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VSFVIAQPEMIAAAAGELASIRSAINAANAAAAAQTTGVMSAAADEVSTAVAALFSSHAQAYQAASAQAA AFHAQVVRTLTVDAGAYASAEAANAGPNMLAAVNAPAQALLGRPLIGNGANGAPGTGQAGGDGGLLFGNG GNGGSGAPGQAGGAGGAAGFFGNGGNGGDGGAGANGGAGGTAGWFFGFGGNGGAGGIGVAGINGGLGGAG GDGGNAGFFGNGGNGGMGGAGAAGVNAVNPGLATPVTPAANGGNGLNLVGVPGTAGGGADGANGSAIGQA GGAGGDGGNASTSGGIGIAQTGGAGGAGGAGGDGAPGGNGGNGGSVEHTGATGSSASGGNGATGGNGGVG APGGAGGNGGHVSGGSVNTAGAGGKGGNGGTGGAGGPGGHGGSVLSGPVGDSGNGGAGGDGGAGVSATDI AGTGGRGGNGGHGGLWIGNGGDGGAGGVGGVGGAGAAGAIGGHGGDGGSVNTPIGGSEAGDGGKGGLGGD GGDGAAGGDGGAGGDGGGRGIFGQFGAGGAGGAGGVGGAGGAGGTGGGGGNGGAIFNAGTPGAAGTGGDG GVGGTGAAGGKGGAGGSGGVNGATGADGAKGLDGATGGKGNNGNPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0305 | PE_PGRS5 | - | 100% (606) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb0896c | PE_PGRS15 | e-170 | 53.98% (615) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb2878 | PE_PGRS48 | e-169 | 54.44% (619) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-119 | 47.86% (537) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0297 | PE_PGRS5 | 0.0 | 97.52% (606) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-14 | 41.30% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-50 | 36.09% (460) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4270 | - | 1e-171 | 53.06% (654) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 5e-25 | 40.51% (195) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-100 | 40.71% (624) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 4e-43 | 37.95% (332) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0572 | - | 1e-158 | 48.57% (735) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-118 | 45.72% (573) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0305|M.bovis_AF2122/97 --------------------------------------------------
Rv0297|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4270|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0305|M.bovis_AF2122/97 --------------------------------------------------
Rv0297|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4270|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0305|M.bovis_AF2122/97 -----------------------------------------MS-FVIAQP
Rv0297|M.tuberculosis_H37Rv -----------------------------------------MS-FVIAQP
MLBr_01183|M.leprae_Br4923 -----------------------------------------MPLFLNAEP
MUL_0572|M.ulcerans_Agy99 -----------------------------------------MS-YVVAIP
MMAR_4270|M.marinum_M -----------------------------------------MS-FVFAVP
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAPSS
Mb0305|M.bovis_AF2122/97 ----------------------------------------EMIAAAAGEL
Rv0297|M.tuberculosis_H37Rv ----------------------------------------EMIAAAAGEL
MLBr_01183|M.leprae_Br4923 ----------------------------------------QALTAAANTL
MUL_0572|M.ulcerans_Agy99 ----------------------------------------DMLASAAADV
MMAR_4270|M.marinum_M ----------------------------------------ETMAAVTSEL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu ----------------------------------------VDGDGGSGGR
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MAV_4827|M.avium_104 ----------------------------------------IQMVVLEGEY
Mb0305|M.bovis_AF2122/97 AS---------------------------------------IRSAINAAN
Rv0297|M.tuberculosis_H37Rv AS---------------------------------------IRSAINAAN
