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MVVVGTDAHKYSHTFVATDEVGRQLGEKTVKATTAGHATAIMWAREQFGLELIWGIEDCRNMSARLERDL LAAGQQVVRVPTKLMAQTRKSARSRGKSDPIDALAVARAVLRETDLPLATHDETSRELKLLTDRRDVLVA QRTSAINRLRWLVHELDPERAPAARSLDAAKHQQALRTWLDTQPGLVAELARAELTDIIRLTGEINTLAQ RISARVHQVAPALLEIPGCAELTAAKIVGEAAGVTRFKSEAAFACHAAVAPIPVWSGNTAGQMRLSRSGN RQLNAALHRIALTQIRMTDSRGQAYYQRLQDAGKTKRAALRCLKRRLARTVFQALRTVHQPSSEHTQPAA ACHRSYCSSHLGEPPRLTDMTQKTRIQPLPPKRAGLLIRALYRIAKRRFGEVPEPFTVTAHHRRLLIANV VHEALLQRASRKLPPSVRELAVFWTARSIGCSWCVDFGAMLQRLDGLDVDRLTDIDNYATSSKFSDDERA AIAYAEAMTADPHSVTDEQVADLRARFGEAGVIELTYQIGVENMRARMNSALGITEQGFNSGDACRVPWA APDVPSAESR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3327 | - | - | 100% (570) | PROBABLE TRANSPOSASE FUSION PROTEIN |
| M. tuberculosis H37Rv | Rv0797 | - | 0.0 | 99.72% (358) | IS1547 transposase |
| M. tuberculosis H37Rv | Rv2159c | - | 2e-07 | 34.94% (83) | hypothetical protein Rv2159c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3360 | - | 0.0 | 100.00% (570) | transposase |
| M. gilvum PYR-GCK | Mflv_0450 | - | 1e-126 | 68.25% (337) | transposase IS116/IS110/IS902 family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3677 | - | 6e-81 | 71.94% (196) | transposase fusion protein |
| M. marinum M | MMAR_1197 | - | 4e-92 | 83.25% (191) | hypothetical protein MMAR_1197 |
| M. avium 104 | MAV_1059 | - | 1e-140 | 71.79% (351) | putative transposase |
| M. smegmatis MC2 155 | MSMEG_6023 | - | 6e-31 | 33.43% (341) | transposase |
| M. thermoresistible (build 8) | TH_2184 | - | 8e-82 | 74.21% (190) | PROBABLE TRANSPOSASE FUSION PROTEIN |
| M. ulcerans Agy99 | MUL_3629 | - | 2e-22 | 36.93% (176) | hypothetical protein MUL_3629 |
| M. vanbaalenii PYR-1 | Mvan_1576 | - | 3e-81 | 75.00% (188) | hypothetical protein Mvan_1576 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0450|M.gilvum_PYR-GCK -----MVIVGTDVHKRTHTFVAVDEVGRKLGEKVVPATTAGHRTAVAWAR
MAV_1059|M.avium_104 -----MVVVGADVHKHTHTFVAVDEVGRKLGEKTVKALTSGHAEAVMWAR
Rv3327|M.tuberculosis_H37Rv -----MVVVGTDAHKYSHTFVATDEVGRQLGEKTVKATTAGHATAIMWAR
Mb3360|M.bovis_AF2122/97 -----MVVVGTDAHKYSHTFVATDEVGRQLGEKTVKATTAGHATAIMWAR
TH_2184|M.thermoresistible__bu --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1197|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 MTPSQIVVIGADTHLDTIHLAALSETGKPLGDAEFPTRPSGYYVAVKWAQ
Mflv_0450|M.gilvum_PYR-GCK EQFGDELLWGIEDCRNLSARLEIDLLGMAQSAVRVAPKLMSQSRACARTR
