For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. ulcerans Agy99 MUL_3318 (-)

annotation: PE-PGRS family protein
coordinates: 3690745 - 3692748
length: 667

MSYLAIAPEIVAAAAADMDGIGSPITAANAAAAIPTSAIAAAAADEISAAIAELFGNHAQQYQALSAQMA
RFHDQFVRSLSGAAQTYARAEATGAAPLQPVLDLINGPTQALLGRPLIGNGTSGALGTGQAGGDGGLLIG
NGTSGALGTGQAGGDGGLLIGNGGAGGSGAAGQAGGAGGAGGAAGLIGSGGAGGIGGTGAAGGKGGNAVL
FGAGGNGGIGGTGAVGGTGAVGGAGGNGGFLFGHGGDGGTGGTGASAAAGANGGAGQTGLAGTDGGTGGA
SGEGGAGGKGGLLFGAGGEGGAGGTGGAGGTGGAGGDGLAATTAGGTGGNAGDGGEGGAGGNAGAGGAGG
QGGLFGNAGTTGAGGDGGNGGNGGLAGNGGAGGNGDASNPNGGTGGNAANPGAGGAGGAGGNGSRTGAPG
TTGNTPTTAAGHGGKGGDGFNPATSGQDGGSGGKGGDAGQFGNGGNGGNGAAGDAAGSGHTGGNGGAGGG
GGNAGQFGEPGTGGSGGNGGKGGDGAAGGNGGTGGIGGTGGIGGDGRNGSTGAIGGNGGTGGTGGTGGTG
GKSLGNLPSGDGGVGGNAGTGGNGGNATDGGAGGKGGDGAAGGTGGNAGEFQSLLGISKGGDGGTGGDGG
TGTPVGADGLAGTGGAGGFGIFPGGQTGQNGTDSKAG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_3318--100% (667)PE-PGRS family protein
M. ulcerans Agy99MUL_0572-e-16748.95% (760) PE-PGRS family protein
M. ulcerans Agy99MUL_2354-e-16148.40% (686) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1487cPE_PGRS280.051.26% (751) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-1e-13347.86% (631) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3345cPE_PGRS500.052.22% (743) PE-PGRS family protein
M. leprae Br4923MLBr_01183-3e-1238.20% (89) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-4e-5629.38% (633) hypothetical protein MAB_4284c
M. marinum MMMAR_2033-0.081.31% (674) PE-PGRS family protein
M. avium 104MAV_4827-4e-2438.07% (197) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-1e-10737.23% (838) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-3e-4340.41% (292) PUTATIVE -
M. vanbaalenii PYR-1Mvan_1264-1e-13144.64% (690) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               --------------------------------------------------
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           ------------------MSYLAIAPEIVAAAAADMDGIGSPIT------
MMAR_2033|M.marinum_M               ------------------MSYLAIAPEIVAAAAADMDGIGSAIT------
Mb1487c|M.bovis_AF2122/97           ------------------MSLVIVAPETVAAAALDVARIGSSIG------
Rv3345c|M.tuberculosis_H37Rv        -----------------MVMSLMVAPELVAAAAADLTGIGQAIS------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------MSIIDFILNLFRDPVEAASYVADPEAALANAG------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------MNIVLGVSMAPSSIQMVVLEGEYADG-----
                                                                                      

MUL_3318|M.ulcerans_Agy99           ---------------------------------------AANAAAAIPTS
MMAR_2033|M.marinum_M               ---------------------------------------AANAAAAIPTS
Mb1487c|M.bovis_AF2122/97           ---------------------------------------VANSAAAGSTT
Rv3345c|M.tuberculosis_H37Rv        ---------------------------------------AANAAAAGPTT
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------LSAVSAAQVGAV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------------------------------------ATVEEDAIDVT
                                                                                      

MUL_3318|M.ulcerans_Agy99           AIAAAAADEISAAIAELFGNHAQQYQALSAQMARFHDQFVRSLSGAAQTY
MMAR_2033|M.marinum_M               AIAAAAADEISAAIAELFGNHAQQYQALSAQIARFHDQFVRSLSGAAQTY
Mb1487c|M.bovis_AF2122/97           SVLAAGADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSY
Rv3345c|M.tuberculosis_H37Rv        QVLAAAGDEVSAAIAALFGTHAQEYQALSARVATFHEQFVRSLTAAGSAY
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      MPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSL
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRD
                                                                                      

