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MSYLAIAPEIVAAAAADMDGIGSPITAANAAAAIPTSAIAAAAADEISAAIAELFGNHAQQYQALSAQMA RFHDQFVRSLSGAAQTYARAEATGAAPLQPVLDLINGPTQALLGRPLIGNGTSGALGTGQAGGDGGLLIG NGTSGALGTGQAGGDGGLLIGNGGAGGSGAAGQAGGAGGAGGAAGLIGSGGAGGIGGTGAAGGKGGNAVL FGAGGNGGIGGTGAVGGTGAVGGAGGNGGFLFGHGGDGGTGGTGASAAAGANGGAGQTGLAGTDGGTGGA SGEGGAGGKGGLLFGAGGEGGAGGTGGAGGTGGAGGDGLAATTAGGTGGNAGDGGEGGAGGNAGAGGAGG QGGLFGNAGTTGAGGDGGNGGNGGLAGNGGAGGNGDASNPNGGTGGNAANPGAGGAGGAGGNGSRTGAPG TTGNTPTTAAGHGGKGGDGFNPATSGQDGGSGGKGGDAGQFGNGGNGGNGAAGDAAGSGHTGGNGGAGGG GGNAGQFGEPGTGGSGGNGGKGGDGAAGGNGGTGGIGGTGGIGGDGRNGSTGAIGGNGGTGGTGGTGGTG GKSLGNLPSGDGGVGGNAGTGGNGGNATDGGAGGKGGDGAAGGTGGNAGEFQSLLGISKGGDGGTGGDGG TGTPVGADGLAGTGGAGGFGIFPGGQTGQNGTDSKAG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_3318 | - | - | 100% (667) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_0572 | - | e-167 | 48.95% (760) | PE-PGRS family protein |
M. ulcerans Agy99 | MUL_2354 | - | e-161 | 48.40% (686) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1487c | PE_PGRS28 | 0.0 | 51.26% (751) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-133 | 47.86% (631) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3345c | PE_PGRS50 | 0.0 | 52.22% (743) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 3e-12 | 38.20% (89) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 4e-56 | 29.38% (633) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_2033 | - | 0.0 | 81.31% (674) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 4e-24 | 38.07% (197) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-107 | 37.23% (838) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 3e-43 | 40.41% (292) | PUTATIVE - |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-131 | 44.64% (690) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M -------------------------------------------------- Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 ------------------MSYLAIAPEIVAAAAADMDGIGSPIT------ MMAR_2033|M.marinum_M ------------------MSYLAIAPEIVAAAAADMDGIGSAIT------ Mb1487c|M.bovis_AF2122/97 ------------------MSLVIVAPETVAAAALDVARIGSSIG------ Rv3345c|M.tuberculosis_H37Rv -----------------MVMSLMVAPELVAAAAADLTGIGQAIS------ Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------MSIIDFILNLFRDPVEAASYVADPEAALANAG------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------MNIVLGVSMAPSSIQMVVLEGEYADG----- MUL_3318|M.ulcerans_Agy99 ---------------------------------------AANAAAAIPTS MMAR_2033|M.marinum_M ---------------------------------------AANAAAAIPTS Mb1487c|M.bovis_AF2122/97 ---------------------------------------VANSAAAGSTT Rv3345c|M.tuberculosis_H37Rv ---------------------------------------AANAAAAGPTT Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------LSAVSAAQVGAV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------------------------------ATVEEDAIDVT MUL_3318|M.ulcerans_Agy99 AIAAAAADEISAAIAELFGNHAQQYQALSAQMARFHDQFVRSLSGAAQTY MMAR_2033|M.marinum_M AIAAAAADEISAAIAELFGNHAQQYQALSAQIARFHDQFVRSLSGAAQTY Mb1487c|M.bovis_AF2122/97 SVLAAGADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSY Rv3345c|M.tuberculosis_H37Rv QVLAAAGDEVSAAIAALFGTHAQEYQALSARVATFHEQFVRSLTAAGSAY Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 MPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRD MUL_3318|M.ulcerans_Agy99 AR------------------------AEATGAAPLQP----VLDLINGPT MMAR_2033|M.marinum_M AS------------------------AEATGAAPLQP----VLDLINGPT Mb1487c|M.bovis_AF2122/97 VS------------------------AEATNAAPLATLEHNVLNALNAPT Rv3345c|M.tuberculosis_H37Rv