MAV_1059|M.avium_104 ERFGAQVVWAIEDCRHLSARLERDLLTAGQQVVRVPPKLMAQARASARTR
Rv3327|M.tuberculosis_H37Rv EQFGLELIWGIEDCRNMSARLERDLLAAGQQVVRVPTKLMAQTRKSARSR
Mb3360|M.bovis_AF2122/97 EQFGLELIWGIEDCRNMSARLERDLLAAGQQVVRVPTKLMAQTRKSARSR
TH_2184|M.thermoresistible__bu --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1197|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 S-FGTVTLAGVEGTNSYGAGLTRALQDGGIDVVEVN----RPDRAARRRR
Mflv_0450|M.gilvum_PYR-GCK GKSDPIDALAVAHAVLRHPDLPVAAHDEVS--------------------
MAV_1059|M.avium_104 GKSDPIDALAVARGFLREPDLPVASHDKVS--------------------
Rv3327|M.tuberculosis_H37Rv GKSDPIDALAVARAVLRETDLPLATHDETSRELKLLTDRRDVLVAQRTSA
Mb3360|M.bovis_AF2122/97 GKSDPIDALAVARAVLRETDLPLATHDETSRELKLLTDRRDVLVAQRTSA
TH_2184|M.thermoresistible__bu --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1197|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 GKSDPLDAYAAARTALSGHGLAAPKD------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1059|M.avium_104 --------------------------------------------------
Rv3327|M.tuberculosis_H37Rv INRLRWLVHELDPERAPAARSLDAAKHQQALRTWLDTQPGLVAELARAEL
Mb3360|M.bovis_AF2122/97 INRLRWLVHELDPERAPAARSLDAAKHQQALRTWLDTQPGLVAELARAEL
TH_2184|M.thermoresistible__bu --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1197|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1059|M.avium_104 --------------------------------------------------
Rv3327|M.tuberculosis_H37Rv TDIIRLTGEINTLAQRISARVHQVAPALLEIPGCAELTAAKIVGEAAGVT
Mb3360|M.bovis_AF2122/97 TDIIRLTGEINTLAQRISARVHQVAPALLEIPGCAELTAAKIVGEAAGVT
TH_2184|M.thermoresistible__bu --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1197|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1059|M.avium_104 --------------------------------------------------
Rv3327|M.tuberculosis_H37Rv RFKSEAAFACHAAVAPIPVWSGNTAGQMRLSRSGNRQLNAALHRIALTQI
Mb3360|M.bovis_AF2122/97 RFKSEAAFACHAAVAPIPVWSGNTAGQMRLSRSGNRQLNAALHRIALTQI
TH_2184|M.thermoresistible__bu --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1197|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0450|M.gilvum_PYR-GCK --------------------------------------------------
MAV_1059|M.avium_104 --------------------------------------------------
Rv3327|M.tuberculosis_H37Rv RMTDSRGQAYYQRLQDAGKTKRAALRCLKRRLARTVFQALRTVHQPSSEH
Mb3360|M.bovis_AF2122/97 RMTDSRGQAYYQRLQDAGKTKRAALRCLKRRLARTVFQALRTVHQPSSEH