MUL_3318|M.ulcerans_Agy99           AR------------------------AEATGAAPLQP----VLDLINGPT
MMAR_2033|M.marinum_M               AS------------------------AEATGAAPLQP----VLDLINGPT
Mb1487c|M.bovis_AF2122/97           VS------------------------AEATNAAPLATLEHNVLNALNAPT
Rv3345c|M.tuberculosis_H37Rv        AT------------------------AEAANASPLQALEQQVLGAINAPT
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      ---------------------------------------------VD---
MAB_4284c|M.abscessus_ATCC_199      LS------------------------PRDNDFLSHNDTDFASHNPIASGN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ALAAR----------------------RIDNVMLVSAFLAAAALAQNVGG
                                                                                      

MUL_3318|M.ulcerans_Agy99           QA---LLGRPLIGNGTSGALGTGQAGGDGGLLIGNGTSGALG-----TGQ
MMAR_2033|M.marinum_M               QA---LLGRPLIGN---------------------GASGAPG-----TGQ
Mb1487c|M.bovis_AF2122/97           QA---LLGRPLIGD---------------------GAAGAPG-----TGQ
Rv3345c|M.tuberculosis_H37Rv        QL---WLGRPLIGD---------------------GVHGAPG-----TGQ
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGN---------------------GGSGWNSDVVGMDGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGN---------------------GGSGWNSEIAGVSGG
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGD---------------------GGHGYDGSAAGLAGG
TH_3810|M.thermoresistible__bu      ------------GD----------------------------------GG
MAB_4284c|M.abscessus_ATCC_199      QVMSPSGNVDSFNR----------------------GPLLDLSFGDLQFG
MLBr_01183|M.leprae_Br4923          --------MPLFLN------------------------------------
MAV_4827|M.avium_104                AMGYERTAVLLVEP-------------------------DTATLAVVETS
                                                                                      

MUL_3318|M.ulcerans_Agy99           AGGDGGLLIG--NGGAGGSGAAGQAGGAGGAGGAAGLIGSGGAGGIGGTG
MMAR_2033|M.marinum_M               AGGDGGLLIG--NGGAGGSGAAGQAGGAG---GAAGLIGSGGAGGIGGTG
Mb1487c|M.bovis_AF2122/97           AGGAGGILWG--NGGAGGSGAPGQVGGAG---GAAGLFGTGGAGGAGGAG
Rv3345c|M.tuberculosis_H37Rv        PGGAGGLLWG--NGGNGGSGAAGQVGGPG---GAAGLFGNGGSGGSGGAG
Mflv_5091|M.gilvum_PYR-GCK          NGGNGGLFGG--NGGNGGNGLGGGNGGNGGNAGAFALFGNGGNGGNGGVG
Mvan_1264|M.vanbaalenii_PYR-1       NGGNAGLFGG--NGGNGGNGLGSGDGGNGGDAGLFSLFGRGGNGGNGGVG
MSMEG_0868|M.smegmatis_MC2_155      NGGNAGLFG---NGGNGGVGWAGLDGGNGGSGG--LLMGIGGAGGAGGVG
TH_3810|M.thermoresistible__bu      SGGRTGLFSKLSRGGDGGDGGLGGNGGHGGGTGIISLLSLAGNGGNGGNG
MAB_4284c|M.abscessus_ATCC_199      NRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVG
MLBr_01183|M.leprae_Br4923          -AEPQALTAA----ANTLEGLSAATVASN--AAAAQLTTEIAPPAADDVS
MAV_4827|M.avium_104                DGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDV
                                          :            .                          .   

MUL_3318|M.ulcerans_Agy99           AAGGKG--------------------------------------------
MMAR_2033|M.marinum_M               AAGGKG--------------------------------------------
Mb1487c|M.bovis_AF2122/97           AAGGAGGSGGWLLGNGGVGGAGGQSLLGGATG------------------
Rv3345c|M.tuberculosis_H37Rv        AAGGVGGSGGWLNGNGGAGGAGGTGANGGAGGNAWLFGAGGSGGAGTNGG
Mflv_5091|M.gilvum_PYR-GCK          VVGATGAVG--APGVAGATGATGVTSGVVGGNGEDAVGYG----------
Mvan_1264|M.vanbaalenii_PYR-1       IAGATGAVG--APGVAGATGATGVTSNVTGGNGADAVGYG----------
MSMEG_0868|M.smegmatis_MC2_155      ADGTSAHVDGGTGGTGGTGGGTGGTGGIGGTGGGLFGLLG----------
TH_3810|M.thermoresistible__bu      YRTTDN--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHS----------------
MLBr_01183|M.leprae_Br4923          IL------------------------------------------------
MAV_4827|M.avium_104                APLKQVLQT-----------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           ---------------------------GNAVLFGAGGNGGIG--------
MMAR_2033|M.marinum_M               ---------------------------GNAVLFGAGGNGGIG--------
Mb1487c|M.bovis_AF2122/97           ------------------------GAGGNAGLFGVGGTGGP---------
Rv3345c|M.tuberculosis_H37Rv        VGGSGGFVYGNGGAGGIGGIGGIGGNGGDAGLFGNGGAGGAGAAGLPGAA
Mflv_5091|M.gilvum_PYR-GCK          ----------------------ATGAAGAAGAAGAAGAAG----------
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------ATGAAGAAGAAGAAGKAG----------
MSMEG_0868|M.smegmatis_MC2_155      ----------------------HSGSTGAAGAAGNGGDGGNGGFGYVLIA
TH_3810|M.thermoresistible__bu      ----------------------------NALDGGHGGNGG----------
MAB_4284c|M.abscessus_ATCC_199      -------------------------QRNTTNINDSFNTDRSTN-------
MLBr_01183|M.leprae_Br4923          ----------------------------LAHFFS--GHGR----------
MAV_4827|M.avium_104                ------------------------TTFLDVSVAEEPETALAR--------
                                                                 .                    