AT------------------------AEAANASPLQALEQQVLGAINAPT Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu ---------------------------------------------VD--- MAB_4284c|M.abscessus_ATCC_199 LS------------------------PRDNDFLSHNDTDFASHNPIASGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ALAAR----------------------RIDNVMLVSAFLAAAALAQNVGG MUL_3318|M.ulcerans_Agy99 QA---LLGRPLIGNGTSGALGTGQAGGDGGLLIGNGTSGALG-----TGQ MMAR_2033|M.marinum_M QA---LLGRPLIGN---------------------GASGAPG-----TGQ Mb1487c|M.bovis_AF2122/97 QA---LLGRPLIGD---------------------GAAGAPG-----TGQ Rv3345c|M.tuberculosis_H37Rv QL---WLGRPLIGD---------------------GVHGAPG-----TGQ Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGN---------------------GGSGWNSDVVGMDGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGN---------------------GGSGWNSEIAGVSGG MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGD---------------------GGHGYDGSAAGLAGG TH_3810|M.thermoresistible__bu ------------GD----------------------------------GG MAB_4284c|M.abscessus_ATCC_199 QVMSPSGNVDSFNR----------------------GPLLDLSFGDLQFG MLBr_01183|M.leprae_Br4923 --------MPLFLN------------------------------------ MAV_4827|M.avium_104 AMGYERTAVLLVEP-------------------------DTATLAVVETS MUL_3318|M.ulcerans_Agy99 AGGDGGLLIG--NGGAGGSGAAGQAGGAGGAGGAAGLIGSGGAGGIGGTG MMAR_2033|M.marinum_M AGGDGGLLIG--NGGAGGSGAAGQAGGAG---GAAGLIGSGGAGGIGGTG Mb1487c|M.bovis_AF2122/97 AGGAGGILWG--NGGAGGSGAPGQVGGAG---GAAGLFGTGGAGGAGGAG Rv3345c|M.tuberculosis_H37Rv PGGAGGLLWG--NGGNGGSGAAGQVGGPG---GAAGLFGNGGSGGSGGAG Mflv_5091|M.gilvum_PYR-GCK NGGNGGLFGG--NGGNGGNGLGGGNGGNGGNAGAFALFGNGGNGGNGGVG Mvan_1264|M.vanbaalenii_PYR-1 NGGNAGLFGG--NGGNGGNGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVG MSMEG_0868|M.smegmatis_MC2_155 NGGNAGLFG---NGGNGGVGWAGLDGGNGGSGG--LLMGIGGAGGAGGVG TH_3810|M.thermoresistible__bu SGGRTGLFSKLSRGGDGGDGGLGGNGGHGGGTGIISLLSLAGNGGNGGNG MAB_4284c|M.abscessus_ATCC_199 NRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVG MLBr_01183|M.leprae_Br4923 -AEPQALTAA----ANTLEGLSAATVASN--AAAAQLTTEIAPPAADDVS MAV_4827|M.avium_104 DGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDV : . . MUL_3318|M.ulcerans_Agy99 AAGGKG-------------------------------------------- MMAR_2033|M.marinum_M AAGGKG-------------------------------------------- Mb1487c|M.bovis_AF2122/97 AAGGAGGSGGWLLGNGGVGGAGGQSLLGGATG------------------ Rv3345c|M.tuberculosis_H37Rv AAGGVGGSGGWLNGNGGAGGAGGTGANGGAGGNAWLFGAGGSGGAGTNGG Mflv_5091|M.gilvum_PYR-GCK VVGATGAVG--APGVAGATGATGVTSGVVGGNGEDAVGYG---------- Mvan_1264|M.vanbaalenii_PYR-1 IAGATGAVG--APGVAGATGATGVTSNVTGGNGADAVGYG---------- MSMEG_0868|M.smegmatis_MC2_155 ADGTSAHVDGGTGGTGGTGGGTGGTGGIGGTGGGLFGLLG---------- TH_3810|M.thermoresistible__bu YRTTDN-------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHS---------------- MLBr_01183|M.leprae_Br4923 IL------------------------------------------------ MAV_4827|M.avium_104 APLKQVLQT----------------------------------------- MUL_3318|M.ulcerans_Agy99 ---------------------------GNAVLFGAGGNGGIG-------- MMAR_2033|M.marinum_M ---------------------------GNAVLFGAGGNGGIG-------- Mb1487c|M.bovis_AF2122/97 ------------------------GAGGNAGLFGVGGTGGP--------- Rv3345c|M.tuberculosis_H37Rv VGGSGGFVYGNGGAGGIGGIGGIGGNGGDAGLFGNGGAGGAGAAGLPGAA Mflv_5091|M.gilvum_PYR-GCK ----------------------ATGAAGAAGAAGAAGAAG---------- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------ATGAAGAAGAAGAAGKAG---------- MSMEG_0868|M.smegmatis_MC2_155 ----------------------HSGSTGAAGAAGNGGDGGNGGFGYVLIA TH_3810|M.thermoresistible__bu ----------------------------NALDGGHGGNGG---------- MAB_4284c|M.abscessus_ATCC_199 -------------------------QRNTTNINDSFNTDRSTN------- MLBr_01183|M.leprae_Br4923 ----------------------------LAHFFS--GHGR---------- MAV_4827|M.avium_104 ------------------------TTFLDVSVAEEPETALAR-------- . MUL_3318|M.ulcerans_Agy99 ----GTGAVGGTGAVGGAGGNGGFLFGHGGDGGTGGTGAS---------- MMAR_2033|M.marinum_M ----GTGAVGGTGAAGGAGGNGGFLFGHGGDGGTGGTGAS---------- Mb1487c|M.bovis_AF2122/97 ---GGPGGPGGVGGTGGAGGLGGTLYGAGGHGGAGGPGP----------- Rv3345c|M.tuberculosis_H37Rv GLNGGDGSDGGNGGTGGNGGRGGLLVGNGGAGGAGGVGGDGGKGGAGDPS Mflv_5091|M.gilvum_PYR-GCK ----AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------- Mvan_1264|M.vanbaalenii_PYR-1 ----AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------- MSMEG_0868|M.smegmatis_MC2_155 GPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGG TH_3810|M.thermoresistible__bu ----NVGFFS--------------LFNLGGAGGWGG-------------- MAB_4284c|M.abscessus_ATCC_199 ---IGSGNTTNTEIGSHNQANIGTSTSAGGSAAVGGNAG----------- MLBr_01183|M.leprae_Br4923 ----QYQAHASQGATNHQDLIQSLLTSSSAYAGTETANH----------- MAV_4827|M.avium_104 ----GAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLP---------- . .. MUL_3318|M.ulcerans_Agy99 -------AAAGANGG----------------------------------- MMAR_2033|M.marinum_M -------GVAGANGG----------------------------------- Mb1487c|M.bovis_AF2122/97 ------IGGVGGHGG------VGGAAGLLG-------------------- Rv3345c|M.tuberculosis_H37Rv FAVNNGAGGNGGHGGNPGVGGAGGAGGLLAGAHGAAGATPTSGGNGGDGG Mflv_5091|M.gilvum_PYR-GCK -----AVGAAGAAG------------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 -----AIGTAGVAG------------------------------------ MSMEG_0868|M.smegmatis_MC2_155 TVDGHAIGGNGGNGGNGS-------------------------------- TH_3810|M.thermoresistible__bu ---------SGVDG------------------------------------ MAB_4284c|M.abscessus_ATCC_199 -----LAGNAGLAGN----------------------------------- MLBr_01183|M.leprae_Br4923 ---------DSL-------------------------------------- MAV_4827|M.avium_104 ---------DYLYVP----------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------AGQTGLAG----------- MMAR_2033|M.marinum_M -------------------------------AGQTGLAG----------- Mb1487c|M.bovis_AF2122/97 ----------VGGHGGAGGHG------AAGIAGAAGKGG----------- Rv3345c|M.tuberculosis_H37Rv IGATANSPLQAGGAGGNGGHGGLVGNGGTGGAGGAGHAGSTGATGTA--- Mflv_5091|M.gilvum_PYR-GCK ---------------------------TVGTAGATGGTG----------- Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------AAGTAGATGGTG----------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------TTAAGGNGGTGGTGRVIAEGTGSTA TH_3810|M.thermoresistible__bu -------------------------------VDVVGGNP----------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------AGLAGNAG----------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------------VDPEPGDDE----------- MUL_3318|M.ulcerans_Agy99 ---TDGGTGGASGEGGAGGKGGLLF----------GAGGEGGAGGTGGAG MMAR_2033|M.marinum_M ---TDGGTG---GVGGAGGKGGLLF----------GAGGEGGAGGTGGAG Mb1487c|M.bovis_AF2122/97 -IFPDGSNGGAGGDAGDGGTGGRGG----------WLAGAGGAGGDGGIG Rv3345c|M.tuberculosis_H37Rv -LQPTGGNGTNGGAGGHGGNGGNGG----------AQHGDGGVGGKGGAG Mflv_5091|M.gilvum_PYR-GCK ----TGANGGAGGVGGVGGTGAAG--------------AAGGAGGLGETG Mvan_1264|M.vanbaalenii_PYR-1 ----VGGNGGAGQAGGIGGTGAAG--------------AAGQAGTAGETG MSMEG_0868|M.smegmatis_MC2_155 EGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDG TH_3810|M.thermoresistible__bu -------DGGTPGAHGESHTPGVYT---------------DRQGEDGEDG MAB_4284c|M.abscessus_ATCC_199 ----LAGNAGLAGNAGLAGNAGLAG-------------NAGLAGNAGLAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --LAYSAVGEEDAESPTVVIEKLFLP------------EDSEPRRRPVLL