MLBr_01183|M.leprae_Br4923 EG---------------------------------------LSAATVASN
MUL_0572|M.ulcerans_Agy99 AG---------------------------------------IGSSVGAAN
MMAR_4270|M.marinum_M AT---------------------------------------IGSNLEMAN
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu TG---------------------------------------LFSKLSRGG
MAB_4284c|M.abscessus_ATCC_199 EA-----------------------------------------ALANAGL
MAV_4827|M.avium_104 AD----------------------------------------GATVEEDA
Mb0305|M.bovis_AF2122/97 AAAAAQTTGVMSAAADEVSTAVAALFSSHAQAYQAASAQAAAFHAQVVRT
Rv0297|M.tuberculosis_H37Rv AAAAAQTTGVMSAAADEVSTAVAALFSSHAQAYQAASAQAAAFHAQVVRT
MLBr_01183|M.leprae_Br4923 AAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQS
MUL_0572|M.ulcerans_Agy99 TAAVGATTGVMAAADDEVSVAIAALFSGHGQAYQAISAQAAAFHDQFLRA
MMAR_4270|M.marinum_M AAAALPTTGLLAAGADEVSAAIAALFDEHALGYQTISAQASAFHARFMSA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu DGG---DGGLGGNGGHGGGTGIISLLSLAGNGGNGGNGYRTTDN-NALDG
MAB_4284c|M.abscessus_ATCC_199 SAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQ
MAV_4827|M.avium_104 IDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAA
Mb0305|M.bovis_AF2122/97 LTVDAGAYASAEAAN------AGPNMLAAVNAPAQALLGRPLIGNGANGA
Rv0297|M.tuberculosis_H37Rv LTVDAGAYASAEAAN------AGPNMLAAVNAPAQALLGRPLIGNGANGA
MLBr_01183|M.leprae_Br4923 LLTSSSAYAGTETAN------HDS--L-----------------------
MUL_0572|M.ulcerans_Agy99 LTGAGGAYAAAEAANASPLQAAEQEVLAVINAPTNALLGRPLIGNGTDGL
MMAR_4270|M.marinum_M LNTGAGAYAAAEAANSSPLQALQDLTLNAINAPAQSLFGRPLIGDGAN-A
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GHGGNGGNVGFFSLFN----------------------------------
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MAV_4827|M.avium_104 ALRDALAARRIDNVMLVS-AFLAAAALAQNVGGAMGYERTAVLLVEPDTA
Mb0305|M.bovis_AF2122/97 PGTGQAGGDGGLLFGNGGNGGSGAPGQAGGAGGAA---------------
Rv0297|M.tuberculosis_H37Rv PGTGQAGGDGGLLFGNGGNGGSGAPGQAGGAGGAA---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 AGTGAAGGAGGLLWGNGGNGGSGAAGQAGGAGGAA---------------
MMAR_4270|M.marinum_M TTPGGNGGAGGILWGNGGAGATGAAGQTGGNGGAA---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu ------------LGGAGGWGGSGVDGVDVVGGNPD---------------
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSG---------------
MAV_4827|M.avium_104 TLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAM---------------
Mb0305|M.bovis_AF2122/97 -GFFGNGGNGGDGGAG--------ANGGAGGTAG----------------
Rv0297|M.tuberculosis_H37Rv -GFFGNGGNGGDGGAG--------ANGGAGGTAG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 -GLIGTGGAGGMGGAGG-------GAGGMGGSGG----------------
MMAR_4270|M.marinum_M -GFIGNGGAGGAGGAG--------ATGGVGGSGG----------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu --------------------------GGTPGAHG----------------
MAB_4284c|M.abscessus_ATCC_199 -PIASGQGSTAVNGDVR-------DSNIINADHG----------------
MAV_4827|M.avium_104 --VAGLEKLESLPG------------GLLLVGSG----------------
Mb0305|M.bovis_AF2122/97 WFFGFGGNG------GAGGIGVAGING--------------GLGGAGGDG
Rv0297|M.tuberculosis_H37Rv WFFGFGGNG------GAGGIGVAGING--------------GLGGAGGDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 WLLGNGGAG------GAGGVGCAGVSG--------------GVG---GTG
MMAR_4270|M.marinum_M MLFGNGGAG------GNG--GTAMVVG--------------GTGGNGGAG