MUL_3318|M.ulcerans_Agy99           ----GTGAVGGTGAVGGAGGNGGFLFGHGGDGGTGGTGAS----------
MMAR_2033|M.marinum_M               ----GTGAVGGTGAAGGAGGNGGFLFGHGGDGGTGGTGAS----------
Mb1487c|M.bovis_AF2122/97           ---GGPGGPGGVGGTGGAGGLGGTLYGAGGHGGAGGPGP-----------
Rv3345c|M.tuberculosis_H37Rv        GLNGGDGSDGGNGGTGGNGGRGGLLVGNGGAGGAGGVGGDGGKGGAGDPS
Mflv_5091|M.gilvum_PYR-GCK          ----AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG-----------
Mvan_1264|M.vanbaalenii_PYR-1       ----AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG-----------
MSMEG_0868|M.smegmatis_MC2_155      GPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGG
TH_3810|M.thermoresistible__bu      ----NVGFFS--------------LFNLGGAGGWGG--------------
MAB_4284c|M.abscessus_ATCC_199      ---IGSGNTTNTEIGSHNQANIGTSTSAGGSAAVGGNAG-----------
MLBr_01183|M.leprae_Br4923          ----QYQAHASQGATNHQDLIQSLLTSSSAYAGTETANH-----------
MAV_4827|M.avium_104                ----GAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLP----------
                                                                 . ..                 

MUL_3318|M.ulcerans_Agy99           -------AAAGANGG-----------------------------------
MMAR_2033|M.marinum_M               -------GVAGANGG-----------------------------------
Mb1487c|M.bovis_AF2122/97           ------IGGVGGHGG------VGGAAGLLG--------------------
Rv3345c|M.tuberculosis_H37Rv        FAVNNGAGGNGGHGGNPGVGGAGGAGGLLAGAHGAAGATPTSGGNGGDGG
Mflv_5091|M.gilvum_PYR-GCK          -----AVGAAGAAG------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -----AIGTAGVAG------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      TVDGHAIGGNGGNGGNGS--------------------------------
TH_3810|M.thermoresistible__bu      ---------SGVDG------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----LAGNAGLAGN-----------------------------------
MLBr_01183|M.leprae_Br4923          ---------DSL--------------------------------------
MAV_4827|M.avium_104                ---------DYLYVP-----------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           -------------------------------AGQTGLAG-----------
MMAR_2033|M.marinum_M               -------------------------------AGQTGLAG-----------
Mb1487c|M.bovis_AF2122/97           ----------VGGHGGAGGHG------AAGIAGAAGKGG-----------
Rv3345c|M.tuberculosis_H37Rv        IGATANSPLQAGGAGGNGGHGGLVGNGGTGGAGGAGHAGSTGATGTA---
Mflv_5091|M.gilvum_PYR-GCK          ---------------------------TVGTAGATGGTG-----------
Mvan_1264|M.vanbaalenii_PYR-1       ---------------------------AAGTAGATGGTG-----------
MSMEG_0868|M.smegmatis_MC2_155      -------------------------TTAAGGNGGTGGTGRVIAEGTGSTA
TH_3810|M.thermoresistible__bu      -------------------------------VDVVGGNP-----------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------AGLAGNAG-----------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------------VDPEPGDDE-----------
                                                                                      