MUL_3318|M.ulcerans_Agy99 GTGGAGGDGLAATTAGGTGGNAGDGGEGGAGGNAGAGGAGGQG--GLFGN MMAR_2033|M.marinum_M GAGGTGGDGLAATTAGGTGGNAGDGGGGGTGGNAGDGGAGGQG--GLFGN Mb1487c|M.bovis_AF2122/97 GTGGAGGAGFSRALIVA-GDNGGDGGNGGMGGAGGAGGPGGAG--GLISL Rv3345c|M.tuberculosis_H37Rv GSGGAGGNGFDAATLGSPGADGGMGGNGGKGGDGGKAGDGGAGAAGDVTL Mflv_5091|M.gilvum_PYR-GCK TTGGAG--GVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQG Mvan_1264|M.vanbaalenii_PYR-1 VTGGVG--GIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQG MSMEG_0868|M.smegmatis_MC2_155 GTGGAG--GMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQA TH_3810|M.thermoresistible__bu TGTGIG----------------GRGGNGGSSSGTHPMAEDG--------- MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGN--AGLAGNAGLAGNAGLAGNAGLAGNAGLAG------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVP------- MUL_3318|M.ulcerans_Agy99 AGT---------------TGAGGDGGNGGNGG------------------ MMAR_2033|M.marinum_M AGT---------------TGAGGDGGNGGNGG------------------ Mb1487c|M.bovis_AF2122/97 LGG---------------QGAGGDGGDGGAGG------------------ Rv3345c|M.tuberculosis_H37Rv AVN---------------QGAGGDGGNGGEVG------------------ Mflv_5091|M.gilvum_PYR-GCK GQG-------------LQGGKGGDGGAGGKGGDADSMGS----------- Mvan_1264|M.vanbaalenii_PYR-1 GQG-------------LQGGQGGDGGTGGTGGDATSMGE----------- MSMEG_0868|M.smegmatis_MC2_155 GYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTA TH_3810|M.thermoresistible__bu -----------------EHVKALDGRPGLDGG------------------ MAB_4284c|M.abscessus_ATCC_199 -----------------NAGLAGNAGLAGNAG------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------TEQAPAPPPVQASAPQPK---------------- MUL_3318|M.ulcerans_Agy99 -------LAGNGGAGGNGDASNPN-------------------------- MMAR_2033|M.marinum_M -------LAGNGGAGGNGDASNPN-------------------------- Mb1487c|M.bovis_AF2122/97 -------VGGDRGAG-ANGNQAVN-------------------------- Rv3345c|M.tuberculosis_H37Rv -------VGGKGGAGGVSANPALNGSAGANGTAPTSGGNGGNGGAGATPT Mflv_5091|M.gilvum_PYR-GCK -------AGATGGKGGNGGNGGRGGLFG---------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------AGATGGKGGNGGNGGRGSLFG---------------------- MSMEG_0868|M.smegmatis_MC2_155 IGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGG--------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------LAGNAGLAGNAGLAGNAAVAG---------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------ISVPEPVAAPKPLSPPVAAPLP--------------------- MUL_3318|M.ulcerans_Agy99 --------GGTGGNAAN----------------------PGAGGAGGAGG MMAR_2033|M.marinum_M --------GGTGGNGAN----------------------PGAGGAGGAGG Mb1487c|M.bovis_AF2122/97 -----AGAGGAGGHGGD----------------------PGAGGAGGTGG Rv3345c|M.tuberculosis_H37Rv VAGENGGAGGNGGHGGS----------------------VGNGGAGGAGG Mflv_5091|M.gilvum_PYR-GCK -------KGGNAGNGAD----------------------GGTGGAGGAGG Mvan_1264|M.vanbaalenii_PYR-1 -------RGGNAGNGGN----------------------GGTGGNGGNGG MSMEG_0868|M.smegmatis_MC2_155 -----AAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNG TH_3810|M.thermoresistible__bu ----------NGSHGGN----------------------GGHGGRGGFLG MAB_4284c|M.abscessus_ATCC_199 ----------NAAVAGN-------------------AAVAGNAAVGGVLN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------AAPPPAAPP---------------------LPEAPPIPAAPP MUL_3318|M.ulcerans_Agy99 NGSR---------------TGAPGTTGNTPTT-------------AAGHG MMAR_2033|M.marinum_M NGSR---------------TGAPGTTGNTPTT-------------AAGHG Mb1487c|M.bovis_AF2122/97 AGST---------------IGAHGAAGASPTS--------------GGNG Rv3345c|M.tuberculosis_H37Rv NGVAGTGLALNGGNGGNGGIGGNGGSAAGTGGDGG----------KGGNG Mflv_5091|M.gilvum_PYR-GCK