TH_2184|M.thermoresistible__bu --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1197|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0450|M.gilvum_PYR-GCK ---------------------RELKLLTDRREDLVAQRTSTINR-LRQRV
MAV_1059|M.avium_104 ---------------------RELKLLVDRREVLVAQRTAMINR-LRWRV
Rv3327|M.tuberculosis_H37Rv TQPAAACHRSYCSSHLGEPPRLTDMTQKTRIQPLPPKRAGLLIR-ALYRI
Mb3360|M.bovis_AF2122/97 TQPAAACHRSYCSSHLGEPPRLTDMTQKTRIQPLPPKRAGLLIR-ALYRI
TH_2184|M.thermoresistible__bu ----------------------MSENQKTRIEPLSPERAPWWVR-LMYRY
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------MTTRLEPVPPHRASLLTR-LMWRY
MAB_3677|M.abscessus_ATCC_1997 ------------------------MTTTSRIAPIAPPNASLLTR-FMYRV
MMAR_1197|M.marinum_M ------------------------MTQKTRIEPLPPKRAGLLVG-ALYRI
MUL_3629|M.ulcerans_Agy99 ------------------------MGVSDHDAGIAAKIAFFFTKRKLARM
MSMEG_6023|M.smegmatis_MC2_155 -----------------ERTLALSALLTARRGAVKAHTAATNQIQSLLVT
: : . :
Mflv_0450|M.gilvum_PYR-GCK HELDPAAEPNPGS---LHRPTPCATLAAWLNTQTGILSELARDELADIVR
MAV_1059|M.avium_104 HELDPERAPGPAS---LDRGKHRHLLGAWLATVPGLVAELARDELADITR
Rv3327|M.tuberculosis_H37Rv AKRRFGEVPEPFT---VTAHHRRLLIANVVHEALLQRASRKLPPSVRELA
Mb3360|M.bovis_AF2122/97 AKRRFGEVPEPFT---VTAHHRRLLIANVVHEALLQRASRKLPPSVRELA
TH_2184|M.thermoresistible__bu ARRRFGEVPEPFT---VAAHHPGLLLSSAVHETLLEKTSSRLPANVRELA
Mvan_1576|M.vanbaalenii_PYR-1 AKRRFGEVPEPFA---VYAHHPGLMLTGAVHEGLLERTSSKVPASVRELA
MAB_3677|M.abscessus_ATCC_1997 TKRRYGQVPEPFT---VIAHHRKLMVAAAVHEQMLGSASQVLPTSVRELA
MMAR_1197|M.marinum_M AKRRLGEVPEPFS---VVAHHRRLLVANAVHETMVERASRTLPAGVRELA
MUL_3629|M.ulcerans_Agy99 AGLATADMLEPLR---IYAHIPRLLNAYGRLEQAESKLD-VLTARHRALA
MSMEG_6023|M.smegmatis_MC2_155 APSELRECYRRYTTRGLVKELARCRPTAHTDPTAVAVLTALKALAYRAQF
:
Mflv_0450|M.gilvum_PYR-GCK LSEAINAVAARIGERVREVAPTLLALP-GCGELTAAKILGETATVSRFRS
MAV_1059|M.avium_104 LTEAINALAKRIGSRVRTVAPALLAMP-GCAELTAAKLVGETAGVTRFKS
Rv3327|M.tuberculosis_H37Rv VFWTARSIGCSWCVDFGAMLQRLDGLD-VDRLTDIDNYATSSKFSDDERA
Mb3360|M.bovis_AF2122/97 VFWTARSIGCSWCVDFGAMLQRLDGLD-VDRLTDIDNYATSSKFSDDERA
TH_2184|M.thermoresistible__bu VYWTARKIGCSWCVDFGAMLARLDGLN-IEKLSRIDDYATSDLFDDDERA
Mvan_1576|M.vanbaalenii_PYR-1 VYWTARQIGCSWCVDFGSMLMRLDGLD-IARLKEIDDFATSPRFTDDERA
MAB_3677|M.abscessus_ATCC_1997 VFWTARTVGCSWCVDFGSMLQRLDGLD-VDRLKAIDDYATSPLYTEDERV
MMAR_1197|M.marinum_M VFWTARQIGCSWCVDFGSMLQRLDGLD-VHRLEDIDEYATSPLFSDDERA
MUL_3629|M.ulcerans_Agy99 ELKAATTVGCQYCIDLGSQIARELGIS-DQELLALANYRDASCFSEVDRL