MUL_3318|M.ulcerans_Agy99           ---TDGGTGGASGEGGAGGKGGLLF----------GAGGEGGAGGTGGAG
MMAR_2033|M.marinum_M               ---TDGGTG---GVGGAGGKGGLLF----------GAGGEGGAGGTGGAG
Mb1487c|M.bovis_AF2122/97           -IFPDGSNGGAGGDAGDGGTGGRGG----------WLAGAGGAGGDGGIG
Rv3345c|M.tuberculosis_H37Rv        -LQPTGGNGTNGGAGGHGGNGGNGG----------AQHGDGGVGGKGGAG
Mflv_5091|M.gilvum_PYR-GCK          ----TGANGGAGGVGGVGGTGAAG--------------AAGGAGGLGETG
Mvan_1264|M.vanbaalenii_PYR-1       ----VGGNGGAGQAGGIGGTGAAG--------------AAGQAGTAGETG
MSMEG_0868|M.smegmatis_MC2_155      EGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDG
TH_3810|M.thermoresistible__bu      -------DGGTPGAHGESHTPGVYT---------------DRQGEDGEDG
MAB_4284c|M.abscessus_ATCC_199      ----LAGNAGLAGNAGLAGNAGLAG-------------NAGLAGNAGLAG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --LAYSAVGEEDAESPTVVIEKLFLP------------EDSEPRRRPVLL
                                                                                      

MUL_3318|M.ulcerans_Agy99           GTGGAGGDGLAATTAGGTGGNAGDGGEGGAGGNAGAGGAGGQG--GLFGN
MMAR_2033|M.marinum_M               GAGGTGGDGLAATTAGGTGGNAGDGGGGGTGGNAGDGGAGGQG--GLFGN
Mb1487c|M.bovis_AF2122/97           GTGGAGGAGFSRALIVA-GDNGGDGGNGGMGGAGGAGGPGGAG--GLISL
Rv3345c|M.tuberculosis_H37Rv        GSGGAGGNGFDAATLGSPGADGGMGGNGGKGGDGGKAGDGGAGAAGDVTL
Mflv_5091|M.gilvum_PYR-GCK          TTGGAG--GVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQG
Mvan_1264|M.vanbaalenii_PYR-1       VTGGVG--GIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQG
MSMEG_0868|M.smegmatis_MC2_155      GTGGAG--GMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQA
TH_3810|M.thermoresistible__bu      TGTGIG----------------GRGGNGGSSSGTHPMAEDG---------
MAB_4284c|M.abscessus_ATCC_199      NAGLAGNAGLAGN--AGLAGNAGLAGNAGLAGNAGLAGNAGLAG------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVP-------
                                                                                      

MUL_3318|M.ulcerans_Agy99           AGT---------------TGAGGDGGNGGNGG------------------
MMAR_2033|M.marinum_M               AGT---------------TGAGGDGGNGGNGG------------------
Mb1487c|M.bovis_AF2122/97           LGG---------------QGAGGDGGDGGAGG------------------
Rv3345c|M.tuberculosis_H37Rv        AVN---------------QGAGGDGGNGGEVG------------------
Mflv_5091|M.gilvum_PYR-GCK          GQG-------------LQGGKGGDGGAGGKGGDADSMGS-----------
Mvan_1264|M.vanbaalenii_PYR-1       GQG-------------LQGGQGGDGGTGGTGGDATSMGE-----------
MSMEG_0868|M.smegmatis_MC2_155      GYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTA
TH_3810|M.thermoresistible__bu      -----------------EHVKALDGRPGLDGG------------------
MAB_4284c|M.abscessus_ATCC_199      -----------------NAGLAGNAGLAGNAG------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------TEQAPAPPPVQASAPQPK----------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           -------LAGNGGAGGNGDASNPN--------------------------
MMAR_2033|M.marinum_M               -------LAGNGGAGGNGDASNPN--------------------------
Mb1487c|M.bovis_AF2122/97           -------VGGDRGAG-ANGNQAVN--------------------------
Rv3345c|M.tuberculosis_H37Rv        -------VGGKGGAGGVSANPALNGSAGANGTAPTSGGNGGNGGAGATPT
Mflv_5091|M.gilvum_PYR-GCK          -------AGATGGKGGNGGNGGRGGLFG----------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------AGATGGKGGNGGNGGRGSLFG----------------------
MSMEG_0868|M.smegmatis_MC2_155      IGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGG---------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------LAGNAGLAGNAGLAGNAAVAG----------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------ISVPEPVAAPKPLSPPVAAPLP---------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------GGTGGNAAN----------------------PGAGGAGGAGG
MMAR_2033|M.marinum_M               --------GGTGGNGAN----------------------PGAGGAGGAGG
Mb1487c|M.bovis_AF2122/97           -----AGAGGAGGHGGD----------------------PGAGGAGGTGG
Rv3345c|M.tuberculosis_H37Rv        VAGENGGAGGNGGHGGS----------------------VGNGGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK          -------KGGNAGNGAD----------------------GGTGGAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1       -------RGGNAGNGGN----------------------GGTGGNGGNGG
MSMEG_0868|M.smegmatis_MC2_155      -----AAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNG
TH_3810|M.thermoresistible__bu      ----------NGSHGGN----------------------GGHGGRGGFLG
MAB_4284c|M.abscessus_ATCC_199      ----------NAAVAGN-------------------AAVAGNAAVGGVLN
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------AAPPPAAPP---------------------LPEAPPIPAAPP
                                                                                      

