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VSFVIAQPEMIAAAAGELASIRSAINAANAAAAAQTTGVMSAAADEVSTAVAALFSSHAQAYQAASAQAA AFHAQVVRTLTVDAGAYASAEAANAGPNMLAAVNAPAQALLGRPLIGNGANGAPGTGQAGGDGGLLFGNG GNGGSGAPGQAGGAGGAAGFFGNGGNGGDGGAGANGGAGGTAGWFFGFGGNGGAGGIGVAGINGGLGGAG GDGGNAGFFGNGGNGGMGGAGAAGVNAVNPGLATPVTPAANGGNGLNLVGVPGTAGGGADGANGSAIGQA GGAGGDGGNASTSGGIGIAQTGGAGGAGGAGGDGAPGGNGGNGGSVEHTGATGSSASGGNGATGGNGGVG APGGAGGNGGHVSGGSVNTAGAGGKGGNGGTGGAGGPGGHGGSVLSGPVGDSGNGGAGGDGGAGVSATDI AGTGGRGGNGGHGGLWIGNGGDGGAGGVGGVGGAGAAGAIGGHGGDGGSVNTPIGGSEAGDGGKGGLGGD GGGRGIFGQFGAGGAGGAGGVGGAGGAGGTGGGGGNGGAIFNAGTPGAAGTGGDGGVGGTGAAGGKGGAG GSGGVNGATGADGAKGLDGATGGKGNNGNPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0297 | PE_PGRS5 | - | 100% (591) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv0872c | PE_PGRS15 | e-167 | 52.35% (617) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv2487c | PE_PGRS42 | e-166 | 49.29% (702) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0305 | PE_PGRS5 | 0.0 | 97.52% (606) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-114 | 46.74% (537) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 1e-14 | 41.30% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-49 | 36.19% (467) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_5135 | - | 1e-164 | 50.22% (669) | PE-PGRS family protein, PE_PGRS15 |
| M. avium 104 | MAV_4827 | - | 5e-25 | 42.78% (180) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 8e-95 | 40.29% (623) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-43 | 40.14% (289) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3318 | - | 1e-148 | 47.99% (648) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-114 | 45.99% (548) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0297|M.tuberculosis_H37Rv --------------------------------------------------
Mb0305|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M --------------------------------------------------
MUL_3318|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0297|M.tuberculosis_H37Rv --------------------------------------------------
Mb0305|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M --------------------------------------------------
MUL_3318|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0297|M.tuberculosis_H37Rv --------------------------------------------------
Mb0305|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M --------------------------------------------------
MUL_3318|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0297|M.tuberculosis_H37Rv --------------------------------------------------
Mb0305|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M --------------------------------------------------
MUL_3318|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0297|M.tuberculosis_H37Rv --------------------------------------------------
Mb0305|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M --------------------------------------------------
MUL_3318|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv0297|M.tuberculosis_H37Rv -------------------------MS-FVIAQPEMIAAAAGE-------
Mb0305|M.bovis_AF2122/97 -------------------------MS-FVIAQPEMIAAAAGE-------
MLBr_01183|M.leprae_Br4923 -------------------------MPLFLNAEPQALTAAANT-------
MMAR_5135|M.marinum_M -------------------------MS-YVVAASDLLASTATE-------
MUL_3318|M.ulcerans_Agy99 -------------------------MS-YLAIAPEIVAAAAAD-------
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRG-------
MAB_4284c|M.abscessus_ATCC_199 ---------MSIIDFILNLFRDPVEAASYVADPEAALANAGLS-------
MAV_4827|M.avium_104 -----------------MNIVLGVSMAPSSIQMVVLEGEYADG-------
.