MSMEG_6023|M.smegmatis_MC2_155 LHHQEHELTEQIHTLTQQMNPGLRAAHGVGPDTAAALLITAGMNPHRLRS
: . :
Mflv_0450|M.gilvum_PYR-GCK EAAFARHTGTAPIPVWSGNTAGRVRLSRSGNRQLNAALHRIAITQIR---
MAV_1059|M.avium_104 EAAFARHAGVAPVPVWSGNTAGRVRMTRSGNRQLNAALHRIAITQIR---
Rv3327|M.tuberculosis_H37Rv AIAYAEAMTADPHSVTDEQVADLR--ARFGEAGVIELTYQIGVENMR---
Mb3360|M.bovis_AF2122/97 AIAYAEAMTADPHSVTDEQVADLR--ARFGEAGVIELTYQIGVENMR---
TH_2184|M.thermoresistible__bu AIAYADAMTTDPHTVTDEQVADLR--RRFGDAGVIELTTQIGVENMR---
Mvan_1576|M.vanbaalenii_PYR-1 AIAYAAAMTTDPHTVTDEQVADLR--RRFGADGVIELTYQIGVENMR---
MAB_3677|M.abscessus_ATCC_1997 AIAYADAMTGNPHDITDEQVEDLR--RRFGDAGVIELTYQIGVENMR---
MMAR_1197|M.marinum_M AIAYAEAITTDPHTVTDKQVAELR--SRFGDAGVVELTYQIGLENMR---
MUL_3629|M.ulcerans_Agy99 ILDYAAAISRTPVAVSDELFAALR--AHFDAAALVGLTHIITLGNLR---
MSMEG_6023|M.smegmatis_MC2_155 EAAFAALCGAAPVPASSGKTTRHR-LSRGGDRTANNALYRIALVRMSNDP
:* * . : . * : .:
Mflv_0450|M.gilvum_PYR-GCK LTDSAGQRYYRKRLAEGKATKEALRCLKRQLARIVYRHLHTDENTRKTKP
MAV_1059|M.avium_104 LEG-LGQTYYRHRLAAGDSNPEALRCLKRRLARIIFGHLHTDHQHR-TQP
Rv3327|M.tuberculosis_H37Rv ARMNSALGITEQGFNSGDACRVPWAAPDVPSAESR---------------
Mb3360|M.bovis_AF2122/97 ARMNSALGITEQGFNSGDACRVPWAAPDVPSAESR---------------
TH_2184|M.thermoresistible__bu ARINTALGITEQGFSSGDACRIPWAARSDQPAGGPAGSR-----------
Mvan_1576|M.vanbaalenii_PYR-1 ARMNAALGITEQGFSSGDACRVPWASAAQAGQGATAAEKR----------
MAB_3677|M.abscessus_ATCC_1997 ARTYAALGITEQGFNSGDACRVPWAASPD-PMGT----------------
MMAR_1197|M.marinum_M ARMNAALGITEQGFNSGDACRVPWATVEP-QFGR----------------
MUL_3629|M.ulcerans_Agy99 ARFNIALGIGSSGFSSDRVCALPEGAGPP---------------------
MSMEG_6023|M.smegmatis_MC2_155 RTPDYVARQTANGRSKIEIIRLLKRAVAREVFRLLSQPCAIDDYSDLRPA
Mflv_0450|M.gilvum_PYR-GCK HNNAQTAA--------------------------------------
MAV_1059|M.avium_104 CQTAAA----------------------------------------
Rv3327|M.tuberculosis_H37Rv ----------------------------------------------
Mb3360|M.bovis_AF2122/97 ----------------------------------------------
TH_2184|M.thermoresistible__bu ----------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 ----------------------------------------------
MAB_3677|M.abscessus_ATCC_1997 ----------------------------------------------
MMAR_1197|M.marinum_M ----------------------------------------------
MUL_3629|M.ulcerans_Agy99 ----------------------------------------------
MSMEG_6023|M.smegmatis_MC2_155 RQAKNITLTTVANHLDVWPNDISRLERGLKRDDTLAANYREYLSAA