MUL_3318|M.ulcerans_Agy99           NGSR---------------TGAPGTTGNTPTT-------------AAGHG
MMAR_2033|M.marinum_M               NGSR---------------TGAPGTTGNTPTT-------------AAGHG
Mb1487c|M.bovis_AF2122/97           AGST---------------IGAHGAAGASPTS--------------GGNG
Rv3345c|M.tuberculosis_H37Rv        NGVAGTGLALNGGNGGNGGIGGNGGSAAGTGGDGG----------KGGNG
Mflv_5091|M.gilvum_PYR-GCK          TGG----------------TGGAGGTGG-----------------TGGTG
Mvan_1264|M.vanbaalenii_PYR-1       TGG----------------TGGNGGTGG-----------------TGGTG
MSMEG_0868|M.smegmatis_MC2_155      TGGA---------------TGGRGGDGAGASVWKANGQHSTGQTDTGGNG
TH_3810|M.thermoresistible__bu      IGGS------------------------------------------GGWG
MAB_4284c|M.abscessus_ATCC_199      TGVSG-------------AIGGSSHVGGAINES------------LGGSG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VVPVP--------------VVVPPVPVPVPVR-------------IPVPD
                                                                                      

MUL_3318|M.ulcerans_Agy99           GKGGDGFNPAT---------------------------------------
MMAR_2033|M.marinum_M               GKGGDGFSPAT---------------------------------------
Mb1487c|M.bovis_AF2122/97           GAGGNGAHFSS------------------GGK------------------
Rv3345c|M.tuberculosis_H37Rv        GAGANGQDFSASANGANGGQGGNGGNGGIGGKGGDAFATFAKAGNGGAGG
Mflv_5091|M.gilvum_PYR-GCK          GIGGAGSTGGTGGTGGTGG-------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GIGGAGSTGGTGGTGGTGG-------------------------------
MSMEG_0868|M.smegmatis_MC2_155      GRGGDGGTFVNAGANGNGG-------------------------------
TH_3810|M.thermoresistible__bu      GHGGNG--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SVGGSTAVGGGAHTG-----------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PVSPPQLLAPPRLS------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               --------------------------------------------------
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        NGGNVGVAGQGGAGGKGAIPAMKGATGADGTAPTSGGDGGNGGNGASPTV
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           SGQDGGSG-GKGGDAGQFGNGGNGGNG---AAGDAAG----SGHTGGNGG
MMAR_2033|M.marinum_M               SGQDGGSG-GKGGDAGRFGNGGNGGNGGNGAAGDAAG----SGHTGGNGG
Mb1487c|M.bovis_AF2122/97           AGGNGGAG-GAGGHGGLVGNGGAGGAGGNGANGAAGTNASDSGAVGGKGN
Rv3345c|M.tuberculosis_H37Rv        AGGNGGDG-GKGGSGGNVGNGGNGGAGGNGAAGQAGTPGPTSGDSGTSGT
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155      AGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGG
TH_3810|M.thermoresistible__bu      -GDTDADG-GNGGDGGNGGSAGRGGTG---------------GLRGVFGI
MAB_4284c|M.abscessus_ATCC_199      VGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGG-----GAHTGVGG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                VPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGE-----GTPPKPDG
                                                                                      

MUL_3318|M.ulcerans_Agy99           AGGGG---------GNAGQFGEPGT------------GGSGGNGGKGG--
MMAR_2033|M.marinum_M               AGGGG---------GNAGQFGEPGT------------GGSGGNGGKGG--
Mb1487c|M.bovis_AF2122/97           SGGNG---------GQGGAGGDGGTL-----------AGNGGAGGTGG--
Rv3345c|M.tuberculosis_H37Rv        DGGAG---------GNGGAGGAGGTL-----------AGHGGNGGKGG--
Mflv_5091|M.gilvum_PYR-GCK          TGGTG---------GTGGTGGTGGAG-----------DGTGGTGGTGG--
Mvan_1264|M.vanbaalenii_PYR-1       TGGTG---------GTGGTGGTGGAG-----------DGLGGTGGTGG--
MSMEG_0868|M.smegmatis_MC2_155      NGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNG
TH_3810|M.thermoresistible__bu      NGGNG----------------------------------RAGLGGRGX--
MAB_4284c|M.abscessus_ATCC_199      GVSTG---------VGVGSHVGGGIS-----------ESLGGSGSVGG--
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                PGNYG-----------GGHVPTP---------------GAGGSGGSGG--
                                                                                      