TGG----------------TGGAGGTGG-----------------TGGTG Mvan_1264|M.vanbaalenii_PYR-1 TGG----------------TGGNGGTGG-----------------TGGTG MSMEG_0868|M.smegmatis_MC2_155 TGGA---------------TGGRGGDGAGASVWKANGQHSTGQTDTGGNG TH_3810|M.thermoresistible__bu IGGS------------------------------------------GGWG MAB_4284c|M.abscessus_ATCC_199 TGVSG-------------AIGGSSHVGGAINES------------LGGSG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VVPVP--------------VVVPPVPVPVPVR-------------IPVPD MUL_3318|M.ulcerans_Agy99 GKGGDGFNPAT--------------------------------------- MMAR_2033|M.marinum_M GKGGDGFSPAT--------------------------------------- Mb1487c|M.bovis_AF2122/97 GAGGNGAHFSS------------------GGK------------------ Rv3345c|M.tuberculosis_H37Rv GAGANGQDFSASANGANGGQGGNGGNGGIGGKGGDAFATFAKAGNGGAGG Mflv_5091|M.gilvum_PYR-GCK GIGGAGSTGGTGGTGGTGG------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GIGGAGSTGGTGGTGGTGG------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GRGGDGGTFVNAGANGNGG------------------------------- TH_3810|M.thermoresistible__bu GHGGNG-------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SVGGSTAVGGGAHTG----------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PVSPPQLLAPPRLS------------------------------------ MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M -------------------------------------------------- Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv NGGNVGVAGQGGAGGKGAIPAMKGATGADGTAPTSGGDGGNGGNGASPTV Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 SGQDGGSG-GKGGDAGQFGNGGNGGNG---AAGDAAG----SGHTGGNGG MMAR_2033|M.marinum_M SGQDGGSG-GKGGDAGRFGNGGNGGNGGNGAAGDAAG----SGHTGGNGG Mb1487c|M.bovis_AF2122/97 AGGNGGAG-GAGGHGGLVGNGGAGGAGGNGANGAAGTNASDSGAVGGKGN Rv3345c|M.tuberculosis_H37Rv AGGNGGDG-GKGGSGGNVGNGGNGGAGGNGAAGQAGTPGPTSGDSGTSGT Mflv_5091|M.gilvum_PYR-GCK TGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 AGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGG TH_3810|M.thermoresistible__bu -GDTDADG-GNGGDGGNGGSAGRGGTG---------------GLRGVFGI MAB_4284c|M.abscessus_ATCC_199 VGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGG-----GAHTGVGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGE-----GTPPKPDG MUL_3318|M.ulcerans_Agy99 AGGGG---------GNAGQFGEPGT------------GGSGGNGGKGG-- MMAR_2033|M.marinum_M AGGGG---------GNAGQFGEPGT------------GGSGGNGGKGG-- Mb1487c|M.bovis_AF2122/97 SGGNG---------GQGGAGGDGGTL-----------AGNGGAGGTGG-- Rv3345c|M.tuberculosis_H37Rv DGGAG---------GNGGAGGAGGTL-----------AGHGGNGGKGG-- Mflv_5091|M.gilvum_PYR-GCK TGGTG---------GTGGTGGTGGAG-----------DGTGGTGGTGG-- Mvan_1264|M.vanbaalenii_PYR-1 TGGTG---------GTGGTGGTGGAG-----------DGLGGTGGTGG-- MSMEG_0868|M.smegmatis_MC2_155 NGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNG TH_3810|M.thermoresistible__bu NGGNG----------------------------------RAGLGGRGX-- MAB_4284c|M.abscessus_ATCC_199 GVSTG---------VGVGSHVGGGIS-----------ESLGGSGSVGG-- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PGNYG-----------GGHVPTP---------------GAGGSGGSGG-- MUL_3318|M.ulcerans_Agy99 --DGAAG------------------------------------------G MMAR_2033|M.marinum_M --DGAAGGLAQAGGNGGEGGAGGNAGAGGLSGTGDSTGNAGTGGNGGAGG Mb1487c|M.bovis_AF2122/97 --RGADGGLGGSG---AEGANATTAGE--------------RGQDGGKGG Rv3345c|M.tuberculosis_H37Rv --NGGQGGIGGAGERGADGAGPNANGA--------------NGENGGSGG Mflv_5091|M.gilvum_PYR-GCK --TGGQGGQGGQGG------------------------------TGGTGG Mvan_1264|M.vanbaalenii_PYR-1 --TGGFGGQGGQGG------------------------------TGGTGG MSMEG_0868|M.smegmatis_MC2_155 DADGHRGGKGGDGGEALIRATVIGSNAS-------------GTATGGDGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------STAVG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------GHVPTPG