Rv0297|M.tuberculosis_H37Rv -------------LASIRSAINAANAAAAAQTTGVM-----SAAADEVST
Mb0305|M.bovis_AF2122/97 -------------LASIRSAINAANAAAAAQTTGVM-----SAAADEVST
MLBr_01183|M.leprae_Br4923 -------------LEGLSAATVASNAAAAQLTTEIA-----PPAADDVSI
MMAR_5135|M.marinum_M -------------LARIDAALNTANAAAVLPTTVLQ-----AAGADEVSA
MUL_3318|M.ulcerans_Agy99 -------------MDGIGSPITAANAAAAIPTSAIA-----AAAADEISA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu ---------------GDGGDGGLGGNGGHGGGTGIIS--LLSLAGNGGNG
MAB_4284c|M.abscessus_ATCC_199 -------------AVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHD
MAV_4827|M.avium_104 -------------ATVEEDAIDVTGADDAATASAPDRVISAILGTREGAA
Rv0297|M.tuberculosis_H37Rv AVAALFSSHAQAYQAASAQAAAFHAQVVRTLTVDAG-------------A
Mb0305|M.bovis_AF2122/97 AVAALFSSHAQAYQAASAQAAAFHAQVVRTLTVDAG-------------A
MLBr_01183|M.leprae_Br4923 LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSS-------------A
MMAR_5135|M.marinum_M AVAALFSSHARAYQALSVQAGQFHQWFTQTLSGAGL-------------S
MUL_3318|M.ulcerans_Agy99 AIAELFGNHAQQYQALSAQMARFHDQFVRSLSGAAQ-------------T
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu GNGYRTTDNNALDGGHGGNGGNVGFFSLFNLGGAGG--------------
MAB_4284c|M.abscessus_ATCC_199 LSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDT------------D
MAV_4827|M.avium_104 DAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVS---------AFL
.
Rv0297|M.tuberculosis_H37Rv YASAEAANAGPN------MLAAVNAPAQALLGRP----LIGN--------
Mb0305|M.bovis_AF2122/97 YASAEAANAGPN------MLAAVNAPAQALLGRP----LIGN--------
MLBr_01183|M.leprae_Br4923 YAGTETANHDS--------L------------------------------
MMAR_5135|M.marinum_M YASAEAANVSPLQVLERDVLGLVNAPTQALLGRP----IIGN--------
MUL_3318|M.ulcerans_Agy99 YARAEATGAAPLQP----VLDLINGPTQALLGRP----LIGNGTSGALGT
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGG----T
TH_3810|M.thermoresistible__bu WGGSGVDGVDVVG-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 FASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFG----------------
MAV_4827|M.avium_104 AAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETS--------------
.
Rv0297|M.tuberculosis_H37Rv -------------GANGAPGTGQAGGDGGLL----FGNGGNGGSGAPGQA
Mb0305|M.bovis_AF2122/97 -------------GANGAPGTGQAGGDGGLL----FGNGGNGGSGAPGQA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M -------------GADGAPGSGANGADGGIL----IGNGGTGGSGAPGQN
MUL_3318|M.ulcerans_Agy99 GQAGGDGGLLIGNGTSGALGTGQAGGDGGLL----IGNGGAGGSGAAGQA
Mflv_5091|M.gilvum_PYR-GCK -----AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGA
Mvan_1264|M.vanbaalenii_PYR-1 -----VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQA
MSMEG_0868|M.smegmatis_MC2_155 VDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGD
TH_3810|M.thermoresistible__bu ------------------------------------GNPDGGTPGAHGES
MAB_4284c|M.abscessus_ATCC_199 ---------------DLQFGNRDTTAIG-------DGAVAVGGSNSGPIA
MAV_4827|M.avium_104 ------------DGSIPDVYKQQIRAES---------YGDAAGQLSAMVA
Rv0297|M.tuberculosis_H37Rv GGAG---GAAGFFGNG--------------------GNGGDGGAGANGGA