MUL_3318|M.ulcerans_Agy99           --DGAAG------------------------------------------G
MMAR_2033|M.marinum_M               --DGAAGGLAQAGGNGGEGGAGGNAGAGGLSGTGDSTGNAGTGGNGGAGG
Mb1487c|M.bovis_AF2122/97           --RGADGGLGGSG---AEGANATTAGE--------------RGQDGGKGG
Rv3345c|M.tuberculosis_H37Rv        --NGGQGGIGGAGERGADGAGPNANGA--------------NGENGGSGG
Mflv_5091|M.gilvum_PYR-GCK          --TGGQGGQGGQGG------------------------------TGGTGG
Mvan_1264|M.vanbaalenii_PYR-1       --TGGFGGQGGQGG------------------------------TGGTGG
MSMEG_0868|M.smegmatis_MC2_155      DADGHRGGKGGDGGEALIRATVIGSNAS-------------GTATGGDGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------------------------------------------STAVG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------------------GHVPTPG
                                                                                      

MUL_3318|M.ulcerans_Agy99           NGGTGG--------------------------------------------
MMAR_2033|M.marinum_M               NGGTGGDGSDGGPGGAGGKGGNSGPGGTNGTGGHGGNGGTGGDGGDGASG
Mb1487c|M.bovis_AF2122/97           NGGVGGTGGN----------------------------------------
Rv3345c|M.tuberculosis_H37Rv        NGGDGGAGGNGGAGGKAQA-------------------------------
Mflv_5091|M.gilvum_PYR-GCK          QGG-LGGGGGTG--------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       QGG-LGGVGGTG--------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      NGGTLGATNGTGGAATIVA-------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GGAHTGVGGG----------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                AGGSGGSGGGHVP-------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               VGLGKAGGTGATGGNGGNAGSGGAAGTGGTGGTNGSAGTGGTGGTGGNGG
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               AGDKGAVGDSGFAGGTGGAGGTGGNSGPGGTNGTGGHGGNGGTGGDGGDG
Mb1487c|M.bovis_AF2122/97           ------------------------------------------------AV
Rv3345c|M.tuberculosis_H37Rv        ------------AGYTDGATGTGGDGGNGGDGGKAGDGGAGENGLNSGAM
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------YNVVQA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               ASGVGQGKAGGTGATGGNGGNAGSGGAAGTGGDASGGGTNGSAGTGGTGG
Mb1487c|M.bovis_AF2122/97           APG----ANGGHGGNGGNPGFSG---------------------------
Rv3345c|M.tuberculosis_H37Rv        LPGGGTVGNPGTGGNGGNGGNAG---------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------GQGGTGGTGGQGG---------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ----------GTGGTGGTGGQGG---------------------------
MSMEG_0868|M.smegmatis_MC2_155      NPQASGTATDGHGGSGINGGHGG---------------------------
TH_3810|M.thermoresistible__bu      -------X------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               TGGNGGDGDKGAVGDSGFAGGTGGAGGTGGNSGPGGTNGTGGHGGNGGTG
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               GDGGDGASGVGQGKAGGTGATGGSGGNAGSGGAAGTGGNGGTNGNAGTGG
Mb1487c|M.bovis_AF2122/97           --------------------AGGLGGLSGDGVTR---AAQGATPD-----
Rv3345c|M.tuberculosis_H37Rv        --------------------VGGTGGKAGTGSLTGLDGTDGITPNGGNGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------TGGTGGTGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------TGGTGGTGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------NGGQGTIEANGPSA----------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           ------------------------------------------------IG
MMAR_2033|M.marinum_M               TGGTGGNGGDGDKGAVGDSGFAGGTGGNGGTGGNSGPGGTNGTGGHGGNG
Mb1487c|M.bovis_AF2122/97           ------------------------------------------------FA
Rv3345c|M.tuberculosis_H37Rv        NGGNGGKGGTAGNGSGAAGGNGGNGGSGLNGGDAGNGGNGGGALNQAGFF
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ---------------------------------------------VASGI
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------------------V
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------------------------------------------------TP
                                                                                      