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu ------------------------------------------------ES
MAB_4284c|M.abscessus_ATCC_199 SNVGVDQSQ------TRVGGDYTNVSG----------------HGSADID
MAV_4827|M.avium_104 ----VDVAPLKQVLQTTTFLDVSVAEE-----------------PETALA
Mb0305|M.bovis_AF2122/97 GNAGFFGNGGNG--------------GMGGAGAAGVNAVNPGLATPVTP-
Rv0297|M.tuberculosis_H37Rv GNAGFFGNGGNG--------------GMGGAGAAGVNAVNPGLATPVTP-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GNAMLFGNGGAG--------------GMGGAGADGAVGAAGTAGTSTSAG
MMAR_4270|M.marinum_M GSAGLFGAGGAG--------------GQGGQGAQGPDAVNPGPVSPTGQA
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu HTPGVYTD---------------------RQGEDGEDGTGTGIG------
MAB_4284c|M.abscessus_ATCC_199 KSVTVVDDHSQR--------------NTTNINDSFNTDRSTNIGSGNTTN
MAV_4827|M.avium_104 RGAALAAANAPL---------------FASSTAALAYAQDPGTGAVDQYS
Mb0305|M.bovis_AF2122/97 ------------------------------------AANGGNGLNLVGVP
Rv0297|M.tuberculosis_H37Rv ------------------------------------AANGGNGLNLVGVP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GVGGAGWDATAAGVLAATGGDGGDSGGGGAGGNGGAGGAGGHGSALFGAD
MMAR_4270|M.marinum_M TSGTGG----------------------------GVGENGGPGDSSTVTG
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGG--------------VGGIGGAGSTGAVGGVGGKG----IQG
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGG--------------VGGVGGVGATGGAGGVGGKG----IQG
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATG--------------ISAGGDGGSATGADSLGGRGGTSWVQA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------TEIGSHNQANIGTS
MAV_4827|M.avium_104 -------------------------------------LPDYLYVPVDPEP
Mb0305|M.bovis_AF2122/97 GTA----------------GGGADGANGSAIG------------------
Rv0297|M.tuberculosis_H37Rv GTA----------------GGGADGANGSAIG------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GAN----------------GNGGAGGAGGNPG------------------
MMAR_4270|M.marinum_M EEG----------------GDGGSGGQGSPGA------------------
Mflv_5091|M.gilvum_PYR-GCK GQG-------------LQGGKGGDGGAGGKGGDADSMGS-----------
Mvan_1264|M.vanbaalenii_PYR-1 GQG-------------LQGGQGGDGGTGGTGGDATSMGE-----------
MSMEG_0868|M.smegmatis_MC2_155 GYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTA
TH_3810|M.thermoresistible__bu -------------------GRGGNGGS-----------------------
MAB_4284c|M.abscessus_ATCC_199 TSAG---------------GSAAVGGNAGLAGNAG---------------
MAV_4827|M.avium_104 GDDE--------------LAYSAVGEEDAESP------------------
Mb0305|M.bovis_AF2122/97 -------QAG--GAGGDGGNASTSGGIG----------------------
Rv0297|M.tuberculosis_H37Rv -------QAG--GAGGDGGNASTSGGIG----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 -------APGNGGTGGVGPDAATSGGMGGTGGDPGAVGGRGNSGAAGGAG
MMAR_4270|M.marinum_M -------STASGGTGGDGGLAGDG--------------------------
Mflv_5091|M.gilvum_PYR-GCK -------AGATGGKGGNGGNGGRGGLFG----------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------AGATGGKGGNGGNGGRGSLFG----------------------
MSMEG_0868|M.smegmatis_MC2_155 IGGNGGAASANGAVGGNGGFTNIAAIHGS---------------------
TH_3810|M.thermoresistible__bu -------SSGTHPMAEDGEHVKALD-------------------------
MAB_4284c|M.abscessus_ATCC_199 -------LAGNAGLAGNAGLAGNAGLAG----------------------
MAV_4827|M.avium_104 -----TVVIEKLFLPEDSEPRRRPVLLVG---------------------
Mb0305|M.bovis_AF2122/97 ------------IAQTGGAGGAG---------------------------