Mb0305|M.bovis_AF2122/97 GGAG---GAAGFFGNG--------------------GNGGDGGAGANGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M GGAG---GNAGLLGSG--------------------GTGGVGGAGATGGT
MUL_3318|M.ulcerans_Agy99 GGAGGAGGAAGLIGSG--------------------GAGGIGGTGAAGGK
Mflv_5091|M.gilvum_PYR-GCK GGLGETGTTGGAGGVG--------------------GQGTAGGTGGVGGI
Mvan_1264|M.vanbaalenii_PYR-1 GTAGETGVTGGVGGIG--------------------GQGTEGGTGGVGGV
MSMEG_0868|M.smegmatis_MC2_155 GGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGM
TH_3810|M.thermoresistible__bu HTPG----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SGQGSTAVNGDVRDSN------------------IINADHGSNVGVDQSQ
MAV_4827|M.avium_104 GLEKLESLPGGLLLVG---------------------SGVDVAPLKQVLQ
Rv0297|M.tuberculosis_H37Rv GGTA----------------------------------------------
Mb0305|M.bovis_AF2122/97 GGTA----------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M GGTG----------------------------------------------
MUL_3318|M.ulcerans_Agy99 GGN-----------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGAG----------STGAVGG-------VGGKG----IQGGQG-------
Mvan_1264|M.vanbaalenii_PYR-1 GGVG----------ATGGAGG-------VGGKG----IQGGQG-------
MSMEG_0868|M.smegmatis_MC2_155 GEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TRVG----------------------------------------------
MAV_4827|M.avium_104 TTT-----------------------------------------------
Rv0297|M.tuberculosis_H37Rv -----GWFFGFGGNGGAGGIG-------------------------VAGI
Mb0305|M.bovis_AF2122/97 -----GWFFGFGGNGGAGGIG-------------------------VAGI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M -----GLLWGNGGIGGQGGTA-------------------------MAGV
MUL_3318|M.ulcerans_Agy99 -----AVLFGAGGNGGIGGTG-------------------------AVGG
Mflv_5091|M.gilvum_PYR-GCK ------LQGGKGGDGGAGGKGGDADSMGS------------------AGA
Mvan_1264|M.vanbaalenii_PYR-1 ------LQGGQGGDGGTGGTGGDATSMGE------------------AGA
MSMEG_0868|M.smegmatis_MC2_155 SGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASA
TH_3810|M.thermoresistible__bu ------VYTDRQGEDGEDGTG---------------------------TG
MAB_4284c|M.abscessus_ATCC_199 -----GDYTNVSGHGSADIDKS-------------------------VTV
MAV_4827|M.avium_104 -----FLDVSVAEEPETALARG-------------------------AAL
Rv0297|M.tuberculosis_H37Rv NGGLGGAGGDGGNAGFFGN---------------GGNGGMGGAG------
Mb0305|M.bovis_AF2122/97 NGGLGGAGGDGGNAGFFGN---------------GGNGGMGGAG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M NGGSPGHGGNGGNAFLFGD---------------GGTGGQGGTG------
MUL_3318|M.ulcerans_Agy99 TGAVGGAGGNGG--FLFGH---------------GGDGGTGGTG------
Mflv_5091|M.gilvum_PYR-GCK TGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD-------
Mvan_1264|M.vanbaalenii_PYR-1 TGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN-------
MSMEG_0868|M.smegmatis_MC2_155 NGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYD
TH_3810|M.thermoresistible__bu IGGRGGNGGSSSGTHPMAE-------------------------------
MAB_4284c|M.abscessus_ATCC_199 VDDHSQRNTTNINDSFNTDR--------------STNIGSGNTTN-----