MUL_3318|M.ulcerans_Agy99 NGGTGG-------------------------------------------- MMAR_2033|M.marinum_M NGGTGGDGSDGGPGGAGGKGGNSGPGGTNGTGGHGGNGGTGGDGGDGASG Mb1487c|M.bovis_AF2122/97 NGGVGGTGGN---------------------------------------- Rv3345c|M.tuberculosis_H37Rv NGGDGGAGGNGGAGGKAQA------------------------------- Mflv_5091|M.gilvum_PYR-GCK QGG-LGGGGGTG-------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 QGG-LGGVGGTG-------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NGGTLGATNGTGGAATIVA------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGAHTGVGGG---------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 AGGSGGSGGGHVP------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M VGLGKAGGTGATGGNGGNAGSGGAAGTGGTGGTNGSAGTGGTGGTGGNGG Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M AGDKGAVGDSGFAGGTGGAGGTGGNSGPGGTNGTGGHGGNGGTGGDGGDG Mb1487c|M.bovis_AF2122/97 ------------------------------------------------AV Rv3345c|M.tuberculosis_H37Rv ------------AGYTDGATGTGGDGGNGGDGGKAGDGGAGENGLNSGAM Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------YNVVQA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M ASGVGQGKAGGTGATGGNGGNAGSGGAAGTGGDASGGGTNGSAGTGGTGG Mb1487c|M.bovis_AF2122/97 APG----ANGGHGGNGGNPGFSG--------------------------- Rv3345c|M.tuberculosis_H37Rv LPGGGTVGNPGTGGNGGNGGNAG--------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------GQGGTGGTGGQGG--------------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------GTGGTGGTGGQGG--------------------------- MSMEG_0868|M.smegmatis_MC2_155 NPQASGTATDGHGGSGINGGHGG--------------------------- TH_3810|M.thermoresistible__bu -------X------------------------------------------ MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M TGGNGGDGDKGAVGDSGFAGGTGGAGGTGGNSGPGGTNGTGGHGGNGGTG Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M GDGGDGASGVGQGKAGGTGATGGSGGNAGSGGAAGTGGNGGTNGNAGTGG Mb1487c|M.bovis_AF2122/97 --------------------AGGLGGLSGDGVTR---AAQGATPD----- Rv3345c|M.tuberculosis_H37Rv --------------------VGGTGGKAGTGSLTGLDGTDGITPNGGNGG Mflv_5091|M.gilvum_PYR-GCK --------------------TGGTGGTGGTG------------------- Mvan_1264|M.vanbaalenii_PYR-1 --------------------TGGTGGTGGTG------------------- MSMEG_0868|M.smegmatis_MC2_155 --------------------NGGQGTIEANGPSA---------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 ------------------------------------------------IG MMAR_2033|M.marinum_M TGGTGGNGGDGDKGAVGDSGFAGGTGGNGGTGGNSGPGGTNGTGGHGGNG Mb1487c|M.bovis_AF2122/97 ------------------------------------------------FA Rv3345c|M.tuberculosis_H37Rv NGGNGGKGGTAGNGSGAAGGNGGNGGSGLNGGDAGNGGNGGGALNQAGFF Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ---------------------------------------------VASGI TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------V MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------------------------------TP MUL_3318|M.ulcerans_Agy99 GTGGIGGDGRNGSTGAI-GGNGGTGGTG---------------------- MMAR_2033|M.marinum_M GTGGDGGDGRNGSTGAI-GGNGGTGGTGGIGGTAGTGGTGGSAGSAGTGG Mb1487c|M.bovis_AF2122/97 DTGGKGGNGGNGANAVAPGGTGASGGAGG--------------------- Rv3345c|M.tuberculosis_H37Rv GTGGKGGNGGNGGAGMINGGLGGFGGAGGGGAVDVA-------------- Mflv_5091|M.gilvum_PYR-GCK GTGGAGGDGGLGGLGGF-GGSGGTGGQGGLGG------------------ Mvan_1264|M.vanbaalenii_PYR-1 GTGGAGGDGGLGGLGGF-GGVGGTGGQGGQGG------------------ MSMEG_0868|M.smegmatis_MC2_155 GAGGNGGDGIDGGLGGN-GGDGVVNTTANAAN------------------ TH_3810|M.thermoresistible__bu XXGGGVGAAVRSGNGVFSGGGGTP-------------------------- MAB_4284c|M.abscessus_ATCC_199 