Rv0297|M.tuberculosis_H37Rv ------------IAQTGGAGGAG---------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 AVAGASGAAGTIIAGNGGNGGAGGAGYAADGPAGPAIGNGGDGGHGGAGG
MMAR_4270|M.marinum_M --------------GPGAPGGTG---------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------KGGNAGNGAD-------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------RGGNAGNGGN-------------------------
MSMEG_0868|M.smegmatis_MC2_155 -ITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGK-----
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------NAGLAGNAG--------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0305|M.bovis_AF2122/97 --GAGGDGAPGGNGGNGGSVEHTGATG---------------SSASGGNG
Rv0297|M.tuberculosis_H37Rv --GAGGDGAPGGNGGNGGSVEHTGATG---------------SSASGGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 FYGNGGAGGAGGNSAPGGGTGGNGGTGGD-------------SGAMGSSG
MMAR_4270|M.marinum_M --GGGGNGGAGANNFSGGSATSGGAGG---------------NGNNGGTG
Mflv_5091|M.gilvum_PYR-GCK ----GGTGGAGGAGGTGG-TGGAGGTGG-----------------TGGTG
Mvan_1264|M.vanbaalenii_PYR-1 ----GGTGGNGGNGGTGG-TGGNGGTGG-----------------TGGTG
MSMEG_0868|M.smegmatis_MC2_155 --AAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNG
TH_3810|M.thermoresistible__bu ----GRPGLDGGNGSHGG---------------------------NGGHG
MAB_4284c|M.abscessus_ATCC_199 ---LAGNAGLAGNAGLAGNAGLAGNAG------------------LAGNA
MAV_4827|M.avium_104 ----SGLAVVGISAVLALEIALAIGIR------------------TTGTV
Mb0305|M.bovis_AF2122/97 ATGGNGGVGAPGGAGGNGGHVS-------------GGSVNTAGAGGKGGN
Rv0297|M.tuberculosis_H37Rv ATGGNGGVGAPGGAGGNGGHVS-------------GGSVNTAGAGGKGGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GRGGDGGVGTNGGAGGGGGNATSYGTANATGGAGGDGGTGSTGNGGSGGD
MMAR_4270|M.marinum_M GDGAAGGDGGNGGNGGSGGTTTSKVSN--------AGSGANGGDGGDGGD
Mflv_5091|M.gilvum_PYR-GCK GIGGAGSTGGTGGTGGTGGTGGTGGTG---------GTGGTGGTGGTGGK
Mvan_1264|M.vanbaalenii_PYR-1 GIGGAGSTGGTGGTGGTGGTGGTGGTG---------GTGGTGGTGGTGGK
MSMEG_0868|M.smegmatis_MC2_155 GRGGDGGTFVNAGANGNGGAGGAGGVSE--------GEGGTGGHGGDGGR
TH_3810|M.thermoresistible__bu GRGGFLGIGGSGGWGGHGGNGG-----------------DTDADGGNGGD
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAGN------------AGLAGNAGLAGNAGL
MAV_4827|M.avium_104 ALQPTPNQHLIVPTEQAPAPPPVQASAP--------QPKISVPEPVAAPK
Mb0305|M.bovis_AF2122/97 GGTGGAGGPGGHG----------GSVLSGPVG-------DSGNGGAGGDG
Rv0297|M.tuberculosis_H37Rv GGTGGAGGPGGHG----------GSVLSGPVG-------DSGNGGAGGDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GGNGGTGHGGGGGPGGTAINYGAGDAFGGAAG-------KGGTGVVGGNG
MMAR_4270|M.marinum_M GGAGAVGGNGGNG--GKGGDSGSGGFFTPSPG-------TGGAGGDGGHG
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
TH_3810|M.thermoresistible__bu GGNGGSAGRGGTG---------------GLRG---------VFGINGGNG
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAG----------NAAVAGNA
MAV_4827|M.avium_104 PLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPP-------VVPVPVVVPPV
Mb0305|M.bovis_AF2122/97 GAG------------------------------VSATDIAGTGG----RG
Rv0297|M.tuberculosis_H37Rv GAG------------------------------VSATDIAGTGG----RG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GSGGAAYNYGTGNATGAGGSSGSGGAASVPNSASTATATSGSGG----AG
MMAR_4270|M.marinum_M GSG-------------------------------SNGQAGGSGG----QG
Mflv_5091|M.gilvum_PYR-GCK GAG------------------------------DGTGGTGGTGG----TG
Mvan_1264|M.vanbaalenii_PYR-1 GAG------------------------------DGLGGTGGTGG----TG