MAV_4827|M.avium_104 AAANAPLFASSTAALAYAQ-------------------------------
Rv0297|M.tuberculosis_H37Rv --------------AAGVNAVNPGLATPVTPAANGGNGLN----------
Mb0305|M.bovis_AF2122/97 --------------AAGVNAVNPGLATPVTPAANGGNGLN----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M --------------LAGADGVNP---TPTGTAGTGAAGGN----------
MUL_3318|M.ulcerans_Agy99 --------------ASAAAGANGGAGQTGLAGTDGGTGGASG--------
Mflv_5091|M.gilvum_PYR-GCK ---------------GGTGGAGGAGGTGG-TGGAGGTGG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------GGTGGNGGNGGTGG-TGGNGGTGG-----------
MSMEG_0868|M.smegmatis_MC2_155 PNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQH
TH_3810|M.thermoresistible__bu ----------------DGEHVKALDGRPGLDGGNGSHGGN----------
MAB_4284c|M.abscessus_ATCC_199 --------------TEIGSHNQANIGTSTSAGGSAAVGGN----------
MAV_4827|M.avium_104 --------------DPGTGAVDQYSLPDYLYVPVDPEPGD----------
Rv0297|M.tuberculosis_H37Rv -----LVGVPGTAGGGADGANGSAIGQAGGAGGDGGNASTSGGIG-IAQT
Mb0305|M.bovis_AF2122/97 -----LVGVPGTAGGGADGANGSAIGQAGGAGGDGGNASTSGGIG-IAQT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M -----VSGNGPLTGGNGDTGDTGGTGETGGTGGAGGSATASSGSA-TGGK
MUL_3318|M.ulcerans_Agy99 --EGGAGGKGGLLFGAGGEGGAGGTGGAGGTGGAGGDGLAATTAGGTGGN
Mflv_5091|M.gilvum_PYR-GCK ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 ------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 STGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGD
TH_3810|M.thermoresistible__bu -------------GGHGGRGGFLGIGGSGGWGGHGGNGGDTDADGGNGGD
MAB_4284c|M.abscessus_ATCC_199 ----------AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA
MAV_4827|M.avium_104 -----DELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAV
Rv0297|M.tuberculosis_H37Rv GGAGGAGGAGGDGAPG----GNGGNGGSVEHTGAT---------GSSASG
Mb0305|M.bovis_AF2122/97 GGAGGAGGAGGDGAPG----GNGGNGGSVEHTGAT---------GSSASG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M GGAGGDPGGGANGGAG----GAGGDAESFSGQAHG---------GAGGDG
MUL_3318|M.ulcerans_Agy99 AGDGGEGGAGGNAGAG----GAGGQGGLFGNAGTT---------GAGGDG
Mflv_5091|M.gilvum_PYR-GCK GGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNG
TH_3810|M.thermoresistible__bu GGNGGSAGRGGTGGLR----------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAG-----LAGNAGLAGNAGLAG--------NAGLAG
MAV_4827|M.avium_104 VGISAVLALEIALAIG---IRTTGTVALQPTPNQH---------LIVPTE
Rv0297|M.tuberculosis_H37Rv GNG-------------------------------------ATGGNGGVGA
Mb0305|M.bovis_AF2122/97 GNG-------------------------------------ATGGNGGVGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M SQGGIPGGSGGAGGDGGKATGLASGIGGDGGDGGRGFATDVSGGTAGGGG
MUL_3318|M.ulcerans_Agy99 GNG----------------------------------------GNGGLAG
Mflv_5091|M.gilvum_PYR-GCK GTGGAG-----------------DGTGGTGGTGG----TGGQGGQGGQGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAG-----------------DGLGGTGGTGG----TGGFGGQGGQGG
MSMEG_0868|M.smegmatis_MC2_155 GNGGAGRIRVNNG------TATGTATGGNGGNGGNGDADGHRGGKGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NAG--------------------------------------LAGNAGLAG