MUL_3318|M.ulcerans_Agy99           GTGGIGGDGRNGSTGAI-GGNGGTGGTG----------------------
MMAR_2033|M.marinum_M               GTGGDGGDGRNGSTGAI-GGNGGTGGTGGIGGTAGTGGTGGSAGSAGTGG
Mb1487c|M.bovis_AF2122/97           DTGGKGGNGGNGANAVAPGGTGASGGAGG---------------------
Rv3345c|M.tuberculosis_H37Rv        GTGGKGGNGGNGGAGMINGGLGGFGGAGGGGAVDVA--------------
Mflv_5091|M.gilvum_PYR-GCK          GTGGAGGDGGLGGLGGF-GGSGGTGGQGGLGG------------------
Mvan_1264|M.vanbaalenii_PYR-1       GTGGAGGDGGLGGLGGF-GGVGGTGGQGGQGG------------------
MSMEG_0868|M.smegmatis_MC2_155      GAGGNGGDGIDGGLGGN-GGDGVVNTTANAAN------------------
TH_3810|M.thermoresistible__bu      XXGGGVGAAVRSGNGVFSGGGGTP--------------------------
MAB_4284c|M.abscessus_ATCC_199      NTGVGVGSHVGGGISESLGGSGSVGGSTAVGG------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GTGGPGGTGGSGGGHVPTPGAGTPGGSGGGHLPFPG--------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               TGGNGGAGDSGASGGTGGTGGEGGAGIGGKDGGTGGTGGTGGTGGAGVVS
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               GLSAFPGGIGGAGGAGGQGGQATGGGNAGDGGTGGQGGTGGQGATSLFEA
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               SSGGTGGAGGAGGLGGQAADGGNAGDGGTGGQGGTGGQGAAGPTVNDTAG
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               DGGAGGDGGVGGAGGQGGQATDGGNAGNAGDGGNGGQGGTGGQGAAAPSA
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           -------------------------------------GTGGTGGKSLG--
MMAR_2033|M.marinum_M               AKAAGNGGAGGVGGDGGNGADASGGGNGGDGGKSGGGGTGGTGGKSLG--
Mb1487c|M.bovis_AF2122/97           -----------------------------------NAGAGGKGGENIIGD
Rv3345c|M.tuberculosis_H37Rv        ---------------------------------ATTGGAGGNGGAGGFAS
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------PGGSTGGAGGAGG--Q
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------PGGSTGGAGGAGG--Q
MSMEG_0868|M.smegmatis_MC2_155      ----------------------------------PGSATGTATGGDGGKA
TH_3810|M.thermoresistible__bu      -------------------------------------SAGFGVPTTIQFP
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------GAHTSAINDALGGS
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ----------------------------------AGSTPGGSGGGHLPTP
                                                                                      

MUL_3318|M.ulcerans_Agy99           NLPSGDGGVGG----NAGTG-------GNGGNATDGGAG-----------
MMAR_2033|M.marinum_M               NLPSGDGGVGG----NAGTG-------GNGGNATDGGAG-----------
Mb1487c|M.bovis_AF2122/97           GGGGGNGGAGG----QGGD--------GTAGAGGDGGAG-----------
Rv3345c|M.tuberculosis_H37Rv        TGLGGPGGAGG----PGGAGDFASGVGGVGGAGGDGGAGGVGGFGGQGGI
Mflv_5091|M.gilvum_PYR-GCK          AGTAGKGGLFG----GSGSA-------GKAGATGAAGASG----------
Mvan_1264|M.vanbaalenii_PYR-1       AGVAGKGGLFG----GSGSA-------GTAGVTGASGASG----------
MSMEG_0868|M.smegmatis_MC2_155      TGTASQGGNGGPSWVQSGYG-------STLGGNATGTATA----------
TH_3810|M.thermoresistible__bu      AGSCTSRAVSR---------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GSVGGSTAVGG---------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                GAGTPGGGLGG---------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           -------GKGGDGAAGGTGGNAG--------------EFQSLLGIS----
MMAR_2033|M.marinum_M               -------GKGGDGAAGGTGGNAG--------------EFQSLLGIG----
Mb1487c|M.bovis_AF2122/97           -------GKGGDGGDGGSDPTEG-------------RGFGGLGGAG----
Rv3345c|M.tuberculosis_H37Rv        GGEGRTGGNGGSGGDGGGGISLGGNGGLGGNGGVSETGFGGAGGNGGYGG
Mflv_5091|M.gilvum_PYR-GCK          -------GKGAQGATGAQGATG------------------AQGATG----
Mvan_1264|M.vanbaalenii_PYR-1       -------GKGAQGATGAQGATG------------------AQGATG----
MSMEG_0868|M.smegmatis_MC2_155      -------GKGGEASNGGVAGNGG------------NALVMAAGTTGV---
TH_3810|M.thermoresistible__bu      --------EGIMPSSRAASARAG---------------------------
MAB_4284c|M.abscessus_ATCC_199      -------GAHTSAINESMNSSIN---------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ------FGGGHAPAPGGGLGGGG---------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           ---------KGGDGGTGGDGG---TGTPVGADGLAGTG------------
MMAR_2033|M.marinum_M               ---------KGGDGGTGGDGGNGGTGTPVGAGGLAGTG------------
Mb1487c|M.bovis_AF2122/97           --------GAGGKGGAGTLLGLTVFGDNGGAGVLGDS-------------
Rv3345c|M.tuberculosis_H37Rv        PGGPEGNGGLGGNGGAGGNGGVSTTGGDGGAGGKGGNGGDGGNVGLGGDA
Mflv_5091|M.gilvum_PYR-GCK          --------ATGAAGKAGATGAAGAAGAAGSAG------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------ATGASGAQGSAGSAGSAGVAGSAG------------------
MSMEG_0868|M.smegmatis_MC2_155      --------ATGNTATGGDGGAATTAGATGGAGGFSNIAA-----------
TH_3810|M.thermoresistible__bu      --------AACASSTSRSRRSFCCSRA-----------------------
MAB_4284c|M.abscessus_ATCC_199      --------ASHSSSMNESFGSSMGSHGAAGTGFEAQG-------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                ---------GHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-----------
                                                                                      