MSMEG_0868|M.smegmatis_MC2_155 GAGRIRVNNGTA-------------------TGTATGGNGGNGGNGDADG
TH_3810|M.thermoresistible__bu RAG---------------------------------------------LG
MAB_4284c|M.abscessus_ATCC_199 AVG-------------------------------GVLNTGVSG----AIG
MAV_4827|M.avium_104 PVP-------------------------------VPVRIPVPDP----VS
Mb0305|M.bovis_AF2122/97 GNGGHGG-----------------LWIGNGGDGGAGGVGGVGGAG-----
Rv0297|M.tuberculosis_H37Rv GNGGHGG-----------------LWIGNGGDGGAGGVGGVGGAG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 GDGTDGGNGGSGGFAFTFGTGNIIAGVGGGGGTGSTGVGGIGGSGGGADI
MMAR_4270|M.marinum_M GAGGNGG-----------------LLAGDGGAGGAGGLGGQGGAAAAG--
Mflv_5091|M.gilvum_PYR-GCK GQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1 GFGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG-----
MSMEG_0868|M.smegmatis_MC2_155 HRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATI
TH_3810|M.thermoresistible__bu GRGX---------------------------XXXGGGVGAAVRSG-----
MAB_4284c|M.abscessus_ATCC_199 GSSHVGG-------------------AINESLGGSGSVGGSTAVG-----
MAV_4827|M.avium_104 PPQLLAP----------------------PRLSVPQPVQPPVRVP-----
Mb0305|M.bovis_AF2122/97 ------------------------AAGAIGGHGGDGGSVN--------TP
Rv0297|M.tuberculosis_H37Rv ------------------------AAGAIGGHGGDGGSVN--------TP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 ----------------NNGAFTVVPQGGAGGHGGDGATDGGAGGAGGFTE
MMAR_4270|M.marinum_M ------------------------ANGGVAGNGGNGGHGPFG-----EKI
Mflv_5091|M.gilvum_PYR-GCK ------------------GQGGTGGTGGQGGTGGTGGTGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------GTGGTGGTGGQGGTGGTGGTGGTG--------
MSMEG_0868|M.smegmatis_MC2_155 VAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGI
TH_3810|M.thermoresistible__bu -------------------------NGVFSGGGGTP--------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------GGAHTGVGGGVSTGVG---------
MAV_4827|M.avium_104 ------------------------QPPSPPQVGGTVPQSPPQ-------H
Mb0305|M.bovis_AF2122/97 IGGSEAGDGGKGGLGGDGGDGAAGGDGGAGGDGGGRGIFGQFG-------
Rv0297|M.tuberculosis_H37Rv IGGSEAGDGGKGGLGGDGG---------------GRGIFGQFG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 IDSSASVIAATGGAGGDGGSGGTGRGGTGGGGTGGGGTGGGGG-------
MMAR_4270|M.marinum_M PAGGSGGDGGTGGIGGDGGLGGDGGAGGQGGAGGRAGLLAGLGG------
Mflv_5091|M.gilvum_PYR-GCK GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGT
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGV
MSMEG_0868|M.smegmatis_MC2_155 GAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -VGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVG-------
MAV_4827|M.avium_104 QTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGGGHVPTPG-------
Mb0305|M.bovis_AF2122/97 ---------------AGGAGGAG----GVGGAGGAGGTGGGGGNG-----
Rv0297|M.tuberculosis_H37Rv ---------------AGGAGGAG----GVGGAGGAGGTGGGGGNG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 ---------------VGINNGSGEAIGGAPGAGGTGAVGGDGGQG-----
MMAR_4270|M.marinum_M ---------------AGGDGGLG----GNGGVGGDGAQGGLGGNG-----
Mflv_5091|M.gilvum_PYR-GCK AGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG-----
Mvan_1264|M.vanbaalenii_PYR-1 AGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG-----
MSMEG_0868|M.smegmatis_MC2_155 ASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALV
TH_3810|M.thermoresistible__bu ----------------------------SAGFGVPTTIQFPAGSC-----