MAV_4827|M.avium_104 QAP-------------------------------------APPPVQASAP
Rv0297|M.tuberculosis_H37Rv -----------------PGGAGGNGGHVSGGSVN----------------
Mb0305|M.bovis_AF2122/97 -----------------PGGAGGNGGHVSGGSVN----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M -----------------TGGDGGRGGLLIGSGGNGG--------------
MUL_3318|M.ulcerans_Agy99 -----------------NGGAGGNGDASNPNGGTGG--------------
Mflv_5091|M.gilvum_PYR-GCK -----------------TGGTGGQGG-LGGGGGTG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------TGGTGGQGG-LGGVGGTG---------------
MSMEG_0868|M.smegmatis_MC2_155 EALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------NAGLAGNAGLAGNAGLAGN--------------
MAV_4827|M.avium_104 -----------------QPKISVPEPVAAPKPLSPP--------------
Rv0297|M.tuberculosis_H37Rv ------TAGAGGKGGNGGTGGAGGPGGHGGSVLSGPVGDSGNGGAGGDGG
Mb0305|M.bovis_AF2122/97 ------TAGAGGKGGNGGTGGAGGPGGHGGSVLSGPVGDSGNGGAGGDGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M ------TGGTGGTGGTGAAAGVGGIGGDGGDATAASSATGGHGGDGGDSD
MUL_3318|M.ulcerans_Agy99 ------NAANPGAGGAGGAGGNGSRTGAPGTTGNTPTTAAGHGGKGGDGF
Mflv_5091|M.gilvum_PYR-GCK --------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGG
Mvan_1264|M.vanbaalenii_PYR-1 --------GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGG
MSMEG_0868|M.smegmatis_MC2_155 QASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGI
TH_3810|M.thermoresistible__bu --------GVFGINGGNGRAGLGGRGXX------------XXGGGVGAAV
MAB_4284c|M.abscessus_ATCC_199 -------AGLAGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGVL
MAV_4827|M.avium_104 ------VAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPV
Rv0297|M.tuberculosis_H37Rv AGVSATDIAGTGGRGG-NGGHGGLWIGNGGDGGAGGVGGVGGAGAAGAIG
Mb0305|M.bovis_AF2122/97 AGVSATDIAGTGGRGG-NGGHGGLWIGNGGDGGAGGVGGVGGAGAAGAIG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M PSVGTGGNGGTGGNGG-NGGAASLLFGNGGSGGDGGVGGTGGTGGAGGSG
MUL_3318|M.ulcerans_Agy99 NPATSGQDGGSGGKGG-DAG----QFGNGGNGGNGAAGDAAGSGHTGGNG
Mflv_5091|M.gilvum_PYR-GCK LGG-LGGFGGSGGTGG-QGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG
Mvan_1264|M.vanbaalenii_PYR-1 LGG-LGGFGGVGGTGG-QGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG
MSMEG_0868|M.smegmatis_MC2_155 DGG-LGGNGGDGVVNT-TANAANPGSATGTATGGDGGKATGTASQGGNGG
TH_3810|M.thermoresistible__bu RSGNGVFSGGGGTPSA-GFGVPTTIQFPAGSCTSRAVSREGIMPSSRAAS
MAB_4284c|M.abscessus_ATCC_199 NTGVSGAIGGSSHVGG-AINESLGGSGSVGGSTAVGGGAHTGVGGGVSTG
MAV_4827|M.avium_104 RIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQ
Rv0297|M.tuberculosis_H37Rv ----GHGGDGGSVNTPIGGSEAGDGGKGGLGGDGG---------------
Mb0305|M.bovis_AF2122/97 ----GHGGDGGSVNTPIGGSEAGDGGKGGLGGDGGDGAAGGDGGAGGDGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M ----AGGGVGGDGSSRGGIGGNGGSGANSMAIGGEGGVGGRGGDAGTSGL
MUL_3318|M.ulcerans_Agy99 ----GAGGGGGNAGQFGEPGTGGSGGNGGKGGDGAAGGNGGTGGIGGTGG
Mflv_5091|M.gilvum_PYR-GCK ----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-