NTGVGVGSHVGGGISESLGGSGSVGGSTAVGG------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GTGGPGGTGGSGGGHVPTPGAGTPGGSGGGHLPFPG-------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M TGGNGGAGDSGASGGTGGTGGEGGAGIGGKDGGTGGTGGTGGTGGAGVVS Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M GLSAFPGGIGGAGGAGGQGGQATGGGNAGDGGTGGQGGTGGQGATSLFEA Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M SSGGTGGAGGAGGLGGQAADGGNAGDGGTGGQGGTGGQGAAGPTVNDTAG Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M DGGAGGDGGVGGAGGQGGQATDGGNAGNAGDGGNGGQGGTGGQGAAAPSA Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------GTGGTGGKSLG-- MMAR_2033|M.marinum_M AKAAGNGGAGGVGGDGGNGADASGGGNGGDGGKSGGGGTGGTGGKSLG-- Mb1487c|M.bovis_AF2122/97 -----------------------------------NAGAGGKGGENIIGD Rv3345c|M.tuberculosis_H37Rv ---------------------------------ATTGGAGGNGGAGGFAS Mflv_5091|M.gilvum_PYR-GCK ----------------------------------PGGSTGGAGGAGG--Q Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------PGGSTGGAGGAGG--Q MSMEG_0868|M.smegmatis_MC2_155 ----------------------------------PGSATGTATGGDGGKA TH_3810|M.thermoresistible__bu -------------------------------------SAGFGVPTTIQFP MAB_4284c|M.abscessus_ATCC_199 ------------------------------------GAHTSAINDALGGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------------------------AGSTPGGSGGGHLPTP MUL_3318|M.ulcerans_Agy99 NLPSGDGGVGG----NAGTG-------GNGGNATDGGAG----------- MMAR_2033|M.marinum_M NLPSGDGGVGG----NAGTG-------GNGGNATDGGAG----------- Mb1487c|M.bovis_AF2122/97 GGGGGNGGAGG----QGGD--------GTAGAGGDGGAG----------- Rv3345c|M.tuberculosis_H37Rv TGLGGPGGAGG----PGGAGDFASGVGGVGGAGGDGGAGGVGGFGGQGGI Mflv_5091|M.gilvum_PYR-GCK AGTAGKGGLFG----GSGSA-------GKAGATGAAGASG---------- Mvan_1264|M.vanbaalenii_PYR-1 AGVAGKGGLFG----GSGSA-------GTAGVTGASGASG---------- MSMEG_0868|M.smegmatis_MC2_155 TGTASQGGNGGPSWVQSGYG-------STLGGNATGTATA---------- TH_3810|M.thermoresistible__bu AGSCTSRAVSR--------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GSVGGSTAVGG--------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GAGTPGGGLGG--------------------------------------- MUL_3318|M.ulcerans_Agy99 -------GKGGDGAAGGTGGNAG--------------EFQSLLGIS---- MMAR_2033|M.marinum_M -------GKGGDGAAGGTGGNAG--------------EFQSLLGIG---- Mb1487c|M.bovis_AF2122/97 -------GKGGDGGDGGSDPTEG-------------RGFGGLGGAG---- Rv3345c|M.tuberculosis_H37Rv GGEGRTGGNGGSGGDGGGGISLGGNGGLGGNGGVSETGFGGAGGNGGYGG Mflv_5091|M.gilvum_PYR-GCK -------GKGAQGATGAQGATG------------------AQGATG---- Mvan_1264|M.vanbaalenii_PYR-1 -------GKGAQGATGAQGATG------------------AQGATG---- MSMEG_0868|M.smegmatis_MC2_155 -------GKGGEASNGGVAGNGG------------NALVMAAGTTGV--- TH_3810|M.thermoresistible__bu --------EGIMPSSRAASARAG--------------------------- MAB_4284c|M.abscessus_ATCC_199 -------GAHTSAINESMNSSIN--------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------FGGGHAPAPGGGLGGGG--------------------------- MUL_3318|M.ulcerans_Agy99 ---------KGGDGGTGGDGG---TGTPVGADGLAGTG------------ MMAR_2033|M.marinum_M ---------KGGDGGTGGDGGNGGTGTPVGAGGLAGTG------------ Mb1487c|M.bovis_AF2122/97 --------GAGGKGGAGTLLGLTVFGDNGGAGVLGDS------------- Rv3345c|M.tuberculosis_H37Rv PGGPEGNGGLGGNGGAGGNGGVSTTGGDGGAGGKGGNGGDGGNVGLGGDA Mflv_5091|M.gilvum_PYR-GCK --------ATGAAGKAGATGAAGAAGAAGSAG------------------ Mvan_1264|M.vanbaalenii_PYR-1 --------ATGASGAQGSAGSAGSAGVAGSAG------------------ MSMEG_0868|M.smegmatis_MC2_155 --------ATGNTATGGDGGAATTAGATGGAGGFSNIAA----------- TH_3810|M.thermoresistible__bu --------AACASSTSRSRRSFCCSRA----------------------- MAB_4284c|M.abscessus_ATCC_199 --------ASHSSSMNESFGSSMGSHGAAGTGFEAQG------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------GHAPAPGGGLGGFGGGHSGGGLGGLGGGHK----------- MUL_3318|M.ulcerans_Agy99 ----------------GAGGFG---------------------------- MMAR_2033|M.marinum_M ----------------GAGGFG---------------------------- Mb1487c|M.bovis_AF2122/97 ------------TDPDGSGGAG---------------------------- Rv3345c|M.tuberculosis_H37Rv GSGGAGGNGGIGTDAGGAGGAGGAGGNGGSSKSTTTGNAGSGGAGGNGGT Mflv_5091|M.gilvum_PYR-GCK --------TTGAQGSAGTNGA----------------------------- Mvan_1264|M.vanbaalenii_PYR-1 --------TTGAQGSAGTNGA----------------------------- MSMEG_0868|M.smegmatis_MC2_155 ----IHGAITDSTAISGHGGAG---------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 --IFPGGQTGQNGTDSKAG------------------------------- MMAR_2033|M.marinum_M --VFPGGQTGQNGTDGKAG------------------------------- Mb1487c|M.bovis_AF2122/97 ---GAGGAGGAGGDPTI--------------------------------- Rv3345c|M.tuberculosis_H37Rv GLNGAGGAGGAGGNAGVAGVSFGNAVGGDGGNGGNGGHGGDGTTGGAGGK Mflv_5091|M.gilvum_PYR-GCK --NGANGSQGAAGKAGATG------------------------TTGATG- Mvan_1264|M.vanbaalenii_PYR-1 --NGANGSQGAAGKAGATG------------------------TTGATG- MSMEG_0868|M.smegmatis_MC2_155 --NGGNGGKGADGWVQAYD------------------------PAGPVGS TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---HAQGHASETAHTTLPGAEHH--------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M -------------------------------------------------- Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv GGNGSSGAASGSGVVNVTAGHGGNGGNGGNGGNGSAGAGGQGGAGGSAGN Mflv_5091|M.gilvum_PYR-GCK -------AAGEDGDAGSGGSG-INGGAGGAGG------------------ Mvan_1264|M.vanbaalenii_PYR-1 -------AAGDAGDPGSEAVD-INGGAGGAGG------------------ MSMEG_0868|M.smegmatis_MC2_155 KIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSV--------WKSGGQ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M -------------------------------------------------- Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv GGHGGGATGGDGGNGGNGGNSGNSTGVAGLAGGAAGAGGNGGGTSSAAGH Mflv_5091|M.gilvum_PYR-GCK -AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GA Mvan_1264|M.vanbaalenii_PYR-1 -AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GA MSMEG_0868|M.smegmatis_MC2_155 TADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M -------------------------------------------------- Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv GGSGGSGGSGTTGGAGAAGGNGGAGAGGGSLSTGQSGGPRRQRWCRWQRR Mflv_5091|M.gilvum_PYR-GCK GGSGGSGGSGGSGGSGGAAGDSDD-------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GGSGGSGGSGGAGGSGGAAGDSD--------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGADGTPGTAGTTGANNP-------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2033|M.marinum_M -------------------------------------------------- Mb1487c|M.bovis_AF2122/97 -------------------------------------------------- Rv3345c|M.tuberculosis_H37Rv RWLGRQRRRRWCRWQRRCRRQRWRWRCRQRRLRRQWRQGRRRCRPWLHRR Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MUL_3318|M.ulcerans_Agy99 ------------------------ MMAR_2033|M.marinum_M ------------------------ Mb1487c|M.bovis_AF2122/97 ------------------------ Rv3345c|M.tuberculosis_H37Rv RGRQGRRWRQRRFQQRQRSRWQRR Mflv_5091|M.gilvum_PYR-GCK ------------------------ Mvan_1264|M.vanbaalenii_PYR-1 ------------------------ MSMEG_0868|M.smegmatis_MC2_155 ------------------------ TH_3810|M.thermoresistible__bu ------------------------ MAB_4284c|M.abscessus_ATCC_199 ------------------------ MLBr_01183|M.leprae_Br4923 ------------------------ MAV_4827|M.avium_104 ------------------------