MAB_4284c|M.abscessus_ATCC_199 ---------------VGSHVGGG----ISESLGGSGSVGGSTAVG-----
MAV_4827|M.avium_104 ---------------AGGSGGSGGGHVPTPGTGGPGGTGGSGGGH-----
Mb0305|M.bovis_AF2122/97 ----------GAIFNAGTPGAAGTGGDGGVGG---------------TGA
Rv0297|M.tuberculosis_H37Rv ----------GAIFNAGTPGAAGTGGDGGVGG---------------TGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 ----------GAAYSYGTGDATGSAGAAGTAG---------------TTG
MMAR_4270|M.marinum_M ----------GVRNSD-NLSYDGIIGNGGTGG---------------NGG
Mflv_5091|M.gilvum_PYR-GCK -AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGS
Mvan_1264|M.vanbaalenii_PYR-1 -AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGS
MSMEG_0868|M.smegmatis_MC2_155 MAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAI
TH_3810|M.thermoresistible__bu -----------------TSRAVSREGIMPSSR----------------AA
MAB_4284c|M.abscessus_ATCC_199 ----------GGAHTGVGGGVNTGVGVGSHVG------------GGISES
MAV_4827|M.avium_104 -----------VPTPGAGTPGGSGGGHLPFPG----------------AG
Mb0305|M.bovis_AF2122/97 AGGKGGAGGSGGVNG------ATGADGAKG--------LDGATGGKGNNG
Rv0297|M.tuberculosis_H37Rv AGGKGGAGGSGGVNG------ATGADGAKG--------LDGATGGKGNNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 VGGTGGAGGAAYTLNGASTATATGGIGGNG--------GDGGTANGSNGG
MMAR_4270|M.marinum_M VGGHGGDGGAGGEGGSGSLLGAAGSAGSNA--------AGGSGGTGGLRG
Mflv_5091|M.gilvum_PYR-GCK AGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGG
Mvan_1264|M.vanbaalenii_PYR-1 AGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEA
MSMEG_0868|M.smegmatis_MC2_155 SGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNG
TH_3810|M.thermoresistible__bu SARAGAACASSTSRSRRSFCCSRA--------------------------
MAB_4284c|M.abscessus_ATCC_199 LGGSGSVGGSTAVGGGAHTSAINDALGGSGS-------VGGSTAVGGGAH
MAV_4827|M.avium_104 STPGGSGGGHLPTPGAGTPGGGLGGFGGGHAP------APGGGLGGGGGH
Mb0305|M.bovis_AF2122/97 NPG-----------------------------------------------
Rv0297|M.tuberculosis_H37Rv NPG-----------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MUL_0572|M.ulcerans_Agy99 NGGAGGYASTTGT------------------GTASVGNGGRGGDGTATVA
MMAR_4270|M.marinum_M QGGDPGSTGRAGT------------------GSAG---------------
Mflv_5091|M.gilvum_PYR-GCK SG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE-------
Mvan_1264|M.vanbaalenii_PYR-1 VD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE-------
MSMEG_0868|M.smegmatis_MC2_155 TGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TSAINESMNSSIN-------------------------------------
MAV_4827|M.avium_104 APAPGGGLGGFGG-------------------------------------
Mb0305|M.bovis_AF2122/97 -------------------------------------------------
Rv0297|M.tuberculosis_H37Rv -------------------------------------------------
MLBr_01183|M.leprae_Br4923 -------------------------------------------------
MUL_0572|M.ulcerans_Agy99 TGGTGGVGGNAHAPAGSPVP-GVGGKGGNPGPGGKPGPNGADGIVV---
MMAR_4270|M.marinum_M ADGMNGTDGDPGDPGGMA-------------------------------
Mflv_5091|M.gilvum_PYR-GCK -GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD--
Mvan_1264|M.vanbaalenii_PYR-1 -GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD---
MSMEG_0868|M.smegmatis_MC2_155 AGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP--
TH_3810|M.thermoresistible__bu -------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH
MAV_4827|M.avium_104 ----GHSGGGLGGLGGGHK------------------------------