Mvan_1264|M.vanbaalenii_PYR-1 ----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-
MSMEG_0868|M.smegmatis_MC2_155 PSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGV
TH_3810|M.thermoresistible__bu ------ARAGAACASSTSRSRRSFCCSRA---------------------
MAB_4284c|M.abscessus_ATCC_199 ---VGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGS
MAV_4827|M.avium_104 -----HQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVPTPGA
Rv0297|M.tuberculosis_H37Rv GRGIFGQFGAGGAGGAGGVGGAGG---------------AGGTGG-----
Mb0305|M.bovis_AF2122/97 GRGIFGQFGAGGAGGAGGVGGAGG---------------AGGTGG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M LIGNGGDGGSGGAGGTGGTGGAGG---------------AGAAGG-----
MUL_3318|M.ulcerans_Agy99 IGGDGRNGSTGAIGGNGGTGGTGG---------------TGGTGGKSLGN
Mflv_5091|M.gilvum_PYR-GCK ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-N
Mvan_1264|M.vanbaalenii_PYR-1 ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-N
MSMEG_0868|M.smegmatis_MC2_155 ATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVGG-------------GAHTGVGGGVNTG
MAV_4827|M.avium_104 GGSGGSGGGHVPTPGTGGPGGTGG----------------SGGGHVPTPG
Rv0297|M.tuberculosis_H37Rv ---GGGNGGAIFNAG-TPGAAG---------TGGDGGVGGTG--------
Mb0305|M.bovis_AF2122/97 ---GGGNGGAIFNAG-TPGAAG---------TGGDGGVGGTG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M ---AGGNGSTQIAFGGDGGNGG---------DGGDGAQGGEGGATGSVGG
MUL_3318|M.ulcerans_Agy99 LPSGDGGVGGNAGTGGNGGNAT---------DGGAGGKGGDGAAGGTGGN
Mflv_5091|M.gilvum_PYR-GCK GANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGA
Mvan_1264|M.vanbaalenii_PYR-1 GANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGA
MSMEG_0868|M.smegmatis_MC2_155 GGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGD
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGVGSHVGGGISESLGGSGSVG-------GSTAVGGGAHTSAINDALGGS
MAV_4827|M.avium_104 AGTPGGSGGGHLPFPGAGSTPG---------GSGGGHLPTPGAG------
Rv0297|M.tuberculosis_H37Rv ------------------AAGGKGGAGGSGGVNGA--------TGADGAK
Mb0305|M.bovis_AF2122/97 ------------------AAGGKGGAGGSGGVNGA--------TGADGAK
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5135|M.marinum_M IGSQGGILFSHAGADGSTGAPGAGGAGGAGGAAGG--------FGAGGSG
MUL_3318|M.ulcerans_Agy99 AGEFQSLLG--------ISKGGDGGTGGDGGTGTP--------VGADGLA
Mflv_5091|M.gilvum_PYR-GCK GGAGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGG
Mvan_1264|M.vanbaalenii_PYR-1 GGAGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSVGGSTAVGGGAHTSAINESMNSSINASHSSSMN--------ESFGSSM
MAV_4827|M.avium_104 -----------------TPGGGLGGFGGGHAPAPG--------GGLGGGG
Rv0297|M.tuberculosis_H37Rv GLDGATGG----KGNNGNPG-------------------
Mb0305|M.bovis_AF2122/97 GLDGATGG----KGNNGNPG-------------------
MLBr_01183|M.leprae_Br4923 ---------------------------------------
MMAR_5135|M.marinum_M ATAGADGK----AGTAGTAGATGPHG-------------
MUL_3318|M.ulcerans_Agy99 GTGGAGGFGIFPGGQTGQNGTDSKAG-------------
Mflv_5091|M.gilvum_PYR-GCK GAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH-----
MAV_4827|M.avium_104 GHAPAPGGGLGGFGGGHSGGGLGGLGGGHK---------