M.abscessus_ATCC_1997 RQGRQDQLDAAASEREYAATEFARIGAKARAVDTLRSVMMRHRDGMRLRY
Rv0797|M.tuberculosis_H37Rv --------------------------------------------------
Mb0820|M.bovis_AF2122/97 --------------------------------------------------
MAV_1059|M.avium_104 --------------------------------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3792|M.marinum_M --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 --------------------------------------------------
TH_3017|M.thermoresistible__bu --------------------------------------------------
Mvan_0416|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1421|M.abscessus_ATCC_1997 VDPFRAELERLGRMVFGPTFEVDIDSDLSIRSRTLEGRTVPYESLSGGAK
Rv0797|M.tuberculosis_H37Rv --------------------------------------------------
Mb0820|M.bovis_AF2122/97 --------------------------------------------------
MAV_1059|M.avium_104 --------------------------------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3792|M.marinum_M --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 --------------------------------------------------
TH_3017|M.thermoresistible__bu --------------------------------------------------
Mvan_0416|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1421|M.abscessus_ATCC_1997 EQLGIVARLASAALVAPQDAVPVIIDDALGFTDSDRLERMGEVFGAVGTE
Rv0797|M.tuberculosis_H37Rv --------------------------
Mb0820|M.bovis_AF2122/97 --------------------------
MAV_1059|M.avium_104 --------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------
MMAR_3792|M.marinum_M --------------------------
MSMEG_6023|M.smegmatis_MC2_155 --------------------------
TH_3017|M.thermoresistible__bu --------------------------
Mvan_0416|M.vanbaalenii_PYR-1 --------------------------
MAB_1421|M.abscessus_ATCC_1997 TQVIVLTCSPDRYRAVTGAQRISLSA