MUL_3318|M.ulcerans_Agy99           ----------------GAGGFG----------------------------
MMAR_2033|M.marinum_M               ----------------GAGGFG----------------------------
Mb1487c|M.bovis_AF2122/97           ------------TDPDGSGGAG----------------------------
Rv3345c|M.tuberculosis_H37Rv        GSGGAGGNGGIGTDAGGAGGAGGAGGNGGSSKSTTTGNAGSGGAGGNGGT
Mflv_5091|M.gilvum_PYR-GCK          --------TTGAQGSAGTNGA-----------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------TTGAQGSAGTNGA-----------------------------
MSMEG_0868|M.smegmatis_MC2_155      ----IHGAITDSTAISGHGGAG----------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --IFPGGQTGQNGTDSKAG-------------------------------
MMAR_2033|M.marinum_M               --VFPGGQTGQNGTDGKAG-------------------------------
Mb1487c|M.bovis_AF2122/97           ---GAGGAGGAGGDPTI---------------------------------
Rv3345c|M.tuberculosis_H37Rv        GLNGAGGAGGAGGNAGVAGVSFGNAVGGDGGNGGNGGHGGDGTTGGAGGK
Mflv_5091|M.gilvum_PYR-GCK          --NGANGSQGAAGKAGATG------------------------TTGATG-
Mvan_1264|M.vanbaalenii_PYR-1       --NGANGSQGAAGKAGATG------------------------TTGATG-
MSMEG_0868|M.smegmatis_MC2_155      --NGGNGGKGADGWVQAYD------------------------PAGPVGS
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---HAQGHASETAHTTLPGAEHH---------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               --------------------------------------------------
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        GGNGSSGAASGSGVVNVTAGHGGNGGNGGNGGNGSAGAGGQGGAGGSAGN
Mflv_5091|M.gilvum_PYR-GCK          -------AAGEDGDAGSGGSG-INGGAGGAGG------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------AAGDAGDPGSEAVD-INGGAGGAGG------------------
MSMEG_0868|M.smegmatis_MC2_155      KIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSV--------WKSGGQ
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               --------------------------------------------------
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        GGHGGGATGGDGGNGGNGGNSGNSTGVAGLAGGAAGAGGNGGGTSSAAGH
Mflv_5091|M.gilvum_PYR-GCK          -AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GA
Mvan_1264|M.vanbaalenii_PYR-1       -AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GA
MSMEG_0868|M.smegmatis_MC2_155      TADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGN
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               --------------------------------------------------
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        GGSGGSGGSGTTGGAGAAGGNGGAGAGGGSLSTGQSGGPRRQRWCRWQRR
Mflv_5091|M.gilvum_PYR-GCK          GGSGGSGGSGGSGGSGGAAGDSDD--------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GGSGGSGGSGGAGGSGGAAGDSD---------------------------
MSMEG_0868|M.smegmatis_MC2_155      GGNGGNGGADGTPGTAGTTGANNP--------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2033|M.marinum_M               --------------------------------------------------
Mb1487c|M.bovis_AF2122/97           --------------------------------------------------
Rv3345c|M.tuberculosis_H37Rv        RWLGRQRRRRWCRWQRRCRRQRWRWRCRQRRLRRQWRQGRRRCRPWLHRR
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      --------------------------------------------------
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

MUL_3318|M.ulcerans_Agy99           ------------------------
MMAR_2033|M.marinum_M               ------------------------
Mb1487c|M.bovis_AF2122/97           ------------------------
Rv3345c|M.tuberculosis_H37Rv        RGRQGRRWRQRRFQQRQRSRWQRR
Mflv_5091|M.gilvum_PYR-GCK          ------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------
MSMEG_0868|M.smegmatis_MC2_155      ------------------------
TH_3810|M.thermoresistible__bu      ------------------------
MAB_4284c|M.abscessus_ATCC_199      ------------------------
MLBr_01183|M.leprae_Br4923          ------------------------
MAV_4827|M.avium_104                ------------------------